LOCUS       NZ_CP115450            23018 bp    DNA     linear   CON 17-DEC-2024
DEFINITION  Kitasatospora cathayae strain HUAS 3-15 chromosome, complete genome.
ACCESSION   NZ_CP115450
VERSION     NZ_CP115450.1
KEYWORDS    RefSeq.
SOURCE      Kitasatospora cathayae
  ORGANISM  Kitasatospora cathayae
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Kitasatospora.
REFERENCE   1  (bases 1 to 8860963)
  AUTHORS   Zheng,Y., Mo,P., Li,J., Zhou,Z., Huang,K., Luo,Y., Xie,P. and
            Wang,Y.
  TITLE     Kitasatospora cathayae sp. nov., a novel endophytic actinomycete
            isolated from the leaves of Cathaya argyrophylla
  JOURNAL   Int J Syst Evol Microbiol 74 (5) (2024)
   PUBMED   38809239
REFERENCE   2  (bases 1 to 8860963)
  AUTHORS   Mo,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-DEC-2022) College of Life and Environment Science,
            Hunan University of Arts and Science, No. 3150 Dongting Avenue,
            Changde, Hunan 415000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 8.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 155.15x
            Sequencing Technology             :: Oxford Nanopore PromethION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_027627435.1-RS_2024_12_16
            Annotation Date                   :: 12/16/2024 15:42:53
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,288
            CDSs (total)                      :: 8,175
            Genes (coding)                    :: 7,919
            CDSs (with protein)               :: 7,919
            Genes (RNA)                       :: 113
            rRNAs                             :: 11, 11, 11 (5S, 16S, 23S)
            complete rRNAs                    :: 11, 11, 11 (5S, 16S, 23S)
            tRNAs                             :: 77
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 256
            CDSs (without protein)            :: 256
            Pseudo Genes (ambiguous residues) :: 0 of 256
            Pseudo Genes (frameshifted)       :: 79 of 256
            Pseudo Genes (incomplete)         :: 220 of 256
            Pseudo Genes (internal stop)      :: 9 of 256
            Pseudo Genes (multiple problems)  :: 51 of 256
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:37:27
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5976127
            Orig. end                         :: 5999145
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP115450.1.
            Bacteria and source DNA available from Mo Ping.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23018
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iv"
                     /region_number="21"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     cand_cluster    1..23018
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23018
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13018](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13018)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     gene            459..1520
                     /locus_tag="O1G21_RS26750"
                     /old_locus_tag="O1G21_26750"
     CDS             459..1520
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135551.1"
                     /locus_tag="O1G21_RS26750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_26750"
                     /product="prenyltransferase"
                     /protein_id="WP_270147203.1"
                     /transl_table=11
                     /translation="MTPAVPEVLLLDGVLDAEQAADTVRSILAEQRPDGAIPWFAGHHL
                     DPWDHTEAAMALDTAGEHAAAEAAYRWLAAQQNPDGSWYAAYTDGVVTDRAKESNFCAY
                     IAVGVWHHHLSAGDDAFLEWIWPVVRRALDFIVGLRLPDGPIAWRVDEDGAATGEALLT
                     GSSSILHALRCGLAIADYLEEPQPDWELAAGRLRHAIAHHPERFLDKGRYSMDWYYPVL
                     GTGLRGDAALARIERDWDRFVVPGLGVRCVSDRPWVTGGESAELALALWAIGQSDRAVD
                     ILRWIQKHLRHQDGSYWTGYVFEDDAIWPEERTTWTAGALLLAVAALGGDPATVAVFGG
                     EQLPAGLVVQDCC"
     gene            complement(1587..2492)
                     /locus_tag="O1G21_RS26755"
                     /old_locus_tag="O1G21_26755"
     CDS             complement(1587..2492)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019546071.1"
                     /locus_tag="O1G21_RS26755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_26755"
                     /product="hypothetical protein"
                     /protein_id="WP_270147204.1"
                     /transl_table=11
                     /translation="MNLRALTRGDAAVAGAAVLLFIASFLPYWSVDCSGRYCGNTSQNA
                     WSTELFPILPSIYLLGIAAAVLILVQRFQGPAAANRQVLGLRLDQWGIAFAVAALWTSI
                     WALGGGPSIPGYGHGFGAWLGLISLIVLAGAAAAAPLVPALKAPLVTDRPAAGPYQGGY
                     PMPGQPGHPGAPGQPGQYGYPGQAHDPAFGAQPVPGGYGYPAAGQPVQPHDAGAPAPQP
                     TPAAAQQPAAPAADFQPFWFAVPAPRQLAPKDNPAGAPVGELVPGTWYLAVEQRGAALV
                     AQLADGTQGVLADTAGIQRG"
     gene            complement(2702..3688)
                     /locus_tag="O1G21_RS26760"
                     /old_locus_tag="O1G21_26760"
     CDS             complement(2702..3688)
                     /EC_number="3.5.1.28"
                     /GO_function="GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA]"
                     /GO_process="GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003982946.1"
                     /locus_tag="O1G21_RS26760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_26760"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_270147206.1"
                     /transl_table=11
                     /translation="MTGPTSRPPRRSALLRATTVVAAVVPLCTAGWFGWRALDDSGPAG
                     ASAAASPGAVVSTSQAPGTPMAPPAGSTPTGATPTGTPTETSTPTAETPTPETPTAAPP
                     ADLTGRTIVLDPGHNPGNFAHPTEINRQVDIGNAHKECDTTGTETDAGYTEADYTLDVT
                     RRARALLTARGAKVVFTQDGDRPWGPCVDERARAGADAHADVAVSVHGDGGPASGSGFH
                     VIMPARVVAGKADNSAIVEPSHRLGLLLRDRFHAATGEPYADYVADEGLDTRSDLGGLN
                     LSAVPKVFIECGNMRNSADARRMTDPQWRQQAAQGIADALTAFLTTH"
     gene            complement(3696..4973)
                     /locus_tag="O1G21_RS26765"
                     /old_locus_tag="O1G21_26765"
     CDS             complement(3696..4973)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O1G21_RS26765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O1G21_26765"
                     /product="hypothetical protein"
                     /protein_id="WP_270147207.1"
                     /transl_table=11
                     /translation="MTDQHNTAPAVWDPTARGGAGGWVRNPQHPDAGSAPGEPPAPPTA
                     GAVGDQGPPLGARPYLSTAPGFGPPPDMSAPAPAPTPMPTPMPATDPGPGAPTTALPRV
                     APPPPGAPPSAGPPAPTPFPSHATPQDRGSQGGQLPGPGYVYPPPPTAGPYQQAPYQQP
                     PYPAQPDYPTAQPLDDEDEDDRDRPADRRTPLLIGFAVLLVLAVGGGLLYATTGNDGGK
                     NDQAAPAPSAATTTDSGNPPPAPAPTGTDAAPSATATPSGSPSPTATGAGPNAKAQAQA
                     LDALLTEGGNARAQIGNAVAKVTSCPAKADIESAAQVFDGGAKQRDGLLGKLGKLSVTD
                     LPGGTDAVNSLKSAWQLSADVDRAYASWARAVAAQGCSGTAPSTADKKHADELNPQATQ
                     AKNDFLNKWKPIATTYGLTPPTSDRI"
     gene            complement(5182..5835)
                     /locus_tag="O1G21_RS26770"
                     /old_locus_tag="O1G21_26770"
     CDS             complement(5182..5835)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007263840.1"
                     /locus_tag="O1G21_RS26770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_26770"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_270147209.1"
                     /transl_table=11
                     /translation="MSDLLEGARPAPEVLAAFEAATGFMPVDEGLALYAAAVAAARRTG
                     LPVLEIGTYCGRSAVLLAAAAREAGTVALTVDHHRGSEEQQPGWEYHDPTLVDPEVGRM
                     DTLPRFRRTLHAAGLEEHVVALVGRSPQIAALWGRPLALVFIDGGHTDEHATGDYEGWA
                     PHLAPEGLLVVHDVFPDPADGGQAPYRVYLRALAEGFEEVSVTGSLRVLRRTAA"
     gene            6061..7143
                     /locus_tag="O1G21_RS26775"
                     /old_locus_tag="O1G21_26775"
     CDS             6061..7143
                     /NRPS_PKS="Domain: PKS_ER (12-289). E-value: 7.9e-13.
                     Score: 40.1. Matches aSDomain:
                     nrpspksdomains_O1G21_RS26775_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018511765.1"
                     /locus_tag="O1G21_RS26775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_26775"
                     /product="alcohol dehydrogenase catalytic domain-containing
                     protein"
                     /protein_id="WP_270147211.1"
                     /sec_met_domain="ADH_N (E-value: 3.6e-27, bitscore: 93.2,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 3e-25, bitscore:
                     87.6, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAAVLHKTGQDTLDVREDVTAVGFGPGTVRVRMRAASLCHSDLS
                     AMSGVLPQPAPFVPGHEGAGDVVEVGEGVTGVAPGDRVVLCWMPPCGRCAHCDRGRGHL
                     CVASLRRLGAPGFRLAEDGTEASGFYGTGAFAEEVVVAADAVIKVPADLPYEAAALIGC
                     GVTTGIGAAVNTARVEPGSTVAVIGAGGVGVATVQGARVCGAARITVVDPVASRRERAL
                     AFGATEAIAPEELKAAAKGLPGGGFDYVFEAVGRAATVRAGYDAARRGGAVVVIGAGAQ
                     DDLAQFTMGELFFNEKRLLPSLYGGAPVARTVGLVVDLWRAGRIDLDGMITHRVGLADV
                     NLAIEQMRGGEALRTVVSLG"
     aSDomain        6097..6927
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_O1G21_RS26775_PKS_ER.1"
                     /evalue="7.90E-13"
                     /label="O1G21_RS26775_PKS_ER.1"
                     /locus_tag="O1G21_RS26775"
                     /protein_end="289"
                     /protein_start="12"
                     /score="40.1"
                     /tool="antismash"
                     /translation="TLDVREDVTAVGFGPGTVRVRMRAASLCHSDLSAMSGVLPQPAPF
                     VPGHEGAGDVVEVGEGVTGVAPGDRVVLCWMPPCGRCAHCDRGRGHLCVASLRRLGAPG
                     FRLAEDGTEASGFYGTGAFAEEVVVAADAVIKVPADLPYEAAALIGCGVTTGIGAAVNT
                     ARVEPGSTVAVIGAGGVGVATVQGARVCGAARITVVDPVASRRERALAFGATEAIAPEE
                     LKAAAKGLPGGGFDYVFEAVGRAATVRAGYDAARRGGAVVVIGAGAQDDLAQFTM"
     CDS_motif       6622..6654
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_O1G21_RS26775_0001"
                     /evalue="2.30E-01"
                     /label="PKSI-ER_m5"
                     /locus_tag="O1G21_RS26775"
                     /protein_end="198"
                     /protein_start="187"
                     /score="4.5"
                     /tool="antismash"
                     /translation="GAGGVGVATVQ"
     gene            complement(7231..7404)
                     /locus_tag="O1G21_RS26780"
                     /old_locus_tag="O1G21_26780"
     CDS             complement(7231..7404)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O1G21_RS26780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O1G21_26780"
                     /product="hypothetical protein"
                     /protein_id="WP_270147212.1"
                     /transl_table=11
                     /translation="MSDTLTDTTGPAITGTDADEKTAEDTASHGRHRGGSASDDTPGAD
                     PHGRHRAAGAQG"
     misc_feature    complement(7407..7418)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.41"
                     /tool="antismash"
     gene            complement(7724..7867)
                     /locus_tag="O1G21_RS26785"
                     /old_locus_tag="O1G21_26785"
     CDS             complement(7724..7867)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF038147.1"
                     /locus_tag="O1G21_RS26785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_26785"
                     /product="VenA family class IV lanthipeptide"
                     /protein_id="WP_270147213.1"
                     /transl_table=11
                     /translation="MENMVDFETDLAALQDLPETESVELTGHGSGCQYTCLVLTCLIFT
                     NS"
     gene            complement(8013..10004)
                     /locus_tag="O1G21_RS26790"
                     /old_locus_tag="O1G21_26790"
     CDS             complement(8013..10004)
                     /NRPS_PKS="Domain: Abhydrolase_1 (433-550). E-value:
                     2.2e-11. Score: 35.8. Matches aSDomain:
                     nrpspksdomains_O1G21_RS26790_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012546.5"
                     /locus_tag="O1G21_RS26790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_26790"
                     /product="S9 family peptidase"
                     /protein_id="WP_270147214.1"
                     /sec_met_domain="PF00561 (E-value: 5.5e-08, bitscore: 31.6,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_S9 (E-value: 1.5e-16, bitscore:
                     59.4, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVATRTTTQALRRLSFAFAADGSHAACLASAADSGWYVESWRLP
                     PDGSAAAPAALPLPGNRSESLRSQLVALPDGSVLVCRHDGERHDLVRLSYGENGTVEEQ
                     LATLRMPGLRLLALPVPPGADPRTPVAIALGTDTRPATTAWLVRVDGSEPVRVAEIPGL
                     HGGGAWLDHAGALLALDRVAGGLVRSVVLDLRSGITTPLLEIGEHSNDRLVLFDPDSRF
                     AMVRSDAPGTDRLGWGVLGGGEPLRFPERLHVTGMFLRPVALRQAADGPRVAVQIDHGA
                     GSALALWRPGVGRLDPLPVPPGRLGAVGHWDEAGLRIPYSSPDHPAALATLDVDALLAH
                     GPAPAGSAPIPLPLQLAPLGSGLPGPWRDTALPWQPGGPRSSPAPPAGWRLDGSTPPGD
                     GGRWQPAQSLELAGPAGPLEAVVYGGDAWLSSPHLVLALHGGPADAWRLEFDPALQRMA
                     AEGLAVVAPNQRGSTGYGVPHALAIRGAWGGPDLDDVLYLLEGIAGQRAALGLEPPALF
                     GVSYGAFLALLAAAHAPAEQVARCAVVAPFLSGARLLAEAAPPVRALTTRLGGGEPVLD
                     ARGPRDVLQLAHRLSAPLLVVHGNRDEVVPVSQSRSLRHELLRIGRVEGADFRYVEAAG
                     SGHEVLAEEGAAVLHELLAAFLRTGRPG"
     aSDomain        complement(8355..8705)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_O1G21_RS26790_Abhydrolase_1.1"
                     /evalue="2.20E-11"
                     /label="O1G21_RS26790_Abhydrolase_1.1"
                     /locus_tag="O1G21_RS26790"
                     /protein_end="550"
                     /protein_start="433"
                     /score="35.8"
                     /tool="antismash"
                     /translation="LVLALHGGPADAWRLEFDPALQRMAAEGLAVVAPNQRGSTGYGVP
                     HALAIRGAWGGPDLDDVLYLLEGIAGQRAALGLEPPALFGVSYGAFLALLAAAHAPAEQ
                     VARCAVVAPFLSG"
     gene            complement(10001..13018)
                     /gene="lanL"
                     /locus_tag="O1G21_RS26795"
                     /old_locus_tag="O1G21_26795"
     CDS             complement(10001..13018)
                     /codon_start=1
                     /gene="lanL"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038150.1"
                     /locus_tag="O1G21_RS26795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_26795"
                     /product="class IV lanthionine synthetase LanL"
                     /protein_id="WP_333493496.1"
                     /sec_met_domain="Pkinase (E-value: 2e-20, bitscore: 72.1,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.9e-33, bitscore:
                     114.5, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWWRMGAGTSLRTAVGGGSAGHGPDDAAGGWPEAARAALAGAGGR
                     GGGGAWEVTVGGFWCTARPSASSPLPEQGWKLHVSAASMVGGEVLAAVLRVLAVDPCSF
                     KFAAAEERLRELNSRNSERGSAGKFITVYPADDAQFQRLAAELDRVTAGLPGPVVLSDR
                     PYRPGSRVHYRYGAFAARAELGNDGEYRSVLRGPGGERTEDVRGGSYRAPGWVRDPFAP
                     PNARERGSGGGGGAGVLLAGRYAVTAAVRHGAKGGVFLGRETASGAEVVVKQARAHIEV
                     DRAGTDARDALRHEAALLARLDGQEVVPRAVELIEQDDSLFLVQERIAGQPLGSWVAAR
                     LRRDGSPDVDWAEAGPVAHGLLDLVERVHAQGLVLRDLSPGNVMVRPDGSLRLVDLELA
                     AETGRRAGTAGTPGYRAPEQGRLAPAGSSLAAPAVDLYALGGLLFLLATGHDPLLPEDL
                     PQARPVAERLGRWLALAARSGATARRLAPVVLGLRAEEPAARWGVARAREALGGRAGRA
                     GADDAAGRPDGPAAGSTRLSGRRGGSGPHPPGPASTAVVAPLWHAVPRPGGDPAPSDVP
                     ADTPALDRLLHDGLRHLAAGATPERSDRLWPVVPAGERTDPCNVQHGAAGVLAVLARAV
                     ATDGLPAEVRAEAARTARTAADWIERRVAAEPVVLPGLHFGRSGTAWALLDAARALGDD
                     AAAERAAALARRAPVEWPNPDVCHGAAGAGFTQLRFAADHFGEGFAEDSRAVFADRAAR
                     CARALLAAARQEPYGTVWPVPGDFDSALAGITHLGFAHGVAGVGAFLLAAAGATDHRAL
                     REDCTAAALAAGRTLGATVRWGDAERSTAWWPQSAGDPEHLRLSHWCSGSSGAGSFLLR
                     LWRATGDAEALGLARAAGRAVLAGRWHSGVSACHGSAGDGEYLLDLAEATGEREFRTSA
                     RELADVITARSALRDGLLVLPDETGTGCAAGYGTGTAGPLAFLLRLRHGGPRLWLDPVS
                     PVRRQLPHHSSGVSEA"
     misc_feature    complement(12809..12811)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    13097..13111
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.6"
                     /tool="antismash"
     misc_feature    13164..13177
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.7"
                     /tool="antismash"
     misc_feature    13165..13179
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 13.75"
                     /tool="antismash"
     gene            13457..14293
                     /locus_tag="O1G21_RS26800"
                     /old_locus_tag="O1G21_26800"
     CDS             13457..14293
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0051540 - metal cluster binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135535.1"
                     /locus_tag="O1G21_RS26800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_26800"
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="WP_270147217.1"
                     /transl_table=11
                     /translation="MPKLSDVITALEEVYPPQWAESWDAVGLVCGDPQAEVSRVLFAVD
                     PVQAVVDEAVEWGADLVVTHHPLYLRGTTSVAATTFKGRVVHTLISNGIALHVAHTNAD
                     HADPGVSDALAEAVGLRVTGPLVPDPTDPLGRRGSGRIGLLETPLTLSAFAAQVASGLP
                     ATAAGVRVSGDPNRLVSRVAVCGGSGDGFLADVRAAGVDAYVTADLRHHPASEATEAAP
                     VALVDAAHWATEWPWLGLAERALLAAADQRGWAVETKVSHRVTDPWTAHAPMSFTA"
     misc_feature    complement(13467..13481)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.72"
                     /tool="antismash"
     gene            14317..15060
                     /locus_tag="O1G21_RS26805"
                     /old_locus_tag="O1G21_26805"
     CDS             14317..15060
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003989855.1"
                     /locus_tag="O1G21_RS26805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_26805"
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="WP_270147219.1"
                     /transl_table=11
                     /translation="MNAAPADQIRLLDLQAIDSKLDQLAHRRRSLPEHAEIEKATADHT
                     ALKDLVIAAEAQKGDTARELTKAEQDVEQVRARAARNQQRLDSGAITSPKDLENLQHEI
                     GSLAKRQGDLEEVVLEIMERQESANTRVEELSARLEHSTVILKEAEGRRDAAFAEIDAE
                     ADKVKRDRETVAAVIPADLLKLYAKLRETQGGVGAARLYQRRCEGCRTEFSITELNAIK
                     AEPADKVVRCENCSRILVRTADSGV"
     gene            15065..16207
                     /locus_tag="O1G21_RS26810"
                     /old_locus_tag="O1G21_26810"
     CDS             15065..16207
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018539132.1"
                     /locus_tag="O1G21_RS26810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_26810"
                     /product="bifunctional RNase H/acid phosphatase"
                     /protein_id="WP_270147221.1"
                     /transl_table=11
                     /translation="MAARFIVEADGGSRGNPGPAGYGAVVRDGDTGQLVAEAAEFIGHA
                     TNNVAEYRGLIAGLRAARELDPDASVDVRMDSKLVVEQMSGRWKIKHPDMQPLAAEARA
                     VFPHGRVTYTWIPRERNKDADRLANEAMDAGRDGRQWEPRKPVGAVAVTEEPPLEQAVP
                     KAGWAAPADLGTPTTFVLLRHGETPLTPEKRFSGSGGTDPELSDKGRWQAERVAEALAA
                     RGSIQAVVASPMRRTRQTAEIVAARLGLEVRYEDGLREVDFGAWEGLTFAEVRERYPDD
                     LTAWLGSAKAKPTGSTESFTTLTHRAGVTRDKILARYPGKTVLVVSHVSPIKTLVRLAL
                     GAPPDSMYRMELSAASICAVQYYADGNASLRLLNDASHLR"
     gene            complement(16245..17030)
                     /gene="yaaA"
                     /locus_tag="O1G21_RS26815"
                     /old_locus_tag="O1G21_26815"
     CDS             complement(16245..17030)
                     /codon_start=1
                     /gene="yaaA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018892126.1"
                     /locus_tag="O1G21_RS26815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_26815"
                     /product="peroxide stress protein YaaA"
                     /protein_id="WP_270147223.1"
                     /transl_table=11
                     /translation="MLVLLPPSEGKAASGDGEPVALERLSLAGLTAARGAVLDALVGLC
                     RGDEDTAAEVLGLTPGLRGEIAKNAGLPTAGARPAAEVYTGVLFDNLGLATLDAAAYDR
                     AERSLLVFSGLWGAVRISDRIPSYRCSMGVKLPGLGALGAYWRSATASVLPEVADGLVL
                     DLRSSAYAAAWKPAGEVASRTATVRVLQERDGKRTVVSHFNKATKGRIVRDLLVAGTEP
                     KTPTELMDALLALGHHVELAAEGTARKPWQLDVVVTEVH"
     gene            complement(17041..17493)
                     /locus_tag="O1G21_RS26820"
                     /old_locus_tag="O1G21_26820"
     CDS             complement(17041..17493)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024559.5"
                     /locus_tag="O1G21_RS26820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_26820"
                     /product="DUF3995 domain-containing protein"
                     /protein_id="WP_270147224.1"
                     /transl_table=11
                     /translation="MGAAVRVAGGAVSAALAVTGALHAVWAVTPWPLRTPEDFADTVVG
                     TGDGVPPAGACLAVAGLLGAASYLVGAEAGVLPQAGPRALRRAGVRAVAGVLVARGVAG
                     PVVFGRVSGRTERFRRLNVRYYSPLCVALGAGAAAVGWRGSSATKC"
     gene            17677..18012
                     /locus_tag="O1G21_RS26825"
                     /old_locus_tag="O1G21_26825"
     CDS             17677..18012
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O1G21_RS26825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O1G21_26825"
                     /product="hypothetical protein"
                     /protein_id="WP_270147226.1"
                     /transl_table=11
                     /translation="MTMRPLDLVPGDGEAVEESLSVRLPAGLPDETRQALEFALRAAAQ
                     AVMAGRVRVTEAATGSDTAELAFEVRQSELPEALTEGAPGKAERRAAMVARIRAANAET
                     LERLKDL"
     gene            18009..18383
                     /locus_tag="O1G21_RS26830"
                     /old_locus_tag="O1G21_26830"
     CDS             18009..18383
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019886729.1"
                     /locus_tag="O1G21_RS26830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_26830"
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="WP_270147228.1"
                     /transl_table=11
                     /translation="MTTEYLDLDDVTYLAGGPQNVRDLGGLLSAIARPQASLFGSDAYP
                     DLWTKAAALGQSLARNHPLVDRNKRTAFEAMLLFLDYNAEPYADPHPDDAVAFMLRLAT
                     GGYDDAIGLAAKDLKSLLGR"
     gene            18438..19913
                     /locus_tag="O1G21_RS26835"
                     /old_locus_tag="O1G21_26835"
     CDS             18438..19913
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0004540 - RNA nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017239016.1"
                     /locus_tag="O1G21_RS26835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_26835"
                     /product="RNB domain-containing ribonuclease"
                     /protein_id="WP_270147229.1"
                     /transl_table=11
                     /translation="MPRRKLRVKAADSARINTELTELRTHLEIHTEWPEAVLAEAEEAA
                     EHPWLPEHDATDLPLFTVDPPGSRDLDQAMHLSHRPGGGYRVHYAIADVAAFVRPGGAI
                     DAEARRRVETLYFPDHRVPLHPTRISEDAASLLPGEPRPALLWQLDLDADGAVVLADVR
                     RALVRSHRRLDYAAVQRAVDLGGADEQLALLATVGRLREEQERARGGISLPVPEQEVEE
                     TLHGYVLGYRAPSPADGWNAQISLLTGMAAAELMLDAGVGLLRTLPAAPAAAYERLRRI
                     AAALDVDWPQAVPYPELIRSLDPEVPLNAAFLNACTGLLRGAGYHAFDESRGLPAPAEP
                     GHAALAAPYAHCTAPLRRLGDRFAQEVCVAVAAGEDVPDWAREALPAVPALMAGGDRRA
                     GEVERACVDLVEAELLVGREGEDFAAVVIEVDERRPGSGTVQLREPAVRARCDGAASGS
                     PDGVAARLPLGRMIDVRLTTADPATRTVRFAAV"
     gene            20083..21594
                     /locus_tag="O1G21_RS26840"
                     /old_locus_tag="O1G21_26840"
     CDS             20083..21594
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014179819.1"
                     /locus_tag="O1G21_RS26840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_26840"
                     /product="MFS transporter"
                     /protein_id="WP_270147231.1"
                     /transl_table=11
                     /translation="MPDPQPPAAIPAARVPVAGRRRRLLVLAICCLSLFIVGLDNTVVN
                     IALPVIQKDLGAPASGLQWIIDAYTLVLASLLMLFGSVADRFGRRRVFQIGLTCFALGS
                     LLCSLAPSLEWLVVFRALQAVGGSMLNPVAMSIITNTFTDPKERARAIGVWGGVVGISM
                     ALGPLLGGFLVDGAGWPSIFLINVPVALLAILLTIRYVPESRAPRPRRLDPVGQLLMIV
                     LLGCGTAAIIEGPGNGWTSPLILALAAAAVAALIAFPLWERRVAEPLVDPRFFASAPFT
                     GATVTAVCAFAALGGFLFLNTLYLQDVRHYGPVEAGLWTLPMAGLMLVCAPLSGRIVGS
                     RGPRLPLVVAGLGLAASDLLLTRLTADSPAALLLVAYALFGFGFGMVNAPITNAAVSGM
                     PRSQAGVAAAVASTSRQVGQSLGVAVIGTVVTSAVVGPLATGFAPASHAGWWILVGLGA
                     AILALGVLTTGTWATDTAARVAARLGAEPPVARSGVREAPPERLP"
     ncRNA           21608..22005
                     /db_xref="RFAM:RF00010"
                     /gene="rnpB"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="O1G21_RS26845"
                     /ncRNA_class="RNase_P_RNA"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /old_locus_tag="O1G21_26845"
                     /product="RNase P RNA component class A"
     gene            21608..22005
                     /gene="rnpB"
                     /locus_tag="O1G21_RS26845"
                     /old_locus_tag="O1G21_26845"
     gene            complement(22212..22514)
                     /locus_tag="O1G21_RS26850"
                     /old_locus_tag="O1G21_26850"
     CDS             complement(22212..22514)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O1G21_RS26850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O1G21_26850"
                     /product="hypothetical protein"
                     /protein_id="WP_270147233.1"
                     /transl_table=11
                     /translation="MHLSQAYTLLGDTGSAHQAQEDALALTDSPSVMVRALLAVDTAAC
                     LHVDGDPSGAAEMASGVWERLPATYREGLIRSRAETLHRQLTGRPYALLGEALAS"
     misc_feature    22810..22825
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.34"
                     /tool="antismash"
     misc_feature    22812..22826
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.98"
                     /tool="antismash"
     misc_feature    complement(22859..22873)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.36"
                     /tool="antismash"
     misc_feature    complement(22940..22955)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.61"
                     /tool="antismash"
ORIGIN
        1 gagcacatac ccgacgacaa gggcgtgctc aacgagatgt tccgcgtcct caagccgggc
       61 ggcctgctcg ccgtcaccgt gccgcgctgg ctgccggaga agatctgctg ggcgctgtcc
      121 gacgagtacc acgaggtcga gggcggtcac atccggatct accggggtga cgagctgctc
      181 ggcaagctca aggacgccgg cctggagccg tacggcaccc accacgcgca cgcgctgcac
      241 tcgccgtact ggtggatcaa gtgcgccgtc ggcgtggaca acgacaaggc gctgccggtc
      301 aaggcgtacc accagctgct ggtctgggac atcgtcggga ccccggtgat cagcaccctc
      361 accagggccg ccgagaaggc gctcaacccg gtcatcggca agagcttcgt cgcctacgcc
      421 gccaagccga accgcacgga gcccgggcag gcgggcgcat gacccccgcc gtccccgagg
      481 tgctgctgct cgacggggtg ctggacgccg agcaggcggc cgacaccgtc cgcagcatcc
      541 tggccgagca gcgccccgac ggcgccatcc cgtggttcgc cggccaccac ctcgacccgt
      601 gggaccacac cgaggccgcg atggccctcg acaccgccgg cgagcacgcc gccgccgagg
      661 ccgcctaccg ctggctcgcc gcgcagcaga acccggacgg ttcctggtac gccgcgtaca
      721 ccgacggtgt ggtcaccgac cgggccaagg agagcaactt ctgcgcgtac atcgcggtcg
      781 gggtctggca ccaccacctc agcgccggcg acgacgcctt cctggagtgg atctggccgg
      841 tggtccggcg ggcgctggac ttcatcgtcg gcctgcggct gcccgacggc ccgatcgcct
      901 ggcgggtcga cgaggacggc gccgcgaccg gggaggcgct gctcaccggc tcgtccagca
      961 tcctgcacgc gctgcgctgc ggcctggcca tcgccgacta cctggaggag ccgcagcccg
     1021 actgggagct cgcggcaggc cggctgcggc acgccatcgc ccaccacccc gagcggttcc
     1081 tggacaaggg ccgctactcg atggactggt actacccggt gctcggcacc ggcctgcgcg
     1141 gcgacgcggc gctggcccgg atcgagcggg actgggaccg cttcgtcgtc cccggcctcg
     1201 gcgtgcgctg cgtcagcgac cgcccgtggg tgaccggcgg ggagagtgcc gaactggccc
     1261 tcgcgctctg ggcgatcggc cagtccgacc gcgcggtgga catcctgcgc tggatccaga
     1321 agcacctgcg gcaccaggac ggctcgtact ggaccgggta cgtcttcgag gacgacgcga
     1381 tctggcccga ggagcgcacc acctggacgg ccggggcgct gctgctcgcg gtggccgcgc
     1441 tcggcgggga cccggcgacc gtcgcggtct tcggcgggga gcagctgccc gccgggctgg
     1501 tggtccagga ctgctgctga gcccacgaag accgaagggg cgggaccggt gatccggtcc
     1561 cgccccttcg gcgtgctcga cgggcgtcag ccgcgctgga tgcccgcggt gtcggccagc
     1621 acgccctggg tgccgtccgc cagctgggcg accagggccg cgccgcgctg ctcgacggcc
     1681 aggtaccagg tgcccggcac gagctcgccg accggggcgc cggccgggtt gtccttcggg
     1741 gccagctggc gcggggccgg gacggcgaac cagaacggct ggaagtccgc cgccggggcg
     1801 gccggctgct gggcggcggc cggggtcggc tgcggggccg gggcgccggc gtcatgcggc
     1861 tgcaccggct ggccggcggc cgggtagccg tacccgccgg ggaccggctg ggcgccgaag
     1921 gccgggtcgt gggcctggcc cgggtagccg tactggccgg gctgaccggg ggcacccggg
     1981 tgaccgggct gacccggcat cgggtagccg ccctggtacg ggccggcggc cgggcggtcg
     2041 gtgaccagcg gggccttcag cgcgggcacc agcggcgcgg ccgcggccgc accggccagc
     2101 acgatcagcg agatgaggcc gagccaggcg ccgaagccgt ggccgtagcc ggggatcgac
     2161 gggccgccgc ccagcgccca gatcgaggtc cacagcgccg cgacggcgaa cgcgatgccc
     2221 cactggtcca gccgcaggcc gagcacctgg cggttggcgg cggcggggcc ctggaagcgc
     2281 tgcaccagga tcaggacggc ggcggcgatg cccagcaggt agatcgaggg caggatgggg
     2341 aacagctcgg tgctccacgc gttctgcgag gtgttcccgc agtaccggcc gctgcagtcc
     2401 acggaccagt aaggcaggaa ggaggcgatg aacagcagga cggccgcgcc tgcgacggcg
     2461 gcgtctcccc tggtgagagc gcgcagattc acttacgttc ccctcgttga cgtgtcgtgg
     2521 acggtgcttc gcgcggtcgg gctgaccggc cgaaactccc gaacggacca gaagcctagg
     2581 cccaaccgtc ctgccggtgc acggcgggac cgggaacggg tcgaagtcgt tgcaaaccgt
     2641 gcgggcccgg tggtgcgtcg tccaccgggc ccgcacgtcc caactccctt gccgggcccg
     2701 ctcagtgcgt ggtcaggaag gcggtcagcg cgtcggcgat cccctgggcg gcctgctgcc
     2761 gccactgagg gtccgtcatc cgtcgggcgt ccgcggagtt gcgcatgtta ccgcactcga
     2821 tgaacacctt gggaaccgcg gagaggttga ggccgcccag gtcggagcgg gtgtccaggc
     2881 cctcgtccgc gacgtagtcg gcgtacggct cgccggtcgc ggcgtggaag cggtcgcgca
     2941 gcagcaggcc gaggcggtgc gagggttcga cgatcgcgga gttgtccgcc ttgccggcga
     3001 ccaccctggc gggcatgatc acgtggaagc cgctgccgct cgccggaccg ccgtcgccgt
     3061 gcaccgagac cgcgacgtcg gcgtgcgcgt cggcgcccgc cctggcgcgc tcgtccacgc
     3121 acgggcccca ggggcggtca ccgtcctggg tgaacaccac cttggcgccc cgggcggtca
     3181 gcagggcgcg ggcccggcgg gtgacgtcca gggtgtagtc ggcctcggtg tagccggcgt
     3241 cggtctcggt gccggtggtg tcgcactcct tgtgggcgtt gccgatgtcg acctgacggt
     3301 tgatctcggt ggggtgggcg aagttgccgg ggttgtggcc ggggtcgagc acgatggtgc
     3361 ggccggtgag gtcggcgggg ggcgccgcgg tgggggtctc cggggtgggg gtttccgcgg
     3421 tgggggtcga cgtctcggtg ggcgtgcccg tcggcgtggc gcccgtcggg gtgctgccgg
     3481 ccggcggcgc catcggggtg cccggggcct ggctggtgga gacgacggcg ccgggcgacg
     3541 cggcggccga ggcgcccgcc gggccggagt cgtccagggc ccgccagccg aaccagcccg
     3601 ccgtgcacag cggtacgacc gcggccacca cggtggtggc gcgcagcagg gcggaacggc
     3661 ggggcggtcg ggaggtcggg ccggtcacgg gtggttcaga tcctgtccga ggtgggcggg
     3721 gtgagaccgt aagtggtcgc gatcggcttc cacttgttca ggaagtcgtt cttcgcctgg
     3781 gtggcctgcg ggttgagttc gtccgcgtgc ttcttgtccg ccgtgctcgg cgcggtgccg
     3841 gagcagccct gggcggcgac ggcgcgcgcc cagctcgcgt acgcccggtc gacgtcggcg
     3901 gacaactgcc aggcggactt gagcgagttc accgcgtccg tgccgccggg caggtccgtg
     3961 acgctcagct tgccgagctt gcccagcagg ccgtcgcgct gcttggcacc gccgtcgaag
     4021 acctgcgccg cgctctcgat gtcggccttc gcggggcaac tggtcacctt ggccaccgcg
     4081 ttgccgatct gggcccgggc gttcccgccc tcggtgagca gggcgtccag tgcctgggcc
     4141 tgggccttgg cgttggggcc ggcgccggtc gcggtcgggg agggcgaacc ggagggcgtg
     4201 gccgtggcgc tcggcgcggc gtccgtaccg gtgggcgcgg gggcgggcgg cgggttgccg
     4261 gagtcggtcg tggtggcggc cgaaggggcg ggcgcggcct ggtcgttctt gccgccgtcg
     4321 ttgccggtgg tcgcgtacag caggccgccg ccgaccgcca ggaccagcag caccgcgaag
     4381 ccgatcagca gcggggtcct gcggtcggcc gggcggtccc ggtcgtcctc gtcctcgtcg
     4441 tcgagcggct gggcggtcgg gtagtccggc tgggcggggt acgggggctg ctggtacggg
     4501 gcctgctggt acgggccggc cgtgggcggc ggcgggtaga cgtagccggg gcccgggagc
     4561 tgcccgccct gggagccgcg gtcctgcggg gtcgcgtggg aggggaacgg cgtgggcgcg
     4621 ggcgggcccg ccgagggcgg ggcgcccggg ggcggcgggg cgacccgggg gagggcggtg
     4681 gtgggcgccc cggggcccgg gtccgtggcg ggcatcgggg tgggcatcgg ggtgggcgcg
     4741 ggggccggtg ccgacatgtc cggcggcggg ccgaagcccg gggcggtgga caggtacggg
     4801 cgggcgccca gcggcggtcc ctgatcgccg accgcgcccg cggtgggggg cgccggcggt
     4861 tcgccggggg cggacccggc gtccgggtgc tgcggattgc ggacccagcc gcccgcgccg
     4921 ccgcgcgcgg tcgggtccca gaccgccgga gcggtgttgt gctggtccgt catgtgccgc
     4981 tagcccccac cgtccgccga tgctctgcct ggtgctgccg cccgtgccgc agctgcctgg
     5041 tgctgcgcgg ccaccgtacc gttcgagcac gcgcccgaca gccccggcac gacgttagag
     5101 catccgggcg gggctgtggg ggcgatctcg cggggtggtc ggggcggtcg gggcggggcc
     5161 gtcagggccg gtccgggtcg gtcaggcggc ggtccggcgc agcacgcgca gcgagccggt
     5221 caccgagacc tcctcgaagc cctcggccag cgcccgaagg tacacccggt acggggcctg
     5281 gccgccgtcc gccgggtccg ggaacacgtc gtgcaccacc agcaggccct ccggcgccag
     5341 gtgcggtgcc cagccctcgt agtcgccggt ggcgtgctcg tcggtgtgcc cgccgtcgat
     5401 gaagaccagg gccagcggcc ggccccacag cgcggcgatc tgcggcgagc ggccgaccag
     5461 cgcgaccacg tgctcctcca gcccggcggc gtgcagggtg cgacggaacc ggggcagggt
     5521 gtccatccgc ccgacctccg ggtccaccag ggtcgggtcg tggtactccc agccgggctg
     5581 ctgctcctcc gagccgcggt ggtggtccac ggtcagcgcg accgtcccgg cctcccgggc
     5641 cgcggccgcc agcaggaccg ccgagcgccc gcagtaggtg ccgatctcca gcaccggcag
     5701 cccggtgcgc cgggccgccg ccaccgccgc cgcgtacagc gcgagcccct cgtccaccgg
     5761 catgaacccg gtggccgcct cgaacgccgc cagcacctcc ggcgccggac gggcgccctc
     5821 cagcaggtcg gacatgcggt gctcctcggg ttcggacggc ggacggacgt gctcggaccc
     5881 tactcgacgg tagccgcggc ggcggtcccg ggtggggcga ttcccgtatg cagggccttt
     5941 cgtggagccg ctggtcgggc gggtggtccg gggtggtttt ggaacgcgtt ccagtgagtc
     6001 gccggaggcc gtgccagaat cgccccgacc cttgacccga ggcacaccgg gagcagcccc
     6061 atgcgcgcag ccgttctgca caagaccggc caggacaccc tcgacgtccg ggaggacgtc
     6121 accgcggtcg gtttcggacc gggcaccgta cgggtccgga tgcgcgccgc cagcctgtgt
     6181 cactcggacc tctccgcgat gagcggcgtc ctgccgcagc ccgcgccgtt cgtccccggg
     6241 cacgagggcg ccggggacgt cgtcgaggtc ggcgagggcg tgaccggcgt cgcccccggg
     6301 gaccgggtgg tgctctgctg gatgcccccc tgcggccgct gcgcccactg cgaccgcggc
     6361 cgcggccacc tgtgcgtcgc cagcctgcgg cggctcggcg cgcccggctt ccggctggcc
     6421 gaggacggca ccgaggcctc cggcttctac ggcaccggtg ccttcgccga ggaggtggtg
     6481 gtcgccgccg acgccgtcat caaggtgccg gccgacctcc cgtacgaggc cgccgcactc
     6541 atcggctgcg gggtgaccac cggcatcggc gccgcggtca acaccgcccg ggtcgagccc
     6601 ggttccacgg tcgcggtgat cggcgcgggc ggcgtcggcg tggccaccgt ccagggtgcc
     6661 cgggtctgcg gtgccgcccg gatcaccgtc gtcgacccgg tggcgtcccg ccgcgagcgg
     6721 gcactcgcct tcggcgccac cgaggcgatc gcccccgagg agctgaaggc cgccgccaag
     6781 ggcctgcccg gcggcggctt cgactacgtc ttcgaggcgg tcggccgcgc ggccaccgtc
     6841 cgggccggct acgacgcggc ccggcgcggc ggcgcggtcg tcgtcatcgg cgcgggcgcg
     6901 caggacgacc tcgcgcagtt caccatgggc gagctgttct tcaacgagaa gcggctgctg
     6961 ccctcgctgt acggcggggc gccggtggcc cgcaccgtcg gactggtcgt ggacctgtgg
     7021 cgggccggac ggatcgacct cgacgggatg atcacccacc gggtcgggct ggcggacgtg
     7081 aacctggcga tcgagcagat gcgcggcggc gaggcgctgc ggacggtggt ctcgctcggc
     7141 tagctctgtc ttcttccggg cccatgacgg gcgagggccc gccgggatgt gtcctcggcg
     7201 ggccctcgcg ggtgcggtcg ttcctcggga tcagccctgg gcgccggccg cgcggtggcg
     7261 gccgtgcggg tcggccccgg gggtgtcgtc ggaggcggag ccaccgcggt ggcgaccgtg
     7321 cgacgcggtg tcctcggccg tcttctcgtc ggcgtcggtc ccggtgatcg cggggccggt
     7381 ggtgtcggtg agggtgtcgg acatgagaaa tcgtcttccg tgcggagggt gcaggtcatc
     7441 ggcgcccgcc cggcgcctgc ggcacacggt cgggtccccg atcgggcgct cggtacgcgc
     7501 cacagccggt gatcgcggcc cgtgccccgg ccaccataac ggccgggacg gacgagatcc
     7561 tatcgacctc gtggggcgag tcccgccccg cccggggtgg ctgaccgacg ccttcgccgc
     7621 ccggcggccg accgcaccca gctgcgagaa gtcggtgcgg gaagaccggt gccgtccccg
     7681 cctgtccgga ccggcgggga cggcacccgt gggccgaacc tgatcagctg ttggtgaaga
     7741 tcagacaggt caggacgaga caggtgtact ggcagccgct gccgtggccg gtcagctcga
     7801 ccgactcggt ctccggcagg tcctgcagcg ccgcgaggtc ggtctcgaag tccaccatgt
     7861 tctccatggt cggatcctcc ccttgaggtg cgcccgcggc gatctgcctg cgggcatcgg
     7921 gtgttcgccc cgggcggcct ccatccgccg cgccgggggt cgtgccccgg gccgccgtgg
     7981 gcccgggagt ccgtggtgtg tgtggtgagg ggtcagcccg gtcggccggt ccgcaggaac
     8041 gcggccagca gttcgtgcag cacggcggcg ccctcctcgg cgagcacctc gtgtccggag
     8101 ccggccgcct cgacgtaccg gaagtccgcg ccctcgaccc gcccgatccg cagcaactcg
     8161 tggcgcagcg aacgggattg gctcaccggc accacctcgt cccggttgcc gtgcaccacc
     8221 agcagcggcg cgctcagccg gtgcgccagc tggagcacgt cgcgcggacc gcgggcgtcc
     8281 aggaccggct cgccgccgcc gagccgggtg gtcaacgccc gtacgggtgg cgccgcttcg
     8341 gcgagcagcc gggcgccgga caggaacggt gcgaccaccg cacagcgggc gacctgctcg
     8401 gcgggggcgt gcgcggccgc cagcagggcc aggaacgcgc cgtagctgac cccgaacagg
     8461 gcgggcggtt ccaggccgag tgcagcgcgc tgaccggcga tgccctccag caggtacagc
     8521 acgtcgtcca ggtccggacc gccccaggcg ccccggatcg ccagcgcgtg cggcaccccg
     8581 tagccggtgg agccgcgctg gttgggcgcg accacggcca gaccctcggc ggccatccgc
     8641 tgcagcgccg ggtcgaactc cagccgccag gcgtccgccg gtccgccgtg cagcgccagc
     8701 accaggtgcg ggctgctcag ccaggcgtcc ccgccgtaca ccacggcctc caaggggcct
     8761 gccgggcccg cgagttcgag gctctgcgcg ggctgccagc ggccgccgtc accgggcggg
     8821 gtgctgccgt ccaggcgcca gccggcgggc ggggcgggcg agctgcgcgg tccgccgggc
     8881 tgccagggca gtgcggtgtc ccgccagggg ccgggcaatc ccgagcccag cggggcgagt
     8941 tggagcggca gcgggatcgg ggccgatccg gccggagccg gtccgtgcgc cagcagggcg
     9001 tccacgtcca gggtggccag cgccgccggg tgatcggggg aggagtacgg gatccgcagt
     9061 cccgcctcgt cccagtgccc gaccgcgccc agccgcccgg gcggcaccgg cagcgggtcc
     9121 agccggccga cgccgggccg ccacagggcg agcgccgacc cggcgccgtg gtcgatctgc
     9181 accgcgaccc gggggccgtc cgccgcctgc cgaagcgcga ccggccgcag gaacatgccc
     9241 gtgacgtgca ggcgttccgg gaaccgcagc ggctccccgc cgcccagcac gccccagccc
     9301 agccgatcgg tgccgggcgc gtcgctgcgc accatcgcga agcggctgtc cgggtcgaac
     9361 agcaccagcc ggtcgttgct gtgctcgccg atctccagca gcggggtcgt gatgccgctg
     9421 cgcaggtcca gcaccacgct gcggaccagc ccgccggcca cccggtccag cgcgagcagc
     9481 gcgcccgcgt ggtccagcca ggcgccgccg ccgtgcaggc cggggatctc ggcgacccgt
     9541 accggctcgc tgccgtccac ccggaccagc cacgcggtgg tcgccgggcg ggtgtccgtg
     9601 ccgagggcga tcgccaccgg ggtgcgcggg tcggcgccgg gcggcaccgg gagcgccagc
     9661 aggcgcagtc cgggcatccg gagcgtggcc aactgctcct ccacggtgcc gttctcaccg
     9721 tacgagaggc ggaccaggtc gtgccgctcg ccgtcgtgcc ggcagaccag caccgagccg
     9781 tcgggcagcg cgaccagctg cgaacgcagg ctctccgagc ggttgccggg cagcggcagc
     9841 gcggccgggg cggccgctga accgtccggc gggaggcgcc aactctccac gtaccagccg
     9901 ctgtcggctg ccgaggccag gcaggccgcg tggctgccgt cggcggcgaa ggcgaagctc
     9961 agccggcgca gggcctgggt ggtggtgcgg gtggccacgt tcacgcctcg ctcaccccgc
    10021 ttgagtggtg ggggagttgc cgccggacgg gggagaccgg gtccagccag agccgggggc
    10081 cgccgtggcg gagccggagc aggaaggcca acggccctgc ggtgccggtg ccgtagccgg
    10141 cggcgcagcc ggtgccggtc tcgtcgggga ggaccagcag gccgtcccgc agtgcggagc
    10201 gggcggtgat cacatcagcc aactcccttg cgctggtgcg gaattcccgc tcgccggtgg
    10261 cctcggcgag atccagcagg tactcgccgt cgccggccga gccgtggcag gcgctcaccc
    10321 cgctgtgcca gcggccggcc agcacggccc ggccggcggc gcgggcgagg ccgagggctt
    10381 cggcgtcgcc ggtggcccgc cacagccgca gcaggaagct gcccgcgccg gaggagccgc
    10441 tgcaccagtg cgagagccgg aggtgctccg gatcgcccgc gctctgcggc caccaggcgg
    10501 tgctccgctc ggcgtcgccc caccgtacgg tcgcgccgag cgtccgcccg gcggcgagcg
    10561 cggcggccgt gcagtcctcg cgcagcgcgc ggtggtcggt cgccccggcg gcggcgagga
    10621 ggaaggcgcc cacgcccgcc acgccgtggg cgaagccgag gtgggtgatc ccggcgagtg
    10681 ccgagtcgaa gtcgccgggc accggccaga ccgtcccgta cggctcctgc cgcgcggcgg
    10741 cgagcagggc gcgggcgcag cgggcggccc ggtcggcgaa gaccgcgcgg gagtcttcgg
    10801 cgaagccttc gccgaagtgg tcggcggcga aacggagttg ggtgaaccca gcgcccgccg
    10861 cgccgtggca cacatcgggg ttgggccact cgacgggcgc ccgccgggcg agcgccgcgg
    10921 cccgttcggc cgcggcgtcg tcgcccagcg cgcgggcggc gtccagcagc gcccacgccg
    10981 tccccgagcg cccgaagtgc agcccgggca gaaccaccgg ctcggcggcg acccgccgtt
    11041 cgatccagtc cgcggcggta cgggccgtgc gggcggcctc cgcccgcacc tcggccggca
    11101 ggccgtcggt cgcgaccgcc cgggccagta cggcgagcac gcccgcggcg ccgtgctgga
    11161 cgttgcacgg gtcggtccgc tccccggcgg gcacgacggg ccacagccgg tcggaccgct
    11221 cgggcgtcgc gccggcggcg aggtgccgca ggccgtcgtg cagcaggcgg tcgagcgcgg
    11281 gggtgtccgc cggtacgtcg gagggcgccg ggtcgccgcc cggtcggggg acggcgtgcc
    11341 acagcggagc gacgacggcg gtggacgcgg ggccgggtgg gtgcgggccg ctgccacccc
    11401 ggcgcccact gagccgggtg cttcccgcgg cggggccgtc cggtcgcccg gccgcgtcgt
    11461 ccgctccagc ccgcccggcc cgcccgccca gggcctcccg ggcccgggcc accccccacc
    11521 gtgctgccgg ctcctccgcc cgcaggccca ggaccaccgg cgccagccgc cgcgccgtcg
    11581 cacccgaacg ggctgcgagg gcgagccagc gtccgaggcg ttcggcgacg ggccgggcct
    11641 gcgggaggtc ctcgggcagg agcgggtcgt gtccggtggc gagcaggaag agcagtccgc
    11701 cgagcgcgta caggtcgacg gccggggcgg cgaggctgga gcccgcgggt gcgagccggc
    11761 cttgttcggg ggcgcggtag ccgggggtgc cggcggttcc ggcccggcgg ccggtttcgg
    11821 cggcgagttc gaggtcgacc agtcgcaggc tgccgtccgg gcggaccatg acgttgccgg
    11881 gcgagaggtc gcgcagcacc agcccttggg cgtgcacccg ctcgaccagg tcgagcagcc
    11941 cgtgcgccac cggtccggcc tcggcccagt ccacgtcggg gctgccgtcg cgtcgcagcc
    12001 gggccgcgac ccagctgccg agcggctgtc cggcgatccg ttcctgcacc aggaagaggg
    12061 agtcgtcctg ctcgatcagt tcgacggcgc gcggtaccac ctcctgcccg tccagccggg
    12121 cgagcagcgc ggcctcgtgg cgcagcgcgt cgcgggcgtc cgtgccggcg cggtcgacct
    12181 cgatgtgggc gcgggcctgc ttgaccacga cctccgcgcc gctcgccgtc tcccggccga
    12241 ggaacacgcc ccccttggcg ccgtgccgca cggcggccgt caccgcgtag cgcccggcca
    12301 gcagcacccc ggccccgccc ccgcccccgc tcccgcgttc gcgcgcgttg gggggagcga
    12361 acgggtcccg cacccacccc ggtgcccggt acgacccacc gcgcacgtcc tcggtgcgtt
    12421 ccccgcccgg cccgcgcagc accgagcggt actccccgtc gttgccgagc tccgcccgcg
    12481 ccgcgaacgc gccgtagcgg tagtgcaccc ggctgcccgg ccggtacggc cggtcggaca
    12541 gcaccaccgg gccgggcagt ccggccgtca cccggtccag ctcggccgcc agccgctgga
    12601 actgcgcgtc gtcggccggg tagacggtga tgaacttgcc cgccgaacca cgctcactgt
    12661 tacgggagtt gagctcgcgc agccgctcct ccgcagcggc gaacttgaag ctgcacgggt
    12721 ccacggcgag cacccgcagc accgccgcga gcacctcccc gccgaccatc gaggccgcgc
    12781 tgacgtggag cttccagccc tgctccggta agggcgagga cgcggacggc ctggccgtgc
    12841 accagaagcc cccgacggtg acctcccaag caccgccgcc tccccggcct ccggcaccgg
    12901 ccagtgccgc ccgcgccgcc tccggccagc cgccggccgc atcatccggt ccgtgtcccg
    12961 ccgatccccc gcccacagca gtacgcagcg atgtgcccgc ccccattcgc caccacatcc
    13021 cttcgtccgt tgttgtcggg gaacccctcc ggggggatga ggactgggcc gctcgatcga
    13081 cgggcccgga ccgcgtcggc agcgctccca ccccggcttc cggccggggc gaacggggca
    13141 actgccgttc gcaggactga agttagtttc gagaaaaccg cgggctcaac gcagagccgg
    13201 tcacttcact cgtaagggtg agccaggggc ggtttcgaat tcgtacgaga accctgctgt
    13261 gagtaacggt cgccgggcgt gcgggagcgc gccgcccgcg cggggcgctc ggggcgcccc
    13321 cgtcgcaggt tgacgcgcat ccgtacggcc ccggcacccg cgaccgaacg gctccggacg
    13381 cccgcgcggg accgccgacg gcgtcccccg atcggccgag gcccgaccgc ccccgcgcgc
    13441 acggtagtct cgacaggtgc cgaaactgtc cgacgtcatc accgcgctcg aagaggtcta
    13501 ccccccgcag tgggcggagt cctgggacgc cgtcggcctg gtctgcgggg accctcaggc
    13561 cgaggtcagc cgcgtgctgt tcgccgtcga ccccgtccag gcggtcgtcg acgaggccgt
    13621 ggagtggggc gccgacctgg tggtcaccca ccaccccctg tacctgcgcg gcaccaccag
    13681 cgtcgccgcc accaccttca agggccgggt ggtgcacacg ctgatcagca acggcatcgc
    13741 gctgcacgtc gcccacacca acgccgacca cgccgacccc ggcgtctcgg acgccctcgc
    13801 agaggcggtc ggtctgcggg tcaccggccc gctggtgccg gaccccacgg acccgctggg
    13861 ccgtcgcggc tccggccgga tcggcctgct ggagaccccg ctgacgctgt ccgccttcgc
    13921 cgcgcaggtc gccagtggcc tgcccgccac cgccgccggc gtacgcgtct ccggcgaccc
    13981 gaaccggctg gtgagccggg tggcggtgtg cggcggctcg ggcgacggct tcctcgccga
    14041 cgtacgggcg gccggcgtgg acgcctacgt gaccgccgac ctgcgccacc acccggcctc
    14101 cgaggccacc gaggccgcgc cggtcgcgct ggtcgacgcc gcccactggg ccaccgagtg
    14161 gccctggctc ggcctggccg agcgcgccct gctggccgcc gccgaccagc gcggctgggc
    14221 cgtggagacc aaggtctccc accgggtcac cgacccgtgg accgcgcacg cccccatgtc
    14281 cttcaccgcc tgacccgatt cacaggagct ttccgcttga acgccgcgcc cgccgaccag
    14341 atccgcctgc tcgacctcca ggccatcgac tccaagctcg accagctggc ccaccggcgc
    14401 cggagcctgc ccgagcacgc cgagatcgag aaggccaccg ccgaccacac cgcgctcaag
    14461 gacctcgtca tcgccgccga ggcccagaag ggcgacaccg cccgcgagct gaccaaggcc
    14521 gagcaggacg tcgagcaggt ccgtgcccgc gccgcccgca accagcagcg cctcgactcc
    14581 ggcgcgatca cctcgccgaa ggacctggag aacctccagc acgagatcgg ctcgctggcc
    14641 aagcgccagg gcgacctcga ggaggtcgtg ctggagatca tggagcgcca ggagagcgcc
    14701 aacacccggg tcgaggagct gagcgcccgc ctggagcact ccaccgtgat cctcaaggag
    14761 gccgagggcc gccgcgacgc cgccttcgcc gagatcgacg ccgaggccga caaggtcaag
    14821 cgcgaccgcg agaccgtcgc cgccgtcatc ccggccgacc tgctgaagct gtacgccaag
    14881 ctgcgcgaga cccagggcgg cgtcggcgcg gcccgcctct accagcgccg ctgcgagggc
    14941 tgccgcaccg agttctcgat caccgagctg aacgcgatca aggccgagcc ggccgacaag
    15001 gtcgtccgct gcgagaactg ctcgcggatc ctggtccgta cggccgactc gggcgtctga
    15061 cccggtggcg gcgcgcttca tcgtcgaggc ggacggcggg tcccggggca acccggggcc
    15121 ggccggctac ggcgcggtgg tccgggacgg cgacaccggg cagctcgtcg cggaggccgc
    15181 cgagttcatc ggccacgcca ccaacaacgt ggccgagtac cggggcctga tcgccggact
    15241 cagggctgcc cgcgagctcg acccggacgc ctcggtggac gtccggatgg actccaagct
    15301 ggtcgtcgag cagatgtccg ggcgctggaa gatcaagcac cccgacatgc agccgctcgc
    15361 cgccgaggcg cgcgcggtct tcccgcacgg ccgggtcacg tacacctgga tcccgcgcga
    15421 gcggaacaag gacgccgacc ggctggccaa cgaggcgatg gacgccggcc gcgacggccg
    15481 ccagtgggag ccccgcaagc ccgtcggggc cgtcgccgtc accgaggagc cgccgctcga
    15541 gcaggccgtc cccaaggccg gctgggccgc ccccgccgac ctcggcaccc cgaccacctt
    15601 cgtcctgctg cgccacggcg agaccccgct caccccggag aagcgcttct ccggcagcgg
    15661 cggcaccgac ccggagctct ccgacaaggg ccgctggcag gccgagcggg tcgccgaggc
    15721 gctggccgcg cgcggcagca tccaggcggt cgtggcctca ccgatgcggc gcacccggca
    15781 gaccgccgag atcgtcgccg cccggctcgg cctggaggtc cggtacgagg acgggctgcg
    15841 cgaggtcgac ttcggcgcct gggagggcct gaccttcgcg gaggtgcggg agcgctaccc
    15901 ggacgacctg acggcctggc tcggctccgc caaggccaag ccgaccggca gcaccgagag
    15961 cttcaccacc ctcacccacc gggcgggcgt cacccgggac aagatcctcg cccggtaccc
    16021 gggcaagacg gtgctggtgg tctcccacgt cagcccgatc aagacgctgg tccggctcgc
    16081 cctcggcgcc ccgccggact cgatgtaccg gatggagctg tccgccgcct cgatctgcgc
    16141 cgtccagtac tacgcggacg gcaacgcctc gctgcggctg ctcaacgacg cctcgcacct
    16201 gcgttgaagc cccttccagc gggggtcagc gcacgtcgcc ggggtcagtg cacctcggtg
    16261 accaccacgt ccagctgcca cggcttgcgc gccgtgccct ccgcggccag ctcgacgtgg
    16321 tggcccagcg ccagcagcgc gtccatcagc tcggtcgggg tcttcggctc ggtcccggcg
    16381 accagcaggt cccgaacgat ccgccccttg gtcgccttgt tgaagtggct gaccaccgtg
    16441 cgcttgccgt cccgctcctg cagcacccgg acggtcgcgg tacgggaggc cacctcgccg
    16501 gccggcttcc aggccgccgc gtaagcggag ctgcgcaggt ccagcaccag cccgtccgcc
    16561 acctccggga gcacggaggc cgtcgcgctc cgccagtacg cgccgagcgc ccccagtccg
    16621 gggagtttca cgcccatcga gcagcggtag gacgggatcc ggtcggagat ccgcaccgcg
    16681 ccccacagac cggagaacac cagcagcgag cgctcggcgc ggtcgtacgc ggcggcgtcc
    16741 agggtggcca ggcccaggtt gtcgaacagc accccggtgt acacctcggc ggccgggcgg
    16801 gccccggcgg tgggcaggcc tgcgttcttg gcgatctcgc cgcgcaggcc gggcgtgagc
    16861 ccgagtacct cggcggcggt gtcctcgtcg ccccggcaca acccgaccag cgcgtccagc
    16921 accgcgccgc gcgccgccgt cagccccgcc agcgacagcc gctcgagcgc gaccggctcg
    16981 ccgtccccgg acgcggcctt gccctccgag ggcggcaaca gcaccagcac agcggactcc
    17041 tcaacacttt gtggcggacg aaccccgcca ccctactgcg gccgctccgg cgcccaacgc
    17101 cacgcacagg ggcgagtagt accgcacgtt cagccgccgg aaccgctccg tgcgcccgct
    17161 gacccgcccg aacaccaccg gcccggccac cccgcgcgcc accagcaccc cggccaccgc
    17221 ccgcaccccg gcccgccgca acgcccgcgg accggcctgc ggcagcactc cggcctccgc
    17281 ccccaccagg taggaggccg cccccaacaa ccccgccacc gccaggcacg ccccggccgg
    17341 cggcaccccg tcccccgtgc cgaccacggt gtccgcgaag tcctccggcg tccgcaacgg
    17401 ccagggcgtc accgcccaca ccgcgtgcag cgccccggtc accgccaacg ccgccgacac
    17461 cgcacccccg gcgacccgta ccgcagcacc catgcccgaa ccccctccgc cctgttccac
    17521 ccccaccgta cgagtgctca caccgccgcc gacacccgca ccgggccgcc cgacgcacgc
    17581 ggccgccgcc ggggcggcgg caattcggtg ggaatgtccg gcgttcccca ctacggtgag
    17641 ccgcaccacg gtgagccgcg aaggagagtg accgagatga ccatgcgacc cctggacctg
    17701 gtgcccggcg acggcgaagc cgtggaggag tccctgtccg tgcgcctgcc cgccggcctg
    17761 ccggacgaga cccggcaggc cctggagttc gcgctgcggg ctgccgcgca ggcggtgatg
    17821 gccgggcgcg tccgggtgac ggaggcggcc accgggtcgg acaccgccga actggccttc
    17881 gaggtccgcc agtccgagct cccggaggcg ctcaccgagg gcgcaccggg caaggccgag
    17941 cgccgcgccg ccatggtggc ccggatccgc gccgccaacg cggagacgct ggagaggctg
    18001 aaggacctgt gaccaccgag tacctggacc tcgacgacgt cacctacctc gccgggggcc
    18061 cgcagaacgt ccgcgacctc ggcggcctgc tctcggcgat cgcccgcccg caggcgagcc
    18121 tcttcggctc cgacgcctac cccgacctgt ggaccaaggc ggccgcgctc ggccagagcc
    18181 tggcccgcaa ccacccgctg gtcgaccgga acaagcgcac cgccttcgag gcgatgctgc
    18241 tgttcctgga ctacaacgcc gagccctacg ccgacccgca cccggacgac gccgtggcct
    18301 tcatgctgcg gctcgccacc ggcgggtacg acgacgcgat cgggctcgcc gccaaggacc
    18361 tgaagtccct gctcgggcgc tgagggcgcg ctgagcctcc gtccggaatc acctgattcc
    18421 gccctacgct ggcctgcatg cctcgccgaa aactacgcgt caaggccgcc gactccgccc
    18481 ggatcaacac cgagctgacc gaactgcgca cccacttgga gatccacacc gagtggcccg
    18541 aggcggtgct cgccgaggcg gaggaggcgg ccgagcaccc gtggctgccg gagcacgacg
    18601 ccaccgacct gccgctgttc accgtcgacc cgcccggctc ccgcgacctc gaccaggcca
    18661 tgcacctcag ccaccgcccc ggcggcggct accgggtgca ctacgcgatc gccgacgtcg
    18721 ccgccttcgt ccgccccggc ggcgccatcg acgccgaggc ccgccgccgg gtcgagaccc
    18781 tctacttccc cgaccaccgc gtccccctcc accccacccg gatctccgag gacgccgcca
    18841 gcctgctgcc cggcgagccc cgcccggccc tgctctggca gctggacctg gacgccgacg
    18901 gcgccgtcgt gctggcggac gtccgccgcg ccctggtgcg ctcgcaccgc cgcctggact
    18961 acgccgccgt ccagcgcgcc gtggacctcg gcggcgccga cgagcagctc gccctgctcg
    19021 ccaccgtcgg ccgactgcgc gaggagcagg agcgcgcccg gggcgggatc agcctgccgg
    19081 tgcccgagca ggaggtcgag gagaccctgc acggctacgt cctcggctac cgcgcgccca
    19141 gccccgccga cggctggaac gcccagatct cgctgctcac cggcatggcc gcggccgaac
    19201 tgatgctgga cgcgggcgtc ggcctgctgc gcaccctccc cgccgcgccc gccgccgcgt
    19261 acgagcggct gcgccggatc gccgccgcgc tggacgtcga ctggccgcag gccgtcccgt
    19321 acccggagct gatccgctcg ctggacccgg aggtgccgct caacgccgcc ttcctcaacg
    19381 cctgcaccgg tctgctgcgc ggcgccggct accacgcctt cgacgagtcc cgcggcctgc
    19441 ccgcccccgc cgagccgggg cacgccgcgc tggccgcccc gtacgcgcac tgcaccgcgc
    19501 cgctgcgccg gctcggcgac cgcttcgccc aggaggtgtg cgtggcggtg gcggcggggg
    19561 aggacgtgcc ggactgggcg cgggaggcgc tgccggccgt gccggcgctg atggcgggcg
    19621 gggaccggcg ggcgggcgag gtcgaacggg cctgcgtgga cctggtggag gcggagttgc
    19681 tggtcggccg ggagggcgag gacttcgccg cggtggtcat cgaggtggac gagaggcgtc
    19741 ccggctcggg caccgtccag ctgcgcgagc cagccgtccg ggcccgctgc gacggcgcgg
    19801 cgtccggctc gccggacggg gtcgccgccc ggctgccgct cggccggatg atcgacgtcc
    19861 ggctcaccac ggccgacccg gcgacccgga cggtccgctt cgccgcggtc tgaggcgccg
    19921 tccgatggtc caccgccgga agcccgaagc cggacgccgg aagccggaaa accggagacc
    19981 gaagccggag accggaagcc ggagaccgag agccgccgac ccggccaccc ggacggtccg
    20041 ccgtaccacc ccgcccccgc cccggagtgg gaggatcggt ccgtgcccga tccccagccc
    20101 cccgccgcca tccccgccgc ccgcgtcccc gtcgccgggc ggcgccgccg tctgctcgtc
    20161 ctcgcgatct gctgcctgag cctgttcatc gtcggcctgg acaacaccgt ggtgaacatc
    20221 gcactgccgg tgatccagaa ggacctgggg gccccggcct ccggcctgca gtggatcatc
    20281 gacgcctaca ccctggtgct ggcctcgctg ctgatgctgt tcggctcggt ggccgaccgc
    20341 ttcggccgtc gccgggtgtt ccagatcggg ctgacctgct tcgcgctcgg ctcgctgctg
    20401 tgcagcctgg cgccgagcct ggagtggctg gtggtgttcc gggcgctgca ggcggtgggc
    20461 ggctcgatgc tcaacccggt ggcgatgtcg atcatcacca acaccttcac cgacccgaag
    20521 gaacgggccc gggcgatcgg cgtctggggc ggtgtggtcg gcatctcgat ggcgctcggc
    20581 ccgctgctcg gcggcttcct ggtggacggc gccggctggc cctcgatctt cctgatcaac
    20641 gttccggtgg ccctgctcgc catactgctg accatccgtt acgtccccga gtcgcgcgcg
    20701 ccgcggccgc gccggctcga cccggtggga cagctgctga tgatcgtgct gctcggctgc
    20761 ggcaccgccg cgatcatcga gggcccgggc aacggctgga cctccccgct gatcctcgcc
    20821 ctcgccgcgg ccgcggtggc cgcgctgatc gccttcccgc tctgggagcg acgggtcgcc
    20881 gagccgctgg tggacccgcg gttcttcgcc agtgcgccgt tcaccggcgc caccgtcacc
    20941 gcggtctgcg ccttcgccgc gctcggcggc ttcctcttcc tcaacaccct ctacctgcag
    21001 gacgtccggc actacggccc ggtcgaggcg ggcctgtgga cgctgccgat ggccgggctg
    21061 atgctggtct gcgcgccgct gtccggacgg atcgtcggca gccggggccc gcgcctgccg
    21121 ctggtggtgg ccgggctcgg cctggccgcg agcgacctgc tgctcacccg gctgaccgcg
    21181 gactccccgg ccgcgctgct gctggtcgcg tacgcgctgt tcggtttcgg cttcggcatg
    21241 gtcaacgcgc cgatcaccaa cgcggccgtc tccggcatgc cgcgctccca ggcgggcgtg
    21301 gccgccgccg tcgcctcgac cagccgccag gtcggccagt cgctgggtgt cgcggtgatc
    21361 ggtacggtcg tcacctcggc cgtggtcggc ccgctggcca ccggcttcgc cccggccagc
    21421 cacgccggct ggtggatcct ggtcggcctc ggcgccgcga tcctcgccct cggcgtgctc
    21481 accaccggca cctgggccac cgacaccgcc gcccgggtgg ccgcccgcct cggcgccgag
    21541 cccccggtgg cccggtccgg tgttcgggag gccccgcccg agcggctacc atgaccacta
    21601 cggcggaaga gccggccggg cggtcgcgac gggtccctga cccgccgagg aacgtccggg
    21661 ctccacagag cagggtggtg ggtaacgccc acccggggtg acccgcggga cagtgccaca
    21721 gaaaacagac cgcccaccgc ttcggcgcgt gggtaagggt gaaacggtgg tgtaagagac
    21781 caccagcgac cggggtgacc cggccggcta ggtaaacccc acctggagca aggtcaagat
    21841 cggtgcctcc gggcaccgtg cgcgagtgtt cgagggctgc tcgcccgagc tcgcgggtag
    21901 accgcacgag gctgtcggca acggcagccc tagatggatg gccgtctccc cgggccgcgc
    21961 aagcgacccg ggtgacagaa cccggcgtac aggccgactc ttccgtcgcc gatctgaggg
    22021 aaggcccctg acctgcgaaa cagcaggtca gggggccttt tcatgcctcg aagacctgta
    22081 accacttgct gactcttcgt ttctgtttct gcctgtttct gggtgtgctg tggcgatcgc
    22141 gtggcggtga gaactgtcga aacagccatc cgagacccat gcgctgatca cgacagcact
    22201 cgacgcgcga ctcagctggc cagcgcctcc ccgagcagcg cgtacggccg accggtgagc
    22261 tggcgatgca gcgtctcggc gcgggatcgg atcagaccct cacggtaggt ggccggcagc
    22321 cgctcccaca ccccggatgc catttcggcg gcaccggacg ggtcgccgtc gacgtgcagg
    22381 catgcggcgg tgtccactgc cagcagggcg cgcaccatca ccgacggaga atccgtgagc
    22441 gccagggcgt cctcctgcgc ctggtgggcg ctgcccgtgt cgcccagcag tgtgtacgcc
    22501 tgcgacaggt gcacgtggtg cttctgctcg gggtagccaa accaggtgtc ggccgcctcg
    22561 gcgccgtcca ggcgctccgc gagattgcgc gcgtcgtcca gtgctcgccg ggccccatcg
    22621 aggtctccgg aggtcgcctg cgctggagaa cctgctggag atgttccgcg agtgcccgcc
    22681 ctaccgagtc acggtgtcga tgtacggggc gaccaaggcc agctacgacg agctgaccca
    22741 gcgacagggc gcctgggacc tgttcatcca gggcatgaac gccgcccgcc gcgccaggct
    22801 cccactgcgg atgagcatca tcgtcaccga ggacaacgcc accgaggaac aggcgatgat
    22861 cgacctgtgt gaaggctggg ggctggagta caacgtcttc gccaacttga ctccgacgat
    22921 ctacggcggg gcggagtcgc tgaccacgca gtccaaggag cacctgcgaa tgcgcaagcc
    22981 gttcggaggc tgcaacgccg gacacacctt cttccaca
//
