LOCUS       NZ_JAQESL010000010     18907 bp    DNA     linear   CON 29-FEB-2024
DEFINITION  Coprococcus sp. AM97-35 AM97-35.Scaf10, whole genome shotgun
            sequence.
ACCESSION   NZ_JAQESL010000010
VERSION     NZ_JAQESL010000010.1
KEYWORDS    WGS; RefSeq.
SOURCE      Coprococcus sp. AM97-35
  ORGANISM  Coprococcus sp. AM97-35
            Bacteria; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae;
            Coprococcus.
REFERENCE   1  (bases 1 to 101575)
  AUTHORS   Lin,X., Hu,T., Chen,J., Liang,H., Zhou,J., Wu,Z., Ye,C., Jin,X.,
            Xu,X., Zhang,W., Jing,X., Yang,T., Wang,J., Yang,H., Kristiansen,K.,
            Xiao,L. and Zou,Y.
  TITLE     The genomic landscape of reference genomes of cultivated human gut
            bacteria
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 101575)
  AUTHORS   Zou,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-NOV-2022) BGI Reaserch, BGI-Shenzhen, Beishan
            Industrial Zone, Shenzhen 518083, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. v2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100x
            Sequencing Technology             :: MGI
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/29/2024 10:49:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,361
            CDSs (total)                      :: 3,321
            Genes (coding)                    :: 3,266
            CDSs (with protein)               :: 3,266
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 6 of 55
            Pseudo Genes (incomplete)         :: 54 of 55
            Pseudo Genes (internal stop)      :: 2 of 55
            Pseudo Genes (multiple problems)  :: 5 of 55
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:11:55
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 18907
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAQESL010000010.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..18907
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..18907
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..18907
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5796:8907](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5797..8907
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            complement(<1..697)
                     /locus_tag="PG840_RS09120"
     CDS             complement(<1..697)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015526860.1"
                     /locus_tag="PG840_RS09120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RNA-binding protein"
                     /protein_id="WP_270613543.1"
                     /transl_table=11
                     /translation="MANETMNLNTPILTLDSDTVLETAQSKADLIWHDIQNAYRTRKIL
                     TGILGGIEKTEAGSLIAIIYYKDYRAVIPISEMMINLIQDETHDYGDFSLRQNKVLNNM
                     LGSEIDFVIKGLDTKSRSIVASRKDAMLKKRQIFYFDQDSSGQNKIHEDRIVQARVIAV
                     AEKVVRAEIFGVETSILARDLSFDWLGDARERFQVGEHILVRILAIQGDSPETLSIHAD
                     VKSVEGNTSK"
     gene            complement(723..2729)
                     /locus_tag="PG840_RS09125"
     CDS             complement(723..2729)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004223624.1"
                     /locus_tag="PG840_RS09125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type IV secretory system conjugative DNA transfer
                     family protein"
                     /protein_id="WP_025579348.1"
                     /transl_table=11
                     /translation="MNRKWWKFLFLLPISVCTLYAGGYAAQFIKNYQEWTSAGNFAGNG
                     TYPQAASLHPLVCFHTALTDFPYNLYGIFLCLVLFGLLTFLLMRMGYDRNGEISDHDRN
                     LNYSTKGTYGTSGFMTPDEMMKVLELTGDVKKNKGTILGKLNGKAVCLPYQTRMNKNIA
                     VYGASGSMKSRAFARNMIFQCVARGQEGNNASGESLIITDPKSELYESMSAYLENEGYV
                     VKAFNLVNPENSDSWNCLGEINGQETMAQVFADVIIQNTGSGKGDHFWDNAEMNLLKAL
                     VLYVDQGFPPEARNIGQVYKLLTMSSEKELNSLFDLLPVSHPAKVPYCIYKQASDTVRS
                     GVIIGLGARLQVFQNKLIRQITSYDEIDLTLPGKQKCAYFCITSDQDSTFDFLSSLFMT
                     FIFIKLVRYADKYGEEGKLPVAVHILADELANTGAILELNKKISVIRSRNLSISCIFQN
                     LPQMQNRYPYNQWQEIIGNCDTQLFLGCTDEVTATFISNRSGDVTVGVSSEAKQLNSWR
                     VSDYTPEYRQTKSIGKRKLLTPDEILRLPLDTALVILRGQKVLKVEKYDYTLHPDAKKL
                     TPRKASEHIPEWRKNGSSEETEYRPQPSPGSAKRKRRSSSASIAKQKPHFTSEPVYQEP
                     TPDDFMEDFFQENFIEDSPDSGMVPLDKDSIMS"
     gene            complement(2719..3825)
                     /locus_tag="PG840_RS09130"
     CDS             complement(2719..3825)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004223623.1"
                     /locus_tag="PG840_RS09130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_226854332.1"
                     /transl_table=11
                     /translation="MIKTDSIKYQLLEMVGLCGEFPSGQLNRLIESDSYAEKVVTDLKQ
                     SKLIRTHYKDGLRGYRLTKRAKELLLSQNPCRFQNYLTGNAETNLIRSELPRRLRLHQK
                     AETYLTLSHAGIPFFPDEKPLLFSESSEAATFPVRSLPLFYSSREIKNLGASTTKIKNS
                     RCIGILMAPHCVYAVYNTGNTLLKWEYKTEVRLNAFLQHYLQGLPYHGPPTVYAIMTGS
                     DMDMAFRLLTSTGGYKKTLFMLDTSYEHFYFLPNNSYGEYLLRLLVQPQRMMQLNQLLL
                     SDCFPQREDLPIEHDGIDSQENPILLAYDFDMQRINRFNTGLNVYGLSGNLICFDFQLP
                     CLKKYLTADIHFSSIDFQKFKRRFFNEP"
     gene            complement(3965..4630)
                     /locus_tag="PG840_RS09135"
     CDS             complement(3965..4630)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005340398.1"
                     /locus_tag="PG840_RS09135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6100 family protein"
                     /protein_id="WP_025579351.1"
                     /transl_table=11
                     /translation="MNTKTVFDRLQSIDDEVQKLHNTIFALKTTDIQAYADKYEELSIS
                     AALRSERIACQLRNLVYTTTDTGKKDYLKQAAAVQGIKISFSNSVLSITMPGLLPKRKL
                     RTNTAFLHEPLNLALQTYVTEHSIPLYKRCVVCFSQIYDQSLSLQRIRDYDNLEFKQIL
                     DTIASYVLVDDTGLFCDSYHTTELGNYDHTVIFVMEPEIFPGWLKDRKESIKTISEIS"
     gene            complement(4638..5168)
                     /locus_tag="PG840_RS09140"
     CDS             complement(4638..5168)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004223618.1"
                     /locus_tag="PG840_RS09140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF5697 family protein"
                     /protein_id="WP_054338136.1"
                     /transl_table=11
                     /translation="MKTRNEIYQGEGAQLLRFITTYHSLQYEQVLRLFSKNRESIKSLI
                     TSLVKQKRIIYDKENGLLFDSQESANNPDYGMIASFWVLLDFKTAIVYHTDGEFPVKLN
                     FFSKDEWYEVLYVPQEQEYLINHVMESQTKSDAKRLVVLETEEQAAKIHITGVIAFCLV
                     DSSTGSVSYYAKK"
     gene            5569..5742
                     /locus_tag="PG840_RS09145"
     CDS             5569..5742
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004223616.1"
                     /locus_tag="PG840_RS09145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="plantaricin C family lantibiotic"
                     /protein_id="WP_114002469.1"
                     /transl_table=11
                     /translation="MRKFDRTNMKYNNPAGDLLTELEAADLTSNKVDSLASSGVVCTIS
                     VECGSIFTLACC"
     CDS_motif       5569..5643
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRKFDRTNMKYNNPAGDLLTELEAA"
                     /locus_tag="PG840_RS09145_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       5644..5742
                     /prepeptide="core"
                     /locus_tag="PG840_RS09145_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.00"
                     /molecular_weight="3061.5"
                     /monoisotopic_mass="3059.5"
                     /core_sequence="DLTSNKVDSLASSGVVCTISVECGSIFTLACC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRKFDRTNMKYNNPAGDLLTELEAA"
                     /leader_location="[5568:5643](+)"
                     /alternative_weights="3079.5"
                     /alternative_weights="3097.5"
                     /alternative_weights="3115.6"
                     /alternative_weights="3133.6"
                     /alternative_weights="3151.6"
     gene            5797..8907
                     /locus_tag="PG840_RS09150"
     CDS             5797..8907
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="PG840_RS09150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_117843977.1"
                     /sec_met_domain="DUF4135 (E-value: 6.5e-103, bitscore:
                     337.3, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.3e-67, bitscore:
                     219.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKSSYLSERVYDAIPSEINMESLEYWKKILKEEGLQYVKKNHLE
                     YFFGFINNCAFSSHEKSQPRNFVKLSLNKKAFRHEGEKMVFGAFYDPFVQEANRQLREI
                     VIQRRYINESILFDFQQFLFNSLNNLCIRTLIYEMHICGQEGVLRGNESEQYQYYIDHF
                     LKDKQYLNDLFSLYPVLERRINEIIQNAIDIYKEVIERIEKDADVLMKKFNITEKGFVV
                     NHLSTDFSDSHKKGRRVFCVEFVSGDKILYKPRSLQNEIKLQEITNYFYRICNLGSYEY
                     SILDKEMYGWCEIVIQRDCKSIEELSRYYQRIGIILFINYLLEGGDIHFENLIACNEYP
                     VIIDAETFIGNIEENNGKSAAEKVASLLRKSVLYSGILPFYSWNNAGDTGINMSAISGE
                     EGQKFPIKIPFIINPKSVNMRVVYDYPVSKGNHNLAMLKGRFIQPSEFADKIIQGFESA
                     YLGAMENTETLLRIIQQYGELEVRYLIRNTQQYAIVLSSSYHPELLVDGGARNLFFYSL
                     ANGNLQNQRSRSLIEYEIEDLLSGDIPYFYFRGSKKNIYTWDGREVKDFFSKPALQQIE
                     ENIQNLSYKNLEQQTQYIKITFNMENAGTRKIKNKRLKLDLYSNMAKTAEELAKELLDK
                     IGTNAIYSEDGADVNWIGVKLFGIKENQWMIQALPNTLYDGTVGINLVFHLYEWIYHDR
                     KYHKICEVLDNRLLRYIDTISEGEQNIEDFNTGIFSGEGSILYTLGILYEIYDDIKYKE
                     YFDKWLNCMETLILEDRLFDMISGNSGIVLVLINMYRKTKKPIYLQKAIQIAEQLIENM
                     ITENGKVGWKSEVVPEVLAGFAHGNSGFIELFSRLYEVYPQTKYLDILSSLVEYENSLY
                     SEKDNNWIDLRKFSEVDQHKSQPIAWCHGAAGILLSRLTLYNAIKNLGETALLQQAIKD
                     ISLAKNKLIEDGLHAGFCLCHGNMGNLLILKRYAEIFDDKQVRSICDSRFEQILEFLNE
                     ENILPTELYNPGFMTGLSGIAYALLKYKMPKLPLLIGVEGIYDRNEV"
     gene            8888..9430
                     /locus_tag="PG840_RS09155"
     CDS             8888..9430
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004223609.1"
                     /locus_tag="PG840_RS09155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_054338131.1"
                     /transl_table=11
                     /translation="MIEMKFSKNDEEDGLFRISSRDIVGFYNCSSKQERKITDIIKCYG
                     TTKSIKEVELKNMKPEDNVTVSRYIERNVGSIINKDYVIEGFLGMGKLSDCKDEMVSRL
                     DISKRYCLEILVAFLQEADIIILHEMFENVWNHTIEEILVEFSLRGAVVVFSEHGEESL
                     MKLPMHSYDLSGRCVGW"
     gene            9579..10346
                     /locus_tag="PG840_RS09160"
     CDS             9579..10346
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004223606.1"
                     /locus_tag="PG840_RS09160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_114002467.1"
                     /transl_table=11
                     /translation="MERVLIISYIISMILTAGFIYCIYREKYWVFEFVNRIKKPIQQLV
                     YVFLMLLSSYAYICFSLLIKADFNAVICAVLLLLLIWAMDYLFSLCFKKNDLGISEKKR
                     YIFMAYVGACISGFIIASRDASKMALEIPNITISVLIGAYVPFTLLLEDGKKGKVELQS
                     MKEEWEEKYKKTFRERKVKDILSALLFAMVYGVLLVGALSPAQNIINDIASGIGMGMAT
                     VVVAFVGLVEVKNRLTKRRNKREDADQEKSDTE"
     gene            10528..10857
                     /locus_tag="PG840_RS09165"
     CDS             10528..10857
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009261866.1"
                     /locus_tag="PG840_RS09165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF1648 domain-containing protein"
                     /protein_id="WP_054338147.1"
                     /transl_table=11
                     /translation="MKLVGSRKLTWGICSIGVLLAIVSVFFLPQIIPVHFANGIADDFG
                     NKVEIFLFPILLIIITLLTGKENIKYFLTHSKTFLTDIQYNLMIDGVLGIVLIAEIYVI
                     YASFV"
     gene            10908..11324
                     /locus_tag="PG840_RS09170"
     CDS             10908..11324
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004071281.1"
                     /locus_tag="PG840_RS09170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF3788 domain-containing protein"
                     /protein_id="WP_054338130.1"
                     /transl_table=11
                     /translation="MIDMQNQEEIPILEDFAAYIRNPVFMKFCSEIKKKYRCHEKIEFS
                     RCSLERGWNVKFKKSGKSLCTIYPREGYFTVLVVIGSKVKEAVENILCDCAPELRELYE
                     KTRWGNGQKWLMIDLEDQGEMFADVLQLIEIRRG"
     gene            11378..11896
                     /locus_tag="PG840_RS09175"
     CDS             11378..11896
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /locus_tag="PG840_RS09175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="WP_054338129.1"
                     /transl_table=11
                     /translation="MKTYENKEELKAEIKRAYDKYIAEFKDIPESLKDKQCMEVDRTPA
                     ENLAYQVGWTALVLKWENDEQAGLPVKTPSDGFKWNQLGELYQWFTDTYAHLSLKELMG
                     MLDDNIQKIFTMIDSMTEEELFLPHKRKWADEATKTAVWEVYKFIHVNTVAPFGTFRTK
                     IRKWKKLLL"
     gene            complement(12212..12745)
                     /locus_tag="PG840_RS09180"
     CDS             complement(12212..12745)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004223594.1"
                     /locus_tag="PG840_RS09180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_015526878.1"
                     /transl_table=11
                     /translation="MAKKNHHPVSAEVENNPLYHDTYKLLRCYRDSTYSLMVAVRQVEI
                     QFQLEYNTSVDEFLDSIYAAGADLGDSQIEEWAKSIARSNKMIKLLLSSVDLLRKNHKH
                     GEEYYWILYYAFLSPHELKNTEEILEELEKHVPSISYRTYYRRRQAAINALSSILWGFS
                     AKGTLETLNKFFPK"
     gene            complement(12745..13962)
                     /locus_tag="PG840_RS09185"
     CDS             complement(12745..13962)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004223591.1"
                     /locus_tag="PG840_RS09185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_055154206.1"
                     /transl_table=11
                     /translation="MNYQLELKQIVDFPRCRIYREFIQTLMKDRSIRTNGGSCLFYFLI
                     LCSYANYSSSYRNIEHLTYKVVPGEWICSLKELQIHFRQKFQHQVISILDTLVEQNLLT
                     YSLHEKNKIIQYKIKDWPKDNTALSYNYPCKKDIGFFFFPIADVHKLIGLGKCSEMDAL
                     LDLWIHAVYNDPSVQGSDAGPVVYFRNQTGNPLFSYQELARRWKQSKSSVSRLLKKLED
                     TDMITLISYSGKHGSMVYLRNYLSVMFNISDVMIDKEEIAMKMQLPIHITEDTLPDKNN
                     SECVSESITDEQIIVSQEGSCVPESHIKVIVRKVAEILEIQGISCCRCPKTKYILSPLS
                     ACKDSIYLYSLRIICPWGKAAYQFELKLKPENHAVTNVPGHTPPLQHTLPAFAEIPEVL
                     LKGGVV"
     misc_feature    complement(14442..14455)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     medium, score: 25.31"
                     /tool="antismash"
     regulatory      14495..14578
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /regulatory_class="riboswitch"
     gene            14731..16380
                     /locus_tag="PG840_RS09190"
     CDS             14731..16380
                     /EC_number="2.7.7.65"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015513828.1"
                     /locus_tag="PG840_RS09190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="diguanylate cyclase"
                     /protein_id="WP_270613544.1"
                     /transl_table=11
                     /translation="MKKGKKWKKIEAFCILLIVTLLLIFVRILYQPGTESERGELYTFS
                     NGWYQLKDGKKTELKLPCFVTADKDGQIILYNDMLSEADKGKILSIRGIQDQLEVCIGD
                     RLLYQYKDNRFEKNRQMKGKIWADISLPEKIGQEVLSISYETKKNARLYVYAPMIGEFC
                     SVFRQHLLESIFSILMILGMTGLGIVSVIVFLYTRHRQIVEKRFLNVALFLILCSLWCI
                     FDSGIYQMYGSQNAAGTLISFYAFMTMPVPMLLFVQNTVSESVRGIPQVWIFLLYANAV
                     LQGILHLLFKIPFIHMLYITHLLLFTGVVSMILLLWKEYRKTQEKEVNLCLKAFGVLGI
                     SGVIALVLYWVLSIYWYESIFQFGILLYIAVLFWGLLCKVSNNIQFCLEQEVYRRMSLE
                     DRMTDMKNRKSFEMYLEEIQEGAILLENVLLLFVKIAELKKINDMSGRQMGDETVIRTA
                     RSIQSAERSVLEQQAVSFRVEGDEFAIIVKNPQKTPEEWEHFIKEEMEEECGNRQPVRL
                     KFGYSYLREKNGSLLSFSDWKQQADDMLCSNK"
     gene            16400..18325
                     /locus_tag="PG840_RS09195"
     CDS             16400..18325
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008371712.1"
                     /locus_tag="PG840_RS09195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GGDEF domain-containing protein"
                     /protein_id="WP_270613545.1"
                     /transl_table=11
                     /translation="MTYNIDFLIAAMVILLLVLWYFLGQKRAEDLNNQVFLFFAIIGIL
                     DVVAELASNYYISFPNSNCEIAAMLATTIFYLLQALLPFTVICYIQTLHDNKIISAKKM
                     FLSGVPTFILMGMILTNPFTEKLFYFDIPAGYMKGPWYMLMYYSALCHMAAALILIVIW
                     RKKLGYQKVKSLLEILLISGAGVVIQLLYHPLLTTGFGMSLGILVLFITINNPHANIDT
                     LTGLYNHLYLVRKSNELISAGKSFHIITVYLYQLKHINKIAGVQGGNSILKLTARKLGE
                     MCGKKAFRTTGKSFMILTGSLEEYEYYLTQLKRMFDGNSKLNVNNKIITMPVIISGIMN
                     AQKLGDSGLILEYAEYLEALSAKNGLTEVIQDDYQTMNGFLYNKRVEQYLHKAITEDLF
                     EIYYQPVYSTQKKCFITLEALSRLQHPELGWIAPDVFIQIAEKNHMIEQITDLQFSRVC
                     RFLGENRYLMRHLLNVKVNLSSLDLMRNDCSRHFIRIMDAYKIPHNWIQFEITETVATE
                     CNAGLRRVAEEFTAAGIGLCLDDFGSGYANLNTVMRLPFSVIKVDRSLLFDICRDEKRA
                     IFYESVVETFHKMNYHIVSEGVETQEEMEQISSWGVEMIQGYYFSKPLPEKELLELLKK
                     QDNIER"
ORIGIN
        1 ctttgctggt gttgccttcc acgcttttta catctgcatg gatagagagc gtttccgggg
       61 aatctccctg gatagctaag atccggacca gaatatgttc ccctacctgg aatcgttccc
      121 tggcatcacc cagccagtca aaagacagat ctcttgcaag gatggaagtt tctacaccaa
      181 agatttctgc ccggactact ttttcagcaa cggcaatgac tctggcctgc acaatacggt
      241 cttcgtggat tttattctgt ccggaagagt cctgatcaaa atagaaaatc tgacgtttct
      301 tcagcatagc atctttccgg ctggcaacga tgcttctgga tttggtatcc agtcctttga
      361 ttacaaagtc gatttcacta ccaagcatgt tattaaggac tttgttctgt ctaagagaga
      421 aatctccgta atcatgagtt tcatcttgga tcagattgat catcatttcc gagataggga
      481 tgactgcccg ataatcttta tagtaaataa ttgctattaa gctgccggct tcggtctttt
      541 caatacctcc cagaatgccg gtgagaattt tccgggtacg ataggcattt tggatgtcat
      601 gccagattaa atccgctttt gattgagcag tttctaatac agtatcggag tcaagggtta
      661 aaataggggt gttcaggttc attgtttcgt ttgccataaa tgttatctcc tttcaaaatg
      721 tgttatgaca tgatggaatc tttatctaaa ggaaccatgc cagagtcggg ggaatcttct
      781 ataaaatttt cctgaaagaa atcctccata aaatcatcgg gagtaggttc ctgataaacg
      841 ggttcggatg taaaatgtgg tttctgtttt gctattgacg cagaagatga acggcgtttc
      901 cttttggctg atccgggtga gggctgtggt cgatactctg tttcttccga agacccattt
      961 ttgcgccatt caggtatgtg ttccgatgct tttcttggtg tcagcttttt ggcatctgga
     1021 tgcagggtat aatcgtactt ttctactttt aggacttttt gcccacgtag gataaccaaa
     1081 gcagtatcaa gcgggagccg caagatttca tctggtgtta agagttttcg tttgccgata
     1141 gattttgtct gccggtattc cggtgtatag tcggataccc gccagctatt gagctgcttg
     1201 gcttcgctgc ttacccctac ggtcacatcg ccgctgcggt tgctgataaa ggtagcagta
     1261 acttcatctg tgcagcccaa aaagagctgg gtatcacagt tgccaatgat ttcctgccat
     1321 tggttataag gatagcggtt ctgcatctgg ggcaaattct gaaagatgca ggaaatgctg
     1381 agattccggc ttcggattac actgattttc ttattcagtt ccaggatagc tccggtgttg
     1441 gcaagctcat cagccagtat atgtacagca acaggaagtt ttccttcttc tccatactta
     1501 tctgcataac ggaccagttt gatgaagatg aaggtcataa acagggaaga taaaaaatcg
     1561 aaggtgctgt cctggtctga ggtaatgcaa aagtaagcac atttctgttt ccctggaagt
     1621 gtcagatcaa tctcatcata agaggtaatc tgccgaatga gtttattctg aaatacctga
     1681 agtctggcac ccaatccgat aataactccg cttcgcacgg tatcactggc ttgtttgtag
     1741 atgcagtaag gaacttttgc tggatgggac actgggagca gatcaaaaag actgttcagc
     1801 tccttttcgg aactcatggt cagcagctta taaacctgtc caatatttct ggcttccggc
     1861 ggaaagccct gatctacata gagaaccagg gcttttagca ggttcatctc cgcattatcc
     1921 cagaaatgat ctccttttcc ggaacctgta ttctggataa tgacatctgc aaatacctga
     1981 gccatcgttt cttgtccatt gatttcaccc agacaattcc aactatccga gttttccgga
     2041 ttgaccagat taaatgcttt tactacatag ccctcatttt ccagataagc agacatgctt
     2101 tcatagagtt cgcttttggg atcggtaatg attaaacttt ccccggaagc gttgttgcct
     2161 tcctgccctc tggcgacaca ctggaaaatc atattcctgg caaatgccct ggatttcatg
     2221 gaaccgctgg caccatacac ggcgatattt ttattcattc gtgtttgata tggaagacat
     2281 acggctttgc catttaattt tcctaaaatg gttcctttat ttttcttgac atctccggtc
     2341 agttccaaaa ctttcatcat ttcatctgga gtcatgaatc cggatgtacc gtaggttcct
     2401 tttgtagagt aatttaagtt ccggtcatgg tcactaattt ccccgtttct gtcatatccc
     2461 atacgcataa gtaaaaaagt aagaagccca aagagaacca ggcaaagaaa aatcccatac
     2521 aaattgtatg ggaaatcggt aagggcggta tgaaagcaga ccaatgggtg taaagaagct
     2581 gcttgcggat aggttccgtt gccggcaaag tttccggcag aagtccattc ctgatagttt
     2641 ttaataaatt gtgctgcgta tcctccggca tacagagtgc agacgcttat gggaagcaaa
     2701 aacaggaact tccaccattt acggttcatt gaaaaacctc cttttaaact tttgaaaatc
     2761 aatgctggag aagtgtatat ctgcagttag gtattttttc aggcagggaa gctgaaagtc
     2821 aaagcaaatc aggttcccgg atagcccata tacatttaat ccagtattga agcggttgat
     2881 acgctgcatg tcaaaatcat acgcaagcaa aataggattt tcctggctgt ctattccatc
     2941 atgttcaatt ggcagatcct cacgctgggg aaaacagtcg gacagtagta gctgattgag
     3001 ctgcatcata cgctggggtt gtaccaataa acggagcagg tattctccgt agctgttatt
     3061 gggcaggaaa tagaagtgtt catacgaagt atccagcatg aacagtgttt ttttgtatcc
     3121 accggtactg gtaaggagcc ggaaagccat atccatatca ctgccagtca tgatggcata
     3181 aacggtaggt ggcccatggt aaggaagtcc ctgaagatag tgctgcaaaa aagcattgag
     3241 tcggacttcc gttttgtatt cccattttag aagtgtattt ccggtattat aaacagcata
     3301 gacacagtga ggagccatca ggattcctat acaacgggaa tttttaattt tggtagtgga
     3361 tgctccaaga ttttttattt ctctggaaga gtaaaacaga ggaaggcttc gcacaggaaa
     3421 cgtagccgct tcgctggatt cagaaaaaag cagcggcttt tcatctggaa agaatgggat
     3481 tccggcatgt gaaagcgtta aataggtttc tgctttttga tgaagtcgca gccgtcttgg
     3541 taattcacta cgtatgaggt tggtttctgc atttccggtt aaatagtttt gaaaacgaca
     3601 gggattttgc gaaagcagca gttcttttgc ccgtttggta aggcgataac ctcgtaggcc
     3661 atctttatag tgtgttctta taagcttact ctgctttaaa tctgtaacca ccttctctgc
     3721 ataggaatca ctctcaatca atctgttaag ctgtccggaa gggaattccc cacatagccc
     3781 aaccatttcc aaaagctgat attttataga atcggttttt atcaaataag catcacctca
     3841 gttcgatttt tacctatgac agcctatact tgggtaaagt aagggcggta ttaagcataa
     3901 aaaatgcaaa gaatatggct tctttgcaga aaaattaccc atatcggaaa aagaaagaaa
     3961 aatatcagga aatttccgat atggttttga tagactcttt tctatctttc agccagccag
     4021 gaaagatttc cggttccatt acaaagataa cggtgtgatc gtaattcccc agttccgtag
     4081 tgtgatagga gtcgcaaaag agtcccgtat catcaaccag aacataggaa gcgatagtat
     4141 ctaaaatctg tttgaactcc aaattatcgt aatcacgtat ccgttgtaaa gaaaggctct
     4201 ggtcataaat ttgactaaaa cagaccacac atcttttata taacggaata gaatgttctg
     4261 tcacataagt ctgcaaggca aggtttaatg gctcatgtag aaaagcggtg ttggttcgca
     4321 atttacgttt gggcagtagt cctggcatgg taatggaaag aacactattt gaaaaagaga
     4381 ttttgattcc ctgcacagcc gcagcctgtt tcagatagtc tttctttcca gtgtcagttg
     4441 tggtatatac cagatttctg agctggcagg caatcctttc agaacgtagg gcagcactga
     4501 tactcagctc ttcgtatttg tcggcatacg cttgaatatc tgttgttttc aatgcaaaaa
     4561 tagtgttgtg aagtttttgg acttcatcat caatgctctg taaacggtca aaaacagttt
     4621 tggtgttcat acatacctca tttctttgca taatagctga cagatccggt agaggagtct
     4681 acaaggcaaa aggcaatcac gcctgtgata tgaatttttg cagcctgttc ttctgtttct
     4741 aatacaacca gccgtttcgc atcgcttttt gtctggcttt ccatgacatg attgataaga
     4801 tattcttgtt cctgggggac atagaggact tcataccact catctttaga gaaaaagttc
     4861 agtttcacag gaaattcacc gtcagtatgg tacacaatgg ctgttttgaa gtccaaaagc
     4921 acccaaaagg atgcaatcat gccataatca ggattgtttg cagattcctg gctgtcgaag
     4981 agaagcccgt tctccttatc atagataatg cgtttttgtt ttaccagact tgtgatcaga
     5041 gatttgatag actctctgtt tttggaaaag agccgtaaga cctgttcata ttgcaacgaa
     5101 tggtaagttg taatgaaccg gagcagttgg gcaccttccc cttgatagat ttcatttctt
     5161 gttttcatgg taatctccct tcattatata ataggaagtt ttacttacac tgtacgcaca
     5221 gaatacgttt tattttaggg gaagtacgct gtacgtactg tgtaagtatt ggctactgtc
     5281 agcgaaaggt ttacgggtac aaaaaaagca ccgattaagg tgctggggaa aataggaata
     5341 ctataagcaa tacctattgt aacatgggta aaattaccct tcaatcgcag aagtgtgcca
     5401 agttgtggca tatttaggaa atgataaaga cagttgaaaa ccaattagga agaaaaaatg
     5461 tcaatctata ccaaaaataa agacgaaatt cggagatagg atataataaa aatcaagata
     5521 cttaggtatc aaaaggccct agttctgaag aaaggaatgg tggatattat gagaaaattt
     5581 gacagaacaa atatgaaata taacaacccg gctggagatc ttttgacaga attagaagca
     5641 gcagatttga caagtaacaa agttgatagt ttagcttcat caggtgtggt ttgcacaatt
     5701 tctgttgaat gcggaagtat ttttacactt gcttgttgct aattaaccaa agatgatttt
     5761 agaactaggg cctggattaa gagaaaggga gataacatga aaaaatctag ttatttatct
     5821 gaaagagtgt atgatgctat tccgtctgaa ataaatatgg agtctttaga gtattggaag
     5881 aaaatactga aggaggaagg attacaatat gtaaagaaaa accaccttga gtattttttt
     5941 ggttttataa ataattgtgc ttttagtagc cacgagaaga gtcaaccacg aaattttgtg
     6001 aaattgtctt tgaacaaaaa ggcgtttagg catgagggtg agaaaatggt tttcggagca
     6061 ttttatgatc cttttgtgca agaggcaaat agacagctta gagaaatagt tatacaaaga
     6121 cgatatatca atgaatcgat tctatttgat tttcagcaat ttttgtttaa ttcgcttaat
     6181 aatctttgta tccgaacttt aatttatgaa atgcatatat gtggacaaga aggcgtgtta
     6241 aggggaaatg aatctgaaca gtatcaatat tatatcgacc attttttaaa ggataaacaa
     6301 tatttgaatg atttattttc gctttatcca gtgttagaaa gaaggataaa tgaaattata
     6361 caaaatgcga tagatattta caaagaagtg atagagcgca ttgagaaaga tgcagatgtt
     6421 ttaatgaaaa aatttaatat cactgaaaaa ggatttgtcg taaaccatct ttcgacagat
     6481 ttttctgatt cgcataaaaa agggagaaga gtattttgtg tggaatttgt atcgggagat
     6541 aaaattttat ataaaccacg aagtttgcaa aatgagatta agctacaaga gattacaaat
     6601 tatttctata gaatatgtaa tttgggaagt tatgagtatt ctatacttga taaagaaatg
     6661 tatggttggt gcgaaattgt aatacaaaga gattgtaagt ctatagaaga actttcaaga
     6721 tattatcaaa gaatagggat tattttgttt ataaattatc ttttggaagg aggagatatt
     6781 cattttgaaa atctcattgc atgcaatgaa tatccagtta ttattgatgc ggaaacattt
     6841 ataggaaata tagaagagaa taatgggaaa agtgcagcag aaaaagtggc tagtcttttg
     6901 agaaaatcgg tgttgtattc aggaatactc cccttttatt catggaataa cgcaggagat
     6961 acaggaatca atatgagtgc cattagtgga gaagaaggac aaaaattccc gataaaaatc
     7021 ccctttatta tcaatccgaa gtcggttaac atgagggttg tctatgatta tccagtatcg
     7081 aaaggaaatc acaatttggc aatgctaaaa ggaaggttta ttcaaccctc cgaatttgca
     7141 gataaaatta tccagggatt tgaaagtgca tacttaggtg caatggaaaa tacagaaaca
     7201 ctattaagaa tcatacaaca atatggtgaa ttagaggtga gatatctgat tagaaataca
     7261 caacagtatg caattgtgtt gagtagttca tatcatcctg aattattagt ggatggagga
     7321 gcacgaaatt tattttttta ttcattggca aatggaaatc ttcaaaatca aaggagtaga
     7381 tctcttattg agtatgaaat tgaagattta ttaagtggtg atataccgta tttttatttt
     7441 cgtggaagta aaaaaaacat ttatacttgg gatggcagag aagtaaagga tttctttagt
     7501 aagccagctt tgcagcaaat tgaggaaaat atacagaatt tgtcctataa gaatttagaa
     7561 caacagacgc aatatattaa aattactttt aatatggaga atgcaggaac aaggaaaata
     7621 aagaataaaa ggttaaaact agatctttat agtaatatgg ccaaaacggc agaagaattg
     7681 gcaaaagagc tgctagataa aataggaaca aatgcgattt atagcgaaga tggagcagac
     7741 gttaattgga ttggcgtaaa attatttggt ataaaagaaa atcagtggat gatccaggca
     7801 ttaccgaata cattatatga tggtacggtt gggattaatt tggtattcca tttatatgaa
     7861 tggatatacc atgacagaaa atatcataag atttgtgagg ttttagataa tcgtttgttg
     7921 aggtatattg atactataag tgaaggggaa cagaatatcg aagactttaa tacaggaatc
     7981 tttagcggcg aaggttcgat tttatatacg ttgggtattt tatatgaaat atatgatgat
     8041 atcaagtata aggaatattt cgataagtgg ctaaattgta tggaaacact tatcttagaa
     8101 gatcgtttgt tcgatatgat ttcgggaaat tcgggaatag ttttggttct gattaatatg
     8161 tatagaaaaa caaaaaagcc tatttatcta caaaaagcta tacaaatagc agaacaattg
     8221 atagagaata tgattactga aaatggaaaa gttggttgga aatcagaggt ggttcctgaa
     8281 gtattggcgg gatttgcaca tggaaacagt ggttttatag aactattttc aagattatat
     8341 gaggtatatc cacaaacaaa atatttagat atcctttcaa gtttagtaga atatgaaaat
     8401 tctttatact cagaaaagga taataattgg attgatttaa gaaagttttc agaggttgat
     8461 cagcataaga gtcaaccaat agcgtggtgc catggagctg cgggtattct gttatccaga
     8521 ttaaccttat ataatgccat caagaattta ggagaaactg cattgcttca gcaagctatt
     8581 aaagatataa gccttgctaa aaataaatta attgaagacg ggttacatgc aggtttctgc
     8641 ctatgccatg gaaacatggg aaatttattg attttaaaaa gatatgcaga aatttttgat
     8701 gataagcagg taagaagcat ttgtgattct cgatttgaac agattttgga attccttaat
     8761 gaggaaaata tattaccaac agaattatac aatccaggtt ttatgactgg tttatcagga
     8821 atcgcttatg ctttgttaaa atataagatg cccaaattac cattgcttat aggagttgag
     8881 ggaatatatg atagaaatga agtttagtaa aaatgatgaa gaagatgggt tgttccgcat
     8941 aagttcgaga gacatagttg gattttataa ttgtagtagt aaacaagagc gtaagataac
     9001 agacattata aaatgctatg gaacaacaaa aagcataaaa gaagttgaac tgaaaaacat
     9061 gaagccagag gataatgtta cagtatctcg gtatatagag agaaatgtag gttcaattat
     9121 aaacaaagat tatgtgattg aaggctttct gggaatgggg aagttgtccg attgtaaaga
     9181 cgaaatggtt agcagattgg atatatctaa gagatactgc ttagaaatat tagtggcatt
     9241 tcttcaagaa gcagacatta ttattttgca tgaaatgttt gaaaatgttt ggaatcatac
     9301 tatagaggaa attttagttg aattttcact aagaggagca gtggttgtgt tctcagaaca
     9361 tggtgaagaa tcattgatga aattaccaat gcacagttac gacctaagtg gtaggtgtgt
     9421 tggatggtag aataattggg gaatatgatt tttcatattc cttgagatat atagggtaga
     9481 aaatatattt agctgcaatg ttttgtccct ccatagttaa cgaatctatc taaataagaa
     9541 ataggttata tcaaacagat tttacaaagg agaaatacat ggagagagtt ttaataatat
     9601 cttatattat cagtatgata cttacggcag gctttattta ttgtatttat agagagaaat
     9661 attgggtttt tgaatttgta aacagaataa agaagccgat acagcaactt gtttatgttt
     9721 ttcttatgct cctatcatcg tatgcctata tatgcttttc gttactcata aaggctgatt
     9781 ttaatgctgt gatatgtgcg gtgctattac ttcttttgat ttgggctatg gactatctgt
     9841 tttctttatg ttttaaaaaa aatgatttgg ggataagtga aaaaaaacgc tatattttta
     9901 tggcgtatgt gggagcctgc atatcgggat ttattattgc aagtcgtgat gcttcgaaaa
     9961 tggctttaga aattccaaat ataacaatta gcgttttgat cggagcttat gtacctttta
    10021 cattattatt agaggatggg aaaaaaggga aagtagaatt gcaaagtatg aaagaagaat
    10081 gggaggaaaa gtataagaag acatttcgtg aacgtaaggt caaagacatt ctttctgctc
    10141 tactatttgc gatggtatat ggcgttttac tggtaggggc gttatctcct gctcaaaata
    10201 tcatcaatga tattgcttca gggataggaa tggggatggc tacagtggtt gttgcctttg
    10261 tagggttggt tgaagtgaaa aacaggttaa cgaaaaggag gaataaaaga gaagacgcag
    10321 atcaagagaa atccgataca gagtagaagg ggcaagacag caaggagtat ttagccggaa
    10381 ttatttcaaa tgtacctcac aagattggat gttgatgcga tataaatgat atgatatact
    10441 gaagtccata ttattagatt tgtggagaaa tagggatagc caagagaaaa aatataaaat
    10501 taaattttgc agaaagaagg catttttatg aaacttgtag gaagcagaaa attaacatgg
    10561 ggaatttgca gtattggtgt tttattagca atagtaagcg tgtttttctt acctcagatt
    10621 attcctgttc attttgcaaa tgggatagca gatgattttg gaaataaggt agagattttt
    10681 ttatttccta ttttgttaat cataattaca cttttgactg gaaaagaaaa cattaaatat
    10741 ttcctgacac attcaaaaac atttttgaca gatatacagt ataatttgat gatagatggc
    10801 gttctcggaa ttgttttgat tgcagaaatt tatgttattt atgcttcatt tgtttaagtg
    10861 tttcaacaaa aaattccagt ttctataaag agcaaaggag aatggtcatg attgatatgc
    10921 agaatcaaga ggaaattccg atcttagagg attttgcggc atatattaga aatccagtat
    10981 ttatgaaatt ttgttccgag attaaaaaga agtacaggtg ccatgaaaaa atagaattta
    11041 gccgttgtag tttagaacgt ggttggaatg taaaatttaa aaagtctggg aaaagcctgt
    11101 gtacgatata tccaagagaa gggtatttca cagtgctggt tgtgattggt tcaaaagtaa
    11161 aagaagcagt tgagaatatt ttatgcgact gtgccccaga attaagagaa ctttatgaaa
    11221 aaacaagatg gggaaatgga caaaaatggc ttatgattga tttagaagat caaggagaaa
    11281 tgtttgcgga tgtacttcag cttattgaaa ttcgcagggg ataatcaatt ttggagtgtg
    11341 gaacaaggag taaagacgga agactgcgag gtaaacgatg aagacgtatg aaaataaaga
    11401 ggaactaaag gcagaaatca agagggctta cgacaaatat attgcagagt ttaaggatat
    11461 cccggaatcc ttgaaggaca aacaatgtat ggaggtagat cgaacacctg cagaaaatct
    11521 tgcatatcag gttgggtgga ccgcattagt attgaaatgg gaaaatgatg aacaggctgg
    11581 acttccagtg aaaacaccat cggatggttt taagtggaat caattggggg aattgtatca
    11641 gtggtttacc gatacctatg cccatttatc tctaaaagaa ctaatgggca tgctggatga
    11701 taatatacag aaaattttta caatgattga ttctatgacg gaagaggagc tatttttacc
    11761 acataaaaga aagtgggcag atgaagctac caaaacagca gtatgggaag tttataagtt
    11821 tattcatgta aatacagtag ccccttttgg aacatttcgg acaaagatta ggaagtggaa
    11881 gaagctttta ctttgacaca cagatagagt tttagaaaat atcgtgcttt tttgtgcaaa
    11941 agaaaataaa tatataatgc tatttggagt gcatattcag tttcaggata tgcacttttt
    12001 taataaaata aaagagacaa acattattca gattcaaagg gtaagaaatt gtgataaatc
    12061 tatacggtat gctttaatgg ttttggaatt taactttttt atggtttcac atgttttgag
    12121 atattcggat ataaaatttg ataattgatc cataataggc accctccttt gtttttttca
    12181 attatgagtg cctatatgga aaatgtcgat tttattttgg gaaaaactta tttaaagttt
    12241 ccagtgtccc ctttgcagaa aatccccata gtatgctgct aagagcgtta atagcagcct
    12301 gcctccttcg gtagtacgtc cggtaggaga tactgggaac gtgcttttcc aactcttcca
    12361 ggatttcctc tgtatttttc agttcatggg gagacagaaa ggcgtaatat aatatccagt
    12421 aatattcttc cccatgctta tgatttttcc ggagcagatc cacagaagag agaagcagct
    12481 ttatcatttt gttactgcgg gcaatgcttt ttgcccattc ttcaatctgg ctgtctccca
    12541 gatctgctcc tgcagcatag atggaatcta gaaattcgtc tacactggtg ttgtattcca
    12601 gttggaattg aatttccacc tgccggacag caaccatcag gctataagta gaatcccggt
    12661 aacaacggag cagcttatag gtatcatggt acaacggatt attttctact tcagcagaaa
    12721 cagggtggtg atttttcttt gccattatac aacccctcct ttcaacagaa cttctgggat
    12781 ttcagcgaag gcaggtaagg tatgctgcag aggcggagta tgccctggga cgttggtgac
    12841 ggcgtgattt tccggtttta gttttaattc aaactgatag gctgctttcc cccaggggca
    12901 gataatacgt agtgaatata gatatatact atccttgcag gctgataaag gagataatat
    12961 atactttgtt ttggggcatc tacaacaaga aatgccttgt atttccagta tttcagcgac
    13021 tttgcgaaca atgactttga tgtgtgattc tggaacgcag gagccttcct gtgaaacgat
    13081 gatttgttcg tcagtaatag attctgaaac gcattcagaa ttgtttttgt caggcaaggt
    13141 atcttcggtt atatgtattg gcagttgcat tttcatggca atttcctcct tatcaatcat
    13201 gacatcactg atattaaaca taacggacag ataattacgc agatatacca tgctaccatg
    13261 tttcccggaa taggaaatca gtgtgatcat gtcggtatct tcaagttttt taagcagacg
    13321 ggatacagaa gatttcgact gtttccaacg tctggcaagt tcctgataac tgaacaaggg
    13381 atttccagtc tgattgcgaa aatatactac tggaccggca tcagagcctt gcacagatgg
    13441 atcattatag actgcatgaa tccaaagatc caaaagagca tccatttctg aacattttcc
    13501 cagtccgatt agtttatgaa catctgcgat tggaaaaaag aaaaacccga tgtctttttt
    13561 gcatgggtaa ttataggaaa gggcagtatt atcttttggc cagtctttga tcttgtattg
    13621 gataatctta tttttttcgt gcagtgagta ggttaaaagg ttttgctcaa ccagggtatc
    13681 caatatggat atgacctggt gctggaattt ttggcggaag tgaatctgga gttctttaag
    13741 agaacagatc cattcgccag gaacaacttt gtaagtaagg tgttcgatgt tccgataaga
    13801 ggagctgtaa tttgcataag aacataaaat gagaaaataa aaaagacagg aacctccgtt
    13861 ggtacggatg cttctgtctt tcataagggt ttgtataaat tcccggtaaa tccggcagcg
    13921 tggaaaatcc acaatttgtt ttaattctaa ttgataattc acgataaacc tccatataat
    13981 attgtagttg tagtaaaata attgtagacg aaagatacta aaatgtatat aatatgccca
    14041 taggggtgct aagtggcata gatttggcac agtaaaatac ctgatatggc atgaaagcaa
    14101 catgaaaatt agggtggata taaggtggac agtttggaaa accttagagt tttagagggt
    14161 tccgaggttt ttttccgggg tctgcaacac ctctatcacc agttcaaatc tggttggcgc
    14221 ctctaggaga aatctggaaa caattgtttc cagatttttt ggtatacaaa tataatatac
    14281 catatataaa aatgcggtat gtgaagaatg tgcttcctac atcaaaaaat aacagaaaat
    14341 atattgaaaa tcagctttcg ggagccattg agcagatgga agaatatatc agaaagtatc
    14401 cgatgtttct tgttatggat tatgtgtaaa actatagatt attataataa ttaaaatatt
    14461 gtttcgtcat cttgaatatg ctatacttga attatgttta taggggcaaa gctgttgaaa
    14521 aactgtgacg caaagccaaa gggactaagg cagtacgcta tgtcagccgg ttgcaataag
    14581 aagatgcgga taggttaata gagtaagtga aaaaagttat tcggcttaaa ttttagtcac
    14641 ctgtataacg caggtgactt ttttgtttca taggaaatta cattttctat gtagaaaagc
    14701 ttccggaaga atgcatagga gatgagggaa atgaaaaaag gaaagaaatg gaaaaaaatt
    14761 gaagcattct gcattttgct cattgtgaca ttgttgctta tttttgtcag aatactgtat
    14821 cagccgggta cggagtcgga aaggggcgag ttgtacacct tcagcaatgg atggtatcag
    14881 ctgaaggatg ggaaaaagac ggagctcaaa ttgccatgtt ttgttacagc ggataaagat
    14941 gggcagatca ttctttacaa tgatatgtta tcagaggctg ataagggaaa aatcttgtcg
    15001 atccgaggaa tacaggatca gctggaagtc tgcataggag accggcttct ctaccaatat
    15061 aaggataaca gatttgaaaa aaacaggcag atgaaaggga aaatatgggc agatatttct
    15121 ttgccggaga aaatcgggca ggaagtgtta tcaatcagct atgaaactaa aaagaatgcc
    15181 agactatatg tgtatgcccc gatgatcgga gagttttgtt ctgttttcag acagcatctg
    15241 ctagaatcaa ttttttcgat actgatgatt ttgggaatga ctggtctcgg tatcgtctcg
    15301 gtaattgtct ttttatatac cagacacaga caaattgtag aaaagagatt tttaaatgta
    15361 gcactgtttt tgattctatg cagtttgtgg tgcatttttg attcaggaat ttatcagatg
    15421 tatggaagtc agaacgcagc aggaacactg atatcctttt atgcgtttat gacgatgcct
    15481 gttcccatgc tgttatttgt acaaaataca gtgagtgaaa gtgtaagagg gataccgcag
    15541 gtctggattt ttcttcttta tgcaaatgct gttttacagg ggattctgca tcttctgttt
    15601 aagattcctt ttatacatat gttatatatc acacatctct tattgtttac gggggttgtg
    15661 tctatgatcc ttcttttgtg gaaagagtat cggaaaacgc aggagaagga agtaaatctc
    15721 tgtctaaagg catttggtgt attagggata agcggtgtaa tcgcactggt actgtactgg
    15781 gtattatcca tttactggta tgaatctatt ttccagtttg gcattcttct ttatattgct
    15841 gttttgtttt ggggattgct ttgtaaagta tccaacaaca ttcagttttg cctggaacag
    15901 gaggtttata ggagaatgtc cttggaagac cggatgacag atatgaaaaa ccggaaatca
    15961 tttgagatgt atcttgaaga gatccaggag ggtgcgattt tacttgaaaa tgtattattg
    16021 ttgtttgtta aaattgcaga actgaagaag attaatgata tgtctggaag acagatgggt
    16081 gatgaaacgg ttatccgaac ggcaagaagc atccagagtg cagaaaggag tgttctggaa
    16141 cagcaggcgg taagttttcg tgttgaaggt gatgagtttg cgattatcgt aaaaaatccg
    16201 caaaagacac cggaagaatg ggagcatttt ataaaagaag agatggaaga agaatgtgga
    16261 aacagacagc ctgtgcggct gaagttcggg tatagttatc tgagagaaaa gaatggtagt
    16321 cttctttcat tcagtgactg gaaacagcag gcagacgata tgctttgttc aaataaataa
    16381 aaaccggcgg aggataaata tgacttataa tatagatttt cttattgcgg caatggttat
    16441 attgttgctg gttttatggt attttctggg acagaaaaga gcagaggatc tgaataatca
    16501 ggtattcctt ttctttgcca tcatcggtat tttagatgtg gttgcggaac ttgccagtaa
    16561 ttattatatt tcttttccaa atagtaattg tgaaattgct gcaatgcttg caacaacgat
    16621 cttttatctg cttcaggcat tgctgccgtt tacggtgatc tgttatattc agacattaca
    16681 tgataataag atcatttcgg caaaaaagat gtttttatca ggtgtgccga cattcattct
    16741 gatggggatg attctgacaa acccgttcac agaaaagctg ttttattttg atataccggc
    16801 aggctatatg aaaggtccat ggtatatgct gatgtattac agtgcacttt gtcatatggc
    16861 agcagccttg atccttattg tcatatggcg gaaaaaactg ggctatcaaa aagtgaagag
    16921 cctgctggaa atcctgttga tatccggtgc gggagtggtg atccagcttt tatatcatcc
    16981 gcttcttaca acagggtttg gtatgagtct gggaattctg gtactattta ttacgatcaa
    17041 caatcctcat gcaaatatcg atacacttac cggattatat aatcatctgt atctggtcag
    17101 aaaaagcaat gagctgatca gtgcgggaaa atcatttcac attattacgg tgtatcttta
    17161 tcaattgaag cacattaata aaatcgcagg ggtacagggc ggtaattcaa tcttaaagct
    17221 gacagcaaga aaacttggtg agatgtgcgg gaaaaaagca tttcgtacaa cgggaaagag
    17281 ttttatgata ctcaccggtt cacttgaaga atatgaatat tatcttacgc agctgaagag
    17341 aatgtttgat ggaaacagta agctgaatgt caacaataaa attattacga tgcctgtgat
    17401 cataagcggg atcatgaatg cgcagaaact cggagacagt gggcttattc tagaatatgc
    17461 tgaatatctg gaagccttat ctgcgaaaaa tggtctgaca gaggtgatac aggatgatta
    17521 tcagacgatg aatggtttcc tttataataa acgggtagaa cagtatttgc ataaggcgat
    17581 tacagaggat ctgttcgaga tatactatca gccggtttac tctacacaga aaaaatgctt
    17641 tatcacactg gaagcgctaa gtcgccttca acatccggag cttggctgga tcgcaccaga
    17701 tgtatttatt cagattgcag aaaaaaatca tatgatcgaa cagatcacag atctacagtt
    17761 tagtcgtgtc tgcagatttt taggagaaaa ccgatacctg atgaggcatc ttctgaatgt
    17821 aaaagtgaac ctgtcttctc tggatctgat gagaaatgac tgtagcagac attttatccg
    17881 gattatggat gcttataaga ttccacataa ctggatacag tttgaaatca cggaaacggt
    17941 tgcgactgaa tgcaatgcgg gtctaagaag agttgcggag gaatttacgg ccgctggcat
    18001 tggtttgtgt ctggatgatt ttggttccgg atatgcgaat ctgaatacgg taatgaggct
    18061 tccgttttct gtgatcaagg ttgacagatc tctgcttttt gatatctgca gggatgagaa
    18121 acgggcaatt ttctatgaaa gtgttgtaga aacatttcat aaaatgaatt atcatattgt
    18181 ttccgaaggg gtggaaacac aggaagaaat ggaacagatc agcagctggg gagtcgagat
    18241 gattcagggc tattattttt ccaagccgct tcctgaaaaa gagcttttgg aattgctgaa
    18301 gaagcaggat aatatagaaa gataaaatta agagggaagg gagatagtag atacacatgg
    18361 ggacatccga ttgcggaggc aattcatcag gcagacaaat taatgtatga aaataaaaga
    18421 atgtcataaa gaggaggaaa gaaatgttac ttattaaaaa tgcaaaagtt tatgcaccgg
    18481 agtatgttgg aaaaaaggat cttttagtat gtgggggaaa aattgaatgc atggaagata
    18541 agatcgagga ttttccaatc gcatgtgaag ttattgatgc agaggaaaga attcttacac
    18601 cggggtttat tgatcagcat gttcatgtta ccggaggcgg tggggaagga agctttcata
    18661 cccgtacacc ggaacttcag ctgtcagaac tggtaaaagg cggaattaca acggttgtag
    18721 gacttcttgg aacggatgga cttacaagga gtgttgaaaa tctttacgca aaagtacagg
    18781 ctttatgcga agaaggggta agtgcgtata tgcttaccgg tgcatatgga tatccaagtc
    18841 cgactattac cggagaggta gatcgggata ttatgtttgt tgaaaaagta cttggcgtga
    18901 aacttgc
//
