Select genomic region:
Overview
1.1
1.2
1.3
9.1
10.1
10.2
12.1
14.1
15.1

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_JAQCYD010000001.1 (Streptococcus mutans)

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 1.1 | RiPP-like | 50,052 | 77,199 |
Region 1.2 | RiPP-like | 177,387 | 187,617 |
Region 1.3 | terpene-precursor | 321,802 | 342,671 |

NZ_JAQCYD010000002.1 (Streptococcus mutans)

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 9.1 | T3PKS | 41,695 | 82,870 |

NZ_JAQCYD010000003.1 (Streptococcus mutans)

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 10.1 | RiPP-like | 108,534 | 127,479 |
Region 10.2 | lanthipeptide-class-ii | 143,958 | 170,990 | High | SmbA/SmbB | ribosomal:RiPP:Lanthipeptide

NZ_JAQCYD010000005.1 (Streptococcus mutans)

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 12.1 | RRE-containing,RaS-RiPP | 1 | 12,887 | High | tryglysin B | ribosomal:RiPP

NZ_JAQCYD010000007.1 (Streptococcus mutans)

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 14.1 | RiPP-like | 40,433 | 50,838 |

NZ_JAQCYD010000008.1 (Streptococcus mutans)

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 15.1 | NRPS,NRPS-like | 1 | 51,564 |

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 1.1 | RiPP-like | 50,052 | 77,199 |
Region 1.2 | RiPP-like | 177,387 | 187,617 |
Region 1.3 | terpene-precursor | 321,802 | 342,671 |
Region 9.1 | T3PKS | 41,695 | 82,870 |
Region 10.1 | RiPP-like | 108,534 | 127,479 |
Region 10.2 | lanthipeptide-class-ii | 143,958 | 170,990 | High | SmbA/SmbB | ribosomal:RiPP:Lanthipeptide
Region 12.1 | RRE-containing,RaS-RiPP | 1 | 12,887 | High | tryglysin B | ribosomal:RiPP
Region 14.1 | RiPP-like | 40,433 | 50,838 |
Region 15.1 | NRPS,NRPS-like | 1 | 51,564 |

No secondary metabolite regions were found in these records:
  NZ_JAQCYD010000010.1 (Streptococcus mutans)
  NZ_JAQCYD010000011.1 (Streptococcus mutans)
  NZ_JAQCYD010000012.1 (Streptococcus mutans)
  NZ_JAQCYD010000013.1 (Streptococcus mutans)
  NZ_JAQCYD010000014.1 (Streptococcus mutans)
  NZ_JAQCYD010000015.1 (Streptococcus mutans)
  NZ_JAQCYD010000016.1 (Streptococcus mutans)
  NZ_JAQCYD010000004.1 (Streptococcus mutans)
  NZ_JAQCYD010000006.1 (Streptococcus mutans)
  NZ_JAQCYD010000009.1 (Streptococcus mutans)

Compact view
NZ_JAQCYD010000001.1 - Region 1 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 50,052 - 77,199 nt. (total: 27,148 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: synthase
PGX70_RS00340: riboflavin biosynthesis protein RibD

smcogs
  SMCOG1240: riboflavin biosynthesis protein RibD

Transferases: transketolase
PGX70_RS00275: transketolase

smcogs
  SMCOG1204: transketolase

Hydrolases: synthase
PGX70_RS00340: riboflavin biosynthesis protein RibD

smcogs
  SMCOG1240: riboflavin biosynthesis protein RibD

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000617.5 |  | 0.50 | ribosomal | coagulin | Bacillus coagulans
BGC0000624.3 |  | 0.50 | ribosomal | salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide | Lactobacillus salivarius
BGC0002579.2 |  | 0.48 | ribosomal | carnobacteriocin XY | Carnobacterium maltaromaticum
BGC0000619.3 |  | 0.47 | ribosomal | gassericin T | Lactobacillus gasseri
BGC0001602.3 |  | 0.47 | ribosomal | gassericin-T | Lactobacillus gasseri
BGC0001388.3 |  | 0.47 | ribosomal | gassericin E | Lactobacillus gasseri
BGC0002577.2 |  | 0.44 | ribosomal | lactococcin G | Lactococcus lactis
BGC0001229.4 |  | 0.43 | ribosomal | SBI-06990 A1, SBI-06989 A2 | Streptomyces bingchenggensis BCW-1
BGC0000558.5 |  | 0.42 | ribosomal | sublancin 168 | Bacillus subtilis subsp. subtilis str. 168
BGC0001555.4 |  | 0.41 | ribosomal | colicin V | Escherichia coli chi7122

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000617.5 |  | 0.50 | ribosomal | coagulin | Bacillus coagulans
BGC0000624.3 |  | 0.50 | ribosomal | salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide | Lactobacillus salivarius
BGC0002579.2 |  | 0.48 | ribosomal | carnobacteriocin XY | Carnobacterium maltaromaticum
BGC0000619.3 |  | 0.47 | ribosomal | gassericin T | Lactobacillus gasseri
BGC0001602.3 |  | 0.47 | ribosomal | gassericin-T | Lactobacillus gasseri
BGC0001388.3 |  | 0.47 | ribosomal | gassericin E | Lactobacillus gasseri
BGC0002577.2 |  | 0.44 | ribosomal | lactococcin G | Lactococcus lactis
BGC0001229.4 |  | 0.43 | ribosomal | SBI-06990 A1, SBI-06989 A2 | Streptomyces bingchenggensis BCW-1
BGC0000558.5 |  | 0.42 | ribosomal | sublancin 168 | Bacillus subtilis subsp. subtilis str. 168
BGC0001555.4 |  | 0.41 | ribosomal | colicin V | Escherichia coli chi7122

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 24.27 out of 26.06
Confidence: strong
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.54 out of 26.06
Confidence: medium
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 22.69 out of 27.78
Confidence: medium
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 22.34 out of 27.78
Confidence: medium
SypG
Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 23.46 out of 29.25
Confidence: medium
FuR variant 1
Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 24.32 out of 29.38
Confidence: medium
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.88 out of 26.06
Confidence: medium
Additional weak hits (3):
FuR variant 1
Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 23.25 out of 29.38
Confidence: weak
MntR
Description: Manganese transport regulator
Species: Escherichia coli str. K-12 substr. MG1655
Score: 28.76 out of 39.62
Confidence: weak
DmdR1
Description: Iron(II)-dependent repressor
Species: Streptomyces coelicolor
Score: 22.99 out of 36.53
Confidence: weak
TFBS Finder
TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
CodY | Regulator of stationary phase and virulence in Gram-positive bacteria
FuR variant 1 | Ferric Uptake Regulator
MogR | Repressor of flagellar motility genes
SypG | Regulator of biofilm formation and host colonization

NZ_JAQCYD010000001.1 - Region 2 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 177,387 - 187,617 nt. (total: 10,231 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Hydrolases: back translocase hydrolase
PGX70_RS00915: GTP-binding protein LepA

smcogs
  SMCOG1190: GTP-binding protein LepA

PGX70_RS00950: hydrolase

smcogs
  SMCOG1179: hydrolase

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002436.2 |  | 0.34 | other (other) | coformycin | Streptomyces citricolor
BGC0002584.2 |  | 0.32 | ribosomal | azolemycin B, azolemycin A, azolemycin D, azolemycin C | Streptomyces sp. FXJ1.264
BGC0001591.4 |  | 0.27 | other (other) | fatty acid enol ester, N-tetradecanoyl tyrosine | uncultured bacterium CSLC2
BGC0000259.3 |  | 0.26 | PKS | prodigiosin | Serratia marcescens
BGC0000969.5 |  | 0.26 | NRPS, PKS | chondramide A | Chondromyces crocatus
BGC0000207.5 |  | 0.23 | PKS | chartreusin | Streptomyces chartreusis
BGC0002131.4 |  | 0.21 | NRPS, PKS, saccharide | aurantoside A | Chloroflexi bacterium TSY
BGC0002435.3 |  | 0.20 | other (other) | coformycin, aristeromycin | Micromonospora haikouensis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002436.2 |  | 0.34 | other (other) | coformycin | Streptomyces citricolor
BGC0002584.2 |  | 0.32 | ribosomal | azolemycin B, azolemycin A, azolemycin D, azolemycin C | Streptomyces sp. FXJ1.264
BGC0001591.4 |  | 0.27 | other (other) | fatty acid enol ester, N-tetradecanoyl tyrosine | uncultured bacterium CSLC2
BGC0000259.3 |  | 0.26 | PKS | prodigiosin | Serratia marcescens
BGC0000969.5 |  | 0.26 | NRPS, PKS | chondramide A | Chondromyces crocatus
BGC0000207.5 |  | 0.23 | PKS | chartreusin | Streptomyces chartreusis
BGC0002131.4 |  | 0.21 | NRPS, PKS, saccharide | aurantoside A | Chloroflexi bacterium TSY
BGC0002435.3 |  | 0.20 | other (other) | coformycin, aristeromycin | Micromonospora haikouensis

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
IolR
Description: Regulator of the inositol catabolism
Species: Caulobacter crescentus CB15
Score: 19.66 out of 23.79
Confidence: medium
ArcA
Description: Repressor of carbon oxidation
Species: Escherichia coli str. K-12 substr. MG1655
Score: 19.83 out of 21.55
Confidence: medium
SypG
Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 23.87 out of 29.25
Confidence: medium
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.34 out of 26.06
Confidence: medium
Additional weak hits (3):
HexR
Description: Glucose-responsive regulator
Species: Shewanella oneidensis MR-1
Score: 23.54 out of 31.73
Confidence: weak
CopR
Description: Copper-responsive regulator
Species: Lactococcus lactis subsp. lactis Il1403
Score: 24.41 out of 30.97
Confidence: weak
MatP
Description: Cell cycle regulator
Species: Escherichia coli str. K-12 substr. MG1655
Score: 22.29 out of 25.75
Confidence: weak
TFBS Finder
TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
ArcA | Repressor of carbon oxidation
IolR | Regulator of the inositol catabolism
MogR | Repressor of flagellar motility genes
SypG | Regulator of biofilm formation and host colonization

NZ_JAQCYD010000001.1 - Region 3 - terpene-precursor
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 321,802 - 342,671 nt. (total: 20,870 nt) Show pHMM detection rules used
terpene-precursor: (PT_FPPS_like and not PT_HPP)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Terpene
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Ligases: synthetase
PGX70_RS01665: Polyprenyl synthetase

smcogs
  SMCOG1182: Polyprenyl synthetase

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene-precursor | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002397.2 |  | 0.47 | terpene | astallatene | Arabidopsis thaliana
BGC0002400.2 |  | 0.44 | terpene | boleracene | Brassica oleracea var. oleracea
BGC0002398.2 |  | 0.38 | terpene | (-)-ent-quiannulatene | Arabidopsis thaliana
BGC0001456.3 |  | 0.30 | terpene | isorenieratene | Streptomyces argillaceus
BGC0000668.5 |  | 0.29 | other (other), terpene | 12-epi-hapalindole C isonitrile, 12-epi-hapalindole E, 12-epi-fischerindole U isonitrile, fischerindole L, 12-epi-fischerindole I isonitrile, welwitindolinone A isonitrile, welwitindolinone B isothiocyanate, welwitindolinone C isothiocyanate, N-methylwelwitindolinone C isothiocyanate, N-methylwelwitinsolinone C isonitrile, 3-epi-welwitindolinone B isothiocyanate, 3-(Z-2'-isocyanoethenyl)-indole | Hapalosiphon welwitschii UTEX B 1830
BGC0001756.3 |  | 0.28 | terpene | retigeranin, arathanatriene | Arabidopsis thaliana
BGC0001605.3 |  | 0.28 | terpene | gibberellin | Sinorhizobium fredii NGR234
BGC0001594.3 |  | 0.27 | other (other) | fischerindole L | Fischerella muscicola UTEX 1829
BGC0000648.3 |  | 0.27 | terpene | carotenoid | Myxococcus xanthus
BGC0001126.4 |  | 0.26 | other (other), terpene | 12-epi-hapalindole J isonitrile, ambiguine A isonitrile, ambiguine B isonitrile, ambiguine C isonitrile, ambiguine D isonitrile, ambiguine E isonitrile, ambiguine K isonitrile, ambiguine L isonitrile, ambiguine I isonitrile, ambiguine J isonitrile | Fischerella ambigua UTEX 1903

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002397.2 |  | 0.47 | terpene | astallatene | Arabidopsis thaliana
BGC0002400.2 |  | 0.44 | terpene | boleracene | Brassica oleracea var. oleracea
BGC0002398.2 |  | 0.38 | terpene | (-)-ent-quiannulatene | Arabidopsis thaliana
BGC0001456.3 |  | 0.30 | terpene | isorenieratene | Streptomyces argillaceus
BGC0000668.5 |  | 0.29 | other (other), terpene | 12-epi-hapalindole C isonitrile, 12-epi-hapalindole E, 12-epi-fischerindole U isonitrile, fischerindole L, 12-epi-fischerindole I isonitrile, welwitindolinone A isonitrile, welwitindolinone B isothiocyanate, welwitindolinone C isothiocyanate, N-methylwelwitindolinone C isothiocyanate, N-methylwelwitinsolinone C isonitrile, 3-epi-welwitindolinone B isothiocyanate, 3-(Z-2'-isocyanoethenyl)-indole | Hapalosiphon welwitschii UTEX B 1830
BGC0001756.3 |  | 0.28 | terpene | retigeranin, arathanatriene | Arabidopsis thaliana
BGC0001605.3 |  | 0.28 | terpene | gibberellin | Sinorhizobium fredii NGR234
BGC0001594.3 |  | 0.27 | other (other) | fischerindole L | Fischerella muscicola UTEX 1829
BGC0000648.3 |  | 0.27 | terpene | carotenoid | Myxococcus xanthus
BGC0001126.4 |  | 0.26 | other (other), terpene | 12-epi-hapalindole J isonitrile, ambiguine A isonitrile, ambiguine B isonitrile, ambiguine C isonitrile, ambiguine D isonitrile, ambiguine E isonitrile, ambiguine K isonitrile, ambiguine L isonitrile, ambiguine I isonitrile, ambiguine J isonitrile | Fischerella ambigua UTEX 1903

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Detailed terpene predictions
Detailed information for terpene domains. Shows possible products of a terpene cluster and lists the subtype and expected reactions for each terpene-related domain.
Product predictions:

Class | Subclass | Product name | Chain length | Initial cyclisations | Functional groups
--- | --- | --- | --- | --- | ---
sesquiterpene precursor |  | FPP | C15 | acyclic | PP

Genes with terpene domains:
PGX70_RS01665: PT_FPPS_like
Domain 1 (25 - 283): Prenyltransferase; Farnesyl diphosphate synthase like
Subtype: Farnesyl diphosphate synthase, bacterial

Reactions:
  IPP, DMAPP → FPP

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
CcpA
Description: Catabolite control protein A
Species: Streptococcus & Clostridium sp.
Score: 19.05 out of 20.97
Confidence: strong
ToxT
Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.57 out of 18.57
Confidence: strong
AbrC3
Description: Antibiotic production activator
Species: Streptomyces coelicolor
Score: 15.51 out of 18.16
Confidence: strong
FuR variant 1
Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 25.33 out of 29.38
Confidence: medium
FuR variant 1
Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 24.49 out of 29.38
Confidence: medium
Additional weak hits (2):
LuxO
Description: Repressor of luminescence
Species: Vibrio campbellii ATCC BAA-1116
Score: 20.68 out of 26.12
Confidence: weak
CopR
Description: Copper-responsive regulator
Species: Lactococcus lactis subsp. lactis Il1403
Score: 23.60 out of 30.97
Confidence: weak
Terpene
TFBS Finder
Glossary
Glossary showing acronyms and their full names.

Acronym | Full name
--- | ---
DMAPP | Dimethylallyl diphosphate
FPP | Farnesyl diphosphate
IPP | Isopentenyl diphosphate
PP | Diphosphate

TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
AbrC3 | Antibiotic production activator
CcpA | Catabolite control protein A
FuR variant 1 | Ferric Uptake Regulator
ToxT | Regulator of MSHA biosynthesis

NZ_JAQCYD010000002.1 - Region 1 - T3PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 41,695 - 82,870 nt. (total: 41,176 nt) Show pHMM detection rules used
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
TFBS Finder
NRPS/PKS domains
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: dehydrogenase reductase
PGX70_RS03120: alkyl hydroperoxide reductase/ Thiol specific

smcogs
  SMCOG1196: alkyl hydroperoxide reductase/ Thiol specific

PGX70_RS03205: hydroxymethylglutaryl-CoA reductase

smcogs
  SMCOG1187: hydroxymethylglutaryl-CoA reductase

PGX70_RS03290: acyl-CoA dehydrogenase

smcogs
  SMCOG1006: acyl-CoA dehydrogenase

Transferases: aminotransferase
PGX70_RS03255: aminotransferase

smcogs
  SMCOG1019: aminotransferase

Ligases: synthase
PGX70_RS03210: hydroxymethylglutaryl-CoA synthase

smcogs
  SMCOG1043: hydroxymethylglutaryl-CoA synthase

Translocases: permease
PGX70_RS03245: phenylalanine-specific permease

smcogs
  SMCOG1038: phenylalanine-specific permease

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | T3PKS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000513.3 |  | 0.50 | ribosomal | Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3 | Saccharopolyspora erythraea NRRL 2338
BGC0000883.5 |  | 0.44 | other (other) | arginomycin | Streptomyces arginensis
BGC0002561.3 |  | 0.44 | other (other) | phenazine SA, phenazine SB, phenazine SC | Streptomyces sp.
BGC0000557.5 |  | 0.44 | ribosomal | streptococcin A-FF22 | Streptococcus pyogenes
BGC0001788.3 |  | 0.44 | ribosomal | suicin 65 | Streptococcus suis
BGC0000547.5 |  | 0.44 | ribosomal | salivaricin 9 | Streptococcus salivarius
BGC0000521.3 |  | 0.44 | ribosomal | lacticin 481 | Lactococcus lactis subsp. lactis
BGC0002294.3 |  | 0.44 | other (other) | streptozotocin | Streptomyces achromogenes subsp. streptozoticus
BGC0000526.5 |  | 0.43 | ribosomal | macedocin | Streptococcus macedonicus
BGC0000546.3 |  | 0.43 | ribosomal | SAL-2242 | Streptomyces albidoflavus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000513.3 |  | 0.50 | ribosomal | Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3 | Saccharopolyspora erythraea NRRL 2338
BGC0000883.5 |  | 0.44 | other (other) | arginomycin | Streptomyces arginensis
BGC0002561.3 |  | 0.44 | other (other) | phenazine SA, phenazine SB, phenazine SC | Streptomyces sp.
BGC0000557.5 |  | 0.44 | ribosomal | streptococcin A-FF22 | Streptococcus pyogenes
BGC0001788.3 |  | 0.44 | ribosomal | suicin 65 | Streptococcus suis
BGC0000547.5 |  | 0.44 | ribosomal | salivaricin 9 | Streptococcus salivarius
BGC0000521.3 |  | 0.44 | ribosomal | lacticin 481 | Lactococcus lactis subsp. lactis
BGC0002294.3 |  | 0.44 | other (other) | streptozotocin | Streptomyces achromogenes subsp. streptozoticus
BGC0000526.5 |  | 0.43 | ribosomal | macedocin | Streptococcus macedonicus
BGC0000546.3 |  | 0.43 | ribosomal | SAL-2242 | Streptomyces albidoflavus

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
GnfM
Description: Regulator of nitrogen-fixation genes
Species: Geobacter sulfurreducens PCA
Score: 21.99 out of 27.55
Confidence: medium
CcpA
Description: Catabolite control protein A
Species: Streptococcus & Clostridium sp.
Score: 19.13 out of 20.97
Confidence: strong
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.90 out of 26.06
Confidence: medium
PerR
Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 25.31 out of 28.14
Confidence: medium
ZuR variant 1
Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 24.52 out of 28.19
Confidence: strong
Additional weak hits (7):
MatP
Description: Cell cycle regulator
Species: Escherichia coli str. K-12 substr. MG1655
Score: 19.71 out of 25.75
Confidence: weak
HexR
Description: Glucose-responsive regulator
Species: Shewanella oneidensis MR-1
Score: 23.96 out of 31.73
Confidence: weak
SypG
Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 22.38 out of 29.25
Confidence: weak
LuxO
Description: Repressor of luminescence
Species: Vibrio campbellii ATCC BAA-1116
Score: 21.58 out of 26.12
Confidence: weak
VqsM
Description: Regulator of quorum-sensing signalling systems
Species: Pseudomonas aeruginosa PAO1
Score: 16.71 out of 20.47
Confidence: weak
ZuR variant 2
Description: Zinc-responsive repressor
Species: Pseudomonas protegens Pf-5
Score: 26.34 out of 33.14
Confidence: weak
DasR
Description: N-acetylglucosamine dependent repressor
Species: Streptomyces coelicolor
Score: 20.84 out of 27.04
Confidence: weak
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
TFBS Finder
TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
CcpA | Catabolite control protein A
GnfM | Regulator of nitrogen-fixation genes
MogR | Repressor of flagellar motility genes
PerR | Peroxide regulator
ZuR variant 1 | Zinc-responsive repressor

NZ_JAQCYD010000003.1 - Region 1 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 108,534 - 127,479 nt. (total: 18,946 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
No tailoring functions detected.
Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000624.3 |  | 0.41 | ribosomal | salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide | Lactobacillus salivarius
BGC0002579.2 |  | 0.39 | ribosomal | carnobacteriocin XY | Carnobacterium maltaromaticum
BGC0001291.3 |  | 0.34 | ribosomal | enterocin NKR-5-3B | Enterococcus faecium
BGC0000540.5 |  | 0.33 | ribosomal | paenibacillin | Paenibacillus polymyxa OSY-DF
BGC0000494.5 |  | 0.32 | ribosomal | uberolysin | Streptococcus uberis
BGC0002667.2 |  | 0.24 | ribosomal | estericin A | Clostridium estertheticum
BGC0000498.5 |  | 0.23 | ribosomal | bovicin HJ50 | Streptococcus equinus
BGC0000561.5 |  | 0.23 | ribosomal | thermophilin 1277 | Streptococcus thermophilus
BGC0000503.5 |  | 0.21 | ribosomal | cinnamycin | Streptomyces cinnamoneus
BGC0000164.5 |  | 0.20 | PKS | tetronomycin | Streptomyces sp. NRRL 11266

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000624.3 |  | 0.41 | ribosomal | salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide | Lactobacillus salivarius
BGC0002579.2 |  | 0.39 | ribosomal | carnobacteriocin XY | Carnobacterium maltaromaticum
BGC0001291.3 |  | 0.34 | ribosomal | enterocin NKR-5-3B | Enterococcus faecium
BGC0000540.5 |  | 0.33 | ribosomal | paenibacillin | Paenibacillus polymyxa OSY-DF
BGC0000494.5 |  | 0.32 | ribosomal | uberolysin | Streptococcus uberis
BGC0002667.2 |  | 0.24 | ribosomal | estericin A | Clostridium estertheticum
BGC0000498.5 |  | 0.23 | ribosomal | bovicin HJ50 | Streptococcus equinus
BGC0000561.5 |  | 0.23 | ribosomal | thermophilin 1277 | Streptococcus thermophilus
BGC0000503.5 |  | 0.21 | ribosomal | cinnamycin | Streptomyces cinnamoneus
BGC0000164.5 |  | 0.20 | PKS | tetronomycin | Streptomyces sp. NRRL 11266

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
CcpA
Description: Catabolite control protein A
Species: Streptococcus & Clostridium sp.
Score: 19.35 out of 20.97
Confidence: strong
ToxT
Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.57 out of 18.57
Confidence: strong
SypG
Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 24.91 out of 29.25
Confidence: medium
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 22.99 out of 27.78
Confidence: medium
LexA variant 2
Description: Repressor of DNA damage response
Species: Bacillus subtilis subsp. subtilis str. 168
Score: 21.00 out of 24.78
Confidence: medium
AbrC3
Description: Antibiotic production activator
Species: Streptomyces coelicolor
Score: 17.05 out of 18.16
Confidence: strong
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 23.01 out of 26.06
Confidence: medium
Additional weak hits (1):
CelR
Description: Cellobiose uptake repressor
Species: Streptomyces coelicolor
Score: 23.18 out of 30.11
Confidence: weak
TFBS Finder
TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
AbrC3 | Antibiotic production activator
CcpA | Catabolite control protein A
CodY | Regulator of stationary phase and virulence in Gram-positive bacteria
LexA variant 2 | Repressor of DNA damage response
MogR | Repressor of flagellar motility genes
SypG | Regulator of biofilm formation and host colonization
ToxT | Regulator of MSHA biosynthesis

NZ_JAQCYD010000003.1 - Region 2 - lanthipeptide-class-ii
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 143,958 - 170,990 nt. (total: 27,033 nt) Show pHMM detection rules used
lanthipeptide-class-ii: cds(LANC_like and DUF4135)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Lanthipeptides
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Hydrolases: deacetylase
PGX70_RS05490: acetylornithine deacetylase

smcogs
  SMCOG1247: acetylornithine deacetylase

Lyases: cyclase
PGX70_RS05530: lanthionine synthetase C family protein

smcogs
  SMCOG1070: lanthionine synthetase C family protein

PGX70_RS05545: lanthionine synthetase C family protein

smcogs
  SMCOG1070: lanthionine synthetase C family protein

Ligases: synthase
PGX70_RS05585: pseudouridine synthase

smcogs
  SMCOG1279: pseudouridine synthase

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | lanthipeptide-class-ii | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000552.3 |  | 0.99 | ribosomal | SmbA, SmbB | Streptococcus mutans
BGC0000497.3 |  | 0.85 | ribosomal | BHT-Aα, BHT-Aβ | Streptococcus ratti
BGC0000626.3 |  | 0.54 | ribosomal | thuricin | Bacillus thuringiensis
BGC0000623.3 |  | 0.53 | ribosomal | plantaricin W α, plantaricin W β | Lactobacillus plantarum
BGC0000525.5 |  | 0.53 | ribosomal | lichenicidin VK21 A1, lichenicidin VK21 A2 | Bacillus licheniformis
BGC0001311.5 |  | 0.52 | ribosomal | flavecins | Ruminococcus flavefaciens FD-1
BGC0002698.2 |  | 0.52 | ribosomal | phaeornamide | Pseudophaeobacter arcticus DSM 23566
BGC0001229.4 |  | 0.52 | ribosomal | SBI-06990 A1, SBI-06989 A2 | Streptomyces bingchenggensis BCW-1
BGC0000521.3 |  | 0.51 | ribosomal | lacticin 481 | Lactococcus lactis subsp. lactis
BGC0000517.4 |  | 0.51 | ribosomal | haloduracin β, haloduracin α | Bacillus halodurans C-125

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000552.3 |  | 0.99 | ribosomal | SmbA, SmbB | Streptococcus mutans
BGC0000497.3 |  | 0.85 | ribosomal | BHT-Aα, BHT-Aβ | Streptococcus ratti
BGC0000626.3 |  | 0.54 | ribosomal | thuricin | Bacillus thuringiensis
BGC0000623.3 |  | 0.53 | ribosomal | plantaricin W α, plantaricin W β | Lactobacillus plantarum
BGC0000525.5 |  | 0.53 | ribosomal | lichenicidin VK21 A1, lichenicidin VK21 A2 | Bacillus licheniformis
BGC0001311.5 |  | 0.52 | ribosomal | flavecins | Ruminococcus flavefaciens FD-1
BGC0002698.2 |  | 0.52 | ribosomal | phaeornamide | Pseudophaeobacter arcticus DSM 23566
BGC0001229.4 |  | 0.52 | ribosomal | SBI-06990 A1, SBI-06989 A2 | Streptomyces bingchenggensis BCW-1
BGC0000521.3 |  | 0.51 | ribosomal | lacticin 481 | Lactococcus lactis subsp. lactis
BGC0000517.4 |  | 0.51 | ribosomal | haloduracin β, haloduracin α | Bacillus halodurans C-125

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.
Location:
Identifier
Identity
Coverage
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Lanthipeptide predictions
Shows the possible core peptides for each biosynthetic enzyme.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.

#### Lanthipeptide(s) for PGX70_RS05530

PGX70_RS05515
Leader:
MKEIQKAGLQEELSILMDDANNLEQLTAG
Core:
I G T T V V N S T F S I V L G N K G Y I C T V T V E C M R N C S K
Core with dehydrations:
I G Dhb Dhb V V N Dha Dhb F Dha I V L G N K G Y I Cys Dhb V Dhb V E Cys M R N Cys Dha K

#### antiSMASH-DB 4.0 matches for PGX70_RS05515

100.0%
NC_018089.1 and 11 others:
NC_018089.1 Lanthipeptides: SMUGS5_RS08725_lanthipeptide NZ_CP044493.1 Lanthipeptides: FSA40_RS09065_lanthipeptide NZ_CP044493.1 Lanthipeptides: FSA40_RS09065_lanthipeptide NZ_CP050270.1 Lanthipeptides: HB753_RS00325_lanthipeptide NZ_CP050270.1 Lanthipeptides: HB753_RS00325_lanthipeptide NZ_JADPAN010000004.1 Lanthipeptides: I4U28_RS03985_lanthipeptide NZ_JADPAN010000004.1 Lanthipeptides: I4U28_RS03985_lanthipeptide NZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS08120_lanthipeptide NZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS08120_lanthipeptide NZ_JAQCYD010000003.1 Lanthipeptides: PGX70_RS05515_lanthipeptide NZ_JAQCYD010000003.1 Lanthipeptides: PGX70_RS05515_lanthipeptide
Lanthipeptides: SMUGS5_RS08725_lanthipeptide
1
I G T T V V N S T F S I V L G N K G Y I C T V T V E C M R N C S K
33
I G T T V V N S T F S I V L G N K G Y I C T V T V E C M R N C S K
1
I G T T V V N S T F S I V L G N K G Y I C T V T V E C M R N C S K
33
93.9%
NZ_CP043405.1 and 1 other:
NZ_CP043405.1 Lanthipeptides: FY406_RS04355_lanthipeptide
Lanthipeptides: FY406_RS04355_lanthipeptide
1
I G T T V V N S T F S I V L G N K G Y I C T V T V E C M R N C S
32
I G T T V V N S T F S I V L G N K G Y I C T V T V E C M R N C
1
I G T T V V N S T F S I V L G N K G Y I C T V T V E C M R N C Q
32
50.0%
NZ_BMVL01000013.1 and 1 other:
NZ_BMVL01000013.1 Lanthipeptides: IE257_RS28650_lanthipeptide
Lanthipeptides: IE257_RS28650_lanthipeptide
1
I G T T V V N S T F S I V L G N K G Y I C T V T V E C M R N C S K
33
I T V + S L G N G++C T V T V E C +N C +
2
I F E T V T Y T V A S W A L G N N G H L C T V T V E C Q K N C Q R
34
with 101 more sequence matches
Only the first 10 are displayed here.
48.6%
NZ_QKTG01000020.1 and 1 other:
NZ_QKTG01000020.1 Lanthipeptides: DEI99_RS16920_lanthipeptide
Lanthipeptides: DEI99_RS16920_lanthipeptide
1
I G T T V V N S T---F S I V L G N K G Y I C T V T V E C M R N C
31
I G T T V + S L G N G C T T V E C N C
3
I G T T V T T L S C Y G V S W A L G N D G N F C T A T V E C Q S N C
36
48.5%
NZ_BMMP01000005.1 and 3 others:
NZ_BMMP01000005.1 Lanthipeptides: IEY56_RS28370_lanthipeptide NZ_FMHJ01000003.1 Lanthipeptides: H181DRAFT_RS07545_lanthipeptide NZ_FMHJ01000003.1 Lanthipeptides: H181DRAFT_RS07545_lanthipeptide
Lanthipeptides: IEY56_RS28370_lanthipeptide
8
S T F S I--V L G N K G Y I C T V T V E C M R N C S
32
+T F S+ V L G N G C T+T V E C N C+
4
N T F S L S D V L G N T G G W C T L T V E C Q P N C N
30
45.5%
NZ_CP016795.1 and 5 others:
NZ_CP016795.1 Lanthipeptides: BC342_RS18360_lanthipeptide NZ_CP036534.1 Lanthipeptides: EZV63_RS18960_lanthipeptide NZ_CP036534.1 Lanthipeptides: EZV63_RS18960_lanthipeptide NZ_CP094676.1 Lanthipeptides: L6J92_RS01495_lanthipeptide NZ_CP094676.1 Lanthipeptides: L6J92_RS01495_lanthipeptide
Lanthipeptides: BC342_RS18360_lanthipeptide
8
S T F S I--V L G N K G Y I C T V T V E C M R N C S
32
+T F S+ L G N G C T+T E C N C S
4
N T F S L S D A L G N H G G W C T L T K E C Q P N C S
30
45.5%
NZ_CP047419.1 and 3 others:
NZ_CP047419.1 Lanthipeptides: GTU71_RS12805_lanthipeptide NZ_PSTO01000045.1 Lanthipeptides: C5C10_RS15590_lanthipeptide NZ_PSTO01000045.1 Lanthipeptides: C5C10_RS15590_lanthipeptide
Lanthipeptides: GTU71_RS12805_lanthipeptide
9
T F S I V L G N K G Y I C T V T V E C M R N C
31
T S V L G N+G C T+T V E C N C
7
T L S N V L G N Q G G W C T L T V E C Q P N C
29
45.5%
NZ_KV795763.1 and 2 others:
NZ_KV804818.1 Lanthipeptides: allorf_114850_115005_lanthipeptide NZ_KV804818.1 Lanthipeptides: allorf_114850_115005_lanthipeptide
Lanthipeptides: allorf_248182_248337_lanthipeptide
4
T V V N S T F S I V L G N K G Y I C T V T V E C M R N C S
32
T +S V+G N+G +C T V T V E C M C
1
T A F P G W Y S K V I G N R G R V C T V T V E C M S V C Q
29
44.1%
NZ_BQXZ01000001.1 and 1 other:
NZ_BQXZ01000001.1 Lanthipeptides: OCU69_RS05000_lanthipeptide
Lanthipeptides: OCU69_RS05000_lanthipeptide
9
T F S I V L G N K G Y I C T V T V E C M R N C S K
33
T S+ +G N K G +C T T+E C N C S K
10
T L S V Y M G N K G S V C T W T I E C Q S N C S K
34
42.4%
NC_002570.2 and 3 others:
NC_002570.2 Lanthipeptides: AYT26_RS02480_lanthipeptide NZ_CP040441.1 Lanthipeptides: FED51_RS02600_lanthipeptide NZ_CP040441.1 Lanthipeptides: FED51_RS02600_lanthipeptide
Lanthipeptides: AYT26_RS02480_lanthipeptide
11
S I V L G N K G Y I C T V T V E C M R N C S
32
S L G N K G C T+T V E C M +C+
11
S C R L G N K G A Y C T L T V E C M P S C N
32
42.4%
NC_006322.1 and 7 others:
NC_006322.1 Lanthipeptides: BLI_RS20295_lanthipeptide NZ_CP033218.1 Lanthipeptides: D9Y32_RS07805_lanthipeptide NZ_CP033218.1 Lanthipeptides: D9Y32_RS07805_lanthipeptide NZ_LQYL01000021.1 Lanthipeptides: B4090_RS08835_lanthipeptide NZ_LQYL01000021.1 Lanthipeptides: B4090_RS08835_lanthipeptide NZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11865_lanthipeptide NZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11865_lanthipeptide
Lanthipeptides: BLI_RS20295_lanthipeptide
10
F S I V L G N K G Y I C T V T V E C M R N C S
32
S L G N G Y+C T V T E C M +C+
10
L S K P L G N N G Y L C T V T K E C M P S C N
32
42.4%
NC_018499.1 and 10 others:
NC_018499.1 Lanthipeptides: BCK_RS27855_lanthipeptide NC_018499.1 Lanthipeptides: BCK_RS27850_lanthipeptide NC_018499.1 Lanthipeptides: BCK_RS27860_lanthipeptide NC_018499.1 Lanthipeptides: BCK_RS27855_lanthipeptide NC_018499.1 Lanthipeptides: BCK_RS27850_lanthipeptide NZ_JAOPQW010000026.1 Lanthipeptides: OCD10_RS25275_lanthipeptide NZ_JAOPQW010000026.1 Lanthipeptides: OCD10_RS25270_lanthipeptide NZ_MLKL01000042.1 Lanthipeptides: BKK45_RS27570_lanthipeptide NZ_MLKL01000042.1 Lanthipeptides: BKK45_RS27565_lanthipeptide NZ_MLKL01000042.1 Lanthipeptides: BKK45_RS27560_lanthipeptide
Lanthipeptides: BCK_RS27860_lanthipeptide
5
V V N S T F S I V L G N K G Y I C T V T V E C M R N C S
32
V S L G N K G C T+T E C M +C+
5
V T P E G L S S W L G N K G G Y C T L T K E C M P S C N
32
42.4%
NZ_AKXV01000031.1 and 4 others:
NZ_AKXV01000031.1 Lanthipeptides: Y19_RS0109895_lanthipeptide NZ_JABBGE010000004.1 Lanthipeptides: HHL19_RS13545_lanthipeptide NZ_LMEI01000006.1 Lanthipeptides: ASC82_RS06140_lanthipeptide NZ_LMEI01000006.1 Lanthipeptides: ASC82_RS06140_lanthipeptide
Lanthipeptides: Y19_RS0109895_lanthipeptide
8
S T F S I--V L G N K G Y I C T V T V E C M R N C S
32
+T F S+ L G N+G C T+T E C N C+
4
N T F S L S D F L G N Q G G W C T L T K E C Q P N C N
30

#### MIBiG 4.0 matches for PGX70_RS05515

42.4%
BGC0000517.4 (BAB04173.1):
Lanthipeptide: haloduracin β or haloduracin α
11
S I V L G N K G Y I C T V T V E C M R N C S
32
S L G N K G C T+T V E C M +C+
7
S C R L G N K G A Y C T L T V E C M P S C N
28
42.4%
BGC0002110.3 (QKV49893.1):
Lanthipeptide: birimositide
8
S T F S I--V L G N K G Y I C T V T V E C M R N C S
32
+T F S+ L G N G C T+T E C N C+
4
N T F S L S N A L G N N G G W C T L T K E C Q P N C N
30
15.4%
BGC0001229.4 (SBI_06990):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
21
C T V T V E C M R N C
31
C T++ E C N C
28
C T L S K E C Q P N C
38
PGX70_RS05520
Leader:
MKSNLLKINNVTEMEKNMVTLIKDEDMELAGG
Core:
S T P A C A I G V V G I T V A V T G I S T A C T S R C I N K
Core with dehydrations:
Dha Dhb P A Cys A I G V V G I Dhb V A V Dhb G I Dha Dhb A Cys Dhb Dha R Cys I N K

#### antiSMASH-DB 4.0 matches for PGX70_RS05520

100.0%
NC_018089.1 and 13 others:
NC_018089.1 Lanthipeptides: SMUGS5_RS08730_lanthipeptide NZ_CP043405.1 Lanthipeptides: FY406_RS04350_lanthipeptide NZ_CP043405.1 Lanthipeptides: FY406_RS04350_lanthipeptide NZ_CP044493.1 Lanthipeptides: FSA40_RS09070_lanthipeptide NZ_CP044493.1 Lanthipeptides: FSA40_RS09070_lanthipeptide NZ_CP050270.1 Lanthipeptides: HB753_RS00320_lanthipeptide NZ_CP050270.1 Lanthipeptides: HB753_RS00320_lanthipeptide NZ_JADPAN010000004.1 Lanthipeptides: I4U28_RS03990_lanthipeptide NZ_JADPAN010000004.1 Lanthipeptides: I4U28_RS03990_lanthipeptide NZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS08125_lanthipeptide NZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS08125_lanthipeptide NZ_JAQCYD010000003.1 Lanthipeptides: PGX70_RS05520_lanthipeptide NZ_JAQCYD010000003.1 Lanthipeptides: PGX70_RS05520_lanthipeptide
Lanthipeptides: SMUGS5_RS08730_lanthipeptide
1
S T P A C A I G V V G I T V A V T G I S T A C T S R C I N K
30
S T P A C A I G V V G I T V A V T G I S T A C T S R C I N K
1
S T P A C A I G V V G I T V A V T G I S T A C T S R C I N K
30
43.3%
NZ_CP034414.1 and 1 other:
NZ_CP034414.1 Lanthipeptides: EI692_RS18435_lanthipeptide
Lanthipeptides: EI692_RS18435_lanthipeptide
2
T P A C A I G V V G I T V A V T G I S T A C T S R C
27
T P A +I V G T S T A C T C
2
T P A I S I L V S G F I S T N T C P S T A C T R A C
27
40.6%
NZ_NUML01000015.1:
Lanthipeptides: COD66_RS20140_lanthipeptide
1
S T P A C A I G V V G I T V A V T G I S T A C T S R C
27
+T P A V V G I+V + +T C T S+C
7
T T P A T P T I V V G I S V G L C P-T T K C T S K C
32
with 19 more sequence matches
Only the first 10 are displayed here.
40.0%
NZ_JAMXMK010000009.1:
Lanthipeptides: NGM22_RS28125_lanthipeptide
1
S T P A C A I G V V G I T V A V T G I S T A C T S R C
27
S T P A C A V G+T+A G C
7
S T P A C A---V G V T I A A W G A H K L S Y W N C
30
39.4%
NC_015215.1 and 5 others:
NC_015215.1 Lanthipeptides: SGGBAA2069_RS00700_lanthipeptide NZ_JAKUYO010000004.1 Lanthipeptides: MK556_RS09790_lanthipeptide NZ_JAKUYO010000004.1 Lanthipeptides: MK556_RS09790_lanthipeptide NZ_JAMDHZ010000003.1 Lanthipeptides: M5Q10_RS05355_lanthipeptide NZ_JAMDHZ010000003.1 Lanthipeptides: M5Q10_RS05355_lanthipeptide
Lanthipeptides: SGGBAA2069_RS00700_lanthipeptide
1
S T P A C A---I G V V G I T V A V T G I S T A C T S R C I N
29
S T P C A + + A+ I+T A C T+R C +
1
S T P G C A W A A V S A I S T V S A L F Q I T T A C T T R C Y H
32
37.5%
NZ_CP036019.1 and 1 other:
NZ_CP036019.1 Lanthipeptides: EXW52_RS27205_lanthipeptide
Lanthipeptides: EXW52_RS27205_lanthipeptide
1
S T P A C A I G V V G I T V A V T G I S T A C T S R C
27
+T P A V V I+V + +T C T S+C
7
T T P A T P T I V V A I S V G L C P-T T K C T S K C
32
31.4%
NZ_CM000721.1 and 9 others:
NZ_CP015591.1 Lanthipeptides: A7A70_RS27555_lanthipeptide NZ_CP078085.1 Lanthipeptides: KU891_RS29360_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptide NZ_NUBO01000052.1 Lanthipeptides: CN575_RS29785_lanthipeptide NZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptide NZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptide
Lanthipeptides: BCERE0010_RS29355_lanthipeptide
9
V V G I T V A V T G---I S T A C T S R C
27
++G T+A V T +T C T S R C
14
I I G A T I A V T A S L C P T T K C T S R C
35
31.0%
NZ_NTSR01000029.1 and 1 other:
NZ_NTSR01000029.1 Lanthipeptides: CN358_RS25165_lanthipeptide
Lanthipeptides: CN358_RS25165_lanthipeptide
5
C A I G--V V G I T V A V T G I S------T A C T S R C
27
C A+G V G I T+ S +A C+S R C
11
C A V G G A T V G I T I Y T F D R S H Q S C P T S A C S S R C
41
30.0%
NZ_CP084530.1 and 1 other:
NZ_CP084530.1 Lanthipeptides: LDO05_RS02090_lanthipeptide
Lanthipeptides: LDO05_RS02090_lanthipeptide
9
V V G I T V A V T G I S T A C T S R C
27
+ G+ A S T A C T S+C
10
I C G V A S A A F C P S T A C T S K C
28
26.7%
NC_014622.2 and 5 others:
NC_017542.1 Lanthipeptides: PPM_RS22280_lanthipeptide NZ_CP029370.1 Lanthipeptides: DI243_RS20990_lanthipeptide NZ_CP034141.1 Lanthipeptides: EGM68_RS21685_lanthipeptide NZ_PNXP01000027.1 Lanthipeptides: C1I59_RS20700_lanthipeptide NZ_POVS01000032.1 Lanthipeptides: C1T21_RS26405_lanthipeptide
Lanthipeptides: PPSC2_RS50140_lanthipeptide
1
S T P A C A I G V V G I T V A V
16
S T P + V+G+T V V
7
S T P T I T V T V I G V T V L V
22
26.7%
NZ_CM000752.1 and 15 others:
NZ_CM000752.1 Sactipeptides: BTHUR0007_RS37430_sactipeptide NZ_JABGBR020000007.1 Sactipeptides: HOV72_RS15955_sactipeptide NZ_JABGBR020000007.1 Sactipeptides: HOV72_RS15950_sactipeptide NZ_JYPH01000039.1 Sactipeptides: TU52_RS33370_sactipeptide NZ_JYPH01000039.1 Sactipeptides: TU52_RS33365_sactipeptide NZ_NJPZ01000025.1 Sactipeptides: CE087_RS29070_sactipeptide NZ_NJPZ01000025.1 Sactipeptides: CE087_RS29065_sactipeptide NZ_NJPZ01000025.1 Sactipeptides: CE087_RS29060_sactipeptide NZ_NUBO01000020.1 Sactipeptides: CN575_RS31360_sactipeptide NZ_NUBO01000020.1 Sactipeptides: CN575_RS31355_sactipeptide NZ_NUBO01000020.1 Sactipeptides: CN575_RS31350_sactipeptide NZ_NUUQ01000016.1 Sactipeptides: COI65_RS30820_sactipeptide NZ_NUUQ01000016.1 Sactipeptides: COI65_RS30815_sactipeptide NZ_NUUQ01000016.1 Sactipeptides: COI65_RS30810_sactipeptide NZ_NUXK01000018.1 Sactipeptides: COJ27_RS31850_sactipeptide
Sactipeptides: BTHUR0007_RS37435_sactipeptide
4
A C A I G V V G I T V A V T G I S T A
22
A C++ ++ + A T G S T A
11
A C S V E L L N L V T A A T G A S T A
29
26.7%
NZ_JAQQWR010000009.1:
Lanthipeptides: PQ473_RS20135_lanthipeptide
1
S T P A C A I G V V G I T V A V T G I S
20
+T P A C G + I T+ V ++
7
T T P A C I Y G G I A I T I G V V S V A
26
25.6%
NZ_CP009280.1 and 1 other:
NZ_CP009280.1 Lanthipeptides: P40081_RS37160_lanthipeptide
Lanthipeptides: P40081_RS37160_lanthipeptide
5
C A I G V V G I T V A V T G I S T A C T S R C
27
C I G V I+ + +T C T S+C
18
C V I G A V D I S A N L C P-T T K C T S K C
39

#### MIBiG 4.0 matches for PGX70_RS05520

16.7%
BGC0002110.3 (QKV49894.1):
Lanthipeptide: birimositide
20
S T A C T S R C
27
+T C T S+C
19
T T K C T S K C
26
16.2%
BGC0001229.4 (SBI_06989):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
20
S T A C T S R C
27
+T C T S R C
30
T T K C T S R C
37

#### Lanthipeptide(s) for PGX70_RS05545

PGX70_RS05515
Leader:
MKEIQKAGLQEELSILMDDANNLEQLTAG
Core:
I G T T V V N S T F S I V L G N K G Y I C T V T V E C M R N C S K
Core with dehydrations:
I G Dhb Dhb V V N Dha Dhb F Dha I V L G N K G Y I Cys Dhb V Dhb V E Cys M R N Cys Dha K

#### antiSMASH-DB 4.0 matches for PGX70_RS05515

100.0%
NC_018089.1 and 11 others:
NC_018089.1 Lanthipeptides: SMUGS5_RS08725_lanthipeptide NZ_CP044493.1 Lanthipeptides: FSA40_RS09065_lanthipeptide NZ_CP044493.1 Lanthipeptides: FSA40_RS09065_lanthipeptide NZ_CP050270.1 Lanthipeptides: HB753_RS00325_lanthipeptide NZ_CP050270.1 Lanthipeptides: HB753_RS00325_lanthipeptide NZ_JADPAN010000004.1 Lanthipeptides: I4U28_RS03985_lanthipeptide NZ_JADPAN010000004.1 Lanthipeptides: I4U28_RS03985_lanthipeptide NZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS08120_lanthipeptide NZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS08120_lanthipeptide NZ_JAQCYD010000003.1 Lanthipeptides: PGX70_RS05515_lanthipeptide NZ_JAQCYD010000003.1 Lanthipeptides: PGX70_RS05515_lanthipeptide
Lanthipeptides: SMUGS5_RS08725_lanthipeptide
1
I G T T V V N S T F S I V L G N K G Y I C T V T V E C M R N C S K
33
I G T T V V N S T F S I V L G N K G Y I C T V T V E C M R N C S K
1
I G T T V V N S T F S I V L G N K G Y I C T V T V E C M R N C S K
33
93.9%
NZ_CP043405.1 and 1 other:
NZ_CP043405.1 Lanthipeptides: FY406_RS04355_lanthipeptide
Lanthipeptides: FY406_RS04355_lanthipeptide
1
I G T T V V N S T F S I V L G N K G Y I C T V T V E C M R N C S
32
I G T T V V N S T F S I V L G N K G Y I C T V T V E C M R N C
1
I G T T V V N S T F S I V L G N K G Y I C T V T V E C M R N C Q
32
50.0%
NZ_BMVL01000013.1 and 1 other:
NZ_BMVL01000013.1 Lanthipeptides: IE257_RS28650_lanthipeptide
Lanthipeptides: IE257_RS28650_lanthipeptide
1
I G T T V V N S T F S I V L G N K G Y I C T V T V E C M R N C S K
33
I T V + S L G N G++C T V T V E C +N C +
2
I F E T V T Y T V A S W A L G N N G H L C T V T V E C Q K N C Q R
34
with 101 more sequence matches
Only the first 10 are displayed here.
48.6%
NZ_QKTG01000020.1 and 1 other:
NZ_QKTG01000020.1 Lanthipeptides: DEI99_RS16920_lanthipeptide
Lanthipeptides: DEI99_RS16920_lanthipeptide
1
I G T T V V N S T---F S I V L G N K G Y I C T V T V E C M R N C
31
I G T T V + S L G N G C T T V E C N C
3
I G T T V T T L S C Y G V S W A L G N D G N F C T A T V E C Q S N C
36
48.5%
NZ_BMMP01000005.1 and 3 others:
NZ_BMMP01000005.1 Lanthipeptides: IEY56_RS28370_lanthipeptide NZ_FMHJ01000003.1 Lanthipeptides: H181DRAFT_RS07545_lanthipeptide NZ_FMHJ01000003.1 Lanthipeptides: H181DRAFT_RS07545_lanthipeptide
Lanthipeptides: IEY56_RS28370_lanthipeptide
8
S T F S I--V L G N K G Y I C T V T V E C M R N C S
32
+T F S+ V L G N G C T+T V E C N C+
4
N T F S L S D V L G N T G G W C T L T V E C Q P N C N
30
45.5%
NZ_CP016795.1 and 5 others:
NZ_CP016795.1 Lanthipeptides: BC342_RS18360_lanthipeptide NZ_CP036534.1 Lanthipeptides: EZV63_RS18960_lanthipeptide NZ_CP036534.1 Lanthipeptides: EZV63_RS18960_lanthipeptide NZ_CP094676.1 Lanthipeptides: L6J92_RS01495_lanthipeptide NZ_CP094676.1 Lanthipeptides: L6J92_RS01495_lanthipeptide
Lanthipeptides: BC342_RS18360_lanthipeptide
8
S T F S I--V L G N K G Y I C T V T V E C M R N C S
32
+T F S+ L G N G C T+T E C N C S
4
N T F S L S D A L G N H G G W C T L T K E C Q P N C S
30
45.5%
NZ_CP047419.1 and 3 others:
NZ_CP047419.1 Lanthipeptides: GTU71_RS12805_lanthipeptide NZ_PSTO01000045.1 Lanthipeptides: C5C10_RS15590_lanthipeptide NZ_PSTO01000045.1 Lanthipeptides: C5C10_RS15590_lanthipeptide
Lanthipeptides: GTU71_RS12805_lanthipeptide
9
T F S I V L G N K G Y I C T V T V E C M R N C
31
T S V L G N+G C T+T V E C N C
7
T L S N V L G N Q G G W C T L T V E C Q P N C
29
45.5%
NZ_KV795763.1 and 2 others:
NZ_KV804818.1 Lanthipeptides: allorf_114850_115005_lanthipeptide NZ_KV804818.1 Lanthipeptides: allorf_114850_115005_lanthipeptide
Lanthipeptides: allorf_248182_248337_lanthipeptide
4
T V V N S T F S I V L G N K G Y I C T V T V E C M R N C S
32
T +S V+G N+G +C T V T V E C M C
1
T A F P G W Y S K V I G N R G R V C T V T V E C M S V C Q
29
44.1%
NZ_BQXZ01000001.1 and 1 other:
NZ_BQXZ01000001.1 Lanthipeptides: OCU69_RS05000_lanthipeptide
Lanthipeptides: OCU69_RS05000_lanthipeptide
9
T F S I V L G N K G Y I C T V T V E C M R N C S K
33
T S+ +G N K G +C T T+E C N C S K
10
T L S V Y M G N K G S V C T W T I E C Q S N C S K
34
42.4%
NC_002570.2 and 3 others:
NC_002570.2 Lanthipeptides: AYT26_RS02480_lanthipeptide NZ_CP040441.1 Lanthipeptides: FED51_RS02600_lanthipeptide NZ_CP040441.1 Lanthipeptides: FED51_RS02600_lanthipeptide
Lanthipeptides: AYT26_RS02480_lanthipeptide
11
S I V L G N K G Y I C T V T V E C M R N C S
32
S L G N K G C T+T V E C M +C+
11
S C R L G N K G A Y C T L T V E C M P S C N
32
42.4%
NC_006322.1 and 7 others:
NC_006322.1 Lanthipeptides: BLI_RS20295_lanthipeptide NZ_CP033218.1 Lanthipeptides: D9Y32_RS07805_lanthipeptide NZ_CP033218.1 Lanthipeptides: D9Y32_RS07805_lanthipeptide NZ_LQYL01000021.1 Lanthipeptides: B4090_RS08835_lanthipeptide NZ_LQYL01000021.1 Lanthipeptides: B4090_RS08835_lanthipeptide NZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11865_lanthipeptide NZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11865_lanthipeptide
Lanthipeptides: BLI_RS20295_lanthipeptide
10
F S I V L G N K G Y I C T V T V E C M R N C S
32
S L G N G Y+C T V T E C M +C+
10
L S K P L G N N G Y L C T V T K E C M P S C N
32
42.4%
NC_018499.1 and 10 others:
NC_018499.1 Lanthipeptides: BCK_RS27855_lanthipeptide NC_018499.1 Lanthipeptides: BCK_RS27850_lanthipeptide NC_018499.1 Lanthipeptides: BCK_RS27860_lanthipeptide NC_018499.1 Lanthipeptides: BCK_RS27855_lanthipeptide NC_018499.1 Lanthipeptides: BCK_RS27850_lanthipeptide NZ_JAOPQW010000026.1 Lanthipeptides: OCD10_RS25275_lanthipeptide NZ_JAOPQW010000026.1 Lanthipeptides: OCD10_RS25270_lanthipeptide NZ_MLKL01000042.1 Lanthipeptides: BKK45_RS27570_lanthipeptide NZ_MLKL01000042.1 Lanthipeptides: BKK45_RS27565_lanthipeptide NZ_MLKL01000042.1 Lanthipeptides: BKK45_RS27560_lanthipeptide
Lanthipeptides: BCK_RS27860_lanthipeptide
5
V V N S T F S I V L G N K G Y I C T V T V E C M R N C S
32
V S L G N K G C T+T E C M +C+
5
V T P E G L S S W L G N K G G Y C T L T K E C M P S C N
32
42.4%
NZ_AKXV01000031.1 and 4 others:
NZ_AKXV01000031.1 Lanthipeptides: Y19_RS0109895_lanthipeptide NZ_JABBGE010000004.1 Lanthipeptides: HHL19_RS13545_lanthipeptide NZ_LMEI01000006.1 Lanthipeptides: ASC82_RS06140_lanthipeptide NZ_LMEI01000006.1 Lanthipeptides: ASC82_RS06140_lanthipeptide
Lanthipeptides: Y19_RS0109895_lanthipeptide
8
S T F S I--V L G N K G Y I C T V T V E C M R N C S
32
+T F S+ L G N+G C T+T E C N C+
4
N T F S L S D F L G N Q G G W C T L T K E C Q P N C N
30

#### MIBiG 4.0 matches for PGX70_RS05515

42.4%
BGC0000517.4 (BAB04173.1):
Lanthipeptide: haloduracin β or haloduracin α
11
S I V L G N K G Y I C T V T V E C M R N C S
32
S L G N K G C T+T V E C M +C+
7
S C R L G N K G A Y C T L T V E C M P S C N
28
42.4%
BGC0002110.3 (QKV49893.1):
Lanthipeptide: birimositide
8
S T F S I--V L G N K G Y I C T V T V E C M R N C S
32
+T F S+ L G N G C T+T E C N C+
4
N T F S L S N A L G N N G G W C T L T K E C Q P N C N
30
15.4%
BGC0001229.4 (SBI_06990):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
21
C T V T V E C M R N C
31
C T++ E C N C
28
C T L S K E C Q P N C
38
PGX70_RS05520
Leader:
MKSNLLKINNVTEMEKNMVTLIKDEDMELAGG
Core:
S T P A C A I G V V G I T V A V T G I S T A C T S R C I N K
Core with dehydrations:
Dha Dhb P A Cys A I G V V G I Dhb V A V Dhb G I Dha Dhb A Cys Dhb Dha R Cys I N K

#### antiSMASH-DB 4.0 matches for PGX70_RS05520

100.0%
NC_018089.1 and 13 others:
NC_018089.1 Lanthipeptides: SMUGS5_RS08730_lanthipeptide NZ_CP043405.1 Lanthipeptides: FY406_RS04350_lanthipeptide NZ_CP043405.1 Lanthipeptides: FY406_RS04350_lanthipeptide NZ_CP044493.1 Lanthipeptides: FSA40_RS09070_lanthipeptide NZ_CP044493.1 Lanthipeptides: FSA40_RS09070_lanthipeptide NZ_CP050270.1 Lanthipeptides: HB753_RS00320_lanthipeptide NZ_CP050270.1 Lanthipeptides: HB753_RS00320_lanthipeptide NZ_JADPAN010000004.1 Lanthipeptides: I4U28_RS03990_lanthipeptide NZ_JADPAN010000004.1 Lanthipeptides: I4U28_RS03990_lanthipeptide NZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS08125_lanthipeptide NZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS08125_lanthipeptide NZ_JAQCYD010000003.1 Lanthipeptides: PGX70_RS05520_lanthipeptide NZ_JAQCYD010000003.1 Lanthipeptides: PGX70_RS05520_lanthipeptide
Lanthipeptides: SMUGS5_RS08730_lanthipeptide
1
S T P A C A I G V V G I T V A V T G I S T A C T S R C I N K
30
S T P A C A I G V V G I T V A V T G I S T A C T S R C I N K
1
S T P A C A I G V V G I T V A V T G I S T A C T S R C I N K
30
43.3%
NZ_CP034414.1 and 1 other:
NZ_CP034414.1 Lanthipeptides: EI692_RS18435_lanthipeptide
Lanthipeptides: EI692_RS18435_lanthipeptide
2
T P A C A I G V V G I T V A V T G I S T A C T S R C
27
T P A +I V G T S T A C T C
2
T P A I S I L V S G F I S T N T C P S T A C T R A C
27
40.6%
NZ_NUML01000015.1:
Lanthipeptides: COD66_RS20140_lanthipeptide
1
S T P A C A I G V V G I T V A V T G I S T A C T S R C
27
+T P A V V G I+V + +T C T S+C
7
T T P A T P T I V V G I S V G L C P-T T K C T S K C
32
with 19 more sequence matches
Only the first 10 are displayed here.
40.0%
NZ_JAMXMK010000009.1:
Lanthipeptides: NGM22_RS28125_lanthipeptide
1
S T P A C A I G V V G I T V A V T G I S T A C T S R C
27
S T P A C A V G+T+A G C
7
S T P A C A---V G V T I A A W G A H K L S Y W N C
30
39.4%
NC_015215.1 and 5 others:
NC_015215.1 Lanthipeptides: SGGBAA2069_RS00700_lanthipeptide NZ_JAKUYO010000004.1 Lanthipeptides: MK556_RS09790_lanthipeptide NZ_JAKUYO010000004.1 Lanthipeptides: MK556_RS09790_lanthipeptide NZ_JAMDHZ010000003.1 Lanthipeptides: M5Q10_RS05355_lanthipeptide NZ_JAMDHZ010000003.1 Lanthipeptides: M5Q10_RS05355_lanthipeptide
Lanthipeptides: SGGBAA2069_RS00700_lanthipeptide
1
S T P A C A---I G V V G I T V A V T G I S T A C T S R C I N
29
S T P C A + + A+ I+T A C T+R C +
1
S T P G C A W A A V S A I S T V S A L F Q I T T A C T T R C Y H
32
37.5%
NZ_CP036019.1 and 1 other:
NZ_CP036019.1 Lanthipeptides: EXW52_RS27205_lanthipeptide
Lanthipeptides: EXW52_RS27205_lanthipeptide
1
S T P A C A I G V V G I T V A V T G I S T A C T S R C
27
+T P A V V I+V + +T C T S+C
7
T T P A T P T I V V A I S V G L C P-T T K C T S K C
32
31.4%
NZ_CM000721.1 and 9 others:
NZ_CP015591.1 Lanthipeptides: A7A70_RS27555_lanthipeptide NZ_CP078085.1 Lanthipeptides: KU891_RS29360_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptide NZ_NUBO01000052.1 Lanthipeptides: CN575_RS29785_lanthipeptide NZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptide NZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptide
Lanthipeptides: BCERE0010_RS29355_lanthipeptide
9
V V G I T V A V T G---I S T A C T S R C
27
++G T+A V T +T C T S R C
14
I I G A T I A V T A S L C P T T K C T S R C
35
31.0%
NZ_NTSR01000029.1 and 1 other:
NZ_NTSR01000029.1 Lanthipeptides: CN358_RS25165_lanthipeptide
Lanthipeptides: CN358_RS25165_lanthipeptide
5
C A I G--V V G I T V A V T G I S------T A C T S R C
27
C A+G V G I T+ S +A C+S R C
11
C A V G G A T V G I T I Y T F D R S H Q S C P T S A C S S R C
41
30.0%
NZ_CP084530.1 and 1 other:
NZ_CP084530.1 Lanthipeptides: LDO05_RS02090_lanthipeptide
Lanthipeptides: LDO05_RS02090_lanthipeptide
9
V V G I T V A V T G I S T A C T S R C
27
+ G+ A S T A C T S+C
10
I C G V A S A A F C P S T A C T S K C
28
26.7%
NC_014622.2 and 5 others:
NC_017542.1 Lanthipeptides: PPM_RS22280_lanthipeptide NZ_CP029370.1 Lanthipeptides: DI243_RS20990_lanthipeptide NZ_CP034141.1 Lanthipeptides: EGM68_RS21685_lanthipeptide NZ_PNXP01000027.1 Lanthipeptides: C1I59_RS20700_lanthipeptide NZ_POVS01000032.1 Lanthipeptides: C1T21_RS26405_lanthipeptide
Lanthipeptides: PPSC2_RS50140_lanthipeptide
1
S T P A C A I G V V G I T V A V
16
S T P + V+G+T V V
7
S T P T I T V T V I G V T V L V
22
26.7%
NZ_CM000752.1 and 15 others:
NZ_CM000752.1 Sactipeptides: BTHUR0007_RS37430_sactipeptide NZ_JABGBR020000007.1 Sactipeptides: HOV72_RS15955_sactipeptide NZ_JABGBR020000007.1 Sactipeptides: HOV72_RS15950_sactipeptide NZ_JYPH01000039.1 Sactipeptides: TU52_RS33370_sactipeptide NZ_JYPH01000039.1 Sactipeptides: TU52_RS33365_sactipeptide NZ_NJPZ01000025.1 Sactipeptides: CE087_RS29070_sactipeptide NZ_NJPZ01000025.1 Sactipeptides: CE087_RS29065_sactipeptide NZ_NJPZ01000025.1 Sactipeptides: CE087_RS29060_sactipeptide NZ_NUBO01000020.1 Sactipeptides: CN575_RS31360_sactipeptide NZ_NUBO01000020.1 Sactipeptides: CN575_RS31355_sactipeptide NZ_NUBO01000020.1 Sactipeptides: CN575_RS31350_sactipeptide NZ_NUUQ01000016.1 Sactipeptides: COI65_RS30820_sactipeptide NZ_NUUQ01000016.1 Sactipeptides: COI65_RS30815_sactipeptide NZ_NUUQ01000016.1 Sactipeptides: COI65_RS30810_sactipeptide NZ_NUXK01000018.1 Sactipeptides: COJ27_RS31850_sactipeptide
Sactipeptides: BTHUR0007_RS37435_sactipeptide
4
A C A I G V V G I T V A V T G I S T A
22
A C++ ++ + A T G S T A
11
A C S V E L L N L V T A A T G A S T A
29
26.7%
NZ_JAQQWR010000009.1:
Lanthipeptides: PQ473_RS20135_lanthipeptide
1
S T P A C A I G V V G I T V A V T G I S
20
+T P A C G + I T+ V ++
7
T T P A C I Y G G I A I T I G V V S V A
26
25.6%
NZ_CP009280.1 and 1 other:
NZ_CP009280.1 Lanthipeptides: P40081_RS37160_lanthipeptide
Lanthipeptides: P40081_RS37160_lanthipeptide
5
C A I G V V G I T V A V T G I S T A C T S R C
27
C I G V I+ + +T C T S+C
18
C V I G A V D I S A N L C P-T T K C T S K C
39

#### MIBiG 4.0 matches for PGX70_RS05520

16.7%
BGC0002110.3 (QKV49894.1):
Lanthipeptide: birimositide
20
S T A C T S R C
27
+T C T S+C
19
T T K C T S K C
26
16.2%
BGC0001229.4 (SBI_06989):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
20
S T A C T S R C
27
+T C T S R C
30
T T K C T S R C
37

#### Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine
Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
CcpA
Description: Catabolite control protein A
Species: Streptococcus & Clostridium sp.
Score: 18.02 out of 20.97
Confidence: medium
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.93 out of 26.06
Confidence: medium
GnfM
Description: Regulator of nitrogen-fixation genes
Species: Geobacter sulfurreducens PCA
Score: 21.52 out of 27.55
Confidence: medium
Additional weak hits (1):
FuR variant 2
Description: Ferric Uptake Regulator
Species: Caulobacter crescentus CB15
Score: 22.83 out of 32.74
Confidence: weak
Lanthipeptides
TFBS Finder
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.

PGX70_RS05515 - Class II
  Cleavage pHMM score: -3.00
  RODEO score: 0
  Monoisotopic mass: 3392.7 Da
  Molecular weight: 3395.0 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3413.0 Da N = 1
    3431.0 Da N = 2
    3449.0 Da N = 3
    3467.0 Da N = 4
    3485.1 Da N = 5
PGX70_RS05520 - Class II
  Cleavage pHMM score: 2.60
  RODEO score: 0
  Monoisotopic mass: 2748.5 Da
  Molecular weight: 2750.2 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2768.3 Da N = 1
    2786.3 Da N = 2
    2804.3 Da N = 3
    2822.3 Da N = 4
    2840.3 Da N = 5
PGX70_RS05515 - Class II
  Cleavage pHMM score: -3.00
  RODEO score: 0
  Monoisotopic mass: 3392.7 Da
  Molecular weight: 3395.0 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3413.0 Da N = 1
    3431.0 Da N = 2
    3449.0 Da N = 3
    3467.0 Da N = 4
    3485.1 Da N = 5
PGX70_RS05520 - Class II
  Cleavage pHMM score: 2.60
  RODEO score: 0
  Monoisotopic mass: 2748.5 Da
  Molecular weight: 2750.2 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2768.3 Da N = 1
    2786.3 Da N = 2
    2804.3 Da N = 3
    2822.3 Da N = 4
    2840.3 Da N = 5

TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
CcpA | Catabolite control protein A
GnfM | Regulator of nitrogen-fixation genes
MogR | Repressor of flagellar motility genes

NZ_JAQCYD010000005.1 - Region 1 - RRE-containing,RaS-RiPP
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1 - 12,887 nt. (total: 12,887 nt) Show pHMM detection rules used
Region on contig edge.
RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])
RaS-RiPP: (PF04055 and TIGR01716)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
No tailoring functions detected.
Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RRE-containing | RaS-RiPP | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | --- | ---
BGC0002583.2 |  |  | 1.54 | ribosomal | tryglysin B | Streptococcus mutans UA159
BGC0001929.2 |  |  | 0.96 | ribosomal | WGK | Streptococcus ferus
BGC0001209.3 |  |  | 0.47 | ribosomal | streptide | Streptococcus thermophilus LMD-9
BGC0001025.5 |  |  | 0.10 | NRPS, PKS | myxovirescin A1 | Myxococcus xanthus DK 1622

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002583.2 |  | 0.92 | ribosomal | tryglysin B | Streptococcus mutans UA159
BGC0001929.2 |  | 0.77 | ribosomal | WGK | Streptococcus ferus
BGC0001209.3 |  | 0.57 | ribosomal | streptide | Streptococcus thermophilus LMD-9
BGC0001025.5 |  | 0.22 | NRPS, PKS | myxovirescin A1 | Myxococcus xanthus DK 1622

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.
Location:
Identifier
Identity
Coverage
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
RpoN
Description: Regulator of nitrogen assimilation and virulence
Species: Salmonella & Vibrio sp.
Score: 17.31 out of 18.46
Confidence: strong
PerR
Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 26.23 out of 28.14
Confidence: medium
ZuR variant 1
Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 23.01 out of 28.19
Confidence: medium
Additional weak hits (3):
RutR
Description: Regulator of the pyrimidine and purine metabolism
Species: Escherichia coli str. K-12 substr. MG1655
Score: 20.06 out of 26.85
Confidence: weak
HypR
Description: L-hydroxyproline utilization repressor
Species: Streptomyces coelicolor
Score: 18.94 out of 22.40
Confidence: weak
RutR
Description: Regulator of the pyrimidine and purine metabolism
Species: Escherichia coli str. K-12 substr. MG1655
Score: 20.01 out of 26.85
Confidence: weak
RREFinder
TFBS Finder
RRE predictions
RREfinder results sidepanel.

RRE-containing protocluster (0...12887)
PGX70_RS06990
  RRE type: Streptide_RRE
  Location: 5 - 105
  Score: 129.5
  RRE type: Stand_Alone_Lasso_RRE
  Location: 5 - 79
  Score: 34.2
RaS-RiPP protocluster (0...12567)
PGX70_RS06990
  RRE type: Streptide_RRE
  Location: 5 - 105
  Score: 129.5
  RRE type: Stand_Alone_Lasso_RRE
  Location: 5 - 79
  Score: 34.2

TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
PerR | Peroxide regulator
RpoN | Regulator of nitrogen assimilation and virulence
ZuR variant 1 | Zinc-responsive repressor

NZ_JAQCYD010000007.1 - Region 1 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 40,433 - 50,838 nt. (total: 10,406 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: dehydrogenase
PGX70_RS08850: aldehyde dehydrogenase

smcogs
  SMCOG1017: aldehyde dehydrogenase

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000897.5 |  | 0.29 | other (other) | dehydrophos | Streptomyces luridus
BGC0000938.5 |  | 0.27 | other (aminocoumarin) | fosfomycin | Streptomyces fradiae
BGC0000807.3 |  | 0.26 | saccharide | phosphonoglycans | Stackebrandtia nassauensis DSM 44728
BGC0001055.5 |  | 0.23 | NRPS, PKS | yersiniabactin | Escherichia coli
BGC0000806.5 |  | 0.22 | saccharide | phosphonoglycans | Glycomyces sp. NRRL B-16210
BGC0000654.4 |  | 0.20 | saccharide, terpene | phenalinolactone A | Streptomyces sp. Tu6071

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000897.5 |  | 0.29 | other (other) | dehydrophos | Streptomyces luridus
BGC0000938.5 |  | 0.27 | other (aminocoumarin) | fosfomycin | Streptomyces fradiae
BGC0000807.3 |  | 0.26 | saccharide | phosphonoglycans | Stackebrandtia nassauensis DSM 44728
BGC0001055.5 |  | 0.23 | NRPS, PKS | yersiniabactin | Escherichia coli
BGC0000806.5 |  | 0.22 | saccharide | phosphonoglycans | Glycomyces sp. NRRL B-16210
BGC0000654.4 |  | 0.20 | saccharide, terpene | phenalinolactone A | Streptomyces sp. Tu6071

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
CRP
Description: Cyclic AMP receptor protein
Species: Escherichia coli str. K-12 substr. MG1655
Score: 18.06 out of 19.26
Confidence: strong
CRP
Description: Cyclic AMP receptor protein
Species: Escherichia coli str. K-12 substr. MG1655
Score: 17.40 out of 19.26
Confidence: medium
PsrA
Description: Oleic acid responsive regulator
Species: Pseudomonas sp.
Score: 21.18 out of 25.88
Confidence: medium
ZuR variant 1
Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 22.18 out of 28.19
Confidence: medium
Additional weak hits (4):
PerR
Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 22.61 out of 28.14
Confidence: weak
MntR
Description: Manganese transport regulator
Species: Escherichia coli str. K-12 substr. MG1655
Score: 26.20 out of 39.62
Confidence: weak
CelR
Description: Cellobiose uptake repressor
Species: Streptomyces coelicolor
Score: 20.05 out of 30.11
Confidence: weak
CelR
Description: Cellobiose uptake repressor
Species: Streptomyces coelicolor
Score: 20.05 out of 30.11
Confidence: weak
TFBS Finder
TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
CRP | Cyclic AMP receptor protein
PsrA | Oleic acid responsive regulator
ZuR variant 1 | Zinc-responsive repressor

NZ_JAQCYD010000008.1 - Region 1 - NRPS,NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1 - 51,564 nt. (total: 51,564 nt) Show pHMM detection rules used
Region on contig edge.
NRPS: cds(Condensation and (AMP-binding or A-OX) and not alpha_am_amid)
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX) and not alpha_am_amid)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
TFBS Finder
NRPS/PKS modules
NRPS/PKS domains
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: dehydrogenase
PGX70_RS09205: short-chain dehydrogenase/reductase SDR

smcogs
  SMCOG1001: short-chain dehydrogenase/reductase SDR

Transferases: PPTase acylase
PGX70_RS09110: malonyl CoA-acyl carrier protein transacylase

smcogs
  SMCOG1021: malonyl CoA-acyl carrier protein transacylase

PGX70_RS09150: malonyl CoA-acyl carrier protein transacylase

smcogs
  SMCOG1021: malonyl CoA-acyl carrier protein transacylase

PGX70_RS09160: 4'-phosphopantetheinyl transferase

smcogs
  SMCOG1012: 4'-phosphopantetheinyl transferase

Hydrolases: esterase hydrolase
PGX70_RS09100: thioesterase

smcogs
  SMCOG1004: thioesterase

PGX70_RS09200: metallo-beta-lactamase family protein

smcogs
  SMCOG1170: metallo-beta-lactamase family protein

PGX70_RS09215: putative esterase

smcogs
  SMCOG1104: putative esterase

Ligases: ligase synthase
PGX70_RS09105: AMP-dependent synthetase and ligase

smcogs
  SMCOG1002: AMP-dependent synthetase and ligase

PGX70_RS09115: Beta-ketoacyl synthase

smcogs
  SMCOG1022: Beta-ketoacyl synthase

PGX70_RS09120: AMP-dependent synthetase and ligase

smcogs
  SMCOG1002: AMP-dependent synthetase and ligase

PGX70_RS09125: AMP-dependent synthetase and ligase

smcogs
  SMCOG1002: AMP-dependent synthetase and ligase

PGX70_RS09130: condensation domain-containing protein

smcogs
  SMCOG1127: condensation domain-containing protein

PGX70_RS09135: condensation domain-containing protein

smcogs
  SMCOG1127: condensation domain-containing protein

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS | NRPS-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | --- | ---
BGC0001825.4 |  |  | 0.74 | NRPS | xenematide | Xenorhabdus nematophila AN6/1
BGC0002135.2 |  |  | 0.70 | NRPS | bovienimide A | Xenorhabdus bovienii SS-2004
BGC0000342.4 |  |  | 0.69 | NRPS | enniatin | Fusarium equiseti
BGC0001833.4 |  |  | 0.69 | NRPS | icosalide A, icosalide B | Burkholderia gladioli
BGC0001132.4 |  |  | 0.68 | NRPS | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0001133.4 |  |  | 0.68 | NRPS | taxlllaid A | Xenorhabdus bovienii SS-2004
BGC0001166.5 |  |  | 0.67 | NRPS | HC-toxin | Alternaria jesenskae
BGC0002286.3 |  |  | 0.66 | NRPS | ririwpeptide A, ririwpeptide B, ririwpeptide C | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001128.4 |  |  | 0.66 | NRPS | gamexpeptide C | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001135.5 |  |  | 0.65 | NRPS | bicornutin A1, bicornutin A2 | Xenorhabdus budapestensis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001825.4 |  | 0.71 | NRPS | xenematide | Xenorhabdus nematophila AN6/1
BGC0002135.2 |  | 0.70 | NRPS | bovienimide A | Xenorhabdus bovienii SS-2004
BGC0001833.4 |  | 0.69 | NRPS | icosalide A, icosalide B | Burkholderia gladioli
BGC0001132.4 |  | 0.69 | NRPS | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0001166.5 |  | 0.68 | NRPS | HC-toxin | Alternaria jesenskae
BGC0001251.4 |  | 0.68 | NRPS | epichloenin A | Epichloe festucae
BGC0001250.4 |  | 0.68 | NRPS | epichloenin A | Epichloe festucae
BGC0001133.4 |  | 0.68 | NRPS | taxlllaid A | Xenorhabdus bovienii SS-2004
BGC0001128.4 |  | 0.68 | NRPS | gamexpeptide C | Photorhabdus laumondii subsp. laumondii TTO1
BGC0002286.3 |  | 0.68 | NRPS | ririwpeptide A, ririwpeptide B, ririwpeptide C | Photorhabdus laumondii subsp. laumondii TTO1

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 24.27 out of 26.06
Confidence: strong
PerR
Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 24.88 out of 28.14
Confidence: medium
IolR
Description: Regulator of the inositol catabolism
Species: Caulobacter crescentus CB15
Score: 19.11 out of 23.79
Confidence: medium
CatR
Description: H2O2-responsive repressor
Species: Streptomyces coelicolor
Score: 20.67 out of 25.31
Confidence: medium
DasR
Description: N-acetylglucosamine dependent repressor
Species: Streptomyces coelicolor
Score: 21.39 out of 27.04
Confidence: medium
GnfM
Description: Regulator of nitrogen-fixation genes
Species: Geobacter sulfurreducens PCA
Score: 21.51 out of 27.55
Confidence: medium
Additional weak hits (3):
ClgR
Description: Caseinolytic protease gene regulator
Species: Corynebacterium glutamicum ATCC 13032
Score: 19.74 out of 30.22
Confidence: weak
CsoR
Description: Copper-responsive repressor
Species: Streptomyces lividans
Score: 19.96 out of 32.38
Confidence: weak
DosR
Description: Hypoxia stress response regulator
Species: Mycobacterium tuberculosis H37Rv
Score: 19.68 out of 29.51
Confidence: weak
Module view
Shows module structures for each candidate cluster in NRPS and PKS regions.
Genes are shown in predicted order, and are only present when containing at least one complete module.
A domain glossary is available here, and an explanation of the visualisation is available here.
Legend
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
NRPS/PKS products
NRPS/PKS substrates
TFBS Finder
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 0 - 51564:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (fatty_acid) + (mal - Leu) + (D-Ser - Pro) + (Val) + (Cys) + (Gly)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 0 - 25694:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (fatty_acid) + (mal - Leu) + (D-Ser - Pro) + (Val) + (Cys)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS substrate predictions
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
PGX70_RS09105: fatty_acid
CAL_domain (150..448): fatty_acid
minowa: fatty_acid

Prediction, score:
  fatty_acid: 52.0
  NH2: 11.6
  shikimic_acid: 0.0
  Acetyl-CoA: 0.0
  AHBA: 0.0

PGX70_RS09110: pk
PKS_AT (29..290): pk
ATSignature: Malonyl-CoA

Top 3 matches:
  Malonyl-CoA: 58.3%

minowa: Methoxymalonyl-CoA

Prediction, score:
  Methoxymalonyl-CoA: 24.5
  Malonyl-CoA: 18.8
  inactive: 16.4
  Methylmalonyl-CoA: 10.0
  trans-1,2-CPDA: 0.0
  fatty_acid: 0.0
  Propionyl-CoA: 0.0
  Isobutyryl-CoA: 0.0
  Ethylmalonyl-CoA: 0.0
  CHC-CoA: 0.0
  Benzoyl-CoA: 0.0
  Acetyl-CoA: 0.0
  3-Methylbutyryl-CoA: 0.0
  2-Methylbutyryl-CoA: 0.0

PGX70_RS09120: Leu - Ser
Search NORINE for peptide: strict or relaxed
AMP-binding (203..587): Leu
nrpys: Leu

SVM prediction details:
  Predicted physicochemical class:
    hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
  Large clusters prediction:
    Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
  Small clusters prediction:
    Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
  Single AA prediction:
    leu (Leu)

Stachelhaus prediction details:
  Stachelhaus sequence:
    LWHAFDASIWEPFLLTGAEYNNYGPTEYTVVATS
  Nearest Stachelhaus code(s):
    Leu DAWFLGNVVK (88% 8Å match)
  Stachelhaus code match:
    100% (strong)

AMP-binding (1229..1628): Ser
nrpys: Ser

SVM prediction details:
  Predicted physicochemical class:
    hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
  Large clusters prediction:
    Aliphatic chain or phenyl group with -OH (Ser, Thr, Dhpg, Hpg)
  Small clusters prediction:
    ser (Ser)
  Single AA prediction:
    ser (Ser)

Stachelhaus prediction details:
  Stachelhaus sequence:
    RWMTFDVSIWEGHFFSSGEINLYGPTETAIEVTY
  Nearest Stachelhaus code(s):
    Ser DVWHFSLIEK (88% 8Å match)
  Stachelhaus code match:
    100% (strong)

PGX70_RS09125: Pro
Search NORINE for peptide: strict or relaxed
AMP-binding (241..630): Pro
nrpys: Pro

SVM prediction details:
  Predicted physicochemical class:
    hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
  Large clusters prediction:
    Cyclic aliphatic chain (polar NH2 group) (Pro, Hpr)
  Small clusters prediction:
    pro (Pro)
  Single AA prediction:
    pro (Pro)

Stachelhaus prediction details:
  Stachelhaus sequence:
    LFQAFDVASQESFLIVAGEYNHYGPSETHVVSID
  Nearest Stachelhaus code(s):
    Pro DVQFIAHVVK (79% 8Å match)
  Stachelhaus code match:
    100% (strong)

PGX70_RS09130: Val - Cys
Search NORINE for peptide: strict or relaxed
AMP-binding (23..417): Val
nrpys: Val

SVM prediction details:
  Predicted physicochemical class:
    hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
  Large clusters prediction:
    Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
  Small clusters prediction:
    Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
  Single AA prediction:
    val (Val)

Stachelhaus prediction details:
  Stachelhaus sequence:
    LDNSFDASTLEAFFIIGGDYNGYGPTENTVFTTM
  Nearest Stachelhaus code(s):
    Val DALFIGGTFK (71% 8Å match)
    Leu or Ile DALFIGGTFK (65% 8Å match)
  Stachelhaus code match:
    90% (moderate)

AMP-binding (1059..1448): Cys
nrpys: Cys

SVM prediction details:
  Predicted physicochemical class:
    hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
  Large clusters prediction:
    Polar, uncharged (aliphatic with -SH) (Cys)
  Small clusters prediction:
    Polar, uncharged (aliphatic with -SH) (Cys)
  Single AA prediction:
    Polar, uncharged (aliphatic with -SH) (Cys)

Stachelhaus prediction details:
  Stachelhaus sequence:
    TDISFDLSVYDGNSILSGDFSAGGATEGSIWSIY
  Nearest Stachelhaus code(s):
    Cys DLYNLSAIWK (82% 8Å match)
  Stachelhaus code match:
    90% (moderate)

PGX70_RS09135: Gly
Search NORINE for peptide: strict or relaxed
AMP-binding (527..891): Gly
nrpys: Gly

SVM prediction details:
  Predicted physicochemical class:
    hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
  Large clusters prediction:
    Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
  Small clusters prediction:
    Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
  Single AA prediction:
    gly (Gly)

Stachelhaus prediction details:
  Stachelhaus sequence:
    FAITFDIFILEFQSLVGGEINLYGPTEATVWAFA
  Nearest Stachelhaus code(s):
    Gly DILQLGLVWK (76% 8Å match)
  Stachelhaus code match:
    100% (strong)

PGX70_RS09150: pk
PKS_AT (7..290): pk
ATSignature: (unknown)
No matches above 50%
minowa: trans-1,2-CPDA

Prediction, score:
  trans-1,2-CPDA: 0.0
  inactive: 0.0
  fatty_acid: 0.0
  Propionyl-CoA: 0.0
  Methylmalonyl-CoA: 0.0
  Methoxymalonyl-CoA: 0.0
  Malonyl-CoA: 0.0
  Isobutyryl-CoA: 0.0
  Ethylmalonyl-CoA: 0.0
  CHC-CoA: 0.0
  Benzoyl-CoA: 0.0
  Acetyl-CoA: 0.0
  3-Methylbutyryl-CoA: 0.0
  2-Methylbutyryl-CoA: 0.0

Link to PARAS substrate predictor
TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
CatR | H2O2-responsive repressor
DasR | N-acetylglucosamine dependent repressor
GnfM | Regulator of nitrogen-fixation genes
IolR | Regulator of the inositol catabolism
MogR | Repressor of flagellar motility genes
PerR | Peroxide regulator