LOCUS       NZ_JAQCYD010000003     18946 bp    DNA     linear   CON 23-FEB-2024
DEFINITION  Streptococcus mutans strain AF36-21BH AF36-21BH.Scaf3, whole genome
            shotgun sequence.
ACCESSION   NZ_JAQCYD010000003
VERSION     NZ_JAQCYD010000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptococcus mutans
  ORGANISM  Streptococcus mutans
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 218156)
  AUTHORS   Lin,X., Hu,T., Chen,J., Liang,H., Zhou,J., Wu,Z., Ye,C., Jin,X.,
            Xu,X., Zhang,W., Jing,X., Yang,T., Wang,J., Yang,H., Kristiansen,K.,
            Xiao,L. and Zou,Y.
  TITLE     The genomic landscape of reference genomes of cultivated human gut
            bacteria
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 218156)
  AUTHORS   Zou,Y., Lin,X. and Hu,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-NOV-2022) BGI Reaserch, BGI-Shenzhen, Beishan
            Industrial Zone, Shenzhen 518083, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. v2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100x
            Sequencing Technology             :: MGI
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/23/2024 01:23:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,988
            CDSs (total)                      :: 1,943
            Genes (coding)                    :: 1,890
            CDSs (with protein)               :: 1,890
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 33 of 53
            Pseudo Genes (incomplete)         :: 28 of 53
            Pseudo Genes (internal stop)      :: 23 of 53
            Pseudo Genes (multiple problems)  :: 22 of 53
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:29:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 108533
            Orig. end                         :: 127479
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAQCYD010000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..18946
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..18946
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..18946
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:13946](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..13946)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            959..1327
                     /locus_tag="PGX70_RS05290"
     CDS             959..1327
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264180.1"
                     /locus_tag="PGX70_RS05290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF956 family protein"
                     /protein_id="WP_002263350.1"
                     /transl_table=11
                     /translation="MAQSINTKVEYTGKGVSYLGVGGKVGKFLLGDRSFEFYNDANVEH
                     FIQIPWSSIIEIGANVNRKKVSRHFEIITDKGKFLFASSDSGKILKIARQHVGNDKVVR
                     YPSLLQKIASFFKRKKKG"
     gene            complement(1564..2637)
                     /locus_tag="PGX70_RS05295"
     CDS             complement(1564..2637)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019314203.1"
                     /locus_tag="PGX70_RS05295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyltransferase"
                     /protein_id="WP_226711742.1"
                     /transl_table=11
                     /translation="MNKKNEKIKSLPYNTGIDFLRIFAMFMIVVTHVLGKGGIRSTVKE
                     NFDLYYFVTWGIQVSAYSAVNCYALISGYVGVDSPYRYSKCLSLWLQVFFYTLLFILFF
                     TFLQKPITYHDWIQAFFPIITGQYWYVTAYFGLLIFMPILNLALRKLNTKDLKRIVLLA
                     IIFFSILPALLNTKVDEFSFAKGFSMNWLSVLYIIGAYLKRLDLKRLFSRKFLLFLCLM
                     AMAVTFITKVFIGDIWYWYTSPTLLCEAVTIFIFFVTLDIKKTGRLFRIIKRMAPATLG
                     VYLFHLNPLLVKFLLKDGFESFVTAPIWLFPFLILGMALLIYLISTLVELLRIKLFTYL
                     KVRHLILKLDTYLPFDN"
     misc_feature    2673..2684
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: strong, score: 19.35"
                     /tool="antismash"
     misc_feature    2680..2694
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: medium, score: 24.91"
                     /tool="antismash"
     misc_feature    complement(2964..2978)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 23.18"
                     /tool="antismash"
     misc_feature    3096..3109
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.0"
                     /tool="antismash"
     gene            3161..4435
                     /gene="serS"
                     /locus_tag="PGX70_RS05300"
     CDS             3161..4435
                     /EC_number="6.1.1.11"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="serS"
                     /gene_functions="other (smcogs) SMCOG1162: threonyl-tRNA
                     synthetase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002271339.1"
                     /locus_tag="PGX70_RS05300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="serine--tRNA ligase"
                     /protein_id="WP_002271339.1"
                     /transl_table=11
                     /translation="MLDIKRIRNDFDQIAEKLARRGVDEKTLHDLKELDFKRRQLLIKS
                     EEAKAERNTASAAIAQAKRNQEDASEQIADMQKLSAEIKALDAQLVEIDGQLKTFTTTL
                     PNIPADDVPLGADEDENVEMRRWGKPRQFDFDIKAHWDLGEDLDILDWERGSKVTGSRF
                     LFYKGLGARLERAIYNFMLDEHAKEGYTEVIPPYMVNHDSMFGTGQYPKFKEDTFELAD
                     NDYVLIPTAEVPLTNYYRGEIIDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIRLHQFH
                     KVEMVKFAKPEDSYNELEKMTANAENILQKLELPYRVITLCTGDMGFSAAKTYDLEVWI
                     PAQNTYREISSCSNTEDFQARRAQIRYRDEVDGKVKLLHTLNGSGLAVGRTVAAILENY
                     QNADGSVTIPEVLRPYMGGTEMIVP"
     gene            complement(5001..5270)
                     /locus_tag="PGX70_RS05305"
     CDS             complement(5001..5270)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002278332.1"
                     /locus_tag="PGX70_RS05305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_002278332.1"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 7.4e-11,
                     bitscore: 36.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTQTLEHFDVLDADLLAKVQGGDWQCTSGVLGGMVYGALTGAGA
                     GAAIGAAVSAPAAEGGGVGPAAGALLGGTYGAIGGILQGATACE"
     gene            complement(5303..5575)
                     /locus_tag="PGX70_RS05310"
     CDS             complement(5303..5575)
                     /GO_process="GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002279082.1"
                     /locus_tag="PGX70_RS05310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Blp family class II bacteriocin"
                     /protein_id="WP_014835037.1"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 8.4e-11,
                     bitscore: 35.9, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTQTLEHFDVLDADLLATVVGGVNQCFAGTTGKVIEGALAGGAA
                     GATIAAAVSAPVAEGGGIGPAAGAGIGAVLGGISNGLYGASQYCN"
     gene            complement(6020..6399)
                     /locus_tag="PGX70_RS05315"
                     /pseudo=""
     CDS             complement(6020..6399)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002943526.1"
                     /locus_tag="PGX70_RS05315"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRRKSSFIICIAIIIISNILMMTVINNGEEKLSNLFVIAIALVCF
                     PGFLWAIDNEMISLIRIESSALLLLAVLSAMRLINRLTPYLLW"
     gene            complement(6427..6627)
                     /locus_tag="PGX70_RS05320"
     CDS             complement(6427..6627)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002274099.1"
                     /locus_tag="PGX70_RS05320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_002271336.1"
                     /transl_table=11
                     /translation="MLAGIEVEGGVNWERVFAGATVYGDATMAVCMATGPIGWGVGAAY
                     LTTCAASGAYIMVWQPNLGIG"
     misc_feature    complement(6597..6606)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 17.05"
                     /tool="antismash"
     misc_feature    complement(6666..6680)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.99"
                     /tool="antismash"
     misc_feature    6667..6680
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.01"
                     /tool="antismash"
     gene            complement(7412..8440)
                     /locus_tag="PGX70_RS05325"
     CDS             complement(7412..8440)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288905.1"
                     /locus_tag="PGX70_RS05325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thiol reductase thioredoxin"
                     /protein_id="WP_002299839.1"
                     /transl_table=11
                     /translation="MKYYKTLLLCSASLLLLAAGVAYAEEETPQGIEKTEVSAPAVTTE
                     TQSADVTVVQETVAPAATTASTVTSSENKSKRSDENSVRETSLETSDQVIENSQPPQQE
                     VDTSSSTEKISDSKNTVSEGVSVEEYEANVANFKAVSMADVYHMFDDSENDYILYIGRP
                     TCHYCRDFSPVLKEFNGLTGSQLYYYNTDRDDFTVAAKEFLTKKVGMFATPTTLYIDKG
                     QLISGWVGSGITAQNLYNKLYSHTIQKKEYESENNGIAPAEAPNTDKENTKVTDEKVTA
                     VPGSGEPAPNQKRGETPDPIAKKSDFSQTIADKTSKKSLTLNKIITQILSLIRDALLKL
                     NI"
     gene            complement(8925..9113)
                     /locus_tag="PGX70_RS05330"
     CDS             complement(8925..9113)
                     /GO_process="GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263743.1"
                     /locus_tag="PGX70_RS05330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Blp family class II bacteriocin"
                     /protein_id="WP_002270918.1"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.9e-10,
                     bitscore: 34.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKQYNNFKILNTDALENIQGGGRDPRCAALVGASIYDGLAVVGG
                     PVGVAMTAGTIAAGSFC"
     gene            complement(9277..9489)
                     /locus_tag="PGX70_RS05335"
     CDS             complement(9277..9489)
                     /GO_process="GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264173.1"
                     /locus_tag="PGX70_RS05335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Blp family class II bacteriocin"
                     /protein_id="WP_002264173.1"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 5.3e-12,
                     bitscore: 39.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTHVLEQFDVMDSQVPSAIEGGGCSWKGADKAGFSGGVGGLIGA
                     GGNPVGGVLGIAGGLDAYGELVGGN"
     gene            complement(9894..10058)
                     /locus_tag="PGX70_RS05340"
     CDS             complement(9894..10058)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019320588.1"
                     /locus_tag="PGX70_RS05340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_270513798.1"
                     /transl_table=11
                     /translation="MKKYLVVPFALIIIFLGVKVLLTSNNIWQMMFASIGMLLFLFGVF
                     REYSKIKIK"
     misc_feature    10489..10498
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     gene            10498..>10710
                     /locus_tag="PGX70_RS05345"
                     /pseudo=""
     CDS             10498..>10710
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611514.1"
                     /locus_tag="PGX70_RS05345"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKLTYENKLKIYELRKNGMSWSQLNQKCGVSLSNLKYMVKLMDPY
                     DLERVRKGNNIYLSPELKQEMIDTLL"
     gene            complement(10833..11237)
                     /locus_tag="PGX70_RS05350"
     CDS             complement(10833..11237)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002274065.1"
                     /locus_tag="PGX70_RS05350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_002263912.1"
                     /transl_table=11
                     /translation="MRLSKCSSRVLRFLRLGAVLSGFLALDLCFHMIDSKSSIWLWLPL
                     GILSLLVFLVAYLAYKELNQRPIAEQQFTQYQTQTAVTIFSFLVLLVCSYRAITTNDTT
                     QRTALIIVNILLVIVIIWNLIELIKLHKRR"
     gene            complement(11384..11803)
                     /locus_tag="PGX70_RS05355"
     CDS             complement(11384..11803)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002279873.1"
                     /locus_tag="PGX70_RS05355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_002263913.1"
                     /transl_table=11
                     /translation="MKKSKQKAKITYSREKRKVAVAVTCIFIGLIIMKGYISIKRGIQF
                     VASNLTFVFILFFCLLAEWISRKMKKEDQSVKAARICEKRKTVIIYTFGLMVMVILNVY
                     ASITKQAHFMDINLILMFLIVLGSLIDWVIEKIKK"
     gene            complement(13184..13585)
                     /locus_tag="PGX70_RS05360"
     CDS             complement(13184..13585)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310604.1"
                     /locus_tag="PGX70_RS05360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_002310604.1"
                     /transl_table=11
                     /translation="MFKKESQKLRLLRLLTAQLIAVCLLILVLTQAIFKSPLLVQICFV
                     IITFCTAGLNYYFIKEIREVNSQESSAATITSQVVLTAVFFLLTVLSSYKTIQVSEFAS
                     RIIFLIAAVISFIISLLLLWGIKYVKKTQ"
     gene            complement(13716..13946)
                     /locus_tag="PGX70_RS05365"
     CDS             complement(13716..13946)
                     /GO_process="GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019805678.1"
                     /locus_tag="PGX70_RS05365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Blp family class II bacteriocin"
                     /protein_id="WP_002265368.1"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 7.2e-17,
                     bitscore: 55.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTQAFEQFNVMDNEALSAVEGGGRGWNCAAGIALGAGQGYMATA
                     GGTAFLGPYAIGTGAFGAIAGGIGGALNSCG"
     gene            14213..14353
                     /locus_tag="PGX70_RS05370"
     CDS             14213..14353
                     /GO_function="GO:0005186 - pheromone activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012997567.1"
                     /locus_tag="PGX70_RS05370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="WP_002270250.1"
                     /transl_table=11
                     /translation="MKKTPSLKNDFKEIKTDELEIIIGGSGSLSTFFRLFNRSFTQALG
                     K"
     gene            complement(14495..15820)
                     /locus_tag="PGX70_RS05375"
     CDS             complement(14495..15820)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262113.1"
                     /locus_tag="PGX70_RS05375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GHKL domain-containing protein"
                     /protein_id="WP_002267940.1"
                     /transl_table=11
                     /translation="MNEALMILSNGLLTYLTVLFLLFLFSKVSNVTLSKKELTLFSISN
                     FLIMIAVTMVNVNLFYPAEPLYFIVLSIYLNRQNSLSLNIFYGLLPVASSDLFRRAIIF
                     FILDGNQGIVMDSSIITTYMIEFAGIALSYLFLSVFNVDIGRLKDSLTKMKVKKRLIPM
                     NITMLLYYLLIQALYIIESYNVIPTLKFRKFVVIVYLILFLILISFLSQYTKQKVQNEI
                     MAQKEAQIRNITQYSQQIESLYKDIRSFRHDYLNILTSLRLGIENKDLASIEKIYHQIL
                     EKTGHQLQDTRYNIGHLANIQNDAVKGILSAKILEAQNKKIAVNVEVSGKIQLPDMELL
                     DFITILSILCDNAIEAALESLKPEIQLAFFKKNGSIVFIIQNSSKEKQIDVSKIFKENY
                     STKGSNRGIGLAKVNHILEHYPKTSLQTSSHHHLFKQLLIMK"
     gene            complement(15817..16569)
                     /locus_tag="PGX70_RS05380"
     CDS             complement(15817..16569)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012997565.1"
                     /locus_tag="PGX70_RS05380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_002267939.1"
                     /transl_table=11
                     /translation="MISIFVLEDDFLQQGRLETTIAAIMKEKNWSYKELTIFGKPQQLI
                     DTIPEKGSHQIFFLDIEIKKEEKKGLEVANQIRQHNPSAVIVFVTTHSEFMPLTFQYQV
                     SALDFIDKSLNPEEFSHRIESALYYAMENSQKNGQSEELFIFHSSEIQFQVPFAEILYF
                     ETSSTAHKLCLYTYDERIEFYGSMTNIVKMDKRLFQCHRSFIVNPANITRIDRKKRLAY
                     FRNNKSCLISRTKLTKLRAVIADQRRAK"
     gene            complement(17040..17678)
                     /locus_tag="PGX70_RS05385"
     CDS             complement(17040..17678)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1188: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302658.1"
                     /locus_tag="PGX70_RS05385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="VTT domain-containing protein"
                     /protein_id="WP_002267938.1"
                     /transl_table=11
                     /translation="MFFIDFILHIDNYIYSIANTVGLWTYLILFLVIFVETGVVILPFL
                     PGDSLLFAAGALAANPKMHFSVLVFGILFFIAAFVGDTCNFFIGRTAGYRLVHHKFFSQ
                     FIKEDNIKDAELYFEKYGSTSIILGRYIPIIRTFVPFVAGLSQFPVSSFIKRSFIAALS
                     WTVIATGAGYLFGNIPFVKTHFSAIILAIVFVTLLPSAITVVKTSKKKK"
     gene            complement(17726..18352)
                     /locus_tag="PGX70_RS05390"
     CDS             complement(17726..18352)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014677755.1"
                     /locus_tag="PGX70_RS05390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_002268642.1"
                     /transl_table=11
                     /translation="MFENLKAYLTQQGFKYIKPEKAGSLAEEMIALKTLGQSARAEFTE
                     IAKVLALKVSPFEMMRVSNWANQAQVARPHFWCYYKQPEDNQDDVGLAIRLYGNSANFG
                     ISVEVSFIERKKSKATLAKQHKVLDIPIAEPLYYFAQEKSESHRVSGTEAYRQMLRQKV
                     ADGQVRKVLVKYDIPISEGSDLVILTDQLAQGFDKLMPYYQATKL"
ORIGIN
        1 aagtcggtat gatgggacct ttggcaggtg ttggtgaccc tgttttctgg ttcacagtac
       61 gtccaatttt aggtgctctt ggagcttctc ttgctcaagc aggcaatatt atgggaccta
      121 tcattttctt ccttggctgg aatatcattc gtatggcctt cttgtggtac acacaagagt
      181 ttggttataa ggcaggatct gaaattacta aagacttgtc aggtggtatc ctcaaagata
      241 ttaccaaagg agcttctatc cttgggatgt ttattttagc agccttggta gaacgctggg
      301 tagttattaa atttactctc gcattaccag caacaaaact aacaaatgat aatggtcaaa
      361 ccttcgttgc acttcctaag ggaagcgtta gcggagataa attaaaagaa gctatcgaag
      421 gctttaaaaa cggtcttaac cttggtccag tcaaggtcga cagtcttcaa agtcagctcg
      481 atgctcttat tccaggtctc atgggattac ttttaacttt cttatgtatg tggctgctta
      541 agaaaaaagt ttctccaatc actattatca tcggtctctt tatcgttggt attgtcgctc
      601 acgttatcgg cttgatgtaa gcatcacatt cctaactaga taaaatcctc taaagttaat
      661 aaactttaga ggattttcct tagactattt aattattctt taaactaaaa aaattgtcaa
      721 ctgtaaaaac aaggcactgc tagataagtt caataaaata gtaatatgct ttgaaaaact
      781 catgataggg cgctgtgttg atgaggctag tttcgctcct tctatctccc acctcaaaag
      841 cttctccttg gactagccgt aatttagcga tacaagctag ttaggaaacg ccaaataaca
      901 aatagcacag tcctccgttt tttgatataa taaaatatat ttattcagga gtaaatttat
      961 ggcacagtca attaatacaa aagttgaata cacaggcaaa ggtgtatcat atttaggcgt
     1021 aggtggcaaa gtgggaaaat ttcttcttgg cgatcgtagc tttgaattct ataacgatgc
     1081 taatgtggaa cattttatcc aaattccttg gtctagtatt attgaaatag gagccaatgt
     1141 caatcgaaaa aaagtcagca gacactttga aattattacg gacaaaggaa aattcctctt
     1201 tgcctcatct gattctggta aaattctaaa aattgcaaga cagcatgttg gtaatgataa
     1261 agtggttcgc taccctagtt tacttcaaaa gattgctagc ttctttaaac gaaaaaagaa
     1321 gggttagagt aagaaaatgt agaatgttaa gttagaccaa tcatctaaca gcacatcctg
     1381 tttcaatatt ctaacctttt ttcttcagct ttttttgtta ttttaattgc aaatcgaaaa
     1441 gatctagtca attttctcta taaattctca taggatatgc tggaaagaaa tcatattcag
     1501 cagtttctag acaacttcat caaaatcaaa ctgttatcaa gataaaaaag gtcattaggc
     1561 cttttaattg tcaaacggca gataagtatc caatttaaga ataaggtgtc tgaccttaag
     1621 ataagtaaaa agttttatcc gtaaaagctc aactagagtc gaaatgagat aaataaggag
     1681 cgccatccct aaaatcaaaa aaggaaaaag ccatatagga gcagtcacaa atgactcaaa
     1741 accatctttt aaaagaaatt taaccaaaag gggatttaga tgaaaaagat aaactcctaa
     1801 tgttgccggc gccattcgtt taattattct aaacaatcta ccagtctttt taatatctaa
     1861 agtgacaaaa aagataaaaa tagtcactgc ctcacaaaga agagtgggag aggtatacca
     1921 gtaccagata tctccaataa atactttggt tataaaagtc actgccattg ccattaaaca
     1981 cagaaaaagt aaaaatttac gactgaataa acgctttaag tcaagccgct tcaaataagc
     2041 tccaataatg tacagtacac tcaaccagtt catactaaaa cccttagcaa atgaaaattc
     2101 atctactttg gtattcaata atgcaggaag aatagaaaag aagatgatcg ctaaaaggac
     2161 aatacgtttc aaatctttag tattcaactt tcttaaagct aaattcaaaa taggcataaa
     2221 aatcaagagt ccaaaataag ctgttacata ccaatattga cctgtgataa tagggaagaa
     2281 agcctgtatc caatcatggt atgttatagg cttttgcaaa aaagtaaaaa ataagataaa
     2341 taataaagta tagaagaaga cctgtaacca caatgagaga cattttgaat aacgataagg
     2401 tgaatcaaca ccaacgtaac cactaatcaa agcatagcaa ttaaccgcac tataggcaga
     2461 tacttgaatt ccccatgtca caaaataata aaggtcaaaa ttctctttta cagttgagcg
     2521 aatgccgcct ttccccaaaa catgcgtcac cacaatcata aacatggcaa aaatacgtaa
     2581 gaaatctatt ccagtattat atggtaaact ttttattttt tcattcttct tattcataat
     2641 gctttatttt aacataggaa aaaagtgagt gggaaaatgt tttcattttg agaaactttg
     2701 ttaattgtct ttcataaact gaaattttcc aatatcattt tttaaacaat ctttatttac
     2761 attctttttt aaatcctgta taataagaac aacggataag taggtccttt tcttttgcag
     2821 aaagtctgcg gcagctgcga gcagatagag tgattgaccg aaattctacc gttatagatg
     2881 attccatcca gtttccaaga ctgaatgaga caatctttat taaatgatta tcgtaattaa
     2941 gagcacagtc attgtgaagc tggatggaac cgcgcccaag cgctccagca agaacatgtc
     3001 tgtgtttttt ataaaatata gaaaggaagg tttggttagg taaaaaagtt aactgaacct
     3061 gccctataag ctgtgcaaaa aatagttttt cctagaaaac aaacgttcat tgtcaaaatt
     3121 cctatttttg ctttgctttt ttgggcttgg tatcttattt atgttagaca ttaaacgcat
     3181 tcgtaatgat tttgatcaaa ttgctgaaaa attggcaaga cgtggggttg atgaaaagac
     3241 actacacgat ttgaaagaac tggattttaa acgtcgccaa ctgcttatca aatcagaaga
     3301 agctaaagct gaacgcaata ctgcttctgc agctatcgct caagctaagc gtaatcaaga
     3361 agatgcatca gagcagattg ctgatatgca aaaattatct gccgaaatca aagcacttga
     3421 tgcccaatta gtcgaaattg atgggcaact aaagacattt acaacaactc ttccaaatat
     3481 tccagcagat gatgtccctc ttggtgctga cgaagatgaa aatgttgaaa tgcgccgctg
     3541 gggaaaacca cgtcaatttg attttgacat caaagcgcac tgggatcttg gcgaagatct
     3601 tgatattctt gattgggaac gcggttctaa agtaacaggt tcgcgtttcc tcttttacaa
     3661 aggtttggga gcccgcctag aacgtgctat ctataatttc atgctagatg aacacgctaa
     3721 agaaggctat acagaagtta ttccgcctta tatggtcaat catgattcta tgtttggcac
     3781 aggacagtat ccaaaattta aagaagatac ctttgaatta gctgacaatg attatgtctt
     3841 gattccaact gctgaagtgc ctttaaccaa ctactaccgc ggtgaaatca tcgatggtaa
     3901 agagcttcct atttacttta cagccatgag cccttctttt cgttcggagg ctggttctgc
     3961 tggtcgtgat acgcgtggac ttatccgcct ccatcaattt cataaagtag aaatggtcaa
     4021 atttgccaaa ccagaagatt cttataatga attggaaaaa atgacagcca atgctgaaaa
     4081 tatcctgcaa aaattagaat tgccatatcg ggttattacc ttgtgtactg gcgacatggg
     4141 cttttcggct gccaagacct atgacttaga agtctggatt cccgcacaaa atacttatcg
     4201 tgaaatttca tcttgttcca atacagaaga tttccaagca cgtcgtgcgc aaattcgtta
     4261 ccgtgatgaa gtcgatggca aggtgaaact tcttcacacc ctaaacggtt caggactggc
     4321 agttggacgt accgtcgcag ctatccttga aaactatcaa aatgcagatg gttccgtgac
     4381 gattcctgaa gtacttcgtc cttatatggg tggcactgag atgattgttc cttaactgat
     4441 tgcaacaatc ttattaagtt aatccttaat actatatata aaacatcatc tgaatgaaca
     4501 tcagcaacat tagttcattc agatgattta ttttttagcg tgctaaacaa taatcaaatt
     4561 ataggattgc tatctactta ttatgaggat tttgtggtat acatacatca ctcccatttg
     4621 tggctactta taggtaagta gaaattaaat ataagagatg aactctttac aaggggcata
     4681 aaaggcctca gtttttatct gataatgcct tttgacaaaa gcaacattag aaatagaaag
     4741 attggcgccc aataattctt tgaataaaga aatctcttct atgagtaata ataacctgaa
     4801 tgctatgtga gagacgttag gttattagat gtaatatacg gtcatctcct taaagataat
     4861 ttaacacaca aaaaaggaca tctaccattt agtgtaaata gtagatgtcc ttaccttaat
     4921 tgtacaagca acttcttctt gtattcaaaa ataaaggttt aacgagtact gcagttgaga
     4981 atcaaccaaa tctgccagtt ttattcacaa gcagttgcac cttgaaggat accaccaatt
     5041 gcaccatagg ttccaccaag taaagcccct gctgcaggac cgactccgcc accttctgca
     5101 gcaggagcag aaacagcagc acctatagct gctcctgctc ctgcccctgt aagagcgcca
     5161 tacaccatac cacccaaaac tcctgacgta cattgccaat cgccaccttg taccttagca
     5221 agcaaatctg catctaatac atcaaagtgt tctaatgttt gagttgtcat aagatacctc
     5281 ctcttttttt atagtgaata aattaattac aatattgtga cgcaccgtat aatccattgc
     5341 taataccacc taaaacagca ccaatacccg cacctgctgc aggaccgatt ccaccacctt
     5401 ctgcaacagg tgcagagaca gcagcagcta tagttgcacc tgctgcgcca cctgcgaggg
     5461 ctccttctat aaccttacca gttgttcctg caaagcattg attaacacca cctactactg
     5521 tagcaagcaa atctgcatct aatacatcaa agtgttctaa tgtttgagtt gtcataagat
     5581 aaaccccatt tctttttatt gccagctttc tcatctgaca agcacattat agaaactttt
     5641 taatagcttg taaaccccaa tagtctaaag aaagttagaa ttaatgttta tgttaaagag
     5701 aagaaaaatt atagattgtt tattaaactt tcaaataaat tagttaaaaa taaatagaat
     5761 ctattagttt actaagaaag aaacaatact tattcaccga aattattatt ccctttatga
     5821 agatttccag aaataattga cagtttcgat aaaagctatt ctaacttcag acttaaataa
     5881 ctaaatattt ataaaacacc aagcgtgact ttttgagcct taaaaaaaca gatacttcga
     5941 aaccaaaaga ctcctcgctt tgaacataca aatagagaga accaacttga tcctctctag
     6001 atgttagatt agccatctgc tacaattgaa aatgtgtcaa atgttttctg tagactttat
     6061 cttcagtttg aaacttattt ggaacagtct taactgttat taagcccaaa acaacaataa
     6121 ttactgtgaa gttcaccata gtaggtaagg tgtcaatcta ttgattaaac gcatggcaga
     6181 aaggacagcg agaagaagta gcgcagaaga ttcaatgcgg ataagtgaaa tcatctcatt
     6241 atcaattgcc cacaaaaagc ctggaaagca aactaatgca atcgctatta caaatagatt
     6301 tgataatttc tcctcaccat tgttaataac tgtcatcata agaatgtttg atatgatgat
     6361 aattgctata caaatgataa aagaactttt tcttctcacg ataaccacct caaaacgtag
     6421 actaatttaa ccaatgccta agttaggttg ccagaccata atgtatgcac ctgaagctgc
     6481 acaagtagta aggtatgcag ctccaactcc ccaaccaatt ggaccggtag ccatacaaac
     6541 agccatagtt gcatcaccat aaaccgtagc accagcaaaa acacgctccc aattgactcc
     6601 gccttctact tctataccgg caagcatatc atctaaattt ttatttatag ttactataat
     6661 taagtaattt taagaaaaaa tcaagaaaat ttaagattca gcataaatgt ttaatatatt
     6721 tgaaatatct agagcatttt tctttaaatt aaagtaaaat agaagtctaa taagtttaca
     6781 attaaaattt aagacagatc aacttccttt tctttcttac gactctaaaa ctaacagaga
     6841 aagaacattc tcttgtttcc cacaaattta acgagacttc atgattaatc acaaagaatc
     6901 aaaatagagc ttactatgaa aaataaggtg cagatgaatg cagacttttt ataaattaaa
     6961 taaagtaaag taatgatatc agtaaacgac gactacagga ttaaagtatt ttaatacttg
     7021 acaaatagca tatgtcaaat caataaaaag atagagtaaa ttagacatct taatcactac
     7081 cataaaatga tattgtatgc acctaatctg agatcttcat gaacaagttc cagaaatatc
     7141 actcaattta tcactaaagc cagattcgtc tgcactttgc caatcacagc ttccaccttc
     7201 aacaccagaa aatagttccc tattctaaaa cccttttcat tttttagttt cttgcctaat
     7261 tgcacaatcg atatctttaa taacaatata acaatttatt tttgaagtgg agtaaaatat
     7321 cctatgtttt aggcataggc agtataaaca gtcctagctg cagataccaa catgacaagt
     7381 accgtgcaat aagtcacgtc tatctaacct tttaaatgtt taactttaat aaggcatcgc
     7441 gaataagcga taatatttgt gtgataatct tattgagtgt gagtgacttt ttacttgttt
     7501 tatcagctat cgtttgagaa aaatctgatt ttttcgctat tggatcaggt gtttcccctc
     7561 ttttttggtt aggtgcaggt tcaccgcttc ctggaacagc tgtaaccttc tcgtcagtaa
     7621 ctttggtatt ctctttatct gtatttggtg cttctgcagg agcgatccca ttattttcag
     7681 attcatattc ttttttctgg attgtatgac tatataactt gttatacagg ttttgtgctg
     7741 taataccgct acctacccaa ccagatatta actgaccttt atcaatatat aaagtagttg
     7801 gagtagcaaa catacctact tttttagtga gaaattcctt ggctgcaacc gtaaaatcgt
     7861 ccctatctgt attataataa taaagttgag aacctgttaa accattaaat tcttttaaaa
     7921 ccggagaaaa atcccgacag taatgacagg tgggacgacc gatatacaaa atgtaatcgt
     7981 tctctgaatc atcaaacatg tgataaacat ctgccatact gacagctttg aaattagcaa
     8041 catttgcttc gtattcttca acggaaactc cttctgatac tgtattcttg ctatctgata
     8101 ttttttcagt tgatgagctg gtatccacct cttgttgagg cggctgagaa ttttctataa
     8161 cttggtcaga tgtctccaaa gaagtttcgc gaacactatt ttcatcactg cgtttgctct
     8221 tattctcaga agaagtaact gtcgaagcag tcgttgctgc tggtgctact gtttcctgaa
     8281 caacagtaac atcagcactt tgagtttctg ttgtgactgc aggtgcagac acttccgttt
     8341 tttctattcc ctgaggagtt tcctcctctg cataagcaac accagctgct agtaataata
     8401 gcgaggccga acataataat agtgttttat aatatttcat tgtttcccat tctcctttta
     8461 taatagaatt tagccttact ctttaaatat tagaaactag ctcaatctgt tatttcctag
     8521 aatcaaaaaa gttcaattaa ttatcatatt cccaaacaat agaataatac tattccaaag
     8581 aattatttta taggcctttt atttttcgtt tctgtcttaa tatttctaaa acaattacta
     8641 ctaatcatat gtaatttttc ctaatgatag ctgctgaatt aatgatgtat caatataaaa
     8701 aataaaatgt cgtaaaggta ataagaaatc aagtatattt ttttaatttt aaaatagata
     8761 ttatcgctat ttggaagaat cccgaaaaaa taaatacaga agatagaact ctacgcatat
     8821 caaggttaaa cttacaaaaa tatcagtact gcgaaaaatt ccaactatcc ctaatatcat
     8881 aaaaatagct aaacctactt tagttctcat tactttaact tttatcaaca aaaacttccc
     8941 gctgcaattg taccggctgt catggcaact ccaacaggac ctccaactac tgctaagcca
     9001 tcataaatac ttgctcccac aagggcagca cacctaggat ctcgaccacc accttgaata
     9061 ttttccaatg catcagtatt taatatttta aaattattat attgtttttc catagtaagc
     9121 gctccttaat tatttacata aagcataagc tctataatat cgaaagtggg ttgacctact
     9181 atagatatta tagagccgtt ttttcatttt ttcttccaaa gactataagc taaaccaata
     9241 gctaggccaa tcaaaaggca taatacttta gacatattaa ttacctccaa caagttcacc
     9301 gtatgcatct aagccaccag ctattccaag gactccacca acggggttac cacctgcacc
     9361 aatgagacca ccaacgccac ctgaaaaacc agctttatcg gctcctttcc aactacatcc
     9421 cccaccttca atagctgaag gtacttgact atccatgacg tcaaattgtt ccaatacgtg
     9481 tgtatccata tgataaacac ccctttttca ttttaaatat tgtctagttg tgcaaccaac
     9541 atctttagta taacaattta ttttcaaaat ggagcaaaat atcctaaacg gtagctattt
     9601 tgtcctaaac ggtaaaaatg ccaaatttct attagaaatt gacaaattga cccttcctga
     9661 caaattagca actttgcctg taccgcatca agttagataa ctatgaaaaa cgaaagcttt
     9721 ttagttctca tctactttaa ttagcttctt tcaaaattaa aataataaac atgaaaagaa
     9781 agactaaaat gaatcttaga caaaaaatag ttttagaaga tagcaaagct tttatcccaa
     9841 ataaaagtaa gattagcaga atctttagta ttatcaacaa aatgtactta tccttatttt
     9901 atttttatct tgctgtattc tctaaaaacg ccaaataaaa acaatagcat accgatagat
     9961 gcaaacatca tctgccaaat gttatttgaa gtcaaaagaa ccttaactcc taaaaatatg
    10021 attatcaagg caaaaggtac tactaaatac tttttcatgg cttacctcca aacatatttt
    10081 ctataatttt tcaattaaat ttactaaaag cagaaagctg ctgctccgat catcgcctca
    10141 ttaattattc ttcatggacc acctacaaga ggtatattct aatgctatag cggtaacaac
    10201 gaccgcagga gaactactct attagtaata atatcaaatt taaaaataat aatattgact
    10261 taaaaatttc attgttctcc ttttattata gagcgtagat ttacttttta ataagtaatt
    10321 ctgttactta aactttagaa gttagattaa tcagttattt ctaaaatcga gaataaaacc
    10381 aatcaatcat catattccaa acaatagaat aatgctattc caaagaatta tcttacagat
    10441 cttctgacct gcacccaaaa agttggacag aaaatctaac gattggggtg ttttttgatg
    10501 aaattaacgt acgaaaataa actcaaaata tatgagctga gaaagaatgg gatgtcgtgg
    10561 tcccaactta atcaaaagtg tggtgtgagt ctgtctaatc tcaaatatat ggtaaaactc
    10621 atggatccat atgatcttga aagagttaga aaaggaaata acatttactt atccccagaa
    10681 ttaaagcagg aaatgattga tacactcctg aaagtccaat taattaaagt aaactctaat
    10741 cagtggatac ttcaagaaga ttactttaca ttaataataa tttttaacaa ttgttcctat
    10801 tcagcattat attgcctgaa agtaaaaact gtttagcgtc tcttatgcag tttaatgagt
    10861 tcaattagat tccagatgat aacaataact aagagtatat ttacaataat taaagcagtg
    10921 cgctgagtcg tatcattagt tgtaattgct cggtaagagc acactaatag aactaaaaac
    10981 gaaaagatag tcacggcggt ttgagtttga tactgagtaa attgctgttc tgctataggg
    11041 cgttggttta gttctttata ggcaagataa gctactagga aaaccaataa agacagtatt
    11101 ccaagcggaa gccagagcca aatagaactt ttactatcta tcatatggaa acaaagatca
    11161 agagccaaaa aaccacttag aacagcacct aacctaagaa aacgtaatac tctagaactg
    11221 cattttgata atctcattaa cttacctttc tatctgtaac atatataaaa agatgatatc
    11281 ttcagtaacc taaccatatt aaatcattca actcttgaat aattgataat ctgacatgta
    11341 atcattagaa aaataatgcg ataagctaag tgaatagaaa tacctacttt ttaatttttt
    11401 caataaccca atctattaac gaaccaagga ctattaaaaa catcaaaata agattaatat
    11461 ccataaaatg agcttgtttt gtaatacttg cataaacatt cagaataacc ataaccatta
    11521 atccaaatgt ataaatgatt accgtcttcc ttttttcaca gatgcgagcc gctttaaccg
    11581 actggtcctc ttttttcatt ttcctagaaa tccattcggc cagtagacag aaaaataaga
    11641 taaacacaaa agtaagatta gaagcaacaa attgaattcc tcttttgata cttatataac
    11701 ccttcataat aataagacca ataaaaatac atgttacagc aaccgctact tttcttttct
    11761 cacgagaata agtaattttt gctttttgtt tacttttttt catcatacct tctttattct
    11821 atttcttctt gtacaggata tacttgtagg ggtgttagat tgtagttaac aaaaagtcca
    11881 cttggataca tactgtaagt gaccaaacaa acgaagatcg tccaagcaaa tcgtaattag
    11941 cctttgttat caaaatacca tcggtgagag gtttaaaaag gtatgaattt tggttagatc
    12001 aaaccatctt ttataactta ggatttttta actagcacca cagatttatt taatgaatta
    12061 taaataaagg ttctaattaa ttcattaaaa ataaatcaat tccataaact tttgatgaat
    12121 atttttcatt gttgaagtcc ctctacttat gttttaaagt ttttaagcta acattattgg
    12181 agcaagtaac atagccaatg tataaattgt tataaaaaca tgtatgatgg aagaaaaagc
    12241 agatcttaga cttacttttt aataatggac ttattactta aactttagaa attcgtttaa
    12301 ccagttattt ctaaaaccaa tcaaccatca tattctcaaa caaatataat aatactattc
    12361 caaagaatta tcttatagct cttcttgttt attttccttt ttttgtttta atatctctaa
    12421 aataatcact acgtccaata gtataataca attattaatc aattttgctc tgatcattca
    12481 caagttctcc cataggtcac catatgatta gatccttctt tcctctagtt atgcctctac
    12541 actatcacta atacctaaac gcatttgtag caatattatc tttctagacc aaatgactgg
    12601 tataaaacag aaaatcttca cctacctttt tcaatcttct gcattttaaa agttactgtt
    12661 ctaaatataa aagtgatttc atgcttttct atgcggtcta ttgacctcct ctgaaaaata
    12721 aaagataaag gatgaagttt tctttgtcca acttctttag acaatttctt catagatcag
    12781 ataaattaac tttcataaaa ggaaaagact cttctggttc agataaatat gaacgcattt
    12841 ttaaaagttg cttaattctg ttacaatgat attagttctt atccccttct agtttacttt
    12901 tactattttc tagaatatag aactcttttt gttttagaaa cttctgctaa gaattgtttt
    12961 atactaatcc aacttgatca ttttattttt taggacctag atttatctgt taatagtact
    13021 gaaatatggg taaagttaaa ttaataaatt actgttttgg tttttgcaga gttttaattt
    13081 gactgactaa ctatcagaag taccaagagt ataaaaagcc taccatgtat ataatggaaa
    13141 gacttaatga tgtttttgat tagttatcag atttttttga acgctactgt gtctttttta
    13201 catattttat tccccataat aaaagaagag agataataaa actgattaca gcggcaatta
    13261 agaaaatgat tctgctggca aattcgctta cttgaattgt tttataactg cttaaaaccg
    13321 tcaaaaggaa aaaaacggca gtaaggacaa cttgactagt aattgtagca gccgaacttt
    13381 cttgtgaatt aacctctctg atttccttaa taaaataata atttagacca gcagtacaaa
    13441 atgttataat tacaaagcaa atctgaacaa gcaggggaga tttaaaaata gcttgtgtca
    13501 aaaccaaaat taacagacaa acagctatca gctgcgctgt taaaagtctt aataacctaa
    13561 gtttctgact ttccttttta aacatttctt ttctccttta ttctaaatat aacttatcag
    13621 atgagtttgt ccatcaatgt aaaataaaca aagggaggag aaaaatcaaa atttccgtat
    13681 ttgtatcttt ttctgcctcc ttaaaaatta aattactaac cacaggaatt aagagctcct
    13741 ccgattcctc cagcaatagc cccaaaggca ccagtgccaa tagcatatgg accaagaaat
    13801 gctgtaccgc ctgcagtagc catataacct tgcccagcac ctagagcaat acctgctgca
    13861 caattccatc cgcggccccc accttcaaca gctgaaagtg cttcattatc cattacgtta
    13921 aattgttcaa atgcttgtgt attcatatga taaatacccc ttttccattt ttagtttttt
    13981 gtctggctgc gcaaccgaca tctttagtat aacaatttat tttcaaaatg gagcaaaata
    14041 tcctaaatgg tagctatttt gtcctaaacg gtcatttttg atgttctgaa actatcatta
    14101 ccagctaatt ttacattatg tgtcctaagg aaaagatgac tttttcaaga aaatccatga
    14161 ttttttcata aaaaatagta tactaattat agtcaaaaaa aggagatata aaatgaaaaa
    14221 aacaccatca ttaaaaaatg actttaaaga aattaagact gatgaattag agattatcat
    14281 tggcggaagc ggaagcctat caacattttt ccggctgttt aacagaagtt ttacacaagc
    14341 tttgggaaaa taagataggc taacattaga ataaaacaag gctggatttg ttattccaac
    14401 ctttttaaat gtaaaataag aatacagggt taaataatca agtgtgctgt cgtggatgag
    14461 aagataaaac tatctcttag agaataggcc tcctctattt cattattagg agttgcttga
    14521 ataaatgatg atgactgctt gtttgtaaac tggttttggg ataatgttca agaatatgat
    14581 tcacctttgc taaaccaata ccgcgattgg agcctttagt ggaatagttt tctttaaaaa
    14641 ttttactcac atctatttgt ttttctttgg aggaattctg gatgataaag actatgctgc
    14701 catttttctt aaaaaaggct aactgaattt caggttttag tgattcgaga gcggcctcaa
    14761 tagcattatc gcacaagata gaaagtatag taatgaaatc aagcaactcc atatcaggca
    14821 gctgtatttt acctgagacc tctacattga cagcaatttt tttattttga gcttctaaga
    14881 tttttgctga taagataccc ttgacagcat cgttttgaat attagctaga tggccgatat
    14941 tataacgggt atcctgcaat tgatgtcctg ttttttctaa gatttgatgg taaatctttt
    15001 caatactagc taaatcttta ttttcaatgc ctaatctgag gctagttaaa atattcagat
    15061 aatcatggcg gaaacttcga atatccttgt aaagagattc tatttgctga ctatactggg
    15121 tgatatttcg aatctgagct tccttttgtg ccattatctc attttgaacc ttttgtttgg
    15181 tatattggct taaaaatgag atcagaatca aaaataaaat aagatagaca ataacgacaa
    15241 atttacgaaa ttttaaagtc ggtatcacat tataactctc tataatatac aatgcctgta
    15301 ttaaaaggta gtatagaagc atagtaatat tcattgggat caagcgtttt ttgaccttca
    15361 tcttggtcaa actatcttta agtcgaccaa tatcaacatt gaacacactt agaaagaggt
    15421 aacttagcgc tattcctgca aactcgatca tataggtggt tataatgcta ctgtccatta
    15481 caattccttg atttccatcc aagataaaga atatgattgc ccgcctaaac aagtcagaac
    15541 tggcaacagg cagcagacca taaaatatat ttagagaaag actattctgt ctattaagat
    15601 aaattgataa aactataaaa taaagaggct ctgcaggata aaacaggttt acatttacca
    15661 tcgtaacagc aatcattatc agaaaattgc ttatcgaaaa aagagttaat tcctttttcg
    15721 ataaagtgac attacttacc ttagaaaata gaaacaagag aaatagaacg gttagataag
    15781 ttaataaacc atttgaaagt atcattaagg cttcattcat tttgctctcc tttgatcagc
    15841 aatcacagct ctcagttttg ttaacttagt tcgtgaaata agacaagact tattatttcg
    15901 aaaataggcc aagcgttttt tccgatcaat acgggtaata ttggcaggat tgacaataaa
    15961 agagcgatgg cactgaaaaa gtctcttatc cattttaaca atgttagtca tactgccgta
    16021 gaattcaatc cgttcatcat aagtataaag gcagagctta tgggctgttg aagatgtttc
    16081 aaaatacaga atctcagcaa aagggacctg aaactgaatt tcagatgaat ggaaaataaa
    16141 aagttcctct gattgaccat tcttctggct gttttccata gcataataca gcgctgattc
    16201 aatgcggtgg gagaactcct caggattcaa agatttatca ataaaatcca aagcagatac
    16261 ctgatactga aaagtgaggg gcataaactc agaatgtgtc gtgacaaaga caataaccgc
    16321 actaggatta tgctgtctaa tctgattggc tacttccaat cctttctttt cctctttttt
    16381 gatttcaata tccaaaaaga aaatctggtg actgcccttt tcagggatag tatcaataag
    16441 ttgttgtggt ttcccaaaaa tagtcaattc tttataagac cagttctttt ctttcatgat
    16501 agctgcaatg gtggtttcaa gacgtccttg ttgtaaaaaa tcatcttcca atacaaaaat
    16561 agaaatcatt atttctcctt taatcttctg tttaggttag ctgattaaca ctatacacag
    16621 aaaaggtata aaactatatt actcaataaa atttactgac ttaatagccc tacttatcta
    16681 ttcgcaatat aatcagatga ttaagcattt tttgttcatt ctagtgataa taaacatttt
    16741 gctaaccgca aaaaaagaaa agtttcttct ataagtatga accgctgtaa attatgttcg
    16801 attatatcac agttctctaa aactgttaac cactttgact cacctatgct attttcaaaa
    16861 aagtgataag caatagatat agccttaatc ccttgaagat aacaaatcaa tcttaaagaa
    16921 gatttctttg atcatgttca actcttctac atattctata cggcaaaaaa cgactgatta
    16981 acagcattag cattactgct ttttttctgt taatcagccg ttgtcaattg attatataat
    17041 tattttttct ttttgctggt tttgacgaca gtaatagcac ttggtagtaa agtcacaaaa
    17101 acaatagcca agataatagc agaaaaatgt gttttaacaa aaggaatgtt accaaaaaga
    17161 tagccagctc ctgtagcaat cactgtccaa gataaagcag ctataaaact gcgtttaata
    17221 aaagaagaca cagggaattg actaaggcca gctacaaagg gaacaaaagt tctgataatt
    17281 gggatataac gtcctaaaat gatagaagtt gaaccgtatt tttcaaaata aagctcagca
    17341 tctttgatat tatcttcttt aataaattga ctgaaaaatt tgtgatgcac caaacgataa
    17401 ccagccgtac gaccgataaa gaaattacag gtatctccaa caaaagcagc tatgaaaaat
    17461 aaaataccaa aaactaaaac actaaagtgc atcttaggat tggctgctaa ggcacctgct
    17521 gcaaataaga ggctgtctcc cggcagaaaa ggaagaatga cgacacccgt ttccacaaag
    17581 attactaaaa atagaattag gtaagtccac aagccaacgg tattggcaat actataaata
    17641 tagttatcaa tatgtaaaat aaaatcaata aaaaacataa tttttttcta ataatcctaa
    17701 atccctttag actgctgttt gatacctata atttagttgc ttgataatat ggcatcaatt
    17761 tatcaaagcc ttgagccaat tgatcagtta gtataactag atctgatccc tctgatatag
    17821 gtatgtcata cttgaccaaa acttttcgaa cttgaccgtc agcaactttt tgccgtaaca
    17881 tctgacgata agcttctgtt cctgaaaccc gatgactttc acttttctct tgagcaaaat
    17941 aataaagcgg ttcagcaatc ggtatgtcta aaactttatg ctgtttagct agagtcgcct
    18001 ttgatttttt gcgttcaata aaactgacct ctactgaaat accaaaatta gctgaattcc
    18061 cataaagcct gatagcaagt ccaacatcgt cctggttatc ttcaggttgt ttataatagc
    18121 accaaaaatg cggtctggca acttgtgcct gattagccca attactgaca cgcatcatct
    18181 caaaaggaga aactttaaga gcaagcacct tagctatctc tgtaaattca gcacgcgcag
    18241 attgtcctaa ggttttcaaa gctatcattt cttcagccaa ggaaccagcc ttttctggtt
    18301 taatatactt aaaaccttgc tgtgtcaaat aagcttttag attttcaaac attttttcct
    18361 ttccatacaa cctatctatg cttgctttat tgttaaaagc ctaaaagtaa gaaagcaaag
    18421 actaccttat ttccgtttcc ttgcaatcaa gcggataggg gttccttcaa atacaaaagc
    18481 cttacgaatt tgattttcta aaaagcgcag gtaggaaaag tgcatcagct cttcttcatt
    18541 gacaaaaata acaaaggttg gcggcttgac tgatacttga gtggcataaa aaatcttcag
    18601 ccgtttcccc ttatctgtcg gtgttgggtt aactgcaaca gcatccataa tcacttcgtt
    18661 taaaacagcc gaaggaatgc gggtgttttg actttgactg atttgcttaa tcatatccgg
    18721 cagcttatga agacgctgtt tcgtaagagc tgatacaaaa acaatcggtg catagggaat
    18781 atattgaaac tgctcacgaa tatcggtctc ccactgagcc attgtatgat tgtctttttt
    18841 aatagtatcc cacttattca caacgacaac aatcccttta ccagcctcat gagcaaaacc
    18901 agcaatgcgc ttgtcgtatt cacgaatacc ttcctcagca ttcaac
//
