LOCUS       NZ_CP115450            23231 bp    DNA     linear   CON 17-DEC-2024
DEFINITION  Kitasatospora cathayae strain HUAS 3-15 chromosome, complete genome.
ACCESSION   NZ_CP115450
VERSION     NZ_CP115450.1
KEYWORDS    RefSeq.
SOURCE      Kitasatospora cathayae
  ORGANISM  Kitasatospora cathayae
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Kitasatospora.
REFERENCE   1  (bases 1 to 8860963)
  AUTHORS   Zheng,Y., Mo,P., Li,J., Zhou,Z., Huang,K., Luo,Y., Xie,P. and
            Wang,Y.
  TITLE     Kitasatospora cathayae sp. nov., a novel endophytic actinomycete
            isolated from the leaves of Cathaya argyrophylla
  JOURNAL   Int J Syst Evol Microbiol 74 (5) (2024)
   PUBMED   38809239
REFERENCE   2  (bases 1 to 8860963)
  AUTHORS   Mo,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-DEC-2022) College of Life and Environment Science,
            Hunan University of Arts and Science, No. 3150 Dongting Avenue,
            Changde, Hunan 415000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 8.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 155.15x
            Sequencing Technology             :: Oxford Nanopore PromethION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_027627435.1-RS_2024_12_16
            Annotation Date                   :: 12/16/2024 15:42:53
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,288
            CDSs (total)                      :: 8,175
            Genes (coding)                    :: 7,919
            CDSs (with protein)               :: 7,919
            Genes (RNA)                       :: 113
            rRNAs                             :: 11, 11, 11 (5S, 16S, 23S)
            complete rRNAs                    :: 11, 11, 11 (5S, 16S, 23S)
            tRNAs                             :: 77
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 256
            CDSs (without protein)            :: 256
            Pseudo Genes (ambiguous residues) :: 0 of 256
            Pseudo Genes (frameshifted)       :: 79 of 256
            Pseudo Genes (incomplete)         :: 220 of 256
            Pseudo Genes (internal stop)      :: 9 of 256
            Pseudo Genes (multiple problems)  :: 51 of 256
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:37:27
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7169864
            Orig. end                         :: 7193095
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP115450.1.
            Bacteria and source DNA available from Mo Ping.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23231
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="28"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..23231
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23231
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13231](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13231
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            217..810
                     /locus_tag="O1G21_RS32430"
                     /old_locus_tag="O1G21_32430"
     CDS             217..810
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015655450.1"
                     /locus_tag="O1G21_RS32430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_32430"
                     /product="DUF4291 domain-containing protein"
                     /protein_id="WP_270148673.1"
                     /transl_table=11
                     /translation="MAEPKHQIRALHTASTVTVYQAYAPEIGLPAARDGRFPAAWKRDR
                     MTWIKPSFLWMMYRCGWAGKEGQETVLAIEITREGFEWALANSCLSHYEHGLHPDRAAW
                     KHQLKRSPARVQWDPERDLHLRPLPHRSLQLGLAGEAARRYAEEWIVSIADVTTLAHTI
                     HEHVRDRALDAARQLLPAERPYPAGDTLLTHLGG"
     gene            complement(984..1397)
                     /locus_tag="O1G21_RS32435"
                     /old_locus_tag="O1G21_32435"
     CDS             complement(984..1397)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1266: hydrogen
                     peroxide sensitive repressor"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007262054.1"
                     /locus_tag="O1G21_RS32435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_32435"
                     /product="Fur family transcriptional regulator"
                     /protein_id="WP_270148674.1"
                     /transl_table=11
                     /translation="MSDLLERLRERGWRLTSQRRVVAEVLDGEHVHLTADEVHARAAER
                     LPEISRATVYNTLGELVTLGEVLEVSTDGRAKRYDPNAHHPHQHLVCTGCGAIRDVHPL
                     GNPLADLPAEQRFGFAVSGAEVTYRGLCPTCAG"
     CDS             complement(1404..1613)
                     /gene="allorf_7171268_7171477"
                     /locus_tag="allorf_7171268_7171477"
                     /protein_id="allorf_7171268_7171477"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MGILPYKADHGVLLLPTAPISAIAKASAGADPTMDGIQVKKDTKP
                     VSDRETDRSGCRLVNSGLPRDLNR"
     CDS_motif       complement(1524..1613)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MGILPYKADHGVLLLPTAPISAIAKASAGA"
                     /locus_tag="allorf_7171268_7171477_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(1404..1523)
                     /prepeptide="core"
                     /locus_tag="allorf_7171268_7171477_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-0.20"
                     /molecular_weight="4262.7"
                     /monoisotopic_mass="4260.2"
                     /core_sequence="DPTMDGIQVKKDTKPVSDRETDRSGCRLVNSGLPRDLNR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGILPYKADHGVLLLPTAPISAIAKASAGA"
                     /leader_location="[1523:1613](-)"
                     /alternative_weights="4280.7"
                     /alternative_weights="4298.8"
                     /alternative_weights="4316.8"
                     /alternative_weights="4334.8"
                     /alternative_weights="4352.8"
     misc_feature    complement(1500..1513)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 21.45"
                     /tool="antismash"
     misc_feature    complement(1599..1614)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.87"
                     /tool="antismash"
     gene            1612..3828
                     /gene="katG"
                     /locus_tag="O1G21_RS32440"
                     /old_locus_tag="O1G21_32440"
     CDS             1612..3828
                     /EC_number="1.11.1.21"
                     /GO_function="GO:0004096 - catalase activity [Evidence
                     IEA]"
                     /GO_function="GO:0004601 - peroxidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /GO_process="GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="katG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017946997.1"
                     /locus_tag="O1G21_RS32440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_32440"
                     /product="catalase/peroxidase HPI"
                     /protein_id="WP_270148676.1"
                     /transl_table=11
                     /translation="MSENHDATGVEASAGGCPVNHGRALHPTQGGGNRQWWPERLNLKI
                     LAKNPAVANPLGADFDYAEAFNALDLPAVKRDIQEVLTTSRDWWPADYGNYGPFMIRMA
                     WHSAGTYRISDGRGGAGGGQQRFAPLNSWPDNASLDKARRLLWPVKKKYGRSLSWADLI
                     VLAGNVALEGMGFETFGFGGGRVDEWEPDEDVYWGPETTWLGDERYTGDRELESPLAAV
                     QMGLIYVNPEGPNGNPDPIAAARDIRETFYRMAMNDEETVALIAGGHTFGKTHGAGPAD
                     NVGPDPEDAPMEQMGLGWKSSHGTGVGGDAITSGLEGAWTPTPITWDNSFFETLFGYEW
                     ELTKSPAGAHQWKPKDGAGEGTVPDAHDPSKRHVPIMLTTDLSLRFDPVYGPISRRFLE
                     NPAEFADAFARAWFKLTHRDMGPVVRYLGPEVPSEQLLWQDPLPAVTYQQIGAADVADL
                     KRRIAATGLSVSELVSTAWAAASSYRNSDKRGGANGGRIRLQPQAGWEVNEPDRLARVL
                     RALEGVQTEFNAQAGDRQVSLADLVVLAGGVGIEQAAKAAGLAVEVPFAPGRVDAPQEL
                     TDTESFAALEPKADGFRNWVGKGNRLPAEFLLLDKANLLGLSAPELTVLVGGLRVLGAN
                     HQQSAHGVFTETPGVLTNDFFVNLLDLDTSWKSTSEDAHTFEGRDASGKVKWTGTRADL
                     VFGSNSELRAVAEVYAADDAKEKFVEDFVAAWVKVMNADRFDLV"
     gene            complement(3952..4638)
                     /locus_tag="O1G21_RS32445"
                     /old_locus_tag="O1G21_32445"
     CDS             complement(3952..4638)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018837750.1"
                     /locus_tag="O1G21_RS32445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_32445"
                     /product="response regulator transcription factor"
                     /protein_id="WP_270148678.1"
                     /transl_table=11
                     /translation="MNEQRPLRVVVADDQALVRIGFRLILESEGIEVVAEAEDGEQAVA
                     AVRRSRPDVVLMDIRMPGLDGLEATRRILAGAEDAPRIIMLTTFDLDHYVYAAMAAGAS
                     GFLLKDVTPEHLAAAVRLVRTGDALLAPAITRRLVERFARPAAPDAAAPHRELATLTPR
                     ELEVMSLLARGLSNAELAARLQLSEATVKTHVARILGKLGLRDRAQVVVAAYETGLVSV
                     GTPGTP"
     gene            complement(4635..5873)
                     /locus_tag="O1G21_RS32450"
                     /old_locus_tag="O1G21_32450"
     CDS             complement(4635..5873)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014178169.1"
                     /locus_tag="O1G21_RS32450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_32450"
                     /product="sensor histidine kinase"
                     /protein_id="WP_270148679.1"
                     /transl_table=11
                     /translation="MINHPAVQRLLSGGTGSPAPPPRPTRRGQAFDLALALFLCYTCGR
                     YATVAHRTHGPDTTAWPGPLLLVPLVPLPLALRRRYPLTVLWAVLPAALLVRSQHRDIA
                     FWEGVAVIVAAYSAAAYGRRPKALLPSLAAATGALVVLFDDALLPHFPNAVVALFVLVP
                     VFAVAYELRMWRRRVEEGRERLSALEREQLAALRHAVEHERARIARELHDVVTHNVSMM
                     TIQAGAARKILDTAPEKAREAMAAVEAGGRAAMTELRHVMGLLTIDSETGDDPAASADL
                     SPQPGLGRLDALVEGVRRAGLPVELTVRGEHRAVPPGVELAAYRVVQEALTNTVKHAGG
                     TDATVTVDYASDHLRVEVTDTGGRPTGAAATGNGRGLLGLRERLAVYGGTLHTGPRPRG
                     GYRVTASIPLESR"
     gene            6082..6828
                     /locus_tag="O1G21_RS32455"
                     /old_locus_tag="O1G21_32455"
     CDS             6082..6828
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018382782.1"
                     /locus_tag="O1G21_RS32455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_32455"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_270148680.1"
                     /transl_table=11
                     /translation="MDSDPVIGLSGVSRHYEGARAALDGVTLNVRAGESVAVLGPSGSG
                     KSTLLNLVAGLDRPSAGTVTVDGVRVDRLNESGSARYRRRTIGMVFQFFNLLDDLTVAD
                     NVVLAGELAGVPRAEARRRAAELLEALGVDRHVRAHPGRLSGGERQRVAVARALMNRPA
                     VLLADEPTGALDSASGEDVKELFRELHEDGQTILIVTHDLTLAEDCATRTVRMRDGRVE
                     SDTADTADTPDTAGSAGSAGSAEVAA"
     gene            6825..9215
                     /locus_tag="O1G21_RS32460"
                     /old_locus_tag="O1G21_32460"
     CDS             6825..9215
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018510998.1"
                     /locus_tag="O1G21_RS32460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_32460"
                     /product="FtsX-like permease family protein"
                     /protein_id="WP_270148681.1"
                     /transl_table=11
                     /translation="MSALGRVVRAGVRRRRTQSVAVGLAALVATTCSVLGGSLLVASEA
                     PFDQAFDGQHGAHLTARFDGTRVSADQLAATGHAAGVTASAGPFRTVTVDPEPGPGSTV
                     MAGVTMSSMTVTGRASADIGVDNISLVQGSWATKPGDVVLASGYPNPGVPIGGTLRLPG
                     LPGAPSLTVVGIGRSVSRTADAWVTPETIPALTVPGSAPGYEMLYRFAQAGTADAMAAD
                     RAAVAAATPGGALTGAQSWLTAKQGSDRNTALFLPFVVAFGLLGMAMSVLVAGNVVAGA
                     VGTATRRIGVLKAIGCTPAQVVRAYVAQALVPATVGTLLGVVAGNALTVPVLATAGNLY
                     GTHASGVAPWVDVAVAGGTLAAVALVAWVAAARAGRLRTVDALAVGRTAGGTRRDAVAR
                     RVAALAARLPLPRPLSLGLAQPFARPARAAGMFAAVLFGTAAAVFAVGMGGSLTWVQEA
                     KNHDRSDVLVHPDRRDVPTEAWSIAGRTPAAGADPAAVTAALTAQPGTAAYYGVGTEDV
                     TVPGVAGNTTVTAFVGDSSWGGYRMVSGRWHQGPGEAVAPSTFLTEASVKLGDQVTFTS
                     HGRAVTVRIVGEVFDPHMQTNELFTDAASYPAGTAPKPDSWFVKLRSGTDRAAYTTALG
                     STLAPLHLVIDTDVAHGSSDSVAVMNSLTATLTTLLVAVAGLGVFNTVVLEIRERTRDM
                     GVTKALGMTPAQTVGVVLASVLLVGAAGAAIGLPAGLLLHGVTVPAMGHRAGLTFPASA
                     LDVFGTPMLALLGFGGVLIALLGALAPALRAARARTVDALRAE"
     misc_feature    complement(9374..9389)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     gene            9693..9872
                     /locus_tag="O1G21_RS32465"
                     /old_locus_tag="O1G21_32465"
     CDS             9693..9872
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O1G21_RS32465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O1G21_32465"
                     /product="hypothetical protein"
                     /protein_id="WP_270148682.1"
                     /transl_table=11
                     /translation="MQPTAEQVRALKDEDFRLTLGQGHQVHPAGEPADELYVTAAVMLN
                     TCESWGSCGRVCSY"
     gene            10001..13231
                     /locus_tag="O1G21_RS32470"
                     /old_locus_tag="O1G21_32470"
     CDS             10001..13231
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="O1G21_RS32470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_32470"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_270148683.1"
                     /sec_met_domain="DUF4135 (E-value: 5.2e-94, bitscore:
                     314.3, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1e-54, bitscore:
                     184.5, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADASELLRAAARAVPLNARGRVPEGSPRSEPVRAADRAADRDES
                     GERHARAARKLERWRSQAPFDRADWFARRLAADGLDPDALRALLAEHPDALADRLGAHP
                     WAEQLAAAFHGAATLDVPEEHEFAGLVAPLLAAARDRLCTGLAALDLPPVGTPSLGTPE
                     ELAALALPALTATAHGIATRTVITELHVARLTGELTGDTPELRYREFLDRLTEPERALR
                     LLAEYPVLAVRLTTLAEQWADTTLTLFHRLAADLPALARTFADGHPLGRLIELTTGLGD
                     PHRGGATVSSLTFEHGVRLVYKPRPLGAETHFQQLLHWLNPQLRLPLRDLAHLAGDGYG
                     WVAHVTAEPARDEAELSAFYHRAGTLAALMYVLDAVDCHAQNLLAVRDQPVLIDLEAIL
                     HPDLHEPAKDLSESERLARHRARHSVLRSGLLPERMWDEGNGGADISALGWDPANLPPR
                     PVPVLVNRGTDELRLEYRRLPVEAPGSRPVPTGQPLRPADHLAELEAGFTEAYRLLAAD
                     KPQLRSLLRAFAADETRLLRRDTFEYRTLLNTACHPDLLRDALDQDRHLDRLWALAGWE
                     EHALAFVEHERADLWRGDVPVFTIRPDSVDARSSTGALIPGVTDRPALDLALAKADGLG
                     EEDLARQLQLLRLSVTTADGAREPGRAVADAPREVFITPGGDLASRALAKAVEAGEQLL
                     REAYRGNADLAWTGPNWTPPGRWAPAELGPDLYSGTAGIALFLHQLSLATGDTAHREAA
                     QAAEVTLRQQIRRRADRLGGGLSGTGGVLYVLAHLVAHHPDPALDELGTLVLQRVTATA
                     TEDTQHDLLAGNAGTIGGLLAWEAVRPGPAVTAALAACAERLVQSATPHPEGGAGWLPA
                     SLAETASRPLAGFAHGGSGIAWALARAGHRLGDPRLPQLALAAVEYERTLFDAGAANWR
                     DVREDGGPDAPSFPALWCHGAAGIALARTTLAEILPEQRELLLAERDTALATVLREGFG
                     HNSSLCHGDLGNLEALHLAGAPWQPATHQQAHATLHTLDTTGWTCGLPHGVHSPSLMVG
                     LAGIGHGLLRLAAPGTTPSVLLLEPPAQ"
     gene            13625..15568
                     /locus_tag="O1G21_RS32475"
                     /old_locus_tag="O1G21_32475"
     CDS             13625..15568
                     /EC_number="7.-.-.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014060120.1"
                     /locus_tag="O1G21_RS32475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_32475"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_270148684.1"
                     /transl_table=11
                     /translation="MTEQIVKPEKPQVEEREGEHDEELRLRFPGDRRAAAGASMSASAM
                     LRRLPHLVRRALALAWSADRTSTVLLLVCQALAGVFGALALYATTGTLTALLVPGPVTG
                     HLRTAAPSLLLLTASAGLRAVLGIAVVGLSGRVSPRITREAELALIAAGCAAELKAYDE
                     PAYNEQWEAADRGASTTPDLLSNAQDVIASTVSLAAAAGVLATLHPWLVPLLLLGSVPT
                     AVAAVRTARIHYLAAVTTNEDRGALRVYRWFLVDKTRADQVRSDQVTPFLMAKYRRAEA
                     KIVAATDRATREAAKVSLLAALGTGAGSALIWGALLYLVASGRIDLAAAGTATFALRTA
                     SSGLQGLVGNGARLYRMGLYLDDYFSFLDEAGGHRINRGHLVPAAPQLVEVSELCHSYP
                     GEQQEPALRGVSMTLRAGEMVAVIGQNGSGKSTLLKLLSGLYLPQSGRITWDGVPVEEL
                     DADGMWARVARVPQEFARWPLGAAENVHLGHLTERLMADVEEAAARTGFDEIVARLRSG
                     WRTLLAQGWWGGAELSGGGWQRAAVARALYRTVRSPGLLILDEPTSDLDPRAEHRILHA
                     LRGLAPGRITLLVTHNIANAAVADRVIVMDKGRIVQAGTWAELAARPDGLFRELLDLQR
                     DRAVPAQRAAGD"
     gene            15838..16290
                     /locus_tag="O1G21_RS32480"
                     /old_locus_tag="O1G21_32480"
     CDS             15838..16290
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010064334.1"
                     /locus_tag="O1G21_RS32480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_32480"
                     /product="DUF5990 family protein"
                     /protein_id="WP_270148685.1"
                     /transl_table=11
                     /translation="MELRIEATDLPGRECGAGPGFPGYRDIHVAVQRRGRPAELLDPQP
                     GDAPRARWSLECAVKRLPDGGADVTGRYVQGGPGGRFIYLNWVTRDGDDWRLFRRAKLL
                     LAAVDQGTLESAADTGLLVARLGLTDAKGHPLCAAVRPPLVTWSPA"
     gene            complement(16279..16739)
                     /locus_tag="O1G21_RS32485"
                     /old_locus_tag="O1G21_32485"
                     /pseudo=""
     CDS             complement(16279..16739)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018853469.1"
                     /locus_tag="O1G21_RS32485"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_32485"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGAIGCDRGTVTRATGAPVVVLGIESVASSPHPRRTGRRDAAAAL
                     QEAIADVLTRKAVRACTDHGIGALVVVGGVAANSRVRALAEQRCAAAGIALRVPPLRLC
                     TDNGAMVAAIGDLLVRAGPSRRPPGCRWIRRRRRSSRRSVRCRCRH"
     misc_feature    complement(16812..16830)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.2"
                     /tool="antismash"
     misc_feature    complement(16813..16829)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 24.68"
                     /tool="antismash"
     gene            16887..17489
                     /locus_tag="O1G21_RS32490"
                     /old_locus_tag="O1G21_32490"
     CDS             16887..17489
                     /EC_number="1.15.1.1"
                     /GO_function="GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018385873.1"
                     /locus_tag="O1G21_RS32490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_32490"
                     /product="superoxide dismutase"
                     /protein_id="WP_270148686.1"
                     /transl_table=11
                     /translation="MGTYTLPDLPYDYSALERAMSAEILELHHSKHHAAYVKGANDTLE
                     QLAEARDKEQFGGLVGLQKTFAFHLSGHVLHSLFWQNLSPEGGDRPEGELADAITEHFG
                     GFEAFKKQLTTATTGVQGSGWGILSWEPLGQRLIVEQVYDHHGNVGQGTTPLLAFDAWE
                     HAYYLQYRNVRPDYVTRLWDVVNWQDVSARFAAVKSA"
     CDS             complement(17567..17665)
                     /gene="allorf_7187431_7187529"
                     /locus_tag="allorf_7187431_7187529"
                     /protein_id="allorf_7187431_7187529"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MPTAGEQRVAASLRFGMTAVPRVNGRDACQRP"
     CDS_motif       complement(17630..17665)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MPTAGEQRVAAS"
                     /locus_tag="allorf_7187431_7187529_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(17567..17629)
                     /prepeptide="core"
                     /locus_tag="allorf_7187431_7187529_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.30"
                     /molecular_weight="2226.6"
                     /monoisotopic_mass="2225.2"
                     /core_sequence="LRFGMTAVPRVNGRDACQRP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MPTAGEQRVAAS"
                     /leader_location="[17629:17665](-)"
     CDS             complement(17586..17687)
                     /gene="allorf_7187450_7187551"
                     /locus_tag="allorf_7187450_7187551"
                     /protein_id="allorf_7187450_7187551"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MVRAYRSCAHGGRTAGGGESSFRYDCRAACQRP"
     CDS_motif       complement(17637..17687)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MVRAYRSCAHGGRTAGG"
                     /locus_tag="allorf_7187450_7187551_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(17586..17636)
                     /prepeptide="core"
                     /locus_tag="allorf_7187450_7187551_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.20"
                     /molecular_weight="1810.0"
                     /monoisotopic_mass="1808.8"
                     /core_sequence="GESSFRYDCRAACQRP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MVRAYRSCAHGGRTAGG"
                     /leader_location="[17636:17687](-)"
     gene            17758..18807
                     /locus_tag="O1G21_RS32495"
                     /old_locus_tag="O1G21_32495"
     CDS             17758..18807
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123: polyprenol-monophosphomannose synthase ppm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012745.5"
                     /locus_tag="O1G21_RS32495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_32495"
                     /product="glycosyltransferase"
                     /protein_id="WP_270148687.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 9e-34, bitscore:
                     115.6, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPRLSVVVPIYNVERYLGECLDSIAAQTFEDFECVMVDDGSTDD
                     GPVIAKAYADRDRRFRLVQQENKGLGAARNTGWRHLTPGTEYLAFVDSDDTLPPHAYQL
                     MISTLDETGSDFATGNAMRLRTTGLTPSHAHRRPFAETRLRTHVSETPALVTDRTAWNK
                     VYRRTFFDAAGIQYPEGILYEDAPVSVPHHFLAERVDVLAEPIYHWRVREDGALSITQK
                     KTDPRGLIDRVRSMELVREWLLARPEPQFASYLGAYDRNCLVEEIPMFFWSIPDGDRNY
                     WEVYQRHVSRLLHAIGPDRVADLNAQLRLKYRLTLADAMNRFIAVQRLHRAVRRTRQAA
                     QAAAAVHRR"
     gene            complement(18841..19701)
                     /locus_tag="O1G21_RS32500"
                     /old_locus_tag="O1G21_32500"
     CDS             complement(18841..19701)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018540052.1"
                     /locus_tag="O1G21_RS32500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_32500"
                     /product="biotin-dependent carboxyltransferase family
                     protein"
                     /protein_id="WP_270148688.1"
                     /transl_table=11
                     /translation="MTVTVMSAGLLTTVQDLGRPGHAHLGVPRSGALDQPAHRLANRLV
                     GNPATAATLETTVLGCAVRVDRAVTVAVAGAPCAVRVDGRPAAWAAPVRLPAGALLEVG
                     AATRGVRSYVAFAGGIAAAPVLGSRSTDLLSGLGPAPLAPGDALPLGEPVGPAAGADVV
                     PAPAPPDPLLLPVLFGPRDDWFTARSLAVLTGSGYRVSPTSNRIGLRLDGPPLERAREG
                     ELPSEGMVLGAVQVPPDGRPVVFLADHPTTGGYPVIGVVPAAALPAVAQAAPGTPVRFT
                     PVGRR"
     gene            complement(19741..20358)
                     /locus_tag="O1G21_RS32505"
                     /old_locus_tag="O1G21_32505"
     CDS             complement(19741..20358)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010468751.1"
                     /locus_tag="O1G21_RS32505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_32505"
                     /product="allophanate hydrolase subunit 1"
                     /protein_id="WP_270151373.1"
                     /transl_table=11
                     /translation="MRVLRVGLDALLVELDDADETMAFHAELQRRRAASQLPPVTEVVP
                     AERTVLLDGVADPEALAAELADWHVPPLRATSDETVTIPVRYDGADVAEVAALWGVAEE
                     EVARIHSATEFRVAFSGFAPGFGYLTGLPERYRVPRRAVPRPAVPTGAIALAGRYTGAY
                     PRSSPGGWQLIGHTDAVLWDPSRERAALFSPGTRVRFVIEEA"
     gene            complement(20448..21230)
                     /locus_tag="O1G21_RS32510"
                     /old_locus_tag="O1G21_32510"
     CDS             complement(20448..21230)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003985620.1"
                     /locus_tag="O1G21_RS32510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_32510"
                     /product="LamB/YcsF family protein"
                     /protein_id="WP_270148689.1"
                     /transl_table=11
                     /translation="MTPAERPPVTVVDLNADLGEGFGRWTLTDDDALLSVVTSANVACG
                     FHAGDPTTMRRVCELAAERGVRIGAQVSYRDLAGFGRRAMDVPPDQLADEVAYQIGALQ
                     VFARAAGARVAYVKPHGALYNRTVHDEEQAEAVVGGVRLAAPGLPVLGLPGSRLHEAAG
                     RAGLPVVAEAFADRAYTPHGTLVPRREPDAVVHDPDAVVDRSVAIARDGEVTAHTGDRI
                     RLRARSLCVHGDTPGAADLARRVRTALWTAGVRVEAFA"
     gene            complement(21227..22006)
                     /locus_tag="O1G21_RS32515"
                     /old_locus_tag="O1G21_32515"
     CDS             complement(21227..22006)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015032202.1"
                     /locus_tag="O1G21_RS32515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_32515"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_270148691.1"
                     /transl_table=11
                     /translation="MTGVFDALAADRGRLERASAAQRVAEVLRDHITEGLLAPGTRLSE
                     EALGEALTVSRNTLREAFRLLADERLVVHELNRGVFVRILEPADVADIYTLRLALETAG
                     VRSLRCAAPERLAAVRAALNRAEAAEAIGDWVTVGTADLHFHQAVAGIAGSERIDECMA
                     RLVAELRLAFAAVPSARGLHAPFLRRNQTLTGLLESGEIDDAEVELTSYLNDARAVIVR
                     AMAGSAMAGSAMADSVMTDGSMAGDATAGSAMTDGAR"
     misc_feature    22033..22049
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.07"
                     /tool="antismash"
     gene            22179..22919
                     /locus_tag="O1G21_RS32520"
                     /old_locus_tag="O1G21_32520"
     CDS             22179..22919
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018531320.1"
                     /locus_tag="O1G21_RS32520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_32520"
                     /product="DUF969 domain-containing protein"
                     /protein_id="WP_270148692.1"
                     /transl_table=11
                     /translation="MIVLVGILVVVAGFATRRNPLLVVGAAGVLTGLLGGMSPLKVLDA
                     FGTGFASSRSVTVFAVTLPVIGLLERHGLQEQARTLMNKLARASAGRVLAVYLVLRQLT
                     AAFGLTGLGGPAPAVRPMVVPMAEAAAERRHGTLTDKARERLRSFAASADNVGLFFGED
                     CFLAVGSILLITGFVNATYHAALEPVQLALWAIPTAVCATLIHGARLLRLDHTLARDLP
                     ATGPGQAATADQPTTADRIEETSK"
     misc_feature    22935..22950
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.5"
                     /tool="antismash"
ORIGIN
        1 acggtgctga tggtgcgcgg ctgaggggac tctgggtgca cgtcgaagta cttcgccatt
       61 ggccgaccct acgggatccc ggccaccgac gggcgcagcc gcgacatcca gccctccgca
      121 gggcggccgg ggcgccgggg cgcgcagcgt ccccgccccg tcgggcccgc gaaaatccgc
      181 tggcgcgatg cgtgccgagc ctcgaccctg gtcaccgtgg cagaacccaa gcatcagatc
      241 cgcgccctcc atacggcctc cacggtgacc gtctaccagg cgtacgcccc ggagatcggc
      301 ctgcccgccg cacgggacgg tcgctttccg gcggcgtgga agcgggaccg gatgacgtgg
      361 atcaaaccgt cgttcctctg gatgatgtac cgctgcggat gggccgggaa ggagggacag
      421 gagaccgtcc tcgcgatcga gatcacccgc gagggcttcg aatgggccct tgcgaacagc
      481 tgcctgtccc actacgaaca cggcctgcac cccgaccggg cggcctggaa gcaccagttg
      541 aagcggtccc cggcccgggt gcagtgggat cccgaacgcg atctgcacct acggccgctt
      601 ccccaccgct cgcttcagct cggcctcgcc ggcgaggccg ccaggcgcta cgcggaggag
      661 tggatcgtct cgatcgccga cgtcacgacg ctcgcgcaca cgatccacga gcatgtgcgg
      721 gaccgggctc tggacgccgc ccggcaactc cttcccgccg aacgccccta cccggcaggc
      781 gacacgctgc tgacccacct gggcggctga gccgctcccg cgtcgctcct cggcgaactt
      841 ctcgccggcg ccgtccggca atccgacgcc cccgacgacc gccccgtcga gatccgctcc
      901 gccctcgccg gatccgtctc cgacccgcgg ccagcctgcg cagcccgcgg tcagcccgcg
      961 gtcagcccgc ggtcagcccg cggtcagccc gcgcaggtcg ggcagagccc ccggtacgtg
     1021 acctcggccc ccgagacggc gaagccgaag cgctgttcgg ccgggaggtc ggcgagcggg
     1081 ttgccgaggg ggtggacgtc gcggatcgcg ccgcagccgg tgcagaccag gtgctggtgc
     1141 gggtggtggg cgttggggtc gtagcgcttg gcgcgcccgt cggtggacac ctcgaggacc
     1201 tcgccgaggg tgaccagctc gccgagggtg ttgtagaccg tcgcgcggga gatctccggg
     1261 aggcgctcgg ccgcgcgggc gtgcacctcg tcggcggtca ggtgcacgtg ctcgccgtcc
     1321 aggacctcgg ccacgacacg ccgctgggag gtgaggcgcc agccgcgctc gcgcagccgc
     1381 tccagcaggt cactcataac ggttcaccta ttcaggtcac ggggaagacc ggagtttacc
     1441 aatcgacatc cgctgcggtc cgtttcccga tcggatacgg gtttggtgtc tttcttgact
     1501 tggattccgt ccatcgtagg atcggctccg gcgctagcct tggcaatagc agagataggt
     1561 gccgtaggta gcagcaagac accgtgatcc gccttgtagg gaaggattcc catgtctgag
     1621 aaccacgatg cgaccggcgt agaggcgagc gcgggcggct gcccggtcaa ccacgggcgc
     1681 gcgctccacc ccacccaggg cggcgggaac cgccagtggt ggccggaacg gctgaacctg
     1741 aagatcctcg ccaagaaccc cgccgtggcc aacccgctcg gcgcggactt cgactacgcc
     1801 gaggcgttca acgccctcga cctcccggcc gtcaagcggg acatccagga ggtgctcacc
     1861 acctcgcggg actggtggcc ggccgattac ggcaactacg gtccgttcat gatccggatg
     1921 gcctggcaca gcgccggcac ctaccggatc agcgacggcc gcggcggcgc aggcggcggc
     1981 cagcagcgct tcgccccgct gaacagctgg ccggacaacg ccagcctgga caaggcccgc
     2041 cgcctgctct ggccggtgaa gaagaagtac ggccgcagcc tgtcctgggc cgacctgatc
     2101 gtcctggccg gcaacgtcgc gctggagggg atgggcttcg agaccttcgg cttcggcgga
     2161 ggccgggtcg acgagtggga gccggacgag gacgtctact ggggcccgga gaccacctgg
     2221 ctgggcgacg agcgctacac cggcgaccgc gagctggaga gcccgctggc cgccgtccag
     2281 atgggtctga tctacgtcaa ccccgagggc cccaacggca accccgaccc gatcgccgcc
     2341 gcccgcgaca tccgcgagac cttctaccgg atggcgatga acgacgagga gaccgtcgcg
     2401 ctgatcgccg gcggccacac cttcggcaag acccacggcg ctggcccggc ggacaacgtc
     2461 ggcccggacc cggaggacgc gccgatggag cagatgggcc tcggctggaa gagcagccac
     2521 ggcaccggtg tcggcggcga cgcgatcacc agcggcctgg aaggcgcctg gacgccgacc
     2581 ccgatcacct gggacaacag cttcttcgag acgctgttcg gctacgagtg ggagctcacc
     2641 aagagcccgg ccggcgccca ccagtggaag ccgaaggacg gcgccggcga gggcaccgtg
     2701 ccggacgccc acgacccgag caagcggcac gtgccgatca tgctcaccac cgacctgtcg
     2761 ctgcgcttcg acccggtgta cggaccgatc tcccggcgct tcctggagaa cccggcggag
     2821 ttcgccgacg ccttcgcccg cgcctggttc aagctgaccc accgcgacat gggcccggtg
     2881 gtgcgctacc tcggccccga ggtcccgagc gagcagctgc tctggcagga cccgctgccg
     2941 gccgtcacgt accagcagat cggtgcggcg gacgtcgccg acctcaagcg gcggatcgcc
     3001 gccaccggcc tgtcggtctc cgagctggtc tccaccgcct gggccgccgc ctcctcgtac
     3061 cgcaacagcg acaagcgcgg cggcgccaac ggcggccgga tccggctgca gccgcaggcc
     3121 ggctgggagg tcaacgagcc ggaccggctg gcccgcgtgc tgcgcgcgct cgagggcgtg
     3181 cagacggagt tcaacgccca ggccggcgac aggcaggtct cgctggccga cctggtggtg
     3241 ctggccggtg gcgtcggcat cgagcaggcg gccaaggcgg ccggcctggc cgtcgaggtg
     3301 ccgttcgcgc ccggccgggt ggacgccccg caggagctga ccgacaccga gtccttcgcc
     3361 gcactggagc ccaaggcgga cggcttccgc aactgggtgg gcaagggcaa ccggctgccg
     3421 gccgagttcc tgctgctcga caaggcgaac ctgctgggcc tcagcgcgcc cgaactgacc
     3481 gtgctggtcg gcggcctgcg cgtgctgggt gccaaccacc agcagtccgc gcacggggtg
     3541 ttcaccgaga ccccgggcgt gctgacgaac gacttcttcg tcaacctgct ggacctggac
     3601 accagttgga agtccacctc ggaggacgcc cacaccttcg agggccggga cgcctccggc
     3661 aaggtcaagt ggaccggtac ccgggccgac ctggtcttcg gctccaactc cgaactgcgc
     3721 gccgtcgccg aggtgtacgc ggccgacgac gccaaggaga agttcgtcga ggacttcgtc
     3781 gcggcctggg tcaaggtcat gaacgcggac cgcttcgacc tggtgtgaca gctgtgaggt
     3841 aggcgggagc ccggggcgtc aacccccggg ctcctgttcg tcgttacggc ctaccgggtc
     3901 ttacggtgta ccgggtctta cggtgtaccg ggcgttacgg cgttcccgtc ctcacggcgt
     3961 cccgggcgtt cccacgctga ccagcccggt ctcgtacgcc gcgaccacca cctgggcccg
     4021 gtcccgcagc cccaacttgc ccagaatccg ggccacatgg gtcttcaccg ttgcctcgga
     4081 cagctgcagc cgggcggcca gctcggcgtt gctgaggccg cgggcgagca gcgacatcac
     4141 ctccagctcg cgcggggtga gggtggccag ttcccggtgc ggggcggccg cgtccggggc
     4201 ggccgggcgg gcgaagcgct cgaccaggcg tcgggtgatc gcgggggcga gcagtgcgtc
     4261 gccggtgcgg accagccgga cggcggcggc caggtgctcc ggggtgacgt ccttgagcag
     4321 gaagccgctg gccccggcgg ccatcgcggc gtagacgtag tgatccaggt cgaaggtggt
     4381 cagcatgatg atccggggcg cgtcctccgc gccggcgagg atccgccggg tggcctccag
     4441 tccgtccagg ccgggcatcc ggatgtccat cagaacgacg tccggtctgc tccgccggac
     4501 cgcggcgacg gcctgctcgc cgtcctcggc ctcggcgacc acctcgatcc cctcggactc
     4561 caggatcagc cggaacccga tccggaccag tgcctggtca tcggcgacca ccacgcgcaa
     4621 gggccgctgc tcgttcaacg actctccagc ggtatcgagg ccgtgacgcg gtagccgccg
     4681 cgcggccggg ggccggtgtg cagggtgccg ccgtagacgg cgaggcgttc gcgcagcccg
     4741 agcaggccgc gaccgttgcc ggtggcggcg gcgccggtgg ggcggccgcc ggtgtcggtg
     4801 acctccaccc gtaggtggtc ggaggcgtag tcgacggtca ccgtggcgtc ggtgccgccc
     4861 gcgtgcttga cggtgttggt gagcgcctcc tggacgaccc ggtaggcggc gagttcgacc
     4921 ccgggcggga cggcccggtg ctcgccgcgc acggtcagct ccaccggcag tccggcccgg
     4981 cggacgccct cgaccagggc gtcgagcctt ccgaggccgg gctgcgggct gaggtcggcg
     5041 ctcgccgccg gatcgtcccc ggtctccgag tcgatggtca acaggcccat cacgtgccgc
     5101 agttcggtca tcgcggcgcg tccgccggcc tccaccgccg ccatcgcctc ccgggccttt
     5161 tccggggcgg tgtccaggat cttgcgggcg gcgccggcct ggatcgtcat catgctcacg
     5221 ttgtgggtca cgacgtcgtg caactcccgg gcgatgcggg cccgttcgtg ctccaccgcg
     5281 tgccgcagcg cggccagctg ctcgcgctcc agggccgaca gtcgctcccg gccctcctcc
     5341 acccggcggc gccacatccg cagttcgtag gcgaccgcga acaccggtac caggacgaac
     5401 agggcgacca ccgcgttcgg gaagtgcggc agcagggcgt cgtcgaagag caccacgagc
     5461 gcgccggtgg cggccgccag gctcggcagc agggccttcg gccggcgccc gtacgcggcc
     5521 gcgctgtagg cggcgacgat caccgccacg ccctcccaga acgcgatgtc ccggtgctgc
     5581 gaccgcacca gcagcgcggc cggcagcacc gcccacagca ccgtcagcgg gtagcgccga
     5641 cgcagcgcca gcggcagcgg gacgagcggc accagcagca acggcccggg ccaggcggtg
     5701 gtgtccgggc cgtgggtgcg gtgcgcgacg gtggcgtagc ggccgcaggt gtagcagagg
     5761 aacagggcca gggccaggtc gaaggcctgg ccgcgccggg tcggccgggg cggcggagcc
     5821 gggctgcccg ttccgccgct cagcagccgt tgtactgcgg ggtggttgat cactgggaca
     5881 ttctggcggt cggccgctcc cgggcacagc cccgcgactg gcggcagccc gtacaccggg
     5941 tgactacctc ggaaggatga cgccgagccg ggtccgccgg acgcggtacg gaagatgccg
     6001 tcgtcggcgg acgcgggtgc gcgccgcccg tccgtagctt cgtcctcgtc accaggcggg
     6061 aagcgatgag gagcggggaa gatggacagc gatccggtga tcgggctgag cggtgtgagc
     6121 cgccactacg agggtgcgcg ggcggcgttg gacggggtga cgctgaacgt gcgggcgggg
     6181 gagtcggtgg ccgtgctcgg tccgtcgggc agcgggaagt ccaccctgct gaacctggtc
     6241 gccgggctgg accggccgag cgccgggacg gtcaccgtcg acggggtccg ggtggaccgg
     6301 ctgaacgagt cgggttcggc ccggtaccgg cggcggacga tcggcatggt gttccagttc
     6361 ttcaacctgc tggacgacct cacggtcgcc gacaacgtgg tgctggccgg cgaactggcc
     6421 ggcgtcccgc gcgccgaggc ccggcggcgg gccgccgagc tgctggaggc gctcggcgtc
     6481 gaccggcacg tccgcgccca cccgggccgg ctctccggcg gtgagcgcca acgcgtggcg
     6541 gtggcgcggg cgttgatgaa ccggccggcc gtgctgctgg ccgacgagcc gaccggcgcg
     6601 ctggactcgg cctccgggga ggacgtcaag gaactgttcc gggagctaca cgaggacggc
     6661 cagaccatcc tgatcgtcac ccacgacctg accctcgccg aggactgcgc cacccgcacc
     6721 gtccggatgc gggacggccg ggtcgagtcg gacacggcgg acacggcgga cacgccggac
     6781 acggcgggct cggcaggctc ggctggctcg gcggaggtgg cggcgtgagt gccctcggtc
     6841 gtgtcgtccg cgccggggtg cgcaggcgcc ggacccagtc ggtcgcggtc gggctggccg
     6901 ccctggtcgc gaccacctgc tccgtcctcg gcggttcgct gctggtcgcc tccgaggctc
     6961 ccttcgacca ggccttcgac ggccagcacg gcgcccacct caccgcgcgc ttcgacggca
     7021 cccgggtgag cgccgatcag ctcgccgcca ccgggcacgc cgccggggtg acggccagcg
     7081 ccggcccctt ccgcaccgtg accgtcgacc ccgagccggg ccccggctcg accgtcatgg
     7141 cgggcgtgac gatgtcgtcg atgacggtca ccggccgtgc ctcggccgat atcggtgtcg
     7201 acaacatctc gctcgttcag gggagttggg cgaccaagcc gggcgacgtg gtgctcgcct
     7261 ccgggtaccc gaacccgggc gtgccgatcg gcgggaccct ccgcctgccc ggcctgccgg
     7321 gcgcgccctc gctgacggtc gtcggcatcg gccggtccgt cagccggacc gccgacgcct
     7381 gggtgacgcc cgagaccatc cccgccctca ccgtgcccgg cagcgcaccc gggtacgaga
     7441 tgctctaccg cttcgcacag gccggcaccg ccgacgcgat ggccgccgac cgggccgccg
     7501 tcgccgccgc cacgcccggc ggggcgctca ccggcgccca gtcctggctc accgccaagc
     7561 agggctcgga ccgcaacacc gccctgttcc tgcccttcgt ggtcgccttc ggcctgctcg
     7621 gcatggcgat gtcggtgctg gtggcgggca acgtggtggc cggcgcggtc ggcaccgcga
     7681 cccggcggat cggcgtgctc aaggcgatcg gctgcacccc cgcccaggtg gtgcgcgcct
     7741 acgtcgccca ggcgctggtc ccggccacgg tcggcaccct gctcggcgtg gtggccggca
     7801 atgcgctgac cgtcccggtg ctcgccaccg ccgggaacct ctacggcacc cacgcctccg
     7861 gcgtcgcgcc ctgggtggac gtcgcggtgg ccggcggcac gctcgccgcc gtcgccctgg
     7921 tcgcctgggt cgccgccgcc cgcgccggac ggctgcgcac cgtggacgca ctggccgtcg
     7981 gccgtacggc gggcggcacc cggcgtgacg ccgtcgcccg ccgggtcgcc gcgctggccg
     8041 cccggctgcc gctgccccgg ccgctgagcc tcggcctcgc ccagcccttc gcccggccgg
     8101 cccgggccgc cgggatgttc gcggctgtgc tgttcggcac ggcggcggcg gtcttcgcgg
     8161 tcggcatggg cggctcgctg acctgggtgc aggaggcgaa gaaccacgac aggtcggacg
     8221 tcctcgtgca cccggaccgg cgcgacgttc caaccgaggc ctggtcgatc gcggggcgca
     8281 cgccggccgc cggagccgac ccggcagccg tcaccgccgc cctcaccgcc cagccgggca
     8341 ccgccgccta ctacggcgtc ggcaccgagg acgtcaccgt ccccggagtc gccgggaaca
     8401 ccaccgtgac cgccttcgtc ggtgactcct cctggggcgg gtaccggatg gtctccggcc
     8461 gctggcacca gggcccgggc gaggccgtcg cccccagcac cttcctgacc gaggcctcgg
     8521 tgaagctcgg cgaccaggtg accttcacca gtcacgggcg ggcggtcacc gtccggatcg
     8581 tcggcgaggt cttcgacccg cacatgcaga ccaacgagct gttcaccgat gccgccagct
     8641 acccggccgg cacggccccc aagcccgaca gctggttcgt caagctcagg agcggcaccg
     8701 accgcgccgc ctacaccacc gccctcggca gcacgctcgc cccgctgcac ctggtcatcg
     8761 acaccgacgt ggcgcacggc tcctccgact cggtcgcggt catgaactcg ctcaccgcca
     8821 cgttgaccac gctgctggtc gccgtcgccg ggctcggggt gttcaacacc gtcgtcctgg
     8881 agatccgcga acgcacccgg gacatgggcg tcaccaaggc actcggcatg accccggcgc
     8941 agaccgtggg cgtggtgctg gcctcggtgc tgctggtcgg agcggccggc gccgcgatcg
     9001 gcctgccggc cggactgctg ctgcacggcg tgacggtgcc cgcgatgggc caccgcgccg
     9061 ggctcacctt cccggcctcc gccctggacg tcttcggcac gccgatgctc gccctgctcg
     9121 gcttcggcgg tgtgctgatc gccctgctcg gcgccctcgc gcctgcccta cgggcggcgc
     9181 gggcgcggac ggtggacgcg ctgcgggcgg agtgacggag cgtctcagac gtacagacat
     9241 ctcagacgaa tgtcttgcgc attcgtctga gatgtctgtc ttgtgcctca ggcgtgtcca
     9301 tgtgtcttgt gcattcgtct tgtgcattcg tcttggacat gcgtcttgga catttcgtct
     9361 cgtactcccg gccgggactc catcgtgacc ctcggtgcgg ggcgctgcca aaggagcgag
     9421 tggttcaaac cgcgatgcgg ttcccctcgg atccaccacc tgtgttccgg ccaggtgtgg
     9481 ggccgtccga acgatcggac ggtcggccgg ggttgcggtc cgggcggggt gcggcctggg
     9541 ggaacggggt tggggcggtc cggcgggcgt tgattcgatc ctggccggaa cgaggaccga
     9601 ccgtgcgtac gcgtctggtg tgccgccggg ggcgctgtca agatccggtt tcggcacgcc
     9661 cgtgccagac ccgaacgctt ggaggaggca gcatgcagcc cacggctgag caggttcgcg
     9721 cactcaagga cgaggacttc cggctcaccc tcggccaggg acaccaggtc cacccggccg
     9781 gtgagccggc cgacgagctc tacgtcaccg ccgcggtgat gctcaacacc tgtgagagct
     9841 ggggcagctg cggacgcgtc tgcagctact gaggccgggt ccggtactgg gcccgggccg
     9901 gtcgtacagt cggaccgggg ccagtgccgg acggggcgtc cagcgcccgt gtgagagcgc
     9961 agccagtaca accgtgcatt cagaaaggca gcaccgcccc gtggccgacg cgtccgaact
    10021 cctgcgggcc gccgcccgag ccgtcccgct gaacgcccgc ggccgggtgc cggagggatc
    10081 gccccgctcg gagcccgtcc gcgccgccga tcgcgccgcc gatcgcgacg aatccggtga
    10141 gcgccacgcg cgcgccgccc ggaagctgga gcgctggcgg tcccaggcgc cgttcgaccg
    10201 ggccgactgg ttcgcgcgcc ggctcgcggc cgacggtctc gaccccgacg ccctgcgcgc
    10261 cctcctcgcc gagcacccgg acgcgctcgc cgaccgcctc ggggcgcacc cgtgggccga
    10321 gcagctcgct gcggccttcc acggcgcggc caccctggac gtccccgagg agcacgagtt
    10381 cgccgggctg gtcgccccgc tgctcgccgc cgcccgcgac cgcctgtgca ccggactggc
    10441 cgccctggac ctgccgcccg tcggcacccc cagcctcggc acccccgagg aactggccgc
    10501 gctcgccctg cccgcgctca ccgccaccgc ccacgggatc gccacccgga ccgtcatcac
    10561 cgaactccac gtcgcccgcc tcaccggcga gttgaccggc gacacccccg agctgcggta
    10621 ccgcgagttc ctcgaccggc tcaccgaacc cgagcgggca ctgcggctcc tcgccgagta
    10681 ccccgtcctg gccgtccgcc tcaccaccct cgccgagcag tgggccgaca ccaccctcac
    10741 cctgttccac cgcctcgccg ccgacctgcc cgccctcgcc cgcaccttcg ccgacggcca
    10801 cccgctcggc cggctcatcg aactcaccac cggcctcggc gacccgcacc gcggtggcgc
    10861 cacggtcagt tcgctgacct tcgagcacgg cgtccgactc gtctacaagc cccggccgct
    10921 cggcgccgag acccacttcc agcagctcct gcactggctc aacccgcaac tgcggctgcc
    10981 cctgcgcgac ctcgcccacc tggccggcga cggctacggc tgggtcgccc acgtcaccgc
    11041 cgaacctgcc cgggacgaag ccgagttgag tgccttctac caccgagccg gcactctcgc
    11101 cgcactgatg tacgtcctgg acgcggtcga ctgccacgcc cagaacctgc tcgccgtccg
    11161 ggaccagccc gtgctcatcg acctcgaggc gatcctccac cccgacctgc acgagcccgc
    11221 caaggacctc tccgaatccg aacggctcgc ccgccaccgg gcccggcact cggtgctgcg
    11281 ctccggtctg ctccccgaac gcatgtggga cgagggcaac ggcggcgccg acatctccgc
    11341 cctgggctgg gacccggcca acctcccacc ccgccccgtg cccgtcctgg tcaaccgggg
    11401 aacggacgaa ctccggctgg aataccggcg gttgcccgtc gaagcccccg gcagccgccc
    11461 cgttccgacc ggacagccgc tgcggccggc cgaccacctg gcggagctgg aggcgggctt
    11521 caccgaggcc tatcggctgc tcgccgccga caagccgcaa ctccggtcgc tgctccgcgc
    11581 gttcgcggcc gacgagacca ggttgctgcg ccgcgacacc ttcgagtacc gcaccctgct
    11641 caacaccgcc tgccaccccg acctgctccg cgacgccctc gaccaggacc gccacctcga
    11701 ccggctctgg gcactggccg gctgggagga gcacgcgctc gccttcgtgg aacacgagcg
    11761 cgccgacctg tggcgcggcg acgtgcccgt cttcaccatc cgccccgaca gcgtcgacgc
    11821 ccgctcctcc accggcgccc tcatcccggg cgtcaccgac cggccggccc tcgacctcgc
    11881 cctcgccaag gcggacggcc tcggcgagga ggacctcgcc cgccaactcc agctgctgcg
    11941 gctctcggtg acgacggccg acggagcgcg cgagccggga cgggccgtcg ccgacgcccc
    12001 gcgagaggtg ttcatcacgc cgggcgggga cctggcgtcc cgcgccctcg ccaaggccgt
    12061 cgaagccggc gagcagctgc tccgcgaggc ctaccgggga aacgccgacc tggcctggac
    12121 cggccccaac tggaccccgc ccggccgctg ggcccccgcc gagctcggtc cggacctgta
    12181 cagcggcacc gcgggcatcg ccctcttcct ccaccaactc tccctggcca ccggcgacac
    12241 ggcgcaccgc gaagccgccc aggccgcaga ggtgacgcta cgtcagcaga tccggcgacg
    12301 cgccgaccgg ctcggcggtg gcctgtccgg taccggcggt gtgctctacg tgctcgccca
    12361 cctcgtcgcc catcacccgg atcccgcact cgacgagctc ggcaccctcg tcctccagcg
    12421 cgtcaccgcc accgccaccg aggacaccca gcacgacctc ctcgccggaa acgccggcac
    12481 catcggaggc ctcctcgcct gggaggccgt ccgtcccggc cccgccgtca ccgccgcgct
    12541 cgccgcctgc gccgaacgac tcgtccagag cgccaccccg caccccgagg gcggcgccgg
    12601 ctggctgccc gcctccctcg ccgagaccgc gagccgcccc ctggccggct tcgcccacgg
    12661 cggctccggc atcgcctggg ccctggcccg ggccggacac cgcctcggcg acccgcgcct
    12721 gccccaactc gccctcgccg cggtcgagta cgagcgcacc ctgttcgacg ccggcgccgc
    12781 caactggcgc gacgtccgcg aggacggcgg ccccgacgcc ccgtccttcc ccgccctctg
    12841 gtgccacggc gccgcaggca tcgccctggc ccgcaccacc ctcgccgaaa tccttcccga
    12901 gcagcgcgag ttgctcctcg ccgaacgcga caccgcgctc gccacggtcc tccgggaggg
    12961 cttcggccac aactcgtcac tctgccacgg cgatctcggc aacctggaag ccctccacct
    13021 cgccggcgcc ccctggcagc ccgccaccca ccagcaggcc cacgccaccc tccacaccct
    13081 ggacaccacc ggctggacct gcggcctgcc acacggcgtc cacagcccct ccctgatggt
    13141 cggcctggcc ggcatcggcc acggcctcct ccgcctcgcc gcccccggca ccaccccgtc
    13201 cgttctcctc ctcgaaccgc ccgcgcagtg accccttgcg ggcctcggct cgagggtggt
    13261 tgggcgcggg gcctgcgccg ggcgtgcggt ctgccgcacg gcgtccacag ccgaccggct
    13321 tgggcggtag gtctttccga ccgtcggatc gcatgcccgg cagtatgtcc gcaatcgaac
    13381 atcgcggacc tccgcagtga tcgacatcca ccaacccgcc gtcgccgaca cggaatcgcc
    13441 cggatcgggt gagagcgacc gggacacgcc ggacgccccc gccgaccgct gccaggatcg
    13501 gggtccgcac cggcagcccg cccttcgcgg agtgcccacc ggcaccgctg ccgacccgtc
    13561 acgcccaccc ggcgctgagg gctgcccgcg tgcggaagcc gtggccgtac cagggaggaa
    13621 tgctgtgaca gagcagatcg tgaagccaga gaagccccag gtcgaggagc gcgagggcga
    13681 acacgacgag gagctgcgcc tgcgcttccc cggggaccgc cgcgccgcgg ccggcgcgtc
    13741 gatgtcggcg agcgcgatgc tgcgccgcct gccgcacctg gtgcgccggg cgctggccct
    13801 ggcctggtcg gcggaccgca cgtccaccgt gctgctgctg gtctgccagg cgttggccgg
    13861 cgtgttcggc gcgctggcgc tgtacgccac caccggcacc ctgaccgcgc tgctggtccc
    13921 gggtccggtg acgggccacc tgcggaccgc cgcgccgtcc ctgctcctgc tgaccgcctc
    13981 ggccgggctg cgcgccgtcc tgggcatcgc ggtggtgggc ctgtccggcc gggtgtcgcc
    14041 gcggatcacc agggaggcgg agctggcgct gatcgccgcc gggtgcgccg ccgagctgaa
    14101 ggcgtacgac gagcccgcgt acaacgagca gtgggaggcc gccgaccggg gtgcctccac
    14161 cacgcccgac ctgctctcca acgcccagga cgtgatcgcc tccaccgtct cgctggccgc
    14221 cgcggcgggc gtgctggcga cgctccaccc gtggctggtg ccgctgctgc tgctcggttc
    14281 ggtgccgacc gccgtcgccg ccgtccgcac cgcgcgcatc cactacctgg ccgcggtgac
    14341 caccaacgag gaccgtggcg cgctgcgcgt ctaccgctgg ttcctggtcg acaagacccg
    14401 ggccgaccag gtccgttcgg accaggtcac gccgttcctg atggccaagt accgccgcgc
    14461 cgaggccaag atcgtcgccg ccaccgaccg ggccacccgc gaggcggcca aggtttcgct
    14521 gctggccgcg ctcggcaccg gggcgggcag cgcgctgatc tggggagcgc tgctgtacct
    14581 ggtcgccagt ggccggatcg acctcgccgc agccggcacg gccaccttcg cgctgcgcac
    14641 cgcctcctcc ggcctgcagg gcctggtcgg caacggcgcc cggctgtacc ggatgggtct
    14701 ctacctggac gactacttca gcttcctgga cgaggccggc ggccaccgca tcaaccgcgg
    14761 ccacctggtg cccgccgctc cgcagctggt ggaggtgtcc gaactgtgcc actcctaccc
    14821 gggtgagcag caggagcccg ccctgcgcgg cgtcagcatg accctgcggg cgggggagat
    14881 ggtcgccgtg atcgggcaga acggcagcgg caagtcgacc ctgctgaagc tgctgtcggg
    14941 cctctacctg ccgcagtcgg gccggatcac ctgggacggc gtgccggtgg aggaactgga
    15001 cgcggacggc atgtgggcac gggtcgcccg ggtgccgcag gagttcgccc gctggccgct
    15061 cggcgccgcc gagaacgttc acctgggcca cctcaccgag cggctgatgg ccgacgtgga
    15121 ggaggccgcg gcccgcaccg gcttcgacga gatcgtcgcc cggctgcgct ccggctggcg
    15181 caccctgctc gcccaaggct ggtggggcgg cgccgagttg tcgggcggcg gatggcagcg
    15241 cgcggccgtc gcccgggccc tctaccgcac ggtgcgcagc ccggggctgc tgatcctgga
    15301 cgagcccacc tctgacctcg acccgcgcgc cgagcaccgc atcctgcacg ccctgcgcgg
    15361 cctcgccccg ggccggatca ccctgctggt cacccacaac atcgccaatg cggcggtcgc
    15421 cgaccgggtg atcgtgatgg acaaggggcg gatcgtccag gccggcacct gggccgaact
    15481 cgccgcccgc ccggacgggt tgttccgcga actcctcgat ctgcagcggg accgcgccgt
    15541 cccggcccag cgcgcggcag gggactgacc caccgcctga cccgccgcct gacccgccgg
    15601 tgccgccggg cggacggcca ggagccgtcc gcccggcggt gcgcggaaag ggaggggaaa
    15661 cgcccggccg gatgaaccac gatgacggca tgcgaatcaa cgaggagccg ggtgagggtg
    15721 cggacaccga ggagcagctg ccgcagcgcc tggtcggcga agtctgggcc aacgtctgcg
    15781 ctgacccccc ccgaacgaac cggcgggtcc agcctgggat gggggacgat ggacggcatg
    15841 gagctgagga tcgaggccac cgacctgccc ggacgcgagt gcggcgccgg gcccgggttc
    15901 cccgggtacc gggacatcca cgtcgccgtc caacgccggg gtcgccccgc cgagttgctc
    15961 gacccgcagc ccggcgacgc gccgcgggcg cggtggtcgc tggagtgcgc ggtgaagcgg
    16021 ctgccggacg gcggggcgga cgtcaccggt cggtacgtcc agggcgggcc gggcggccgg
    16081 ttcatctacc tgaactgggt gacgcgggac ggcgacgact ggcggctgtt ccgccgggcg
    16141 aagctgctgc tggccgcggt ggaccagggc accctcgaaa gcgccgccga caccggtctg
    16201 ctggtcgccc ggcttggcct caccgacgcc aagggccacc cgctgtgcgc cgccgtccgc
    16261 ccgcccctgg tcacctggtc acctgcttag tgacgacagc ggcaacggac tgagcgccgc
    16321 gaactccggc ggcgccgacg gatccaccga cagcccggcg ggcgccggct gggccccgca
    16381 cggaccagca ggtcgccgat cgccgcgacc atcgcgccgt tgtccgtgca cagccgcagc
    16441 ggcggcaccc gcagggcgat gccggccgcc gcgcagcgct gctcggcgag cgcccgcacc
    16501 cgggagttgg ccgcgactcc gccgaccacc accagggcgc cgatcccgtg gtcggtgcag
    16561 gcccgcaccg ccttgcgggt gagcacgtcc gcgatcgcct cctgaagggc ggccgccgcg
    16621 tcccgacggc cggtccgccg ggggtgtgga ctgctggcga ctgactcgat gcccagcacg
    16681 accaccggcg cccccgtcgc ccttgtcaca gttcccctgt cacagccaat cgcgcccatc
    16741 agtcattaca cgttcggatg accattgtgc ccgacgggat gtgaggaaca agtaggagcc
    16801 tgtgctgcgc tcctgcaagt catacgcaat agtgttgtcc cggcacgatc gtcagcactc
    16861 aacccgtcga aaggagccgt gtcctgatgg gcacctacac gcttcccgac ctgccgtacg
    16921 actactccgc gctcgagcgg gccatgtccg ccgagatcct ggagctgcac cactccaagc
    16981 accacgccgc gtacgtgaag ggcgcgaacg acaccctgga gcagctcgcc gaggcgcgcg
    17041 acaaggagca gttcggcggc ctggtcggcc tgcagaagac cttcgccttc cacctgtccg
    17101 gtcacgtgct gcactcgctg ttctggcaga acctgtcccc ggagggcggc gatcgccccg
    17161 agggcgagct ggccgacgcc atcaccgagc acttcggcgg cttcgaggcc ttcaagaagc
    17221 agctcacgac cgccaccacc ggcgtccagg gctcgggttg gggcatcctc tcctgggagc
    17281 cgctcgggca gcgcctgatc gtcgagcagg tctacgacca ccacggcaac gtgggccagg
    17341 gcaccacccc gctgctggcc ttcgacgcct gggagcacgc ctactacctg cagtaccgca
    17401 acgtccgccc cgactacgtc acccgtctgt gggacgtcgt caactggcag gacgtctcgg
    17461 cccgcttcgc cgccgtcaag agcgcctgag cgtcgagtga gcaggagggc cccggaccgg
    17521 tcgggcggtc cgggccttcc ccctgtggcc ccatggtcgt tgcccgtcac ggccgttgac
    17581 acgcgtcacg gccgttgaca cgcggcacgg cagtcatacc gaaacgaaga ctcgccgcca
    17641 cccgctgttc gcccgccgtg ggcacacgat cggtacgctc ggaccaccgc cggtcaccgg
    17701 cggtcggcgg ccgaccggcc gatccggccc gcccgctcct gagcgaaagg tcgtccgatg
    17761 gctccgcgcc tgtccgtcgt ggtcccgatc tacaacgtcg agcgctacct cggcgaatgc
    17821 ctggactcga tcgcggccca gaccttcgag gacttcgagt gcgtcatggt cgacgacggc
    17881 tcgaccgacg acggccccgt catcgccaag gcgtacgccg acagggaccg gcgcttccgg
    17941 ctcgtccagc aggagaacaa gggcctcggt gccgcccgca acaccggctg gcgccacctc
    18001 acccccggca ccgagtacct ggccttcgtc gacagcgacg acaccctgcc gccgcacgcc
    18061 taccagctga tgatcagcac gctcgacgag accggctccg acttcgcaac cggcaacgcg
    18121 atgcgcctgc gcaccaccgg cctcaccccc tcgcacgccc accgccgccc cttcgccgag
    18181 acccggctgc gcacccacgt cagcgaaact cccgccctgg tcaccgaccg caccgcctgg
    18241 aacaaggtct accggcgcac cttcttcgac gccgccggca tccagtaccc cgaaggcatc
    18301 ctgtacgagg acgcgcccgt cagcgtcccc caccacttcc tcgccgagcg cgtcgacgtc
    18361 ctcgccgagc cgatctacca ctggcgggtc cgcgaggacg gtgccctctc catcacccag
    18421 aagaagaccg acccgcgcgg cctgatcgac cgggtccgct cgatggaact cgtccgcgag
    18481 tggctgctcg cccgtcccga gccgcagttc gcctcgtacc tgggtgcgta cgaccgcaac
    18541 tgcctggtcg aggagatccc gatgttcttc tggtccatcc cggacggcga ccgcaactac
    18601 tgggaggtct accagcggca cgtcagccgc ctcctccacg cgatcggccc cgaccgggtg
    18661 gccgatctca acgcccaact acggctcaag taccggctca ccctggccga cgcgatgaac
    18721 cgcttcatcg ccgtccaacg cctccaccgc gccgtccgcc gcacccgcca ggccgcccag
    18781 gccgcggctg cggtgcatcg gcgctgacct cgctgagccc ggacgccctg ctaccgccgc
    18841 ctacctccgg cccaccggtg tgaaccggac aggcgtgccc ggggcggcct gggcgacggc
    18901 gggtagggcg gcggccggga cgacgccgat gacggggtag ccgccggtgg tgggatggtc
    18961 ggcgaggaag accaccgggc ggccgtccgg cgggacctgc accgcgccca ggaccatgcc
    19021 ctcgctgggg agttcgccct cgcgggcgcg ctccaggggc gggccgtcca gccgcaggcc
    19081 gatccggttg ctggtggggg agacgcggta gccggagccg gtgaggacgg cgagggaacg
    19141 ggcggtgaac cagtcgtcgc gcgggccgaa cagtacgggc aggagcagcg gatcgggcgg
    19201 cgcgggcgcc ggcaccacgt ccgccccggc ggccggcccg accggctcac cgagcggcag
    19261 cgcgtccccg ggggccagtg gagcggggcc cagccccgag agcagatcgg tcgaacggct
    19321 gccgaggacc ggagcggcgg cgatcccacc cgcgaaggcg acgtagctgc gcacaccccg
    19381 cgtcgcggcg cccacctcca gcagtgctcc ggcgggcagc cgcaccgggg cggcccaggc
    19441 ggcgggccgc ccgtcgaccc gcaccgcgca cggtgcgccg gccacggcga ccgtcaccgc
    19501 gcgatccacc cgcaccgcgc agccgagcac ggtggtctcc agggtggccg ccgtcgcggg
    19561 gttgccgacc aggcggttgg cgagccggtg ggcgggctgg tcgagcgcgc cggagcgcgg
    19621 cacgcccagg tgcgcgtgcc cgggccggcc gaggtcctgg acggtcgtca gcaggcctgc
    19681 gctcatcacg gttacggtca tgcgtcctcg atcacgcttc cctcgaatgc gaatcctcgg
    19741 tcaggcttcc tcgatcacga accggacccg ggtccccggg ctgaacagtg cggcgcgttc
    19801 gcgggacggg tcccacagca cggcgtcggt gtgtccgatc agctgccagc cgcccggtga
    19861 ggagcgcggg taggcgccgg tgtaacggcc ggcgagggcg atcgccccgg tcgggacggc
    19921 ggggcgcggg acggcccgcc ggggcacccg gtagcgctcg ggcaggccgg tcaggtagcc
    19981 gaagccgggg gcgaagccgc tgaaggcgac gcggaactcg gtcgcggagt ggatgcgcgc
    20041 gacctcctcc tcggcgacgc cccacagcgc ggcgacctcc gcgacgtcgg cgccgtcgta
    20101 gcgcaccggg atggtcacgg tctcgtcgct ggtcgcccgc agcggcggta cgtgccagtc
    20161 ggccaactcg gcggccaggg cctcggggtc ggccaccccg tcgagcagga cggtccgttc
    20221 ggcgggcacg acctcggtga cgggcgggag ttgggacgcc gcgcgtcggc gctggagttc
    20281 ggcgtggaag gccatcgtct cgtcggcgtc gtcgagctcg accaggagcg cgtccaggcc
    20341 gacccgcagg acccggatgt tcaccccgtt cgccgcgttc accgcgttca ccgtgttcac
    20401 cgtgttcgtc gcgttcgccc ctgtccgtct gccgctccgc tcggcgctca tgcgaacgcc
    20461 tcgacccgga ctccggccgt ccacagggca gttcggaccc ggcgggcgag gtccgccgcc
    20521 ccgggggtgt cgccgtgcac gcacagcgaa cgggcccgca gccggatccg gtcgccggtg
    20581 tgcgccgtga cctcgccgtc ccgggcgatg gcgaccgagc ggtcgacgac ggcgtcgggg
    20641 tcgtggacga ccgcgtcggg ttcacgacgg ggcacgagcg tgccgtgcgg ggtgtaggcg
    20701 cggtcggcga acgcctcggc gaccaccggc agtccggccc gtccggcggc ctcgtgcagc
    20761 cgggaaccgg gcagtccgag gacgggaaga cccggtgcgg ccagccggac gccgccgacc
    20821 accgcctccg cctgttcctc gtcgtgcacc gtccggttgt acagcgcgcc gtgcggtttg
    20881 acgtacgcca cccgcgctcc ggccgcccgc gcgaacacct gcaacgcccc gatctggtaa
    20941 gcgacttcgt cggcgagctg gtcgggcgga acgtccatcg cccggcgccc gaacccggcg
    21001 aggtcccggt aggagacctg cgcgccgatc cgcacgcccc gctcggcggc cagctcgcac
    21061 acccgccgca tggtggtcgg gtccccggcg tggaagccgc aggcgacgtt ggcgctggtg
    21121 accaccgaca gcagggcgtc gtcgtcggtg agcgtccagc ggccgaagcc ctcgccgagg
    21181 tcggcgttga ggtcgacgac cgtgacggga gggcgctcgg ccggtgtcat ctcgcgccgt
    21241 ccgtcatcgc gctccccgcc gttgcgtccc ccgccatcga gccgtcggtc atgacgctgt
    21301 ccgccatcgc gctccccgcc atcgcgctcc ccgccatcgc ccggacgatc accgcgcgag
    21361 cgtcgttcag gtagctggtc agctccacct cggcgtcgtc gatctcgccc gactccagca
    21421 gcccggtgag cgtctggttg cggcgcagga acggcgcgtg cagcccgcgc gccgacggga
    21481 cggcggcgaa ggccaggcgc agctcggcca ccaggcgggc catgcactcg tcgatccgct
    21541 cgctgccggc gatccccgcg acggcctggt ggaagtgcag gtcggcggtg ccgacggtga
    21601 cccagtcgcc gatcgcctcg gcggcctccg cgcggttcag cgcggcccgc accgcggcca
    21661 ggcgctcggg cgccgcgcag cgcagggagc gcacaccggc cgtctccagg gcgaggcgca
    21721 gggtgtagat gtcggcgacg tcggccggtt cgaggatccg gacgaacacg ccgcgattca
    21781 gctcgtgcac gaccagccgc tcgtcggcca gcagccggaa cgcctcgcgg agcgtgttgc
    21841 gcgagacggt gagcgcctcg ccgagcgctt cctccgacag tcgggtgccg ggggcgagca
    21901 ggccctcggt gatgtggtcg cgcagcacct cggccacccg ttgggcggcg ctggcacgtt
    21961 cgagccggcc ccggtcggcc gcgagcgcgt cgaaaacccc ggtcacgttc cacctcctga
    22021 actcttgtcg gattgttcca caatccccta gcctcgcggc aacccccgca gggtcgcggc
    22081 ccacccagcc gtgacctcct ccgtccgtgg tgccgcagac cgtggtgccg cggacggcca
    22141 tcctcggggc gcaggccctc tgaaaggcgg tcaggaacat gatcgtgctc gtcggcatcc
    22201 tcgtcgtggt ggccgggttc gccacccggc gaaatccgct cctcgtcgtc ggcgccgccg
    22261 gcgtcctcac cggactgctg ggcgggatga gcccgctgaa ggtcctggac gccttcggca
    22321 ccggcttcgc ctccagccgc tcggtgaccg tcttcgccgt caccctgccg gtgatcggcc
    22381 tgctggaacg ccacggcctg caggaacagg cccgcaccct gatgaacaag ctcgccaggg
    22441 ccagcgccgg acgcgtgctc gcggtctacc tggtgctccg ccaactcacc gccgccttcg
    22501 gcctcaccgg cctcggcgga ccggccccgg ccgtacgtcc gatggtcgta ccgatggccg
    22561 aggccgccgc cgaacgccgc cacggcaccc tgaccgacaa ggcccgcgaa cgcctgcgct
    22621 ccttcgccgc gagcgccgac aacgtcggcc tgttcttcgg cgaggactgc ttcctcgccg
    22681 tcggctcgat cctcctgatc accggtttcg tcaacgcgac ctaccacgcc gccctggagc
    22741 cggtgcagct cgccctgtgg gccatcccca ccgcggtctg cgccaccctc atccacggcg
    22801 cgcgcctgct gcgcctggac cacaccctcg cccgcgacct gcccgccacc gggccgggcc
    22861 aggcggccac cgcagaccag ccgaccaccg ccgaccgcat cgaggagacg agcaagtgat
    22921 caaggtcgag tggctgtact ggctggtcgg agccgtcttc ctcgcgatgg ccgcccagat
    22981 ggcggtggac cgcggcaacc ccaggcgtta cggcagcgcc gccttctggg gcctgctcgg
    23041 cgcgagcttc gtctacggca cctgggtcgc cgacaagagc gcccccgccg caccgctcgg
    23101 cgtcgccgtc ctggcgatga tctgcctggc cggcttcggc ttcaccggtc gcggcacccc
    23161 cacggccgcc gcccccgaac agcggtccgt ctccgccgcc cgcctgggca atcgactgtt
    23221 catccccgcg c
//
