LOCUS       NZ_CP115450            22448 bp    DNA     linear   CON 17-DEC-2024
DEFINITION  Kitasatospora cathayae strain HUAS 3-15 chromosome, complete genome.
ACCESSION   NZ_CP115450
VERSION     NZ_CP115450.1
KEYWORDS    RefSeq.
SOURCE      Kitasatospora cathayae
  ORGANISM  Kitasatospora cathayae
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Kitasatospora.
REFERENCE   1  (bases 1 to 8860963)
  AUTHORS   Zheng,Y., Mo,P., Li,J., Zhou,Z., Huang,K., Luo,Y., Xie,P. and
            Wang,Y.
  TITLE     Kitasatospora cathayae sp. nov., a novel endophytic actinomycete
            isolated from the leaves of Cathaya argyrophylla
  JOURNAL   Int J Syst Evol Microbiol 74 (5) (2024)
   PUBMED   38809239
REFERENCE   2  (bases 1 to 8860963)
  AUTHORS   Mo,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-DEC-2022) College of Life and Environment Science,
            Hunan University of Arts and Science, No. 3150 Dongting Avenue,
            Changde, Hunan 415000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 8.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 155.15x
            Sequencing Technology             :: Oxford Nanopore PromethION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_027627435.1-RS_2024_12_16
            Annotation Date                   :: 12/16/2024 15:42:53
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,288
            CDSs (total)                      :: 8,175
            Genes (coding)                    :: 7,919
            CDSs (with protein)               :: 7,919
            Genes (RNA)                       :: 113
            rRNAs                             :: 11, 11, 11 (5S, 16S, 23S)
            complete rRNAs                    :: 11, 11, 11 (5S, 16S, 23S)
            tRNAs                             :: 77
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 256
            CDSs (without protein)            :: 256
            Pseudo Genes (ambiguous residues) :: 0 of 256
            Pseudo Genes (frameshifted)       :: 79 of 256
            Pseudo Genes (incomplete)         :: 220 of 256
            Pseudo Genes (internal stop)      :: 9 of 256
            Pseudo Genes (multiple problems)  :: 51 of 256
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:37:27
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 8186046
            Orig. end                         :: 8208494
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP115450.1.
            Bacteria and source DNA available from Mo Ping.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22448
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="37"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22448
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22448
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12448](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12448)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            220..558
                     /locus_tag="O1G21_RS36570"
                     /old_locus_tag="O1G21_36570"
     CDS             220..558
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O1G21_RS36570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O1G21_36570"
                     /product="hypothetical protein"
                     /protein_id="WP_270149864.1"
                     /transl_table=11
                     /translation="MGDGGTNEMTGGAADGAPNQAAEAATSVAGDENRGDGGPRELSRA
                     AAVGATVLAALCGCAALLAVFHWLGWAVPGVGWIVAKAGIKLAVGGFAGLAVGAAWLRT
                     RFRSLLRG"
     gene            complement(627..2165)
                     /locus_tag="O1G21_RS36575"
                     /old_locus_tag="O1G21_36575"
     CDS             complement(627..2165)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (123-476). E-value:
                     2.1e-18. Score: 58.8. Matches aSDomain:
                     nrpspksdomains_O1G21_RS36575_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004953346.1"
                     /locus_tag="O1G21_RS36575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_36575"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_270149866.1"
                     /sec_met_domain="PF00561 (E-value: 3.5e-21, bitscore: 74.8,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTTASRTRRAAAVLATAVLAGLALPATANADSGRNPGDAGRVPA
                     RYAGQKLDWQPCAGQPALDCATMAVPRDWHHPDAGPDLSIAVSRHRTADRAHRRGTLME
                     AAGGPGGQGLLRPMELVQGAPQVAAGYDIVSFDQRGVGRSTHAQCQTPEEFQEFLAGDW
                     RDQSPEAIDRTVANSRKLVSGCVEHSGDLLPYLTTEQTVRDMDLFRSLLGEEKISYYGA
                     SYATMIGAYYGTLFPHRVERMVLDSNIGFEGTWEQFELGQPMSFQRRFEQDFLPWMAAR
                     DATYHWGTTPEEVKAHWEQRRAALHGQPITDGSLTLGPNQLDNGTISAIYSEKAFPFLA
                     RALTALDDWQGADPAAKQTARQLFGQYLSPEFLAEYFSVTCGDTKWTKDMDTWIERGAE
                     NTARYPLLGARTLAFSSVCAAWPTDPAPKVKVTGAHLPPVLMLNSLHDPATYYEAALGA
                     HRALRGSRLVTVTSNGNHGQYPGSDPCVTDTVERYLLDGQVPEHDLTCPAAPAG"
     aSDomain        complement(738..1796)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_O1G21_RS36575_Abhydrolase_1.1"
                     /evalue="2.10E-18"
                     /label="O1G21_RS36575_Abhydrolase_1.1"
                     /locus_tag="O1G21_RS36575"
                     /protein_end="476"
                     /protein_start="123"
                     /score="58.8"
                     /tool="antismash"
                     /translation="APQVAAGYDIVSFDQRGVGRSTHAQCQTPEEFQEFLAGDWRDQSP
                     EAIDRTVANSRKLVSGCVEHSGDLLPYLTTEQTVRDMDLFRSLLGEEKISYYGASYATM
                     IGAYYGTLFPHRVERMVLDSNIGFEGTWEQFELGQPMSFQRRFEQDFLPWMAARDATYH
                     WGTTPEEVKAHWEQRRAALHGQPITDGSLTLGPNQLDNGTISAIYSEKAFPFLARALTA
                     LDDWQGADPAAKQTARQLFGQYLSPEFLAEYFSVTCGDTKWTKDMDTWIERGAENTARY
                     PLLGARTLAFSSVCAAWPTDPAPKVKVTGAHLPPVLMLNSLHDPATYYEAALGAHRALR
                     GSRLVTVTSNGNH"
     misc_feature    2230..2248
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.59"
                     /tool="antismash"
     gene            complement(2290..2928)
                     /locus_tag="O1G21_RS36580"
                     /old_locus_tag="O1G21_36580"
     CDS             complement(2290..2928)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018841191.1"
                     /locus_tag="O1G21_RS36580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_36580"
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_270149867.1"
                     /transl_table=11
                     /translation="MRITVFGATGNVGRRVVTEALARGHEVTAVVRDPAKPHGLPATVT
                     LAVGDASNPEDVARISAGQDVVITATRPAPGSEHELAAATRGLLTGLAGTGVRLLAVGG
                     AGSLTVPGTDGTILVESPGFPDEIRPIALACGEQLELYRADEKVDWTYLSPAALLEPGE
                     RTGRFRLGRDELLVDAEGNSAISMEDLAVVLLDEAEQPVHRRTRFTAGY"
     gene            complement(2985..3944)
                     /locus_tag="O1G21_RS36585"
                     /old_locus_tag="O1G21_36585"
     CDS             complement(2985..3944)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010046699.1"
                     /locus_tag="O1G21_RS36585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_36585"
                     /product="EamA family transporter"
                     /protein_id="WP_270149869.1"
                     /transl_table=11
                     /translation="MLSNRLAVVLVTALAPAVWGTTYAVTTEMLPPDRPLLAAVIRCLP
                     AGLLLIALTRTLPKGSWWWRALVLGALNIGGFQALLFIAAYRLPGGIAATVGAVQPLIT
                     AALSAALLGDRLTLRTVLSGIAGVAGVSLLVLRANARLDAIGLAAALGGAVVMAFGVVL
                     SKRWVSPAPLLATTGWQLTAGGLLLVPVTLLSEGAPPTHYTVDNVLGYAYLCLIGAALT
                     YAIWFRGLRALPPTSLSFLSLLSPVVATLVGWLTLGQDLSPLQALGAVVVLGSLIVAQT
                     QRARPLTTATAPAGPAPAGTAPADPAPGVRPSALHENA"
     misc_feature    complement(3930..3945)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.36"
                     /tool="antismash"
     misc_feature    3972..3986
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 19.43"
                     /tool="antismash"
     misc_feature    3992..4007
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     misc_feature    4002..4017
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 16.87"
                     /tool="antismash"
     gene            4056..4553
                     /locus_tag="O1G21_RS36590"
                     /old_locus_tag="O1G21_36590"
     CDS             4056..4553
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003986180.1"
                     /locus_tag="O1G21_RS36590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_36590"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_270149870.1"
                     /transl_table=11
                     /translation="MADHLDRVVAQWGAERPDLDVSPMEVFGRLKRLYRLVDAELNRTF
                     AEHGLDAPSFDVLATLKRSGPPYRLTPTGLMESAMVTSGAITQRLDRLEARGLVTRIRS
                     DQDRRSCYVELTPEGHALIDRALPDHVANEHRMLAGLDEAQRTALVQGMRALLANLGEV
                     SG"
     misc_feature    complement(4561..4572)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.15"
                     /tool="antismash"
     gene            4606..4791
                     /locus_tag="O1G21_RS36595"
                     /old_locus_tag="O1G21_36595"
     CDS             4606..4791
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O1G21_RS36595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O1G21_36595"
                     /product="hypothetical protein"
                     /protein_id="WP_270149872.1"
                     /transl_table=11
                     /translation="MDDPIWSALPAEARRAVDEHLTAGRHVHAIKAIRDASPERLPSIR
                     VYMDVIMDRKAELGLP"
     gene            complement(4824..5669)
                     /locus_tag="O1G21_RS36600"
                     /old_locus_tag="O1G21_36600"
     CDS             complement(4824..5669)
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (33-149). E-value: 1.4e-17. Score:
                     54.9. Matches aSDomain: nrpspksdomains_O1G21_RS36600_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003981620.1"
                     /locus_tag="O1G21_RS36600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_36600"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_270149873.1"
                     /transl_table=11
                     /translation="MTTETKPAPASHVPAPYVHGYSDAEAQRLGDQADTLAELLHAGTV
                     YPAGSRVLEAGCGVGAQTAHLLAASPGVLLTAADVSAESLAQARARIAAAAPTAQVVWH
                     HGDLHQLPFPDGAFDHVFLCFVLEHLPDPTAGLAALRRVLRPGGTITVIEGDHGSAFFH
                     PETPAARRTIDHLVRLQAGAGGDALLGRRLYPLLTAAGFADVAVRPRTVYADGGRPALV
                     DGFTRRTFVAMVEAVRAEALAAGLTTAEAFDQGIAELRRAAEPGGTFHYTFFKAVAVNP
                     "
     aSDomain        complement(5223..5570)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_O1G21_RS36600_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="1.40E-17"
                     /label="O1G21_RS36600_oMT.1"
                     /locus_tag="O1G21_RS36600"
                     /protein_end="149"
                     /protein_start="33"
                     /score="54.9"
                     /tool="antismash"
                     /translation="DTLAELLHAGTVYPAGSRVLEAGCGVGAQTAHLLAASPGVLLTAA
                     DVSAESLAQARARIAAAAPTAQVVWHHGDLHQLPFPDGAFDHVFLCFVLEHLPDPTAGL
                     AALRRVLRPGGT"
     gene            5698..7245
                     /locus_tag="O1G21_RS36605"
                     /old_locus_tag="O1G21_36605"
     CDS             5698..7245
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (183-469). E-value:
                     2.2e-14. Score: 45.3. Matches aSDomain:
                     nrpspksdomains_O1G21_RS36605_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018381481.1"
                     /locus_tag="O1G21_RS36605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_36605"
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_270149874.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.9e-12, bitscore:
                     45.3, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRSKGTEVDRSKEAGRSGEPGRPGETGADFLQLDAAEAPPGGLT
                     DWLARRLREAVADGRLPAGSRLPASRVLAAELGVSRGVVTDAYRRLAESGQLAGRGRGG
                     TVVVALTPAVPCEAPGNAPPGRPAPVLFRDDPDPDVFDHLRGTPARIDLTPGVPDLAAF
                     PRAAWLRAERAVLDGLVAHDLGYGDVRGTPALRQAVAHWLARNRGIRADPEEVLVVAGT
                     AQALALLGRSLGRAGITEVAVEDPGSLGARQHLAHWLAATPPVPVDSEGIRVDALRATG
                     APAVLLTPAHQYPTGVVLGGERRRELLRWAGEGGLVIEDDYDAEHRYDRPPLPALRAEL
                     PDRVCYAGSISKLLAPALRTGWLLVPPRLRGAVLDAKRFADLGNPVLPQLVLARLMESG
                     ELERHLRLLRRRHRRRRDAMIAAIRTHLPTATVHGAAAGLHLMLTLPEELACSDTELAT
                     LALARGVKVQPLSWHARLRCPPGLVLGYAAGSPGGITEGVAVLGELVRRVGRQPSSP"
     aSDomain        6247..7104
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_O1G21_RS36605_Aminotran_1_2.1"
                     /evalue="2.20E-14"
                     /label="O1G21_RS36605_Aminotran_1_2.1"
                     /locus_tag="O1G21_RS36605"
                     /protein_end="469"
                     /protein_start="183"
                     /score="45.3"
                     /tool="antismash"
                     /translation="LGYGDVRGTPALRQAVAHWLARNRGIRADPEEVLVVAGTAQALAL
                     LGRSLGRAGITEVAVEDPGSLGARQHLAHWLAATPPVPVDSEGIRVDALRATGAPAVLL
                     TPAHQYPTGVVLGGERRRELLRWAGEGGLVIEDDYDAEHRYDRPPLPALRAELPDRVCY
                     AGSISKLLAPALRTGWLLVPPRLRGAVLDAKRFADLGNPVLPQLVLARLMESGELERHL
                     RLLRRRHRRRRDAMIAAIRTHLPTATVHGAAAGLHLMLTLPEELACSDTELATLALARG
                     VKVQP"
     gene            complement(7268..7798)
                     /locus_tag="O1G21_RS41525"
     CDS             complement(7268..7798)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025391.5"
                     /locus_tag="O1G21_RS41525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4241 domain-containing protein"
                     /protein_id="WP_333493535.1"
                     /transl_table=11
                     /translation="MRHRSGGGRPGGDRPQRGSQHQQHRGQLGDLPERGHHASRVGNGI
                     RSASVPRDRPSGSPENAVTAPCAPRLGGCSNEEAVNALGPSGFRGRAVDSGFGCLFDST
                     ATASPGALLGEDGEVLRRAFARDRSGPGPVDLTEPGSGAGLVAFRTGFGEGLYPTWVAT
                     APAAGRSAWAPSS"
     gene            7691..8851
                     /locus_tag="O1G21_RS36615"
                     /old_locus_tag="O1G21_36615"
     CDS             7691..8851
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018553252.1"
                     /locus_tag="O1G21_RS36615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_36615"
                     /product="glycoside hydrolase family 3 N-terminal
                     domain-containing protein"
                     /protein_id="WP_270151458.1"
                     /transl_table=11
                     /translation="MAPFRQVAQLTSVLLVLGATLGPVPAGPAPAGSVTHRIGAHAERT
                     AAMTVRHQDSRQLAGRRIVLSYPGPTPPPETLDAIRKGRAAGVILFGENITSPEQLAQA
                     VGKLKQAAAEAPHPRPLLLMTDQEGGKVRRLPGAPELSARRTGTAPDPLAAAVDSGTGA
                     AGTLADAGLNVNLAPVLDVYDTPDNFIDHSERSYGQDPTRVGELGSAFLAAQQSQGVAA
                     TAKHFPGLGSAARDENTDARPVTLPVPLAQLRTRGEAPYRAAIAAGVRLVMASWAVYPA
                     LDPDRPAGFSPTVIQGELRDRLGFRGVTVTDALEADALTPYGPAGPRAVAAAAAGMDLI
                     LCSARDPQQGEDATAALAAALDSGSLDREAFAEAVARVDALRDGLG"
     gene            9353..9697
                     /locus_tag="O1G21_RS36620"
                     /old_locus_tag="O1G21_36620"
     CDS             9353..9697
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008736324.1"
                     /locus_tag="O1G21_RS36620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_36620"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_270149876.1"
                     /transl_table=11
                     /translation="MPVPLYQAKAEFFRTLGHPVRIRVLELLQDGPRPVRELLAEIEVE
                     PSNLSQQLAVLRRTQLVTATREGNTVVYALSTPDVAELLRAARRILTELITDQGALLTE
                     LRAPGGRSPR"
     gene            9825..9983
                     /locus_tag="O1G21_RS36625"
                     /old_locus_tag="O1G21_36625"
     CDS             9825..9983
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040000.4"
                     /locus_tag="O1G21_RS36625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_36625"
                     /product="DUF6126 family protein"
                     /protein_id="WP_270149878.1"
                     /transl_table=11
                     /translation="MSDSADSPVKGDGTSEEKRRRKAMLVRAGIYIFATHLFAGFVLLL
                     FALGGRK"
     gene            complement(10001..12448)
                     /locus_tag="O1G21_RS36630"
                     /old_locus_tag="O1G21_36630"
     CDS             complement(10001..12448)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012296.5"
                     /locus_tag="O1G21_RS36630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_36630"
                     /product="cytochrome P450"
                     /protein_id="WP_270149879.1"
                     /sec_met_domain="p450 (E-value: 3.5e-73, bitscore: 245.7,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="T1TS (E-value: 3.4e-49, bitscore: 167.3,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALPTNALLAETRKRIVPPRTTPPPVPTVRAAVPPLAPGALPGLG
                     HAAALLRDPLGFLGSLARLGGVVRIRLGPRTVCVVTDARLVHTLLVALAHDCPRGAVQD
                     TLKTAFGDGLLMSEGQAHRDRRRIIQPAFGPDRMAGYLAVMHQVTEERAGRWRSGQVLD
                     VAKEMNHLALEIVTRSLFGARLSEDATLAFHRALPDLVKGQIVQSLYPHPAFARLPLPV
                     NRRFDAAVRVLNQVVDQAVNGRAGKARSAQRGNTLPALLRAATDPATGRALTEADVRSE
                     AITMFGAGTETVSTTLTWLLDELLRHPEVEARVLAELDEHLPAGATPTPEALSRLTYTR
                     SVTQEVVRLHAPNAFLMRTAQVPVDLGPYRIPAGTELLYSLTALHRDPVRYDEPLSFRP
                     ERWQDGGGLGRPSFLPFGAGKHKCIGEAFAWAELTVAAAAILRRWRPVAVPGARAREVV
                     WTTVQAQGLKVRLAPRTPTTVATDEGPAATEPDRPLPARCPFTGTAATPVPAPRPPAEL
                     RAAADRHADWAVRHGLLAPAELPGYQAYGLHELIGHAFPRARGTELDLLVDVLGWFTVL
                     DDRFDGPPGRRPAEAHALVDPLISALDGDARPDTPDDRLLTAWRELWHRQSESTSAAWR
                     ARAAREWRACLATFPAEAEHRARGTVPALGLGLTDTMRLRRHGSCLYPFMNILERVHGA
                     DAPAALHAEPALHRLRANTADAATLINDLYSLEREERQSAAAFNTVLTLQRVRGCTRSR
                     AVRAVRARVARLRQENEELRRDLGRRHPAGRWYLDGTRELVAGVQAWTSTSDRYLVPGE
                     RGR"
     gene            12827..13276
                     /locus_tag="O1G21_RS36635"
                     /old_locus_tag="O1G21_36635"
     CDS             12827..13276
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O1G21_RS36635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O1G21_36635"
                     /product="hypothetical protein"
                     /protein_id="WP_270149880.1"
                     /transl_table=11
                     /translation="MDCDGEVMLTVRIAAAERALLRDLARGHGGDVSGVAVDGLLEVIP
                     ALSDDGSVLPLLRVLARPAPCAVTLWLPAPVADLLPLLGERLVRTGGPATGSASAALSA
                     ALRLWLAGDRAVLAAGLARLHGGCGATGRAARSAVGGVARIEVAA"
     misc_feature    complement(13355..13370)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 21.01"
                     /tool="antismash"
     misc_feature    13621..13639
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.43"
                     /tool="antismash"
     misc_feature    13628..13642
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.72"
                     /tool="antismash"
     misc_feature    13635..13651
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 15.74"
                     /tool="antismash"
     gene            13752..15962
                     /locus_tag="O1G21_RS36640"
                     /old_locus_tag="O1G21_36640"
     CDS             13752..15962
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012859.5"
                     /locus_tag="O1G21_RS36640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_36640"
                     /product="RICIN domain-containing protein"
                     /protein_id="WP_270149881.1"
                     /transl_table=11
                     /translation="MGHRSSELRRRRRRRLTRRSALVAVAVAAGLVAGTLGLRTVLEPG
                     AVRATVTAADAPVDAVADDGGPGETGTAEGATKAPAPKRDEKVAPPKAIPKDQPERGLV
                     YAGLNLPTSDRCGNMLEVTGSTQCSHGPDAPPKDVDMRKDVPPVAAPAAQAPALTPAAG
                     SQPPAAADLLKGGAPVLDATQKALLGGSAAASAPAAASGTAAEPQGAAAPAAGSGLVCE
                     GDGSSGNRVQVVYVHTPGNDRYAQYLSSFKKWAADVDVIYNASAAETGGVRHVRFVTEP
                     DCTASVLNVQISDAEIQDFNASNRALAAQGFNRKDRKYMMFTDAKVYCGIGTFAGDERA
                     GQDNLSNFGPSYGRTDAGCWSGSTAAHELGHNLGAVNNSAPNSSKAGHCTDEWDIMCYS
                     DAPYYPQMRTVCPDRAHDDRLDCNHDDYYNTNPAPGSYLATHWNVANNRFLIAGNGTGP
                     NPTPTPTPTSSPTATGTPTRTPSPSPTPTGSPTATPTGSPSPTATPPTGSTGPDVTVSQ
                     ITQNSVMLSWNPVPSAAGYDVQLNGQTIGTVRSTVVGVVRLAPGTGYTVAVAVRDAAGT
                     VGKPGRQASFHTLADAGRPQPGTHYTMVNGLTGQAADLWGSSMNDGTVAIGYQRTGYAN
                     QKWSFEDAGNGAVRIKSVRSGKCLQLGGTPVAGQYVAQQPCSDAGAQKWQLAAGDGGFT
                     LAADGSTLVLGLSDRWYYGGWLLELQQPNGRPYQNWSLVKTS"
     gene            16016..16687
                     /locus_tag="O1G21_RS36645"
                     /old_locus_tag="O1G21_36645"
     CDS             16016..16687
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O1G21_RS36645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O1G21_36645"
                     /product="hypothetical protein"
                     /protein_id="WP_270149883.1"
                     /transl_table=11
                     /translation="MAAAPGAAAPRTLTVSARGTPVMVIRTRPLLAALALAAAAVLPAA
                     APAAAHGDTVHLEVAGQRNGRISAVATWENDHDPVTEDFAGTLSATAADGRTIGPWRLV
                     AVPDRPGTYTTRELLPAGHWKVVVDCAFPSLGHGERELDVEAAAISDPAPMGAAAGAAA
                     PAAPETGAPAAAMTATAAAPVHGTTDDATTWAATATATATAVVVLVAVGFRLRARARAR
                     R"
     gene            16823..17839
                     /gene="galE"
                     /locus_tag="O1G21_RS36650"
                     /old_locus_tag="O1G21_36650"
     CDS             16823..17839
                     /EC_number="5.1.3.2"
                     /GO_function="GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (44-160). E-value: 6e-09.
                     Score: 27.3. Matches aSDomain:
                     nrpspksdomains_O1G21_RS36650_NAD_binding_4.1"
                     /codon_start=1
                     /gene="galE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891305.1"
                     /locus_tag="O1G21_RS36650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_36650"
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="WP_270149884.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 6.5e-09, bitscore:
                     34.1, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 2.2e-10,
                     bitscore: 38.9, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKVLITGGAGFIGSTVASVLLDRGITPVVLDDLSKGRAEFVRNR
                     VFYQGDIADAALLERIFTEHPDIDATVHCAARIIVPESVAKPLFYYRENVAKTVELLDA
                     LQRHGCTRVVFSSSASIYAPTPDAKVDESSAVEANSPYARTKLMMEQVLQDWTRGEGAE
                     QQRVIALRYFNPIGADSQLRTGLQNLNPSHALGKLIEAHTYGTPFTVTGVDWPTRDGSG
                     IRDYIHVQDLAEAHVAALLRFDEVIAPDAADRYRAINVGTGEGTTVRELVAAFEQAVGT
                     ELDVREAGPRPGDVIGCYASVDAARDLLGWAPQRTLAEGVADALAWRTKWAAELGVS"
     CDS_motif       16835..16897
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_O1G21_RS36650_0001"
                     /evalue="2.30E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="O1G21_RS36650"
                     /protein_end="25"
                     /protein_start="4"
                     /score="10.6"
                     /tool="antismash"
                     /translation="LITGGAGFIGSTVASVLLDRG"
     misc_feature    complement(16849..16865)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 22.11"
                     /tool="antismash"
     aSDomain        16955..17302
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_O1G21_RS36650_NAD_binding_4.1"
                     /evalue="6.00E-09"
                     /label="O1G21_RS36650_NAD_binding_4.1"
                     /locus_tag="O1G21_RS36650"
                     /protein_end="160"
                     /protein_start="44"
                     /score="27.3"
                     /tool="antismash"
                     /translation="RVFYQGDIADAALLERIFTEHPDIDATVHCAARIIVPESVAKPLF
                     YYRENVAKTVELLDALQRHGCTRVVFSSSASIYAPTPDAKVDESSAVEANSPYARTKLM
                     MEQVLQDWTRGE"
     gene            complement(17852..18541)
                     /locus_tag="O1G21_RS36655"
                     /old_locus_tag="O1G21_36655"
     CDS             complement(17852..18541)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018567767.1"
                     /locus_tag="O1G21_RS36655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_36655"
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_270149885.1"
                     /transl_table=11
                     /translation="MSEEQKGSRWGRWIVIGVLAAAGWGIVRGGGHEPATSSAAPSSSP
                     STTAAAPSAASPGASSASPSKPSGSYEPADYAAPVRQYAGEAGVNPQLLMAILYNEAYK
                     PHDPEFERAWQRNKPDAAFGIANMHRAAFDDTKPGRPFASRRWEELPDDRNLAIQAAAW
                     HLHDLAGQLPARVSAPLDKDELLALGYNAGAGNMLAFARGVKIGPQAQSYLDRLHDNWA
                     RSGEAVR"
     gene            complement(18625..18831)
                     /locus_tag="O1G21_RS36660"
                     /old_locus_tag="O1G21_36660"
     CDS             complement(18625..18831)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016471586.1"
                     /locus_tag="O1G21_RS36660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_36660"
                     /product="antitoxin"
                     /protein_id="WP_270149886.1"
                     /transl_table=11
                     /translation="MFESLKNLADKATDLAREHSDVLGQGLEKVGEVIDDRTDGKYSGQ
                     IDTGVEKAKDFLRNLDGEQKTAE"
     misc_feature    complement(18907..18922)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.83"
                     /tool="antismash"
     misc_feature    complement(18909..18929)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.27"
                     /tool="antismash"
     gene            19111..19683
                     /locus_tag="O1G21_RS36665"
                     /old_locus_tag="O1G21_36665"
     CDS             19111..19683
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF042451.3"
                     /locus_tag="O1G21_RS36665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_36665"
                     /product="DUF6542 domain-containing protein"
                     /protein_id="WP_270149887.1"
                     /transl_table=11
                     /translation="MAGQRARTSYQDAGPRTEDPAVPAQRSRAAGGDADPAREARAQRG
                     GASRRRQQARRRGGPLAALTAVGLPLVGGIADELSGPGAGILFAVGAVLGTGLAALLCS
                     RAGRWWVVTAAPVVVLLTASGVEYLCNPDKYQGKGLGTGAVRWMVGAFPVMAEAVAVVL
                     LVIVVRAVLERRRPARAGAPSGRGRRG"
     gene            19676..21271
                     /locus_tag="O1G21_RS36670"
                     /old_locus_tag="O1G21_36670"
     CDS             19676..21271
                     /GO_process="GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004944133.1"
                     /locus_tag="O1G21_RS36670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_36670"
                     /product="LCP family protein"
                     /protein_id="WP_270149889.1"
                     /transl_table=11
                     /translation="MAELSNRPRGRVPGRGPAPLTVAGRTLACAVSVAVLGASGFTWYE
                     YRSLDDGVFKSTALADAKKNAPPHLDKSVNLLLIGLDSRKDMDGNDLPKQFVEDELHAG
                     SSEIGGYNTNALIVLHIPANGGKVTALSVPRDDYVQTVGADGRMHKIKEAYGIAKEAAE
                     AKLAGKALSRAELERQSREAGRSATIQTVQSFLDVPIDHFAEVNLIGFYDIAKAVEPIQ
                     VCLNHPVDDPIIARTATHEGGGTGLKLPAGISSLDAAQALSFVRQRHHLTNGDLDRTHR
                     QQAFISSVEYRLKQQGILNDFGQMQKLFEVVKKDVVIDNEWNVLDFAQQAPNLTGGNVE
                     FNTLPITGFKTIGGQEVNTVNPDLIKRIVRQLFNHEQAPAVPATAPGNAPSETATSTPS
                     PSAAPKSVVDVNAAAGAGAAATESKALVELGYQAGRIGEAPARTRATAVTYGSGAKADA
                     QAVAARYGVTAVPSSAVAAGHVLVTLAATRTPTPTPTAPSAGASAPADGSADPAAGLPM
                     QGPAVKAGGIPCVD"
     gene            complement(21296..21667)
                     /locus_tag="O1G21_RS36675"
                     /old_locus_tag="O1G21_36675"
     CDS             complement(21296..21667)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020137311.1"
                     /locus_tag="O1G21_RS36675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_36675"
                     /product="hypothetical protein"
                     /protein_id="WP_270149890.1"
                     /transl_table=11
                     /translation="MTGHPLVREVFPDLVHELVALLEQEGEPELAVHARDLRLVADCGC
                     GDDFCQSFHTEPHRAGQPYGPGHRCVPLLPAKGTLFLDVVDGRIMYVEVLGHEPLRDLR
                     VHQPEQPDRPGRPDDWPGR"
ORIGIN
        1 gggcgttcgg ccgcccgcgc actggaggag gcggccgcct ggtgccggca ggcccccgag
       61 gccgaagtgc actcgctcgc ctgggcccgg gtgccgggcc accgccacga cgtcttcgag
      121 taccgcgtca ccatggccgt cagcttcccc gacgaggaga ccggcgagca cctcggcgac
      181 acccaccact cctgccgctg aagccgtatc atcaccccca tgggtgatgg gggtacgaac
      241 gagatgaccg gcggcgcggc ggacggcgca cccaaccagg ccgcagaggc cgccacttcg
      301 gtcgccggcg acgagaacag gggcgatggc ggcccgcgcg agctgtcccg ggccgccgcc
      361 gtcggtgcca ccgtgctggc cgccctctgc ggctgcgcgg cgctgctggc cgtgttccac
      421 tggctgggct gggccgtccc cggggtcggc tggatcgtgg ccaaggccgg gatcaagctg
      481 gccgtgggcg gcttcgccgg actcgccgtc ggcgccgcct ggctgcgcac caggttccgg
      541 tcacttctgc gcggttgacg agctgcggtt gacgagctgc ggttgacgag ccgcggttga
      601 cgagccgcgg ttgacgggcc ggtggctcaa ccggccggtg cggccgggca ggtgaggtcg
      661 tgctcgggca cctgcccgtc cagcaggtag cgctcgacgg tgtcggtgac gcacgggtcg
      721 gagcccgggt actggccgtg gttgccgttg ctggtgacgg tgaccagcct cgagccgcgc
      781 agcgcgcggt gcgcaccgag cgcggcctcg tagtacgtgg ccgggtcgtg cagcgagttg
      841 agcatcagca ccggtggcag gtgcgcgccg gtgaccttga ccttcggcgc cgggtccgtc
      901 ggccaggccg cgcagaccga gctgaaggcg agggtgcggg caccgagcag tgggtagcgg
      961 gcggtgttct ccgcgccgcg ctcgatccag gtgtccatgt ccttggtcca cttggtgtcc
     1021 ccgcacgtca ccgagaagta ctcggcgagg aactccgggc tgaggtactg gccgaacagc
     1081 tggcgggcgg tctgcttggc ggccggatcg gcgccctgcc agtcgtccag cgcggtcagc
     1141 gcgcgggcca ggaacggaaa ggccttctcg ctgtagatcg cgctgatggt gccgttgtcc
     1201 agctggttcg ggccgagcgt caacgagccg tcggtgatgg gctggccgtg cagcgcggcg
     1261 cgccgctgct cccagtgcgc cttgacctcc tccggcgtcg tgccccagtg gtaggtggcg
     1321 tcccgggcgg ccatccaggg caggaagtcc tgctcgaacc ggcgctggaa gctcatcggc
     1381 tggcccagct cgaactgctc ccaggtgccc tcgaagccga tgttgctgtc cagcaccatc
     1441 cgctcgaccc ggtgcgggaa tagcgtgccg tagtaggcgc cgatcatggt ggcgtaggag
     1501 gcgccgtagt agctgatctt ctcctcgccg agcagcgagc ggaacaggtc catgtcccgg
     1561 acggtctgct cggtggtcag gtagggcagc agatcgccgc tgtgctccac gcaaccggac
     1621 accagcttgc gggagttggc gacggtccgg tcgatcgcct cgggggactg gtcgcgccag
     1681 tccccggcca ggaactcctg gaactcctcc ggggtctggc actgggcgtg ggtgctgcgc
     1741 ccgacgccgc gctggtcgaa gctgacgatg tcgtacccgg cggccacctg gggggcgccc
     1801 tggacgagct ccatcggccg cagcaggccc tgtccgcccg gaccgcccgc ggcctccatc
     1861 agcgtccctc gccggtgcgc ccggtcggcg gtgcggtgcc gggagacggc gatggacaga
     1921 tccggcccgg cgtcggggtg gtgccagtcg cgcgggacgg ccatggtggc gcagtcgagc
     1981 gccggctgcc ccgcgcaggg ctgccagtcg agcttctggc cggcgtagcg ggcgggtacg
     2041 cgcccggcgt cgcccgggtt gcggccggag tcggcgttcg ccgtggcggg cagggcgagg
     2101 ccggcgagga ccgcggtggc gaggacggcg gccgcgcggc gggtgcggga tgcggtggtg
     2161 ttcacgggaa cgatcgtgtc cgacgcgaca cctgacgcgc gatgatgctg gacaccgtct
     2221 ccggggtggt gctggataca cctccggggg gcatccagca ccacggctgt caggtgccgt
     2281 caggaccggt cagtagcccg cggtgaagcg ggtgcgccgg tggacgggct gctcggcctc
     2341 gtcgagcagc acgacggcga ggtcctccat cgagatcgcc gagttgccct cggcgtcgac
     2401 cagcagctcg tcccggccga gccggaagcg gccggtgcgc tccccgggct cgagcagggc
     2461 ggccgggctc aggtacgtcc agtcgacctt ctcgtcggcg cggtagagct ccagctgctc
     2521 gccgcaggcc agcgcgatcg gccggatctc gtcggggaag ccgggggact ccaccaggat
     2581 cgtgccgtcg gtgccgggca cggtcaggct gcctgcgccg ccgaccgcga gcaggcgcac
     2641 gcccgtaccg gccaggccgg tcagcaggcc ccgggtggcg gcggccagtt cgtgctcgct
     2701 gccgggcgcc ggacgggtgg cggtgatcac cacgtcctgc ccggcggaga tccgggcgac
     2761 gtcctcgggg ttgctcgcgt cgcctacggc gagggtgacg gtggcgggca ggccgtgcgg
     2821 cttggccggg tcgcggacga cggcggtgac ctcgtggccg cgggcgagcg cctcggtcac
     2881 gacccgccgg ccgacgttgc cagtggcgcc gaacacggtg atacgcatga aggtttctcc
     2941 ttggtttctt ggagcgggac tgcggtggag cggttggtgt ggggtcaggc gttctcgtgc
     3001 agcgcgctcg gccggacgcc gggtgccggg tccgcgggtg ccgtgcccgc cggagcgggg
     3061 ccggcgggcg ccgtggccgt ggtaaggggc cgggcccgct gggtctgggc gacgatcagc
     3121 gaaccgagca cgaccaccgc gcccagcgcc tgcagcggac tgaggtcctg tccgagcgtc
     3181 agccagccga ccagcgtggc caccaccggg ctgagcaggg agagaaagga gagcgaggtc
     3241 ggcggcagcg cgcgcagtcc gcggaaccag atcgcgtagg tgagggccgc gccgatcagg
     3301 cagaggtagg cgtagccgag cacgttgtcg acggtgtagt gggtgggcgg ggcgccctcg
     3361 ctcagcaggg tgaccggcac cagcagcaga ccgccggcgg tgagctgcca gccggtggtg
     3421 gcgagcagtg gcgcggggga gacccagcgc ttggagagca ccaccccgaa ggccatcacc
     3481 accgcgccgc cgagcgcggc ggccagcccg atcgcgtcca gccgggcgtt ggcgcgcagc
     3541 accagcaggc tgacgcccgc cacgcccgcg atgccggaca gcacggtgcg cagggtgagc
     3601 cggtcaccga gcagggcggc cgagagggcg gcggtgatca gcggctggac ggcgccgacg
     3661 gtggccgcga tcccgccggg caggcggtag gcggcgatga acagcagggc ctggaagccg
     3721 ccgatgttga gcgcgccgag gacgagcgcg cgccaccacc agctgccctt cggcagggtg
     3781 cgggtgaggg cgatcagcag cagtccggcg ggcaggcagc ggatgacggc ggcgaggagc
     3841 ggacggtcgg gcgggagcat ctcggtggtg acggcgtagg tcgtccccca gacggcgggg
     3901 gcgagggccg tcaccagcac gacggcgagg cgattgctta gcactaagcc aatgtatctc
     3961 agcgctaagg tatctttcag tgaattccac cggtgacgtg gctcacagtt acctcaccgc
     4021 taaggaatcg tcccggcgtc gcctaccctg aacccgtggc agatcatctc gaccgtgtcg
     4081 tcgcgcaatg gggcgccgag cgccctgacc tggacgtctc cccgatggag gtgttcggcc
     4141 ggctcaaacg cctctaccgc ctggtggacg ccgagctcaa ccgcaccttc gccgagcacg
     4201 gcctggatgc cccctccttc gacgtcctgg ccaccctcaa gcgcagcgga ccgccgtacc
     4261 gcctcacccc caccggcctg atggagtccg ccatggtcac ctccggcgcg atcacccagc
     4321 gcctggaccg actggaggcc cgcggcctgg tcacccgcat ccgcagcgac caggaccgcc
     4381 gcagctgcta cgtcgagctc acccccgagg gccacgccct gatcgaccgc gcgctgcccg
     4441 accacgtcgc caacgagcac cgcatgctgg ccggcctcga cgaggcgcag cggaccgcgc
     4501 tcgtccaggg gatgcgcgcc ctgctcgcga acctcgggga ggtctccggc tgaccgctga
     4561 ttaatcgttt gccgggcccg gccgccgtcc tcttggatgg cggccatgga cgatccgatc
     4621 tggtccgcac tgcccgccga ggcccggcgc gcggtggacg aacacctcac cgcggggcgc
     4681 cacgtccacg cgatcaaggc catccgcgac gcgtcaccgg agcggctgcc cagcatccgg
     4741 gtctacatgg acgtgatcat ggaccggaag gcggaactcg gcctgccgta gggcggtccg
     4801 acctcgccgc tggatcctgc cgactacggg ttgaccgcca ccgccttgaa gaaggtgtag
     4861 tggaacgtcc cgcccggctc ggccgcccgg cgcagttcgg cgatgccctg gtcgaaggcc
     4921 tcggcggtgg tcagaccggc ggccagggcc tccgcccgga cggcctccac catcgcgacg
     4981 aaggtccgcc gggtgaagcc gtccaccagc gccgggcggc ctccgtcggc gtagaccgta
     5041 cggggacgga cggccacgtc cgcgaagccg gccgccgtca gcagcgggta cagccgacgg
     5101 cccagcaggg cgtcgccgcc cgccccggcc tggagccgca ccaggtggtc gatggtgcgg
     5161 cgggcggccg gggtctccgg gtggaagaag gccgagccgt ggtcgccctc gatcaccgtg
     5221 atcgtcccgc ccggccgcag cacccgccgc aacgcagcca ggccggctgt cgggtcgggc
     5281 aggtgctcca gcacgaagca caggaagacg tggtcgaacg cgccgtccgg gaagggcagt
     5341 tggtgcaggt cgccgtggtg ccagacgacc tgggcggtcg gtgccgcggc ggcgatccgg
     5401 gcccgggcct gcgccagcga ctcggcggag acgtccgccg ccgtcagcag cacgccgggg
     5461 ctggcggcca gcaggtgcgc cgtctgtgcc ccgaccccgc agcccgcctc cagcacccgg
     5521 ctgcccgccg ggtagaccgt gcccgcgtgc agcagctcgg cgagggtgtc ggcctggtcg
     5581 ccgaggcgct gcgcctcggc gtcggagtag ccgtggacgt agggggcggg gacgtgggag
     5641 gcaggggcgg gtttggtctc ggtggtcatg gctcaaccct cgcgccacta tggaccggtg
     5701 aacaggtcca aaggcactga ggtcgacagg tccaaagagg ccgggaggtc cggggaaccg
     5761 ggcaggcccg gggagaccgg ggcggacttc ctccagctcg acgccgccga ggccccgccc
     5821 ggcggcctca ccgactggct ggcccgccgg ctgcgcgagg ccgtcgccga cggccgtctc
     5881 ccggcgggca gccgactgcc cgccagccgg gtactggcgg ccgaactcgg cgtctcccga
     5941 ggggtggtga ccgacgccta ccggcggctc gccgagtcgg gccagctcgc cgggcggggc
     6001 aggggtggca ccgtcgtggt cgccctgaca cccgccgtac cgtgcgaggc cccggggaac
     6061 gccccgccgg gtcgcccggc gcccgtgctg ttccgggacg accccgaccc cgacgtgttc
     6121 gaccacctgc gcggcacccc cgcccggatc gacctcactc ccggcgtgcc cgacctcgcc
     6181 gccttccccc gcgccgcctg gctgcgggcc gaacgggcag tcctcgacgg cctggtcgcc
     6241 catgacctcg gctacggcga cgtccgcggc acccccgccc tacggcaggc cgtcgcccac
     6301 tggctggccc gcaaccgggg catccgggcc gatcccgagg aggtgctggt cgtcgccggg
     6361 acggcccagg cgctcgccct gctcggccgc tccctcggac gggcgggcat caccgaggtc
     6421 gccgtcgagg acccgggctc gctcggcgcc cgccagcacc tcgcccactg gctcgccgcc
     6481 accccgcccg tcccggtcga ctccgagggc atccgggtcg acgcgctgcg cgccaccggt
     6541 gcccccgccg tcctgctcac ccccgcccac cagtacccga ccggcgtcgt cctcggcggt
     6601 gagcggcgcc gcgaactgct gcgctgggca ggcgaaggag ggctggtcat cgaggacgac
     6661 tacgacgccg aacaccgcta cgaccgcccg cccctccccg ccctgcgggc cgaactgccc
     6721 gaccgggtct gttacgcggg cagcatctcc aaactgctcg cccccgccct gcgcaccggc
     6781 tggctgctgg tgcccccgcg actgcgcggg gccgtgctcg acgccaagcg cttcgccgat
     6841 ctcggcaacc cggtgctgcc ccaactggtg ctcgcccgac tgatggagtc cggcgaactc
     6901 gagcgccacc tacggctgtt gcgccgccgc caccgccgcc gccgggacgc gatgatcgcc
     6961 gccatccgca cccacctgcc caccgccacg gtgcacggcg cggccgccgg actgcacctg
     7021 atgctcaccc tgccggagga actcgcttgc agtgacaccg agttggccac cctggccctc
     7081 gcccgcgggg tcaaggtcca gcccttgtcc tggcacgccc ggctccggtg cccgcccggt
     7141 ctggtcctcg gctacgcggc cggctcaccg ggcgggatca ccgaaggggt ggccgtcctg
     7201 ggggagttgg tgcggcgcgt ggggcgtcag ccgtcctcgc cgtagtcacg gcccgccgcc
     7261 gggacgatca cgaactcggt gcccaggccg accgtccggc cgccggcgcc gtggccaccc
     7321 aggtcgggta gagcccctcg ccgaagccgg tgcggaacgc gaccaggccc gcgccggagc
     7381 ccggctcggt gaggtcgacc gggcccggcc cgctccggtc ccgcgcgaag gcccgcctga
     7441 gcacctcgcc gtcctcgccc agcagcgcgc ccggcgaagc cgtggccgtg ctgtcgaaga
     7501 ggcaaccgaa gccgctgtcc acggcacggc cgcggaaccc ggaagggccg agcgcgttca
     7561 ccgcctcctc gttcgaacat ccgcccaacc taggagcgca tggggcggtc acggcgtttt
     7621 ccgggctgcc ggacggccgg tccctgggta cgctggcgga ccgtatgccg ttgccgaccc
     7681 tggaggcgtg atggccccgt tccggcaggt cgcccagttg acctcggtgc tgctggtgct
     7741 gggagccacg ctggggccgg tccccgccgg gcctgccccc gccggatcgg tgacgcaccg
     7801 catcggcgcc cacgccgaga ggaccgcagc gatgaccgtc cggcaccagg actcccggca
     7861 gctcgcgggg cgtcggatcg tgctctccta cccgggcccg accccgccgc ccgagacgct
     7921 ggacgcgatc cggaagggtc gggccgccgg ggtcattctg ttcggtgaga acatcaccag
     7981 tcctgaacaa ctcgcccaag cagtcgggaa gttgaagcag gcagccgccg aggctccgca
     8041 cccgcgcccg ctgctgctga tgaccgacca ggagggcggc aaggtccgcc ggctgcccgg
     8101 cgcacccgaa ctctccgccc ggcgcaccgg aacggccccg gacccgctcg ccgccgccgt
     8161 ggactccggc accggcgccg ccgggaccct cgccgacgcc gggctgaacg tcaacctcgc
     8221 cccggtgctc gacgtctacg acaccccgga caacttcatc gaccactccg agcgctccta
     8281 cggccaggac cccacccggg tgggcgaact gggcagcgcg ttcctcgccg cccagcagag
     8341 ccagggcgtg gcggccaccg ccaagcactt ccccggcctc ggctcagccg cccgcgacga
     8401 gaacaccgat gcccgccccg tcaccctccc cgtcccgctc gcccagctgc gcacccgcgg
     8461 cgaagccccg taccgcgccg ccatcgccgc gggcgtgcgc ctggtgatgg cctcctgggc
     8521 cgtctatccg gccctcgacc ccgaccgtcc ggccggattc tcgcccaccg tgatccaggg
     8581 cgagctccgc gaccgcctcg gcttccgggg cgtcaccgtc accgacgccc tcgaagccga
     8641 cgccctcacc ccgtacggac ccgccggccc ccgcgccgtc gccgccgcgg cagccggcat
     8701 ggacctcatc ctctgctccg cccgcgaccc ccagcagggc gaggacgcca ccgccgccct
     8761 ggcggccgcc ctcgactccg gcagcctcga ccgcgaggcc ttcgccgaag ccgtggcccg
     8821 ggtggacgcc ctgcgggacg gcctgggctg accgggcggc agggccgagc tgtcccgcac
     8881 cagcccaggt cgcctcgagg agaggcgtcc ggctccctgg ggaccgcctg cccgtcgggc
     8941 ccgccggaag ccgggcggag cggcgccggg caggtcatcg gcacaggagg ccgggcgcgg
     9001 gcccggtgtc ggtcccgacc ggcaaagtgc cgcccatgga cgcgctcctc ggtcgggatc
     9061 cggcggatct cggaaccgag caggggctcg ggtgccggtg cgacggccag gagggcggcg
     9121 acggcgatca gcgccgcggt ggcggtgcgg aggcgacgtc ctttgaccgg ggaatgagat
     9181 gtcatgtgtg gaacaccttg ctgaacggga tgtggccgcc cgtgtgggag ttgtcacctt
     9241 ccgctgtgac gacttgaaga aatcttcatc tgtcgcgatg atgcctgtcg gccgcgcgtg
     9301 aacccgcccg gccctatgac cacccagccg gattcgaggg agggaacggg cgatgccggt
     9361 cccgctgtac caggccaagg cggagttctt ccgcactctc ggccacccgg tccggatccg
     9421 ggtcctggag ctgctccagg acggaccccg accggtgcgc gagctgctgg cggagatcga
     9481 ggtcgagccg tccaacctct cccagcagct cgcggtgctg cgccgcaccc agctggtcac
     9541 ggccacccgc gagggcaaca cggtggtgta cgcgctcagc actccggacg tcgccgagct
     9601 gctgcgcgcg gcgcgccgga tcctcaccga gttgatcacc gaccagggcg cgctgctcac
     9661 cgagctgcgc gctcccggcg gccggtctcc ccgctgagcc cggaaccagc agtccgcagc
     9721 ctgcagcccg aagcccgcga cctgcggccc ggaaggcgca gtccgaagct cgcggccgtg
     9781 cccaccggcc cgcgcccgcg tccgactccg aggagagccg caccatgagc gacagcgccg
     9841 acagcccggt gaagggcgac ggtacgagcg aggagaagcg ccgccgcaag gcgatgctgg
     9901 tccgcgcggg gatctacatc ttcgccaccc acctgttcgc gggcttcgtc ctgttgctgt
     9961 tcgcgctcgg cggccgcaag tagcgcggcc cccgggggaa tcaacgcccc cgctcgcccg
    10021 gtaccaggta gcggtcactg gtgctggtcc aggcctggac gccggcgacc agttcccggg
    10081 tgccgtccag gtaccagcgc cccgccgggt gccggcggcc caggtcgcgg cgcagttcct
    10141 cgttctcctg gcgcagccgg gcgacccggg cgcggaccgc tcggacggcc cggctgcggg
    10201 tgcagccgcg gacccgctgc agggtcagga cggtgttgaa ggcggccgcg ctctgccgtt
    10261 cctcccgctc cagcgagtag aggtcgttga tcagcgtcgc ggcgtcggcg gtgttggccc
    10321 gcaggcggtg cagtgcgggc tccgcgtgca gggcggcggg ggcgtcggcg ccgtggaccc
    10381 gttccagtat gttcatgaag gggtagaggc agctgccgtg gcggcgcagc cgcatggtgt
    10441 ccgtgaggcc gaggccgagg gcggggacgg tgccgcgggc gcggtgctcg gcctcggcgg
    10501 ggaaggtggc caggcaggct cgccactcgc gggccgccct ggcgcgccag gccgcggagg
    10561 tcgactcgct ctggcggtgc cagagttccc gccaggcggt gagtagccgg tcgtccgggg
    10621 tgtccgggcg cgcgtcgccg tcgagggcgg agatcagcgg gtcgaccagc gcgtgggcct
    10681 ccgcgggacg gcgtccgggc ggcccgtcga agcggtcgtc caggacggtg aaccagccca
    10741 gtacgtcgac cagcaggtcc agttcggtgc cccgggcgcg cgggaaggcg tggccgatca
    10801 gctcgtgcag cccgtaggcc tggtagccgg gcagctcggc cggggcgagc aggccgtggc
    10861 ggaccgccca gtcggcgtgc cggtcggcgg cggcgcgcag ttcggcgggc ggccgtggag
    10921 ccggcacggg ggtggctgcc gtgccggtga acgggcaccg ggcggggagc ggccggtccg
    10981 gctccgtcgc cgcggggcct tcgtccgtcg ccacggtggt cggcgtgcga ggcgccagcc
    11041 ggaccttcag gccctgggcc tggacggtcg tccacaccac ctcgcgggcc cgggcccccg
    11101 gcacggccac cggccgccag cggcgcagga tcgcggcggc cgcgacggtc agctcggccc
    11161 aggcgaaggc ttcgccgatg cacttgtgct tgcccgcccc gaacggcagg aaggagggcc
    11221 gtccgagtcc gccgccgtcc tgccagcgct cgggccggaa gctcagcggt tcgtcgtagc
    11281 ggaccgggtc gcggtgcagt gcggtgaggc tgtacagcag ttcggtgccg gccgggatcc
    11341 ggtacgggcc gaggtccacc ggcacctggg cggtgcgcat caggaaggcg ttgggcgcgt
    11401 gcagtcgcac cacctcctgg gtgacgctgc gggtgtaggt gagccggctg agtgcctcgg
    11461 gagtgggagt ggcaccggca gggaggtgtt cgtccagctc ggcgaggacg cgggcctcca
    11521 cctcggggtg gcgcaggagt tcgtccaaca gccaggtgag ggtggtggag acggtctccg
    11581 taccggcgcc gaacatggtg atggcctcgg agcggacgtc ggcctcggtg agcgcacggc
    11641 cggtggccgg atcggtggcg gcccgcagca gggccggcag ggtgttcccg cgctgcgccg
    11701 aacgggcctt gccggcacgg ccgttgacgg cctgatcgac cacctggttg agcacccgga
    11761 cggcggcgtc gaagcgccgg ttgacgggca gcggcagccg ggcgaacgcc gggtgggggt
    11821 agagggactg gacgatctgg cccttgacca ggtccggcag ggcccggtgg aaggcgaggg
    11881 tggcgtcctc gctgagccgg gcgccgaaca gcgagcgggt gacgatctcc agcgccaggt
    11941 gattcatctc cttggccacg tcgaggactt ggccggaccg ccagcgcccg gcccgctcct
    12001 cggtgacctg gtgcatcacg gccaggtacc cggccatccg gtccgggccg aaggcgggct
    12061 ggatgatccg gcggcggtcg cggtgggcct ggccctcgga catcagcagg ccgtcgccga
    12121 aggccgtctt gagggtgtcc tggacggcgc cgcgcggaca gtcgtgggcg agcgcgacga
    12181 gcagggtgtg gaccagccgg gcgtcggtca ccacgcagac ggtgcgcggc ccgagcctga
    12241 tgcggaccac gccgccgagg cgggccagcg agccgaggaa gccgagcggg tcgcgcagca
    12301 gggcggcggc gtggccgagg ccgggcagcg cgccgggggc gagcgggggg acggcggcgc
    12361 ggacggtggg gacggggggc ggcgtggttc tcggggggac gatccgtttc cgtgtctctg
    12421 ccagcagggc attggtcggc agggccatga cacttcctct caccaggagg accggtgcgg
    12481 gcggtaccgg gggaaggcac cggccggccg gccgggaggc gggggaccgg cgagcgcggt
    12541 tcccgcgtgc acccggggca gagggcgcac gccataggaa acgcgccggt ccgacgggcg
    12601 ttgcgtcgaa cgcgcaggga tcactccaat ggctgatccg cccggagtcc gcccgccgtg
    12661 caccgccgcc ccggccgaca gtacggccca tggcatcggc ctggccagcg gggatgtcca
    12721 tgccctgagg ttcgtgcact acccggaccg cggggtcttt ggaccctcgc ccgcgcggcc
    12781 gtgcgaggcc cagcatggtc ggtggagaag gaagggggcc gggaccatgg actgcgatgg
    12841 cgaggtcatg ctgaccgtcc ggatcgccgc cgccgaacgg gcgctgctgc gggacctggc
    12901 gcgcggtcac ggcggcgacg tctccggggt cgcggtcgac gggctgctgg aggtcatccc
    12961 ggcgctgagc gacgacggtt cggtgctgcc gctgctgcgg gtcctcgccc ggcccgcgcc
    13021 ctgcgcggtg accctctggc tgcccgcccc ggtcgcggac ctgctgccgc tgctgggcga
    13081 gcggctggtg cgcaccggtg ggccggccac cggctcggcc agtgccgcgc tgtccgccgc
    13141 gctgcgactg tggctcgccg gggaccgcgc ggtgctcgcc gccgggctgg cccggctgca
    13201 cggcggttgc ggtgcgaccg ggcgcgcggc ccggtcggcg gtcggcgggg tggcccggat
    13261 cgaggtcgcg gcctgagcgc ttccgctaga tgacgggtcg ccatgtgtcc gacggcgatg
    13321 gcatgtccgg ggcggaaact tccctgttca gggcactggt cacgacctgt cgagaggcct
    13381 ggcgttcgtc acggccgacg gagccgcggg ccccggggct ccggccgggt ggccgccacc
    13441 accccatgcc ggggagcgtg caccccccga gtgcgctccc cggcaccttc gtgcccgtgc
    13501 gcctccgctg aacccttctc cgcgcggccc gtccccgcgc ggctcgtccc cgcgaggctc
    13561 gtccccgcga ggccagtccc tgcgcggccc gtctccacga agccggtctc cgcgcggccc
    13621 gtttcgaacg agtctggaaa tttcgcaaga ggtttctgtt attcccggcc gtccccctcg
    13681 ctctcccttg tgtcggaagg tccgagcccc gcatcaccgg gcgcggaccg tcacacgagg
    13741 agaggaacgc gatgggacac cggagcagcg agctccgtcg gcgcaggcgc cgcaggctca
    13801 cccgcaggag tgccctggtc gccgtggcgg tggcggccgg actggtcgcg ggcacactgg
    13861 gcctgcgcac cgtgctggag ccgggggcgg tgcgcgccac cgtcacggcg gcggacgcgc
    13921 cggtcgacgc ggtcgcggac gacggtgggc cgggggagac cggcaccgcc gagggcgcca
    13981 ccaaggcgcc cgccccgaag cgggacgaga aggtcgcccc gccgaaggcg atacccaagg
    14041 accagcccga acgcggcctg gtctacgccg ggttgaacct gccgaccagt gaccgctgcg
    14101 gcaacatgct ggaggtcacc ggcagcaccc agtgcagcca cggcccggac gcgccgccca
    14161 aggacgtgga catgcgcaag gacgtcccgc cggtcgcggc cccggccgcc caggcgcccg
    14221 cgctcacccc ggcggccggc tcccaaccgc ccgcggccgc cgatctgttg aagggcggcg
    14281 cgcccgtcct cgacgccacc cagaaggcgc tgctcggtgg ctccgccgcc gcctccgccc
    14341 ccgccgccgc ctccggcacc gccgccgaac cgcagggcgc cgcggccccg gccgccggat
    14401 cgggcctggt ctgcgagggc gacggcagca gcggcaaccg cgtccaggtg gtgtacgtgc
    14461 acaccccggg caacgaccgg tacgcccagt acctgtcctc gttcaagaag tgggccgccg
    14521 acgtcgacgt catctacaac gccagcgccg ccgagaccgg cggggtgcgg cacgtccgct
    14581 tcgtcaccga accggactgc accgcctcgg tgttgaacgt gcagatctcg gacgccgaga
    14641 tccaggactt caacgcgagc aaccgcgccc tggccgcgca ggggttcaac cgcaaggacc
    14701 gcaagtacat gatgttcacc gacgccaagg tgtactgcgg gatcggcacc ttcgccggcg
    14761 acgagcgcgc cgggcaggac aacctcagca acttcggccc ctcgtacggt cgcaccgacg
    14821 ccggctgctg gagcggctcc accgccgccc acgaactcgg ccacaacctg ggcgcggtga
    14881 acaacagcgc gccgaactcc agcaaggcgg gccactgcac ggacgagtgg gacatcatgt
    14941 gctactcgga cgccccctac tatccgcaga tgcggaccgt ctgcccggac cgcgcccatg
    15001 acgaccggct cgactgcaac cacgacgact actacaacac gaaccccgcg cccggtagtt
    15061 acctggccac gcactggaac gtcgcgaaca accgcttcct catcgcgggc aacggcaccg
    15121 gcccgaaccc cacgcccacc ccgaccccga cctcgagccc gacggccacc ggcacgccca
    15181 cccgcacgcc ctcgccgtcc ccgacgccca ccggcagccc caccgccacg ccgaccgggt
    15241 ccccgtcgcc gaccgcgacc ccgcccacgg gcagcaccgg tcctgacgtg acggtcagcc
    15301 agatcaccca gaactcggtc atgctgagct ggaaccccgt cccgtccgcc gccggctacg
    15361 acgtccagct gaacggccag accatcggca ccgtccgctc gaccgtggtc ggcgtggtcc
    15421 ggctggcccc cggcaccggc tacacggtgg ccgtcgccgt ccgcgacgcg gccggaacgg
    15481 tcggcaagcc cggtcgccag gcgagcttcc acaccctggc cgacgccggc cgcccgcagc
    15541 ccggcaccca ctacacgatg gtcaacggcc tcaccggcca ggccgccgac ctgtggggca
    15601 gctcgatgaa cgacggcacc gtggcgatcg gctaccagcg caccggctac gccaaccaga
    15661 agtggtcctt cgaggacgcc gggaacggtg cggtgcggat caagtcggtg cggtccggca
    15721 agtgcctgca actcggcggc acgccggtcg ccggacagta cgtggcgcag cagccgtgct
    15781 cggacgccgg cgcgcagaag tggcaactcg cagccggtga cggcgggttc accctcgcgg
    15841 cggacggctc caccctggtg ctcgggctca gcgaccgctg gtactacggt ggttggctgc
    15901 tggagctcca gcagccgaac ggccggccgt accagaactg gtcgctggtg aagacctcgt
    15961 aggtccggaa accccgctcc accgctcgca ccacgggtgc ggccgccatc acccgatggc
    16021 ggccgcaccc ggcgccgccg ctccccgcac cctcaccgtc tccgcccgag gaacgcccgt
    16081 catggtcatc cgcacccgcc cgctgctcgc cgcgctcgcc ctcgccgccg cggccgtcct
    16141 gcccgccgcc gcacccgccg ccgcccacgg cgacaccgtc cacctggagg tggccgggca
    16201 gcggaacggc cggatcagtg ccgtcgccac ctgggagaac gaccacgacc cggtcaccga
    16261 ggacttcgcg ggcacgctgt ccgcgaccgc cgcggacggc cggaccatcg gcccctggcg
    16321 gttggtcgcc gtgccggatc ggccggggac gtacaccact cgggaactgc tgcccgccgg
    16381 gcactggaag gtcgtggtcg actgcgcctt cccctcgctc ggccacggcg agcgcgaact
    16441 cgacgtcgag gcggccgcga tcagcgaccc ggcgccgatg ggcgcagccg ccggggcggc
    16501 cgcccccgcc gcacccgaga ccggcgctcc agcggcggcc atgacggcca ccgccgccgc
    16561 gcccgtccac gggaccaccg acgacgccac cacctgggcc gccaccgcca ccgccaccgc
    16621 caccgcggtc gtcgtcctgg tcgccgtcgg cttccggctg cgcgcccgcg cccgagcccg
    16681 ccgctgacgg accgggaacc ggcgcccgcg ccccggtgat caacaccgca ccgccgaacg
    16741 ggaaccggcc gtgtaccgcg tacgtcccaa cgatcaccgg gcgtcaccgg acacccggcc
    16801 gatcgcaagg gagcaaccgc gcatgaggaa ggtcctgatc accggcggtg ccggcttcat
    16861 cggcagcacg gtggcctccg tcctgctcga ccggggcatc accccggtcg tcctggacga
    16921 cctgtccaag ggccgcgccg agttcgtgcg gaaccgcgtg ttctaccagg gcgacatcgc
    16981 cgacgccgcc ctgctggagc ggatcttcac cgagcacccg gacatcgacg cgaccgtgca
    17041 ctgcgcggcc cggatcatcg tcccggagtc ggtggccaag ccgctgttct actaccggga
    17101 gaacgtcgcc aagaccgtcg aactgctcga cgccctgcag cgccacggct gcacccgggt
    17161 ggtgttcagc agctccgcct cgatctacgc gccgaccccg gacgccaagg tcgacgagag
    17221 ctccgcggtc gaggcgaaca gcccgtacgc gcgcaccaag ctgatgatgg agcaggtgct
    17281 ccaggactgg acccggggcg agggggccga gcagcaacgg gtcatcgccc tgcggtactt
    17341 caacccgatc ggcgccgact cccagctgcg caccggcctg cagaacctca accccagcca
    17401 cgccctcggc aagctgatcg aggcgcacac ctacggcacc ccgttcaccg tcaccggtgt
    17461 cgactggccg acccgggacg ggtccggcat ccgcgactac atccacgtgc aggacctggc
    17521 ggaggcgcac gtcgcggcgc tgctccggtt cgacgaggtg atcgcccccg acgccgccga
    17581 ccgctaccgg gcgatcaacg tcggaacggg cgagggcacc accgtccgtg agctggtcgc
    17641 cgccttcgaa caggccgtcg gcaccgagct ggacgtccgc gaggccgggc cccgcccggg
    17701 tgacgtgatc ggctgctacg cctccgtgga cgccgcccgc gatctgctcg gctgggcacc
    17761 gcaacgcacc ctcgccgagg gtgtcgccga cgcgctggcc tggcgcacca agtgggccgc
    17821 cgaactcggc gtcagctgac cggaccggtc gtcacctcac ggcctcgccg gagcgcgccc
    17881 agttgtcgtg cagccggtcc aggtaggact gcgcctgcgg accgatcttg acgccccggg
    17941 cgaaggcgag catgttgccc gccccggcgt tgtagccgag ggcgagcagc tcgtccttgt
    18001 ccagcggggc gctgacccgg gcggggagct ggccggcgag gtcgtggagg tgccaggcgg
    18061 cggcctggat cgccaggttg cggtcgtccg gcagctcctc ccagcggcgg gaggcgaacg
    18121 ggcggcccgg cttggtgtcg tcgaaggcgg cccggtgcat gttggcgatg ccgaaggcgg
    18181 cgtccggctt gttgcgctgc cacgcccgtt cgaactcggg gtcgtggggt ttgtacgcct
    18241 cgttgtagag gatcgccatc agcagctggg ggttgacccc ggcctcgccg gcgtactggc
    18301 gcacgggcgc cgcgtagtcg gccggttcgt agctgccgga gggcttcgac ggcgatgcgg
    18361 acgacgcgcc cggggaggcg gcggagggcg ccgcggcggt ggtggacggg gacgaggagg
    18421 gcgcggccga ggaggtggcg ggctcgtggc cgcccccgcg gacgatgccc cacccggccg
    18481 ccgccagcac accgatcacg atccagcgcc cccagcggga ccccttctgc tcctcactca
    18541 ccgctgtcgg cccctccccg ttcgcccgtc atccagttcg atcaccgtac ggtcggccgt
    18601 gcctcgtggg aggcccgtcc gaccctattc ggcggtcttc tgctcgccgt cgaggttgcg
    18661 caggaagtcc ttcgccttct cgacaccggt gtcgatctgc ccgctgtact tgccgtccgt
    18721 gcggtcgtcg atcacctcgc cgaccttctc caggccctgc ccgagcacgt cgctgtgctc
    18781 gcgggcgagg tcggtggcct tgtccgcgag gttcttcaga ctctcaaaca tggtgacgct
    18841 ctgctcctct gatgcgttcc tgtaggtgtg ccgacgtggc ggggatcatg gtcatcctgt
    18901 ggcggggatc atggtcatcg taacgagagc cccgaaacgt tcggtcgcgg cggaacggcg
    18961 gcgggtgact ttgctgatat gggtttgtat gctccacatc aacctctaca ggcctgtaga
    19021 cggtgggaac tgccacggga ccggtggcgt cccggcacga gcggtggcgt ggtcgcgccg
    19081 ccgcagccga aacgatcgag ggaagtgcgc atggccggcc agcgggcgag aacgtcgtac
    19141 caggacgcgg gacctcgcac cgaggacccc gccgtgcccg cccagcgctc ccgcgcggcc
    19201 ggcggcgacg ccgacccggc acgggaggcc cgcgcccagc gcggcggggc ctcgcgccgc
    19261 aggcagcagg cccgccggcg tggcggtccg ctcgccgcgc tcacggcggt cgggctgccg
    19321 ctggtcggcg ggatcgcgga cgagctgagc ggccccgggg ccggcatcct gttcgcggtc
    19381 ggcgcggtgc tcggcaccgg cctcgccgcc ctgctgtgca gccgtgccgg ccgttggtgg
    19441 gtggtgaccg ccgccccggt ggtggtgctg ctgaccgcct cgggggtcga atacctgtgc
    19501 aatcccgaca agtaccaggg caagggcctg ggcaccggcg cggtgcgctg gatggtcggg
    19561 gcgttcccgg tgatggcgga ggcggtggcg gtcgtgctgc tggtgatcgt ggtccgggcg
    19621 gtgctcgagc gccgcaggcc cgcccgggcg ggtgccccga gcggaagggg gcgccgtggc
    19681 tgagctcagc aaccgcccgc gcgggcgggt tccgggccgt ggcccggccc cgctgaccgt
    19741 cgccggccgc accctggcct gtgccgtgtc ggtcgccgtg ctcggcgcca gcggcttcac
    19801 ctggtacgag taccgcagcc tggacgacgg cgtgttcaag tccaccgcgc tggccgacgc
    19861 caagaagaac gccccgccgc atctggacaa gtccgtcaac ctgctgctga tcggcctcga
    19921 cagccgcaag gacatggacg gcaacgacct gcccaagcag ttcgtcgagg acgaactgca
    19981 cgccggctcc agtgagatcg gcggctacaa caccaacgcc ctgatcgtgc tgcacatccc
    20041 ggccaacggc ggcaaggtca ccgcgctgtc cgtcccgcgt gacgactacg tgcagaccgt
    20101 cggcgccgac ggcaggatgc acaagatcaa ggaggcctac ggcatcgcca aggaggccgc
    20161 cgaggcgaag ctcgccggca aggccctctc cagggcggag ctggaacggc agagccggga
    20221 ggcgggccgc tcggccacca tccagaccgt gcagagcttc ctggacgtcc cgatcgacca
    20281 cttcgccgag gtcaacctga tcggcttcta cgacatcgcc aaggcggtcg aaccgatcca
    20341 ggtctgcctc aaccacccgg tcgacgatcc gatcatcgcc cggaccgcca cccacgaggg
    20401 cggcggcacc ggcctcaagc tgcccgccgg gatcagctcg ctcgacgccg cccaggcgct
    20461 gtccttcgtc cgccagcgcc accacctgac caacggcgac ctcgaccgca cccaccggca
    20521 gcaggcgttc atctcctcgg tcgagtaccg gctcaagcag cagggcatcc tcaacgactt
    20581 cgggcagatg cagaagctgt tcgaggtggt gaagaaggac gtcgtgatcg acaacgagtg
    20641 gaacgtcctc gacttcgccc agcaggcgcc caacctcacc ggtggcaacg tcgagttcaa
    20701 caccctgccg atcaccgggt tcaagaccat cggcgggcag gaggtcaaca ccgtcaaccc
    20761 ggacctgatc aagaggatcg tccggcagct gttcaaccac gaacaggcgc ccgccgtccc
    20821 ggccacggcg cccggcaacg ccccgagcga gacggccacg tccacgccct cgccgagcgc
    20881 cgcacccaag tccgtggtcg acgtcaacgc ggcggccggt gcgggcgcgg cggccaccga
    20941 gtccaaggcg ctggtcgaac tcggctacca ggcgggaagg atcggggagg ccccggcgcg
    21001 gacccgggcc accgcggtga cgtacggcag cggcgccaag gccgacgccc aggcggtcgc
    21061 cgcccgctac ggcgtcaccg ccgtcccgtc ctcggcggtc gcggcgggcc acgtcctggt
    21121 caccctcgcc gccacccgca ctccgacccc caccccgacc gcgccctcgg cgggtgcctc
    21181 ggctccggcc gacggctcgg ccgacccggc cgccgggttg ccgatgcagg ggccggcggt
    21241 gaaggccggc gggatcccct gcgtcgactg atcggtcatt ccgggtgacg ggcgttcacc
    21301 ggccgggcca gtcgtcgggc cggccgggtc ggtcgggctg ctcgggctgg tggacgcgca
    21361 ggtcccgcag gggctcatgg ccgagcacct cgacgtacat gatccggccg tcgacgacgt
    21421 ccaggaagag ggtgcccttc gcgggtagca gcggcacgca gcgatggccc gggccgtacg
    21481 gctgtccggc ccggtggggc tccgtgtgga agctctggca gaagtcgtcg ccgcagccgc
    21541 agtccgcgac caggcgcaga tcccgggcgt ggacggcgag ttcgggctca ccctcctgct
    21601 ccaggagcgc gaccagctcg tggacgagat cggggaagac ctcgcggacg agggggtggc
    21661 cggtcatggg cgcggtgcct tctcgccgtg gaccgcggag tactcggcgg cgagccagcg
    21721 ggccaggtcg tcgatgagca cggtcaggac ggcgcggtcg gtggtgggtg tgcgggcgac
    21781 ggccgcggcg aggcgcatct gctcggcgcg gtcggggtag tgggcggcga aggcctcggc
    21841 ggagacggtg aggtcgctgg tccagccgtt ccagcggggc atgaccaggg tgaagccggt
    21901 gcggacgatc cggcgcgaga cggtgcggct gagcgctgcg agatcggcgt cctgggcggc
    21961 gacgcccggg gtggcggcgg ccgcgagtcg ttcgcgccag cgggggagga cgagcgcgag
    22021 gtcgccgttg gtctcgcggg cgagcagggg gctcgggcgg tagcggggga gccgcccggc
    22081 gaggtcctcg ccgagcaacg gggtgcagag gcaggcgacg aaccatccca ggtcgtaccg
    22141 ctccaactcg ctgagcagcg tgtccgtgtc gaacaggagc acgccgacgc cgttgacctg
    22201 gggaaaggcc gaatcgaggg cggcctccag gacgtcggcc tcggcgcggt cgtccggggt
    22261 gggccggcgg cgcagggcga gcagcaggtc gaggtcggag acaccgggga ccgcggtgcc
    22321 ccgcgggatg ctgccgtaca ggtaggcgcc gtgcagccgg gcggggccga acgcggcggc
    22381 gatccgctcc cgggcggcgt cgaccaccgg ggcgaactcc gccgtgacgc ggtccagcga
    22441 accctccc
//
