LOCUS       NZ_JAQCYD010000001     27148 bp    DNA     linear   CON 23-FEB-2024
DEFINITION  Streptococcus mutans strain AF36-21BH AF36-21BH.Scaf1, whole genome
            shotgun sequence.
ACCESSION   NZ_JAQCYD010000001
VERSION     NZ_JAQCYD010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptococcus mutans
  ORGANISM  Streptococcus mutans
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 605237)
  AUTHORS   Lin,X., Hu,T., Chen,J., Liang,H., Zhou,J., Wu,Z., Ye,C., Jin,X.,
            Xu,X., Zhang,W., Jing,X., Yang,T., Wang,J., Yang,H., Kristiansen,K.,
            Xiao,L. and Zou,Y.
  TITLE     The genomic landscape of reference genomes of cultivated human gut
            bacteria
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 605237)
  AUTHORS   Zou,Y., Lin,X. and Hu,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-NOV-2022) BGI Reaserch, BGI-Shenzhen, Beishan
            Industrial Zone, Shenzhen 518083, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. v2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100x
            Sequencing Technology             :: MGI
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/23/2024 01:23:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,988
            CDSs (total)                      :: 1,943
            Genes (coding)                    :: 1,890
            CDSs (with protein)               :: 1,890
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 33 of 53
            Pseudo Genes (incomplete)         :: 28 of 53
            Pseudo Genes (internal stop)      :: 23 of 53
            Pseudo Genes (multiple problems)  :: 22 of 53
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:29:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 50051
            Orig. end                         :: 77199
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAQCYD010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..27148
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..27148
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..27148
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:22148]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..22148
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     misc_feature    439..454
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 23.25"
                     /tool="antismash"
     gene            888..1187
                     /locus_tag="PGX70_RS00225"
     CDS             888..1187
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002278146.1"
                     /locus_tag="PGX70_RS00225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_042669255.1"
                     /transl_table=11
                     /translation="MNTVTLDSMAFDHFETAGEDYLTGIEGEGILGAVAYGLCQGAVGG
                     ISGFGAGLGVSIALAQVSPPMAAEAAPWLIGVGTIAGAVGGLVQGSAEGWKNGW"
     misc_feature    1348..1361
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.27"
                     /tool="antismash"
     misc_feature    1349..1362
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.54"
                     /tool="antismash"
     gene            1468..1692
                     /locus_tag="PGX70_RS00230"
     CDS             1468..1692
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297299.1"
                     /locus_tag="PGX70_RS00230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_270513554.1"
                     /transl_table=11
                     /translation="MDTMAFENFDEIDMNHLASIEGEFDIKGVSAAASYLAVGTAALGG
                     LACTTPVGAALYLGAEVCASAASIYYGAN"
     gene            1711..2118
                     /locus_tag="PGX70_RS00235"
     CDS             1711..2118
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263726.1"
                     /locus_tag="PGX70_RS00235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_002270936.1"
                     /transl_table=11
                     /translation="MIIKDEKTRRIIFLLSWLLLATGLALVEWSHSKIIAILLFTIITV
                     MAVFSFFSMTKAQEKNNESDPKVNDSVDSNMMANRTRKIIYLLSWFLFAIVTAVITWRY
                     SKIIAALVFIAITAVSIFSFFSIIKVEGKKQ"
     gene            2385..2546
                     /locus_tag="PGX70_RS00240"
     CDS             2385..2546
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PGX70_RS00240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_162470319.1"
                     /transl_table=11
                     /translation="MSKTYATISIMVGIGASIALARVSPPMAAEAALWLIGVGTIAGAG
                     VNTWGPWI"
     gene            3018..3227
                     /locus_tag="PGX70_RS00245"
     CDS             3018..3227
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002280956.1"
                     /locus_tag="PGX70_RS00245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_002263944.1"
                     /transl_table=11
                     /translation="MFSKKSIIVSYTYMLAIPICLMLYAIFPSIRDFVSTIYLIGTMLV
                     IIFCWKDFFKLMQLLRDYWKNKKG"
     misc_feature    3299..3319
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 28.76"
                     /tool="antismash"
     misc_feature    complement(3341..3355)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.69"
                     /tool="antismash"
     gene            3465..3743
                     /locus_tag="PGX70_RS00250"
     CDS             3465..3743
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002279528.1"
                     /locus_tag="PGX70_RS00250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_002310898.1"
                     /transl_table=11
                     /translation="MNAVTLDSMAFDHFETAGEDYLVDIDGSGFVGSIAGGVLGAGTGF
                     TAGFKPAQFLWRVPVAGSYLALGTLGLTTVAGVYIGAREGWGDGGFW"
     misc_feature    complement(4966..4980)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.34"
                     /tool="antismash"
     gene            5001..7283
                     /locus_tag="PGX70_RS00255"
     CDS             5001..7283
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0043214 - ABC-type bacteriocin transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0043213 - bacteriocin transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="resistance (resist) ABC_efflux"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298141.1"
                     /locus_tag="PGX70_RS00255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="WP_002266017.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.1e-41, bitscore:
                     136.9, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 0.0, bitscore: 1096.6,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQVIYVVLIVIAVNILLEVIKRVTKRGGTVSSSNPLPDGQSKLF
                     WRRHYKLVPQIDTRDCGPAVLASVAKHYGSNYSIAYLRELSKTNKQGTTALGIVEAAKK
                     LGFETRSIKADMTLFDYNDLTYPFIVHVIKGKRLQHYYVVYGSQNNQLIIGDPDPSVKV
                     TRMSKERFQSEWTGLAIFLAPQPNYKPHKGEKNGLSNFFPLIFKQKALMTYIIIASLIV
                     TLIDIVGSYYLQGILDEYIPDQLISTLGMITIGLIITYIIQQVMAFAKEYLLAVLSLRL
                     VIDVILSYIKHIFTLPMSFFATRRTGEITSRFTDANQIIDAVASTIFSIFLDMTMVILV
                     GGVLLAQNNNLFFLTLLSIPIYAIIIFAFLKPFEKMNHEVMESNAVVSSSIIEDINGME
                     TIKSLTSESARYQNIDSEFVDYLEKNFKLHKYSAIQTALKSGAKLILNVVILWYGSRLV
                     MDNKISVGQLITFNALLSYFSNPIENIINLQSKLQSARVANTRLNEVYLVESEFEKDGD
                     LSENSFLDGDISFENLSYKYGFGRDTLSDINLSIKKGSKVSLVGASGSGKTTLAKLIVN
                     FYEPNKGIVRINGNDLKVIDKTALRRHISYLPQQAYVFSGSIMDNLVLGAKEGTSQEDI
                     IRACEIAEIRSDIEQMPQGYQTELSDGAGISGGQKQRIALARALLTQAPVLILDEATSS
                     LDILTEKKIISNLLQMTEKTIIFVAHRLSISQRTDEVIVMDQGKIVEQGTHKELLAKQG
                     FYYNLFN"
     gene            7297..8199
                     /locus_tag="PGX70_RS00260"
     CDS             7297..8199
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263524.1"
                     /locus_tag="PGX70_RS00260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="WP_002263524.1"
                     /transl_table=11
                     /translation="MDPKFLQSAEFYRRRYHNFATLLIVPLVCLIIFLVIFLCFAKKEI
                     TVISTGEVAPTKVVDVIQSYSDSSIIKNNLDNNAAVEKGDVLIEYSENASPNRQTEQKN
                     IIKERQKREEKEKKKHQKSKKKKKSKSKKASKDKKKKSKDKESSSDDENETKKVSIFAS
                     EDGIIHTNPKYDGANIIPKQTEIAQIYPDIQKTRKVLITYYASSDDVVSMKKGQTARLS
                     LEKKGNDKVVIEGKINNVASSATTTKKGNLFKVTAKVKVSKKNSKLIKYGMTGKTVTVI
                     DKKTYFDYFKDKLLHKMDN"
     gene            8549..10213
                     /locus_tag="PGX70_RS00265"
     CDS             8549..10213
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264777.1"
                     /locus_tag="PGX70_RS00265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transcription antiterminator"
                     /protein_id="WP_002302914.1"
                     /transl_table=11
                     /translation="MIILDRNSYDLLSYLIKLEEPETVMSISKVLNQSRRKVYYHLDKI
                     NEALPSEIPKIISYPRIGILLSSQQKAACRTLLADLDDYSYVMSIQERMLLSITYIAIA
                     KDRVTIEKLMQINAVSRNTILNDLNELRQRLSFEPYSIKLQATKSKGYYLDCHPLSKIQ
                     YLNKLLHTIYTDSNPNFIAMMRDKLRDFADLSSYFSDDISSFIRGELQVSQALLGKKIN
                     SQDIRFMVATLPYQLLSYQNLGLSEREQRDLLSEFSPIKERKEYEIARHLNENLKREFH
                     LELDEIETSLIAVLLLSYRKDRDMHLESHDYDDMRRVLSYFIDAFELDYHVCFKHKQLL
                     LNQLLTHCKALLFRKAYGIVSNNPLTDQIKDKYADLFAMTKVCLSILENAWSIKMNDDD
                     IAYITIHIGGELVHSETKPTPPAVLTLVCDEGIGVQKLFMQQCKQYLPHSKIEAVLTSE
                     QFYSVADIMAVDLVISTNDSLDTQLPTLFVHSILRDDDAIKLIRFAKQRGQTGQDDFDK
                     KLETYIRHYVKNDSDCYVLKTKIEGLINEELLYDNKR"
     gene            10795..11886
                     /gene="ulaG"
                     /locus_tag="PGX70_RS00270"
     CDS             10795..11886
                     /EC_number="3.1.1.-"
                     /GO_function="GO:0030145 - manganese ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA]"
                     /GO_process="GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ulaG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /locus_tag="PGX70_RS00270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="WP_002263526.1"
                     /transl_table=11
                     /translation="MTNVKDITRESWILSTFPEWGTWLNEEIEEEVVPANNFAMWWLGN
                     CGVWIKTPGGANVVMDLWSNRGKSTKKVKDMVWGHQMANMAGVRKLQPNLRVQPMVIDP
                     FAINELDYYLVSHFHSDHIDINTAAAIVNNPKLDHVKFVGPYECGEIWKKWGVPEDRII
                     VIKPGDSFEFKDIKVTAVESFDRTCLVTLPVEGAKENNDDLKGLAVTDEEMARKAVNYI
                     FETPGGTIYHGADSHFSNYFAKHGKDFDIDVAINNYGDNPVGIQDKMTSIDLLRMAENL
                     RAKVIIPVHYDIWSNFMASTDEILVLWKMRKERLQYQFHPFIWEVGGKYTYPQDKDRIE
                     YHHPRGFDDCFEHDSNIQFKALL"
     misc_feature    12015..12033
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.99"
                     /tool="antismash"
     gene            12260..14236
                     /gene="tkt"
                     /locus_tag="PGX70_RS00275"
     CDS             12260..14236
                     /EC_number="2.2.1.1"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="tkt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1204: transketolase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289129.1"
                     /locus_tag="PGX70_RS00275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transketolase"
                     /protein_id="WP_002280276.1"
                     /transl_table=11
                     /translation="MSDLSVNAIRFLGVDAIEKSKSGHPGVVMGAAPMAYSLYTKHLRV
                     NPSQPNWINRDRFVLSAGHGSMLLYALLHLSGFEDISIDEIKNFRQWGSKTPGHPEYGH
                     TVGVDVTTGPLGQGISMAVGLAQAERFLAAKYNREGYPIFDHYTYVIAGDGDFMEGVSG
                     EASSYAAKQNLDKLIVLYDSNDICLDGETNDAFTESVRARYDAYGWHTILVEDGNNIEA
                     IGLAIEEAKAAGKPSLIEIKTVIGYGAPTKGGTNAVHGAPLGAEEATATRKALNWGYAP
                     FEVPQEVYDDFKENVADRGEAAYDAWSNLVGEYRQAYPKEAREVDAIIDGKDPVEIKEA
                     DFPVYENGFSQATRNSSQDAINAAADVLPNFLGGSADLAHSNMTYIKADGLQDADHPLN
                     RNIQFGVREFAMAAVLNGMALHGGLRVYGGTFFVFSDYLKAAVRLSALQGVPVTYVFTH
                     DSIAVGEDGPTHEPIEHLAGLRATPNLVVFRPADARETQAAWHYALTSQNTPTALVLTR
                     QNLDVEAGSSFTSVAKGAYVTYETDSDFNTILLASGSEVNLAVKAAKELEAQGEKVRVV
                     SVPSTELFDEQSAAYKEAILPNSVRRRVAIEMAASQPWYKYVGLDGAVIGIDKFGASAP
                     AAQVIENYGFTVDNVVKVVKGLK"
     gene            14796..15764
                     /locus_tag="PGX70_RS00280"
     CDS             14796..15764
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002279439.1"
                     /locus_tag="PGX70_RS00280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_270513555.1"
                     /transl_table=11
                     /translation="MKLMITKQFQSFLQELGIDIRLVLQKAQLPNKLWQEELTYNAQEY
                     YCFIATLDKLITDEALLALSRIENIKKFVPAFFAALASPDGLTALQRFLKYKSLIGPVK
                     VQLEDSGDEISASYAYCSSQLPLPRMLLLQEQLLLLSLLRTGTGTCILPYEISSPYDYG
                     RLLEKEAGILPKKTDYNRLVLSKADLEKPFITENNVMWYHLKLSLNQQLSQLHSDDNFT
                     QAVQTELLSAIPSGQFSLAMIANRLGLSARTLQRKLAAEDTTFNEEVLHIQKLMTFSYL
                     DLSMSVDEIAYLVGYSEKSSFLRAFKKWTGKTLKQYKETAL"
     gene            16007..16519
                     /locus_tag="PGX70_RS00285"
     CDS             16007..16519
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019805026.1"
                     /locus_tag="PGX70_RS00285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HXXEE domain-containing protein"
                     /protein_id="WP_002278379.1"
                     /transl_table=11
                     /translation="MTAALFAFIAITLFMIHEFEEIILVCPWIAKNKSDPKFANEIFIS
                     GRKHYPSAENIAVAVLEEFVLASLILLAGILFRVPELVLAITLGHTFHLFSHISQAITY
                     RTWVPGSITAALTLPLLVMAIMGFCFAQTLSWMLLLMLTVLIFPLQLVNLRFLHQQTDK
                     VEKFLHS"
     gene            16594..17046
                     /locus_tag="PGX70_RS00290"
     CDS             16594..17046
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002281093.1"
                     /locus_tag="PGX70_RS00290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="WP_002266702.1"
                     /transl_table=11
                     /translation="MGTMKLRIEQDDQYKELEIHITYGQKDKLIERILGFLETVDRQLS
                     CYQEGRKYLVNFSDIYYIESVDKKTFVYLADEVYQTDLKLYQLLHDLQHDGFVQISKSC
                     LLNINVLENIRPLFNSRMEATLLNGEKVIVNRRYLPDVKEALKGIR"
     gene            17046..17429
                     /locus_tag="PGX70_RS00295"
     CDS             17046..17429
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019321898.1"
                     /locus_tag="PGX70_RS00295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_002263531.1"
                     /transl_table=11
                     /translation="MRKAVTNFFATTGISLILLSLFALYFQAHWLLLVTIFQVFLVNIL
                     IHLALLTRQKWEFQQELVGSLLDLVIIEGIIYSLSFPFHWNASLWVLLSIGLIIYLISR
                     LLDLFYLGQEAQEINSLIKKRRQ"
     gene            17447..18421
                     /locus_tag="PGX70_RS00300"
     CDS             17447..18421
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019805027.1"
                     /locus_tag="PGX70_RS00300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="2-dehydropantoate 2-reductase N-terminal
                     domain-containing protein"
                     /protein_id="WP_002282704.1"
                     /transl_table=11
                     /translation="MKILVIGLGTIGSIYGYVFQKAGHEVEHYLRKDSPKVAVKQLQVD
                     LLDGRADKDGIQSCDVYQVKHCSSKTYDFIFVSVPSGGLTSVIDSLAADGISGTLILAC
                     GIWEDRAYVDKLVKGYSYILGYPVAGGNIRDNRLTCCLFDHFMLERKEKAAISNYEKLA
                     KLFADCQIQLEQPYDMLEWIWLHMGINAGVISVMGKSGDVKDTAAAAEQLMDSIQYLKE
                     AVKTIRETSQIVASRGVNLKHYKNELLAYKLPTVISAPLMKRMFAKKVLTRKIMTLHGN
                     TQDLMFVCKCLYDSGKKNQIAAPNFYANCEETMGKITSLMEKK"
     gene            18580..21216
                     /gene="polA"
                     /locus_tag="PGX70_RS00305"
     CDS             18580..21216
                     /EC_number="2.7.7.7"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /gene="polA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019314525.1"
                     /locus_tag="PGX70_RS00305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DNA polymerase I"
                     /protein_id="WP_270513556.1"
                     /transl_table=11
                     /translation="MTNKKKLLLIDGSSVAYRAFFALYNQIDRFKNPAGLHTNAIYGFH
                     LMLDHMMKRVEPTHVLVAFDAGKTTFRTEMFADYKAGRAKTPEEFREQLPYIREMLTAL
                     GVSYYDLENYEADDIIGTLDKLAENEDEYDVTIVSGDKDLIQLTDSNTTVEISKKGVAE
                     FEEFTPDYLMEKMGLTPKQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEHGSLEAIY
                     EHIDSFKTTKMKENLINDKEKAFLSKTLATIDTQAPITITLDDIDYSGPQLDALAKFYD
                     EMDFRQFRSQLDSSPKAGNFEVNYTEVTELKPDMFAPDQFFYFEILNDNYHTQEMIGLA
                     WGDDQAIYATTDTSLLTHDLFKEALSKPIKTYDFKRGKVLLSHLGIDLPTASFDSRLAK
                     YLLSTVENNNISTIARLYTDLPLETDDDVYGKGAKRAIPEKNVLLSHLAKKISVLLASE
                     EPMRQKLSANDQLDLLFEMELPLANVLAKMEIAGISVRKETLQDMERANEIELQALTQE
                     IYDLAGEAFNINSPKQLGVILFEKLGLPLSATKKTKTGYSTAVDVLERLAHRSPIVAKI
                     LEYRQIAKLQSTYIIGLQDSISFDGKIHTRYLQDLTQTGRLSSVDPNLQNIPVRLEQGR
                     LIRKAFVPEWKESVLLSSDYSQIELRVLAHISGDEHLIAAFKEGADIHTSTAMRVFGIE
                     RPEDVTPNDRRNAKAVNFGVVYGISDFGLANNLGISRKAAKNYIETYFERYPGIKNYMD
                     RVVREARDKGYVETLFHRRRELPDINSRNFNIRSFAERTAINSPIQGSAADILKVAMIH
                     LDQALKKGDYQSRMLLQVHDEIVLEVPNAELEAIQKLVKETMESAIELSVPLVADENAG
                     QTWYEAK"
     gene            21309..21737
                     /locus_tag="PGX70_RS00310"
     CDS             21309..21737
                     /GO_function="GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002266707.1"
                     /locus_tag="PGX70_RS00310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CoA-binding protein"
                     /protein_id="WP_002263534.1"
                     /transl_table=11
                     /translation="MAYQFQNPSQHVIFDYVKRAKTIAIVGLSARKETAAYDVAQVLQS
                     AGYKIIPVNPRAVGDEILGETVYARLQDIPEHIDIVDVFRRSDFLADVARDFIETDADV
                     FWAQLGLQSQEAEKILRFAGCDQIVMNKCLKIEYLKLN"
     misc_feature    21314..21328
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: medium, score: 23.46"
                     /tool="antismash"
     gene            complement(21930..22148)
                     /locus_tag="PGX70_RS00315"
     CDS             complement(21930..22148)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002270875.1"
                     /locus_tag="PGX70_RS00315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="garvicin Q family class II bacteriocin"
                     /protein_id="WP_002267385.1"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 8.7e-08,
                     bitscore: 27.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTRMMEQFETMDAETLSHVTGGGLYDGANGYAYRDSQGHWAYKV
                     TKTPAQALTDVVVNSWASGAASFAAYA"
     misc_feature    complement(22288..22303)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 24.32"
                     /tool="antismash"
     misc_feature    complement(22496..22509)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.88"
                     /tool="antismash"
     gene            22559..23701
                     /gene="tgt"
                     /locus_tag="PGX70_RS00320"
     CDS             22559..23701
                     /EC_number="2.4.2.29"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="tgt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) bTGT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002266496.1"
                     /locus_tag="PGX70_RS00320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="WP_002266496.1"
                     /sec_met_domain="bTGT (E-value: 4.8e-189, bitscore: 623.0,
                     seeds: 1816, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHSPIQYRLIKKEKHTGARLGEIITPHGVFPTPMFMPVGTQATV
                     KTQSPEELKEMKAGIILANTYHLWLRPGDDLVARAGGLHKFMNWDQPILTDSGGFQVYS
                     LAEKRNITEEGVTFKNHLNGARMFLTPEKAISIQNNLGSDIMMSFDECPQFYQPYDYVK
                     ASIERTSRWAERGLKAHRRPQDQGLFGIVQGAGFEDLRRQSTADLVSMDFPGYSIGGLA
                     VGESHEEMNAVLDFTTPLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTRIARNG
                     TCMTSRGRLVVKNAQYAEDFTPLDHDCDCYTCQNYTRAYIRHLIKADETFGLRLTSYHN
                     LYFLLNLMEKIRQAIMDDNILEFREDFIEKYGYGRSERNF"
     gene            23701..24264
                     /locus_tag="PGX70_RS00325"
     CDS             23701..24264
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285338.1"
                     /locus_tag="PGX70_RS00325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_002262916.1"
                     /transl_table=11
                     /translation="MDEEQLKTLLLANEPISRILTIIRDLKLSDAWLCAGTLRNFIWNY
                     LSGKPAFDKETDIDVVFFDQTISYEKTLRIEKELQAAYPAYQWELKNQIYMHVHSPNTE
                     PYHNSCDAIAKYPEKCTALAARINDKGKLELFLPYGLEDIVQFKVAPTPHFLADEERMR
                     VYQQRLLKKHWQNKWPQLQFLKGD"
     gene            24691..25704
                     /locus_tag="PGX70_RS00330"
     CDS             24691..25704
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002268229.1"
                     /locus_tag="PGX70_RS00330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YdcF family protein"
                     /protein_id="WP_002262915.1"
                     /transl_table=11
                     /translation="MLGLLAVVLFILLVVSIYHEARSLLNPILLIVFLMVSYLAIIEFL
                     YSHGYYTAYGVFLLLLISTPLIIFLGGLFLVYNGIILLHKEGFSKINLLSLCLGLMITS
                     FFLFMVIRIHHSTHLLFNRFIASLYALLSASFLIFSVAFIAFMLYSILYLIIPKNKHYD
                     YIIIHGAGLLHGNQVTPLLKRRIDKALEAFRQSKNSQVKLIASGGLGSGETISEAAAIA
                     NYIRKQASDIPNDRLLLEEQSHSTYENLLFSKQLAEKEMKKPRFLFVTNAYHVFRTSVY
                     ARRLHMAGDGLGCSTAAYYIPSAFIREFIAIVVYLKWLFIIVYAWFIIALIYSFFR"
     gene            25781..26557
                     /locus_tag="PGX70_RS00335"
     CDS             25781..26557
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264123.1"
                     /locus_tag="PGX70_RS00335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_002266499.1"
                     /transl_table=11
                     /translation="MKLTTLGCWGAYPYKDEGTTSYLLTGEDGFQLLIDCGSRALNELE
                     KEISPLDLDAVIISHYHPDHVADLGVLRHYFQLYPKHLWTPKVLPIYGHDQDTYEFSKL
                     TLDGVSEGRAYNVNGLEQIGSFDITFIKTVHPVVCYAIRIVERTTGQIFVFTGDTGYFE
                     DLDKFAAGADLFLADVYLYEGNENHIAHLTTKEAGQIASAAKVKRLVLTHMPPVPPAGI
                     DPDNHLEILRSQTEAYSNGIPVELATPHKSWQIGNC"
     gene            26557..27027
                     /gene="tadA"
                     /locus_tag="PGX70_RS00340"
     CDS             26557..27027
                     /EC_number="3.5.4.33"
                     /GO_function="GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /gene="tadA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1240: riboflavin biosynthesis protein RibD"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304824.1"
                     /locus_tag="PGX70_RS00340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="WP_002276391.1"
                     /transl_table=11
                     /translation="MAGLTQAEKEFFMGEALKEAQLSLQKEEIPIGCVIVKDGQIIGCG
                     HNAREEENLAIMHAEIMAINQANRTQESWRLLDCTLFVTIEPCIMCSGAIGLARIPQVI
                     YGAKNAKFGGAGSLYDILTDERLNHRVEVERGILEKECAQMMQSFFRYRRTK"
ORIGIN
        1 ggagacttga atccttcgtc agatttgcca acgcatgtcg agttgtacaa agctttcccg
       61 gaagttggtg gtattgtcca tacacactca actgaaggcg tatcttgggc acaggccggc
      121 cgtgatattc cttgttacgg aacaacacat gcagatacct tctacggggc aattccatgt
      181 gcgcgtgctt tgactccgga agaaatcaat ggtgaatatg aaaaagaaac cggaaaagtt
      241 atcattgaag aatttaaaaa acgcggtctt gaccctttag ctgtttctgg tgtcactgtc
      301 cgcaatcacg gaccatttgc ttggggaaaa gacgaaaaat cagctgtata caatgcagtt
      361 gtcttggaag aagcagctcg catggcgaga tacacagaaa gtatcaatcc agaagtgaaa
      421 gaggtaccgc aagcactcaa agataaacat tatctccgta agcatggtaa gaatgcttac
      481 tatggacaaa aaggcgatag tcattaaaaa aaggagtgat tgtttcagat tgaagacaaa
      541 cttttcgagg tttgtctttt ttactttcag agagctcaat gaacaaaaca cccttttcct
      601 tttttgtgaa taaatctgtg tcagattaat ggagtgaaaa gaattttaga aagcatagaa
      661 aaacacaata taaaagataa ggcttcattt atataaaaaa gcccctcttg tcaatgttag
      721 tcaagatttt acaaaaacaa cggtcactat taagcaattc taatttaaca gaaaaatttc
      781 ctatactttt caaccagatg ttacagatat taaaattttg aaatattatt gcacctgtca
      841 ttttaacgtg ttaaaatgac agcaatatta agaagaggag aagttttata aacacagtaa
      901 ctttagattc aatggcattt gatcattttg aaacagcagg agaagattac cttactggaa
      961 tcgaaggaga aggaattctt ggcgccgttg cctatggact ttgtcaagga gctgtgggtg
     1021 gcatttctgg ctttggagct ggcctcggag taagtattgc attggcgcaa gtttctcctc
     1081 ctatggcagc agaagcagcc ccttggctaa ttggagttgg gactattgca ggtgccgtag
     1141 gtggcttggt acagggatca gctgaaggtt ggaaaaatgg atggtagtaa taaaatgtgg
     1201 aatatcttaa gtcgtctttt tatgattagc tgcataatat gtccgttaat tgctgcttgc
     1261 agtaaaggca ccatcattag gttgatttct tttggagcct ttgtattaga gtgtattgcc
     1321 ataacatttt atggtttata tttgttattt ttttaataaa aactgattgt aaattaggtg
     1381 acactctagt ataactgatt aactgtttac gaaattctgg atgactctca tgattgacaa
     1441 gttgatgtcc gatgggagcg ataggtgatg gacacaatgg cattcgagaa ttttgatgaa
     1501 atagatatga atcatcttgc tagtattgag ggagaattcg atataaaagg ggtttctgct
     1561 gctgcttctt atcttgctgt gggaactgca gcccttgggg gattagcgtg cactactcct
     1621 gtcggtgctg ccttatattt aggtgccgaa gtttgtgcaa gtgctgcatc tatttactat
     1681 ggtgctaatt aataattggg atatattaac atgataataa aagatgaaaa aacacgaagg
     1741 ataatttttt tactgtcttg gcttttgtta gccacgggcc ttgctttggt tgagtggtcg
     1801 cattcaaaaa tcatagcaat attactattt actataatca cagttatggc tgttttcagt
     1861 ttttttagta tgacaaaagc tcaagagaag aataatgaaa gcgaccccaa agtaaatgat
     1921 tcagttgaca gcaatatgat ggcgaatcga acacgaaaga taatttattt gctgtcttgg
     1981 tttctatttg cgatagtcac tgctgtcatt acatggcgtt attcaaaaat tatagcagca
     2041 ttggtattta ttgctatcac agctgtgagc atcttcagct tttttagcat aataaaagtt
     2101 gaagggaaaa aacaataaaa attttaaatt atctcctcac tgaaactata ggagctggtt
     2161 atagtctatg attaaacgca tatttcagaa tagtttgctt ccagtttttg taataatggg
     2221 attactggct gtatacacac cgataagacc ccttaagtac attcttgttg gtttaatggc
     2281 cttagaagga ctttctttca ttatgattga tggcgcaaaa ctattaaaaa gggttaaaca
     2341 ttaaaaatgt ttgaaggtgt gtaagcaaat ctaagccttt acgagtgagt aaaacatacg
     2401 caactatatc tattatggtc ggcataggag caagcattgc attggcgcga gtttctcctc
     2461 ctatggcagc agaagcagcc ctttggctaa ttggagttgg gactattgcg ggtgctggtg
     2521 ttaatacttg gggaccttgg atttaagctt tatcaggagg actaccatat gttgtcaccg
     2581 aaattaggaa gagctgttct ctttagttat cctatcttat tgctcatttc cttattatta
     2641 ccaattaaaa atattaaact gattgtattc atgatattta tgatagagaa tattttagta
     2701 ttaatatttt attggaaaag taaacatctc tcataagtaa tatgagagag actattaaaa
     2761 tgaattaata gcctaattct tacaagaatt aggctatttg agtaaagata ggtttaatat
     2821 gaatagaaat cgaaaataaa ttgttggttc cttagcaggt ccgaaggcag ttcctgttgc
     2881 ttctttagct ataggtgtaa cctttggtgg ggtatgtgga gccgttggtg gaggattcac
     2941 cggtgctgtt actgattatg agaaacttcc attttagtta cagtcatttt atttctcata
     3001 attgaaagga aaattttatg ttttcaaaga aatctatcat tgttagttat acttatatgt
     3061 tggctatacc tatttgtctt atgctgtatg ccatctttcc aagtataaga gattttgttt
     3121 ccactatata tctaatagga acgatgttag ttatcatttt ttgctggaaa gattttttca
     3181 aactgatgca actgctaaga gattattgga aaaataaaaa aggatgattt catgttctta
     3241 catgaatctt ttagatagtg taccttttat attaatgatt tcaatcatat ttctctttaa
     3301 atataggata gacaatattt tgaaatacta ataaaataat aattatcaga aaatctatac
     3361 taatttttcg ttttgtttcc atcaaagtta aaaactagaa acattattga acctgttatt
     3421 taaaaatgct aaatgacagc aatatttagc aaaagagaag ttttatgaat gcagtaactt
     3481 tggattcaat ggcatttgat cattttgaaa cagcaggaga agattacctt gtagatattg
     3541 atggctcagg ttttgttgga tcaattgctg gtggagtttt aggagctgga acagggttca
     3601 cagccggttt caagccagct caatttttgt ggagagttcc agttgcagga tcgtatctag
     3661 ctcttgggac tctcggcttg actacagtag caggtgttta tattggtgct agagaaggat
     3721 ggggagatgg aggcttctgg taattaacag cttctagtta tctattgaat catttctata
     3781 tattggaaat cagttgtatg acttcaattg gtactatact tattaaagta ggtgtagagt
     3841 taactttaat aatttcaata atattttctt ttggaatacg aatgttagtc tattctaggt
     3901 ataaggtatg ttattgaatt cattaaaata tcagcacaaa tttagaaaag gtaatattag
     3961 tttatgcaca taattcagtc aattttagtg ttacttgctc tttgtgtatt agcacttatt
     4021 tcttaccgta gtaaaaacat tattatttca tttatatgtg tcatcatttt gcttgcttta
     4081 tttgcttatt atcttttgca ttagtgaaag caaaagtatt ttcaaattta aatttagtca
     4141 agttaataac ttgtggtgct agtttagtag cctagttcta aaagatgaaa ctattataca
     4201 atttattaat tttattctta atcaataaaa gttcaaatta ttggttatat gatggtttta
     4261 tgatactgcc gcttatatta cactatagta aaagttcatt tgataagctc gcttgtttta
     4321 ttatttttct gtttgaatgt atttggctcc ttgtcaactg tagtgggtgg catttctggc
     4381 tttgcagctg gttatagcct atgattaaac gcatatttca gaatagttcc agtttttgta
     4441 ataatgggat tactggctgt agacacaccg ataaggcccc ttaagtacat tcttgttggt
     4501 ttaatggcat tagaaggact ttctctcatt gtgattgatg gcgcaaaact attaaaaagg
     4561 attaaacatt aaaaatgtta aaatctctta aagagttgag atgatcgact cactttattt
     4621 aagtactcaa atctagcttg ggtcagatca ttttggaatg ctaacaaata atagctatca
     4681 gaaaagttgt aagattcttt ctttttatta tcatctgtat taaagttctg gaatattatt
     4741 gtatatgctg ttttaaaatg ttaaaatgat gatgtttaga gaattagaga aggagaagtt
     4801 tatgaatatg ttaattttgg attcaatgac attagaagga ttctctcatt atgattgatg
     4861 gcgcaaaact gttaaaaaag gttaaacatt aaaaatgtta aaatctctta aagagttgag
     4921 atgatcaact cactctattt aaaataactc aacctagttt gagttatttt tctgaatata
     4981 aactaagaaa gattattttt atgaaacaag ttatttatgt tgttttaatc gtcatagccg
     5041 ttaacattct cttagaggtt atcaaaagag taacaaaaag gggagggaca gtttcgtcat
     5101 ctaatccttt accagatggg cagtctaagt tgttttggcg cagacattat aagctagtac
     5161 ctcagattga taccagagac tgtgggccgg cagtgctggc atctgttgca aagcattacg
     5221 gatctaacta ctctatcgct tatctgcggg aactctcaaa gactaacaag cagggaacaa
     5281 cagctcttgg cattgttgaa gctgctaaaa agttaggctt tgaaacacgc tctatcaagg
     5341 cggatatgac gctttttgat tataatgatt tgacctatcc ttttatcgtc catgtgatta
     5401 aaggaaaacg tctgcagcat tattatgtcg tctatggcag ccagaataat cagctgatta
     5461 ttggagatcc tgatccttca gttaaggtga ctaggatgag taaggaacgc tttcaatcag
     5521 agtggacagg ccttgcaatt ttcctagctc ctcagcctaa ctataagcct cataaaggtg
     5581 aaaaaaatgg tttgtctaat ttcttcccgt tgatctttaa gcagaaagct ttgatgactt
     5641 atattatcat agctagcttg attgtgacgc tcattgatat tgtcggatca tactatctcc
     5701 aaggaatatt ggacgagtac attcctgatc agctgatttc aactttagga atgattacga
     5761 ttggtctgat aataacctat attatccagc aggtcatggc ttttgcaaaa gaatacctct
     5821 tggccgtact cagtttgcgt ttagtcattg atgttatcct gtcttatatc aaacatattt
     5881 ttacgcttcc tatgtctttc tttgcgacaa ggcgaacagg agaaatcacg tctcgtttta
     5941 cagatgccaa tcagattatt gatgctgtag cgtcaaccat cttttcaatc tttttagata
     6001 tgactatggt aattttggtt ggcggggttt tgttggcgca aaacaataac cttttctttc
     6061 taaccttgct ctccattccg atttatgcca tcattatttt tgctttcttg aaaccctttg
     6121 agaaaatgaa tcacgaagtg atggaaagca atgctgtggt aagttcttct atcattgaag
     6181 atatcaatgg gatggaaacc attaaatcac tcacaagtga gtccgctcgt tatcaaaaca
     6241 ttgatagtga atttgttgat tatttggaga aaaactttaa gctacacaag tatagtgcca
     6301 ttcaaaccgc attaaaaagc ggtgctaagc ttatcctcaa tgttgtcatt ctctggtatg
     6361 gctctcgtct agttatggat aataaaatct cagttggtca gcttatcacc tttaatgctt
     6421 tgctgtctta tttctcaaat ccaattgaaa atattatcaa tctgcaatcc aaactgcagt
     6481 cagctcgcgt tgccaataca cgtcttaatg aggtctatct tgtcgaatct gaatttgaaa
     6541 aagacggcga tttatcagaa aatagctttt tagatggtga tatttcgttt gaaaatcttt
     6601 cttataaata tggatttggg cgagatacct tatcagatat taatttatca atcaaaaaag
     6661 gctccaaggt cagtctagtt ggagccagtg gttctggtaa gacaactttg gctaaactga
     6721 ttgtcaattt ctacgagcct aacaagggga ttgttcgaat caatggcaat gatttaaaag
     6781 ttattgataa gacagctttg cggcggcata ttagctattt gccgcaacag gcctatgttt
     6841 ttagtggctc tattatggat aatctcgttt taggagctaa agaaggaacg agtcaggaag
     6901 acattattcg tgcttgtgaa attgctgaaa tccgctcgga cattgaacaa atgcctcagg
     6961 gctaccagac agagttatca gatggtgccg gtatttctgg cggtcaaaaa cagcggattg
     7021 ctttagctag ggccttatta acacaggcac cggttttgat tctggatgaa gccaccagca
     7081 gtcttgatat tttgacagaa aagaaaatta tcagcaatct cttacagatg acggagaaaa
     7141 caataatttt tgttgcccac cgcttaagca tttcacagcg tactgacgaa gtcattgtca
     7201 tggatcaagg aaaaattgtt gaacaaggca ctcataagga acttttagct aagcaaggtt
     7261 tctattataa cctgtttaat tgagaaaggg gataacatgg atcctaaatt tttacaaagt
     7321 gcagaatttt ataggagacg ctatcataat tttgcgacac tattaattgt tcctttggtc
     7381 tgcttgatta tcttcttggt catattcctt tgttttgcta aaaaagaaat tacagtgatt
     7441 tctactggtg aagttgcacc aacaaaggtt gtagatgtta tccaatctta cagtgacagt
     7501 tcaatcatta aaaataattt agataataat gcagctgttg agaagggaga cgttttaatt
     7561 gaatattcag aaaatgccag tccaaaccgt cagactgaac aaaagaatat tataaaagaa
     7621 agacaaaaac gagaagagaa ggaaaagaaa aaacaccaaa agagcaagaa aaagaagaag
     7681 tctaagagca agaaagcttc caaagataag aaaaagaaat cgaaagacaa ggaaagcagc
     7741 tctgacgatg aaaatgagac aaaaaaggtt tcgatttttg cttcagaaga tggtattatt
     7801 cataccaatc ccaaatatga tggtgccaat attattccga agcaaaccga gattgctcaa
     7861 atctatcctg atattcaaaa aacaagaaaa gtgttaatca cctattatgc ttcttctgat
     7921 gatgttgttt ctatgaaaaa ggggcaaacc gctcgtcttt ccttggaaaa aaagggaaat
     7981 gacaaggttg ttattgaagg aaaaattaac aatgtcgctt catcagcaac taccactaaa
     8041 aaaggaaatc tctttaaggt tactgccaaa gtaaaggttt ctaagaaaaa tagcaaactc
     8101 atcaagtatg gtatgacagg caagacagtc actgtcattg ataaaaagac ttattttgat
     8161 tatttcaaag ataaattact gcataaaatg gataattaga tattctatat atcagcagca
     8221 atctttgcta gaatagtttg aaatcagcta taacgctaaa gacttttgaa cttttaagtt
     8281 tttgttagcc ctaaaaggtg atgaatagct aatgtctgag aagaccaaac tggtcttctt
     8341 ttttgctagc tacagttgtt aaaagttccg taacataaag cagctcatag attgctctcg
     8401 aatgcaagtt tcttatggta aaaaatcgct gttcctatta aaagaaatcg tataagaggc
     8461 cgatttttta tctggatgat aaagtaagtc tcgctttaaa agtgtgctat aatgaaaata
     8521 atgaaatcga taacaaggga ggcaaaaaat gattatcttg gatagaaata gttatgacct
     8581 tctttcttat ttgataaagt tagaagagcc tgaaacagtg atgagcattt ctaaggtttt
     8641 gaatcagtcc agacgtaaag tttattacca tcttgataaa ataaatgaag cgctgccatc
     8701 tgagattccg aaaatcatta gctatcctcg cataggtatt ttgctttcat cacaacaaaa
     8761 agcagcctgc cgcactttgc tagcagattt agatgattat tcttatgtaa tgagtataca
     8821 agaacgtatg ctgcttagca taacttatat tgcaattgct aaagatcgtg ttacgattga
     8881 aaagttgatg caaatcaatg cagtttcccg taataccatt ctcaatgacc tcaatgaact
     8941 gcgtcaacgt ctttcttttg aaccatatag tattaagctt caggcaacca aatcaaaagg
     9001 ctattatttg gactgccatc ctctgtctaa aattcaatat ttaaataagc tgcttcatac
     9061 tatttataca gatagtaacc ctaattttat agctatgatg cgtgataagc tgagagattt
     9121 tgctgatttg tctagttatt tttctgatga tatttcaagt tttataagag gagaattgca
     9181 ggtttcccaa gcattactcg gtaaaaaaat caacagtcaa gatatccgtt ttatggttgc
     9241 tactttacct tatcagctgt taagttatca gaacctaggt ttatcagaac gtgaacaaag
     9301 agatttatta agtgaatttt ctcctatcaa agagcgcaaa gaatatgaaa ttgcgaggca
     9361 tttaaatgag aatctaaaaa gagaatttca tcttgaatta gatgagatcg aaacctcttt
     9421 aattgctgtt ttgcttttgt cgtatcgaaa agatcgcgat atgcatcttg aaagtcatga
     9481 ttatgatgat atgcggcgtg ttttaagcta ttttatagat gcttttgagc ttgattacca
     9541 tgtttgtttt aaacataaac aactcttact taatcagtta ttaacgcatt gtaaagccct
     9601 tctttttagg aaggcttatg gcatcgtttc aaataatccg ctaacagacc aaattaaaga
     9661 taaatatgca gacttatttg ctatgaccaa ggtttgtctt tctattttgg aaaatgcttg
     9721 gtctattaaa atgaatgacg atgatattgc ttatatcacc atccacattg gcggtgagtt
     9781 ggtacattct gagacgaaac cgacaccgcc tgcagtcttg accctagttt gtgatgaagg
     9841 cattggagtg caaaaactct ttatgcagca gtgcaagcaa tatttacctc atagcaagat
     9901 cgaagctgtc ttaacatctg aacaatttta tagtgttgct gatattatgg ctgttgattt
     9961 ggttatttca actaatgaca gtctcgatac gcagttgcca actctttttg tccattctat
    10021 tttaagagat gatgatgcca ttaaattaat tcgttttgct aagcagcgtg gacaaacagg
    10081 tcaggatgat tttgataaaa agttagaaac ttatattcgt cattatgtta agaatgatag
    10141 tgattgttat gtcctcaaaa caaaaattga aggcttaatc aatgaggaat tgctttatga
    10201 taataaaaga tagaaatata gtatgatatc tggaacgaaa tgccctccca gacttatttt
    10261 ttgtgaattt taaaattgag ccgctatcgc tctttgttca caatgcaaat aaaaaggctt
    10321 agaacttgta ttgacagttt tcttgggtgg tagagacgtc aaaaagccaa cgctatggta
    10381 ttggttacgt tttatactag aggctggtac aaaaaaagtg tactgggagt ttttttccta
    10441 acttctatcc cttgctctgc aaacgatagc tccaacagtt tgaaaaacta ttggagctta
    10501 tcttatttcg tgaacggtca attcatgtta atacctgaac aactttttcc actctttttt
    10561 cctaagttag cacttatctt atcaataaaa taatttctgt gaatacagtt tttttaagtc
    10621 tgaaatgttt ggtaggcaat gttaatgttt tttttatgag gccacactgt taagatagga
    10681 acagtccaaa tgtgaacaca agcttgtgtt ttatttggtc ttttgtaaag gctctggtag
    10741 cagtattata aatatgtaga aaaaataact atccaatgta taggaggaaa caaaatgact
    10801 aatgttaaag atattacaag agaatcatgg attttaagta ctttcccaga atggggcact
    10861 tggctgaacg aagaaattga agaagaagta gtccctgcca ataattttgc tatgtggtgg
    10921 ctgggtaact gtggtgtctg gattaaaact cctggtggag ccaatgtggt tatggacttg
    10981 tggtcaaatc gcggtaaatc aactaagaaa gtaaaagaca tggtttgggg ccaccaaatg
    11041 gctaacatgg caggtgtgcg taaattacaa ccaaaccttc gtgtgcaacc gatggtcatt
    11101 gatccatttg ccatcaacga attagactac tatcttgttt cccacttcca cagtgatcat
    11161 attgatatta atacagctgc agctattgtt aataatccca aattagacca tgttaagttc
    11221 gtcggaccat atgaatgtgg cgaaatctgg aaaaaatggg gagtgccaga agaccgcatt
    11281 atcgtgatta aaccgggtga ttcttttgaa tttaaagata ttaaagtaac tgctgttgaa
    11341 tcctttgacc gtacttgtct ggtaacctta ccagttgaag gtgcaaaaga gaacaatgac
    11401 gaccttaaag gacttgctgt tacagatgag gaaatggctc gcaaggcagt taactatatc
    11461 tttgaaactc ctggtggaac catctatcat ggtgctgatt ctcacttctc aaattacttt
    11521 gctaaacatg gcaaagactt tgatattgat gttgctatca ataactatgg tgacaaccca
    11581 gttggtattc aagataaaat gacttcaatc gatctccttc gtatggctga gaatcttcgt
    11641 gccaaagtca ttattcctgt tcactacgat atttggtcta atttcatggc ttcaacagat
    11701 gaaattcttg tcctttggaa gatgcgtaaa gaacgtttgc aatatcaatt ccatcctttc
    11761 atttgggaag ttggtggtaa atacacttac ccacaagata aggatagaat tgaatatcat
    11821 cacccacgcg gttttgatga ctgctttgag catgattcta atatccagtt caaagccctc
    11881 ctataattgc tttttgcttt tcattcgttg tcaatttcac ctcgctgaac ttcagttcta
    11941 tctccggttc atttcttaaa ctgaaaggca aaatcaatca taggttatca ttcatctcat
    12001 ctgttccctc ttcgtcaact tcggcttgcc taactttaat tatgcctgcg tcttgtttcc
    12061 tcaattgaac agtgaatcaa ttattggttg atttatcgtt caatggtaca taaaataatg
    12121 ttaattatgt ctttaaactt tatatccgca tgtcgcacga tatgcgggta tttgaaagag
    12181 tttaaactta tttggatata tggaacaagt aagcgtttta tgttaaaata tctatgacta
    12241 cattaaaaag gagaatatta tgtcagattt atcggttaat gccattcgct ttttaggggt
    12301 agatgctatt gaaaagtcta agtcgggtca cccgggtgtt gtcatgggcg ctgccccaat
    12361 ggcttacagt ctatatacta agcatttacg tgttaaccca agtcagccaa attggattaa
    12421 ccgtgaccgt tttgttttgt cagctggtca tggctcaatg cttttatatg ctctcttgca
    12481 cttgtcggga tttgaagata tttctattga tgaaatcaaa aatttccgtc agtggggctc
    12541 taaaacaccg gggcaccctg agtatggcca taccgtaggt gttgatgtga caacaggccc
    12601 tcttggccaa gggatttcaa tggctgttgg tttggctcaa gctgaacgtt tcttagctgc
    12661 taaatacaat cgtgaaggct accctatttt tgatcactat acttatgtta ttgccggtga
    12721 tggtgatttt atggaaggtg tttctggcga agcgtcatcc tatgctgcca aacaaaattt
    12781 ggataaactg attgttcttt atgattctaa tgatatttgt ttggatggtg aaaccaatga
    12841 tgcgttcact gaaagtgttc gtgcacgata tgatgcttat ggatggcata caatcttagt
    12901 tgaagatggc aataatattg aagctattgg acttgctatt gaagaagcaa aggcagctgg
    12961 caaaccttct cttattgaaa ttaaaactgt gattggctac ggtgctccaa ctaaaggcgg
    13021 taccaatgct gttcatggtg caccacttgg agctgaagaa gcaactgcta ctcgtaaggc
    13081 tctcaattgg ggttatgctc cttttgaagt tcctcaagag gtttatgatg atttcaaaga
    13141 aaatgttgcg gatcgtggtg aagctgctta cgatgcttgg tcaaatcttg ttggagaata
    13201 tcgacaagct tatcctaaag aggcgcgtga agtggatgca attattgatg gaaaagatcc
    13261 tgtggaaatc aaagaagctg attttccagt ctacgaaaat ggtttctctc aagcaacgcg
    13321 taattctagt caagatgcca tcaatgctgc ggcagacgta ctacctaact ttcttggagg
    13381 atctgctgat cttgcgcatt ctaacatgac ttacattaaa gcagatgggc ttcaagatgc
    13441 tgatcatccg cttaaccgta acatccagtt tggtgttcgt gaatttgcta tggctgctgt
    13501 tttgaatggt atggctcttc atggcggact gcgtgtttat ggcggtacct tctttgtctt
    13561 ttcagactat ctcaaagcag ctgttcgttt gtcagctctt caaggagtac cagtaactta
    13621 tgtctttacc cacgattcga ttgccgttgg tgaagatggc cctactcatg aaccgattga
    13681 acacttggca ggtttacgtg ccactcctaa tttggttgtt tttcgcccag ctgatgcacg
    13741 cgaaacacag gcagcatggc attatgcttt gacaagccaa aacacaccaa cagctcttgt
    13801 tttgacacgt caaaatcttg atgttgaagc tggttcaagc tttacttcag ttgctaaggg
    13861 agcttatgtt acttatgaaa cagattctga ctttaatacc attcttttgg catcaggttc
    13921 tgaagttaac ttagcagtca aagcagctaa ggaattggaa gcacaaggcg aaaaagtacg
    13981 tgttgtttct gttccttcta cagagctctt tgatgagcaa tctgctgcct acaaagaagc
    14041 tattttgcca aattcagtac gccgtcgtgt agccattgaa atggcagcca gccaaccatg
    14101 gtataaatat gttggtcttg atggtgcggt tatcggtatt gataaatttg gagcatcagc
    14161 tcctgctgct caagtcattg aaaattatgg ctttacagta gataatgtgg ttaaagttgt
    14221 taagggactg aaatagtatt tttctaaatt catctgagta aggagtgaca ttcttctcaa
    14281 aattaaaaaa tgtaatgtta aaagctttta aaaacagctt cttagaaata ttgattttga
    14341 cctgcatctc aaaagttagc ctaaaatcta acttttgggg tgtttttcta tgaaattgag
    14401 ttgtgaagaa taacaggtaa gagactagat tagaatagtt agtttagcgt gaataacaga
    14461 tactgtgagt attttccatg gccttttgta agcagtaaaa aaatgaaaag gcttagtgag
    14521 aacctaaatt gtaagttgag tgttatatct tagctttcta atcctgcatc ttagttaatg
    14581 tgaggctttt ggcatcaatt gtcattgtag tgtcattgat tgtcctatgc aaaagccgct
    14641 tttttgcttt ataataatct gtgaaaaaaa ttgttgcaag ttagggatgt cacctaaatg
    14701 agctgactag aagttgaagc attttcaata aaagtcagaa agtaaacgga tgtattaatg
    14761 acttggctgt tcaagttgga cttggggtaa tgattatgaa actgatgatt acgaaacaat
    14821 ttcagtcttt cctacaagaa ttgggaatag atatcaggct ggttttacaa aaagcacagc
    14881 ttcctaataa gctgtggcaa gaagagctta cttataatgc tcaggagtac tattgtttta
    14941 tagcaacctt agataagctg attacagatg aagccttgtt agctttgagc aggattgaaa
    15001 acattaagaa gtttgtgcca gccttttttg ctgctttggc aagtcctgat ggtttgacgg
    15061 ctttacagcg ttttttgaaa tataaaagct tgattggtcc agtaaaagta cagcttgaag
    15121 acagcggaga tgaaatttct gcaagttatg cctactgttc atcacagctt ccgcttcctc
    15181 gcatgttatt gctgcaggaa cagttgcttc ttttaagtct cttacggacg ggaacaggga
    15241 cttgcattct tccttatgaa atcagttctc cttatgatta tggaagactt cttgagaagg
    15301 aagcaggaat cctgccgaaa aaaacagatt ataatcgttt agtattatct aaagcagatc
    15361 ttgaaaaacc ttttatcact gaaaataatg tcatgtggta tcatttgaag ttaagtctta
    15421 atcagcagtt gtcccagctt catagtgatg acaatttcac tcaggccgtt cagacagagt
    15481 tgctgtctgc catccctagt ggacaatttt cccttgcaat gatagctaac agactaggac
    15541 tcagtgcccg taccctgcaa cgtaaattgg ctgctgagga tacaactttt aatgaggaag
    15601 ttttacatat acaaaaattg atgacttttt cctatcttga cttatctatg tcagttgatg
    15661 agattgctta tttagtaggc tactcagaaa agtccagctt tctgcgggct tttaaaaaat
    15721 ggaccggcaa gacattaaag cagtataagg aaaccgctct ttaataattg atacggctac
    15781 gacactgtga aaaaagataa agacattcta atgctaaagc attttcgtca gctttcctat
    15841 tttgcggtat gtcgcttatg cctttgttat cttaagtaaa ttgaacacga gctaaaatcc
    15901 tagtaaaaaa gataaacttc cttgtgtctt ggcgacacgg cgtcagtttc ctatttttat
    15961 acggatttct aatgctcttt ggtatcttga ataaaggaga gaaataatga cagcagcact
    16021 attcgctttt atcgctataa cgctttttat gatacacgag tttgaagaaa taattttagt
    16081 ctgcccatgg attgctaaga acaagagtga tcccaagttt gccaatgaga tatttatctc
    16141 aggcagaaag cattaccctt cagcagaaaa tattgcagtg gctgtcttag aagagtttgt
    16201 tttagctagt ctgattctgc ttgcaggcat tctttttaga gtaccagagt tggtattagc
    16261 tatcacattg ggacatactt tccatctttt ttctcatatt tctcaagcca ttacctatcg
    16321 tacatgggta cccggaagta tcactgcagc attaactctt cctttactgg ttatggctat
    16381 catgggattt tgttttgctc agacacttag ctggatgctt ttattgatgc tgacagtcct
    16441 tatattccct cttcagttgg ttaatctgcg ctttcttcat cagcagactg acaaagtcga
    16501 aaaattcctg cattcgtaaa ttagattgta tttcagttat ctaatcctgc aacttggttg
    16561 atgcaggatt ttttgtggaa aagctgtgct ataatgggta ctatgaaatt acgaattgag
    16621 caagatgacc agtataagga attagaaatt catatcacat atggtcagaa agataagttg
    16681 attgagcgca ttctcggttt tctggagaca gtagacaggc agctcagctg ttatcaggag
    16741 ggcagaaagt atttggtcaa tttttcagat atttactata tcgaaagtgt ggacaaaaaa
    16801 acctttgtct acttggcaga tgaggtttat cagacggatt taaaacttta ccagttgctt
    16861 catgacctac aacatgatgg ctttgttcag attagcaagt cttgtttgct caatatcaat
    16921 gttctggaga atatacgccc gcttttcaac agccgtatgg aagccacttt attgaatggt
    16981 gaaaaggtca ttgtcaaccg ccgctatttg ccagatgtta aagaagcttt gaaaggaatt
    17041 cgataatgag aaaagcagtc acaaatttct ttgcaacgac gggaattagt ttaattttgt
    17101 tatctttgtt tgctctttat tttcaagcac actggctctt actggttacc atttttcaag
    17161 tgtttttggt taatatttta attcatttgg ccttgctgac gaggcaaaaa tgggaatttc
    17221 aacaagaact agtcggaagc cttcttgacc ttgtcattat tgagggaatt atctacagtc
    17281 ttagtttccc tttccattgg aatgccagtc tctgggtgct tttgtctatc ggtctgatta
    17341 tctacctgat atcccgtctc ttagatcttt tctatctagg acaagaagcg caggaaatca
    17401 actcacttat caaaaaacgc cgtcagtaaa gaagggaaat gttacaatga aaattttagt
    17461 aataggttta ggaacgattg gtagcatcta tggttatgtt tttcaaaagg cgggccatga
    17521 ggttgagcat tacctgagaa aagacagtcc taaagttgct gttaaacaac tccaagtaga
    17581 cttgctggat ggtcgagctg ataaagacgg catccagagc tgtgatgttt accaagtgaa
    17641 gcactgctcg agcaaaacct atgactttat ctttgtcagt gtcccatcag gcggccttac
    17701 ttctgtgatc gacagtctgg cagcagatgg tatttctgga acgttgattc tggcttgcgg
    17761 gatttgggaa gatcgtgcct atgttgacaa gttagtgaaa ggatattctt atattttagg
    17821 ttatcctgtg gctggcggta atatcaggga caataggctg acttgctgcc tttttgatca
    17881 ctttatgttg gaaagaaagg aaaaggcagc tatttctaac tatgagaagt tagcgaagct
    17941 ttttgctgac tgtcagattc aattggaaca gccctatgat atgctggagt ggatttggct
    18001 gcatatgggt atcaatgcag gtgttatttc agtcatggga aaatctggag atgttaagga
    18061 tacggctgca gcagcagaac agctcatgga ttctatacag tacttaaaag aagctgtcaa
    18121 aactattcgt gaaacttctc aaatcgtagc tagtcgagga gttaatttaa agcattataa
    18181 gaacgagctc ttagcctata aattaccaac tgttatttct gcacctctta tgaaacgcat
    18241 gtttgccaaa aaagtactga cccgtaaaat tatgaccttg catggcaata ctcaagattt
    18301 gatgtttgtc tgtaaatgtc tttacgatag tggtaagaaa aatcaaatag ctgctcctaa
    18361 cttttatgca aattgtgaag aaactatggg gaaaatcact tccttaatgg agaaaaagta
    18421 gaagattttg atgttggtga aggaaatcca acgattattt gataaaaatg aggcttgagg
    18481 caatagtgtc tcattttttt gtggcttatt tacttctttt taaccttatt gtcagtgttt
    18541 aaagagagta aagactagga tttatgttac aatagatcta tgacaaacaa gaaaaaatta
    18601 ttattgattg acggctcttc cgtcgcttat cgtgctttct ttgcacttta taatcaaatt
    18661 gaccgcttta aaaatcctgc tggtttacac accaatgcca tttatggctt tcatttaatg
    18721 ttggatcata tgatgaaaag ggtggaaccg acgcatgttt tagtggcttt tgatgctggg
    18781 aaaacaacct ttcgaacaga aatgtttgca gactataagg cgggccgtgc taaaacgccg
    18841 gaagaatttc gtgagcagtt accttatatt agagagatgc tgaccgcttt aggtgtttcc
    18901 tattatgatt tggaaaatta tgaagctgat gacattattg gaacccttga taaattagcc
    18961 gaaaatgagg atgaatatga tgttactatt gtcagcggtg ataaggacct cattcagctg
    19021 actgatagta atacgactgt tgagatttcc aaaaaaggtg ttgctgaatt tgaagaattt
    19081 acaccagact atctcatgga aaaaatggga ctgacgccta agcaatttat tgatctcaag
    19141 gctctcatgg gggacaagtc tgataatatt ccgggggtaa caaaaattgg tgagaagaca
    19201 ggtttgaaac tgttgcatga acatggcagt ctagaagcta tctatgaaca tattgatagc
    19261 tttaaaacga ctaagatgaa ggaaaatctc atcaacgata aagaaaaggc ttttctttct
    19321 aagacactgg caaccattga tacgcaagca ccgatcacca tcactttaga cgatattgat
    19381 tactctggtc ctcagcttga tgcactggct aagttttatg acgaaatgga cttcagacaa
    19441 tttcgatcac aacttgacag ttcacctaaa gccggaaatt ttgaagtgaa ttatacagaa
    19501 gtgactgaac tcaagcctga tatgtttgcg cctgatcaat tcttttattt tgaaattttg
    19561 aatgataatt atcataccca agagatgatc ggcctggctt ggggagatga ccaagcgatt
    19621 tatgcgacaa ctgataccag tttgctgacg catgatttgt ttaaagaagc cttgtcaaaa
    19681 cctattaaaa cttatgattt taagcgcggt aaggtcttgc tgagtcattt gggcattgat
    19741 ctgccgacag ctagtttcga tagtcgtttg gccaaatatt tgctgtcaac tgttgaaaat
    19801 aataacattt cgaccattgc aagactttac acagatttac ctttggaaac agacgatgat
    19861 gtgtatggta aaggagctaa acgtgctatc ccagaaaaaa atgttctgct cagccattta
    19921 gctaaaaaaa tcagtgtctt gcttgctagc gaagagccga tgcgtcagaa actgtctgcc
    19981 aatgaccaac tggacttgct ttttgagatg gaattaccgc tggcaaatgt gttggctaaa
    20041 atggaaattg caggtatttc ggttagaaaa gaaacgctgc aggacatgga acgggctaat
    20101 gagattgaat tgcaggctct gactcaggag atttatgatt tagctggtga ggcgttcaat
    20161 attaattctc caaaacaatt gggagttatc ctctttgaaa aattgggtct acccttgtca
    20221 gccactaaaa agacgaaaac aggttattca acagctgttg atgtcttgga acgtctggct
    20281 catcgttcac caatcgttgc taaaatttta gaatatcgtc aaattgcgaa attgcaatcc
    20341 acctatatca ttggcttgca agattcgatt tcctttgatg gcaagattca tacccgttat
    20401 ttgcaagatt taacgcaaac tggccgctta tccagcgttg atcctaattt acaaaatatt
    20461 cctgtgcgtt tggaacaggg acgtctcatt cgcaaggctt ttgttcctga atggaaagag
    20521 agtgttctgc tcagttcaga ttattcacaa attgaattgc gggtgctggc tcatatttca
    20581 ggcgatgaac atttaattgc tgcttttaag gaaggggcag acattcacac ctctacagcc
    20641 atgcgtgtct ttggtattga aagaccagaa gacgtcactc ctaatgaccg ccgcaatgct
    20701 aaggctgtta actttggtgt ggtttatggc atttctgatt ttggtctggc taataatttg
    20761 ggtattagcc gcaaagccgc taagaattac attgaaacct attttgaacg ttatccggga
    20821 attaaaaatt atatggatag agtggtgcga gaagcgcgtg ataagggtta tgttgaaacg
    20881 ctctttcatc gtcgccgtga attaccggat atcaattcac gcaatttcaa tattcggtct
    20941 tttgcggagc gaacagctat taactcgcct attcagggta gcgccgctga tattctcaaa
    21001 gtggccatga ttcatctcga tcaagccttg aaaaaaggag attatcaatc gcggatgctc
    21061 ctgcaggtgc atgatgaaat tgtccttgag gtaccaaatg ctgaacttga agcgatccaa
    21121 aagttggtca aggaaaccat ggaatctgct attgaacttt ctgtaccact tgtggcagat
    21181 gaaaatgcag ggcagacttg gtatgaggca aagtaaacag gtttatttat tactttaata
    21241 gcaattgtta gtttcactta ccgatttaaa agaggaaatt caagcgaaaa agttaaggag
    21301 gtcattttat ggcttatcaa tttcaaaatc ctagtcaaca tgtcatcttt gattatgtaa
    21361 aaagggccaa gacgattgca atagttggct tatctgcaag aaaagagaca gcagcttatg
    21421 atgttgctca ggtattgcaa agtgctggtt ataaaattat tcctgttaat cctagggctg
    21481 ttggtgatga gattttgggt gaaacggttt atgctcgcct gcaggatatt cccgaacata
    21541 ttgatattgt ggatgttttt cgccgcagtg actttttagc agatgttgct agggatttca
    21601 ttgaaacaga tgcagatgtt ttttgggcac aattgggact gcaaagccaa gaagcggaaa
    21661 aaatattacg gtttgccggt tgtgaccaga ttgtcatgaa taaatgtctt aaaattgaat
    21721 atctcaagtt aaactaagag ggcaatttat caaaaaacat ttagcgtttg tgctggtcat
    21781 ggtgttttag cacttaaaag gattgtcgtt tatttcaaac agattggcta gttcatactt
    21841 atgcgataat atcaaaaaaa cacctcatct attataatag atgaggtgtt tgccgtttat
    21901 ataacaatat gaacgattat cttaatgact taagcgtaag cggcaaaact tgctgcacct
    21961 gaagcccagc tatttactac aacgtctgtt aaagcttgtg ctggagtttt tgttacctta
    22021 taagcccagt gaccttggga atcgcggtaa gcatagccat tagctccatc gtaaagaccg
    22081 cccccagtta catgtgaaag tgtttcagca tccatagttt caaattgttc catcattctt
    22141 gtattcatgt gaatacctcc cttttttatt gttagtatat ctactaacat cgtcattata
    22201 actgttttta gtagagatgt gaacctgaaa ccgtttcaaa aatcggaact taactgttgt
    22261 gttaatcgag tgcaaaagac ttaattggat attaattttc aattgaaatt taaaatgaaa
    22321 aatcctgcag tacttagtat gaggaattga taatatgtct catattaaat tagtgtaaaa
    22381 gcagccaata gctatagtgt aggtgtttcg ttgtaccttt cttacactct caaaaaaaac
    22441 tgataaaagt tctgaatgca ggttctaaga agtacgctta atgacatctg ctagcttttt
    22501 tgataaaatt tataaggtta aactgtccaa aatacagtct tgaaagcaag gagtaaaaat
    22561 gacacattca ccgattcaat atcgtcttat taagaaagaa aaacacactg gagcacgttt
    22621 gggagagatt atcacaccgc atggagtttt tcccacccct atgtttatgc cagttggaac
    22681 acaggctact gtcaaaacac aatccccaga agaattaaaa gaaatgaaag caggaatcat
    22741 tttggctaat acctatcatc tttggttacg gccgggagat gacttggttg caagagcggg
    22801 aggtctacac aaattcatga attgggatca gccgatttta accgattctg gtggttttca
    22861 ggtttattca ttggctgaaa aacgcaatat tactgaagaa ggagtcactt ttaaaaatca
    22921 tctgaatgga gctagaatgt ttttgacccc agaaaaggcc atttctattc aaaataattt
    22981 aggttcagac atcatgatgt cctttgatga atgcccgcag ttttatcagc cttatgacta
    23041 tgtcaaagct tcaattgaac gaaccagtcg ttgggcagag cgaggcctca aagctcaccg
    23101 tcggcctcag gatcagggac tttttggcat tgttcagggg gcaggctttg aagatttgcg
    23161 gcgtcagtca acagctgatc tggtttcaat ggattttccg ggctattcca tcggcggtct
    23221 tgctgttggg gaatcgcatg aagaaatgaa tgccgttctt gactttacaa cacctttatt
    23281 accagaaaat aaacctcgct atctcatggg agttggtgca ccggacagtc taattgatgg
    23341 ggttattcgt ggcgttgata tgtttgattg tgtcttgccg actcggattg ctcgaaatgg
    23401 aacctgtatg acctcaaggg gacgcttggt tgtcaaaaat gctcagtatg cagaagactt
    23461 tacgccgctg gatcatgatt gtgattgtta cacttgtcaa aattatacac gcgcttatat
    23521 tcgccatctg attaaagcag atgagacctt tggacttcgc ttgaccagtt atcataacct
    23581 ttatttctta ctaaatctta tggagaaaat tcgtcaagcc attatggatg ataatatttt
    23641 agaatttcgt gaggacttta ttgaaaagta cggctatgga cgctcagaga ggaattttta
    23701 atggatgaag agcagttaaa gacattactg ctggcaaatg aaccgatttc tcgtatttta
    23761 accattattc gagatcttaa actttcggat gcttggttgt gtgcgggcac acttcgcaat
    23821 tttatttgga attatttaag tgggaaacca gcctttgata aggagacgga tatcgatgtt
    23881 gtcttttttg atcagacgat ttcttatgaa aagactttga ggattgagaa ggagttacag
    23941 gcagcttatc ctgcttatca atgggagctc aaaaatcaaa tttatatgca tgttcacagt
    24001 ccaaacacag agccttatca taattcttgc gatgctattg caaaatatcc agaaaagtgc
    24061 actgccctcg ctgctagaat aaatgacaaa gggaaattgg agctcttcct tccctatggt
    24121 ttagaggata ttgttcaatt taaagttgcc cccacaccac attttttagc agatgaggag
    24181 agaatgcggg tttaccagca acgtcttctg aaaaagcatt ggcaaaataa atggccacaa
    24241 ttacagtttt taaagggaga ttaaaatttt ttataagggt gaatgcctct gtttaccaga
    24301 gttattatca cttgaagata aacctacttt ttctatacat atatattttg aagttctgca
    24361 aatgccaatt taaatggtat tgatttgcga gcgaagtgag ccttaatcga gactttgtct
    24421 acactctgaa atcatctagc tctactagat gattttagat tatataatct aaaaaaatat
    24481 tttgaggact tacaaaggtg taaggttcta tcttgatttt tgagataaaa taaagatgga
    24541 agaattcctc agaagttaca aaagactaag attattagaa gagctttgct atttttgaat
    24601 tttttaagta ttttgttcaa aaaatgaaga gaatttcaaa tgtgacaatc aagattaaaa
    24661 atttaagtgt aataaaaata aggagatgtt atgttaggat tgcttgcagt tgtattgttt
    24721 attttgttag tggtttctat ttatcatgag gcacgaagtt tactcaatcc cattcttctt
    24781 atcgtcttct tgatggtaag ctatttggct atcattgaat ttctctatag tcatggttat
    24841 tatacggctt atggcgtttt cctgcttctt ttaatttcga ctcctcttat catatttttg
    24901 ggtggtctct ttttagtcta taacgggatt attctgttac ataaagaagg tttctcgaag
    24961 attaaccttt tatcgctttg tttagggcta atgattacta gcttcttttt attcatggta
    25021 atccgaattc accattcgac tcatttgtta ttcaatcgtt ttattgcttc tttgtatgcc
    25081 ttgttaagcg cttcttttct tattttcagt gttgccttta tagcttttat gctgtattcg
    25141 attctttatc tgattattcc taaaaacaag cattatgatt atattattat tcatggtgca
    25201 ggtcttttgc atggcaatca agtgactccc ttattaaagc gcaggattga taaggcttta
    25261 gaagccttta gacaatcgaa aaactcgcaa gtcaaattga ttgccagtgg cggtttaggt
    25321 tctggggaaa ccatttctga agcagcggca attgccaatt atattcgaaa acaggcaagt
    25381 gatattccaa atgataggct tctcttggaa gaacaatcgc attcgaccta tgaaaatctt
    25441 ctcttttcca agcagttagc agaaaaagaa atgaaaaaac cgcgttttct ttttgtaact
    25501 aatgcttatc atgtctttcg aaccagtgtt tatgcacgcc gattgcatat ggctggagat
    25561 ggcttgggtt gttcaacagc cgcctattat attcccagtg cttttattcg tgaatttatt
    25621 gctattgttg tttatttgaa gtggttattc attattgttt atgcctggtt cattatcgct
    25681 ttgatttatt ctttttttag ataacataag ctggttttta ttatccaaag agcagctcat
    25741 tttgttataa taaaaataac taaaaaaaga aggtgttttt atgaaactaa ccacacttgg
    25801 ttgctgggga gcctatccct ataaagatga aggaacaacc tcctatctct tgacaggaga
    25861 agacggtttt cagctcttaa ttgattgcgg tagccgtgca ctcaatgaac tcgaaaaaga
    25921 aattagcccg ctagatttag atgcagtcat tatttctcac tatcatccag accatgtcgc
    25981 tgacttgggc gttttgcgtc attattttca gctttatcct aaacatcttt ggacgcccaa
    26041 agttttaccg atttacggtc atgaccaaga tacttatgag ttttcaaagt tgacacttga
    26101 tggtgtttct gaaggcagag cttataatgt caatggtctt gagcaaattg gatcttttga
    26161 cattactttt attaagacag tacatcctgt tgtttgctac gccatacgta ttgtggagcg
    26221 tacaactggt caaatttttg ttttcacagg tgatacgggt tattttgagg atttagataa
    26281 atttgccgca ggcgcggacc tctttttagc agatgtttac ctttacgaag gcaatgaaaa
    26341 ccacatcgct catttgacga ccaaagaagc tggacaaatc gctagtgcgg ctaaggtaaa
    26401 acgtctagtc ttgacccata tgccaccagt accgccagca ggcattgatc cagacaacca
    26461 tctagaaatc ctaagaagcc agactgaggc atactccaat ggcatccctg tggaattggc
    26521 tacacctcac aaatcatggc aaatcggtaa ctgctgatgg caggtttgac tcaggcagaa
    26581 aaagagtttt ttatgggaga agctctcaaa gaagctcagc tatcacttca aaaagaagag
    26641 attcctattg gctgtgttat cgttaaggac ggtcaaatca ttgggtgtgg tcataatgcg
    26701 cgtgaagagg aaaatcttgc catcatgcat gccgaaatta tggctatcaa tcaagcaaat
    26761 agaacacaag aaagttggcg tctgctggat tgtacgcttt ttgtcaccat tgagccttgc
    26821 attatgtgca gcggagccat tggtttagca cgtattccgc aggtcattta cggtgccaaa
    26881 aatgctaaat ttggtggggc tggttcctta tatgatatcc taactgatga gcggctcaat
    26941 catcgtgtag aagtagagag gggaattctg gaaaaagaat gtgctcaaat gatgcagagt
    27001 ttttttagat acaggagaac aaaatgaata caatcaccaa gccacaggaa tggctattat
    27061 cagctttttt gtttgcttta acattactct ttgttggtct gctagttttg aatttagatt
    27121 ttcaagcttg ggcttttgaa cgtcatca
//
