LOCUS       NZ_JAQDYA010000007     25090 bp    DNA     linear   CON 22-FEB-2024
DEFINITION  Lactococcus lactis strain AM113-80 PF3HH22005.Scaf7, whole genome
            shotgun sequence.
ACCESSION   NZ_JAQDYA010000007
VERSION     NZ_JAQDYA010000007.1
KEYWORDS    WGS; RefSeq.
SOURCE      Lactococcus lactis
  ORGANISM  Lactococcus lactis
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Lactococcus.
REFERENCE   1  (bases 1 to 140799)
  AUTHORS   Lin,X., Hu,T., Chen,J., Liang,H., Zhou,J., Wu,Z., Ye,C., Jin,X.,
            Xu,X., Zhang,W., Jing,X., Yang,T., Wang,J., Yang,H., Kristiansen,K.,
            Xiao,L. and Zou,Y.
  TITLE     The genomic landscape of reference genomes of cultivated human gut
            bacteria
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 140799)
  AUTHORS   Zou,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-NOV-2022) BGI Reaserch, BGI-Shenzhen, Beishan
            Industrial Zone, Shenzhen 518083, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. v2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100x
            Sequencing Technology             :: MGI
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/22/2024 02:49:03
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,400
            CDSs (total)                      :: 2,354
            Genes (coding)                    :: 2,325
            CDSs (with protein)               :: 2,325
            Genes (RNA)                       :: 46
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 29
            CDSs (without protein)            :: 29
            Pseudo Genes (ambiguous residues) :: 0 of 29
            Pseudo Genes (frameshifted)       :: 9 of 29
            Pseudo Genes (incomplete)         :: 18 of 29
            Pseudo Genes (internal stop)      :: 7 of 29
            Pseudo Genes (multiple problems)  :: 4 of 29
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:07:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 25090
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAQDYA010000007.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..25090
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..25090
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25090
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[9145:15090](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(9146..15090)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            complement(<1..506)
                     /locus_tag="PGT72_RS09495"
                     /pseudo=""
     CDS             complement(<1..506)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012897362.1"
                     /locus_tag="PGT72_RS09495"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="GGDEF domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MFISILANMSILLVSLYGYLSYYVNYNKFHSLLKDKGTFFNSIFV
                     TIVGIFLLYFAIEIGGARYDLRFLLLAFTVKYFGNKVTITSTLLLMVIRLFWGVDNHTP
                     IAICYSVLLVFTLPMLKFIVSKINSDIIQLLILNYYCLLIGNFLNAIIIKNPLRDINIY
                     LHLYV"
     gene            complement(551..1261)
                     /locus_tag="PGT72_RS09500"
     CDS             complement(551..1261)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012897361.1"
                     /locus_tag="PGT72_RS09500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="EAL domain-containing protein"
                     /protein_id="WP_270342822.1"
                     /transl_table=11
                     /translation="MQDYNDLFYLIYQPIVNIKNNGTLEILEYEVLLRSQDKRRFPNKE
                     FNEILFSPEKHQMFMKWYFEKLNDILVRNKNINLAINIHPLQWKEPIIFDFFYKLKEFS
                     NRIKIELTEHRNFIEFDLDMVFKSRYAELVMLGYNFVIDDVGNGTNDVDFVIKHIEQVS
                     SIKFSILPFRDIKKESLILFIEAWFHLAKEFDKEFVVEGIECKILSSYLLNMGIRLQQE
                     FLFGEGKSHVALSK"
     gene            complement(2047..2691)
                     /locus_tag="PGT72_RS09505"
     CDS             complement(2047..2691)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014570415.1"
                     /locus_tag="PGT72_RS09505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transporter"
                     /protein_id="WP_270342823.1"
                     /transl_table=11
                     /translation="MIRSECLKLKNSLGFYLVFLFTLLELLTVPIYLAFGRSHVSMTDL
                     SLMIFLFFPLLVTILSILIFEQESLANHFQEINVNKKSSRIWLSKLIVVDFLLFFPSAM
                     IWIITGVSQGVGQQGMMIATASWLMAIFLNHFHLLLTFIINRGGSMIIAIIEILLIIFA
                     SNKVLLAAYWCPIALPVNFMITGRCAHLIAAVGWIVLSTIILVALSKKKIR"
     gene            complement(2678..3406)
                     /locus_tag="PGT72_RS09510"
     CDS             complement(2678..3406)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017864241.1"
                     /locus_tag="PGT72_RS09510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lantibiotic ABC transporter permease"
                     /protein_id="WP_017864241.1"
                     /transl_table=11
                     /translation="MKRIIASEAIKLKKSGTLRLVLIIPFVTLFIAFLMGGIQIFSVFS
                     IYWWEAGFLFLLMSLLFLYDKKSEEQAGNFQNVKWKKLSWKIHLAKMLLIWLRGILASI
                     VLIILLYLVAFVFQGIVVVDFMKVSVALIAILLAASWNLPFIYLIFKWINTYVLLAANT
                     LICLIVAPFVAQTPVWFLLPYTYHYKVTESLLNIKPSGDLLTGKINFSIWEVLLPVGLS
                     IVVTIGVSYLLKGVIEHDKK"
     gene            complement(3408..4085)
                     /locus_tag="PGT72_RS09515"
     CDS             complement(3408..4085)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012897845.1"
                     /locus_tag="PGT72_RS09515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_270342824.1"
                     /transl_table=11
                     /translation="MQVKIQNLSKTYKEKQVLQDISFDIKSGTVCGLLGVNGAGKSTLM
                     KILFGLISADTGKIFFDGQEKTNNQLGALIEAPAIYMNLSAFDNLKTKALLFGISDKRI
                     HETLEVIGLAETGKKRAGKFSLGMKQRLGIGMAILTEPQFLILDEPTNGLDPDGIAELL
                     NLILKLKDKGVTILISSHQLHEISKVASQIIILNKGKIRYNHANNKEDDIEQLFFKIVH
                     GGM"
     gene            complement(4184..5527)
                     /locus_tag="PGT72_RS09520"
     CDS             complement(4184..5527)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017864239.1"
                     /locus_tag="PGT72_RS09520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="WP_270342825.1"
                     /transl_table=11
                     /translation="MGKKYSMRRRIWQAVIEIIIGTCLLILLLLGLTFFLRQIGQISGS
                     ETIRLSLDSDNLTISDIECDMKHYPYDYIIFDNDTSKILGGHYVKSDVPSFVASKQSSH
                     NITEGEITYTYSSNKHFSVVLRQNSMPEFTNHTLRSISYNQFTYLFFFLGEIILIIFSV
                     YHLIREFSKNFQAVQKIALKMGEITTFPEQEESKIIEFDQVLNNLYSKSKELAFLIEAE
                     RHEKHDLSFQVAALSHDVKTPLTVLKGNIELLEMTEVNEQQADFIESMKNSLTVFDKYF
                     NTMISYTKLLNDENDYKARISLEDFLIDLSVELEEFSTTYQVDYQLVKKTDLTTFYGNT
                     LALSRALINIFVNACQYAKEGEKIVSLSIYDDEKYLYFEIWNNGHPFSEQAKKNAGKLF
                     FTEDTGRSGKHYGIGLSFAQGVALKHQGNLILSNPQKGGAEVILKIKK"
     gene            complement(5520..6206)
                     /locus_tag="PGT72_RS09525"
     CDS             complement(5520..6206)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014734918.1"
                     /locus_tag="PGT72_RS09525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_270342878.1"
                     /transl_table=11
                     /translation="MYKILIVDDDQEILKLMKTALEMRNYEVATHQNISLPLDITDFQG
                     FDLILLDIMMSNIEGTEICKRIRREISTPIIFVSAKDTEEDIIKGLGIGGDDYITKPFS
                     LKQLVAKVEANIKREERNKHAVHVFSEIRRDLGPITFYLEERRVCVNGQTIPLTCREYD
                     ILELLSQRTSKVYTREDIYDDVYDEYSNALFRSISEYIYQIRSKFAPYDINPIKTVRGL
                     GYQWHG"
     gene            complement(6275..8323)
                     /locus_tag="PGT72_RS09530"
     CDS             complement(6275..8323)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014570410.1"
                     /locus_tag="PGT72_RS09530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="S8 family serine peptidase"
                     /protein_id="WP_270342828.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 2.2e-48, bitscore:
                     158.0, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKILGFLFIVCSLGLSATVHGETTNSQQLLSNNINTELINHNSN
                     AILSSTEGSTTDSINLGEQSPAVKSTTRTELDVTGAAKTLLQTSAVQKEMKVSLQETQV
                     SSEFSKRDSVTNKEAVPVSKDELLEQSEVVVSTSSIQKNKILDDKKNRANFVTSSQIIK
                     EKPSNSKGASGVIDNSASPLSYRKAKEVVSLRQPLKNQKVEAQPLLISNSSEKKASVYT
                     NSHGFWDYQWDMKYVTNNGESYALYQPSKKISVGIIDSGIMKEHPDLSNSLGNYFKNLV
                     PKGGFDNEEPDETGNPSDIVDKMGHGTEVAGQITANGNILGVAPGITVNIYRVFGENLS
                     KSEWVARAIRRAADDGNKIINISAGQYLMISGSYDDGTNDYQEYLNYKSAINYATAKGS
                     IVVAALGNDSLNIQDNQTMINFLKRFRSIKVPGKVVDAPSVFEDVIAVGGIDGYGNISD
                     FSNIGADAIDAPAGTTANFKKYGQDKFVSQGYYLKDWLFTTTNTGWYQYVYGNSFAAPK
                     VSGALALVVDKYGIKNPNQLKRFLLMNSPEVNGNRVLNIVDLLNGKNKAFSLDTDKGQD
                     DAINHKSMENLKESRDTMKQEQDKEIQRNTNNNFSIKNDFHNISKEVISVDYNIKQKMA
                     NNRNSRGAVSVRSQEILPVTGDGEDFLPALGIVCISILGILKRKTKN"
     gene            complement(8325..9062)
                     /locus_tag="PGT72_RS09535"
     CDS             complement(8325..9062)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014570409.1"
                     /locus_tag="PGT72_RS09535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NisI/SpaI family lantibiotic immunity
                     lipoprotein"
                     /protein_id="WP_270342830.1"
                     /transl_table=11
                     /translation="MRKYLILIVALIGITGLSGCYQTSQKKVRFDEGSYTNFIYDNKSY
                     FVTDKEIPQENVNNSKVKFYNLLIVDMKSEKLLSSSNKNSVTLVLNNIYEASDKSLCMG
                     INDRYYKILPESDKGAVKALRLQNFDVTSDISDDNFVIDKNDSRKIDYMGNIYSTSDTT
                     VSDEELGEYQDVLAEVRVFDSVSGKSIPRSEWGRIDKDGSNSKQSRTEWDYGEIHSIRG
                     KSLTEAFAVEINDDFKLATKVGN"
     gene            complement(9146..10303)
                     /locus_tag="PGT72_RS09540"
     CDS             complement(9146..10303)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /locus_tag="PGT72_RS09540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_270342831.1"
                     /sec_met_domain="LANC_like (E-value: 1.7e-70, bitscore:
                     230.5, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKNIKRNVEKIIAQWDERTRKNKENFDFGELTLSTGLPGIILM
                     LAELKNKDNSKIYQKKIDNYIEYIVSKLSTYGLLTGSLYSGAAGIALSILHLREEDEKY
                     KNLLDSLNRYIEYFVREKIEGFNLENITPPDYDVIEGLSGILSYLLLINDEQYDDLKIL
                     IINFLSNLTKENKGLISLYIKSENQMSQSESEMYPLGCLNMGLAHGLAGAGCILAYAHI
                     KGYSNEASLSALQKIIFIYEKFELERKNQFLWKDGLVADELKKEKVIREASFIRDAWYY
                     GGPGISLLYLYGGLALDNDYFVDKAEKILESAMQRKLGIDSYMICHGYSGLIEICSLFK
                     RLLNTKKFDSYIEEFNVNSEQILEEYGDESGTGFLEGISGCILVL"
     gene            complement(10296..12098)
                     /locus_tag="PGT72_RS09545"
     CDS             complement(10296..12098)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015425980.1"
                     /locus_tag="PGT72_RS09545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_270342832.1"
                     /transl_table=11
                     /translation="MDEVKEFTSKQFFNTLLTLPSTLKLIFQLEKRYAIYLIVLNAITA
                     FVPLASLFIYQDLINSVLGSGRHLINIIIIYFIVQVITTVLGQLESYVSGKFDMRLSYS
                     INMRLMRTTSSLELSDYEQADMYNIIEKVTQDSTYKPFQLFNAIIVVLSSFISLLSSLF
                     FIGTWNIGVAILLLIVPVLSLVLFLRVGQLEFLIQWQRASSERETWYIVYLLTHDFSFK
                     EIKLNNISNYFIHKFGKLKKGFINQDLAIARKKTYFNIFLDFILNLINILTIFAMILSV
                     RAGKLLIGNLVSLIQAISKINTYSQTMIQNIYIIYNTSLFMEQLFEFLKRESVVHKKIE
                     DTEICNQDIGTVKVINLSYVYPNSNAFALKNINLSFEKGELTAIVGKNGSGKSTLVKII
                     SGLYQPTMGIIQYDKMRSSLMPEEFYQKNISVLFQDFVKYELTIRENIGLSDLSSQWED
                     EKIIKVLDNLGLDFLKTNNQYVLDTQLGNWFQEGRQLSGGQWQKIALARTFFKKASIYI
                     LDEPSAALDPVAEKEIFDYFVALSENNISIFISHSLNAARKANKIVVMKDGQVEDVGSH
                     DVLLRRCQYYQELYYSEQYEDNDE"
     misc_feature    12075..12090
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            complement(12109..12984)
                     /locus_tag="PGT72_RS09550"
     CDS             complement(12109..12984)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03891.1"
                     /locus_tag="PGT72_RS09550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_270342833.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 5.2e-23, bitscore:
                     75.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLFIRTRALGNEGRAFIREKRVSVERREKFPFNEWLYLKLYISIN
                     RQNEFLLSYLPDIQKIVANLGENLFFLRYTDPKPHIRLRIKCSDLFLAYGSILEILKRS
                     RKNRIMSTFDISIYDQEVERYGGFDTLELSKAIFCADSKIIPNLLTLIKDTNNDWKVDD
                     VSILVNYLYLKCFFQNDNKKILNFLNLVSPKKVKENVNEKIEHYLKLLKVDNLGDQIFY
                     DKNFKELKHAIKNLFLKMIAQDFELQKVYSIIDSIIHVHNNRLIGIERDKEKLIYYTLQ
                     RLFVSEEYMK"
     gene            complement(13099..15090)
                     /locus_tag="PGT72_RS09555"
     CDS             complement(13099..15090)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.4"
                     /locus_tag="PGT72_RS09555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_270342835.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 3.2e-86, bitscore:
                     282.8, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 6.7e-09,
                     bitscore: 29.4, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKSSFKAQPFLVRNTILSPNDKRSFTEYTQVIETVSKNKVFLEQ
                     LLLANPKLYNVMQKYNAGLLKKKRVKKLFESIYKYYKRSYLRSTPFGLFSETSIGVFSK
                     SSQYKLMGKTTKGIRLDTQWLIRLVHKMEVDFSKKLSFTRNNANYKFGDRVFQVYTINS
                     SELEEVNIKYTNVYQIISEFCENDYQKYEDICETVTLCYGDEYRELSEQYLGSLIVNHY
                     LISNLQKDLLSDFSWDTFLTKVEAIDEDKKYIIPLKKVQKFIQEYSEIEIGEGIEKLKE
                     IYQEMSQILENDNYIQIDLISDSEINFDVKQKQQLEHLAEFLGNTTKSVRRTYLDDYKD
                     KFIEKYGVDQEVQITELFDSTFGIGAPYNYNHPRNDFYESEPSTLYYSEEEREKYLSMY
                     VEAVKNHNIINLDDLESHYQKMDLEKKSELQGLELFLNLAKEYEKDIFILGDIVGNNNL
                     GGASGRFSALSPELTSYHRTIVDSVERENENKEITSCEIVFLPENIRHANVMHTSIMRR
                     KVLPFFTSTSHNEVQLTNIYIGIDEKEKFYARDISTQEVLKFYITSMYNKTLFSNELRF
                     LYEISLDDKFCNLPWELIYRDFDYIPRLVFDEIVISPAKWKIWGRDVNNKMTIRELIQS
                     KEIPKEFYIVNGDNKVYLSQENPLDMEI"
     aSDomain        complement(14404..14667)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_PGT72_RS09555_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="1.50E-09"
                     /identifier="RREFam001.1"
                     /label="PGT72_RS09555"
                     /locus_tag="PGT72_RS09555"
                     /protein_end="229"
                     /protein_start="141"
                     /score="29.4"
                     /tool="antismash"
                     /translation="FTRNNANYKFGDRVFQVYTINSSELEEVNIKYTNVYQIISEFCEN
                     DYQKYEDICETVTLCYGDEYRELSEQYLGSLIVNHYLISNLQK"
     gene            complement(15198..15371)
                     /locus_tag="PGT72_RS09560"
     CDS             complement(15198..15371)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_a"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014570405.1"
                     /locus_tag="PGT72_RS09560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="gallidermin/nisin family lantibiotic"
                     /protein_id="WP_270342836.1"
                     /sec_met_domain="TIGR03731 (E-value: 1.6e-23, bitscore:
                     75.5, seeds: 23, tool: rule-based-clusters)"
                     /sec_met_domain="mature_a (E-value: 7.6e-07, bitscore:
                     21.5, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTKDFNLDLVSVSKKDSGASPRITSISLCTPGCKTGALMGCNMK
                     TATCNCSIHVSR"
     CDS_motif       complement(15303..15371)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSTKDFNLDLVSVSKKDSGASPR"
                     /locus_tag="PGT72_RS09560_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(15198..15302)
                     /prepeptide="core"
                     /locus_tag="PGT72_RS09560_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="26.70"
                     /molecular_weight="3341.0"
                     /monoisotopic_mass="3338.6"
                     /core_sequence="ITSISLCTPGCKTGALMGCNMKTATCNCSIHVSR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSTKDFNLDLVSVSKKDSGASPR"
                     /leader_location="[15302:15371](-)"
                     /alternative_weights="3359.0"
                     /alternative_weights="3377.0"
                     /alternative_weights="3395.0"
                     /alternative_weights="3413.1"
     misc_feature    complement(15840..15859)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 19.7"
                     /tool="antismash"
     misc_feature    15904..15924
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 24.64"
                     /tool="antismash"
     misc_feature    complement(16403..16419)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: weak, score: 20.28"
                     /tool="antismash"
     gene            16751..17023
                     /locus_tag="PGT72_RS09565"
     CDS             16751..17023
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017864233.1"
                     /locus_tag="PGT72_RS09565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="(4Fe-4S)-binding protein"
                     /protein_id="WP_270342837.1"
                     /transl_table=11
                     /translation="MDNSKLFGEAANEEQLLKNDYHKYRGENMDIYYNVAICEHAGECV
                     RGNPLVFEVSRKPWIIPDNGDVASNQSVINRCPSGALKYLAKEKN"
     gene            17023..17295
                     /locus_tag="PGT72_RS09570"
     CDS             17023..17295
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257361.1"
                     /locus_tag="PGT72_RS09570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_017864232.1"
                     /transl_table=11
                     /translation="MNIIERENLFELLSDKGEVIGEMAYMPMNNSIIITHTGVSLDYRG
                     QGLAKKLVLAGIQKARREQLKLGATCPYAVKYFREHKEELTDVLK"
     gene            17532..18902
                     /gene="brnQ"
                     /locus_tag="PGT72_RS09575"
     CDS             17532..18902
                     /GO_function="GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA]"
                     /GO_process="GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene="brnQ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129615.1"
                     /locus_tag="PGT72_RS09575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="WP_058203230.1"
                     /transl_table=11
                     /translation="MEEKLAGKDYLFIGSMLFGLFFGAGNLIFPIHMGQEAGAAISQAN
                     FGFLITAVGFPFLGIIALGISQSNGVFELASRVNRIYAYIFTILLYLVIGPFFALPRLA
                     TTSFEIGISPFLSHELQAPLLALFSILFFGTAWFLSRKPTKLLDYIGKFLNPLFLVLLG
                     IILVIAFTHPLGKVSQAEIGKAYQASPILTGFTQGYNTLDALAALAFGIIIITTIRQRG
                     VKNPKIIAKETIKAGLISVGLMAIIYTCLSYLGTMSLGQFAISENGGIALAQISNHYLG
                     NFGMIILALIVIIACLKTAVGLMSAFSETFAELFPKKEYRFYLLIVSILPCIFANIGLT
                     KIIELSVPVLMFLYPLAIILILLALLSPLFKHSRLVYQITTAFTLLAAIIDGLNALPAS
                     LHTITFISVIINFAKDFLPFFSLGMGWILPAVLGFIIGCLCQIAITVYKNKKSSTLS"
     gene            complement(18980..20434)
                     /locus_tag="PGT72_RS09580"
     CDS             complement(18980..20434)
                     /GO_function="GO:0005518 - collagen binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017864230.1"
                     /locus_tag="PGT72_RS09580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LPXTG cell wall anchor domain-containing protein"
                     /protein_id="WP_270342839.1"
                     /transl_table=11
                     /translation="MKAKNKSFKLLMVLSLLMCLVGINLFKPSNVFAADYGNKFITGHE
                     LTDDLGNPKTDFGIYDDVQAHWDFDIPVGSVSQGDTMSVNVPDLLTLSKDITFEIKDEA
                     GNIIGTAVANHLTGVVTVTFSKLVENATSDIKGSFSVWVNWDEQKVEEDTRVVVDWKDG
                     GTTEVNIGPATGPDKDEVLYKWGWVDDNDSTLIHWQVRINYAKENIQKAIYTDIIGGNQ
                     NLVSGSISVANVTYSSDRENYNVDSYYPQASILENGMNGFTVNLGDISNTIIIDYSTRA
                     TDGGLSQQYENRGELTGENIEKQVVEVHTPNNGGNGNASMKLSISGEKTWIDDNNARGL
                     RPSFISIELYRNGEKVDSRDVTAKENWKYSFTNLDKYDESGKLYDYDVKEVSVSNYTSQ
                     QEGYNFINTIIPVKEETPEKPDQSITTPSSSSQVMSVSSSSMESETSEELPKTGDSPRD
                     FFKVLGILLLISGGLEMIYIRRKSKI"
     misc_feature    complement(20423..20432)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 16.78"
                     /tool="antismash"
     gene            complement(20461..21354)
                     /locus_tag="PGT72_RS09585"
     CDS             complement(20461..21354)
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017864229.1"
                     /locus_tag="PGT72_RS09585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_270342840.1"
                     /transl_table=11
                     /translation="MKFSKKNIFLILMFGLIAILVFMSTRETKKYVQDGKKEQPDFAYE
                     SLLKDNDGIIVLCYHRVLKDTVVTNFAYSISHNSQLHEYNVFLQDFEQQMTFLKKNHIK
                     VLTSSELIEKLNKKEVIGKAVVITFDDIDKSLPENAYPIMKKLDLPFTQFIITGKVGQT
                     IDGSQMSTWKEIKKMNENPLITSGLHTNDLHYQENFEPILSTNISKKVVQEDYQKSQKA
                     FGEKLDQKGKVFAYPYGAQNKDLEDYMLQDGIQGIFTLSPGVVTNETLYSNIPRLIVMK
                     DNWKTIKHWLLSEGTQ"
     gene            complement(21627..22847)
                     /locus_tag="PGT72_RS09590"
     CDS             complement(21627..22847)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123: polyprenol-monophosphomannose synthase ppm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017864227.1"
                     /locus_tag="PGT72_RS09590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_270342842.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 5.3e-31,
                     bitscore: 100.8, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIISTMVDVYVVYYPIILSFIWASGAFLSRWKERDKKAIDETKEF
                     EKISIVISAYNEEETIEEVLLSLRNLNYPSLEIFIVDDKSRDRTLEKLYEVKKSFDDWE
                     TLTILEQKENKGKATALNVALQQVNSKYMLVIDADSYLSKDALSYLLAELTSSSDIGAV
                     TGRPIVRNRTTLLGKLQTLEYLSVIDAIKRAQSLFLGAIMTVSGVIVMYRVEALKEIGG
                     FNTEVMTEDIDVTWRLHRNQWKVKYVPKALSYILVPENLKSLLKQRRRWAVGGVEVLIS
                     NLSWVFKRGEFKHRFLLIEMICSHIWSWFFLIESYQYFLQMLLNQEFKVSGQIIVIFVL
                     ISFFVFFLGLNNDKGESRLSLTDKLIFPAYLVAYWFLNLISALSAELVVLTNRTNKGKW
                     ESPDRGV"
     gene            complement(22852..23883)
                     /locus_tag="PGT72_RS09595"
     CDS             complement(22852..23883)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129606.1"
                     /locus_tag="PGT72_RS09595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyltransferase"
                     /protein_id="WP_270342844.1"
                     /transl_table=11
                     /translation="MKRNSSIDLMKSCAIFFVISVHFLLNSGFYDMTIHSTLAIFWIGI
                     RTILITCVPLFLVATGFLMNRKELSAQYVLGIVPVIISYIGISLLVWGVQSLVGKGSDF
                     STAINGIFDYSTDSYSWYVEMYLGLYLFIPLLNIIWNYKKEIKNYHLYIVFIASLLTFL
                     PSLLNSFGKVIPDYWQICYPVSYYFIGAYLYTYQNEIKKISIGKLVTAFLSALTIFTLT
                     DTFASWNQEFQWLDHNDYFGYQTAIMTVLVIAILWRTPIPKWSVRLLKALSTATLTIYL
                     ISDLTDQFVYGFFKHEIPNLSQRVIAGPIIIPVAFTSAALLGIFVGKVLNFPFKRKKER
                     KEN"
     misc_feature    24299..24312
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 21.61"
                     /tool="antismash"
ORIGIN
        1 atgacatata aatgcagata aatatttatg tccctaagtg gatttttaat aattatagca
       61 ttcaaaaaat tcccaattaa taaacagtag taattcaaaa ttaagagttg aataatatca
      121 ctattaattt tacttacaat aaattttagc atgggtaagg taaataccaa tagtacacta
      181 taacaaatag caataggtgt atgattatct acaccccaaa ataatcttat aaccattaat
      241 aatagagtgc tcgttatagt aactttattt ccaaaatatt taacagtaaa tgctaataaa
      301 agaaatctta aatcatacct agcaccacca atttcaattg caaagtacaa taaaaaaatc
      361 cctacaatag ttacaaaaat tgaattaaaa aaagttcctt tgtctttcaa aagagaatga
      421 aacttgttat aattcacata atagcttaag taaccataaa gagaaactaa taaaatgctc
      481 atatttgcta aaatactaat aaacatccaa tactccctaa atttataaat acaaaattaa
      541 aaaaatcttt ttatttactt aaagcaacat gacttttacc ttcaccaaat agaaattcct
      601 gttgtaatct tatccccata tttaataagt atgaggagag tattttacac tcaatacctt
      661 caaccacaaa ttccttatca aattctttcg ccaaatgaaa ccatgcttca ataaataata
      721 ttaaagattc tttttttata tctcgaaaag gcaatatgga aaattttata ctagaaactt
      781 gttctatatg tttgataaca aagtctacat catttgttcc attcccgaca tcatcaatta
      841 caaaattata tccaagcata actaattcag catatcttga tttgaatacc atatcaagat
      901 caaattctat aaaatttcta tgttcagtta actcaatttt tattctattt gaaaactctt
      961 ttaacttata aaaaaaatca aaaattatag gttccttcca ttgtaaggga tgaatgttta
     1021 tagccaaatt aatattttta tttctaacta agatatcatt aagtttttca aaataccact
     1081 tcataaacat ttggtgtttt tcaggtgaaa ataaaatttc attaaattcc ttatttggaa
     1141 aacgcctttt atcctgagat cgaagtagaa cctcatattc taaaatttct aatgttccat
     1201 tatttttaat atttactatt ggttgataaa taagataaaa taaatcatta tagtcttgca
     1261 tctacacatt ctcctatatc tttactttta cattgggatg aatatttaag taacttctgc
     1321 tcattattat aattgtaaaa atttttgctg gctatttttt atgataaaag atagagttta
     1381 cttttaagct ttctttcgct acatttttcc aatcttaaaa atataggata taaaataaaa
     1441 tagtttgtat gctattgatt gaaaaaacta gttgaataat aaatatttat gcctctaaga
     1501 tttatatgta aatttgattt aatattttca actacaaaag cctactgtaa atttacagta
     1561 ggcttatgat aaagtagatg ctgtatagtt ttgctttggt tcattttatt attatcaacg
     1621 atacatcttt taattctagg ttaaaatgca ctttatatgt ctatcaaaaa taatgaaaaa
     1681 tccaagtatt tatacttgga ttttttattg tttaattttc tcttttatat agaaactcat
     1741 attcttcaca aataactggc atatcagttt aaaaatgtta tatgctttaa agaatctctc
     1801 atgagcttga caccaataac tccaaaagaa aaagtgtaag tcgataggaa accactttat
     1861 aaaaaattac tgagaaaaga aaactaacga cgaaaacatt attcttagag taagaactgt
     1921 cacatattga tagaaatttt attcaaactt atgagtctaa aggtactttg aataaattaa
     1981 tatagacaga aataagagat aaatagcaaa aacatattag gtcgaattac cataagaaaa
     2041 aatactttat ctaatctttt ttttagataa tgccacaaga attattgtgg ataaaacaat
     2101 ccaccctacg gcagctatca gatgagcaca ccgcccagtt atcataaaat taacaggtaa
     2161 agcaatagga caccaataag ctgctaataa aactttatta ctggcaaaaa taatgagtaa
     2221 tatttcaata atagcgataa tcatgctccc tcctcgattg attataaagg tcaataaaag
     2281 atgaaaatga ttaagaaaaa ttgccatcaa ccagctagct gttgcgatca tcattccttg
     2341 ttgccctact ccctgtgaaa ctcccgtaat tatccagatc attgctgatg gaaagaataa
     2401 aaggaaatcc actactatta gctttgataa ccaaattctg ctactttttt tatttacatt
     2461 tatttcttgg aaatgattgg ccagactctc ctgttcaaag attagaatag acaaaattgt
     2521 aaccagtaac ggaaaaaaca aaaaaatcat gagcgacaaa tcagtcattg aaacatgact
     2581 tcttccaaaa gctaaataaa taggaaccgt taaaagctct aataaagtaa agagaaaaac
     2641 taaataaaac cctaagctat tttttaattt gagacattca cttcttatca tgttctatca
     2701 ctcctttaag taaatacgaa actcctatcg ttacaactat ggaaagtcca actggtaata
     2761 aaacttccca aatactgaaa tttatcttcc ctgttaacaa atctcctgat ggtttgatat
     2821 ttaacaaact ttctgtaact ttatagtgat aagtgtatgg tagcaagaac catactggag
     2881 tttgtgcaac aaaaggggca acaattaaac aaatcaaggt attcgcagct aacaatacgt
     2941 aggtattaat ccacttgaaa atcaagtata taaagggtaa attccaagaa gctgctagta
     3001 atatagcaat caatgccaca cttactttca taaaatccac cactacaata ccttgaaaca
     3061 caaaagcaac caaataaagc aaaataatca agactatgct cgctagtata cctcttagcc
     3121 aaatcaacaa cattttggcc aaatgaattt tccaactcag ctttttccat ttcacatttt
     3181 gaaaatttcc agcttgctcc tctgattttt tatcataaag aaaaagcaaa ctcatcaaaa
     3241 ggaataaaaa accagcttcc caccaataaa ttgaaaaaac actaaaaatc tgtattccac
     3301 ccataagaaa tgctataaat agagtcacaa aagggataat taataccaat ctaagagttc
     3361 ctgatttttt taattttatt gcttctgatg ctattattct tttcatatca cattcctcca
     3421 tgcacaatct taaagaataa ctgttcaatg tcgtcttctt tattgttcgc atgattataa
     3481 cgaatcttac ctttgttcaa aataataatt tgactagcta ctttacttat ttcgtgcaac
     3541 tgatgactag aaatcaagat tgtcacacct ttatctttaa gttttaagat taagtttaac
     3601 aactccgcaa taccatcagg atccaaacca ttagtaggtt catcaagaat taaaaattga
     3661 ggttctgtaa gaatagccat accaattccc aaacgttgtt tcatccctaa agagaatttt
     3721 cctgctcttt tctttcctgt ttctgccaaa ccaatcactt ctagagtttc atgaattctc
     3781 ttatctgaaa ttccaaaaag caaagcctta gttttaagat tatcgaaagc agataaattc
     3841 atatatattg ctggagcctc gattaaggct ccaagttgat tatttgtctt ttcttgtcca
     3901 tcaaaaaaaa tttttccagt atctgcagaa attaaaccaa acaaaatttt catcaaagtt
     3961 gattttcctg caccgttaac tcctaataaa ccacagactg ttccagattt aatatcaaaa
     4021 ctgatatctt gtagcacctg cttttcttta tatgttttag aaagattttg aatttttacc
     4081 tgcattatat ttcctcactt tattttatgt ttaaaaaaag tatataaaac aattttcaga
     4141 atctattcag aaacaaaaaa agtaatcctt agagattact aaattacttt tttattttta
     4201 ggataacttc tgccccacct ttttgaggat tactgagaat taagtttcct tgatgtttta
     4261 aagctacacc ttgagcaaaa gatagtccaa tcccatagtg tttcccacta cgtccagtat
     4321 cttctgtgaa aaatagtttt ccagcatttt tttttgcttg ttcagaaaaa ggatgaccat
     4381 tattccagat ttcaaaatag agatattttt catcatcata aatactcaaa ctgactattt
     4441 tttcaccctc tttagcatac tgacaggcat taacaaagat attgataagt gctcgactta
     4501 aagctaatgt atttccgtaa aaagtggtta aatctgtttt tttaactagc tgataatcca
     4561 cttgataagt tgttgagaac tcttccaact caactgataa atctatcaaa aaatcctcca
     4621 gggagattct cgctttgtaa tcattttcat cattcaaaag ttttgtataa ctaatcattg
     4681 tgttaaaata cttgtcaaaa acagtcaaac tatttttcat tgactcaata aaatcagctt
     4741 gttgttcatt tacttcagtc atctctagca gttcaatatt tccttttaat actgttaaag
     4801 gtgtcttaac atcatgtgaa agtgcagcaa cctggaagga taaatcatgc ttttcatgac
     4861 gctccgcttc aataaggaaa gctaactcct tacttttcga atataagtta ttcagaacct
     4921 gatcaaattc aataattttt gattcctctt gttcaggaaa agtagttatt tcccccatct
     4981 tcaatgcaat cttttgaacg gcttgaaaat tcttagaaaa ttctctaatg agatgataga
     5041 cagaaaaaat aatgagtatt atttcaccaa gaaaaaagaa aaggtaagta aattgattat
     5101 aagaaattga acgaagcgta tgatttgtaa attctggcat actgttttgt cttaaaacaa
     5161 ctgaaaaatg cttattgctt gaataagtat aagtaatttc tccttctgta atattatgtg
     5221 aagactgttt tgaagctaca aaactaggta catccgactt gacataatgt cctcccaaaa
     5281 ttttacttgt atcattgtca aaaataatat aatcatatgg gtagtgtttc atatcacatt
     5341 cgatatcaga aatagttaaa ttatctgaat ctaaagataa acgaatagtt tctgaaccac
     5401 tgatttgtcc aatttgtcgt agaaagaaag tcaagcccag taacaacagg ataagtagac
     5461 aagtacctat gataatttca atgacagctt gccatatccg tcgacgcatt gaatattttt
     5521 tacccatgcc actgataccc aagtccccga accgttttta tcggattaat atcgtatggt
     5581 gcaaacttac tcctaatctg ataaatatac tccgagattg accgaaaaag tgcattagaa
     5641 tattcatcat atacgtcatc ataaatatcc tctctcgtat aaactttaga agttcgttgt
     5701 gatagtaatt caagaatatc gtattcacga caagtcagtg gaattgtttg accattgaca
     5761 cagactcgcc tttcttctaa ataaaatgta attggtccta aatctctacg aatctctgaa
     5821 aaaacatgaa ctgcatgttt attgcgttcc tctcgcttta tatttgcttc cacttttgca
     5881 accaactgtt taaggctaaa aggcttagta atatagtcat ccccaccaat acctaagcct
     5941 tttataatat cctcttctgt atctttcgca ctaacaaaga taattggagt tgatatttct
     6001 ctgcgaatcc ttttacaaat ttcagtccct tcaatatttg acatcatgat atctaacaaa
     6061 atcaaatcaa atccctgaaa atcagtaata tccaagggaa gtgaaatgtt ttgatgcgtc
     6121 gcaacttcat agtttctcat ttctaatgct gtcttcatta attttaaaat ttcctgatca
     6181 tcatcaacta ttaaaatttt atacaccact ttacctccga ttgtttagta ctcattactt
     6241 cattatacca ttcattctga agaaatataa tctatcaatt tttagtcttt cttttcaata
     6301 taccaagaat tgagatacac actataccta aagcaggtaa aaaatcttct ccatctccag
     6361 taacaggtaa aatttcttga cttcgtacag aaacagcacc tctcgaattt cgattattag
     6421 ccattttttg cttaatatta taatcaactg aaattacttc ttttgaaatg ttatgaaaat
     6481 catttttgat agaaaaatta ttatttgtat ttctttgaat ttctttatct tgttcctgtt
     6541 tcattgtatc cctagactct ttaagattct ccatcgattt atggttaata gcatcatcct
     6601 gacctttatc tgtatctaag ctaaaagctt tatttttccc attcaataaa tcaacaatat
     6661 tcaatactct attcccatta acttctggag aattcattag aagaaacctt tttagttggt
     6721 taggattctt tattccatat ttatcaacta ctaatgccag tgccccagat actttaggag
     6781 cagcaaatga gttgccataa acatattggt accagccagt attagtagtt gtaaaaagcc
     6841 aatctttcaa ataataaccc tgactgacaa atttatcttg cccatatttt ttaaaattgg
     6901 ccgttgtgcc agcaggagca tcaattgcat ccgctccaat attactaaaa tcagaaatat
     6961 taccataacc atctattcca cctacggcta ttacatcctc aaatacactc ggtgcatcta
     7021 caacttttcc aggaaccttt atacttctga aacgcttaag aaagtttatc attgtttggt
     7081 tatcttgtat gtttaaacta tcattaccaa gagctgcgac aacaatactt ccttttgctg
     7141 ttgcataatt tattgctgac ttataattaa gatactcttg ataatcattt gttccatcat
     7201 catacgatcc tgaaatcata agatactgtc cagcacttat attgatgatc ttgttcccat
     7261 catccgcagc tcttcttatt gctctagcta cccattccga tttcgaaaga ttttcaccaa
     7321 atactctgta tatatttaca gtaatccctg gtgctactcc taaaatatta ccatttgctg
     7381 taatctgacc tgcgacttcc gtcccgtgtc ccattttgtc cacaatatca cttggatttc
     7441 cagtttcatc aggttcttca ttatcaaacc ctcccttagg aacaagattt ttaaaataat
     7501 ttcctaaact atttgacaaa tcaggatgtt ctttcatgat tcctgaatca ataattccaa
     7561 cagaaatttt ctttgagggc tggtagagcg catagctttc tccattattt gtcacatatt
     7621 tcatatccca ctgataatcc caaaaaccat gtgaatttgt ataaacactt gctttctttt
     7681 cagaagaatt acttatcaat agaggttgtg cctctacttt ttgatttttt aaaggttgtc
     7741 taagagatac cacttcctta gctttacgat aagatagagg agaagcagaa ttatcaatta
     7801 caccagatgc acctttagaa tttgatggtt tttccttaat aatctgagag gaagtaacaa
     7861 agttagctct attcttctta tcatcgagga ttttattttt ttgaatcgat gatgttgaaa
     7921 cgactacttc actttgctca agtagctcat ccttagatac tggaactgct tctttatttg
     7981 taacgctatc tctcttactg aattcagaac taacttgagt ttcttgcaac gaaactttca
     8041 tttctttttg aacagctgat gtctgtaata aagttttagc agcaccagtt acatccaatt
     8101 cagtccttgt tgtcgatttt actgcaggtg actgctcccc tagattaatc gaatcagtcg
     8161 ttgatccctc tgttgaagat aaaattgcat tagaattatg attaattaat tccgtattaa
     8221 tattatttga gagtaactgt tgtgaatttg ttgtctcccc atgcacagtt gctgataaac
     8281 ccaacgaaca aacgataaaa aggaaaccta gtattttttt cactctagtt tcctaccttc
     8341 gttgcaagct taaaatcgtc atttatctca acggcaaatg cttcagtaag agattttcct
     8401 ctaatagaat ggatttcgcc ataatcccat tccgtcctac tctgtttgga atttgaacca
     8461 tccttatcaa ttctccccca ttcagacctc gggatacttt tgccactaac tgaatcaaat
     8521 acacgtactt cagctaaaac atcctgatat tctcccaatt cttcatcaga tacggtggtg
     8581 tccgatgtac tgtaaatatt tcccatatag tcaatttttc gtgaatcatt tttatcaata
     8641 acaaaattat catcagaaat atcgcttgtc acatcaaagt tttgtaatct caaagctttg
     8701 accgccccct tatcactttc tggaagtatc ttatagtatc tgtcgttaat acccatacat
     8761 agcgacttgt cagaagcctc ataaatatta tttaagacca aagtcacact atttttgttg
     8821 ctacttgata aaagtttctc acttttcatg tcaacaatca acaggttata aaattttact
     8881 ttggaattgt taacgttctc ctgaggaatc tccttatcag ttacgaaata cgatttatta
     8941 tcataaataa aattagtata acttccttcg tcaaacctca cctttttttg acttgtttga
     9001 taacaccctg ataaacctgt tatccctatt aaggccacaa taagtattaa atattttctc
     9061 attttctctt ccctcctttc aaaaaatcat caaaaagtaa cagtgcttgt ctccaataag
     9121 taaaattgat tgaatattca aatttctata ataccagtat acagccactt attccttcaa
     9181 gaaaacccgt gccactttca tctccgtatt cttcaagaat ttgctcacta ttaacattaa
     9241 attcttctat gtatgaatca aacttttttg tatttaatag ccgcttaaat aaagaacaaa
     9301 tttctattaa accagaatag ccatggcaaa tcatatatga atcaatacca agttttcttt
     9361 gcatagctga ctctaatatt ttttctgctt tatctacaaa atagtcatta tccagtgcta
     9421 atcctccgta taagtatagc agactaatac ctggacctcc atagtaccat gcatctctaa
     9481 tgaaacttgc ttccctaatt actttctctt tttttaattc atctgctaca agtccatctt
     9541 tccatagaaa ctgatttttc ctttcaagtt caaacttttc ataaataaaa ataatttttt
     9601 gcaaagctga caacgaggct tcattactat atccttttat gtgggcataa gctaagatac
     9661 agcccgctcc agcaagtcca tgtgctaatc ccatattcaa acagcctagt ggatacatct
     9721 cactttctga ttgagacatc tgattctccg atttgatgta aagcgatatt agtcctttgt
     9781 tttctttagt cagatttgat aaaaaattga taatgagtat tttcaaatca tcatattgct
     9841 cgtcgttgat taataataga taggaaagta tcccagataa accttcaatc acgtcataat
     9901 caggaggagt aatgttttcc aaattaaatc cttcaatttt ttctctgacg aaatattcga
     9961 tatatctatt taggctgtca agaagattct tatatttttc gtcttcttct cgtaaatgta
    10021 ggatacttaa tgcaatgcca gctgctcccg aataaagcga tcctgttaaa agcccatatg
    10081 ttgaaagttt gctaacaata tattcaatat aattgtctat ctttttctga tatatctttg
    10141 agttatcttt attttttaac tccgctaaca ttaaaattat accaggcaat cctgtagaga
    10201 gagtcaactc tccgaaatcg aagttttctt tattttttct agttctctca tcccattgag
    10261 caataatttt ttcaacattt ctttttatat tttttttatt catcattatc ctcatattgc
    10321 tctgaataat aaagttcttg atagtattga catcttctca aaaggacatc atgacttcca
    10381 acatcttcga cctgtccatc tttcataacc acgattttat ttgcttttct ggcagcattc
    10441 aaactatgag aaatgaaaat tgaaatatta ttttccgaaa gagcaacaaa ataatcaaat
    10501 atttcttttt cagctacagg atcgagtgca gcacttggtt catctaaaat ataaattgaa
    10561 gctttcttaa agaatgtcct tgctaatgca attttttgcc actgacctcc tgaaagttga
    10621 cgcccttctt gaaaccaatt tcctaactgc gtatcaagta catattgatt attagttttc
    10681 aaaaaatcga gtcctaaatt atctagtact ttaataattt tctcatcttc ccattgagaa
    10741 gacaaatcac tcaatcctat attctctctt atcgttaact catacttcac aaaatcttgg
    10801 aacagcaccg atatgttttt ctgataaaac tcctcaggca tcaaactact tctcattttg
    10861 tcgtattgga ttattcccat agttggttga tataatcctg aaattatctt tactagtgta
    10921 cttttccctg aaccattttt tcctacaata gcagttaatt ctcctttttc aaaggataaa
    10981 ttgatattct ttagtgcaaa ggcattcgaa ttagggtaaa catatgataa attaattact
    11041 ttaacagttc ctatatcttg attgcatatt tcagtatctt ctattttttt gtgaactaca
    11101 ctttctctct ttaaaaactc aaaaagttgt tccataaaca aactagtatt ataaatgatg
    11161 taaatatttt gaatcattgt ttgagaataa gtattgattt tagaaatagc ttgtatgaga
    11221 cttaccaaat tacctataag aagttttcct gctcttaccg aaaggatcat agcaaatatc
    11281 gtaagaatat ttatcaaatt caaaatgaaa tcaagaaaaa tattgaaata tgtcttctta
    11341 cgagcaatag ctaaatcttg gttgataaat cctttcttta attttccaaa tttatgaatg
    11401 aagtaattgc taatattatt taatttgatt tctttaaatg aaaaatcatg agtcaataaa
    11461 tatacaatat accatgtttc tctttcagaa cttgctctct gccactggat taaaaactct
    11521 aattgtccca ctctgagaaa aagtaccaaa gataatactg gaacaataag gagtaaaatt
    11581 gctaccccaa tgttccatgt tccaataaaa aatagactag ataacaatga gataaacgat
    11641 gaaagcacaa caatgatagc attaaatagc tgaaaaggct tgtaagtgct gtcttgagta
    11701 actttttcta tgatattata catatcagcc tgctcataat cacttaattc aagagatgag
    11761 gtagtcctca tgaggcgcat attgatactg taagaaagtc gcatatcaaa ttttccacta
    11821 acataacttt ccagctgtcc tagaactgtt gttatcactt gaacaataaa atagatgata
    11881 ataatattga taagatgtct ccctgaacct agcacagagt ttattaaatc ttgataaata
    11941 aaaagactag ccaacggaac aaaagctgtg atagcattta gcacaattaa ataaattgca
    12001 taacgttttt ccaactgaaa aattaacttc aaggtgcttg gaagagtaag taaagtatta
    12061 aaaaattgtt ttgatgtgaa ttctttcact tcatccatct attagtcctc atttcatgta
    12121 ttcttccgaa acaaacaacc tttgaagtgt gtaataaatt aatttctctt tatctcgttc
    12181 aataccaatt agtcggttat tatggacatg aatgatactg tcaataattg aataaacttt
    12241 ctgaagttca aaatcttgag ctatcatttt taaaaataaa ttttttatgg catgctttaa
    12301 ttctttaaaa ttcttgtcat aaaaaatttg gtcacctaga ttatcaactt tcagaagctt
    12361 aagataatgt tcaatctttt cattgacatt ttctttaacc tttttaggac taactaaatt
    12421 caaaaaatta agaatctttt tgttatcatt ctgaaagaag catttcagat ataaataatt
    12481 caccaagatt gatacatcat cgactttcca atcattatta gtatctttta tcaatgtaag
    12541 caaatttgga ataattttag aatcggcaca aaatattgct ttggataact ctaaagtatc
    12601 aaatccacca tatctttcta cttcttggtc ataaatagaa atatcaaaag ttgacattat
    12661 cctatttttc cgactccttt ttaagatttc aagaatagat ccgtaagcta aaaataaatc
    12721 tgaacatttt atacgcaatc taatatgtgg tttaggatca gtatatctta ggaagaatag
    12781 attttcaccc aggtttgcta ctattttctg aatatctgga agatacgaca gtaaaaattc
    12841 attttgacga tttatagaaa tgtacaactt gagataaagc cactcgttaa agggaaattt
    12901 ttcacgccgt tcaaccgaaa ctcttttctc tcttataaat gctctccctt cattacctaa
    12961 tgctctcgtt ctaataaaaa gcactacaac atcggcaact ctcccctttt gtcctttatt
    13021 tatgatattt tcatcttcaa aatattcttg tagctctata aaatcttttc tttttgagct
    13081 cttctttatc gccgactctc aaatttccat atccaatggg ttttcctgtg ataaataaac
    13141 tttattatct ccattgacaa tataaaactc tttgggaatt tctttgcttt gaataagttc
    13201 tcttattgtc atcttattat ttacatccct tccccaaatt ttccatttag caggagatat
    13261 tactatttcg tcaaatacta aacgtggaat ataatcaaag tctctgtaaa taagttccca
    13321 aggtaaatta caaaacttgt catctaatga aatttcgtaa agaaatctta gctcattact
    13381 gaataacgtt ttattgtaca tgcttgtaat gtagaatttc aatacctctt gagttgaaat
    13441 gtctcgtgca taaaattttt ctttttcgtc tattccaata tagatattag ttaactgaac
    13501 ttcattgtga cttgtacttg taaaaaatgg aagtactttc ctcctcataa ttgatgtatg
    13561 cataacgtta gcatgtctga tattttctgg aagaaatact atttcacacg atgtaatttc
    13621 tttattctca ttttctcttt cgacagaatc tactatcgtt ctatgataac ttgttaactc
    13681 cggagagagt gcagaaaatc tacctgatgc ccctcccaaa ttattatttc caacgatatc
    13741 ccctaaaata aaaatatctt tttcatactc ctttgccaaa ttcaaaaata attctaaccc
    13801 ttgaagttca cttttctttt ctaagtccat tttttggtaa tgagactcta agtcgtcaag
    13861 attaattata ttatgatttt taacggcttc tacatacatg ctgaggtact tttctctctc
    13921 ctcttctgaa tagtatagag tactcggttc ggactcataa aagtcatttc gaggatgatt
    13981 ataattatat ggagctccta tgccaaatgt agaatcaaat aattctgtta tttgtacttc
    14041 ttgatctaca ccatattttt cgataaattt atccttatag tcatccaaat atgttcttct
    14101 tacagatttt gtcgtatttc ctaaaaactc agctaaatgt tctaattgtt gcttttgttt
    14161 aacatcaaaa tttatttcac tatcactaat taaatcaatt tgaatataat tatcattctc
    14221 aagaatttgt gacatttcct gatatatttc tttcagtttc tcaatacctt caccaatttc
    14281 tatttctgag tattcttgaa taaacttttg aacttttttc agaggaatta tatatttttt
    14341 atcttcatct attgcttcaa ctttagtcaa aaaagtgtcc caagaaaaat ctgacaacaa
    14401 atctttttgt aaattagaga tcaaataatg attaactatc agactgccaa gatattgttc
    14461 cgatagttct ctatattcgt ctccatagca aagcgttaca gtttcacaaa tatcttcata
    14521 tttttgatag tcattctcac aaaattcaga aataatttga taaacattcg tatatttaat
    14581 atttacttct tcaagctcac tactatttat ggtataaact tgaaaaactc gatctccaaa
    14641 cttataattc gcattatttc tagtaaatga taactttttt gagaaatcta cttccatttt
    14701 atgaactagg cgaatcaacc actgagtatc caatcttata ccctttgtag tctttcccat
    14761 taacttgtac tgtgaacttt tcgaaaaaac accaattgaa gtttcactaa ataatccaaa
    14821 tggagttgat cgtaaataac ttctcttata atacttgtaa atagattcaa ataatttttt
    14881 aacccttttc ttctttaaca gaccagcatt atatttctgc ataacattat agagtttagg
    14941 attagctagt agtaactgtt ccaaaaaaac tttattttta cttacagtct caatgacttg
    15001 agtatattca gtaaaactcc gtttatcgtt tggagataat attgtatttc ttactaaaaa
    15061 cggttgagct ttaaatgaac tttttatcat gttttttcct ctctttattt ttataagcta
    15121 tttagcaacc ctaaataact tataaaaata ggatagtatc catgtctgaa ctaacaaaat
    15181 actatccttt gatttggtta tctgcttacg tgaatactac aattacaagt tgctgttttc
    15241 atgttacaac ccatcagagc tcctgtttta caaccgggtg tacatagcga aatacttgta
    15301 atgcgtggtg atgcacctga atctttcttc gaaacagata ccaaatccaa gttaaaatct
    15361 tttgtactca ttttgagtgc ctccttataa tttattttgt agttccttcg aacgaaatca
    15421 ttgtatctaa caaacttcag aatttaatca gagccgttta ttatgctcgc gttatcgaca
    15481 ataatattat tgccaatact ttctcaagat agaattaaga ctgttttaga tttgttaatg
    15541 tttctattgt cagtatagtt ataagactag gtcattcaag tatgtctaag actcaataaa
    15601 cctatctcta tattattcag gaactagaaa atcaagatat taataaaatt attaaatatt
    15661 cgtcaactat aacttaaata aatatttttt gtaaaagaga ttattctaat gattttaact
    15721 tgttaatttt aggctaatta agagtgatgg tatcgtcgag gcgtttaaag aatagtccaa
    15781 cttctgttgt tcctcataat ttgaaacatt cagaactcaa tcgtttacaa ttaatcatga
    15841 taggttcact tgtcctcccc ataaatattt atctattcat ctatttatct atttatctat
    15901 ttgtttttgt cattttaacg attggataat aacaaaaacc atcaaaatag taaatactat
    15961 catgaaactc aatgactgag atacatttga taaggttact gccgaacgtg cctaaaaata
    16021 aggtgacggt gattttaatc taagttattg gcgtcaaact catgagagat tccttaaaac
    16081 acatagtatt tttaaacccg atatgccaat tatttgttaa gaatacgagc ttgtatacaa
    16141 aaaagggaat taaacaataa aaaatccaag cataaatacc tggataaaaa gtctaacttt
    16201 tggggtgcac atcaattcat ttatttagac tatctcactt aagagttatt tgtaaattta
    16261 ctttaatatt ttaaactaca aaacctacta taaattttac agtaggtttt ggataaagta
    16321 aatgctgtat agttttgctt tggttagttc tttggttcac tttattttta ttaatagtaa
    16381 atcttttaaa actaggttaa aacgcacttt atatgtgtat caaaaatttc cattatctta
    16441 tttgaaattc cttctccgta attttttaag caaaaaattt tccaatttat tactagagtt
    16501 tttttctttt ttattaatct gtcattgatt aattaatttt acttttattt aatcaaccct
    16561 aaaacatatt ttcatttttt tccaagacaa aaaagtcaat aagcatttat attataacat
    16621 atctgtatat ctctttcatc tcttcctaga cccctatatt attttttaat gctttctata
    16681 gatatcattc tgataaagca gcttgacaaa tgtcatataa aaaaatacaa tcgtaaacag
    16741 gaggaagaaa atggataatt caaaattatt tggcgaagct gcgaatgaag aacaactatt
    16801 gaaaaatgat tatcataagt atcgtggtga aaacatggat atttattata atgtagcaat
    16861 ttgtgaacat gcaggtgaat gtgttagagg aaatccttta gtatttgaag ttagccgtaa
    16921 gccttggatt atccccgata atggcgatgt cgcttccaat caatcagtaa tcaatagatg
    16981 cccttctgga gcactaaaat atttggcgaa ggagaaaaac taatgaacat tattgaaaga
    17041 gaaaatctat ttgaactcct gtcagataaa ggagaagtca ttggcgaaat ggcctatatg
    17101 cctatgaata attcaataat aatcactcat actggcgttt cacttgacta tcgcggtcaa
    17161 ggcctagcca aaaaattagt tcttgccgga atccaaaaag caagacgcga acaattaaaa
    17221 ttaggagcca cttgccccta tgccgtcaaa tatttcagag aacataaaga agaattaact
    17281 gatgttttaa aataagctac tccttaaata taaaagacct tttagcgggg ccttttttat
    17341 gtattctaaa ttaagcaaga gaaaaaattt tcttcaaact ttactttaac actgaattta
    17401 cttggtaatt taaaaggctt aataaaatca atcgtcatgt tttctataaa attgtattgt
    17461 aaattcacaa tttttttgct ataataattc attattttat ctatcaaaca aatcaattat
    17521 aaggagtatt tatggaggaa aaattagctg gtaaagatta cctctttata gggtcaatgt
    17581 tattcggact tttctttggt gctggaaatt taatttttcc aatacatatg ggtcaagaag
    17641 ccggagccgc tatttcacaa gcaaattttg gttttttaat tacagcagtc ggctttccct
    17701 ttttaggaat tatcgctctg ggaatttctc aaagtaacgg ggtttttgag ttagcttccc
    17761 gagtcaatcg tatttatgct tatattttta caattttact ttatctcgtt attggcccct
    17821 ttttcgctct tcctcgctta gcaactactt cttttgaaat tggaatttca ccttttttaa
    17881 gtcatgaact ccaagctcca ctattggctc tttttagtat ccttttcttt ggaaccgcct
    17941 ggtttctgtc tagaaagcca acaaaactct tagattatat cggaaaattt ttaaatcccc
    18001 tctttttggt tttgttaggt attattttgg tcattgcttt cactcatcca ttaggaaaag
    18061 ttagccaagc agaaattggt aaagcctatc aagcatctcc tattttgaca ggtttcacac
    18121 aaggttacaa tactcttgat gccttggccg ccttagcttt tggaatcatt atcatcacaa
    18181 ctattcgcca acgtggcgta aaaaatccta aaattattgc aaaagaaacc ataaaagctg
    18241 gcctcatcag tgtaggacta atggctatca tttacacctg cctttcttac ctaggtacta
    18301 tgagtcttgg gcaatttgct attagtgaaa atggtggaat tgctctcgct caaatttcca
    18361 accactactt aggaaatttc ggcatgatta tcttagcact cattgtcatc atcgcttgct
    18421 taaaaacagc cgttggctta atgtctgcct tttctgaaac ctttgccgaa ttatttccta
    18481 aaaaagaata ccgtttttat ctcctcatcg taagtattct tccttgcatc tttgcaaata
    18541 ttggtttgac aaaaattata gaactttcag ttccagtcct catgttttta tatcccttag
    18601 ccattatcct tattttatta gctttattaa gcccgctttt taaacattct agactcgttt
    18661 atcagataac aactgctttt acacttttag cggctattat cgacggactc aatgctcttc
    18721 cagccagtct tcacacaatt actttcatat cagtaataat taattttgct aaagactttc
    18781 tacccttttt ctccctagga atgggttgga ttcttccagc ggttttaggc tttatcatcg
    18841 gatgtttatg tcaaatcgcg attactgtat ataaaaataa aaagtcttca acactttcat
    18901 aaaagttgag agcctacaat atataaaaag gagtttcaaa taattgataa ctccttttct
    18961 tttacatcaa ctcagataat taaatttttg attttctcct aatataaatc atttcaagcc
    19021 ccccagaaat caatagaagt attcccaaca ctttgaaaaa atcccttggg ctatcccccg
    19081 ttttaggcaa ctcttcagat gtttctgatt ccattgaaga agacgaaacc gacattactt
    19141 gtgaggatga actaggagta gtaattgatt ggtcgggttt ttcaggagtt tcttctttaa
    19201 cagggatgat tgtatttata aaattatacc cctcttgttg actcgtgtaa ttactaacag
    19261 acacctcttt tacatcataa tcgtaaagtt tcccactttc atcatactta tccaaattgg
    19321 taaacgaata tttccaattt tctttagccg tcacatctcg tgaatcaact ttctctccat
    19381 tccgatataa ctcaatacta ataaaacttg gtcttaaacc acgtgcatta ttgtcatcaa
    19441 tccaagtttt ctctccagaa atagaaagtt tcatacttgc atttccattt ccaccattgt
    19501 taggagtatg aacttctact acctgttttt caatattttc tcccgtcaat tctcctctat
    19561 tttcatactg ttgagaaagc cctccatccg ttgccctcgt tgaataatcg ataataatcg
    19621 tatttgaaat atcacctaaa ttcacggtaa atccgttcat gccattttct aaaatactag
    19681 cctgaggata atagctatca acattataat tctctctatc actactataa gtcacattag
    19741 ctaccgaaat cgaaccagaa actaaattct gattcccacc aataatatca gtataaatag
    19801 ctttctggat attttcttta gcataattga tccgaacctg ccaatgaatt aaggttgaat
    19861 cattatcgtc aacccatccc catttataaa gtacctcatc tttatccggt cctgttgccg
    19921 gaccaatgtt aacctctgtt gttcctccat ctttccaatc aactactacc cttgtgtctt
    19981 cctctacttt ttgttcatcc caattaaccc aaacggaaaa tgaaccttta atgtctgaag
    20041 ttgcattttc aacaagtttt gaaaaagtaa cagttaccac ccccgtaaga tgattagcaa
    20101 ccgccgttcc gataatattt ccagcttcat cttttatttc aaaagtaata tcttttgata
    20161 aagttaataa atcaggaaca ttgacactca ttgtatcccc ctgagaaacg cttcccactg
    20221 gaatatcaaa atcccaatga gcctgaacat catcataaat accaaaatct gttttcggat
    20281 ttcccaaatc atcagtcagt tcatgtcccg ttataaattt atttccatag tcagcagcaa
    20341 atacatttga aggtttaaat aaattaattc caaccaagca catcaataaa ctcagaacca
    20401 ttaataattt aaatgactta ttcttcgcct tcatgaatat ctccttctta ttttctctta
    20461 ttattgtgtc ccttcactta agagccaatg tttgatagtt ttccaattat ccttcataac
    20521 aatcaaccta ggaatattac tatatagtgt ttcattagtc actacacctg gagatagtgt
    20581 gaatattcct tgaattccat cttgtagcat ataatcttct aagtctttat tttgtgctcc
    20641 atagggataa gcaaaaactt ttcctttttg atctaacttc tcaccaaatg ctttctgact
    20701 tttttggtaa tcttcttgca ctactttttt tgaaatatta gtagataaaa tcggttcaaa
    20761 gttttcttga taatgtaagt cattcgtatg cagccctgaa gtaatcaaag gattttcatt
    20821 cattttcttt atttctttcc aagtcgacat ttgtgaacca tcaatggttt gtccaacttt
    20881 tcccgtgata atgaattgcg taaagggtaa gtctaatttt ttcattattg gataagcgtt
    20941 ctctggcaaa gacttatcaa tgtcatcaaa agtaatcact actgctttgc caatcacctc
    21001 ttttttatta agcttctcta tcagttctga actagtcaaa actttaatat gatttttctt
    21061 taaaaatgtc atttgctgtt caaaatcttg caagaataca ttatattcat ggagttgaga
    21121 attatgcgaa attgaataag cgaaatttgt aaccaccgta tcttttaaca cacggtgata
    21181 acaaagaaca ataattccat cattgtcttt aagcaaactc tcataagcaa aatctggctg
    21241 ctcctttttt ccatcttgta catatttttt tgtttcacgt gtggacataa acaccaagat
    21301 agcaataaga ccaaacatca atatcaaaaa aatattcttt ttactaaatt tcatattata
    21361 aatctaagtc tccttcgtta aaatataaag actaggaatc gttaatattg aaagaagaca
    21421 aaacaaatca taaattatat cttcccaatt tgttattgga aacccaatga ttacaaaaac
    21481 agagataatt ccatcactat atatccccag caaagagatt aataaaagaa cgaaaacaat
    21541 taatataaac agccaacata gtgaaacagc caagaattcc aaaaaatgtc gttttttcat
    21601 ttttttacgt attactaatt ccattattac acccctctat caggactttc ccattttcct
    21661 ttatttgtcc gattagttaa aacaacaagt tcagcagaaa gagcactaat caaatttaga
    21721 aaccaataag caacaagata agctggaaat attaatttat cagtcaagga taagcgactc
    21781 tcccctttat cattattaag tcctaaaaag aatacaaaaa atgaaataag aacaaaaatc
    21841 acgataattt gacccgatac tttgaattct tgatttaaca gcatttggag aaaatactga
    21901 taagattcta ttaagaaaaa ccaactccaa atatgactac aaatcatttc aatcaaaaga
    21961 aaccgatgtt taaattctcc tcttttaaaa acccatgata aatttgagat taatacttct
    22021 actccaccaa ctgcccatct tctccgttgc tttaaaagag attttaaatt ttcaggaacg
    22081 agaatatagc ttaaggcttt agggacatat ttgactttcc attgattacg atgaagtcgc
    22141 caagtgacat caatgtcttc cgtcatcact tcggtattaa agcccccaat ttctttcaaa
    22201 gcctctacac gatacataac aatcacacct gatacggtca ttattgcacc tagaaaaaga
    22261 ctttgtgctc tcttaatcgc atcaatcaca cttaaatact ctaaggtttg taatttcccc
    22321 aatagagttg ttctgtttct aacaataggt cgtccagtca cagccccaat atctgaacta
    22381 gaagttaatt cggccaataa ataagataga gcatctttag aaagatatga atccgcatca
    22441 ataacaagca tatacttgct gttaacttgt tgcaaagcaa catttaaagc cgtggctttt
    22501 cccttatttt ccttttgctc aagaatagtt aatgtttccc aatcgtcgaa agattttttt
    22561 acttcataaa gtttctccaa agtgcggtcc ctactcttat catcaacaat aaagatctct
    22621 agggaagggt aatttagatt acgtagtgat aataaaactt cctcaatcgt ttcttcttca
    22681 ttgtacgcag aaataacaat actaattttt tcaaattctt ttgtttcatc aattgctttc
    22741 ttatctcttt ctttccaccg agataaaaaa gcaccacttg cccaaatgaa ggacaagata
    22801 atcggataat aaacaacata aacatctacc attgttgaga ttatcatagt tttaattttc
    22861 ctttctttct ttttttctct taaaagggaa atttaaaact tttcccacaa aaattcctag
    22921 taatgccgca ctagtaaagg ctactggaat aataatcggt cctgctatca ctcgttgact
    22981 taagtttgga atttcatgct taaaaaatcc atagacaaac tgatccgtta aatcggatat
    23041 aagatagata gtcaaagtag cggtagatag agcctttagc aacctaacgc tccattttgg
    23101 aatgggagtt ctccacaaga ttgctataac taatactgtc attatggctg tttgataacc
    23161 aaaataatca ttgtggtcta gccactgaaa ttcttgattc caacttgcaa aagtgtccgt
    23221 caaagtaaaa atcgtaagtg cacttaagaa tgctgtaaca agttttccta ttgaaatttt
    23281 ctttatttca ttttgataag tataaaggta agctccaata aaataataac taacgggata
    23341 acaaatttgc caatagtctg gaataacttt tccaaaacta tttaataaag agggtaagaa
    23401 tgttagcaaa cttgcgataa agacgatata taaatgataa ttttttattt cttttttata
    23461 attccagata atatttaata aagggataaa aagataaagt cctaaataca tttcaacata
    23521 ccaagagtaa gaatcggttg aataatcaaa aattccattt atggctgtgg agaagtcgct
    23581 tccttttccg acaagagatt gaactcccca tactaataaa gatatgccta tatatgaaat
    23641 gatgacagga actattccca gaacatattg agcacttaat tcttttcgat tcattaaaaa
    23701 tccagttgcc actaaaaaca agggcacaca agtaattaaa atcgttctta tcccaatcca
    23761 aaaaattgct aaagtggaat gaattgtcat atcataaaag cccgaattta ataaaaagtg
    23821 gaccgaaatg acaaagaata ttgcacaact tttcattaaa tctattgatg aattacgttt
    23881 cattttttta tatttatagc agaaaaattt tgctcctata aatcctttct ctaatttggg
    23941 ttataaaccg ctcaattcaa aatttacaat tatttttcct ttacatcact aagatgtctc
    24001 gaaattatgt tattctccta actttaattt agtatggatt tataactaac gaaaatcatt
    24061 aatttttgat tgcaatccac caacttatca cagtataaca taacaaaaag aaatattgta
    24121 atataaagct tacaaaatta cttaatatca tcatattatt catttttaat tattattaac
    24181 ccctataaag taaaatatca atcaataaaa aagcggtaca cccccttata aactggcact
    24241 tatgatggtt ttaggcatat taggcaatac tctaaattgc aaatttagaa atcaaaaaca
    24301 aacatcagtt tgtaattagt aacataaaaa aagtacttac tcaagtaagt acttttttgc
    24361 attgatttac catattttta ttttaaaaac ttcttttatt cctgacaata ttaatgtagg
    24421 tagagcagga ataaaaatca caagtagata tacaggtaat gttaactgag cagttcccat
    24481 cacactattg aaaaacggaa tgattgttac taaaaatgaa gaaactcctg caaataacac
    24541 tgctccaaca agtctaatat tcccaaaagg attacgtcta aacaatgttc ttgaacttct
    24601 tgcatcaaat acatgccata attgtccata aactaaagtc agaaaagcaa ctgtttgtgc
    24661 ttcactagcg ttcaatccat tttgagcagc caggagaaat ccaagataaa ccatcgctcc
    24721 cataactgtt cccctaatca aaaccctaga ccacgtgtgg ttagcaagaa tagattcatt
    24781 agggttccgt ggtttttctt tcatcaaatc tgtttcggca acatcataac ccaaagaaaa
    24841 agatggaatc gcatcactca ccatattaac ccaaagaacc attaaagcag tcaatgtcgg
    24901 agtcattgct gctacatttc caacactact tctaaataaa actaaaccta atacaagagc
    24961 caaaacttca gcaacatttg ttgtcagttc gtgtctcata aagtttttta tattagcata
    25021 gatagtacga ccgctataaa ctgatttttc tatcgttgta aatttatcat ctaataaaat
    25081 gagatctgca
//
