LOCUS       NZ_JAQEMJ010000010     22616 bp    DNA     linear   CON 22-FEB-2024
DEFINITION  Bacillus velezensis strain TM115-48 GF3HH28002B.Scaf10, whole genome
            shotgun sequence.
ACCESSION   NZ_JAQEMJ010000010
VERSION     NZ_JAQEMJ010000010.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus velezensis
  ORGANISM  Bacillus velezensis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus amyloliquefaciens group.
REFERENCE   1  (bases 1 to 179705)
  AUTHORS   Lin,X., Hu,T., Chen,J., Liang,H., Zhou,J., Wu,Z., Ye,C., Jin,X.,
            Xu,X., Zhang,W., Jing,X., Yang,T., Wang,J., Yang,H., Kristiansen,K.,
            Xiao,L. and Zou,Y.
  TITLE     The genomic landscape of reference genomes of cultivated human gut
            bacteria
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 179705)
  AUTHORS   Zou,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-NOV-2022) BGI Reaserch, BGI-Shenzhen, Beishan
            Industrial Zone, Shenzhen 518083, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. v2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100x
            Sequencing Technology             :: MGI
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/22/2024 04:06:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,454
            CDSs (total)                      :: 4,396
            Genes (coding)                    :: 4,263
            CDSs (with protein)               :: 4,263
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 49
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 69 of 133
            Pseudo Genes (incomplete)         :: 78 of 133
            Pseudo Genes (internal stop)      :: 16 of 133
            Pseudo Genes (multiple problems)  :: 26 of 133
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:15:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 135917
            Orig. end                         :: 158533
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAQEMJ010000010.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22616
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="3"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22616
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22616
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12616](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12616)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            complement(426..1361)
                     /locus_tag="PGW53_RS13045"
     CDS             complement(426..1361)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015416707.1"
                     /locus_tag="PGW53_RS13045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_270354437.1"
                     /transl_table=11
                     /translation="MLELTDLTKKYGDFTAVNHISLCVEKGEIFGLLGPNGAGKSTTVS
                     MISTVLPPTGGTICIDGTSLQEQPAAIKKVMGVVPQEIALYQALSAKDNLAFFGSLYGL
                     SGRELCKRVDEVLDIIELQEQRNQRISEFSGGMKRRVNIGAALMNEPKLFILDEPTVGI
                     DPQSRHHILETVKTLNQEKGMTVIYTSHYMEEVEYLCEKAAIMDHGSIIACGTKDELKQ
                     SAKASDTLIVNAEGLNDDAVKKIRCIPGVAEAAVSQQTITMLVSAADRNILDIADDIRK
                     TGITIKGIHFEEANLESIFLRLTGKTLRDS"
     gene            complement(1503..2147)
                     /locus_tag="PGW53_RS13050"
     CDS             complement(1503..2147)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007408983.1"
                     /locus_tag="PGW53_RS13050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_263612246.1"
                     /transl_table=11
                     /translation="MNVMIADDQSIVREGLKMILSLHEGIQISGEASCGEEVLRILSQS
                     ETDVILMDIRMPGMDGIETTKAVKARYPSVKVIILTTFEDDHYIFAGLKSGADGYLLKD
                     ADSDEIIASLQAVYEGKMMLNPKITVSVVKALNNMEIPAVQEEPQSKLTEILTPRELDV
                     AKHIMEGKSNKRIAADLFLTEGTVKNYVSRILDKLEVSNRTELTLYLQKLL"
     gene            complement(2152..3282)
                     /locus_tag="PGW53_RS13055"
     CDS             complement(2152..3282)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007408982.1"
                     /locus_tag="PGW53_RS13055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sensor histidine kinase"
                     /protein_id="WP_263612247.1"
                     /transl_table=11
                     /translation="MKIAHTKLLIRGFALLSIFHAILQLPPGRGELKVFLSVLVMMLTA
                     NDCLRPLYMKRRPAVYQGSFLLSNVIAGVLLYNVYSVGTQAVMVLLLAEVLITDQQIPA
                     VLLTVNAAAFAAALYAGGAGVSDIVPPYFIMFAVIYLYRKNLQEKSKVELLNRELKTAN
                     DTLKEYSDRIEELAVTKERTRIAQELHDSLGHYLAALKMNLEFAGKTAGHQPDKVKQII
                     HKAHDLTKESILKLRQAVTLLQGSLAGRAFEQELRDIFSHFQEVGGIRFELEMDAAIEA
                     EQPDVKHCLYQSVQETITNAIKHGHASYVSVRIQKNRNMILAHIHNNGSACGTIIKSNG
                     LKGIEKRAAALGGEAVFSSGKETGFDVKIRIPCKEE"
     gene            complement(3293..4006)
                     /locus_tag="PGW53_RS13060"
     CDS             complement(3293..4006)
                     /GO_function="GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017419304.1"
                     /locus_tag="PGW53_RS13060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YjjG family noncanonical pyrimidine nucleotidase"
                     /protein_id="WP_104843043.1"
                     /sec_met_domain="HAD_2 (E-value: 2.8e-21, bitscore: 69.7,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSHYRTLLFDIDNTLLDFTASETDALQKLFQGSKLELTAEVEARY
                     KALNQGLWKAFEEGEMTRDEVVNTRFALLFKEYGLEADGVLMNQAYRQYLEEGHQMIDG
                     AYELIERLSHLFDLYIVTNGVSRSQYKRLGDSGLYPFFKDVFVSEDTGFQKPMKEYFDY
                     VFARIPGFSAEGGLIIGDSLSADIKGGQMAGIDTCWFNPGKKANESGIIPTHEIHSLDE
                     LYDVLNVERKAAAHL"
     gene            complement(4099..5484)
                     /locus_tag="PGW53_RS13065"
     CDS             complement(4099..5484)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007609103.1"
                     /locus_tag="PGW53_RS13065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amino acid permease"
                     /protein_id="WP_270354440.1"
                     /transl_table=11
                     /translation="MANKELKRGLGARHIQMIALGGTIGVGLFMGSSSTIGWTGPSVLL
                     AYAISGIFIFFIMRAMGEMLYVEPSTGSFATFGHKYIHPLAGYMTAWSNWFQWVIVGMS
                     EIIAVGSYMKYWFPDLPAWIPGIIAMAILGAANLISVKSFGEFEFWFAMIKIVTIILMI
                     VAGIGIIFFGFGNGGHAIGLSNLWSHGGFFTNGFSGFFFALSLVVAAYQGVELIGITAG
                     EAKDPQKTLRSAIQSIIWRILIFYIGAIFVIVTVYPWNELHSLGSPFVSTFAKVGITAA
                     AGLINFVVITAAMSGCNSGIFSAGRMLYTLGVNGQAPKFFKKVSSSGVPIFGTLAVLIG
                     LVIGVVLNYIAPPKIFVYVYSASVLPGMIPWFVILISHLGFRRAKGAELDQHPFKMPFA
                     PFTNYLTIAFLLMVLIGMWFNKDTRISLVVGVIFLAIVTVSYYAFGIGKRMPGEKSKIE
                     DAV"
     gene            complement(5910..6341)
                     /locus_tag="PGW53_RS13070"
     CDS             complement(5910..6341)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391881.1"
                     /locus_tag="PGW53_RS13070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_003156749.1"
                     /transl_table=11
                     /translation="MSKQDPIELIEYELTTFIRRAVYLDNSDRKIGHLERAAYLLLRQL
                     DEFGPARVKELAESFKLDISTLSRQAAALESKELIQRFSDPSDGRVSLFAITKLGKQRL
                     KADKKMRLERYHRMLDDWSGDEKEMFGRLLLRLNEAFID"
     gene            6536..6940
                     /locus_tag="PGW53_RS13075"
     CDS             6536..6940
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009968420.1"
                     /locus_tag="PGW53_RS13075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CidA/LrgA family holin-like protein"
                     /protein_id="WP_003156751.1"
                     /transl_table=11
                     /translation="MKVIRIILQIIILFAFSFIGGAVQQFFHLPIPGSIIGLILLIICL
                     SVKIIPVKMIEDGAGFLLSFLPLLFIPAMTGVINYPSLFSASGAALFLIIVLSTIVTMI
                     AAGYASQLLEHKANQRKEKKKCSKHVSQSL"
     gene            6910..7602
                     /locus_tag="PGW53_RS13080"
     CDS             6910..7602
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391882.3"
                     /locus_tag="PGW53_RS13080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LrgB family protein"
                     /protein_id="WP_224223983.1"
                     /transl_table=11
                     /translation="MQQACIAILIILFTAAAYLAMVKLYVRFPYPFLIPVLTTTIFIIA
                     VLLVFHISYKDYMIGGQWINSLLGPAVVALAYPLYKQRRVLIKYMFPIIGGVLAGLFSG
                     MISGLLFAELFGISRSLILSIIPKSITTPVAIQIASGIGGVPSMTVVFVMIAGFSGVIL
                     GPLLLKWIRIRSSLGKGIAFGSASHALGTSKAMEYGELTVSMSSVSMTLCAVLGSVFGP
                     VVAWMFQI"
     gene            7713..8558
                     /locus_tag="PGW53_RS13085"
     CDS             7713..8558
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007609098.1"
                     /locus_tag="PGW53_RS13085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aldo/keto reductase"
                     /protein_id="WP_219194680.1"
                     /transl_table=11
                     /translation="MMTGTIPQKKLLDGTSIPAIGFGTYALNGNNGVHAINSAIDIGYR
                     LIDTAYNYENEGTVGEAIRRSSVPREQLYVTSKLPGRYHDYDKAVQTIQESLYRAGLDY
                     YDLYLVHWPNPKQDRYTEAWQALIDAKKWGLIRSIGVCNFLPEHIERLERETGVKPGIN
                     QIELHPAFNQQQQRQWHEEQGIVTESWSPLSRAGEVLNDQKLGQIADKYDKTISQVILR
                     WHIQLGAIPIPKSASPERQLENISVFDFSLDENDMSIIDSLTRPDGRINGQDPAEYEEF
                     "
     gene            complement(8797..9639)
                     /locus_tag="PGW53_RS13090"
     CDS             complement(8797..9639)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024880.4"
                     /locus_tag="PGW53_RS13090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_270354443.1"
                     /transl_table=11
                     /translation="MTTIKKLLELAKNPEPFEEGTQEVWLDPDRAELVLKSHFDENIPG
                     GSKGSSFVDETVDFITKIAPVECNNKIIDLGCGPGLYSQNLALKGYNVTGVDYNKKSID
                     YAISEADKMNLQIDYKIEDITNLEIESEFDVALLIYQIYGVFSPTNRRKILNNIYRGLK
                     PGGLVLLDVLSEKSYEKFEENLMWFLSKKDSLISDKEHLTLYAAIKYPDNVTLAKNVLI
                     FDDGKLVNYNYWNQHFSIENLEKEVNEAGFNLEKVYADVNGEEYKNNGEFFAAVLKKK"
     misc_feature    9595..9610
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.61"
                     /tool="antismash"
     gene            complement(9801..9938)
                     /locus_tag="PGW53_RS13095"
     CDS             complement(9801..9938)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018887349.1"
                     /locus_tag="PGW53_RS13095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class III lanthipeptide"
                     /protein_id="WP_020955245.1"
                     /transl_table=11
                     /translation="MNDVLELQKLEKETDGKGIAVDATITTTWTVTTTSGFVSSVSNHC
                     "
     CDS_motif       complement(9876..9938)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNDVLELQKLEKETDGKGIAV"
                     /locus_tag="PGW53_RS13095_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9801..9875)
                     /prepeptide="core"
                     /locus_tag="PGW53_RS13095_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="3.30"
                     /molecular_weight="2300.5"
                     /monoisotopic_mass="2299.2"
                     /core_sequence="DATITTTWTVTTTSGFVSSVSNHC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNDVLELQKLEKETDGKGIAV"
                     /leader_location="[9875:9938](-)"
                     /alternative_weights="2318.5"
                     /alternative_weights="2336.5"
                     /alternative_weights="2354.5"
                     /alternative_weights="2372.5"
                     /alternative_weights="2390.6"
                     /alternative_weights="2408.6"
                     /alternative_weights="2426.6"
                     /alternative_weights="2444.6"
                     /alternative_weights="2462.6"
                     /alternative_weights="2480.7"
                     /alternative_weights="2498.7"
     misc_feature    9977..9994
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 24.87"
                     /tool="antismash"
     gene            complement(10001..12616)
                     /gene="lanKC"
                     /locus_tag="PGW53_RS13100"
     CDS             complement(10001..12616)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038151.1"
                     /locus_tag="PGW53_RS13100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_270354445.1"
                     /sec_met_domain="micKC (E-value: 1.1e-139, bitscore: 460.2,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 3.5e-19, bitscore: 62.5,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 8.5e-16, bitscore:
                     50.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEGNMLYHQYLKANSEYFGKQEMTLNTYEVNDIPDTYTVISDSNS
                     VWKYYHVKGVSLPEQGWKIHLTSLLEDAQSVLDRVARFCMGKKIEFKHLKDMHSFINMN
                     SKNANRASSGKFITVYPANEEIFVELLQDLSEITKDFKKGPYILSDKRWKNTNVFYRYG
                     GFKLIFNEYGEHCIRDESGNLIKDQRTPFYQTPDFVKDFDDYLNTINHSDDSEQQGESH
                     LAKYDIITALSYSNAGGVYLATRKKDNLKVILKEARPNAGLDGGPRDALERQKIEYDTL
                     KKLKNIHGVVNLIEYFQEWEHYFLVEEFIEGRDLRQWIAQEYPFFRDEDGDSICNHAKN
                     IKKILLQLFALIDQMHNNGVAMGDLQPANVMVTEDLTVKIIDFETAMPVESEEKPSMAT
                     IGFVSQEMKAGGSRDWFGLKRLVRYLALPVLSSDDMDGYLQDNHLYWIKMNYGESFYHF
                     ILELQKKCDDKIKGYHKYLPREINLYNKKRDINLYSMINKLIKGLENNLIDDERLVNGD
                     IRQFEMNGGKFNFLTGGSGAAYILTRCNSKSENVDNWIQSFLVDNLSSGDDNGLLTGKT
                     GMLALLYEKGYKETVLNELNVLRSNVNETTNISLRSGLSGIGLFLISLYFETESKEYLE
                     FAKEIEKLIDLNKVKDESLKVNDWMAVGIGLIDGLSGVSLFYSALYSATNNKRYLEEAE
                     LFLKKDLEKTKKDDVTGVLQTLDDRNRLLPYLSGGSIGVAASIWFLNHVSGQDLFKEEF
                     RAILNLSKIRCTISGGLFDGAGSFLLIPSMVDNRKMREGILMEVMDLLNIFLIEKNDYY
                     VYPGQFSYRLSDDVYTGSSGIVLALMGIVKSNPLYWLPLVNTDKFLAETKMKDIPVGIN
                     "
     gene            complement(12737..13390)
                     /locus_tag="PGW53_RS13105"
     CDS             complement(12737..13390)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001214697.1"
                     /locus_tag="PGW53_RS13105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC-2 transporter permease"
                     /protein_id="WP_071392185.1"
                     /transl_table=11
                     /translation="MRGLLLTNYYLVYRSFFAYTGLAILVSAVIFYFGDASMHRFVAML
                     IILFVVMPALEVIKYESKSGYDRYVLTLPVSRTNIVQSHYFFYLLIVVIGAVISYGIFV
                     VYSLGSDEPIDGIFNIVSFGTFIVLFAGAIVYPLLYMIGPEKSDAIVIGGAMGGLFATF
                     GLQSVVGYVAEQVPLSFLHINPSLYVPIIYLMIGVILYIISFFIASAIYHKKEF"
     gene            complement(13368..14240)
                     /locus_tag="PGW53_RS13110"
     CDS             complement(13368..14240)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017419297.1"
                     /locus_tag="PGW53_RS13110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_077721712.1"
                     /transl_table=11
                     /translation="MSNLLEIRNISKSFGHKAVLKDVTFNVPAGSIVGFIGDNGAGKST
                     TFKTILGLISQDRGKVKIFGEENLDKHIKFKEDIGVVFDAMNLPAHLTIKQLNHVFKKL
                     FDAWDQDHFYRLVHSFSLPMDKKVNTFSRGMSMKLSVAVALSHNAKLLLLDEATGGLDP
                     SSRDDLLNELKSFVSKSNGGILLSSHIMTDVEKIASHIIIMKDGEILLNEEKDKVLESY
                     TVIDVDEGQLAELDEDIVLAKRNHGSYWSVLVSDQQKLPNGVTANTISIEEISVFLTRS
                     ENIERSVTD"
     misc_feature    complement(14683..14696)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.12"
                     /tool="antismash"
     misc_feature    14794..14810
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 22.07"
                     /tool="antismash"
     gene            complement(14872..16674)
                     /gene="glmS"
                     /locus_tag="PGW53_RS13115"
     CDS             complement(14872..16674)
                     /EC_number="2.6.1.16"
                     /GO_function="GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA]"
                     /GO_process="GO:0006040 - amino sugar metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="glmS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388059.1"
                     /locus_tag="PGW53_RS13115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="WP_003156758.1"
                     /sec_met_domain="GATase_7 (E-value: 1e-15, bitscore: 51.1,
                     seeds: 307, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGIVGYIGQLDAKEILLKGLEKLEYRGYDSAGIAVANEQGVHVY
                     KEKGRIADLREVVDHTVESQAGIGHTRWATHGEPSFLNAHPHQSALGRFTLVHNGVIEN
                     YVQLKREYLENVELKSDTDTEVVVQMIEQFVAGGLSTEEAFRKTLTLLKGSYAIALFDG
                     ENTDTIYVAKNKSPLLIGLGDTFNVVASDAMAMLQVTNEYVELLDKEMVIVTKDEAVIK
                     NLDGEVMTRASYIAELDASDIEKGTYPHYMLKETDEQPLVMRKIIQTYQDENGRLAVAG
                     DVADAVAEADRIYIVACGTSYHAGLVGKQYIEMWANVPVEVHVASEFSYNMPLLSKKPL
                     FIFLSQSGETADSRAVLVQVKALGHKALTITNVPGSTLSREADYTLLLHAGPEIAVAST
                     KAYTAQIAVLAILASVAAERNGVDIGFDLVKELGIAANAMEALCDQKDEMEMIAREYLT
                     VSRNAFFIGRGLDYFVCVEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVFALAT
                     QEHVNLSIRGNVKEVAARGANTCIISLKGLEDADDRFILPEVNPALAPLVSVVPLQLIA
                     YYAALHRGCDVDKPRNLAKSVTVE"
     misc_feature    complement(17080..17095)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: medium, score: 25.01"
                     /tool="antismash"
     gene            complement(17106..18452)
                     /gene="glmM"
                     /locus_tag="PGW53_RS13120"
     CDS             complement(17106..18452)
                     /EC_number="5.4.2.10"
                     /GO_function="GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="glmM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388058.1"
                     /locus_tag="PGW53_RS13120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphoglucosamine mutase"
                     /protein_id="WP_007408011.1"
                     /transl_table=11
                     /translation="MGKYFGTDGVRGVANSELTPELAFKVGRFGGYVLTKDKQRPKVLI
                     GRDTRISGHMLEGALVAGLLSIGAEVMRLGVISTPGVSYLTKAMDAEAGVMISASHNPV
                     QDNGIKFFGGDGFKLSDEQEAEIERLMDEPEDKLPRPTGADLGLVNDYFEGVQKYLQFL
                     KQTADEDFTGIHVALDCAHGATSSIATHLFADLDADVSTMGTSPNGLNINDGVGSTHPE
                     ALSAFVKEKNADIGLAFDGDGDRLIAVDEKGNIVDGDQIMYICAKYLKSEGRLKDDTVV
                     STVMSNLGFYKALEKEEIKSVQTAVGDRYVVEAMKKDGYNVGGEQSGHLIFLDYNTTGD
                     GLLSAIMLVNTLKASGKTLSELADEMKKFPQLLVNVKVTDKYKVEENAKVKAVISEVEK
                     EMNGDGRILVRPSGTEPLVRVMAEARTKELCDEYVTKIVDVVRTEMGAE"
     gene            complement(18470..19909)
                     /locus_tag="PGW53_RS13125"
     CDS             complement(18470..19909)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388057.2"
                     /locus_tag="PGW53_RS13125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YbbR-like domain-containing protein"
                     /protein_id="WP_017419296.1"
                     /transl_table=11
                     /translation="MDKFLNNRWAVKIIALLLALLLYVAVNNNQAPTPKKPGESFFPTS
                     TTDEATLTDIPVKAYYDEANYVVTGVPQTVNVTIKGSTSAVKKARQTKNFEIYADMNKL
                     KTGTHKVELKAKNVSDGLTISINPSVTTVTIQEKTAESFPVEVEYYNKSKMKKGYTPQQ
                     PIISPKNVQITGSKNVIDNISLVKASVNLENANETIEKEVKVTVYDKDGNALPVDVEPS
                     VIKVTVPVASPSKKLPFKIERKGSLPDGVSVASIDSNPSEVTVYGPQDVLDSLEFIDGV
                     SLDLGKIDKDTDINADIPLPKGVTKVSPEKITLHVKVDSEDKKDFDNVGIKTVGLGGSQ
                     QIEFLDPESQAINITAKGSPANIKALKKSDIELYANVSDLDDGEHSVKLEVNGPQNVTW
                     SLSKDTVKIKLTSKKNTRSNKNNGGSADSGNKNGTSGDADKDKNKNREDDTDSDQNKSQ
                     NQDQNQDQDEDGSSADSSSTE"
     gene            complement(19902..20723)
                     /gene="cdaA"
                     /locus_tag="PGW53_RS13130"
     CDS             complement(19902..20723)
                     /EC_number="2.7.7.85"
                     /codon_start=1
                     /gene="cdaA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388056.2"
                     /locus_tag="PGW53_RS13130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="diadenylate cyclase CdaA"
                     /protein_id="WP_065180898.1"
                     /transl_table=11
                     /translation="MAFEDIPFLQYLGNAVDILLVWYVIYKLIMVIRGTKAVQLLKGIV
                     VIVLVRMASSYLGLSTLQWLMDQAITWGFLAIIIIFQPELRRALEQLGRGRFFSRSGTP
                     VEEAQHKTIEAITKSISYMAKRRIGALIAVERDTGMGDYIETGIPLNAQVSSELLINIF
                     IPNTPLHDGAVIMKNNEIAAAACYLPLSESPFISKELGTRHRAAVGISEVTDSLTIIVS
                     EETGAISVAKNGDLHRELTEEELKEMLEAEFKKNARDTSSNRWYWRGKKNG"
     gene            complement(20890..21516)
                     /gene="rsiW"
                     /locus_tag="PGW53_RS13135"
     CDS             complement(20890..21516)
                     /codon_start=1
                     /gene="rsiW"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388055.1"
                     /locus_tag="PGW53_RS13135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="anti-sigma-W factor RsiW"
                     /protein_id="WP_065180897.1"
                     /transl_table=11
                     /translation="MSCPEQIVQLMHKHLDGDILPEDENVLKQHLQSCGNCKRHFHEME
                     KSVALVRSTSHVTAPADFTAKVMANLPKEKKRASVKRWIKTHPMIAAAAVFVILMGGGF
                     FNSWHNDHNFSVSKQPNLIVQNHTVTVPEGETVKGDVTVKNGKLFIEGKVDGNVTVVNG
                     EKYMASAGQVTGQIEEINQLFDWVWYELKSAGQGVVSALDPNEDE"
     gene            complement(21530..22093)
                     /gene="sigW"
                     /locus_tag="PGW53_RS13140"
     CDS             complement(21530..22093)
                     /codon_start=1
                     /gene="sigW"
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388054.1"
                     /locus_tag="PGW53_RS13140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RNA polymerase sigma factor SigW"
                     /protein_id="WP_003156766.1"
                     /transl_table=11
                     /translation="MENLIKKRIKQVKKGDQNAFAEIVDLYKDKIYQLCYRMLGNVHEA
                     EDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRKKKPDYYLDAEVAGAEGL
                     TMYSQIAADGVLPEDAVLSLELSDTIQKKILKLPDKYRTVIVLKYIDELSLIEIGEILN
                     IPVGTVKTRIHRGREALRKQLRDL"
     misc_feature    complement(22226..22243)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 18.53"
                     /tool="antismash"
     tRNA            complement(22323..22394)
                     /anticodon=(pos:complement(158277..158279),aa:Gln,seq:ttg)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="PGW53_RS13145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /product="tRNA-Gln"
     gene            complement(22323..22394)
                     /locus_tag="PGW53_RS13145"
     assembly_gap    22432..22441
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
ORIGIN
        1 agccatcatt tccacaatgt ctccgtttac agagccttgt tggtccgaga tgactttgat
       61 acttgttttt tcattgtgtt ctgccgcttt tgcaaagcct ttcggcacgt atacaaaaac
      121 ggagactttg ccgctttcga caagctgttt cccttcttgg taactgccta tgtcttttac
      181 acggatgaga tcagtttgtt tcagcacgtc attctttaat acgtcgccca aagaactctc
      241 cgcgtgatcc gcattataaa acgcggtctg aaatggcttc actttcgaat cgccgtgaaa
      301 aaccgttcct aaaataaaaa tcatcagtgc cggaaacaga atcagtttta tatagaaaga
      361 ctttgctccg gccaataacc gaaaatctaa taagatcagc ctgaataata ttttcatgac
      421 gccccctatg aatcccgcag cgttttgccg gtgagccgga ggaaaatact ttccagattg
      481 gcttcctcga aatgaatgcc cttaatggtg ataccggtct tcctgatatc atccgcaata
      541 tcaaggatat tgcgatctgc cgcagagacg agcatcgtaa tggtctgctg gctgacagca
      601 gcctcggcaa caccgggaat gcagcggatt tttttaacgg catcatcatt cagcccctct
      661 gcattcacga tcagggtatc agaggctttg gctgactgct tcaattcgtc tttcgtcccg
      721 caggcaatga ttgagccgtg atccatgatc gccgcttttt cacagaggta ttcgacctct
      781 tccatgtaat gactcgtgta gatgacggtc atcccttttt cttgatttaa cgtcttcacg
      841 gtttcaagaa tatgatgtct ggattgcgga tcaattccga cggtcggttc atctaaaatg
      901 aatagtttcg gttcattcat tagcgcggct ccgatattca cccgtctttt catgccgcct
      961 gaaaactcag atatcctttg atttcgctgt tcctgtaatt cgatgatgtc cagcacttca
     1021 tcaacccgtt tacaaagttc cctaccggac agtccgtaca gactcccgaa aaaagccaaa
     1081 ttatcctttg cgcttaacgc ttgatataaa gcgatttcct gcgggacgac tcccatcact
     1141 ttttttatgg ccgcaggctg ctcctgtaat gaggttccgt caatgcagat tgttccgccc
     1201 gtcggcggga gcacggtgct gatcatcgac accgttgttg atttaccggc gccgtttggt
     1261 cccagcagac cgaatatctc gcctttttcg acgcacagtg atatatgatt gacagcggta
     1321 aaatcgccgt acttctttgt caaatccgtt aattcgagca ttcgtgcagc actccttgtg
     1381 tcatgtctgc atttattcta ctctcggcaa tccttgtttt ctattcactt tcgtaatcga
     1441 tatggatatt actttcgtca tatgtttagt gataaaaagg gagagaggag ggtgaagcgg
     1501 ggttatagca atttttgcaa atataaagta agctcggttc tgtttgacac ttcaagttta
     1561 tcgaggattc tggatacata gtttttcaca gtgccttcag tcagaaataa gtctgcggca
     1621 atgcgtttat tgcttttgcc ttccataatg tgtttcgcca catcaagctc tctcggcgtg
     1681 agaatctccg tcagctttga ctgcggctct tcctgcaccg cagggatctc catattgttc
     1741 agcgctttta cgacggaaac cgtgattttg ggattcagca tcatcttccc ttcataaacg
     1801 gcttgaaggg aggcgataat ttcatctgaa tcagcatcct tcaagagata gccgtcggct
     1861 ccgcttttca gcccggcaaa aatatagtga tcatcttcaa acgttgtcag aatgatgact
     1921 tttacggacg gatatcgcgc ttttaccgct tttgtcgttt cgattccgtc cataccgggc
     1981 attctgatat ccatcaaaat cacatcggtt tcggattgag aaagtatccg gagaacctct
     2041 tcgccgcaag aagcctctcc cgatatttga attccttcgt gaagactcag aatcattttc
     2101 agcccctctc tcacaatgga ctggtcgtct gcgatcatga cattcacttg attattcctc
     2161 cttgcatgga atccttattt tcacgtcaaa acctgtttcc ttcccagacg agaaaacagc
     2221 ctctccgcca agtgcggctg ctcttttctc aattcctttc agaccatttg attttatgat
     2281 cgttccgcag gctgagccgt tattatgaat atgcgccaat atcatgtttc ggtttttttg
     2341 aatccggaca gaaacatatg aagcatgtcc atgctttatc gcattcgtaa tcgtttcctg
     2401 aacggattga taaagacaat gcttcacatc cggctgttcc gcttctatgg ccgcatccat
     2461 ctccagctcg aagcgtatgc ctcccacctc ttgaaaatgg ctgaaaatgt cacggagctc
     2521 ttgctcaaac gcccgcccgg ccaaagagcc ctgcagcagc gtaaccgcct ggcgaagctt
     2581 taaaatggat tctttcgtaa gatcatgcgc cttatgaatg atctgcttca ctttgtccgg
     2641 ctgatgcccg gctgtcttcc cggcaaattc taaattcatt ttcagagcag ccagataatg
     2701 accgagagaa tcatgcagct cctgcgcaat tcttgttctt tctttcgtaa cggccagttc
     2761 ctcaatccgg tctgaatatt ccttcagtgt gtcattagcg gttttcagct ctcggttcag
     2821 caattctacc ttcgacttct cctgcaggtt tttccgatat aaataaatca ccgcaaacat
     2881 gatgaagtat ggcggcacga tatcactgac acccgctcct ccggcgtata aagctgctgc
     2941 aaatgcggcg gcattcaccg ttaacaaaac agccggaatc tgctgatcag taataagcac
     3001 ctccgccaat aaaagcacca ttacggcctg tgtccccaca ctatagacat tgtacaaaag
     3061 aactcccgcg ataacgttgc tcaggagaaa agagccttga tatacagcag gccttctctt
     3121 catatacagc ggccgcaggc agtcattagc cgtcagcatc atcacgagca cagacaaaaa
     3181 aaccttcagc tccccccggc cgggaggaag ctgaagaatc gcatgaaaga ttgatagtaa
     3241 tgcaaaaccc ctgatcagta acttcgtatg tgctatcttc atcgtattct ccttacagat
     3301 gagcggcggc ttttcgctcc acgttcagca catcatacag ctcatcaagc gaatgaattt
     3361 catgcgtcgg gatgattccg gactcatttg ctttctttcc gggattaaac cagcacgtat
     3421 caattcccgc catctgaccg ccttttatgt ccgcgctcag tgaatcgccg ataataagtc
     3481 cgccctcggc agaaaaaccg ggaattctcg caaacacgta atcaaagtat tccttcatcg
     3541 gcttttgaaa acccgtgtcc tcagatacaa acacatcttt aaagaacgga tacagaccgg
     3601 agtcgcccag ccgcttatat tgtgatcttg agacgccgtt cgtcacgatg tataaatcaa
     3661 ataaatgact cagccgttca atcagctcat aagctccgtc gatcatctgg tgcccttctt
     3721 ctaagtattg gcggtacgcc tgattcatca gcacgccgtc ggcttcgagg ccgtattctt
     3781 taaacaaaag ggcaaaccgt gtattcacca cttcatcgcg ggtcatttcc ccctcttcaa
     3841 acgccttcca cagcccttga tttaacgctt tataacgggc ttccacctct gccgtcagct
     3901 ccagctttga accttgaaac aatttttgaa gagcatcggt ttctgaagcg gtaaaatcca
     3961 gcagcgtatt gtctatatca aataataacg tacggtaatg actcatcgat gtttcccccg
     4021 gttctgcttt ttttaaccag tataccactc gcggacaagc cgaaaaagac acccctgtaa
     4081 gagaggtgtc tttttgaatt atacagcgtc ttctattttc gatttttcac caggcatgcg
     4141 cttgccgata ccgaacgcat aatagctgac cgtcacaatc gccaggaaaa tcaccccgac
     4201 aaccaaagaa atccgcgtat ctttgttaaa ccacatgccg atcaatacca tgagtaagaa
     4261 agcgatcgtc aaatagtttg taaacggcgc aaaaggcatt ttaaacgggt gctgatcaag
     4321 ctcagcgccc ttcgcccgtc tgaaaccgag atggctgatt aagataacaa accacggaat
     4381 cattccaggg agtacactcg cgctgtagac atagacaaat attttcggag gcgcgatgta
     4441 gttcagcacg acaccgatca caagtccgat taataccgca agcgtaccga atatcggcac
     4501 accgctcgat gaaactttct taaagaattt cggcgcctgt ccgttcacgc ccaacgtata
     4561 aagcatgcgt cccgcactga aaatcccgct gttacagccg gacatcgcag cggtaatcac
     4621 aacaaagtta atcaaaccgg ctgccgccgt aatcccgact ttcgcaaatg tcgaaacaaa
     4681 cggactgccg agtgagtgaa gctcattcca cggatacaca gtcacgatca cgaaaatcgc
     4741 accgatgtag aaaatcaaaa tccgccagat aatgctctga atcgcgcttc gcagcgtttt
     4801 ttgcggatct ttcgcttccc ctgccgtaat cccgatcagc tcaacccctt gataggccgc
     4861 aacaaccaaa gacaaagcaa agaaaaatcc tgaaaaacca tttgtaaaga aaccgccgtg
     4921 cgaccataaa ttagataatc cgatcgcatg ccctccgtta ccgaaaccga agaaaataat
     4981 cccgattccg gccacaatca tcagaataat ggtgacgatt ttgatcatgg caaaccaaaa
     5041 ttcaaactct ccgaaagatt ttactgaaat taaattcgcc gcaccgagaa tggccatggc
     5101 gataatgccg ggaatccatg ccggcagatc aggaaaccaa tatttcatat acgaaccgac
     5161 ggcgataatt tcagacatcc cgacgatcac ccattgaaac cagttgctcc acgccgtcat
     5221 atagccggct aacggatgta tatacttatg gccgaatgtc gcaaacgacc ctgtactcgg
     5281 ctctacatag agcatttcgc ccatcgcacg catgataaaa aagataaaga tacccgagat
     5341 cgcataagcc agcaggacag acggccctgt ccatccgatc gtgctggatg accccatgaa
     5401 taaaccgaca ccgatcgtgc cgcccagcgc aatcatctgt atatgacgcg cgcctaagcc
     5461 tctctttaat tctttgtttg ccacttcgct tcctcctctt aacagctctg atatatgtga
     5521 aataatgaag cagaaggtgc acctgttgaa cctaactcac tcttcatttc ccgcaatatt
     5581 agaaatattc tacctttcta ttgttatata atctccaatt tccttattcc atcataataa
     5641 attttcgtgg aaaatacaat tgtttttttc aggtaaacac cttgcaccct aaaccaacag
     5701 actaaaaata aagcgctttc atttttaatg aattatgaat attgagataa taaatgccgc
     5761 agcctccgag aaacaggatg tccctggaga aacatgttcc gccccctatt caatattatt
     5821 tttgctaagc agaatggcgt aaagtcttac tctcttccat tctcccttgt atacgccata
     5881 atcctgctta acccggcaaa aatcatgcat taatcgataa atgcctcatt cagccgcagc
     5941 aaaagccggc cgaacatttc tttttcatcg ccggaccaat cgtcaagcat acgatgatac
     6001 cgctcaaggc gcatcttttt atcagctttt aacctctgtt tgccaagctt cgtaatcgca
     6061 aacagactga cccgcccgtc agaaggatca gaaaaacgct ggatcagctc tttcgactcc
     6121 aaggccgctg cctggcgtga caatgtggaa atatccagct taaatgattc ggccaattcc
     6181 ttcacacgcg caggcccgaa ttcatccagc tgccgtagta acaaatacgc agccctttcc
     6241 agatgtccga ttttacggtc ggagttatca agataaacag ctctcctgat aaaagtggtg
     6301 agctcatatt caattaattc aatcggatct tgttttgaca aacgcctcac tccttacatt
     6361 gacaacagca acattagttg tataatacaa acatatgcac atttactcag aaaacatata
     6421 gaaatatttt gcatacatat atttgtatag tacaaatata tgtgccaaaa gtaaagaaac
     6481 ttatagaaac atcaagaaag ggggaagctg ctcttctcca aagaacagca ttgtcgtgaa
     6541 agtcatacgc atcatcttgc aaatcattat tttattcgca ttttccttta tcgggggagc
     6601 cgttcagcag ttctttcacc tgcccattcc cggaagcatc atcggtttga tcctgctgat
     6661 catatgttta tcggttaaga tcattcccgt caaaatgatt gaagacggag ccggattttt
     6721 gctgtctttt cttccgctct tattcattcc ggccatgacg ggcgtcatca attacccgtc
     6781 actgttttcc gccagcgggg ctgctctgtt tctgatcatc gtgctgagca ccatcgtcac
     6841 aatgattgcc gcagggtacg ccagccagct gttagagcac aaagccaatc agagaaagga
     6901 gaaaaagaag tgcagcaagc atgtatcgca atccttataa ttttgttcac ggccgccgcc
     6961 tatctggcta tggtgaaatt atatgtgcgc tttccatatc cctttctcat accggttttg
     7021 acgactacga ttttcattat cgccgtgctg cttgtttttc atatttcgta taaagactat
     7081 atgatcggcg gacaatggat taattcactg ctcggccccg ccgtggtggc tttggcatac
     7141 ccgctttata agcagcgccg ggtgttaatc aagtatatgt ttccgatcat cggcggcgtg
     7201 ttggccggtt tattctccgg aatgatcagc ggcctgctat ttgcagagct gttcggcatc
     7261 agccggagtt tgattttgtc aattatccca aaatcaatta cgacgcctgt cgccatacag
     7321 attgcgtccg gtatcggcgg tgtcccttcc atgacagtcg tgttcgtcat gatcgcaggg
     7381 ttttccggcg ttatcttagg accgctgctt ctcaagtgga tccgcatccg cagctcactc
     7441 gggaaaggaa ttgcattcgg aagcgcttcc catgcgctcg gcacctcaaa agcaatggag
     7501 tacggagaat taacggtctc catgagttct gtttccatga cgctctgcgc cgtgttagga
     7561 tcggtcttcg gccccgttgt agcatggatg tttcaaattt aaagctggcg gttctccgtc
     7621 agcttttttc atgtgcggat catctcattt ccttccatta ttacgtttca tttgtaagaa
     7681 taatggtaaa gtagaaaaca aggagggatt taatgatgac tgggacaatt ccgcaaaaga
     7741 aactgcttga tgggacaagc attcccgcga tcggcttcgg tacatacgct cttaatggaa
     7801 acaatggcgt tcatgccatt aacagcgcca ttgatatcgg ctaccgtctg attgataccg
     7861 cttataacta tgaaaatgaa gggacggtcg gagaagccat ccgcagaagc tctgttccga
     7921 gagaacagct atacgtgacg tccaagctgc ccgggcgcta ccatgactat gacaaagctg
     7981 tacaaaccat ccaagaatct ttataccgcg ccggtctgga ctactatgac ctgtatctcg
     8041 tccattggcc gaatccgaaa caagaccgct acacggaagc atggcaggca ctgattgatg
     8101 cgaaaaaatg gggcctgatc cgatccatcg gcgtctgcaa tttcctgcct gagcacatcg
     8161 aacggctcga acgtgaaacc ggcgtaaagc caggcatcaa ccaaattgaa ctgcatcccg
     8221 cttttaatca gcagcagcag cgccaatggc acgaagaaca gggcatcgtg acagaatcat
     8281 ggagtccgtt atcccgcgcc ggcgaagtat tgaacgatca aaaactcgga cagattgcgg
     8341 acaaatacga caaaaccatt tctcaagtca ttttgcgctg gcatatccag ctgggcgcca
     8401 tcccgattcc aaaatcagca tcgcccgagc gccagcttga aaacatctct gtttttgatt
     8461 tctcccttga tgaaaacgac atgagcatca tcgactcgct tacccgcccc gacggacgca
     8521 taaacggcca agacccggcg gagtatgagg agttttaaga aaacacataa agaaaagctg
     8581 acggcatcat tcgtcagctt ttttctgaat ctttatctag ttctcgctaa caaacacaat
     8641 gtacgatttc aatatggctt aaaggcctat caattttaac actcagtgtt agagccataa
     8701 ggagtacacc tttcatctat tatggctaac actgaatcct aaatggaata tttattttaa
     8761 gtactcaact cggctatttt tagatacgtt tagtccttat tttttcttta agacggctgc
     8821 aaaaaactct ccgttatttt tatattcctc gccattgaca tctgcataga ctttttcaag
     8881 gttaaaccct gcttcattca cttctttttc taaattttca atgctaaaat gctggttcca
     8941 ataattataa ttcactaatt tcccatcgtc aaaaatcaaa acattttttg ccaaagtaac
     9001 attatcagga tatttaattg cagcgtataa ggtcaaatgt tccttatccg atatcagact
     9061 gtcctttttt gataggaacc acattaaatt ctcttcaaat ttttcataac tcttctctga
     9121 taagacatct aatagaacta atcctccagg ttttaaaccg cgatagatgt tgttaagtat
     9181 ttttcttctg ttggtcggac taaaaacacc atagatttga taaatgagca gagctacatc
     9241 aaattcactt tcgatttcga gattcgtaat atcttcaatc ttataatcta tttgcaaatt
     9301 cattttatcc gcttcactaa tagcataatc gattgatttt ttattataat ctacaccagt
     9361 cacgttatag ccttttaatg ctaaattttg agaatagagc cccgggccac atcctaagtc
     9421 aataatttta ttattacatt ctactggtgc tatttttgta ataaaatcca cagtctcatc
     9481 aacaaatgag ctccctttgc tgccgccggg tatattctca tcaaaatgtg atttcaaaac
     9541 aagttcagct ctatctggat caagccatac ctcttgtgtg ccttcttcaa atggttcagg
     9601 gttttttgcc aattctaata actttttaat tgttgtcacc ttctatagtt ttttcatgat
     9661 ttgttaatta taattaagaa ctcttgggtg ctgattttaa ctacaagcac ccaagaaatg
     9721 ataaacttaa ggcttctccg acagtccaat acagtgttca tcatttatac ttcattaata
     9781 tttaatgaag caagattgtt ttaacaatga ttacttactg aagaaacaaa accgctagtt
     9841 gttgttactg tccatgtcgt tgtaattgtc gcatccacag ctataccttt accatctgtc
     9901 tctttctcta acttttgcaa ttccaaaaca tcattcactt ttctcacctc ctttcgagtg
     9961 ttaacagaca ttcatttatc atctaatggg gataatatta tcaatttatt ccaactggaa
    10021 tatctttcat ttttgtttcc gctaaaaatt tatctgtgtt gaccaatggt aaccaataaa
    10081 gtggattgct tttaacaatt cccattaatg ctaacactat acctgagctg cctgtataaa
    10141 catcatcaga taatctataa gaaaattgcc ccggataaac ataataatca tttttctcaa
    10201 ttaaaaagat attaagcaga tccattactt ccataagaat tccctcccgc atttttctat
    10261 tatcaaccat agaagggatt aaaaggaagc ttcctgcacc atcaaataaa cctccactga
    10321 ttgtgcagcg tatctttgat agatttaaaa tggctctaaa ttcttcttta aatagatctt
    10381 gtccacttac atggtttaaa aaccaaattg acgcagcgac tccaatagac cctccagaga
    10441 gatatggcaa taatcggttt ctatcatcta aagtctgtaa tacaccggtt acatcatctt
    10501 tttttgtctt ttccaagtct ttctttaaaa ataactcagc ttcctctaaa tatcttttat
    10561 tattggttgc tgaataaagc gctgaataaa acagagagac gccagataac ccatcaatta
    10621 aacctatacc taccgccatc cagtcattaa cttttaatga ctcgtcttta accttattta
    10681 ggtcaatcaa tttttctatc tctttcgcaa actccaagta ttctttactt tccgtctcaa
    10741 aatataaact gattaagaac aggcctattc ctgaaagacc tgatcgtaaa gaaatgttgg
    10801 ttgtttcatt tacattactt ctcagaacat tcaattcatt taaaacagtt tccttgtacc
    10861 ccttctcata aagcagagcc agcattcctg tttttccagt taataaacca ttatcatcgc
    10921 cactcgatag gttatccacc aaaaaacttt gaatccaatt atctacattc tcagacttcg
    10981 agttacatct ggtaagaata taggcagcgc cactcccccc agtgagaaag ttgaattttc
    11041 ctccgttcat ttcaaactga cgaatatcac cgtttacgag cctttcatca tctattaaat
    11101 tgttttctag accctttatc aacttattaa tcatggaata taagttgata tcccttttct
    11161 tgttataaag gttaatctct ctgggaagat atttgtgata accttttatt ttatcatcac
    11221 attttttttg caactctaaa atgaaatgat aaaatgattc tccataattc atctttatcc
    11281 agtataaatg gttatcttgc agatacccat ccatatcgtc tgatgagagc actggcagtg
    11341 ctaaatatct tactaatctc tttaacccaa accagtctct agaaccacct gccttcattt
    11401 cttgagaaac aaacccgatt gttgccatac taggtttttc ttcagactct acgggcattg
    11461 cagtctcaaa atctattatc ttaacggtta aatcttcagt taccatcaca tttgctggct
    11521 gcaaatcacc catagcaact ccgttattat gcatttgatc tatcagagca aagagttgta
    11581 acaatatttt ttttatattc ttagcatgat tacatatact atcgccatct tcatctctaa
    11641 agaatggata ctcttgtgca atccattgtc tcaaatctct tccttcaatg aattcctcta
    11701 ctaaaaagta atgttcccat tcttggaagt actcaattag attgaccacg ccatgtatgt
    11761 tcttaagctt ttttaaagta tcatattcaa ttttttgcct ttctaacgca tctctgggtc
    11821 ctccatctaa accagcattt ggtctggctt ctttaagaat aactttcaag ttatctttct
    11881 ttcgagtcgc aagatatacc cctcctgcgt tactgtagct cagtgcagta atgatatcat
    11941 acttcgctaa atggctttcc ccctgttgtt ctgagtcgtc agaatgattg atcgtattaa
    12001 gataatcatc aaagtctttt acaaaatcag gggtctgata aaagggtgtt ctttgatcct
    12061 taattaaatt accactttca tccctaatac agtgctcacc atattcatta aaaataagct
    12121 taaatccgcc atatctgtaa aatacattag tatttttcca cctcttatca ctgagtatat
    12181 aggggccttt tttgaaatcc tttgttattt cagataaatc ttgcaacaat tcaacaaaga
    12241 tttcttcatt agccgggtac accgttataa acttgccgga agaagctcga tttgcatttt
    12301 ttgaattcat attaataaaa ctatgcatat cctttaggtg tttaaattca attttcttac
    12361 ccatacaaaa gcgggcaacc ctatccaata cactttgtgc gtcctctaac aatgaagtta
    12421 aatgaatttt ccacccctgc tctggtaacg atacaccctt aacatgataa tatttccata
    12481 ctgagttgct atctgagata acagtatatg tatcagggat gtcattcact tcatatgtat
    12541 tcagtgtcat ctcttgtttc ccaaaatact cggaatttgc cttcagatat tgatgatata
    12601 gcatgttgcc ttccataaaa gcccccccat ttttatatgc taaatattaa ccctcaaggt
    12661 cacaaagttc tttatatgca aagacaacac cttatcctgt tataacttga tcagcataaa
    12721 atcaatacac acgctgctaa aattcttttt tatgatatat agctgaggca atgaaaaatg
    12781 aaatgatata taagataacg ccgatcatga gatatataat cgggacatat aaagaaggat
    12841 ttatgtgcaa aaatgacagc ggtacttgtt ctgctacata cccaacgaca ctttgcaatc
    12901 caaaggtagc aaaaagtccc cccattgccc ctccaatcac gatagcatcg gatttttccg
    12961 ggcctatcat gtagagaaga ggataaacga ttgcaccggc aaagagaacg atgaacgttc
    13021 caaaagagac aatattaaat atgccgtcaa ttggttcatc agaacccagg ctgtatacaa
    13081 cgaaaatacc ataagatatt acagctccga tcacaacaat caaaagataa aagaaatagt
    13141 gactttgaac aatatttgtt ctgctgaccg gtaaagtcag gacatacctg tcatagccag
    13201 acttgctctc atactttata acctcaagtg cgggcataac gacaaacaaa ataatcagca
    13261 tagcaacaaa acgatgcatt gaagcatccc caaaataaaa aatgactgct gataccaata
    13321 tggccaaccc tgtgtatgca aagaaactcc gataaaccaa gtaatagtta gtcagtaaca
    13381 gacctctcaa tgttttcact cctcgttaaa aagacgctga tttcttctat ggaaatggtg
    13441 ttggccgtta cgccattcgg caacttctgt tgatccgata caagcacact ccaataagat
    13501 ccatgattcc tttttgctag aacgatatct tcgtcaagct cagccaattg gccttcatca
    13561 acatctataa cggtatagct ttcaagaacc ttatctttct cttcatttaa taaaatttcg
    13621 ccatctttca taataatgat atggctggct atcttctcga catcagtcat aatgtgcgat
    13681 gaaagtaaaa taccgccgtt gcttttactc acaaagcttt ttaattcatt taacagatca
    13741 tctcttgaag aaggatcaag ccctcccgtt gcttcatcca gaagtaataa ttttgcatta
    13801 tgcgacaaag caacagctac ggataacttc attgacatgc cgcgcgagaa tgtattcact
    13861 tttttgtcca taggtaaaga gaaagaatga accaaccggt aaaaatgatc ttggtcccaa
    13921 gcgtcgaata gtttcttaaa tacatgattc agctgcttta tcgtaaggtg cgcgggcaga
    13981 ttcatcgcat caaatacgac cccaatatct tctttaaact ttatatgttt atccagattc
    14041 tcctcaccaa agattttcac ttttcctcta tcttgagaga ttaaccctaa tatcgtttta
    14101 aatgttgttg atttgcctgc gccgttatca ccgataaaac cgacaattga tccggcaggc
    14161 acattgaatg taacatcctt taaaacagct ttatgaccaa aagatttgct gatgtttctg
    14221 atttctaaaa gatttgacat cattccactc ctatcattgt tgtcaggact tttttaagaa
    14281 ttgaaccgga ttattgcaaa aatgttgtga ttttcatatc tagtctaggt attcataatg
    14341 gatcaggagc cggcaaatac aaaagggatt ttaaagttct aagcataata tggaagtgta
    14401 atcgattgat taggtttata taatgggata ttcatgatga aaactgctgg aggtgactta
    14461 catgctggaa aagaaaatgt gtattctata atctatatat gtagtctcat cagataacag
    14521 atttattgtc taattgagta gcccgttcaa gagtgaagta tgtcctaaaa agtaatcaga
    14581 catgggaata aaacaccaaa caaatactta ttcaaaaacc aataattgat cgctaccatt
    14641 ccttactaat ggttacattt atgggtttaa actggaatat atttatatta taaaataggc
    14701 gttacttctt ttcaatatat atatggggat ttctttataa atataaaatt cttcagttta
    14761 tcaacaggcg aacacttctt attttcatac taaaaacccc tctggtttat ctaaaaccag
    14821 aggggtcaaa ctttccgact atattttaag tttaccgtga attatttatt cctattccac
    14881 agtcacactc ttcgcaaggt tgcgcggttt atcaacgtca cagccgcggt gcagtgcagc
    14941 gtagtaagcg atcagctgca atggcacaac agaaaccagc ggagcaagcg cagggttgac
    15001 ttccggcagg atgaatctgt cgtctgcgtc ttctaagcct ttcagcgaga tgatgcaagt
    15061 gttggcgccg cgggctgcga cttccttcac attaccgcgg atgctcaggt tgacgtgttc
    15121 ttgtgtcgca agcgcaaaga ccggtgttcc ttcttcaatc agagcgattg ttccatgctt
    15181 cagctcgccg ccggcgaagc cttccgcctg gatgtaagaa atctctttca gcttcagggc
    15241 gccttcgaca cacacgaagt agtcaaggcc gcggccgatg aagaaagcgt ttcttgaaac
    15301 agtcaggtac tcacgtgcga tcatttccat ttcgtccttc tggtcgcaga gggcttccat
    15361 ggcgtttgcc gcgataccta attctttgac taaatcaaaa ccgatatcaa cgccgttgcg
    15421 ttctgctgca acggacgcaa ggatcgcgag gacggcaatc tgagccgtat acgcttttgt
    15481 tgatgcaacc gcgatctcag ggcctgcgtg cagaagcaat gtgtaatccg cttcacggga
    15541 aagcgttgat cccggaacgt ttgtaatcgt cagcgctttg tgacccagcg ctttgacttg
    15601 aacaagcacg gcgcggctgt ccgctgtttc tccgctttga gaaaggaaga taaagagcgg
    15661 cttcttagac agaagcggca tgttataaga gaattcactc gctacatgca cttcaaccgg
    15721 tacgtttgcc cacatttcaa tatattgttt cccgacaaga ccggcatggt agctcgttcc
    15781 gcaagccacg atatatatgc ggtccgcttc cgccacggcg tcagcgacat cgccggccac
    15841 ggccagtctg ccgttttcgt cctgatacgt ttggatgatt ttgcgcataa caagcggctg
    15901 ctcatccgtt tcttttaaca tgtagtgagg gtatgtgcct ttttcgatat cactggcgtc
    15961 aagctcagcg atataagacg cacgtgtcat gacttcaccg tcaaggtttt taatcacggc
    16021 ttcgtctttt gtcacgatca ccatttcttt gtccaaaagc tcaacgtatt cattcgttac
    16081 ttgaagcata gccatcgcgt cagatgccac gacgttaaac gtatctccaa ggccgattaa
    16141 cagagggctt ttgttttttg caacgtaaat ggtgtctgtg ttttcaccgt caaataatgc
    16201 aattgcgtaa gagcctttta acagagtcag tgttttgcgg aacgcttctt ctgtactaag
    16261 tcctcccgcc acaaattgct cgatcatttg aacgactact tcagtgtccg tgtcgctttt
    16321 cagttcaacg ttttcaagat attcgcgctt cagctgaaca tagttctcga tcacaccgtt
    16381 atgaacaagt gtaaagcggc cgagtgcgct ttgatgcggg tgagcgttca ggaagcttgg
    16441 ttcgccgtga gtcgcccagc gtgtatggcc gattcccgct tgagattcaa ccgtgtgatc
    16501 caccacttca cgaaggtcgg cgatgcggcc tttttctttg tacacatgca cgccctgctc
    16561 attcgccaca gcgataccgg cagagtcata accgcggtac tcaagcttct ctaatccttt
    16621 taacaaaatc tctttcgcat caagctgacc gatgtaacct acaattccac acatattttc
    16681 ttcctcctaa aggtgcaaaa ggagacgaag aaagtcaaat tacaagggga ctttcaatcg
    16741 tcccctccca catgtttttt tggaagatca tgtgatttcc ctttgttcgg agagtcgccc
    16801 ctccggtttg aagaaatcct tacggctgtg atctaaatga atcagccggg aggcatccgc
    16861 cgaaaattcg ataacctcca tcctcgtcaa ctaagccgtt tttcgggcgc ttagttcggg
    16921 cgctgtaatt ataaaagatg caaacaatcc cgcctttcct gcaagtgaaa aacaaaggct
    16981 gaacaagctt gattttacag catgtgccaa ggacggtcaa ttattttttg ccgccccggc
    17041 atcatgttta ctatcatatt atgctgatcg cacttgtctt gttcgctctc tgcttataaa
    17101 cttcgctact ccgctcccat ttctgtccgc acgacatcca cgatttttgt gacatattcg
    17161 tcacaaagct cttttgttct cgcttcggcc atcacgcgga cgagcggttc ggtgcctgac
    17221 gggcgcacta aaatccggcc gtctccgttc atttcttttt ccacttcaga aataacggcc
    17281 ttcaccttag cgttttcttc taccttatat ttatccgtca ctttcacatt cactaagagc
    17341 tgcgggaatt ttttcatttc atccgcaagt tctgaaaggg ttttgccgga cgccttcagc
    17401 gtatttacaa gcatgatcgc ggacaagaga ccgtcgccgg tagtattgta atcaaggaaa
    17461 ataaggtgcc ctgactgctc gccgccgaca ttatagccgt cttttttcat cgcttctacg
    17521 acatagcggt cgccgactgc cgtttgaacg cttttgattt cttctttttc aagcgctttg
    17581 tagaaaccga ggttgctcat cacggtcgat acgacggtat catccttcag acggccctct
    17641 gatttcaaat acttcgcgca tatgtacatg atttgatcac cgtcgacgat gtttcctttt
    17701 tcatcaacgg caatgaggcg gtcgccgtct ccgtcaaacg caaggccgat atcggcgttt
    17761 ttttctttga cgaaagcact cagcgcttcc gggtgtgtag aaccgacgcc atcattaatg
    17821 tttaatccgt tcggagacgt ccccattgta gatacgtcag catcgagatc ggcaaaaagg
    17881 tgcgtcgcaa tggaagatgt cgcaccatgg gcgcagtcaa gcgctacatg aatgcctgtg
    17941 aaatcttcgt ccgccgtctg ctttaaaaat tgcagatact tttgaacgcc ttcaaaataa
    18001 tcgttcacaa gcccgaggtc cgcgcctgtc ggtctcggca gcttatcttc cggttcatcc
    18061 atgagacgtt caatctcggc ctcctgctca tcagaaagct taaagccgtc ccctccgaaa
    18121 aatttaattc cgttatcctg tacggggttg tgagaagcgg agatcatgac gcccgcctca
    18181 gcatccatgg ctttcgttaa ataggatacc cccggcgtag aaataacgcc gaggcgcatc
    18241 acttcagctc cgatcgataa aagtccggcg acaagggctc cctccagcat atgtccggag
    18301 atacgtgtat cacggccgat cagcactttc gggcgctgct tatctttggt caggacataa
    18361 ccgccaaaac gcccaacttt aaaggccagc tctggcgtaa gctcgctgtt ggcaacacct
    18421 cttacaccat ctgttccaaa atacttgccc attttgtatc gctccttttt cattctgttg
    18481 aagaagaatc agcgcttgat ccgtcttcat cctggtcttg attttgatcc tggttttgac
    18541 ttttattctg atcgctgtca gtgtcgtctt cccggttctt gttcttgtct ttgtctgcgt
    18601 ctccgcttgt gccgttctta ttgccggaat cagcggaacc gccgttattt ttatttgaac
    18661 gtgtgttttt cttagaagtc agcttgatct taaccgtgtc ttttgacagg gaccatgtga
    18721 cgttttgcgg gccgtttact tcaagcttta cagagtgctc tccgtcatcc aagtccgaga
    18781 cattggcata cagttcaatg tctgactttt tcaacgcctt aatgttggcg ggagagcctt
    18841 tggccgtaat atttatcgcc tgcgattcag gatcgagaaa ctcaatctgc tgtgagcctc
    18901 ccagtccgac cgtcttgatt ccgacattgt caaaatcctt tttgtcttca ctgtccactt
    18961 taacatgaag cgtgattttt tccggtgata ccttagtgac acccttagga agcgggatat
    19021 cggcattgat atcggtatct ttatcaattt tgcctaaatc aagagatacg ccgtcaataa
    19081 attccagtga atccagcaca tcctgcgggc cgtaaaccgt cacctcactc ggattcgagt
    19141 caatgctcgc aacgctcacc ccgtccggaa gacttccctt cctttcgatt ttgaaaggaa
    19201 gctttttgct cggactggct acgggaaccg tcactttaat gactgacggt tcaacatcaa
    19261 caggaagtgc gttgccgtct ttgtcataga cggtcacctt cacttccttt tcaatggtct
    19321 catttgcatt ttcaaggttc acggatgctt ttacaagtga aatgttatca atcacatttt
    19381 tcgaacctgt aatctgcacg tttttcgggc tgataatcgg ctgctgaggg gtgtatccct
    19441 ttttcatttt gcttttattg tagtattcaa cttccacggg aaaactctca gccgtttttt
    19501 cctgaatcgt aaccgtcgtg actgacgggt taatggagat cgtcagtccg tccgatacgt
    19561 ttttcgcttt caattcgacc ttatgagtcc cggtcttcag cttattcata tcggcgtata
    19621 tctcaaaatt cttcgtctgt ctcgcctttt tcaccgcgct tgtcgagcct ttaatcgtga
    19681 catttacggt ctggggcaca ccggtgacga catagttcgc ttcatcatag tatgctttta
    19741 caggaatatc agtaagcgta gcctcgtcag tcgttgatgt cggaaaaaag gattcccccg
    19801 gctttttcgg agtcggcgcc tggttgttgt taaccgcaac gtaaagcagc agcgccaaga
    19861 gcaatgcaat gatctttaca gcccagcggt tgtttaagaa tttatccatt tttcttgccc
    19921 ctccagtacc agcggttaga agaagtgtct ctggcgttct tcttaaactc ggcttcaagc
    19981 atttctttca gttcttcttc cgtcaattct ctgtgaaggt ctccgttttt ggccacactg
    20041 atggcgcccg tctcttcaga tacaataatg gttaagctgt ccgtcacttc actgatgccg
    20101 acagccgctc tgtgacgcgt ccccagctcc tttgaaataa acgggctttc agaaagcggc
    20161 agataacagg ctgccgccgc aatctcgtta tttttcataa tgaccgctcc atcatgcagc
    20221 ggtgtattcg ggatgaagat attaatcaaa agctccgagc tgacctgcgc attaagcggg
    20281 atgcccgtct caatataatc gcccattccc gtatcgcgct caacggcgat gagtgcgccg
    20341 atgcggcgtt tcgccatgta gctgatcgat tttgtaatcg cttcaattgt cttatgctgc
    20401 gcttcttcca cgggggttcc gctcctggaa aagaaccggc cccgtccgag ctgttcaagc
    20461 gcccgtctca gctcaggctg gaatataatg atgatcgcta aaaatcccca tgttatcgct
    20521 tggtccatca gccactgaag cgtgctgagt cccaaatatg aactggccat ccggaccaat
    20581 acgatgacga cgattccttt taaaagctga accgccttcg tcccgcgtat gaccatgatt
    20641 aatttatata tcacatacca aacaaggaga atatcaacgg cattgccgag gtattgcaaa
    20701 aatgggatgt cctcaaaagc catttcctcg tcctccaaga attcagtcat ttcgtttttt
    20761 ccgttatgaa ttgtgctgca tgagcaatat gtacatcata tagcgtgctc attataccac
    20821 attttgattt ctcaagtgaa atgggccggc acggcgatgc acaaaaaaag agtaaagcga
    20881 ttatacgctt tactcatctt cattcgggtc caaagcgctt acgacgccct ggcccgccga
    20941 tttcagttcg taccagaccc agtcaaacaa ttggttaatc tcttcaatct gcccggtgac
    21001 ttgtccggct gaggccatgt atttttctcc gttgacgacg gtcacattgc cgtcgacttt
    21061 tccttcaatg aacagcttgc cgttttttac tgtgacatcg ccctttacgg tctcgccttc
    21121 agggacggtg accgtgtgat tctgcacgat aaggttcggc tgtttggaca cactgaaatt
    21181 gtggtcatta tgccagctgt tgaaaaaacc gccgcccatt aaaatcacaa aaaccgctgc
    21241 ggctgcaatc atcggatgag ttttgatcca tcgttttaca gaagcgcgtt ttttctcttt
    21301 tggaagattc gccataactt tggcagtaaa atcagcaggg gccgtgacat gcgatgtgct
    21361 tcggacgagt gctacggatt tctccatttc atgaaaatgc cgtttgcaat tcccgcatga
    21421 ctgcaaatgt tgttttaata cgttttcatc ttcaggaagg atatctccat caagatgctt
    21481 atgcataagc tgcacgatct gttcaggaca gctcatttca tcaccccact taaagatccc
    21541 tcaattgttt tctaagagcc tctctgcctc tgtgtatcct tgtcttgacg gtgccgacag
    21601 ggatattcag aatctccccg atttcaatta aagagagttc gtcaatatac tttaatacaa
    21661 taactgttct gtacttgtcc ggcagcttta aaatcttttt ctgaattgtg tccgacagct
    21721 ccaatgacaa tacggcgtct tcagggagaa ccccgtctgc ggcgatctgc gaatacatcg
    21781 tcagcccttc tgctcccgct acttctgcgt ccagatagta atcaggcttt ttcttgcgga
    21841 tgcggtcaat ggtcaggttg gtcgcaattc tgtaaagcca cgttgaaaac tttctgttga
    21901 tatcgaaact gtcgatattg acatacgctc tgataaaagc ttcctgcgca atatcttccg
    21961 cttcgtgaac attgccgagc atgcggtagc aaagctggta aatcttatct ttataaaggt
    22021 caacgatttc tgcaaacgca ttttgatcgc cttttttgac ttgcttgatt ctttttttaa
    22081 tcaggttttc catgttttat cttacctctg cccttcaccg gtctgtatct atacgttgat
    22141 tgttttaaaa ggtttcattt ttttattaca tttattttac caaatttcag gcagggtgta
    22201 gatggaaaat acagaatata ctgccttaac agcagcttaa aaatagtata tctgatgaac
    22261 aatcagaaat cgaaacaaaa tgctgataaa aaaagacacc tttatgcaaa aggtgtctga
    22321 tactgggcta gctggattcg aaccaacgca tgacggagtc aaagtccgtt gccttaccgc
    22381 ttggctatag cccaaaaatg gtggaggggg gcagattcga actgccgaac cnnnnnnnnn
    22441 nctgtgtctg cgtcgagctg acaaaagtta ttatatacag gttgtaccct atttgtaaag
    22501 agaaaaatta ttttttttat tttcaaactt ttttacccgt tttttaactg aaaaactcat
    22561 ccctcccctc ttatttcatt tatgatgaaa gtatcaaaat attgaaggga atggac
//
