LOCUS       NZ_CP115450            23831 bp    DNA     linear   CON 17-DEC-2024
DEFINITION  Kitasatospora cathayae strain HUAS 3-15 chromosome, complete genome.
ACCESSION   NZ_CP115450
VERSION     NZ_CP115450.1
KEYWORDS    RefSeq.
SOURCE      Kitasatospora cathayae
  ORGANISM  Kitasatospora cathayae
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Kitasatospora.
REFERENCE   1  (bases 1 to 8860963)
  AUTHORS   Zheng,Y., Mo,P., Li,J., Zhou,Z., Huang,K., Luo,Y., Xie,P. and
            Wang,Y.
  TITLE     Kitasatospora cathayae sp. nov., a novel endophytic actinomycete
            isolated from the leaves of Cathaya argyrophylla
  JOURNAL   Int J Syst Evol Microbiol 74 (5) (2024)
   PUBMED   38809239
REFERENCE   2  (bases 1 to 8860963)
  AUTHORS   Mo,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-DEC-2022) College of Life and Environment Science,
            Hunan University of Arts and Science, No. 3150 Dongting Avenue,
            Changde, Hunan 415000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 8.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 155.15x
            Sequencing Technology             :: Oxford Nanopore PromethION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_027627435.1-RS_2024_12_16
            Annotation Date                   :: 12/16/2024 15:42:53
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,288
            CDSs (total)                      :: 8,175
            Genes (coding)                    :: 7,919
            CDSs (with protein)               :: 7,919
            Genes (RNA)                       :: 113
            rRNAs                             :: 11, 11, 11 (5S, 16S, 23S)
            complete rRNAs                    :: 11, 11, 11 (5S, 16S, 23S)
            tRNAs                             :: 77
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 256
            CDSs (without protein)            :: 256
            Pseudo Genes (ambiguous residues) :: 0 of 256
            Pseudo Genes (frameshifted)       :: 79 of 256
            Pseudo Genes (incomplete)         :: 220 of 256
            Pseudo Genes (internal stop)      :: 9 of 256
            Pseudo Genes (multiple problems)  :: 51 of 256
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:37:27
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4145024
            Orig. end                         :: 4168855
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP115450.1.
            Bacteria and source DNA available from Mo Ping.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23831
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="16"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..23831
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23831
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13831](+)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13831
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            complement(111..1760)
                     /locus_tag="O1G21_RS18325"
                     /old_locus_tag="O1G21_18325"
     CDS             complement(111..1760)
                     /GO_process="GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014628173.1"
                     /locus_tag="O1G21_RS18325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_18325"
                     /product="LCP family protein"
                     /protein_id="WP_270145185.1"
                     /transl_table=11
                     /translation="MPPPRSGGRAEARRAAQGKGGGKADGGPGGRAAARRSAKPKKNVK
                     KIVAWSAAGVLVLIAGTGGAIYYKLNANIKSFDADAIAPDRPPEAKADADGNKPVNVLL
                     IGSDSRGGNNSDLGGGEDGGARSDTTILLHVYADHKHAVGISIPRNAIVPIPSCKLPNG
                     KWTKGGNDLFNAAFSVGGSDSGNPACTQNTVEKVTGIRVDHTMVVDFNGFAAMTKAVNG
                     VDVCLPKPIYEGDINPNLHKKGNLVLPQGKQTVEGQQALDYVRLRHGIGDGSDIGRMKR
                     QQAFMSSLATKMKKEGLSPTNLLPLADAATKSLTVDPGLDSADKLLSFGLSLKNIDMHD
                     LKFVTAPWRYRTQDANIDLVQPDANKLWETLKADQTIDGQNATGQQPDAGGSPSAAPQQ
                     AAPSTPPAPAGDASNAAIKVAVYNGTLANGLAGKATDLLKGAKFTASTAGQAASTKYKT
                     TTIEYSSSQKANAEKVAALFPGATLEPSSSRGISVIVGQDFAAANGMGAPTAAGSTPGT
                     QTPPQPLPTTVTNDARSADDDICANTTYGSGG"
     misc_feature    1956..1970
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.56"
                     /tool="antismash"
     misc_feature    complement(1967..1981)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.06"
                     /tool="antismash"
     gene            complement(2092..3771)
                     /locus_tag="O1G21_RS18330"
                     /old_locus_tag="O1G21_18330"
     CDS             complement(2092..3771)
                     /GO_process="GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014146349.1"
                     /locus_tag="O1G21_RS18330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_18330"
                     /product="LCP family protein"
                     /protein_id="WP_270145187.1"
                     /transl_table=11
                     /translation="MAENTEQPPHAEQPPRGGRAAARKASGGGRSPLLIAGRVVACTVG
                     FTVFAASGVVWYEYTSLTDGMTTSSVIEQTKKDAPKHLDNSVNLLLIGLDSRKNMDGSD
                     VDPAIVQNELHAGADSSIGGYNTNSLILLHIPAGGGKVQGISIPRDDYVMTYDGDGKEM
                     GMAKIKEAYGNAKEAFNNSPKAKGLKGADLEKAGRDVGRAATIRTVQKFVDQPVDHIAE
                     VNLMGFYDIAKVLQPIEVCLTHPVDDPIIARTTTHEGGGTGLKLPAGRSKLDAAQALSF
                     VRQRHHLNDGHGDSDDFARTHRQQAFISGVMHKLKEQGVVGDLGAMQKMFGVIQQDLVI
                     DNEWNVLDFAQQAPALTGGNVEFNTLTFDREDMKGGEAVNIVTPSKIQKVVKQVFGGAD
                     AAAPAPAPADTPSGDPTATQAPTQTATPTQAAAPATVDVFNASSAAGVSSSNEAKVLVG
                     LGFKQGVTGPARTKPKATTVTYGKGAKEAADQIAARYGVTATESSSAGAGHVVVTLGTS
                     FDGVASDRPAAPSTAPDDPAANVAMQGPKVEAQSDGGIPCVF"
     gene            complement(3927..4925)
                     /locus_tag="O1G21_RS18335"
                     /old_locus_tag="O1G21_18335"
     CDS             complement(3927..4925)
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017944321.1"
                     /locus_tag="O1G21_RS18335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_18335"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_270145189.1"
                     /transl_table=11
                     /translation="MTREIDDAAQAVYRLMLTDHQLDVEGLAGKLGLTEEQVRAALDQL
                     AGLRLLRPFEPSGDEAPGEPSGGLRPVDPRVGLPALLRYYESVQQRAQLEFEQRQAEIS
                     GMLAQFRDESAPEDSQLERLLGTATVHARMEELVGSVREELLTFAPGRARSVASLQASR
                     PDNEKLLARGVTMRTVYLDVVRKDRATVQHAEWLTGLGCEIRTVPALPLRMLVIDRQVA
                     LVPIDPANTLKGAVQISSPGVLAALVSLFEQIWSDATPFGAPCERDEEGLTRQEQELLR
                     LLGQGYTDEAAGKHLGVSLRTTRRMMADLMDRLGARSRFEAGLLAGRRGWL"
     misc_feature    5007..5022
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.25"
                     /tool="antismash"
     gene            5296..5508
                     /locus_tag="O1G21_RS18340"
                     /old_locus_tag="O1G21_18340"
     CDS             5296..5508
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O1G21_RS18340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O1G21_18340"
                     /product="hypothetical protein"
                     /protein_id="WP_270145191.1"
                     /transl_table=11
                     /translation="MLISCRTFACTAAAALAVAGGVLAGSAHAAPAAGPTTASVQQFTN
                     HLPTQPRQPQLPTLGGAATPGDWHW"
     gene            5656..6546
                     /locus_tag="O1G21_RS18345"
                     /old_locus_tag="O1G21_18345"
     CDS             5656..6546
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O1G21_RS18345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O1G21_18345"
                     /product="hypothetical protein"
                     /protein_id="WP_270145193.1"
                     /transl_table=11
                     /translation="MPVIEPIVLNFFGLEIALVQADRDEISFHFGPHLTGISRDPDQLW
                     VEFSRTPGKDAPGDFLVRRSDGTPLLRRTFRGWGNVPSAVPPFAALQDRFCLAQAVVLA
                     KGGATVALVGGPYSEQANVGAALAQRSWEFVSGRLLVLDRRTGHVLPYLAPLEARGPAA
                     AWLRGAGLPDGMWRTVTSPVGGEVLLVRPESLGPVVPVRARLAPPSLVRLCRSIDEEVR
                     LAPWEFTTHTWPAGSSGALAGAPTHCLHLPGVSGAEEAAGLIDQAMTKEKDEPCLDVPA
                     MPSALRAGLTASLPI"
     gene            6480..7187
                     /locus_tag="O1G21_RS18350"
                     /old_locus_tag="O1G21_18350"
     CDS             6480..7187
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037170.5"
                     /locus_tag="O1G21_RS18350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_18350"
                     /product="VOC family protein"
                     /protein_id="WP_270145195.1"
                     /transl_table=11
                     /translation="MPRRTSYAIGAPCWADCITPDLSGSREFYSALLGWEFVTESPDYQ
                     LVVLGGEIIGGFGAAPVGLPPQAAWNVYLATKDAEHCCVQVGRLGGRVVMPPVPAGENG
                     RLLLAVDSSGVTVGFWEGARAEGVVLADEPGAICGHELRVPSAIQAEAFYGPLFGYRLG
                     ADGQFAVDGFGYARVVESDQGRPCWLPLFGAADPADAVRRAVGLGARLVRPGAEEPPVL
                     RDPWGAEFGLVPA"
     gene            complement(7200..9773)
                     /locus_tag="O1G21_RS18355"
                     /old_locus_tag="O1G21_18355"
     CDS             complement(7200..9773)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024589.5"
                     /locus_tag="O1G21_RS18355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_18355"
                     /product="AAA family ATPase"
                     /protein_id="WP_270145197.1"
                     /transl_table=11
                     /translation="MPTGVLLHRETELAELARAVAGAGAGRSAVVLVRGPRGIGKSALL
                     RAALARMPGEAVVLRARCHDNERDFPYGVVRQLFDPFMRMTNNPEATPQFLGESPGEFL
                     AEALPEALPGGAPTAHPAGPESVGNGRERVLNNLFHAARSLTSRTPVVMAVDDLHLADE
                     ESRQWFSYLARRLDGLPVALLASTADEAADPLAAELAALRHARTLTPGPLCDSCVADLV
                     AEEFDAPVDPELAAVCHNLSRGNPLVVEELTARLAAARISPGSPDLDKVLRIGAGTLAD
                     TTLSWLRQSHPRAAELLTGLAVLGADADLATAALLTGQGELLADEAREALRRTDLIEPG
                     PPETFRHELVRTAVLARTDPRVLVALHERAAALLARLGAPAARTAEHLMSSGTTGLDWA
                     VPVLRTAAREAAADGHWDDAARYLQRALADAADPELVRSLTGQLGTVELHRDVAAAARC
                     AAGLAAGAPDPVERARLLRPFAGPVLALSAAGAAAVPSAEAAAALAGTPAPPAELLLPL
                     AAQAVLTGRRTALRPALAALRAHPAEPAATGMLGALAALAAAGGQPRTAVRLAARCVRR
                     VSPAEAGTDVLGAAMAYAWTGRLDEAAAWAGRVVRSAQRWNHRGELALALLARSDIAHR
                     QGRLDAALADAEQAAELARRIRAEDLAGAARALAVRARLRRGLPVDAATADAEPAAVEL
                     PAEAHPLLRAVVLEARGLVAAHRGDHQQALRLFLECGHQLAARGVANPACVPWRSHAAQ
                     AYQALGEHAAARTIAADPLPGGDARPRPAEERGGPAIGTRDAGPVRLTPSERRVTELVL
                     QGLSNLEVAERLCLSKRTVDTHLGRIYRKLAIKGRPELGAAVKAL"
     misc_feature    9789..9806
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.94"
                     /tool="antismash"
     gene            10001..12277
                     /locus_tag="O1G21_RS18360"
                     /old_locus_tag="O1G21_18360"
     CDS             10001..12277
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03882"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NHLP_CD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cyanobactin_D_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Goadsporin_CD_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03604.1"
                     /locus_tag="O1G21_RS18360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_18360"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_270145199.1"
                     /sec_met_domain="NHLP_CD_RRE (E-value: 5e-14, bitscore:
                     50.9, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="Cyanobactin_D_RRE (E-value: 2.4e-10,
                     bitscore: 39.1, seeds: 10, tool: rule-based-clusters)"
                     /sec_met_domain="Goadsporin_CD_RRE (E-value: 2.4e-08,
                     bitscore: 32.8, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03882 (E-value: 6.3e-45, bitscore:
                     152.1, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 6.1e-91, bitscore: 304.4,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 3.3e-73, bitscore:
                     245.5, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERPRLKAHFLTETVGEKVFLLGEGQDYLVPGAAAVRLLPYLDGR
                     RTVAEILQELGGEIGLGQALTALRRYEAAGHLAEGRPDLPDHVLAYWDAQGVDPAVALA
                     AARATELLVLALGAAEATPLVEALTATGLRARAVTEDQAVAAGPDTLVVALTDDYLDRA
                     LERLNTARLADGRPWLLAKPTGTSPWLGPLLRPGETGCWSCLAQRISGNRQVERYLAGK
                     RGETVPLHPTRAAIPAGPAMTAQLLATEAARILADECCSALSGTMVSLDLNTLQTTEHT
                     LVRQPQCPSCGDPALLTERSPKVVLQPSPARHTTDGGYRVQAPQFTYDRLKHHISPHLG
                     AITRLGAHEDTGNGITYSFTAGHNFAMVNDNMDLLRRNMRGQSGGKGRSEIQAKVSAIC
                     EAIERYSAVWRGEEPVVRAAYRDLDPAVAVHMDALLQFSDAQFANRAEWNADPKHRLHL
                     VPDPFPVDAELDWTRAWSLTHDEERLVPSGYAWYGHPDLQQHFYCVGDSNGCASGNTLE
                     EAILQGFCEVVERDAVALWWYNRTAQPEFDLDSLNDPYVDTMRAFYASVDRELWVLDIT
                     SDLGVPVFAAISRRKHEVEDIMVGFGAHPDPKIAAIRALTEVNQFLPFVDRRDENGNTL
                     YRTDDLETLEWCRTATIAGEPWLLPDRAQPASTLADFAPLTGDDLAGHVRDCVERARRA
                     GVEVIVLDQSRPDLDLAVVKVIAPGMRHFWRRLAPGRLYDVPVRQGRLAAAHTEEQLNP
                     KNVFF"
     aSDomain        10004..10279
                     /aSDomain="NHLP_CD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing CD fusion protein in a
                     NHLP/Nif11 LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_O1G21_RS18360_NHLP_CD_RRE.1"
                     /evalue="1.80E-16"
                     /identifier="RREFam015.1"
                     /label="O1G21_RS18360"
                     /locus_tag="O1G21_RS18360"
                     /protein_end="93"
                     /protein_start="1"
                     /score="50.9"
                     /tool="antismash"
                     /translation="ERPRLKAHFLTETVGEKVFLLGEGQDYLVPGAAAVRLLPYLDGRR
                     TVAEILQELGGEIGLGQALTALRRYEAAGHLAEGRPDLPDHVLAYWD"
     aSDomain        10013..10231
                     /aSDomain="Cyanobactin_D_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing D protein in a cyanobactin
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_O1G21_RS18360_Cyanobactin_D_RRE.1"
                     /evalue="8.60E-13"
                     /identifier="RREFam007.1"
                     /label="O1G21_RS18360"
                     /locus_tag="O1G21_RS18360"
                     /protein_end="77"
                     /protein_start="4"
                     /score="39.1"
                     /tool="antismash"
                     /translation="RLKAHFLTETVGEKVFLLGEGQDYLVPGAAAVRLLPYLDGRRTVA
                     EILQELGGEIGLGQALTALRRYEAAGHL"
     aSDomain        10016..10291
                     /aSDomain="Goadsporin_CD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing CD fusion protein in a
                     goadsporin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_O1G21_RS18360_Goadsporin_CD_RRE.1"
                     /evalue="8.50E-11"
                     /identifier="RREFam013.1"
                     /label="O1G21_RS18360"
                     /locus_tag="O1G21_RS18360"
                     /protein_end="97"
                     /protein_start="5"
                     /score="32.8"
                     /tool="antismash"
                     /translation="LKAHFLTETVGEKVFLLGEGQDYLVPGAAAVRLLPYLDGRRTVAE
                     ILQELGGEIGLGQALTALRRYEAAGHLAEGRPDLPDHVLAYWDAQGV"
     misc_feature    10049..10060
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.03"
                     /tool="antismash"
     gene            12299..13831
                     /locus_tag="O1G21_RS18365"
                     /old_locus_tag="O1G21_18365"
     CDS             12299..13831
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF013077.5"
                     /locus_tag="O1G21_RS18365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_18365"
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_270145201.1"
                     /sec_met_domain="PF00881 (E-value: 1.3e-13, bitscore: 50.2,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTATTPATATALDGIDLPATARTVRRLRLRPDGALTPLGPKAVR
                     LTAPVGALNLPDLAPGAMEAVAALAAGEQTEEELAALVAARDGDAGLLRWQLTRRRLGT
                     AGMLEHSVHLVLDGADEPLARLRPVGRGAAEPGPTPDPTGQVKLSRFASASVEGGALLV
                     RAPGSPLAVQLTTRAAGLLAALAGWTSPAALAQLPDGLPLDAVRQTLRLFAAAGLLAYG
                     SPGAEPEAEEQRFAQWTAADLAFHSRTRRPTSVAGYGGTYRFGDRFAPEPASPAPFAGR
                     KVALPVPDLDELARADRPFTEVLEQRRSVRDHDEQTPITLEQLGELLYRSARRRQTFTG
                     GDGQELADRPYPSGGAVHELELYPLVTSCAGLEPGLWHYATDRHELELVSEPSAATAQL
                     VKSARESSLMQTDPQVVLLVTARFGRVMWKYETVAYPLILKHVGALYQTLYLVGTAMDL
                     AVCGLGGGDAADFAAASGLDYFTEGSVGELVIGSRPPTLRQDVGVPRREARR"
     gene            13828..14640
                     /locus_tag="O1G21_RS18370"
                     /old_locus_tag="O1G21_18370"
     CDS             13828..14640
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024829.5"
                     /locus_tag="O1G21_RS18370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_18370"
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="WP_270145204.1"
                     /transl_table=11
                     /translation="MKFRFKALQRMREPDELDSPTLLAAPRGWIALFVVMITMATALLW
                     TFTGKIPITVDAPGLLTHPHGTAMIQSPFGGMVRTVLAKPADQVRQGQSVVRVEDTEGH
                     SREITSPFGGRVVGLSVTDGQVVAPGSPVASVERVDDPKERLVAMVFVPATRTVGLGPG
                     DQVDLNVSTSPAGAFGLLRGTVSSVSPYALTKEAVSGLVGGDLAAQRYLGKDAPRLVVV
                     DLTPDPDTPSGFAWTSQSGPPNPLGTQVAVTATINVGRQTPFNLILGR"
     gene            14653..16920
                     /locus_tag="O1G21_RS18375"
                     /old_locus_tag="O1G21_18375"
     CDS             14653..16920
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015037648.1"
                     /locus_tag="O1G21_RS18375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_18375"
                     /product="NHLP family bacteriocin export ABC transporter
                     peptidase/permease/ATPase subunit"
                     /protein_id="WP_270145206.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 9.4e-34, bitscore:
                     114.9, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATIPETTPASAPAPEKKPRRGRPTRAAAPRRWRHAVPTVLQME
                     SVECGAASLAMILAHHGRWVPLEDLRGVCGVSRDGARASTLLEAARTYGLKARGYQTEA
                     ENLRDLDGPVIIFWAFQHFMVVEGVRTRYGRTVVAVNDPASGPRLMEWDEFDSGFTGIV
                     LSFEKGPDFEPGGDKGGIGRALLERRLPTGRAMPLVLLASLLLVLPGIAIPAYTRVFID
                     RVLAGSGSGYLLPLLAAMTATAVVVFVLTSVQRHYLLRIEIRMGLVSSARFFRHLLRLP
                     VDFFLQRRPAEVAKRVSGNDVVAEILSRDLALTVINLGLVLFYAAVLIRYDLLLGVVGV
                     GMALLNVVVLQAVARARTDAVAALRTDRGNLTATTFTTLSLIETVKATGAEQDAFGRWA
                     GFLAKVVTAKQKLGIPSAVLTVVPPMLAALNSGLILLVGGQRVVDGAMSVGILVSFQTL
                     LAALSRPVTQLTNLGGRLQDVTADIKRLYDVERYPVAAAFARPEPPAGPKLDGTLEFED
                     VRFGYSPLSEPIIKDLSLTVVPGRRVAVVGGSGSGKSTLGRLLTGLYTPWSGRILLDGR
                     PREEISRTVLASSLAYVDQDISLFEGTVRDNLTLWNDDVPDEAVTAALRDAAVFDTVMT
                     RPGGIHSPVLEGGRNFSGGQRQRLELARALASEPTLLVLDEATSALDPETERVIMDNLR
                     RRGCACLIIAHRLSTVRDADEIIVLQEGSIVERGTHDELLALGGHYTALIESARREEED
                     EL"
     gene            17021..19924
                     /locus_tag="O1G21_RS18380"
                     /old_locus_tag="O1G21_18380"
     CDS             17021..19924
                     /GO_function="GO:0015440 - ABC-type peptide transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0043213 - bacteriocin transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:TIGR03797.1"
                     /locus_tag="O1G21_RS18380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_18380"
                     /product="NHLP bacteriocin export ABC transporter
                     permease/ATPase subunit"
                     /protein_id="WP_270145207.1"
                     /transl_table=11
                     /translation="MSTAVEVFSPILTEAAEPSGERYLVLDDPGRLLLVRSGAVDLFAV
                     QLDSGAPQGRWHFLCRIEAGTLVPGTAAAGARRGIVARPVLGAELSFLATSRVEGLLGA
                     ASGGTSGAADQFLTGLARGLTALAGALRDTLPPREFTPLDPVEPTVLKRGQALRSVDGL
                     QWVRVEQGSVEVPEGSDGELTEGAEVLLTERDWLVATGPATVRARSPRELLDQGGLWER
                     LAAHCGRLLDAVDRRIEARRTAETELIATRRERDAGTLADSARGFETILRDTASRLRIG
                     DATGDEPTLAAARLVAAHEGFTVTAPVAGIGHDRRLDRLQAIALASHVRTRSVRLDGKW
                     WQNDLGAMVGYRKAGAPVALLPLGNGYVLAEGGKVTPLTPKLAAELQNKATVLYRPLPA
                     AVRTVAGLLRFGLRNNRQDLWMFTGMAALVALIGLLVPVMTGEVLGTFVAHAQRNLITE
                     GALVVIGSAMAVAALSIVQNIAVLRIESRSTAAMQVGVWTRLLSLPAPFFADYSTGELG
                     TTVLGVSAAQETLSGMMTTATLGLLTGLANLVLVYFYDLRLAALATLLVLVGVGVGLAA
                     GRLEVRWQRRLYAHEQAMSARVFQLLTAVPKLRVTAAEDRVFGVWAAELGKGRGLAASS
                     RRVQNAVTTFNAGFPLVCSVVIFGVIAGPLDGDVPIPVFLSFFTAFNLLIASSLQFTSA
                     AVTAMGVVPMLERLRPILEEKPEVDDTKADPGDLSGRLGLSHVTFRYGEDGPAALQDVT
                     LSIEPGEFVAIVGPSGSGKSTVLRLLLGFERPESGTVLYDGQDLGELEVSAVRRQCGVV
                     LQHGALLAGDIKANIVGSTNHTLDDAWAAAEMAGIDKDIAAMPMGMNTVLSEGTSTLSG
                     GQRQRLMIARALVSRPRIVFFDEATSALDNPTQRLVTESTRRLNATRVVIAHRLSTVAE
                     ADRIIVMDQGRVVQQGRYEELLADRDGLFARLAHRQM"
     gene            19949..20302
                     /locus_tag="O1G21_RS18385"
                     /old_locus_tag="O1G21_18385"
     CDS             19949..20302
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015735.5"
                     /locus_tag="O1G21_RS18385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_18385"
                     /product="YciI family protein"
                     /protein_id="WP_270145209.1"
                     /transl_table=11
                     /translation="MEYTLLIHGDERVWNGLSEAEQAELDAAHVRFGRALHEAGVTVRY
                     GGGLRRSCSARLVVPGGGAGTPVSDGPYREGHEHLGGLWVIDVADEAEAVSWARWMPAA
                     PGDLVEVRPVRVI"
     misc_feature    20423..20436
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.31"
                     /tool="antismash"
     gene            20544..21263
                     /locus_tag="O1G21_RS18390"
                     /old_locus_tag="O1G21_18390"
     CDS             20544..21263
                     /GO_function="GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009085921.1"
                     /locus_tag="O1G21_RS18390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_18390"
                     /product="G1 family glutamic endopeptidase"
                     /protein_id="WP_270145211.1"
                     /transl_table=11
                     /translation="MRRFLIRVATLAAAATTLAAPAAPTTAAAAQGLSFRPLQYNTNGY
                     NWGGYAATGSGFTSVSASWTEPDATCNSTNDLYAPWVGIDGYGSSSVEQTGVATDCSSG
                     SPVNQAWYEMYPSSPVYLSLSSYPVSAGDHISASVTYIGSSRYTLKLTDSTRGWTYSTT
                     KSISAQRTSAEVIIESPTGSYPNFGTLTFTSATVNGRSLGSYNPVALDPSSNGVYEAST
                     SALGSNGTSFTDTFLAE"
     gene            21569..21700
                     /locus_tag="O1G21_RS18395"
                     /old_locus_tag="O1G21_18395"
     CDS             21569..21700
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O1G21_RS18395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O1G21_18395"
                     /product="transposase"
                     /protein_id="WP_270145213.1"
                     /transl_table=11
                     /translation="MPSTLLERADEPSARACPVCGSGATYQTMDGRWGCTACGSTWA"
     gene            21717..21917
                     /locus_tag="O1G21_RS18400"
                     /old_locus_tag="O1G21_18400"
     CDS             21717..21917
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O1G21_RS18400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O1G21_18400"
                     /product="hypothetical protein"
                     /protein_id="WP_270145215.1"
                     /transl_table=11
                     /translation="MAACTQCSAPAAIEDLDVQPPQPWCLGCATTLVRAGDPVLNYRSL
                     NGESEYQRVLTGGSTQVLPFG"
     gene            complement(21982..23178)
                     /locus_tag="O1G21_RS18405"
                     /old_locus_tag="O1G21_18405"
     CDS             complement(21982..23178)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018092778.1"
                     /locus_tag="O1G21_RS18405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_18405"
                     /product="MFS transporter"
                     /protein_id="WP_405000667.1"
                     /transl_table=11
                     /translation="MPSTSLPASPAAARTSTRGLLRGWLAVASVMTGIFSVVTTEILPI
                     GLLTPIGATFRISDGTAGLMMTLPGIIAAVAAPVVTVAVRRADRRGVLCGLMLALALAD
                     LVNALAPGYWAVLAARVVLGVVIGAFWSIGAGLAPRLVAAERQARANTVIFSAVPLGSV
                     LGVPAGVLLGHLAGWRAAFAAMAVLSLAVSAALAATLPPLPPEAPTRLAVLRGLLRTRA
                     VRAGLAITLLLVTAHFGTYTYVTPFLEDVTHAGPDAVTALLLVYGIAGVAGNFVGGLWA
                     GRRATFTIAISLLAAAVLLLPVLGTAWPGAALLLVAWGLAYGAVPVCAQAWFVRAAPDT
                     PEAATVIFTSSFQATISLGALAGGAVVDTSSPSVVMLLGGCVALLAAAVTHAAALRDQ"
     misc_feature    complement(23104..23106)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    23796..23811
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.54"
                     /tool="antismash"
ORIGIN
        1 ccgggggacc cggcaaggga cccgagcgac aggccctacc gccacgatgg cacgaccccg
       61 gggctcgtgc gccccggggt cgtcccgccg ccgttctccg gtgcccgcgg tcagccgccg
      121 ctgccgtagg tggtgttcgc gcagatgtcg tcgtccgccg agcgggcgtc gttggtgacg
      181 gtggtgggca gcggctgcgg gggcgtctgg gtgcccgggg tgctgccggc ggccgtgggc
      241 gcgcccatgc cgttggccgc ggcgaagtcc tggccgacga tcaccgagat gccccgcgag
      301 ctgctgggtt ccagggtggc gccggggaac agcgcggcga ccttctcggc gttcgccttc
      361 tggctggagc tgtactcgat cgtggtggtc ttgtacttgg tgctcgccgc ctggcccgcc
      421 gtgctggccg tgaacttggc gcccttcagc aggtcggtcg ccttgccggc caggccgttg
      481 gcgagcgtgc cgttgtagac cgcgaccttg atcgcggcgt tggaggcgtc cccggccggg
      541 gcggggggcg tgctgggcgc ggcctgctgc ggggcggcgc tcgggctgcc gccggcgtcc
      601 ggctgctggc cggtggcgtt ctggccgtcg atggtctggt cggccttgag ggtctcccag
      661 agcttgttgg cgtccggctg gaccaggtcg atgttggcgt cctgggtgcg gtagcgccag
      721 ggcgccgtca cgaacttgag gtcgtgcatg tcgatgttct tcagcgacag gccgaaggag
      781 agcagcttgt ccgcggagtc cagccccggg tcgacggtca gcgacttggt ggccgcgtcg
      841 gccagcggca gcagattggt ggggctcagc ccctccttct tcatcttggt ggcgagcgaa
      901 ctcatgaagg cctgctggcg cttcatccgg ccgatgtcgg agccgtcgcc gatgccgtgc
      961 cgcaggcgca cgtagtcgag cgcctgctgt ccctcgacgg tctgcttgcc ctgcgggagg
     1021 acgaggttgc ccttcttgtg caggttgggg ttgatgtcgc cctcgtagat cggcttcggc
     1081 aggcagacgt ccacgccgtt gacggccttg gtcatcgcgg cgaagccgtt gaagtcgacc
     1141 accatggtgt ggtcgacccg gatcccggtg accttctcca ccgtgttctg ggtgcaggcc
     1201 gggttgccgc tgtcgctgcc gccgaccgag aaggcggcgt tgaacaggtc gttgccgccc
     1261 ttggtccact tgccgttggg cagcttgcag gacgggatcg gcacgatcgc gttgcgcggt
     1321 atcgagatgc cgacggcgtg cttgtggtcg gcgtagacgt gcagcaggat cgtggtgtcc
     1381 gagcgggcgc cgccgtcctc gccgccgccg aggtcggagt tgttgccgcc ccggctgtcg
     1441 gagccgatca gcaggacgtt gaccggcttg ttgccgtccg cgtcggcctt ggcctccggc
     1501 gggcggtcgg gggctatcgc gtcggcgtcg aaggacttga tgttggcgtt cagcttgtag
     1561 tagatcgccc cgccggtccc cgcgatcagc accagcacgc cggccgccga ccaggcgacg
     1621 atcttcttca cgttcttctt gggcttggcg ctgcgccgcg cggccgcccg gccgccaggc
     1681 ccaccgtcgg ccttgccgcc gcccttgccc tgcgcggcac ggcgggcctc ggcccggccg
     1741 ccggagcgcg gcgggggcac ggcgcccgct gcaccttccg ccgggagcgc gtcgggcgtg
     1801 tcctcgcccc gagccgggct ctcgcccctc cgacctgaca tgcgcgtacc tttcaccgac
     1861 ggaagcgacg ccccggacga tctggcgcac cgcacagggg gagacgtacc ggaccgctcc
     1921 ctggttgtac gtacgaaggt cggtacggtc cgaccatcat ggcttccgat catattgaga
     1981 ccaaaggtga tcattgacct ccggtacacc aaccacctcg gcagccacgg gacgatcccg
     2041 ctacagaacg accgaaaacg cccgattcgg gcggggtgtc gaacgccgac gtcagaagac
     2101 gcaggggatg ccgccgtcgg actgggcctc gaccttggga ccctgcatcg cgacgttcgc
     2161 ggccgggtcg tccggggccg tgctgggggc ggcgggccgg tcggacgcga cgccgtcgaa
     2221 ggaggtgccg agggtgacca cgacgtggcc ggcgccggcc gaggaggact cggtggcggt
     2281 gaccccgtag cgggcggcga tctggtcggc ggcctccttg gcacccttgc cgtaggtcac
     2341 cgtggtggcc ttcggcttgg tgcgcgccgg gccggtcacc ccctgcttga agcccaggcc
     2401 gaccaggacc ttggcctcgt tggaggagga caccccggcg gcggaggagg cgttgaacac
     2461 gtccacggtg gcgggggcgg cggcctgggt gggcgtggcg gtctgcgtcg gcgcctgggt
     2521 ggcggtcggg tcgccgctcg gggtgtcggc gggggcgggc gcgggggcgg cggcgtcggc
     2581 gccgccgaac acctgcttga ccaccttctg gatcttcgac ggggtgacga tgttgaccgc
     2641 ctccccgccc ttcatgtcct cccggtcgaa ggtcagggtg ttgaactcga cgttgccgcc
     2701 ggtcagcgcc ggggcctgct gggcgaagtc caggacgttc cactcgttgt cgatcaccag
     2761 gtcctgctgg atcactccga acatcttctg catcgccccg aggtcgccga cgacgccctg
     2821 ctccttgagc ttgtgcatca ctccggagat gaaggcctgc tggcggtggg tccgggcgaa
     2881 gtcgtccgag tccccgtggc cgtcgttcag gtggtgccgc tggcggacga aggagagcgc
     2941 ctgggcggcg tcgagcttgc tgcggccggc cgggagcttg agcccggtac cgccaccctc
     3001 gtgggtggtg gtcctggcga tgatcgggtc gtccaccggg tgggtgaggc agacctcgat
     3061 cggctggagc accttggcga tgtcgtagaa gcccatcagg ttgacctcgg cgatgtggtc
     3121 caccggctgg tcgacgaact tctgcacggt gcggatggtg gccgcgcggc cgacgtcgcg
     3181 gccggccttc tccaggtcgg cgcccttgag ccccttggcc ttcgggctgt tgttgaacgc
     3241 ctccttggcg ttgccgtagg cctccttgat cttggccatg cccatctcct tgccgtcccc
     3301 gtcgtaggtc atgacgtagt cgtcgcgggg gatggagatg ccctgcacct tgccgccacc
     3361 cgccggtatg tgcagcagga tcagcgagtt ggtgttgtag ccgccgatgc tggagtccgc
     3421 cccggcgtgc aactcgttct ggacgatggc cgggtcgacg tccgaaccgt ccatgttctt
     3481 gcggctgtcc aggccgatca gcagcaggtt gaccgagttg tccaggtgct tgggggcgtc
     3541 cttcttggtc tgctcgatga cgctggacgt ggtcatcccg tccgtgaggg acgtgtactc
     3601 gtaccagacc accccgctgg ccgcgaacac cgtgaacccg accgtgcagg ccaccacccg
     3661 gccggcgatc agcagcgggg agcggccccc gccggaggcc ttgcgggcgg cggcgcggcc
     3721 gccccgcggc ggctgctcgg cgtgcggcgg ctgctcggtg ttctcggcca tggctccccc
     3781 ggtcccggac cgacggtcgg cccgtcctcg acaggtctgt cgcggcccag cgaagcacag
     3841 aatcggatca agccaaagca gttcgacgtc ggattgccat caatcagccc gttttgacgg
     3901 gtgatcaccc cgccccggga gccggctcag agccagccgc gccgccccgc cagcaggccg
     3961 gcctcgaagc ggctgcgggc gccgaggcgg tccatcagat cggccatcat ccggcgggtg
     4021 gtgcgcagcg agacgccgag gtgcttgccg gccgcctcgt cggtgtagcc ctggccgagc
     4081 aggcgcagca gttcctgttc ctggcgggtg aggccctcct cgtcgcgttc gcacggggcg
     4141 ccgaaggggg tggcgtcgga ccagatctgt tcgaacagcg agaccagcgc cgcgagcacg
     4201 cccggtgacg agatctggac ggcgcccttg agggtgttgg ccgggtcgat cgggacgagc
     4261 gcgacctgcc ggtcgatgac cagcatgcgc agcggcagcg cgggcaccgt ccgtatctcg
     4321 cagcccagtc cggtcagcca ctcggcgtgc tggacggtgg cccggtcctt gcgcaccacg
     4381 tccaggtaga cggtgcgcat cgtcaccccg cgggcgagca gcttctcgtt gtcggggcgg
     4441 ctggcctgga gcgaggcgac ggaccgggcg cggccggggg cgaaggtgag cagttcctcg
     4501 cggaccgagc cgaccagttc ctccatcctc gcgtgcacgg tggccgtgcc gagcagccgc
     4561 tccagttggc tgtcctcggg ggccgactcg tcgcggaact gggcgagcat gccggagatc
     4621 tcggcctggc gctgctcgaa ctccaactgg gcgcgctgct ggacggattc gtagtaccgc
     4681 agcagggccg gcagtccgac cctcgggtcg accggccgca ggccgccgga cggctcgccc
     4741 ggagcttcgt ccccggaggg ttcgaagggg cggagcaggc gcaggccggc gagctggtcg
     4801 agggcggccc ggacctgctc ctcggtcagg ccgagctttc cggccagacc ctcgacatcc
     4861 agctgatggt cggtcagcat caaccgatag accgcctgcg cggcatcgtc gatctcccgc
     4921 gtcatcggcg caccactccc ccgcagcccg taccgatttc cggcccctgg ccggacgaag
     4981 cccgctgccc gatcatgcca ggacggacag gtcaggacaa ccgcgtatgc ctttcccccg
     5041 ggggccccgg atcggccggt cgcgataaag gtcatggggc ggcaatggca ccaaggtgcc
     5101 acggtgatct tcctgccgcc ccgaacacct tccgatagcc ctcgacttcc tccagacttt
     5161 cggttgtcgg ggagccgcga gctccccagc cgggcccgcc gatgaccacg gaccgtcatc
     5221 accgatggtc gaccgacgag gtcgtggaac cggccggcac ccgcttccga aacacacatg
     5281 tcctggggga cctccatgtt gatttcctgc cgcacgttcg cctgtaccgc tgccgccgcg
     5341 ctggctgtcg ccggtggcgt cctggccgga tccgcgcacg ccgcgcctgc cgccggcccc
     5401 accaccgcct cggtgcagca gttcacgaac cacctgccca cccagccgcg ccagccccag
     5461 ctgccgacgc tcggcggcgc cgcgaccccg ggcgactggc actggtgacg gtcgcttccg
     5521 caggccacgg cacctgactc cttcctcgcc acgaccggac cgacgggcag cccggccgga
     5581 cggtgacgaa ggtccgtcgg cgggacttcg gaccgccgca taaattgaat gtgcaacaaa
     5641 ccgccaggag caccagtgcc ggttatcgag ccgattgtgc tgaacttctt cggcctcgag
     5701 atcgccctcg tccaggccga ccgcgacgag atctcgttcc atttcggacc gcacctcacc
     5761 gggatttccc gggatcccga ccaactgtgg gtggaattct cccggacccc ggggaaggac
     5821 gctcccggcg atttcctggt gcgccgcagt gacggaacgc cattgctgcg gcgcaccttc
     5881 cggggctggg ggaacgtccc gtccgcggtg ccgccgttcg cggcgctgca ggaccggttc
     5941 tgcctggccc aggccgtggt gctggccaag ggcggcgcca ccgtggcgct ggtcggcgga
     6001 ccgtactcgg agcaggccaa cgtgggcgcc gcgctggcgc agcgctcctg ggagttcgtc
     6061 tccggacggc tgctggtgct ggaccgtcgc accgggcacg tactgcccta cctcgcgccg
     6121 ctggaggcgc gcggaccggc cgcggcctgg ctgcgcggcg ccgggctgcc ggacgggatg
     6181 tggcgcaccg tcacctcgcc ggtcggcggc gaggtgctgc tggtgcggcc ggagagcctc
     6241 ggcccggtgg tgccggtgcg ggcccggctg gctccccctt cgctggtccg gctctgccgc
     6301 agcatcgacg aggaagtccg gctggcacca tgggagttca cgacccacac ctggccggcc
     6361 gggtccagcg gggcgctcgc cggggcgccg acccactgcc tgcacctgcc cggcgtgagc
     6421 ggggcggagg aggcggccgg tctgatcgat caagccatga ccaaggagaa ggacgagccg
     6481 tgcctcgacg taccagctat gccatcggcg ctccgtgctg ggctgactgc atcactcccg
     6541 atctgagcgg cagccgggag ttctactcgg cgctgctggg ctgggagttc gtcaccgagt
     6601 cgccggacta ccagctggtg gtgctgggcg gggagatcat cggtggcttc ggcgccgccc
     6661 cggtggggtt gccgccgcag gccgcgtgga acgtctacct ggcgaccaag gacgcggagc
     6721 actgctgcgt gcaggtcggc cggctcggcg ggcgggtggt gatgccgccg gtgcccgccg
     6781 gggagaacgg gcggctgctg ctcgccgtcg actcctccgg ggtcacggtc ggcttctggg
     6841 agggcgcgcg ggccgagggc gtggtgctcg ccgacgaacc gggcgcgatc tgcggccacg
     6901 agctgcgggt gccgtcggcc atccaggccg aggccttcta cgggccgctg ttcggttacc
     6961 ggctgggcgc ggacgggcag ttcgcggtcg acggcttcgg ctacgcccgg gtggtggaga
     7021 gcgaccaggg ccgtccgtgc tggctgccgc tcttcggcgc ggccgacccg gcggacgccg
     7081 tccgccgggc ggtcgggctg ggcgcccggc tggtgcggcc gggcgcggag gagccgccgg
     7141 tgctgcgcga cccgtggggg gccgagttcg gcctggtccc cgcttgatcc acgacgtcgc
     7201 tacaacgcct tgaccgcggc gcccagttcg ggccggccct tgatcgccag cttgcggtag
     7261 atccggccca ggtgggtgtc caccgtgcgc ttgctgaggc agagccgctc ggcgacctcc
     7321 aggttgctca ggccctgcag caccagctcg gtgacccgcc gctcgctcgg ggtcagccgg
     7381 accgggccgg cgtcgcgggt gccgatggcc gggccgccgc gctcctcggc cgggcgtggc
     7441 cgggcgtcgc cgccgggcag cgggtcggcc gcgatggtcc gggcggcggc gtgctcgccg
     7501 agcgcctggt aggcctgcgc cgcgtggctg cgccacggca cgcaggccgg gttggccacg
     7561 ccgcgggcgg ccagctggtg cccgcactcc aggaagagcc gcagcgcctg ctggtggtcg
     7621 ccgcggtgcg cggcgaccag gccgcgggcc tccagcacca ccgcgcgcag caacgggtgg
     7681 gcctcggcgg gcagttcgac cgcggccggc tcggcgtcgg cggtcgcggc gtccaccggc
     7741 agaccccggc gcagccgggc ccgtacggcc agcgcccgcg cggcgcccgc gaggtcctcg
     7801 gcccggatcc gccgggccag ttcggcggcc tgttcggcgt cggcgagggc ggcgtcgagc
     7861 cggccctgcc ggtgggcgat gtcggagcgg gccagcaggg cgagggcgag ttcgccgcgg
     7921 tggttccagc gctgggcgga gcggaccacc cggccggccc aggcggcggc ttcgtcgagc
     7981 cgcccggtcc aggcgtaggc catcgccgca cccagcacgt ccgtcccggc ctcggcgggc
     8041 gagacccgcc gcacgcagcg cgccgccagc cgcaccgccg tacggggctg gcccccggcg
     8101 gcggccagcg cggccagggc gccgagcatg ccggtggcgg cgggctcggc ggggtgggcg
     8161 cgcagggcgg cgagggcggg tcgcagggcg gtgcgccgac cggtcagcac ggcctgggcg
     8221 gcgagcggca gcagcagttc ggcggggggc gcgggggtgc cggcgagtgc cgcggcggcc
     8281 tcggcggagg ggacggcggc ggcgccggcg gcgctgagcg cgagcaccgg gccggcgaac
     8341 ggccgcagca gccgggcgcg ttcgaccggg tcgggggcgc cggcagcgag gccggcggcg
     8401 cagcgggcgg cggcggccac gtcgcggtgg agttcgacgg tgccgagctg cccggtgagc
     8461 gagcggacca gttccgggtc ggcggcgtcg gcgagggcgc gctggaggta gcgggcggcg
     8521 tcgtcccagt ggccgtcggc ggcggcttcc cgggcggcgg tgcgcagcac cgggacggcc
     8581 cagtccagcc cggtggtgcc ggaggacatc aggtgttcgg cggtgcgggc ggccggggcg
     8641 ccgagccggg cgagcagggc ggcggcccgc tcgtgcaggg cgaccaggac gcgcgggtcg
     8701 gtgcgggcca ggacggcggt gcggaccagc tcgtgccgga aggtctccgg cggaccgggt
     8761 tcgatcaggt cggtgcggcg cagcgcctcg cgggcctcgt cggcgaggag ttcgccctgg
     8821 ccggtgagca gagcggcggt ggcgaggtcg gcgtcggcgc ccagcacggc gaggccggtg
     8881 agcagttcgg cggcgcgggg gtggctctgc cgcagccagc tgagggtggt gtcggcgagg
     8941 gtcccggcgc cgatccgcag caccttgtcg aggtcgggcg agccgggcga gatccgggcg
     9001 gcggcgagcc gggcggtgag ttcctcgacc accagtgggt tgccccggga gaggttgtgg
     9061 cagacggcgg cgagttccgg gtcgaccggg gcgtcgaact cctcggccac caggtcggcc
     9121 acgcagctgt cgcagagcgg gccgggggtg agggtgcggg cgtgccggag cgcggcgagt
     9181 tcggcggcca gcgggtcggc cgcctcgtcg gcggtgctgg cgagcagggc gacgggcagg
     9241 ccgtcgagcc ggcgggcgag gtaggagaac cactgccggg actcctcgtc ggccaggtgg
     9301 aggtcgtcca cggccatcac cacgggtgtt cgtgaggtga gcgaacgggc cgcgtggaaa
     9361 aggttgttca ggacccgttc gcgcccgttt ccgacacttt cgggacccgc cggatgtgcc
     9421 gtcggggcgc ccccgggaag ggcctccgga agggcctcgg cgaggaattc cccgggcgat
     9481 tcgcccagga attgcggggt cgcctccggg ttgtttgtca tgcgcatgaa aggatcgaag
     9541 agctgacgga ccacgccgta cggaaagtcc cgctcgttgt cgtgacatcg cgcccgcagc
     9601 accaccgcct cgcccggcat ccgggccagc gcggcgcgca gcagcgcact cttcccgatc
     9661 cctctcgggc ccctgaccag cacgaccgcg gaacggcccg cgccggcacc cgccaccgca
     9721 cgcgccagct ccgccagctc cgtctcccgg tgcagcaaaa ccccagtcgg caccgcaacc
     9781 ccccgtcata ccccgtcgcg cggacacacc agtatcgcct gcggcgcccc cctgtcaacg
     9841 ctccggccga atacgtacgg gactacgtac cggtccgacg gaatacgcaa ttccgcgcga
     9901 tgcgtaactc gaccgccccg ccgaatatgc agtatgtaca ggccatttga cgccgtgttc
     9961 gaatactcgc aacgaacttg tgaacacagg gggatgactt atggagcgtc cgcggctcaa
    10021 ggcccatttc ctcaccgaga cggtgggcga aaaggtcttc ctgctcggag aggggcagga
    10081 ctacctcgtc ccgggagccg ccgcggtgcg cctcctgccc tacctggacg gacggcgcac
    10141 cgtcgccgag atcctccagg agctcggcgg cgagatcggc ctcggtcagg cgctgaccgc
    10201 gctgcgccgc tacgaggcgg ccgggcacct cgccgagggc cggcccgacc tgcccgacca
    10261 cgtgctcgcc tactgggacg cccagggcgt cgacccggcc gtcgcgctgg cggccgcccg
    10321 ggccaccgag ctgctggtgc tcgccctcgg cgccgccgag gccaccccgc tggtcgaggc
    10381 gctgaccgcc accggcctgc gcgcccgcgc cgtcaccgag gaccaggccg tcgcggccgg
    10441 cccggacacc ctggtcgtcg ccctcaccga cgactacctg gaccgcgccc tggagcggct
    10501 gaacaccgcc cggctcgccg acggccgccc ctggctgctc gccaagccca ccggcacctc
    10561 cccctggctc ggcccgctgc tgcgccccgg cgagaccggc tgctggagct gcctggccca
    10621 gcggatcagc ggcaaccgcc aggtcgagcg gtacctggcc ggcaagcgcg gcgagaccgt
    10681 gccgctgcac cccacccgcg ccgcgatccc ggccggcccg gcgatgaccg cccagctgct
    10741 cgccaccgag gccgcccgca tcctggccga cgagtgctgc tccgcgctgt ccggcaccat
    10801 ggtcagcctc gacctcaaca ccctgcagac caccgagcac accctggtcc gccagcccca
    10861 gtgccccagc tgcggcgacc cggcgctgct caccgagcgc agccccaagg tcgtcctgca
    10921 gcccagcccg gcccggcaca ccaccgacgg cggctaccgc gtccaggccc cgcagttcac
    10981 ctacgaccgg ctcaagcacc acatcagccc gcacctgggc gcgatcaccc gcctcggcgc
    11041 gcacgaggac accggcaacg gcatcaccta cagcttcacc gccggccaca acttcgccat
    11101 ggtcaacgac aacatggacc tgctgcgccg caacatgcgc ggccagagcg gcggcaaggg
    11161 ccgctccgag atccaggcca aggtcagcgc gatctgcgag gcgatcgagc gctactcggc
    11221 ggtctggcgc ggcgaggagc cggtggtgcg cgccgcctac cgcgacctcg acccggccgt
    11281 cgccgtccac atggacgccc tgctgcagtt ctccgacgcc cagttcgcga accgcgccga
    11341 gtggaacgcc gaccccaagc accggctcca cctggtgccc gacccgttcc cggtcgacgc
    11401 cgaactggac tggacccgcg cctggtcgct cacccacgac gaggagcgcc tcgtcccctc
    11461 cggctacgcc tggtacggcc accccgacct ccagcagcac ttctactgcg tcggcgactc
    11521 caacggctgc gccagcggca acaccctgga ggaggcgatc ctgcagggct tctgcgaggt
    11581 cgtcgagcgc gacgcggtcg ccctgtggtg gtacaaccgc accgcccagc ccgagttcga
    11641 cctcgactcg ctgaacgacc cgtacgtgga caccatgcgc gccttctacg cctcggtgga
    11701 ccgcgagctg tgggtcctgg acatcacctc cgacctcggc gtgccggtgt tcgccgcgat
    11761 ctcccggcgc aagcacgagg tcgaggacat catggtcggc ttcggcgccc acccggaccc
    11821 gaagatcgcc gcgatccgcg cgctcaccga ggtcaaccag ttcctcccct tcgtcgaccg
    11881 gcgggacgag aacggcaaca ccctgtaccg caccgacgac ctggagaccc tggagtggtg
    11941 caggaccgcg acgatcgcgg gcgagccctg gctgctgccc gaccgcgccc agcccgccag
    12001 caccctcgcc gacttcgccc cgctcaccgg tgacgacctc gccggacacg tccgggactg
    12061 cgtcgagcgc gcccgccggg ccggcgtcga ggtgatcgtg ctcgaccaga gccgccccga
    12121 cctcgacctc gccgtggtca aggtgatcgc ccccggcatg cgccacttct ggcgccgcct
    12181 cgcccccggc cggctctacg acgtgccggt gcgccagggc cgactggccg ccgcgcacac
    12241 cgaggagcag ctcaacccga agaacgtctt cttctaggaa cggccgggtg cagacgagat
    12301 gaccaccgcc acgacccccg cgacggccac cgccctcgac gggatcgacc tgcccgccac
    12361 cgcccgtacg gtgcgccggc tgcggctgcg ccccgacggc gcgctcaccc cgctcggccc
    12421 caaggccgtc cggctgaccg cgccggtcgg cgcgctgaac ctgcccgacc tggcgcccgg
    12481 cgccatggag gcggtggccg cgctggccgc cggggagcag accgaggagg aactggccgc
    12541 cctggtcgcg gcccgggacg gcgacgccgg gctgctgcgc tggcagctga cccgccgccg
    12601 gctcggcacg gccgggatgc tggagcactc cgtccacttg gtgctcgacg gtgcggacga
    12661 gccgctggcc cggctgcgtc cggtcggccg gggcgccgcc gagccggggc ccaccccgga
    12721 cccgaccggg caggtgaagc tgtcccgctt cgcctccgcc tcggtcgagg gcggcgccct
    12781 gctggtgcgc gccccgggca gcccgctggc cgtccagctg accacccggg ccgccggcct
    12841 gctggccgcc ctggccggct ggaccagccc cgccgcgctc gcccaactcc ccgacgggct
    12901 cccgctggac gccgtccggc agaccctgcg gctgttcgcc gcggccgggc tgctggccta
    12961 cggctccccc ggcgccgagc cggaggccga ggagcagcgc ttcgcccagt ggacggccgc
    13021 cgacctcgcc ttccactccc gcacccgccg gcccaccagc gtggccgggt acggcggcac
    13081 ctaccggttc ggcgaccgct tcgcccccga gccggcctcc ccggcgccgt tcgcgggccg
    13141 caaggtcgcc ctgcccgtcc cggacctgga cgaactcgcc cgagccgacc ggccgttcac
    13201 cgaggtgctg gagcagcgcc gctcggtgcg cgaccacgac gagcagaccc cgatcaccct
    13261 ggagcagctc ggcgagctgc tctaccgcag cgcccgccgc cggcagacct tcaccggcgg
    13321 ggacggccag gagctggccg accggccgta cccgagcggc ggcgcggtgc acgagctgga
    13381 gctgtacccg ctggtgacct cctgcgcggg tctggagccc gggctgtggc actacgcgac
    13441 cgaccggcac gagctggaac tggtcagcga gccgagcgcc gcgaccgccc aactggtcaa
    13501 gagcgcccgc gagtccagcc tgatgcagac cgatccccag gtggtgctgc tggtcaccgc
    13561 gcgcttcggc cgggtgatgt ggaagtacga gacggtcgcc tacccgctga tcctcaagca
    13621 cgtcggcgcg ctctaccaga ccctctacct ggtcggcacc gccatggacc tcgcggtctg
    13681 cggcctcggc ggcggcgacg cggccgactt cgccgcggcc agcggcctcg actacttcac
    13741 cgagggcagc gtcggtgagc tggtcatcgg cagccggccc ccgacgctgc gccaggacgt
    13801 cggcgtccca cggagagaag caagacgatg aagttccgtt tcaaggcgct gcagcggatg
    13861 cgcgagccgg acgagctcga ctcgccgacc ctgctcgccg cgccccgggg ctggatcgcc
    13921 ctgttcgtcg tgatgatcac catggccacc gcactgctgt ggaccttcac cgggaagatc
    13981 ccgatcaccg tggacgcccc cggcctgctg acccacccgc acggcaccgc gatgatccag
    14041 agcccgttcg gcgggatggt ccgcacggtg ctcgccaagc ccgccgacca ggtccggcag
    14101 ggccagtcgg tggtccgggt cgaggacacc gagggccaca gccgggagat caccagcccg
    14161 ttcggcgggc gggtggtcgg cctgtcggtc accgacgggc aggtggtcgc ccccggctcg
    14221 ccggtcgcct cggtcgaacg ggtggacgac ccgaaggagc ggttggtcgc gatggtcttc
    14281 gtgcccgcga cccgcaccgt cgggctcggg cccggcgacc aggtggacct caacgtgtcc
    14341 accagcccgg ccggcgcctt cggcctgctg cgcggcacgg tcagctcggt cagcccgtac
    14401 gcgctcacca aggaggccgt ctccggcctg gtcggcggcg acctcgccgc ccagcgctac
    14461 ctcggcaagg acgcgccccg gctggtcgtc gtcgacctga cgcccgaccc cgacaccccg
    14521 agcggcttcg cctggacctc gcagagcggc ccgccgaacc cgctgggcac ccaggtcgcc
    14581 gtcaccgcca cgatcaacgt gggccggcag accccgttca acctgatcct cggccgctga
    14641 gagggggctc cgatgacagc cacgatcccg gagaccaccc cggcctccgc tcccgcaccc
    14701 gaaaagaagc cgcgccgcgg ccgccccacc cgggcggccg cgccgcggcg ctggcggcac
    14761 gccgtcccga ccgtcctgca gatggagtcg gtcgagtgcg gcgccgccag cctcgccatg
    14821 atcctcgccc accacggccg ttgggtcccg ctggaggacc tgcgcggcgt ctgcggggtc
    14881 tcccgcgacg gcgcccgcgc ctccaccctg ctggaggccg cccgcacgta cgggctcaag
    14941 gcccgcggct accagaccga ggccgagaac ctccgcgacc tcgacggccc ggtgatcatc
    15001 ttctgggcct tccagcactt catggtggtc gagggcgtcc gcacccggta cggccgcacc
    15061 gtcgtcgccg tcaacgaccc ggccagcggc ccccggctaa tggagtggga cgagttcgac
    15121 tccggcttca ccggcatcgt gctctccttc gagaagggcc ccgacttcga gcccggcggc
    15181 gacaagggcg gcatcggccg cgccctgctg gagcgccggc tgcccaccgg gcgcgccatg
    15241 ccgctggtgc tgctcgccag cctgctgctg gtgctgcccg gcatcgcgat ccccgcgtac
    15301 acccgggtgt tcatcgaccg ggtcctggcc ggcagcggga gcggctacct cctcccgctg
    15361 ctggccgcca tgaccgccac cgccgtggtc gtcttcgtgc tgacctccgt ccagcggcac
    15421 tacctgctgc ggatcgagat ccggatgggg ctggtcagct ccgcccggtt cttccggcac
    15481 ctgctgcggt tgccggtcga cttcttcctg cagcgccgcc cggccgaggt cgccaagcgg
    15541 gtctccggca acgacgtggt cgccgagatc ctctcccgcg acctcgcgct caccgtgatc
    15601 aacctcggcc tggtgctgtt ctacgcggcc gtgctgatcc gctacgacct gctgctcggc
    15661 gtggtcggcg tcggcatggc gctgctcaac gtcgtcgtgc tgcaggccgt cgcccgggcc
    15721 cgcaccgacg cggtcgccgc gctgcgcacc gaccgcggca acctcaccgc gaccaccttc
    15781 accacgctct cgctgatcga gaccgtcaag gccaccggcg ccgagcagga cgccttcggc
    15841 cgctgggccg gcttcctggc caaggtcgtc accgccaagc agaagctggg catccccagc
    15901 gccgtgctca ccgtggtgcc gccgatgctg gccgcgctga acagcgggct gatcctgctg
    15961 gtcggcggcc agcgggtggt ggacggcgcg atgagcgtcg gcatcctggt ctccttccag
    16021 accctgctgg ccgcgctcag ccgccccgtc acccagctca ccaacctggg cggccggctg
    16081 caggacgtca cggccgacat caagcggctg tacgacgtcg agcgctaccc ggtggccgcc
    16141 gccttcgcca ggcccgagcc gccggccggg cccaagctgg acggcaccct ggagttcgag
    16201 gacgtccgct tcggctacag cccgctctcc gagccgatca tcaaggacct cagcctgacc
    16261 gtcgtccccg gccgccgggt cgccgtggtc ggcggctccg gcagcggcaa gtccaccctg
    16321 ggccggctgc tcaccgggct ctacaccccg tggtccggcc ggatcctgct ggacgggcgg
    16381 ccgcgcgagg agatctcccg caccgtgctg gcctcctcgc tggcctacgt cgaccaggac
    16441 atctcgctgt tcgagggcac cgtccgggac aacctgacgc tctggaacga cgacgtcccg
    16501 gacgaggcgg tcaccgccgc gctgcgcgac gccgccgtct tcgacaccgt gatgacccgg
    16561 cccggcggca tccacagccc ggtgctggag ggcggccgca acttcagcgg cggacagcgc
    16621 caacgcctgg aactggcgag ggcgttggcc agcgagccga ccctgctggt gctggacgag
    16681 gcgaccagcg cgctcgaccc ggagaccgag cgggtgatca tggacaacct gcgccgccgc
    16741 ggctgcgcct gcctgatcat cgcgcaccgg ctctccaccg tccgcgacgc cgacgagatc
    16801 atcgtgctgc aggagggctc gatcgtcgaa cgcggcaccc atgacgagct gttggcgctc
    16861 ggcgggcact acaccgcgct catcgagtcc gcgcgccgcg aggaggagga cgaactgtga
    16921 gggagcgaag cgagcgaacc atcagaaggt gcgagttgag cgaagcggct gccgagcggt
    16981 gggggtcccc ccggccggag gctgggggag aggtggacgc atgagcactg ccgtggaggt
    17041 cttctcgccg atactcaccg aggcggccga gccctcgggc gaacgctacc tcgtgctgga
    17101 cgaccccgga cggctgctgc tggtccgctc cggcgccgtc gacctgttcg ccgtccagct
    17161 cgactccggt gcgccccaag ggcgttggca cttcctctgc cggatcgagg cgggcaccct
    17221 ggtgcccggc acggcggccg ccggggcgcg gcgcggcatc gtcgcccggc cggtgctcgg
    17281 cgccgaactg tccttcctcg ccacttcccg ggtcgagggg ctgctcggtg ccgcgtccgg
    17341 cggcacctcc ggagccgccg accagttcct caccgggctg gcccgcggcc tcaccgcgct
    17401 cgccggtgcg ctgcgcgaca ccctgccgcc acgcgagttc accccgctcg accccgtcga
    17461 gccgaccgtc ctgaagcgcg gccaggcact gcgctcggtg gacggcctgc agtgggtgcg
    17521 ggtcgagcag ggcagcgtcg aggtgcccga aggctccgac ggtgaactca ccgaaggcgc
    17581 cgaggtgttg ctgaccgaac gggactggct ggtcgccacc ggcccggcca ccgtacgggc
    17641 ccgctccccg cgcgaactgc tcgaccaggg cggcctctgg gagcgcctgg ccgcccactg
    17701 cgggcggctg ctggacgccg tcgaccgccg gatcgaggcc cgccgcaccg ccgagaccga
    17761 gctgatcgcc acccgccggg aacgcgacgc cggcaccctc gccgactccg cccgcggctt
    17821 cgagaccatc ctgcgcgaca ccgcctcccg gctgcggatc ggggacgcca ccggcgacga
    17881 gccgaccctg gccgccgccc ggctggtcgc cgcccacgag ggcttcaccg tcaccgcccc
    17941 ggtggccggc atcggccacg accgccggct cgaccggctg caggcgatcg cgttggcctc
    18001 ccacgtccgc acccgctccg tccgactgga cggcaagtgg tggcagaacg acctcggcgc
    18061 gatggtcggc taccgcaagg ccggcgcccc ggtcgccctg ctcccgctcg gcaacggcta
    18121 cgtgctggcc gagggcggca aggtcacccc gctgaccccg aagctcgccg ccgaactgca
    18181 gaacaaggcc accgtgctct accggccgct gcccgccgcc gtgcgcaccg tcgccgggtt
    18241 gctccgcttc ggcctgcgca acaaccggca ggacctgtgg atgttcaccg ggatggccgc
    18301 cctggtcgcg ctgatcggcc tgctcgtccc ggtgatgacc ggcgaggtgc tcggcacctt
    18361 cgtcgcccac gcccagcgca acctgatcac cgagggcgcg ctggtggtga tcggctccgc
    18421 gatggcggtg gccgcgctgt ccatcgtgca gaacatcgcg gtgctgcgga tcgagagccg
    18481 ctccaccgcc gccatgcagg tcggcgtctg gaccaggctg ctgtcgctgc ccgcgccgtt
    18541 cttcgccgac tactccaccg gcgagctcgg caccacggtg ctcggcgtca gcgccgccca
    18601 ggagaccctc tccgggatga tgaccacggc gaccctcggg ctgctgaccg ggctcgccaa
    18661 cctggtgctg gtctacttct acgacctgcg actggccgca ctcgccaccc tgctggtgct
    18721 ggtcggcgtc ggcgtcggcc tggccgccgg gcggctcgag gtccgctggc agcgccggct
    18781 gtacgcccac gagcaggcga tgtccgcccg ggtcttccaa ctgctcaccg ccgtacccaa
    18841 gttgcgcgtc accgcggccg aggaccgggt gttcggggtg tgggccgccg aactcggcaa
    18901 gggccgcggc ctggccgcct cctcgcgccg ggtgcagaac gccgtcacca ccttcaacgc
    18961 cggtttcccg ctggtgtgtt cggtggtcat cttcggcgtc atcgccggcc cgctggacgg
    19021 cgacgtgccg atcccggtct tcctctcctt cttcaccgcc ttcaacctgc tgatcgcctc
    19081 cagcctccag ttcacctcgg cggccgtcac cgcgatgggc gtcgtcccga tgctggaacg
    19141 gctgcggccg atcctcgagg agaagcccga ggtcgacgac accaaggccg accccggcga
    19201 cctctccggc cgcctcggcc tcagccacgt caccttccgc tacggcgagg acggccccgc
    19261 cgccctccag gacgtcacgc tcagcatcga acccggcgag ttcgtggcga tcgtcggccc
    19321 ctccggcagc ggcaagtcca ccgtgctgcg gctgctgctc ggcttcgaac ggccggagag
    19381 cggcaccgtg ctgtacgacg gccaggacct cggcgaactc gaggtctccg ccgtacgccg
    19441 ccagtgcggc gtcgtcctcc agcacggcgc cctgctcgcc ggcgacatca aggccaacat
    19501 cgtcggctcc accaaccaca ccctcgacga cgcctgggcc gcagccgaga tggccggcat
    19561 cgacaaggac atcgcggcca tgccgatggg catgaacacc gtcctctccg aaggcaccag
    19621 caccctcagc ggcggccagc ggcaacgcct gatgatcgcc cgcgcgctcg tctcgcgccc
    19681 ccgcatcgtc ttcttcgacg aggccaccag tgcgctggac aaccccaccc agcgcctggt
    19741 caccgaatcc acccgccggc tcaacgcgac ccgggtggtg atcgcccacc ggctgtccac
    19801 cgtcgccgaa gccgaccgga tcatcgtgat ggaccagggc cgggtggtcc aacagggccg
    19861 ctacgaggaa ctgttggccg accgggacgg gctgttcgcg cggctggcac accggcagat
    19921 gtagtaggta agcggagaag agagaacgat ggaatacacc ctgctcattc acggcgacga
    19981 gcgggtctgg aacggactga gcgaggccga acaggccgaa ctcgacgccg cccacgtgcg
    20041 gttcgggcgc gcgctgcacg aggccggggt caccgtccgc tacggcggcg ggctgcggcg
    20101 cagctgcagc gcccggctgg tggtgcccgg cggcggcgcc gggacaccgg tctcggacgg
    20161 gccctaccgg gaggggcacg aacacctggg cgggctgtgg gtcatcgacg tcgcggacga
    20221 ggcggaagcc gtgtcctggg cccgctggat gcccgcggcg cccggcgacc tggtcgaggt
    20281 ccgcccggtg cgggtgatct gagcccgagg agagaggccg aggaggcccg cgcccgcgtt
    20341 gaagggcgcg ggccttcccg tgattcctcg atgcatcgtc aagcccttgc gttaacggac
    20401 tgtttcacat gcaatcaatc gcggcacacc ccttgcccgg atcatgacag gtcggcgatc
    20461 ctgtactgcc gcccctcaac ggtcgcccca acggcccggg ctggcgcttg aacctcctgc
    20521 tcgtccccca cgaaggagcc agcatgcgca gattcctgat acgcgtcgcc accctcgcgg
    20581 ccgcagccac caccctcgcc gcccccgccg caccgaccac cgcggcggcc gcccagggcc
    20641 tctcgttccg ccccctgcag tacaacacca acggctacaa ctggggcggc tacgccgcca
    20701 ccgggagcgg cttcacctcg gtctcggcct cctggaccga gccggacgcg acctgcaact
    20761 ccaccaacga cctctacgcc ccctgggtcg gcatcgacgg gtacggctcc tcctccgtcg
    20821 agcagaccgg agtcgccacc gactgctcca gcggcagccc ggtgaaccag gcctggtacg
    20881 agatgtaccc gtcgagcccg gtctacctga gcctcagctc gtacccggtg tcggccggcg
    20941 accacatcag cgcctcggtg acctacatcg gaagcagccg ctacaccctc aagctcaccg
    21001 actccacccg cggctggacc tacagcacca ccaagtccat ctccgcgcag cggaccagcg
    21061 ccgaggtcat catcgagtcc ccgaccgggt cctaccccaa cttcggtacg ctgaccttca
    21121 cttcggccac cgtcaacggc cggtccctcg gctcctacaa cccggtcgcc ctcgacccca
    21181 gctccaacgg cgtctacgag gccagcacca gcgccctcgg ctccaacggc accagcttca
    21241 ccgacacctt cctggcggag tagccatcgc atcgaggagc gggaagtcgg ccgggccgac
    21301 ttcccgctcc tctgcgtttc agggggtgga ggtcggaggt gaagtgggtt gccggctcgg
    21361 acggttgtgg ccaccgctcc aggcgagcag cgcgagcagg agcgcgaagg gcaggagggt
    21421 gcagaggatc gcgctggagg ggtgctgaag gctgtcgcgg acgacgtgat gaaggcgaag
    21481 gtccgggtgg ccacgaggca cccgtgacgt tcgccgccac caccgaggcc tgacccaggc
    21541 ctcctctcaa cggcccacca ccatccgggt gcccagtacc ctgctggagc gggccgacga
    21601 gccgagcgcc cgcgcctgcc cggtctgcgg atcgggtgcc acctaccaga ccatggacgg
    21661 ccgatggggc tgcaccgcgt gcggctccac ctgggcctga ccccggggag gacccgatgg
    21721 cggcctgcac ccagtgctcc gctcctgcgg cgatcgagga tctcgacgtg cagccgcccc
    21781 agccctggtg cctcggatgt gcgaccaccc tcgtgcgggc cggcgatccg gtgctcaact
    21841 accgctcgct caacggcgag agtgagtacc agcgcgtcct gaccggcggc agcacccagg
    21901 tcctgccctt cggctgaccg gcacatcgaa gcggcctgct ccctgccgtg gcagggagca
    21961 ggccacactc gtacggcttt cctactgatc ccgcaaagcg gcagcgtggg tcactgcggc
    22021 ggcgaggagt gcaacgcatc ctccgagcag catcaccacc gacggcgagg aggtatcgac
    22081 gacggcgccg ccggccaggg cgccgagcga gatggtggcc tggaaggagg acgtgaagat
    22141 gaccgtggcc gcttctggtg tgtccggggc cgcgcggacg aaccacgctt gggcgcagac
    22201 cgggacggcg ccgtaggcga ggccccacgc gacgaggagc aacgctgcgc ccggccaggc
    22261 cgtgccgagg acggggagga gcaggacggc ggctgcgagc aggctgatcg cgatggtgaa
    22321 cgtggcgcgc cgccccgccc agaggccgcc gacgaagttg cccgcgacgc ctgcgattcc
    22381 gtacacgagc aggagcgcgg tgacggcgtc cgggccggcg tgggtgacgt cctccaggaa
    22441 cggcgtgacg taggtgtacg tgccgaagtg ggcggtcacc aggaggaggg tgatggcgag
    22501 gccggcgcgg acggcacggg tgcggagcag cccgcgcagg acggcgaggc gggtgggggc
    22561 ctctggcggc agcgggggca gggtcgcggc gagggcggcg gacacggcga ggctcagcac
    22621 cgccatggcg gcgaaggcgg cccgccaccc ggccaggtgg ccgagcagga caccggcggg
    22681 cacgccgagg accgagccca gcgggaccgc cgaaaagatc accgtgttgg cccgcgcctg
    22741 ccgctccgcc gccaccaggc gcggggcgag cccggccccg atcgaccaga acgcgccgat
    22801 gacgaccccg agcacgaccc gcgccgcgag caccgcccag taaccggggg cgagcgcgtt
    22861 gacgaggtcg gcgagcgcga gggcgagcat gaggccgcag aggacgcccc gccggtcggc
    22921 ccgccggacg gcgacggtga cgaccggggc ggcgacggcc gcgatgatgc ccggcagggt
    22981 catcatcagc ccggccgtgc cgtccgagat ccggaaggtg gcgccgatcg gggtgagcag
    23041 gccgatcggc aggatctcgg tggtcacgac ggagaagatc cccgtcatca cggaggcaac
    23101 cgctaaccag ccgcgaagca gtccccgagt ggacgtacgg gcagcagcgg gcgaggcggg
    23161 aagggaagtg ctgggcatgc gaccagtcca gcagcggccc caccctggag ctggcgcgtt
    23221 tgcgacgtca acgatcgctg ttccggctcg ctcgacgggg ggaaggcggg atcgctaacc
    23281 tcactggagg tcaaggaata tgacggaacg acacatcaga ggcgcgggaa tgcatcagtc
    23341 gacatggttc atcaccggaa cgtcgtccgg attcgggcgt cgcctcaccg aggcgctgct
    23401 ggagcggggc gaccgggtgg cggcgactct gcgcaggccg gacgggttgg ccgagctggc
    23461 cgagcgctac ggggaccggc tctgggtgcg cgctctcgac gtgacagacc cggtggcggt
    23521 gcgcaccgtc gtcgacgagg cgttcgccga cctgggacgc atcgacgtgg tcgtcaacaa
    23581 cgccgggtat gcgctgttcg gggccgctga ggagctcacg gacgagcaga tcgcccgcca
    23641 gatcgacacc aatctggtcg ggtcgatccg cgtcacccgc gcggtcatcc cgcacctgcg
    23701 ggcccagggc gccggccgga tcctccaact gtccagcatg ggcggccaga tcgcgtttcc
    23761 caacctgagc ctctaccacg cgaccaagtg gggcatcgaa ggcttcttcg agtccgtgat
    23821 cccggagatc g
//
