LOCUS       NZ_JAQDYA010000012     23903 bp    DNA     linear   CON 22-FEB-2024
DEFINITION  Lactococcus lactis strain AM113-80 PF3HH22005.Scaf12, whole genome
            shotgun sequence.
ACCESSION   NZ_JAQDYA010000012
VERSION     NZ_JAQDYA010000012.1
KEYWORDS    WGS; RefSeq.
SOURCE      Lactococcus lactis
  ORGANISM  Lactococcus lactis
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Lactococcus.
REFERENCE   1  (bases 1 to 36136)
  AUTHORS   Lin,X., Hu,T., Chen,J., Liang,H., Zhou,J., Wu,Z., Ye,C., Jin,X.,
            Xu,X., Zhang,W., Jing,X., Yang,T., Wang,J., Yang,H., Kristiansen,K.,
            Xiao,L. and Zou,Y.
  TITLE     The genomic landscape of reference genomes of cultivated human gut
            bacteria
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 36136)
  AUTHORS   Zou,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-NOV-2022) BGI Reaserch, BGI-Shenzhen, Beishan
            Industrial Zone, Shenzhen 518083, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. v2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100x
            Sequencing Technology             :: MGI
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/22/2024 02:49:03
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,400
            CDSs (total)                      :: 2,354
            Genes (coding)                    :: 2,325
            CDSs (with protein)               :: 2,325
            Genes (RNA)                       :: 46
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 29
            CDSs (without protein)            :: 29
            Pseudo Genes (ambiguous residues) :: 0 of 29
            Pseudo Genes (frameshifted)       :: 9 of 29
            Pseudo Genes (incomplete)         :: 18 of 29
            Pseudo Genes (internal stop)      :: 7 of 29
            Pseudo Genes (multiple problems)  :: 4 of 29
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:07:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 12162
            Orig. end                         :: 36065
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAQDYA010000012.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23903
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RaS-RiPP"
                     /region_number="1"
                     /rules="(PF04055 and TIGR01716)"
                     /tool="antismash"
     cand_cluster    1..23903
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF04055 and TIGR01716)"
                     /kind="single"
                     /product="RaS-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23903
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13903](+)"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13903
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
     gene            97..942
                     /locus_tag="PGT72_RS11275"
     CDS             97..942
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003132644.1"
                     /locus_tag="PGT72_RS11275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)H-binding protein"
                     /protein_id="WP_058224270.1"
                     /transl_table=11
                     /translation="MKYLVTGATGGYGTYALGFLKELVPISDIAVLARTEEKAAPLKAA
                     GFDVRLADYSDLTALEQAFTGIDRLLFVSGAPGNRQAEHQNVVDAAKSAGISYIAYTSF
                     PQAERATSDLAADHIYTEKAIKKSGIAHTFLRNNWYFENEMPIIAAALSTGKFVYNAPT
                     GKVGWALKREYAEVGAKALAGADFPEVLELSGKILTYAELAQALKAVSDKEFEVVAADD
                     KTFVSHLVETGLPDFVAELFLGFQKDIEAKDLDVESKDFEKVLGHSLTDTKEALKELLA
                     "
     gene            complement(976..1482)
                     /locus_tag="PGT72_RS11280"
     CDS             complement(976..1482)
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015427194.1"
                     /locus_tag="PGT72_RS11280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="WP_017865183.1"
                     /transl_table=11
                     /translation="MMKYTFEIDLDRYKNLAQQKQKTHKKFLAGLAKKPPKQLDKIVKE
                     VHEEVFLEIDCTKCANCCKTLGPLWTEADIERVAKHLKMKVSDFEAAYLRTDEDGDKVF
                     QTMPCQFLGSDNLCSIYEVRPKACREFPHTDRKKIYQINNLTIKNTLYCPAAYEFVEKL
                     SYRLK"
     misc_feature    1620..1633
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.23"
                     /tool="antismash"
     misc_feature    1621..1634
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.21"
                     /tool="antismash"
     gene            1826..3172
                     /locus_tag="PGT72_RS11285"
     CDS             1826..3172
                     /EC_number="5.3.1.9"
                     /GO_function="GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /locus_tag="PGT72_RS11285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="WP_010906353.1"
                     /transl_table=11
                     /translation="MAHIKFDYSKLTPFVAENELDEIQWQIDGAAKLLHEGKGAGSDYI
                     GWLDLPEDYDKEEFARIQKAAKKIQSDSEVLIVIGIGGSYLGARAAIDFLSNSFVNLQT
                     AEERKAPRILYAGNSISSSYLADLVDYVADKDFSVNVISKSGTTTEPAIAFRVFEEMLV
                     KKYGREEANKRIYATTDKEKGAVKVNADANNWETFVVPDSVGGRFSVLTAVGLLPIAAS
                     GADITALMEGANAARKEYTSTNVHENDAYAYAALRNILYRKGKFSEILINYEPSLQYFS
                     EWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQWIQEGTRTVFETAIRIEKPRKNINI
                     PELDADLDGLGYLQGKDVDFVNKKAADGVLLAHTDGNVPNMIVTLPEQDEFTLGYAIYF
                     FELAIGVSGYLNGINPFNQPGVEAYKKNMFALLGKPGFEELSKELNDRL"
     gene            complement(3268..4374)
                     /locus_tag="PGT72_RS11290"
     CDS             complement(3268..4374)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836082.1"
                     /locus_tag="PGT72_RS11290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="anti-sigma factor C-terminal domain-containing
                     protein"
                     /protein_id="WP_017865182.1"
                     /transl_table=11
                     /translation="MHTLLIFPYLVLAITLFFGLIRLFIFVINKTRHKLQKTESISNLN
                     KDFHNFALKTKIKRWGLTTWIALTVFSAFIVVGWRVNSAIMEKNFFKTFDYSTAIFTAS
                     APNIAYNNQIIDDYGVFSSNLHSDTYKDIDGYHVPWESYNFSFNVSNVGGLSLNTLSPS
                     VNSNAYFTQTTNQKIASFFSTNANYKSKDYNGILPTHDADKISQLSNHVAEVAVTFDKA
                     YSYNEIQKMIPENLLINWYWIGYNDSKSLDAAGQTNWFGLMSNSNYAENGNNSKLTGKL
                     DNTTYQDFKKSVAAIAKKNQITINDFSPSKDALKQVKKYPTLKSAKFSGVILTGQTKNF
                     ANFDKNSWVYASNVGLTVELRPDIKPLK"
     gene            complement(4398..4892)
                     /locus_tag="PGT72_RS11295"
     CDS             complement(4398..4892)
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010906351.1"
                     /locus_tag="PGT72_RS11295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_017865181.1"
                     /transl_table=11
                     /translation="MVNLKEYENDVNDYAIEITKYLISRGSQLVDAEDAVQDTLVKILS
                     LDIFIEPDKLRAFMYRTSIRTYINSYNRSKHYQKIIKNLEKELETAAFLVESSPLPKII
                     EQLPPYYKELLNAYYYENCSTKQLAEYFECSLSKIKIDLYRARKKLKKQLEKAGYDQWL
                     L"
     gene            5080..6306
                     /gene="lmrP"
                     /locus_tag="PGT72_RS11300"
     CDS             5080..6306
                     /codon_start=1
                     /gene="lmrP"
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836081.1"
                     /locus_tag="PGT72_RS11300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="multidrug efflux MFS transporter LmrP"
                     /protein_id="WP_012898648.1"
                     /transl_table=11
                     /translation="MKEFWNLDKNLQLRLGIVFLGAFSYGTVFSSMTIYYNQHLGSAIT
                     GILLALSAVATFVAGILAGFFADRNGRKPVMVFGTVIQLLGALLAIASNLPGHVNPWST
                     FIAFLLISFGYNLVITAGNAMIIDASNAENRKVVFMLDYWAQNLSVILGAALGAWLFRP
                     AFEALLVILLLTVLVSFFLTTFVMTETFRPIVKAKEEAENIFQAYKTVLQDKTYMIFMG
                     ANIATTFIIMQFDNFLPVHLSNSFKTITFFGFEIYGQRMLTIYLILACVLVVLLMTTLN
                     RLTKDWSHQKGFIWGSLFMAIGMIFSFLTTTFTPIFIAGIVYTLGEIVYTPSVQTLGAD
                     LMNPEKIGSYNGVAAIKMPIASILAGLLVSISPMIKATGVSLVLALTEVLAIILVLIAV
                     NRHQKTKIN"
     misc_feature    complement(6360..6373)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.11"
                     /tool="antismash"
     gene            6390..7610
                     /locus_tag="PGT72_RS11305"
     CDS             6390..7610
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015427192.1"
                     /locus_tag="PGT72_RS11305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_012898647.1"
                     /transl_table=11
                     /translation="MKDFFGLHPTLKIRLIMNFFGTLCFSTVGGSMTIYYNKYMGAGIT
                     GLLLVISSVMVFLVGLYAGHLSDVQGRRPVMIFSTAITGFGGALATFANSSFYFNPWVT
                     FLGFLIINFGFGFFNTASQAMIVDLTTSGNRRVVYSIQYWIINFAIMIGSGLSGWFFRD
                     YLVWLLLAITIEEIVSCLVVIFWIDESFNPDTQQHKQESNIIKAYFTVAKDRIFMYYLF
                     ASVFIAMIFNQIDYYLPVHLSDSFRTARIFGIEVYGQRMLTIFLMVNTLVIVLFMGRVN
                     KLTKNWSRSSGISIGIILQGLGFMIAFLGRDLTWELIAALIATIGEMILVPFSQALRAD
                     LMDGDQVGTYTGAFSVTQPIASVLSGILVSLSSLYGNIGMTIFMFFIIVLGVLPSLRAI
                     RMHESHS"
     misc_feature    7768..7781
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 24.19"
                     /tool="antismash"
     gene            7781..8320
                     /gene="rsmD"
                     /locus_tag="PGT72_RS11310"
     CDS             7781..8320
                     /EC_number="2.1.1.171"
                     /GO_function="GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /GO_process="GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /gene="rsmD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015427191.1"
                     /locus_tag="PGT72_RS11310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="WP_050558566.1"
                     /transl_table=11
                     /translation="MRVVSGNYGGRPLKTLAGKTTRPTTDKVKGAIFNMIGPYFEGGRV
                     LDLFAGSGSLAIEAISRGMDHAILVEKDRAAQQVILENIKMTKEPEKFQLLKMSAERVL
                     SNLSETFDLVLLDPPYSKEQIVENLELLQEKKRLTENVIVVCETDKEVELPDQIGKLEL
                     TRQKTYGISKISIYEF"
     gene            8368..8865
                     /gene="coaD"
                     /locus_tag="PGT72_RS11315"
     CDS             8368..8865
                     /EC_number="2.7.7.3"
                     /GO_function="GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="coaD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010906348.1"
                     /locus_tag="PGT72_RS11315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="WP_010906348.1"
                     /sec_met_domain="CTP_transf_like (E-value: 4.9e-21,
                     bitscore: 66.6, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEKIGLFTGTFDPLTNGHLDVIKRASQHFDQLYVGIFKNDQKNP
                     LFPTDKRVEMLEEALTSLSVTHKVKVIKHERDLTVNIAKKLGVTALVRSLRNSQDLEYE
                     KNMFYFNMEMTGIETIFFLAKPELEPLNSTRMRELHAFGQDVSAWVPENVSRELRKLDE
                     KK"
     gene            8852..9880
                     /locus_tag="PGT72_RS11320"
     CDS             8852..9880
                     /EC_number="3.4.21.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015427190.1"
                     /locus_tag="PGT72_RS11320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SepM family pheromone-processing serine protease"
                     /protein_id="WP_017865178.1"
                     /transl_table=11
                     /translation="MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLG
                     KMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSHFNSFTSIYSEQEMTGGLNDAQFNR
                     VNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAVNGQ
                     QFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEV
                     VTTPKVTVNAGSIGGPSAGMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGV
                     DKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAKKLKTKMKIVPVKNIQDALDYL
                     EK"
     gene            10001..10858
                     /locus_tag="PGT72_RS11325"
     CDS             10001..10858
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: TIGR01716"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017865177.1"
                     /locus_tag="PGT72_RS11325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="WP_017865177.1"
                     /sec_met_domain="TIGR01716 (E-value: 4.6e-32, bitscore:
                     102.5, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKNLKTGKIIAFIRETKHLKLKEMTGGSFSESQLAKFEKGETEI
                     TVGKLFTVLENSNVYLDEFQNLYNDYEQSDEYNFRHKLAVAYAQKNIDKIIEIHNFWKE
                     KSQQNPENKYYKINETVVKTNLVMVQNAEDIKKDTDLLMNYLESVSEWGRYELWVFGNC
                     LRHFDDNALKYYGMQILGKSNYYHSIHLNQQIVIRTFLNLIDTWLRRENLIQAFKYINH
                     LKEIGISINFFYEKILFEYHKAHYKVLQKQNGAIEEMKKHAQTLADYGFPLEAKGLFEE
                     IEKL"
     gene            10961..11887
                     /locus_tag="PGT72_RS11330"
     CDS             10961..11887
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF015983.4"
                     /locus_tag="PGT72_RS11330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="radical SAM protein"
                     /protein_id="WP_270343033.1"
                     /sec_met_domain="PTHR43273 (E-value: 2e-37, bitscore:
                     120.1, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 6.3e-10, bitscore: 30.6,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.2e-22, bitscore: 71.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 1.5e-07, bitscore: 22.2,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINYLKNPLFLTWMLTNKCNLRCKFCYLEDYQGKELELDEINQVL
                     DIIQDKEFTHVSLLGGEPTECEYFEYIIIQLEKLRISYSFSTNGQKLFRNEELIRILSK
                     SKYLKEVLISLESPQKLINDAVRGKGTFESAIKSVALLVKENVPTRLAMVVTKENNSTI
                     QQMIDMCATLGCRELRLMPFMPMGTGLLEKERLFMDYEGLVRACSDLKIPDNLIVTTYL
                     KEENTAETLGCGAGTAACVINSDLTLSACPVVSQTQKSIEKLGNDCSSFDYIWGTSSIF
                     NIWRAGKYRKSTSCNLCPLFEECGGYQ"
     gene            11884..13083
                     /locus_tag="PGT72_RS11335"
     CDS             11884..13083
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PGT72_RS11335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_270343035.1"
                     /transl_table=11
                     /translation="MTQFFNGQKILFINRILFDDAFITFVEVIFFSVYLKLSFSDFSSI
                     MGLCLLISLLVQIPTGYLSDKFDRKLMLVLGNGAEIVCLITLLFLPSLIKGSLFIPVLI
                     IEIIRTGMLALASGNFEVLIFNMFKREGKTEKDFMEKSASYFSIGAIIAAISGFVSTVL
                     FSYLVILPLILDLSIKIIKLLSAIFMCSEARHKEMTKIKMKVKSLNHKLLFLLFSLALL
                     FCISRGTFSLYQPVMTSLGIPLYYYGLLIMIVNLSIFVLLRVLKKKVSLFKLSTLLLVS
                     FAVLTFQGVLVIEHFIPGNLFRFLIVAIIFSSMQIIRLFSEGLSSYFINTAIKDRDDKT
                     TIFSLYSTMAQLLLSASFFLMGVVQGGVDNYLMTYLYISAIFVLIIMALGIFGKGQKYV
                     "
     gene            13076..13903
                     /locus_tag="PGT72_RS11340"
     CDS             13076..13903
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015427187.1"
                     /locus_tag="PGT72_RS11340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="radical SAM protein"
                     /protein_id="WP_026138971.1"
                     /sec_met_domain="Fer4_12 (E-value: 2.6e-12, bitscore: 38.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 3.7e-18, bitscore: 57.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 1.1e-09, bitscore: 29.2,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFRDDELFLPIKVYIYLTNHCHYECDYCFLKEMKMLNTKEISKED
                     LEKIAYYLEKYKVPLVAICGGDPILHPKLIDFVQLLSEHKNYPTIATNAVDVSYEYLYQ
                     LKSAGIRYLQIGIDSLRYSKLDNYKENGHLRKVEKTVKYLKELGILYGFATCVTRKNIG
                     ELSKIASYAKETGAELLKLSTYDGENQVYKLTEIQKEELKIFVRQYNTDGIYVRYSPVQ
                     ETLNYVSEYPSLTIYANGDLAIEETGDVIGNISTSEPAVEYKKYILEKWRTNK"
     gene            13900..14109
                     /locus_tag="PGT72_RS11345"
     CDS             13900..14109
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011677212.1"
                     /locus_tag="PGT72_RS11345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_003132661.1"
                     /transl_table=11
                     /translation="MKYKLNPLFTLRKTDKAVFNFSRAELTQFNDTGFDILLAVLEQES
                     DREWTDDEDEFLKELIKEKIVEES"
     gene            14096..14593
                     /locus_tag="PGT72_RS11350"
     CDS             14096..14593
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012898640.1"
                     /locus_tag="PGT72_RS11350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nitroreductase family protein"
                     /protein_id="WP_003132662.1"
                     /sec_met_domain="PF00881 (E-value: 4.9e-10, bitscore: 30.9,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNLEELIQLRKSNKFHNIGVNVESVIEVVKKSYYNFEKHSVPSA
                     GAIYGLKVLLFYKNNKKIFNSKGEISTEKFEINQIKKTCFYDDKYFSSSSILIAVAYDY
                     DKYFGKYGNCGIRYASIECGAFLQNFQLLLSEKEIYGCPLGFVDNDALLGIEEPLIYFI
                     IN"
     gene            complement(14931..17642)
                     /gene="adhE"
                     /gene_synonym="adhC"
                     /locus_tag="PGT72_RS11355"
     CDS             complement(14931..17642)
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /GO_function="GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA]"
                     /GO_function="GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006066 - alcohol metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="adhE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="adhC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003132664.1"
                     /locus_tag="PGT72_RS11355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="WP_270343037.1"
                     /sec_met_domain="Aldedh (E-value: 6.3e-20, bitscore: 62.2,
                     seeds: 89, tool: rule-based-clusters)"
                     /sec_met_domain="Fe-ADH (E-value: 7.4e-109, bitscore:
                     354.9, seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATKKAAPSAKKVLSAEEKAAKFQEAVAYTDKLVKKAQAAVLKFE
                     GYTQTQVDTIVAAMALAASKHSLELAHEAVNETGRGVVEDKDTKNHFASESVYNAIKND
                     KTVGVISENKVAGSVEIASPLGVLAGIVPTTNPTSTAIFKSLLTAKTRNAIVFAFHPQA
                     QKCSSHAAKIVYDAAIEAGAPEDFIQWIEVPSLDMTTALIQNRGLATILATGGPGMVNA
                     ALKSGNPSLGVGAGNGAVYVDATANIERAVEDLLLSKRFDNGMICATENSAVIDASVYD
                     EFIAKMQEQGAYMVPKKDYKAIESFVFVERAGEGFGVTGPVAGRSGQWIAEQAGVKVPK
                     DKDVLLFELDKKNIGEALSSEKLSPLLSIYKAETREEGIEIVRSLLAYQGAGHNAAIQI
                     GAMDDPFVKEYGEKVEASRILVNQPDSIGGVGDIYTDAMRPSLTLGTGSWGKNSLSHNL
                     STYDLLNVKTVAKRRNRPQWVRLPKEIYYEKNAISYLQELPHVHKAFIVADPGMVKFGF
                     VDKVLEQLAIRPTQVETSIYGSVQPDPTLSEAIAIARQMKQFEPDTVICLGGGSALDAG
                     KIGRLIYEYDARGEADLSDDASLKELFQELAQKFVDIRKRIIKFYHPHKAQMVAIPTTS
                     GTGSEVTPFAVITDDETHVKYPLADYQLTPQVAIVDPEFVMTVPKRTVSWSGIDAMSHA
                     LESYVSVMSSDYTKPISLQAIKLIFENLTESYHYDPAHPTKEGQKARENMHNAATLAGM
                     AFANAFLGINHSLAHKIGGEFGLPHGLAIAIAMPHVIKFNAVTGNVKRTPYPRYETYRA
                     QEDYAEISRFMGFAGKDDSDEKAVQALVAELKKLTDSIDINITLSGNGVDKAHLERELD
                     KLADLVYDDQCTPANPRQPRIDEIKQLLLDQY"
     misc_feature    17660..17675
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     misc_feature    complement(17727..17742)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.06"
                     /tool="antismash"
     misc_feature    complement(17813..17831)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 23.9"
                     /tool="antismash"
     gene            complement(17874..18899)
                     /locus_tag="PGT72_RS11360"
     CDS             complement(17874..18899)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017865172.1"
                     /locus_tag="PGT72_RS11360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lactonase family protein"
                     /protein_id="WP_017865172.1"
                     /transl_table=11
                     /translation="MKEKILLGGYTKRVSKGVYSVLLDTKAAELSSLNEVAAIQNPTYI
                     TLDEKGHLYTCAADSNGGGIAAFDFDGETATHLGNVTTTGAPLCYVAVDEARQLVYGAN
                     YHLGEVRVYKIQANGSLRLTDTVKHTGSGPRPEQSSSHVHYSDLTPDGRLVTCDLGTDE
                     VTVYDVIGEGKLNIATIYRAEKGMGARHITFHPNGKIAYLVGELNSTIEVLSYNEEKGR
                     FARLQTIGTLPEDYHGANGVAAIRISSDGKFLYTSNRGHDSLTTYKVSPLGTKLETIGW
                     TNTEGHIPRDFNFNKTEDYIIVAHQESDNLSLFLRDKKTGTLTLEQKDFYAPEITCVLP
                     L"
     gene            19257..20024
                     /gene="rpsB"
                     /locus_tag="PGT72_RS11365"
     CDS             19257..20024
                     /GO_component="GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA]"
                     /GO_component="GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /function="Ribosomal protein S2"
                     /gene="rpsB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010906340.1"
                     /locus_tag="PGT72_RS11365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="30S ribosomal protein S2"
                     /protein_id="WP_011836067.1"
                     /transl_table=11
                     /translation="MSVISMKQLLEAGVHFGHQTRRWNPKMKPYIFTERNGIHVIDLQK
                     TVKLVDDAYNYVKNASQEGAVVLFVGTKKQAAEAVKEEALRAGQYYVNHRWLGGMLTNW
                     NTIQTRVTRLKEINKMEEEGTFEVLPKKEVVLLNKERERLEKFIGGIADMPRIPDVMYI
                     VDPHAEQIAVKEAKTLGIPVVAMVDTNADPEPIDVVIPANDDAIRAVKLITAKMADAII
                     EGRQGEDAAEDFVAEEAASEESLEELAEIVEGK"
     misc_feature    20086..20099
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.27"
                     /tool="antismash"
     gene            20144..21172
                     /gene="tsf"
                     /locus_tag="PGT72_RS11370"
     CDS             20144..21172
                     /GO_function="GO:0003746 - translation elongation factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="tsf"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010906339.1"
                     /locus_tag="PGT72_RS11370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="translation elongation factor Ts"
                     /protein_id="WP_058224272.1"
                     /transl_table=11
                     /translation="MAVTAAQVKELREKTGAGIMDAKRALVETDGNMEAAAELLREKGI
                     AKAAKKADRVAAEGLTGIAVNGNVAAIVELNSETDFVAKNDQFVALVKEIAELIASKKP
                     ATNEEALALETASGITLEAELVQATATIGEKITFRRFAVIEKTDAQHFGAYQHNGGKIG
                     VVSVVEGADETLAKQLSMHIAAMNPTVLSADELDSEFVKAELAQMNHKIDEDNASRVLV
                     NKPELPHHEFGSKSQLTEEVLAAAKASFEEELKAEGKPEKIWDKILPGKMAKFIVDNTK
                     VDQQFALLAQLYIMDDSKTVEAFLESKGAKAIAFTRFEVGEGIEKAETDFAAEVEAAKA
                     GL"
     gene            21377..23107
                     /gene="ezrA"
                     /locus_tag="PGT72_RS11375"
     CDS             21377..23107
                     /codon_start=1
                     /gene="ezrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003132670.1"
                     /locus_tag="PGT72_RS11375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="septation ring formation regulator EzrA"
                     /protein_id="WP_017865171.1"
                     /transl_table=11
                     /translation="MSSTVIILIVVLLVIIVAFYAFAILMRKKTEDRILALEERKESLF
                     DLPVQEEIDSVKKMHLVGQSQTIFREWNQKWLDLSSNSFADLEEHIFEAEQLNDSFHFF
                     RARESVADSEAQIELMEGDVEGIRQGVAQLVEQEKRNSNKIQESLDLYDNLRSDIADNA
                     DLYGTVITELEKHLANIETEFSQFVTLNSTGDPIEAAEVLETAEEHTIALRAITEQIPS
                     FIKTIEKDVPKRLEELQEASDKFVAEEYILPDNVNIKERMDDLHDHLVESSSLLEQFEL
                     DRVEAELGLIQEKVEELYAIFEREYSARRNVEKRSSVLKEYIEHIRANNKNLLLEIDHV
                     TQAYILSGNEKGYVRGYQEHLESLDSDVDEILGNIQAKTMPYSILSRRVNSVVNALEDI
                     EKNQIKISDTLTGLRDEERAAQEIAERFDSELRTIKRYVEKCNLPGLPKDYLDLFFTTG
                     DRVQNLFKELGRVRINIDTINHLVDVSTEDMHVLKEATTNLTDHAVLAEQLIQYANRYK
                     AANEQVAQGISRALQLFENSRDYDGSFDEISKTLELVEPGAASRISGVYFKNKPTPDYL
                     "
     gene            23366..23857
                     /locus_tag="PGT72_RS11380"
     CDS             23366..23857
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017865170.1"
                     /locus_tag="PGT72_RS11380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_270343042.1"
                     /transl_table=11
                     /translation="MTYYLEEEDFENLFSEMKPIVMKLMKQIRIRTWKIEDYLQEGMII
                     LHLLLEEQSDGQKLHTKFKVKYHQRLIDELRRSYAKKRSHDHFIGLDVYECSDWINSGD
                     TSPDNEVVFNHLLAEVYEGLSAHYQELLLRQMRGEELTRMERYRLREKIKAILFSEDEE
                     "
ORIGIN
        1 tacatagtga tagtacaatg atattataca cttaggtagt caaaaaagca agctacttta
       61 aaatataaaa aataataaat aaatggagga tttaacatga aatatttagt aacaggtgcg
      121 acaggtggat atggtactta tgcactcgga tttttgaaag aattggttcc aatttctgat
      181 attgcggttt tggctcgcac agaagaaaaa gcagccccac tcaaagcggc aggtttcgat
      241 gtacgtttgg cagattattc agatttaact gctttagaac aagcatttac aggaattgat
      301 cgtttgcttt ttgtttcagg agcgccggga aatcgtcaag ctgagcatca aaatgttgtt
      361 gatgcagcca aaagtgctgg aatttcttat attgcttata caagttttcc tcaagcagaa
      421 agggcaacaa gtgacttagc tgctgaccac atctatactg aaaaggcgat taaaaaatca
      481 ggaattgctc acacattttt acgtaataac tggtactttg aaaatgaaat gccaattatt
      541 gctgccgcac tttcaactgg aaaatttgtt tacaatgcac caacaggtaa agtgggctgg
      601 gctttgaaac gtgaatatgc agaagttgga gcaaaagcac ttgctggagc agattttcca
      661 gaagttttgg agctttcagg aaaaatattg acttacgccg aacttgctca agcactaaaa
      721 gcagtttctg ataaggaatt tgaagtagtc gctgctgatg acaaaacttt tgtcagtcat
      781 ttagttgaaa ctggacttcc agattttgta gcggaacttt tcctcggctt ccaaaaagat
      841 attgaagcaa aagatttaga tgtggaatct aaagattttg aaaaagtctt gggacattca
      901 ctgacagata caaaagaagc tttgaaagaa cttttggcat aataaaaaaa ttactgacag
      961 gtctgtcagt aatttttatt tgagtctata agataatttc tcaacaaatt cataagcagc
     1021 tggacagtaa agtgtatttt ttatcgttaa attattgatt tgataaatct ttttacggtc
     1081 agtatgggga aattcgcgac aagctttagg ccgaacttcg taaatgctac agagattgtc
     1141 agaaccaaga aactgacaag gcatggtttg aaaaactttg tcaccatctt cgtcagttcg
     1201 gagatatgcg gcttcaaagt cactcacttt catttttaaa tgtttggcga cgcgttcaat
     1261 atcggcctct gtccaaagag gacctaaggt tttgcaacaa ttagcacatt tggtgcaatc
     1321 aatttctaaa aaaacctctt catgaacttc tttaacgatt ttatctaatt gctttggtgg
     1381 ttttttggca agtccagcta aaaatttctt atgtgtcttt tgtttttgtt gggctagatt
     1441 tttataacgg tcaaggtcaa tttcaaatgt atatttcatc attaatattt tagcaaaaat
     1501 ttacatgaaa gactgatttg tcagtcgtca aagagatttg acacacttaa aagtgttagg
     1561 acttatctta tcagtaaatc ttttaataac aataaatatt cattgaaatc ttaaactaaa
     1621 tttttataaa aaaagctgtc ccaaagctgg aaaagtttca cagatagaaa gctaaacaaa
     1681 taagcgctta cataaccttt agtattgtta aaaagccgaa aaagtgataa aatgaactag
     1741 aaaattcgaa gataaaacaa tgcaaaagtt gtcgttcttc aatagctaaa ttctcgtaaa
     1801 aagcgagaaa ttgaaaggaa ttaaaatggc tcatattaaa tttgactatt caaaactcac
     1861 tccatttgta gctgaaaatg aattagacga aatccaatgg caaatcgacg gggcagctaa
     1921 attgctccac gaaggaaaag gtgctgggag cgattatatc ggatggcttg accttcctga
     1981 agattacgac aaagaagaat ttgctcgtat tcaaaaagca gctaaaaaaa ttcaatctga
     2041 ttcagaagtt cttattgtta tcggtatcgg tggttcatac ctcggtgcac gtgcagcaat
     2101 tgactttttg agcaacagct ttgttaactt gcaaactgcc gaagaacgta aagcaccacg
     2161 tattctttat gctggtaact caatttcttc atcatacttg gctgaccttg tagattacgt
     2221 tgctgacaaa gatttctctg taaatgtaat ctctaaatca ggtacaacaa cagaaccagc
     2281 gattgctttc cgtgtcttcg aagaaatgtt agttaaaaaa tacggtcgtg aagaagcaaa
     2341 caaacgtatt tacgcaacaa ctgataaaga aaaaggtgct gtaaaagtta atgctgacgc
     2401 aaacaactgg gaaacttttg ttgttccaga ttcagttggt ggacgcttct cagtattgac
     2461 agctgttgga cttttgccaa ttgcagcttc aggtgctgat atcacagctt tgatggaagg
     2521 tgctaacgct gcgcgtaaag aatacacttc tacaaatgtt catgaaaatg atgcttacgc
     2581 ctatgctgca cttcgcaata tcctttaccg taaaggtaaa ttctcagaaa tcttgatcaa
     2641 ttacgaacca agccttcagt atttctcaga atggtggaaa caattggctg gtgaatcaga
     2701 agggaaagac caaaaaggaa tttacccaac ttcagctaac ttctcaacag accttcactc
     2761 attaggacaa tggattcaag aaggaacacg tactgttttt gaaacagcta tccgtattga
     2821 aaaaccacgt aaaaacatca acattccaga acttgacgct gaccttgatg gacttggata
     2881 cttgcaaggt aaagatgttg acttcgttaa caaaaaagca gctgacggcg tgcttcttgc
     2941 tcacactgac ggaaatgttc caaacatgat cgtgacattg cctgaacaag acgaattcac
     3001 acttggatat gcaatttact tctttgaact tgctatcggt gtttctggtt acttgaacgg
     3061 aattaaccca ttcaaccaac caggtgttga agcttacaag aaaaatatgt tcgctcttct
     3121 tggtaaacca ggatttgaag aactcagcaa agaattgaat gaccgccttt aatctttgat
     3181 taaaagtgtc ataaaaatca ctgacaagat ttctgtcagt gattttttgt attcatttct
     3241 tactgataaa tcctgtcagt aaaattatta tttaagtggc ttaatatcag ggcgaagttc
     3301 tactgtgagg ccaacattac ttgcataaac ccaagaattt ttatcaaaat tcgcaaaatt
     3361 cttagtttgt cctgttaaaa tgacccccga aaatttagct gatttaagag taggatattt
     3421 tttaacttgt ttaagtgcgt ctttacttgg gctaaagtcg ttaattgtga tttggttctt
     3481 tttcgcaata gcagctactg actttttaaa atcttgataa gtagtattgt ctaattttcc
     3541 agtgagtttt gaattattac cattttcagc ataattgcta ttactcatta agccaaacca
     3601 gtttgtttgt ccagcagcat caagagattt cgaatcattg taaccaatcc aataccaatt
     3661 aattaaaaga ttttcgggaa tcattttttg gatttcgttg taactataag ctttatcaaa
     3721 ggtgacagca acttccgcca cgtggtttga aagttgtgaa attttgtctg catcatgggt
     3781 aggcagaatt ccattataat ctttagattt gtagttggca tttgtagaga aaaaactagc
     3841 aattttttga ttagttgttt gggtaaaata ggcatttgaa tttactgacg gactcaaggt
     3901 attaagactt aagcccccaa catttgaaac attaaaggaa aaattataag attcccaggg
     3961 cacatgataa ccatcaatat ctttataagt atctgaatga agattagaac taaacacgcc
     4021 ataatcatcg ataatctgat tattataagc aatatttggg gcggaagcgg tgaaaatagc
     4081 ggtagagtaa tcaaaagttt taaagaaatt tttttccatg atagcagagt tcactcgcca
     4141 accaacaact ataaatgctg aaaatacagt caaagcaatc caagtagtta acccccaacg
     4201 ttttattttt gtttttaggg caaaattatg aaaatctttg ttgagattag aaatagattc
     4261 agttttttga agtttatgtc gtgttttatt gattacaaaa ataaacagac gaatcagtcc
     4321 gaaaaataaa gtgatggcta aaacaaggta agggaaaatt aagagagtat gcatttttaa
     4381 atcctttcat gagacgatta gaggagccac tggtcataac cagctttttc aagttgtttt
     4441 ttaagctttt ttcgagctcg ataaaggtcg attttgattt tgcttaaact acattcaaaa
     4501 tattctgcaa gctgtttagt tgaacaattt tcataatagt atgcatttaa aagctcttta
     4561 taataaggtg gaagttgttc aatgattttt ggaagtgggc tagactcaac taaaaaagct
     4621 gctgtttcca attctttttc caaattttta ataatttttt gataatgttt actccgatta
     4681 taactattaa tataagttcg gatagatgtt cgatacataa aagcccgtaa tttgtcaggt
     4741 tcaatgaaaa tatccagact taaaatttta accagagtat cctgtacggc atcttcggca
     4801 tcgaccaact gacttccccg agagataagg tatttagtga tttctatcgc ataatcattg
     4861 acgtcatttt catattcttt taaattcacc atttcctcct ctctcatata tataacaaat
     4921 caaattaagt ttggttacag tttattttaa caaaaattga tataagtaga agaattattt
     4981 tgataaagct gtaattcatc tagttttaga agtataaata tgctacaatt atagataaat
     5041 taataaattt agaaaattta aaagaattta aggaataata tgaaagagtt ttggaattta
     5101 gacaaaaatt tgcaactccg tttaggaatt gtttttttag gtgccttttc atatggcacc
     5161 gttttttctt caatgaccat ttattataat caacatttgg gaagtgcaat tacagggatt
     5221 ttgcttgcct tatctgcagt agccactttt gtcgcaggga ttcttgcagg cttttttgct
     5281 gaccgaaatg gtcgaaagcc agtgatggtt tttgggacag tgattcaact tttgggagct
     5341 cttttagcca ttgcctcaaa cttaccaggt cacgtgaatc cttggtcgac ttttattgct
     5401 tttttgctga ttagttttgg ttataatctt gtgattactg caggaaatgc catgattatt
     5461 gatgcatcaa atgctgaaaa tcgtaaagtt gtttttatgt tggattattg ggcgcaaaac
     5521 ttgtcagtta ttttaggagc agcattaggt gcttggcttt ttagaccagc atttgaagca
     5581 cttttagtga tattactttt aactgtctta gtctcatttt tcttaaccac ttttgtaatg
     5641 actgagactt ttagaccgat tgtaaaggcc aaagaagaag cagaaaatat ttttcaggcc
     5701 tataagacag tgctacaaga taaaacttac atgattttta tgggtgctaa tattgcgacc
     5761 acttttatta tcatgcaatt tgataatttt ttgcctgttc atttatcaaa tagttttaaa
     5821 acaatcactt tttttggttt tgaaatctat ggacaacgga tgcttacgat ttatttgatt
     5881 ttagcttgtg tattagtcgt cctattaatg accaccctaa atcgattgac caaggactgg
     5941 tcacaccaaa aaggatttat ttggggaagt ttatttatgg caattgggat gattttttca
     6001 tttttgacaa cgacgtttac gcctattttc attgccggta ttgtttatac tttaggtgaa
     6061 attgtttata caccaagtgt tcaaacttta ggtgcagatt tgatgaatcc agaaaaaatt
     6121 ggttcttaca atggcgttgc cgcaattaag atgccgattg cctccattct tgccggttta
     6181 cttgtttcga tttcaccaat gattaaagca acaggagttt ctttagtctt agcattaact
     6241 gaagttctag cgattatttt agtgcttatt gctgtaaata gacaccagaa aacaaaaatt
     6301 aattaaaaaa atgacctcta aaaaaaagaa tttatcttga aaaggagtca aggtaggttt
     6361 tttattgaaa aaaaacagaa agaaataaaa tgaaagattt ttttggatta catccaacac
     6421 ttaaaattcg tttaatcatg aatttttttg ggacgctttg ctttagtaca gtgggtggct
     6481 caatgacaat ttactacaat aaatatatgg gagcgggaat cacgggatta cttttagtca
     6541 ttagttcagt catggttttc ttggttgggc tttatgctgg tcatttgtcc gacgttcagg
     6601 gacgaagacc tgtgatgatt ttctcaactg ccattactgg ttttggtgga gctttagcaa
     6661 catttgcaaa ctcatctttt tacttcaatc cttgggtcac ttttttagga tttcttatta
     6721 ttaattttgg ttttggcttt tttaacaccg caagtcaagc gatgattgta gatttgacaa
     6781 caagtggaaa tcggcgagtc gtttatagta ttcaatattg gattatcaat tttgcaatca
     6841 tgattggttc aggactttca ggttggtttt tccgagatta tttggtttgg ttacttttag
     6901 ctatcacaat tgaagaaatc gttagttgtt tggttgtaat tttttggatt gatgaatcct
     6961 tcaatccaga tactcagcag cataagcaag aatcaaacat tattaaagcc tatttcacag
     7021 ttgctaaaga ccgtattttc atgtattatt tatttgcttc ggtctttatt gcgatgattt
     7081 ttaatcaaat tgattattat cttccagtcc atttgagtga tagttttaga acagcaagga
     7141 tttttggaat tgaagtttat ggacaacgga tgctgacaat tttcctaatg gtcaatacct
     7201 tagtcatcgt attatttatg gggagagtca acaaactaac caaaaactgg tcacgaagta
     7261 gtggaatatc cattggaatt attttgcaag gtttgggctt catgattgca tttcttggtc
     7321 gtgatttaac ttgggaactg attgcagcat tgatagcaac aatcggtgaa atgattttgg
     7381 ttccattttc acaggctctg cgagccgatt taatggatgg agaccaagtg ggaacttata
     7441 caggagcttt ttcagtgact cagcctatcg cttcggtctt gtcaggaatc cttgtgtctc
     7501 tctcaagtct ttatggaaat attggaatga ccatcttcat gtttttcatt attgtattag
     7561 gtgtgctgcc ctcactacga gcaattcgga tgcatgaaag tcattcatga gttaaatata
     7621 ggtaaaaata agtttcaaaa gttagaatga aattctgatt tgagaaactt atttttttgt
     7681 cagtaaaata ataagaaaat ttttactgac agaaccttta gaccaaggct tacagggaga
     7741 ttcggctctc catttgaaat tttgtgatat aattattttc atgagagtag tatcaggaaa
     7801 ttatggcgga agaccgctga aaacattggc aggaaaaaca acaagaccaa ccaccgataa
     7861 agttaaagga gccattttta atatgattgg cccttatttt gaagggggac gtgttcttga
     7921 tttatttgca ggctcaggca gtttggcaat tgaagccatt tcaagaggaa tggatcacgc
     7981 cattctcgtc gaaaaagaca gagcagctca acaagtcatt ttggaaaata tcaagatgac
     8041 caaagagcct gaaaaatttc aattattaaa aatgtcagca gaacgagtct tatcaaactt
     8101 gtcagagact tttgatttag tcctcttaga cccaccttat tctaaagaac aaattgttga
     8161 aaacttagaa cttttgcaag agaaaaaacg actgacagaa aatgtaattg tcgtctgtga
     8221 aacagacaag gaagttgaac tccctgacca aattgggaaa ttagagctga ccagacaaaa
     8281 aacttacgga atttctaaaa tttcaattta tgaattttga cttttactga cagaaattct
     8341 gtcagtaaat taagaaagaa aaaagtaatg acagaaaaaa ttggactctt tacaggaact
     8401 tttgacccac tgacaaatgg tcatttagac gttatcaaac gtgccagtca acattttgat
     8461 caactttatg ttggaatttt taaaaatgac caaaaaaatc cactttttcc aactgataaa
     8521 cgagtggaaa tgctagaaga agcactgaca agcctgtcag taactcataa agtcaaagtc
     8581 atcaaacatg aacgtgattt gacagtgaat attgctaaaa aacttggcgt gacagctctg
     8641 gttcgttctt tgcgtaatag ccaagattta gaatatgaaa aaaatatgtt ctattttaat
     8701 atggaaatga caggcattga aaccatcttt ttcttagcaa aaccagaact tgaaccatta
     8761 aattcaacac ggatgcgaga attacatgcc tttggtcaag atgtcagtgc ttgggttcca
     8821 gaaaatgtga gtcgtgaatt aaggaaatta gatgaaaaaa aataaaaaaa ttaatcccaa
     8881 attaaaatgg ggaatctcga ttggtctaat tgttgttgcc cttttagctt tattttatcc
     8941 aacgagttac tatgtggaaa tgcccggaac aaccgagcct ttagggaaaa tggtcaaagt
     9001 tgaaggcaaa aaagatgaac ataaaggtga ttttttcctg acgactgtcc aaattgcacg
     9061 agcaaatctt gctacaatga tttacagcca ttttaatagt tttacaagca tttacagtga
     9121 gcaagaaatg actggtggac ttaacgacgc acagttcaac cgtgtcaacc agttttacat
     9181 ggaaacggca cagaatacag cgatttatca agcttttaaa ttagctaata aaccttatga
     9241 acttaaatat gaaggcgttt atgtccttga tattgccaaa aattcgacct ttaaaaataa
     9301 gctagaactt gcagatacga ttacagcagt caatggtcaa cagtttacat caagtgccga
     9361 catgattgct tatgtttcca aacaaaaagt cggtgattca gtaacgattg aatacacgag
     9421 aattgacggc acaaagcaca agtcaactgg caaatacatc aaaattgcta atggaaaaac
     9481 aggaattggg atcagcctag ttgaccatac tgaagtcgtg acgactccaa aagttactgt
     9541 caacgcgggt tcaatcggtg gtccctctgc ggggatgatg tttacactag aaatttacag
     9601 tcagttgaca ggaaaagatt tgcgaaacgg tcgcgaaatt gctggaactg gaacgattga
     9661 acatgacgga agcattggcc aaatcggcgg tgttgataaa aaagtagcca cagcgagcaa
     9721 agaaggggca aaggtcttct tagtgcctga ctcaggcacc aaaaaggaaa gtagcaacaa
     9781 ttaccttgga gccaaagccg cagctaaaaa actaaaaacg aagatgaaaa tcgttcccgt
     9841 caaaaatatt caggacgctt tagattattt agaaaaataa aaactactga cagcttttct
     9901 gtcagtagtt ttttcatcta gtttacaagc taaaagcaaa gttgtataat aatttcaaat
     9961 aatttaataa atttggaata tatgacaaag ggaaaatgaa atggaaaaaa atttaaaaac
    10021 cggaaaaatc attgctttta tcagagaaac gaagcatcta aaattaaaag aaatgactgg
    10081 tggttctttt tcagaatctc agctcgcaaa atttgaaaaa ggagaaacag agattacggt
    10141 gggtaaacta tttaccgtcc tagaaaattc aaatgtctat ttagacgaat ttcaaaatct
    10201 ttataacgac tatgaacaat cagatgaata caactttcgt cacaagttgg cggttgctta
    10261 tgcgcaaaaa aacatcgata aaatcataga aattcataat ttttggaaag aaaaatctca
    10321 acaaaatcct gaaaataaat actataaaat taatgaaaca gtagttaaaa ccaacttagt
    10381 aatggttcaa aatgcagagg atatcaaaaa agatactgac cttttgatga actaccttga
    10441 atctgtcagc gaatggggac gctatgaact gtgggttttt ggcaattgtc ttcgacattt
    10501 tgatgataat gcactaaagt attacggaat gcaaatttta ggaaaatcaa attattatca
    10561 ttcaattcat ctcaatcaac agatcgtaat aagaacattt ttaaatctca ttgatacttg
    10621 gttacgtcga gaaaacttaa tacaagcttt taaatatatc aaccatttaa aagaaatagg
    10681 aataagtatc aattttttct atgaaaaaat tctctttgaa tatcacaaag ctcattataa
    10741 ggtattgcaa aaacaaaacg gagcgataga agaaatgaaa aaacacgcgc aaactcttgc
    10801 agattatggt ttcccactag aagcaaaggg cctttttgaa gaaattgaaa aattataggg
    10861 ctttggcata tattccaaaa gaaaatttcc acccaatttt atatgttaag atacagataa
    10921 taaaaattat ctgtattttt ttatagattg gagaagtaag atgattaatt acctaaaaaa
    10981 tccactgttc ctgacttgga tgcttaccaa caaatgtaat ttaaggtgta aattttgtta
    11041 tttggaagat tatcaaggaa aagagttgga gcttgatgaa ataaatcagg tcctagatat
    11101 tatacaagat aaagaattta cccatgtttc tctattgggc ggtgaaccga cagaatgtga
    11161 gtactttgaa tatattatta ttcaactaga aaaattgaga atttcatact cattttcaac
    11221 taatggtcaa aaactattta gaaatgaaga gttaattaga atactttcta aatccaaata
    11281 tttaaaagag gttctaattt ctttagagtc tccccaaaag ttaatcaatg acgcagtcag
    11341 agggaaagga acatttgaaa gtgcaataaa aagtgtagca ctattagtaa aagagaatgt
    11401 tcctacacgg cttgctatgg tcgtgacaaa agaaaataat tctaccattc aacaaatgat
    11461 tgatatgtgt gccacattag ggtgtagaga attgcgatta atgccattta tgcccatggg
    11521 aacgggatta ttagaaaaag aacgcctatt catggattat gaaggtttag ttcgagcatg
    11581 ctcagattta aaaataccag ataatctaat tgtcacaact tacctaaaag aagagaatac
    11641 cgctgaaact ttaggttgtg gtgctggaac agctgcctgc gttataaata gtgacttgac
    11701 actttcagcc tgtcctgtag tatctcaaac ccaaaaatct atcgaaaaat taggtaacga
    11761 ttgttcaagt tttgattaca tatggggaac aagttcgatt tttaatatat ggagagcggg
    11821 aaaatatcga aaatcaacct cgtgtaactt atgtccgcta tttgaggaat gtggggggta
    11881 ccaatgactc aatttttcaa tggtcagaaa attttattca taaatagaat actttttgat
    11941 gatgcattta taacgtttgt agaggttata tttttcagtg tgtatttaaa gctttctttt
    12001 tcagattttt caagtattat gggcttatgt ttgttaattt cgttgttagt tcagattcca
    12061 acaggttact tatccgataa gttcgatagg aaattaatgt tagtattagg aaatggtgcg
    12121 gaaattgtgt gtcttataac tttacttttt cttcctagtt tgataaaagg ctctttattt
    12181 attccagttt taattataga aattataaga acaggcatgt tggctttagc gagtggtaat
    12241 tttgaagtgt taatatttaa tatgtttaag agagaaggaa aaactgaaaa agattttatg
    12301 gagaaatccg cctcatattt ttccatagga gcgattatag cagcaatttc tggatttgtt
    12361 tccacggttc tattttccta tctagtgatt ttgccactta tattggattt atcgataaaa
    12421 atcatcaaat tattatctgc tattttcatg tgttctgaag cgagacataa agaaatgaca
    12481 aaaataaaaa tgaaagtaaa gtccttaaat cataaattgt tatttctctt gttctcgctt
    12541 gcccttttat tttgtatttc aagggggaca ttttctttat accaaccagt tatgacttca
    12601 ttaggtattc ctctttatta ttatggccta cttattatga tagtgaacct gtcgatattc
    12661 gttcttttga gagttttgaa aaagaaagta tcgctgttca aactttcaac attactcctt
    12721 gtttcttttg cggttcttac ttttcaagga gtattggtaa ttgaacattt tataccagga
    12781 aatctttttc gttttttgat tgtagcgata atattttcaa gtatgcagat tatcagacta
    12841 ttttcagaag gactctcctc ttattttatc aacaccgcga ttaaggatag agacgataaa
    12901 acaactattt tttctcttta ttctacaatg gcccagcttt tactatctgc ttctttcttc
    12961 ctgatgggtg ttgttcaagg gggagttgat aactatttga tgacctattt atatattagt
    13021 gcaatttttg tcctaattat tatggcttta ggtatctttg gaaaggggca aaaatatgtt
    13081 tagagatgac gaactttttt taccaattaa ggtgtatata tatttaacta atcattgtca
    13141 ttacgaatgt gattactgct tccttaaaga aatgaagatg ttaaatacaa aggagatctc
    13201 aaaagaagat ttagaaaaaa tagcttatta tttagaaaaa tataaagtac cattagttgc
    13261 tatttgtggg ggagatccaa ttctccaccc aaaacttatt gattttgtcc aattactatc
    13321 agaacataag aattatccaa ctatagcgac taatgcagtt gacgtatcct atgagtattt
    13381 atatcagtta aaatcagcag gaattcgata tttacagata ggcattgata gtttgcgata
    13441 ttcaaaattg gataattaca aagaaaacgg gcatcttaga aaagttgaaa aaactgtgaa
    13501 atatttaaaa gaattgggga tattatatgg ttttgcaact tgtgtcactc gaaaaaatat
    13561 tggagagctt agtaaaattg cgagttatgc taaagaaaca ggagccgaac tgttgaaact
    13621 ttcaacttat gatggagaaa atcaagtata taaattaaca gaaattcaaa aagaagagtt
    13681 aaaaatcttt gtaagacaat ataatactga tgggatttat gtacgctact cgcctgttca
    13741 agaaacatta aattatgtat cggaatatcc ctccctgaca atatatgcaa acggggattt
    13801 agcaattgaa gaaacaggag atgttattgg aaatatttcc acttctgaac cagctgtaga
    13861 atataaaaaa tatatattag aaaaatggag aacaaataaa tgaagtataa attaaaccca
    13921 ttatttacgc tcagaaaaac agataaagca gtcttcaatt tctcaagggc ggaattaaca
    13981 caattcaacg atacaggttt tgatatttta ttggcagttc ttgaacaaga aagtgataga
    14041 gagtggacag atgatgaaga tgaatttctg aaagagttaa tcaaggagaa aatcgttgaa
    14101 gaatcttgaa gagcttattc aactaagaaa atcaaataaa tttcataata ttggtgtaaa
    14161 tgttgaaagt gtaatagaag tagtaaaaaa atcctactat aattttgaga aacatagcgt
    14221 tccttctgcc ggagctatat atggtttgaa agttttactt ttttataaga acaataaaaa
    14281 aatatttaac tctaaagggg agataagtac agagaaattc gagataaatc aaattaaaaa
    14341 aacttgtttt tatgatgata aatatttttc ttcaagttca attcttattg ctgtggcata
    14401 tgattacgat aaatattttg gtaaatatgg taattgtggg ataaggtatg cttcaatcga
    14461 atgtggtgct tttctgcaaa attttcaact actactttca gaaaaagaga tatacggttg
    14521 tccattaggc ttcgtagata atgatgctct gttgggaata gaagaacccc taatttattt
    14581 tattattaat taatctttga taagatatcc gaagtttagg attcttatat aactatttgg
    14641 gctcaaaata gtaccataat aaggaagaat tttcttgaac aaagaaactg tgaaagatgt
    14701 tcgcaaagaa cataaagaaa aaccagaatt taaaacaatt tcattattag catgcatgaa
    14761 ctcgacttct atcgctaatt aattattgat ttttatagaa atataaatca atggagtgaa
    14821 aagagcctat atcgaaattg atttatacct tttgatagtt gtataagcta taataaaaaa
    14881 tgctctgacg aattcatcag agcgttttta ttatttttat caacagatta ttagtattga
    14941 tctaacaaca actgtttaat ctcatcaatt cttggttgac gaggattagc aggagtacat
    15001 tgatcatcat aaacaaggtc agccaattta tcaagttcac gttcaaggtg agctttatcg
    15061 acaccatttc ctgaaagggt gatattaata tcaatgctat cagtcagttt cttaagttca
    15121 gcaaccagag cttgcacagc tttttcatct gaatcatctt taccagcaaa tcccatgaag
    15181 cgtgaaattt cagcgtagtc ctcttgagca cgatatgttt cataacgtgg gtaaggggta
    15241 cgtttaacgt ttcctgttac agcgttaaat ttaatgacat gtggcatagc gatggcaatg
    15301 gcaagaccat gaggaagtcc aaattcacca ccaattttat gagcaagtga gtggttaatt
    15361 ccaaggaaag cattagcgaa ggccatacca gcgagtgttg cagcattgtg catattttcg
    15421 cgggcttttt gtccttcttt agttggatgc gctgggtcat aatgataaga ctcagtcaag
    15481 ttttcaaaga taagtttgat cgcttgaagt gaaattggtt ttgtatagtc agaagacata
    15541 acagaaacgt aagattcaag cgcgtgtgac atcgcatcaa taccagacca agaaacagta
    15601 cgttttggta cagtcataac aaactcaggg tcaacaatgg caacttgtgg tgttaattgg
    15661 tagtcagcaa gtgggtactt aacatgggtt tcatcatcag tgataactgc aaatggagtc
    15721 acttcagaac cagtaccaga agtagtagga attgcaacca tttgtgcttt atgtggatgg
    15781 tagaatttaa taatacgttt acgaatatcg acaaattttt gagctaattc ttggaaaagt
    15841 tctttcaaac ttgcatcatc agaaaggtca gcttcaccac gagcatcata ttcataaatc
    15901 aaacgaccaa tcttaccagc atcgagagca gaaccaccac caagacagat gacagtgtca
    15961 ggttcaaatt gtttcatttg acgagcgatt gcaattgctt cgctcaaagt tgggtcaggt
    16021 tgaacagagc cataaatgct tgtttcaact tgagttgggc ggatagcaag ttgttccaaa
    16081 actttatcaa cgaaaccaaa tttaaccata ccagggtcag caacgatgaa agctttgtga
    16141 acgtgtggca attcttgtaa gtaagaaatt gcattttttt cgtagtaaat ttcttttggc
    16201 aaacgaaccc attgtgggcg attacgacgt ttagccactg ttttaacatt caatagatcg
    16261 tatgtactca aattgtgtga aagtgaattt ttcccccatg aaccagttcc aagtgtaagt
    16321 gatggacgca ttgcatcagt atagatatct ccgaccccac caatagaatc tggttggtta
    16381 acgaggatac gagaagcttc aactttttcg ccatattctt taacgaatgg atcatccatt
    16441 gcaccgattt gaattgcagc attatgtcca gcaccttgat aagcaagtaa gctacgtaca
    16501 atctcaattc cttcttcacg tgtttcagct ttgtagattg aaagcaaagg agaaagtttt
    16561 tcagaagaaa gtgcttcacc aatatttttc ttatcaagtt caaaaagaag gacatcttta
    16621 tctttaggaa ctttgacacc agcttgttca gcaatccatt gaccagaacg accggcaaca
    16681 ggaccagtta ctccaaaacc ttcaccagca cgttcaacaa aaacgaaact ttcaatagct
    16741 ttgtagtctt ttttaggaac catataagcg ccttgttctt gcattttagc aataaattca
    16801 tcataaactg aagcatcaat aacagctgaa ttttcagtgg cacaaatcat cccattatca
    16861 aaacgttttg aaagcaaaag gtcttcaacg gcacgttcaa tatttgcagt tgcatcaaca
    16921 taaacagcac cattaccagc tccaacaccg agtgaagggt taccagattt gagtgcggcg
    16981 tttaccattc ctgggccacc agttgcaagg attgttgcaa gtccacggtt ttgaatcaag
    17041 gcggtagtca tgtcaagact tggtacttca atccattgaa taaagtcttc cggtgcacca
    17101 gcttcaattg cagcatcgta aacaattttt gctgcatggc ttgaacattt ttgagcttgt
    17161 gggtggaaag cgaaaacaat agcattacgt gtttttgcag tcaataaaga tttaaagatt
    17221 gctgttgatg ttggattagt cgttggaacg ataccagcaa gtacaccgag agggcttgcg
    17281 atttcaacag atccagcaac cttgttttca gaaatgacac caacggtttt gtcattttta
    17341 attgcgttat aaacagattc agaagcaaag tggtttttgg tatctttgtc ttcgacaaca
    17401 ccacgaccag tttcgttaac ggcttcatga gcgagttcta gagaatgttt gcttgctgca
    17461 agagccattg cagcgacaat agtatcgact tgagtttgtg tatatccttc aaatttaaga
    17521 acagcagctt gtgctttttt gactaatttg tcagtataag caacagcttc ttggaatttt
    17581 gcggcttttt cttcagcgct taaaactttc tttgcagatg gagcggcttt tttagttgcc
    17641 atatttgtag gttctccttt gtgatttcgt tcactttctt ttacgtgaat agtttaacaa
    17701 agttttttat agatgtcaag caatattgtg atagttttta caaaaacact catcaaaagt
    17761 ttagaaaacg gtttataaca agctttactg aagaaaaaaa gattgctaat tctttgagag
    17821 gaattagcaa tcttttttag tttatcagtc aaactttgtg aaaaaataaa tttttatagt
    17881 ggtaaaacac aagtgatttc aggagcgtaa aaatcttttt gttccaaagt taaagtaccg
    17941 gtttttttat ctcgcaagaa aagagataaa ttatcagatt cttgatgagc gacaatgata
    18001 taatcttcag ttttgttgaa attaaaatcg cgagggatat gaccttcagt atttgtccag
    18061 ccaatagttt caagttttgt accaagagga cttactttgt aagttgtcaa agaatcatgt
    18121 ccacgattag aagtatagag gaatttaccg tcagatgaaa tacggatggc agcaacacca
    18181 tttgctccat gataatcttc aggtagggtg ccaattgttt gaagacgagc aaagcgtcct
    18241 ttttcttcat tgtaacttaa aacttcaatt gttgaattta actctccaac caaataagcg
    18301 attttaccat ttggatggaa agtaatatga cgagcaccca ttcctttttc tgcccgataa
    18361 attgtagcaa tattgagttt accttcacca atgacatcat aaacagtgac ttcatctgtt
    18421 cccaaatcac aggtgacaag tcgtccgtca ggagtcaaat ccgaataatg aacgtgtgag
    18481 ctagattgct caggacgtgg cccagaaccg gtatgtttta ctgtatccgt taatcggagt
    18541 gagccattag cttgaatctt ataaacacga acttctccaa gatgatagtt cgctccgtaa
    18601 actaattggc gcgcttcgtc cacggcaaca tagcagagtg gagctcccgt ggttgtgaca
    18661 tttccgagat gagtagcagt ttcgccatca aaatcaaagg cggcgattcc tccaccatta
    18721 ctatctgctg cacaagtata gaggtgtccc ttttcatcga gagtgatata agtagggttt
    18781 tgaatcgcag cgacttcatt taatgatgat aattcagcag ctttagtgtc caaaagaaca
    18841 ctatatacgc ctttagatac acgttttgta tagccgccta aaaggatttt ttctttcata
    18901 tttctctcct cacaaactaa tttatttact ataattattt tatcacaaaa aaagcggttt
    18961 cagcaaaaat attaattttt tcttagaaaa aaatttaaaa acttactctt ttagtgatta
    19021 tagagcctaa attaacaatt aaatttgtca gacaatagga gtggctagaa aaatagattt
    19081 attgaacaat agaagcatga atagatactt gcaaaaatag gtcaaacaat gtataatgat
    19141 aaagttgcta tgcaaccatc tcgcatttcg tctcgacaaa gtcgtagtgt acgcaagtat
    19201 tgcggttgcg gatgacagat gaaagaggaa aaactatttt aaaaggagac attaacatgt
    19261 cagttatttc aatgaaacaa cttcttgaag ctggtgttca cttcggtcac caaactcgtc
    19321 gttggaaccc aaaaatgaaa ccatacatct tcacagaacg taatggtatc cacgttattg
    19381 accttcaaaa aactgtaaaa cttgttgacg atgcttacaa ctatgtaaaa aacgcttcac
    19441 aagaaggtgc agtagtcctt tttgttggta ctaaaaaaca agctgcagaa gcagttaaag
    19501 aagaagctct ccgcgctggt caatactacg taaaccaccg ttggttgggt ggtatgctca
    19561 ctaactggaa cactatccaa acacgtgtga cacgccttaa agaaatcaac aaaatggaag
    19621 aagaaggaac tttcgaagtt ttacctaaga aagaagtagt tcttcttaac aaagaacgcg
    19681 aacgccttga aaaattcatc ggtggtatcg ctgatatgcc tcgtattcca gatgttatgt
    19741 acatcgttga cccacatgct gaacaaatcg cagttaaaga agctaaaact ttggggattc
    19801 cagttgtagc aatggttgac acaaacgcag atccagaacc aatcgacgta gttattcctg
    19861 caaatgatga tgctatccgt gctgttaaat tgattacagc taaaatggca gacgctatca
    19921 ttgaaggacg tcaaggtgaa gatgcagcgg aagatttcgt agcagaagaa gcagcttcag
    19981 aagaatcact tgaagaactt gctgaaatcg ttgaaggtaa ataattttaa cttcaactta
    20041 tactaattaa gtaactacaa caggcgaggc cttacgcctc gcctgttttt ttaataaaac
    20101 tactgtcaat actgacagaa aaaacacata ggagatttac aaaatggcag taacagcagc
    20161 tcaagtaaaa gaattacgtg aaaaaactgg tgcagggatc atggacgcta aacgcgctct
    20221 tgttgaaact gacggaaata tggaagcagc agcagaactt cttcgtgaaa aagggattgc
    20281 gaaagcagct aaaaaagctg atcgtgtagc cgctgaagga cttacaggaa ttgccgtaaa
    20341 cggaaatgtt gcagcgattg ttgaattgaa ctcagaaaca gacttcgtag ctaaaaatga
    20401 tcaatttgtt gccttggtta aagaaatagc agagcttatt gcgtctaaaa aaccagcaac
    20461 taacgaagaa gcattggcac ttgaaacagc ttcaggtatt actcttgaag cagaacttgt
    20521 tcaagcgact gctacaatcg gagaaaaaat tactttccgt cgttttgcag taattgaaaa
    20581 aacagatgct caacactttg gagcttacca acataacggt ggtaaaattg gggttgtttc
    20641 tgtcgttgaa ggtgcagatg aaacacttgc taaacaacta tcaatgcata tcgctgcaat
    20701 gaaccctact gttctttcag ctgatgaact tgattcagaa tttgttaaag ctgaattagc
    20761 acaaatgaac cacaagattg atgaagacaa cgctagccgt gtacttgtta acaaaccaga
    20821 acttccacac catgaatttg gttctaagag ccaattaaca gaagaagttc ttgcagcagc
    20881 gaaagcttca tttgaagaag aacttaaagc tgaaggaaaa ccagaaaaaa tctgggacaa
    20941 gattcttcca ggtaaaatgg ctaaattcat cgttgacaat acaaaagttg accaacaatt
    21001 tgctcttctt gcacaacttt acatcatgga tgacagcaaa acagtcgaag ctttccttga
    21061 atcaaaagga gctaaagcaa ttgcattcac acgttttgaa gttggtgaag gaattgaaaa
    21121 agctgaaaca gacttcgcag cagaagttga agcagcaaaa gcaggacttt aatttaatta
    21181 aaaagcagcc tctagaggtt gcttttttta ttttgaaaat aaaaaagggc ttttcggtta
    21241 gaaaactaag aaaatagtgt atttctttga cgcaatatgc tataattata tttgagattt
    21301 tctatctatt taaaatctat ctaacctaag taattaaact atttttaagt aattaaatca
    21361 ttttatggag taaagcatgt caagtactgt cattatcctc attgttgtct tattagttat
    21421 tatcgtagcc ttttatgctt ttgcaatatt aatgcgaaag aaaacagaag accgtatact
    21481 agccttagaa gagcgaaagg aatcgctttt cgatttacct gttcaagaag aaattgattc
    21541 tgttaaaaaa atgcatcttg tcggacaatc gcaaacgatt ttccgtgaat ggaaccaaaa
    21601 atggcttgac ttatcatcaa attcttttgc tgatttggaa gaacatattt ttgaagctga
    21661 acaattaaac gattcattcc attttttccg tgctcgtgaa tctgtagcgg atagtgaggc
    21721 acaaattgaa ttaatggaag gtgatgtcga aggaattcgt caaggtgttg ctcaacttgt
    21781 tgaacaagaa aagcgtaatt caaataaaat tcaagagtcc cttgatttat atgataactt
    21841 acgtagcgat attgctgaca atgcagattt gtatggaaca gttattactg aacttgaaaa
    21901 acatttagcc aatatcgaaa cagaattttc tcagtttgta acgctaaact caacaggtga
    21961 tccgattgaa gcggctgaag ttttggagac tgctgaagaa catacgattg ctttacgtgc
    22021 aattacagag caaattccat catttattaa aacaattgaa aaagatgttc ctaaacgact
    22081 tgaagaattg caagaagcga gtgataaatt cgttgcagaa gaatacattc ttcccgataa
    22141 tgtcaacatt aaagaaagaa tggatgattt acatgatcat ctcgttgaaa gtagttcatt
    22201 attagaacaa tttgaactag atcgagtgga agctgaactt ggtttaattc aagaaaaagt
    22261 tgaagaactt tatgctattt ttgaaagaga atatagcgca cgtcgaaatg ttgaaaaacg
    22321 ttcatcagtt ctcaaagaat atattgaaca tatcagagca aataataaaa atcttctcct
    22381 tgaaattgac catgttacac aagcctatat cctttctgga aacgaaaaag gatatgttag
    22441 aggttatcaa gaacatttag aatctcttga ctcagatgtt gatgaaattc taggaaatat
    22501 tcaagctaaa acaatgcctt actcaattct ttcacgtaga gtaaactcag tagtcaatgc
    22561 gcttgaagat attgagaaga accaaattaa gattagtgat acccttacag gactcagaga
    22621 tgaagaaaga gcagctcaag aaatcgcaga acgctttgat tctgaactcc gtacaataaa
    22681 acgttatgtt gaaaaatgta atctccctgg tcttcctaaa gattatctcg acttgttctt
    22741 cacaacagga gatcgagtac aaaatctttt caaagaatta ggacgagtta gaatcaacat
    22801 tgatacaatt aatcatcttg ttgacgtaag cactgaagat atgcacgttt taaaagaagc
    22861 aacgactaat ttgactgacc atgcggtatt agctgaacaa ttgattcaat atgctaatcg
    22921 ttataaagct gcaaatgaac aagtagcaca agggatctca agagcgcttc aattatttga
    22981 aaacagccgt gactatgatg gttcatttga tgaaatttca aaaacgctag aacttgtaga
    23041 accgggtgca gcttctagaa tttcaggagt ttattttaaa aataaaccta ctcctgatta
    23101 cttataaaat aaataaaagc aaggtaaata gccttgcttt tatttattgg gttataaatt
    23161 ctgaatattc gcataatata gttaggtaaa acatgtaaaa attattataa tgtaataaaa
    23221 gccataaaaa tgtcttggaa ggatagatat gaaaatagct cattataata agatgccccc
    23281 tgactgttta ttagatatac actcgccacc tcctatcaat ttactaatta atcaaataaa
    23341 gataatataa aaggagaact ttccaatgac atattacttg gaagaagagg attttgaaaa
    23401 tcttttttca gaaatgaaac ctatagttat gaaattaatg aaacaaattc gcattagaac
    23461 atggaaaata gaggattatc ttcaagaggg gatgattatt ttacatcttc tattagaaga
    23521 gcagagcgat ggtcaaaagc tgcatacaaa atttaaggta aagtatcatc aaagattaat
    23581 agatgaatta agacgaagtt atgcaaagaa acgaagccat gaccatttta taggtttaga
    23641 tgtttatgaa tgctcagact ggataaattc aggtgatact agtccagata atgaagtggt
    23701 cttcaatcat ttgctggcag aagtatatga aggtttgagc gcacattatc aagagttact
    23761 acttcgacaa atgcgaggag aagaactaac tcgcatggaa cggtatcgcc ttcgtgaaaa
    23821 aataaaggct attttatttt cagaagacga agagtgaaga ggaattccct attttagtaa
    23881 aaatagggag ttttttgata aga
//
