LOCUS       NZ_CP115450            22544 bp    DNA     linear   CON 17-DEC-2024
DEFINITION  Kitasatospora cathayae strain HUAS 3-15 chromosome, complete genome.
ACCESSION   NZ_CP115450
VERSION     NZ_CP115450.1
KEYWORDS    RefSeq.
SOURCE      Kitasatospora cathayae
  ORGANISM  Kitasatospora cathayae
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Kitasatospora.
REFERENCE   1  (bases 1 to 8860963)
  AUTHORS   Zheng,Y., Mo,P., Li,J., Zhou,Z., Huang,K., Luo,Y., Xie,P. and
            Wang,Y.
  TITLE     Kitasatospora cathayae sp. nov., a novel endophytic actinomycete
            isolated from the leaves of Cathaya argyrophylla
  JOURNAL   Int J Syst Evol Microbiol 74 (5) (2024)
   PUBMED   38809239
REFERENCE   2  (bases 1 to 8860963)
  AUTHORS   Mo,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-DEC-2022) College of Life and Environment Science,
            Hunan University of Arts and Science, No. 3150 Dongting Avenue,
            Changde, Hunan 415000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 8.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 155.15x
            Sequencing Technology             :: Oxford Nanopore PromethION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_027627435.1-RS_2024_12_16
            Annotation Date                   :: 12/16/2024 15:42:53
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,288
            CDSs (total)                      :: 8,175
            Genes (coding)                    :: 7,919
            CDSs (with protein)               :: 7,919
            Genes (RNA)                       :: 113
            rRNAs                             :: 11, 11, 11 (5S, 16S, 23S)
            complete rRNAs                    :: 11, 11, 11 (5S, 16S, 23S)
            tRNAs                             :: 77
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 256
            CDSs (without protein)            :: 256
            Pseudo Genes (ambiguous residues) :: 0 of 256
            Pseudo Genes (frameshifted)       :: 79 of 256
            Pseudo Genes (incomplete)         :: 220 of 256
            Pseudo Genes (internal stop)      :: 9 of 256
            Pseudo Genes (multiple problems)  :: 51 of 256
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:37:27
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2513166
            Orig. end                         :: 2535710
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP115450.1.
            Bacteria and source DNA available from Mo Ping.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22544
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="13"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22544
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22544
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12544](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12544)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     misc_feature    289..302
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.22"
                     /tool="antismash"
     misc_feature    289..303
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.76"
                     /tool="antismash"
     misc_feature    complement(290..303)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 18.06"
                     /tool="antismash"
     misc_feature    complement(293..306)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.66"
                     /tool="antismash"
     misc_feature    complement(312..325)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.16"
                     /tool="antismash"
     misc_feature    335..351
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 18.41"
                     /tool="antismash"
     misc_feature    complement(372..387)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.36"
                     /tool="antismash"
     regulatory      477..658
                     /bound_moiety="cyclic di-AMP"
                     /db_xref="RFAM:RF00379"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00379"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-AMP (ydaO/yuaA leader) riboswitch senses
                     the signaling molecule cyclic di-AMP; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(679..693)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     gene            968..1597
                     /locus_tag="O1G21_RS11115"
                     /old_locus_tag="O1G21_11115"
     CDS             968..1597
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012415.5"
                     /locus_tag="O1G21_RS11115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_11115"
                     /product="CAP domain-containing protein"
                     /protein_id="WP_270142919.1"
                     /transl_table=11
                     /translation="MSAHASTAPPPASPTVPASHTSWHPSASSSPSATSAPAPTATSTP
                     AAASTSAAAPSATPTASASPTAAGSDAVQQVLALINQARATHGLPAYTISAGLTSSAQA
                     HNQVMAAGCGLSHQCPNESGLGARESAAGVQWTSAGENIGDGGPVGTGAQDIAAEAVAL
                     TQDMLNEQPPNDGHRQNILSASFTHVGIAVHRDAGGTVWMSQDFSN"
     gene            complement(1895..2806)
                     /locus_tag="O1G21_RS11120"
                     /old_locus_tag="O1G21_11120"
     CDS             complement(1895..2806)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O1G21_RS11120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O1G21_11120"
                     /product="hypothetical protein"
                     /protein_id="WP_270142921.1"
                     /transl_table=11
                     /translation="MSGLQPALARSALTASTICWANWAAVPVAGVPATGALCVAGLVGL
                     GAVGTAGALLAGIAGAPLVGLACAFRTVGVALGMLVVGGGVDGFAVGVAAALAVAVAVT
                     AQLGVLVGWAEETNVTPGPGDNTPAAADGEAAPPPEDAAAASTPPVTATSPTTPATAAF
                     PRGRAALRRPRPRSCRAIPERPPPAASGSDATASITTVSNSLLMDPPSLLVDASFTPTP
                     RRPTNRASITKSEKRFSHSNSAPSARPLFRRQIRGDAPGQGDEERTAEWRRTVCPVTPR
                     GSGRADAVAVGGDLLAGRWLDG"
     gene            2808..3119
                     /locus_tag="O1G21_RS11125"
                     /old_locus_tag="O1G21_11125"
     CDS             2808..3119
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012415.5"
                     /locus_tag="O1G21_RS11125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_11125"
                     /product="CAP domain-containing protein"
                     /protein_id="WP_270142923.1"
                     /transl_table=11
                     /translation="MNAKLQAVAQEHSDDMAARNYYEHDTPEGVDPGTRITNAGYGWQN
                     WGENIYESPKDPATAMDGWMKSPAHRDNILDCVFTETGVGVNLSANGPWWTEDFARPQ"
     gene            3229..4752
                     /locus_tag="O1G21_RS11130"
                     /old_locus_tag="O1G21_11130"
     CDS             3229..4752
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606952.1"
                     /locus_tag="O1G21_RS11130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_11130"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_270142925.1"
                     /transl_table=11
                     /translation="MNSESGSKTVAAAQAGNAAARERLIADHLPLIYNIVGRALDGHAD
                     VDDVVQETMLRVVNSLDTLREPSSFRSWLVAVAMNEVRRRWTARKAAPVPGLQELTQVV
                     DPAADFVDLTILRLGLTGQRREVAEATRWLDERERDLLSLWWLETGGELTRAELATALN
                     LTPQHTAVRVQRMKEQLEIGRLVVRVLAADPPCAELSALTTAWDGKPAVLWRKRIARHA
                     RNCPHCAGHQHSLVPVEGLLAGLPLLLPPPHLAASPHLAAFATTAAQQALSRTARAATR
                     SAAPTRRLHPRHGRAVRTAKAATGVAAALTVLAGVQILRPGPDHTTPAPAVAVTPASPA
                     PAPTRPSPAPTVTEPQSPPATTTPPRQATPTPTPSTPTPQKTLEQQLVDLINIRRAKNG
                     CRPLRVNQRLHTAAQGHSDDMAVAGYFDHVDPRGNHADGRMTASGYQWSVWAENLDRDT
                     NSPNTVLKDWSDGAIHQQNMLDCQYTDAGVGTAPTPNGLLWTLDLGSPG"
     gene            complement(6555..9368)
                     /locus_tag="O1G21_RS11135"
                     /old_locus_tag="O1G21_11135"
     CDS             complement(6555..9368)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013124.5"
                     /locus_tag="O1G21_RS11135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_11135"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_270142927.1"
                     /transl_table=11
                     /translation="MTGMPSGPCYTVLGTVGVLRGEDPLPVGPPQQRALLAMLLLRRNT
                     TVGLDELIDGLWGEEPPRAAAGTVRLYVHRLRHALGPEIATHGKSYALRVAPGALDLDA
                     FEEQVARARARLTTDGPGAAAELLARALTWWRGVPLAGLPGPHARIHRERLSELRLAVL
                     LERIELDLQLGHHARLIPELTALCEEHPGDGRLDLLLDTARAHSGRNGTVRTVADSPPS
                     RRAPEKADGLAAALPPPAQLPYVPGDFTGRDEEMRTLVEALTPTSAEGLMIAAVSGMGG
                     VGKTTLAVHAAQRLRGHFPDGQLYANLRGMREDPADPAVVLAGFLRALGVADSVIPDDQ
                     EGRAALYRTRLAGRRILVVLDDARNYPQIEALLPGTPDCAVVVTSRTTIPELPAAPQLR
                     LDVLPTNKALALFRRIAGLERVAAEPEAAAALATRCGGLPLALRLAGSRLVARPAWSLS
                     DMVRLLDGSRWAMDAPAGGADGLATCFRHSYDLLGDEEARLFRLMAIPRQPTTDTEGAA
                     ALAGLPPAETGRCLERLADLGLLETPVPDTYRFHDLLREFAAARSEEQDRPEERAAALT
                     RLLDHFLTLACAAYARHRPGHPLVGLLLPAAPPGPSHTAPDDGPPRGLPEPSTLLAVAE
                     QVLEAAPAAIGPVANLVLALEPLLDRSFRWDCLVSPARRILDVAEEQGHLRAAGRIGHA
                     LGSALTMVGRFDEAEKTLHQAEQAMLMVGDEAVRTETLTRQALVWQCQGDWERAEAGFR
                     RAIAVGEDCGNAWGVGNSLLNSVSSLLRLGRLDDAATTCRAALESVRASKDHFGHAHAL
                     YQLGVVTRHLGEFEEAVARHRQSAELGARNGYPAFEVLNGVSETAALLAANRASDAAEC
                     GERAVAVARRLGWRAAEARALRLVGTAFEAAGERDLARQRLTEAVELLTSIGLPESAQA
                     KEILAGL"
     misc_feature    complement(9935..9949)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.56"
                     /tool="antismash"
     gene            complement(10001..12544)
                     /gene="lanKC"
                     /locus_tag="O1G21_RS11140"
                     /old_locus_tag="O1G21_11140"
     CDS             complement(10001..12544)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038151.1"
                     /locus_tag="O1G21_RS11140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_11140"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_270142928.1"
                     /sec_met_domain="micKC (E-value: 9.3e-220, bitscore: 730.7,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 0.00044, bitscore:
                     18.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEIHAYCLADPVFFEAPQRLRDGGSRWTPPPVGDGTRRETDEDV
                     WTRVSFGRPLPLQGWKIHVSAAVPAAQQVLDAAAAVCTARRAAFKYLRSAQLLSAFNSK
                     YSHRGSSGKFITVYPADDGELKALLDELTAALDGQQGPYILSDLRWSERSPVFVRYGAF
                     AARWAPVGGDAPVPAIARPDGTPVHDPRTAAFTPPDWAPVPDFVRERIDRFAEISHVDL
                     PYEIVRPLHFSNGGGVYLAKDRAGGDLVVLKEARPLAGLDAEGLDAVARLQREHRMLTA
                     LAGTGLVPRVLGYRTYWEHHFLIQEYIDGEPLAKAGVLRQPLVRPDADPAAYEEYTRWA
                     LDVLDRVAAATAVVHRAGIVFGDLHPNNVIVRPDGSVTFVDLEAAHRVGEPRTGLLGAP
                     GFAAPAHVTGTDVDAYGLAALRLGQFVPLGALAGLDPAKPAQLARWAHERFPLPVGHAR
                     DAAAAMAAIAGTTVPAAVRAAGPADADGEENRARLVAALVASATPERTDRLFPNAPEGS
                     QEGGGTSLSHGAAGVLYALHATGHAVDPAWTDWLTAATLRNLATAPVGLFNGSCGAATV
                     LDLLGRRDEAADIMGRILDRTVEPTGLGLLTGLPGTGLTVLGFHRRSGDGGHLDHAARI
                     AARIEAALARPGGARPGAGLTTGAAGSALFLVRLHERTGEPGYLDLAEKALRLDLAQCE
                     DVGGSLQVNDGWRSVIYLGTGTTGIGLALSAYLEHRADPGFTDALRAIRKAAHCGFTVF
                     PGLLNGRAGLLYFLAAAGQDGADDTALQGHLRELWRHSVPHGEGLGFPGDHLVRLSMDL
                     ATGSAGVLLAMDAAHRRTDLLLPLLGGTAPASAAS"
     misc_feature    complement(12374..12376)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            12909..13337
                     /locus_tag="O1G21_RS11145"
                     /old_locus_tag="O1G21_11145"
     CDS             12909..13337
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025442.5"
                     /locus_tag="O1G21_RS11145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_11145"
                     /product="DUF4258 domain-containing protein"
                     /protein_id="WP_270142930.1"
                     /transl_table=11
                     /translation="MNSSKRLRLMAVGAVTAAVAAVAGPALAVPAFAAQPTGQVALVNP
                     PTRGGHEPTFADCGSDHAPGSFDRISQHAEQRMKDRDVSEDELRNAVRINAKDAWCQTN
                     GNWHYSLGMAGGQLEVIIGANRGQWVVVTVFWKGEPNI"
     gene            13350..14867
                     /locus_tag="O1G21_RS11150"
                     /old_locus_tag="O1G21_11150"
     CDS             13350..14867
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015649.5"
                     /locus_tag="O1G21_RS11150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_11150"
                     /product="AfsR/SARP family transcriptional regulator"
                     /protein_id="WP_270142932.1"
                     /transl_table=11
                     /translation="MKPGFRLLGATGVRLGDQPVRPGPPQQQALLAMLLLRGGRTVTAR
                     ELVAGVWGQDAPARALRSVRTYAWALRALLEPDRSPREPSTLLRSDGDGYALRVPDDAL
                     DVTVFERLLGVAREARAHGDLASAHRSLGEALALWGGEPFTGVPGPHAERERTRLVRLR
                     LEAQEQYFDCALDLGMHGRVLPELSALAREHPLDEHLQGLLMRALDSCGRQAEALKVYG
                     DTRRLLAAELGVPPGRELTRVRDGLATDGRAASSGPPATPRSPAAGGGPTGREGATVEL
                     ERTLTDPRRHRVPVAVITGAGGTGKTTLATRVAHRVAAHFPDGRLSVDLRGSHPTRLPE
                     GDVLARLLRSLGVPPEDVPVETEQRAALYRSMLGGRRILIILDDAADAAQVAPLLPGSP
                     GCAAVVTARSRAFVLPGATQLALPARPGPATDRRRQLPPRLALALDSLAGSGAPTLPIE
                     LVGRLLGTDREEAEHIAESLVDAGLLDSPGYRMYRIACPDAPSPDGS"
     gene            complement(16088..16435)
                     /locus_tag="O1G21_RS11155"
                     /old_locus_tag="O1G21_11155"
     CDS             complement(16088..16435)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O1G21_RS11155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O1G21_11155"
                     /product="hypothetical protein"
                     /protein_id="WP_270142934.1"
                     /transl_table=11
                     /translation="MGSLIEELEAREAAARVRVEEFSAELASVSAKLELARERPERLRI
                     ARETVAEVLAEMTSEMPAVTINAGQPPAGERVVSAYAGAERQVIGALTVPNDPVEGSLA
                     DEVRKLVHVLA"
     misc_feature    16455..16473
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.42"
                     /tool="antismash"
     gene            complement(16988..17902)
                     /locus_tag="O1G21_RS11160"
                     /old_locus_tag="O1G21_11160"
     CDS             complement(16988..17902)
                     /GO_function="GO:0030598 - rRNA N-glycosylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012388.5"
                     /locus_tag="O1G21_RS11160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_11160"
                     /product="ribosome-inactivating family protein"
                     /protein_id="WP_270142935.1"
                     /transl_table=11
                     /translation="MLGRLRRTLRQAVGGLVLALAVTAGLLCPAGTASASTGDGSVSHV
                     WLNLGHAPSPNLRISYSTFLASLRAAVGNSLQGVEVAQAASQNEGVVRVSLSAVDDHGT
                     ERAVDLWINPDNLYLVGYSPQATPGVSYIFNDIHASAAIPTARQNLPFGGNYNSLVGAA
                     HRDRSNTPISFSSIRQAVLDLANQRSAGSNQQTTARALLLLIQFTSEAARFNDLEGVFR
                     NVLADWGNSGSGIPSWLQQMENNWGTLSNFFWNDLGFGNNPHPAPLTIGGIRINNASDV
                     RRYVRTVLTPVVGTSFNPGHQEL"
     misc_feature    complement(17904..17917)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.36"
                     /tool="antismash"
     misc_feature    complement(18076..18089)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.27"
                     /tool="antismash"
     misc_feature    complement(18256..18269)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.53"
                     /tool="antismash"
     gene            18425..18997
                     /locus_tag="O1G21_RS11165"
                     /old_locus_tag="O1G21_11165"
     CDS             18425..18997
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1238: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003962957.1"
                     /locus_tag="O1G21_RS11165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_11165"
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="WP_270150908.1"
                     /transl_table=11
                     /translation="MTAAGRLRRESVRMQAAELFEQDVKPPEVARRLRVSPKSAYQWHQ
                     LWCEGGVQALASRGPSGSRCRLSPRCLEKLAAYLEQGPAAHGWVEDQVWTAARVATLIG
                     RKFHVSYSVSGATRLMHRLGFSPQVPARRVAERDEQAVTAWKEATWAEVKERGRPAGAT
                     SASRTRQDSPADRPKDAPGADEAARRL"
     gene            18913..19479
                     /locus_tag="O1G21_RS11170"
                     /old_locus_tag="O1G21_11170"
     CDS             18913..19479
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1238: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015655131.1"
                     /locus_tag="O1G21_RS11170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_11170"
                     /product="transposase"
                     /protein_id="WP_270150910.1"
                     /transl_table=11
                     /translation="MCFEDEAGFTRRPPKGRTWGRRGRTPVVTVSGRRSGRLSVAGVIA
                     MRPGSRTRLCHRLHTHPAGRGKRRSMGERDFIALIDGVHQLVKAPIVLVWDRLNTHISH
                     AMRDLIAERAWLTVFLLPAYSPDLNPVEWVWAHVERSLANLAVVALDRLEALVRNRLKR
                     LQYRPDTLDGFIAGTGLTLDTPASP"
     gene            complement(19840..22542)
                     /locus_tag="O1G21_RS11175"
                     /old_locus_tag="O1G21_11175"
     CDS             complement(19840..22542)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669386.1"
                     /locus_tag="O1G21_RS11175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1G21_11175"
                     /product="glycosyl hydrolase"
                     /protein_id="WP_270142936.1"
                     /transl_table=11
                     /translation="MPNRQRRRLLLSAVTLTALGLTATQAMAAPVAQPGTQPNPVQRLT
                     EAGQRHAQKVTGKPAGGHTFSAKAETGGDGGSDEAENSAEGTAQYTEARTAPGVVAPGA
                     YGAAWAQLQSLPHTGGSWDHVTNKPYNGDDPRYRDVNSNSSGGAGFVTGRITGIAADSD
                     GYVYAGGANGGVFRSRTGGGHWEPIADKLPTLSTGTLNLDGGGRLWYATGESNTGATSY
                     VGTGVYVLSDPKHGKFQPGNRVGGAELESTTIHQLRFAGDKVWAATNRGVWSHSTTDLS
                     GPWTMEFAPNPDYLPGGAKASDPSAPYKNIANDIAIDSKDPSKVILAVGWRGGDTYNGF
                     YSKAADGSWQRVASLGDLPTDAANVGNVTFARSADGSRYYAIDQSPDVMAHNPDTGLKG
                     IYVSKSGSPAGPWALIADKDKLKGSGSALQDAGYQPGIQSWYNQFLQVDPANPDHVWAG
                     LEEVFETTDGGAKWATVAPYWNNPFPCWSIDPAKQTGDCSPTTHSDQHAVAIGSYQGKT
                     SVYVGNDGGIYTRPVNGQLDAGGHAKDWKSLNDGTIDTLQYYSVGIGKDLADRSGRGVI
                     VSGGLQDNGESILRAHDKVMGSNFGGDGGDTLVDPANGCNIGEEYVYLDMWVTQNCAVN
                     DGSWTRDPSKATSYEVAPPDKATSAARFIAPITTDPKDTNTWIAGGQHVWVQHKGYAIR
                     SGSEWTSAYDLGAGHVATAVATVNGTVYAGWCGPCNNQGFTRGIAVGNTDGTGWHQLNL
                     PVDGTLPNRYVSSFAVDENDAQHVFVAFSGFSRSWTEGPGAGIGHLFETRDGGASWTDV
                     SANLPDVPATSIKLLPNGGLALGTDLAAFYRAPGATDFRVLGRNLPTTSVQQLKIGPDG
                     KLYAATFGRGIWSFDLRRLGHGRYDETDD"
ORIGIN
        1 cctttgggca cctggtggtt gaagattcgg acagtcatcg cccgcacctc ctccacgcgg
       61 atccgcggcg ggaacgcttc aaggccgccg gacatattct tcgactcggg cccgacctcc
      121 gactggcttc cgcccctgat tcccgcccgc tcacgggccg ggccgcgggg tcgctggaca
      181 cccggcggcc ccgctgccgt gcccgaccag gcggcgactg tcgcgcacac ccgtgagagc
      241 cactacctcc gcctatgact ccgtagccat attgtcatag ttagggcgat ttttttgata
      301 tatgaactac ttgattatct ttagatctat ttacttgcaa tcttttgacc ggatgtcaac
      361 tgccgggcct gtgtgacgtg aatgacaatg tcttgtgatc accgattcgg cttgcctagc
      421 gtgcaggcgt tcgcatctgc ggaccctgtc gtcgggacgc cgagtcctgc ccaccggccg
      481 gcaggacgtc gagctctgcg tcgggcagga gcgggggacc caggaagtcg ccgtgtccgc
      541 tcggcccgtc caacgggcct gccgggacgc ggctaggggt gaagccgctc atacgcggcc
      601 gggctacctc gcggcccgaa cccgacagct cacctcgcag gcgtcgccga ggggtccccc
      661 catgctgtct tcccgccgtg gccgacaccg tcgatcgcgc cgcagccgcg tcccgcgcct
      721 ggccaccacc gccggattcg tcggcgtcgg cctggctatg ccgctgatca ccgccagcac
      781 aagctccgcc gcctccgtcc gccaccccca ccatcacccc cacagtcccg tggcgtccgc
      841 cgccgttccg gcgcagcgcc acgacgccta cgctcccggc agcgcccctg gccgcgggag
      901 ctccccgtgg gccttcgccg cgcccaccgc ctcgggcgta ccgacggcct ctgcagcgcc
      961 gaccgccgtg tccgcccatg cctccaccgc gccgcccccg gcttcgccta cggtcccggc
     1021 ctcccacacc tcctggcacc cgtcggcatc ctcgtcgccg tcggccacat cggcccccgc
     1081 ccccaccgcg acgtcgacgc ccgctgctgc ctccacctcc gcggccgctc cgtcggccac
     1141 gccgacggcc tccgcgagcc cgaccgcggc cggctcggac gccgtccaac aagtactcgc
     1201 tctgatcaac caggcccgag ccacccatgg cctgccggcg tacaccatca gcgcgggcct
     1261 gaccagcagc gcccaagccc acaaccaggt gatggccgcc ggctgcggcc tgtcccacca
     1321 gtgcccgaac gagagcggac tgggtgcccg ggagagcgcc gcaggcgtcc agtggacctc
     1381 cgccggggag aacataggcg acggcggccc ggtcggcacc ggggcgcagg acatcgccgc
     1441 cgaggcggtg gccctgaccc aggacatgct gaacgagcag ccgccgaacg acggccaccg
     1501 gcagaacatc ctgagcgcct cgttcactca cgtcggcatc gctgtccacc gggacgccgg
     1561 cggtaccgtc tggatgtctc aggacttctc caactgagtc cgggccgacc gcacaccgtc
     1621 ggggcggccg catcacgcgg ccgcccccga cgaccaggta ccttccacgt gcgagctgtg
     1681 ggcgcgggcg gtggccggca ccgacagcgt gctgccgggc gttgactcgc aaccagcagg
     1741 tcgttctgac cgtgggcagc gagcgctggt ccgccgacac tgcgtcttgt cccgctgcgc
     1801 aacgcggccg ccaccgggac cggccgtgtc ggcgcaacca cggccgcgaa gtccatctgc
     1861 ggggccgagg acccggttca gccggtccag cagctcaccc gtcgagccac cgtcccgcca
     1921 ggagatcccc acccaccgcc acggcgtccg cccgaccact gccacgaggt gtgaccgggc
     1981 agaccgtgcg cctccattcc gcggtccgct cctcgtcgcc ctggccgggt gcgtcaccgc
     2041 ggatctgccg gcgaaacagg ggcctggcgg acggggcgga gttggagtgc gaaaaccgct
     2101 tttcggattt tgttatcgag gcccggttcg tcggtctcct gggggtcggc gtgaacgacg
     2161 cgtcgacgag gagcgaaggc ggatccatga gcagtgagtt cgagaccgtg gtgatcgatg
     2221 cggtggcgtc cgagccggac gctgcgggag gtggccgctc ggggatggcg cggcacgagc
     2281 gcgggcgtgg tcggcggagg gctgcgcggc cacgtgggaa ggcggcggtt gccggagtgg
     2341 tggggctggt cgcggtcacg ggtggggtgc tcgctgccgc ggcgtcctcc gggggtggag
     2401 ccgcttcgcc gtccgccgcg gccggcgtgt tgtcgccggg gcccggtgtc acgttcgttt
     2461 cctcggccca gccgaccagt acgccgagct gggcggtcac tgcgaccgcg accgcgagtg
     2521 ccgcggcgac cccgacagcg aatccgtcga cgcccccgcc gacgaccagc atgccgagcg
     2581 ctacgcctac cgttcggaag gcgcaggcga ggccgacgag cggtgctccg gcgatcccgg
     2641 cgagcagtgc cccggcggtc ccgacggccc ccaagcccac cagtcccgcc acgcacagcg
     2701 cgccggtcgc gggaacaccg gcgaccggta ccgctgccca gttcgcccag cagatcgtcg
     2761 acgcggtcaa cgccgaacgc gccaaggccg gctgcaagcc gctcaccgtg aacgcgaagc
     2821 tgcaggccgt ggcgcaggag cactccgacg acatggccgc ccgcaactac tacgagcacg
     2881 acaccccgga aggcgtcgac cccggcaccc ggataaccaa cgccgggtac ggctggcaga
     2941 actggggcga gaacatctac gagagcccga aggaccccgc cacggccatg gacggctgga
     3001 tgaagagtcc cgcacaccgc gacaacatcc tggactgcgt cttcacggag accggtgtcg
     3061 gcgtgaacct cagcgccaac gggccctggt ggaccgagga cttcgcccgt ccccagtgag
     3121 cggacggtga gccccaccgc cggctcgatt tctgtcattc ccaccctctc gccggggtct
     3181 cacatggcgc gggaggaacg atcacccagt tgaggacgac ggacgctgat gaacagtgaa
     3241 agcggcagca agacggtcgc cgcggcgcag gcagggaacg cggcggcccg ggaacggttg
     3301 atagccgacc accttccgct gatctacaac atcgtcggcc gcgcgctgga cggccatgcc
     3361 gacgtggacg acgtggtgca ggaaaccatg ctccgcgtcg tcaactccct ggacacgctg
     3421 cgcgagccgt cctccttccg gtcctggctg gtggcggtgg cgatgaacga ggtccgtcgg
     3481 cgctggacgg cacggaaggc ggcacccgtg ccgggcctgc aggaactgac gcaggtcgtc
     3541 gatccagccg ccgacttcgt ggacctgacc atcctgcggc tcggcctgac gggccagcgc
     3601 agggaggtcg ccgaagccac ccgctggctg gacgagcgcg agcgcgacct actctccctc
     3661 tggtggctgg agaccggcgg tgagctcacc cgggccgaac tggcgacagc cctcaacctc
     3721 acaccgcagc acaccgccgt acgggtccag cggatgaagg aacaactgga gatcggccgc
     3781 ctggtggtgc gagtactcgc cgccgacccg ccgtgcgccg aactgtcggc gctcaccacg
     3841 gcctgggacg ggaagccggc cgtactgtgg cgcaaacgca tcgccaggca cgcccggaac
     3901 tgtccgcact gcgcggggca ccagcacagt ctggtaccgg tcgagggact gctcgccggc
     3961 ctcccgctgc tgctcccgcc accgcacctg gccgcctcac cgcacctggc cgcgttcgcc
     4021 accacggccg cgcagcaggc actctcccgc acagcgcgcg cggcgacacg ctcggccgcc
     4081 ccgacacgca ggctccaccc gcgccatggg cgggcggtca ggactgccaa ggcagccacg
     4141 ggagtcgcgg ccgccttgac cgtcctcgcc ggagtgcaga tcctccgacc cggccccgac
     4201 cacaccacgc ccgctcccgc ggtcgcggtc acgcccgcat ccccggcgcc ggcccccacc
     4261 aggccatctc ccgcaccaac cgtcaccgaa ccccagtccc cgcccgccac caccactcct
     4321 cctcgccagg ccacgcccac cccgaccccc tccacgccca caccccagaa gacactcgaa
     4381 cagcaactcg tcgacctgat caacatccga cgggcgaaga acggctgcag gccgctgcgc
     4441 gtcaaccagc gcctgcacac ggccgcccaa gggcattccg acgacatggc cgtcgccggc
     4501 tacttcgacc acgtcgaccc gcgcggcaac cacgccgacg gccgcatgac cgcctccggc
     4561 taccagtgga gtgtgtgggc cgagaacctc gaccgggaca cgaactcgcc gaacaccgtg
     4621 ctgaaggact ggtcggacgg cgcgatccac cagcagaaca tgctcgactg ccagtacacc
     4681 gacgccggcg tcggcaccgc ccccaccccg aacggcctgc tctggaccct cgacctgggc
     4741 agcccaggct gacagcccta ccagtccgcc attcgcatgc cactctcagc gggccaggaa
     4801 cgtccgtcga gccgtcagca tgcgcgaaga cgcactcgta cggggtgccg cggaactcag
     4861 tccacaactc gcgcccggac gcccggtccg aggcgagcag ttggaagaag tcgttgcggc
     4921 cgccgcgcct ggccgtgtgc cagtcaacag cttgagtccg accgctcgga cgtcgctctt
     4981 ccggtcccgg tccgggacgt cgtggtaggc gaggcgcagg agctcggcgc agctcgcctc
     5041 catcggcgcg ggagatggcg aacgattcct ggcgctacgt caggaattct cgcctgcccc
     5101 ctacgtcgcc tacatcttca acgaaggcgg ctgcggctgc ggctgcctca tcgtcgctcg
     5161 acccacccgg ccctcgggca gcaactggac ctgtcggcgc gcacttgacc gacggcagat
     5221 acgtcaagtg cgaagcctcc ggccagaagg ttcgatcacg gcgagcaacc atcgcaccca
     5281 tagcagtgat cgataaatcc gacatagaac ccgaagcggc gcatatgatc gccagctaac
     5341 ggctcgcgca gcccgcagcg ccaccaatga accgtggaaa ccgtgagacg aatgtgagag
     5401 gcaggctcca caacacacca aaggccgctc cctcacgaag gaggaagcgg cctctgacct
     5461 gcgacaacgg ggcgaacccc agtcgggacg acaggatttg aacctgcgac cccttgaccc
     5521 ccagggggtt caactagtgt cgacagccga ggcctcacgg cctcggcttt cttgttgctc
     5581 aagtgaactg aaaaccaggg aagttgaaac tcgtcatgga gatccacgat cggcagagcc
     5641 agaacccgtc ggatgcccag gctggtttca agttcgtaca tagatgcccg ctatcgccca
     5701 cgggcgctca tgggcgtcac caggcacagt cccaaactgg tccccaaatg gtccccaggc
     5761 ccccgacccg cctttgtcac cgcgagtgac agtagtctgt cgacccttca gcaggccccc
     5821 tctgccgacc gccgcagccc gtcctgcatt gcccctggcc agacgaggcg gtccggtcgg
     5881 atcagggtcg actacccact ggattcggat agtgatcttt cggacggcgt gtcgtcttga
     5941 gcgtgtcctc gccatgcggt tctgacgtgc ttcgcgcacc gcccgacgcg ctctgccgcc
     6001 acacccgaca cagcagccac tcttgcctca gatttaccac ccagtccggg agaaggggaa
     6061 gttcgtggaa cagcgtgcgc agcgaggcag ggtgtatcgg cggtgtgagt gccgggagga
     6121 gggcgggcgg cagttgggtg cgtggtgtgt gcggttgttg gaggaggccg aggtcgcggc
     6181 ctatctcgcc gggatccggc cggagttgct gacgccggcc cgtccggtcg cggccagggg
     6241 tcacgccgcc cgcgctggaa gttctccgcc tgctgcgcgg cttcggccgc agccgccgcg
     6301 agcgcgctgc cgcccggggg ctgacgaacg cgtcgatcgg tctgctgccg ccctgggccc
     6361 gggccgaact cgccctccgg cggacctcgt tggtccgtat ggtctgggac cgcccgccgg
     6421 cgcgggccgg cggccgggtc atggtccggg cctgcggtcc ctcaccgatc cgcgccgcca
     6481 cccacgcccg ggccgccgcc gcgccccggg cggcggggac ctgacgcacc cccggggccc
     6541 gcgcggccgc gccgtcacag tccggccagg atctccttgg cctgggcgga ctccggcagg
     6601 ccgatcgagg tcaggagttc caccgcctcc gtcagccgtt gccgcgccag gtcccgttca
     6661 cctgccgcct cgaacgcggt gcccaccagg cggagcgcac gggcctccgc tgcccgccaa
     6721 ccgagccggc gggcaacggc cacggctcgc tcgccgcact ccgcggcgtc cgaggcccgg
     6781 ttcgcggcca ggagggcggc ggtctccgac accccgttca ggacctcgaa cgcggggtac
     6841 ccgttgcggg ccccgagttc cgcactctgc cggtgccggg cgacggcctc ctcgaactcc
     6901 ccgaggtgcc gggtcaccac tcccagctgg tacagggcgt gggcgtgccc gaagtggtcc
     6961 ttcgacgccc ggacgctctc cagggcggcc cgacaggtcg tcgccgcgtc gtccagccgg
     7021 cccagccgca gcagcgaact aacgctgttc agcagcgagt tgccgactcc ccaggcgttg
     7081 ccgcagtcct cgccgacggc gatcgcccgg cggaatccgg cctcggcccg ttcccagtcg
     7141 ccctggcact gccacaccag ggcctgccgg gtgagcgtct cggtgcgcac ggcctcgtcc
     7201 ccgaccatga gcatcgcctg ttccgcctgg tggagcgtct tctcggcctc gtcgaagcgg
     7261 cccaccatgg tcagggcgct tccgagcgcg tgcccgatgc gtcccgccgc ccgcaggtgc
     7321 ccctgctcct cggcgacgtc caggatcctg cgggccgggg agaccaggca gtcccaccgg
     7381 aacgagcggt ccaggagcgg ttcgagggcg agcaccagat tggcgaccgg accgatggcc
     7441 gcgggcgcgg cttccagcac ctgttcggcg acggcgagca gggtcgaggg ctcgggcagg
     7501 ccccggggcg gtccgtcgtc gggggcggtg tgcgacgggc cgggcggcgc ggcgggcagc
     7561 agcaggccga cgagcggatg gcccggacgg tgccgggcgt aggcggcgca ggccagggtc
     7621 aggaagtggt ccagcagccg ggtgagggcc gccgcccgtt cctcgggccg gtcctgctcc
     7681 tccgaccgcg ccgccgcgaa ctcccggagc aggtcgtgga agcggtaggt atcggggacc
     7741 ggtgtttcga gcagtccgag gtcggccagc cgctccagac atcgcccggt ctcggccggc
     7801 ggcagcccgg cgagcgctgc cgcgccttcg gtgtcggtgg tcggctgccg cggtatcgcc
     7861 atgagccgga acagccgggc ctcctcgtcg ccgagcaggt cgtagctgtg ccggaagcag
     7921 gtggccagcc cgtccgcgcc gccggcgggc gcgtccatgg cccagcggga cccgtcgagc
     7981 aggcggacca tgtcggacag cgaccacgcg ggccgggcca ccaggcggga tccggcgagc
     8041 cgcagcgcca gcggcagccc tccgcaccgg gtggccagtg ccgcggccgc ttccggctcc
     8101 gccgcgacac gttcgagtcc ggcgatccgg cggaacaggg ccagcgcctt gttggtgggc
     8161 agcacgtcga gccgcagctg cggtgcggcc ggcagttccg ggatcgtggt gcggctggtc
     8221 accaccaccg cacagtccgg tgtgcccggc agcagcgcct cgatctgggg gtagttccgg
     8281 gcgtcgtcga gcaccaccag gatccggcgc cccgccagcc tggtccgata gagcgccgca
     8341 cgcccctcct ggtcgtcggg gatcacggag tccgccacac cgagcgcccg aaggaagccg
     8401 gccaggacca cggcggggtc ggccgggtcc tcccgcatgc cccggaggtt ggcgtagagc
     8461 tgtccgtcgg gaaagtgccc gcgcagccgc tgggccgcgt ggacggcgag cgtggtcttt
     8521 ccgacgcctc ccatgccgct gacggcagcg atcatcaggc cctcggcgct ggtcggcgtc
     8581 agcgcctcca ccagcgtccg catctcctcg tcgcgtccgg tgaagtcacc tggcacgtag
     8641 ggaagttgcg ccggaggtgg cagtgccgca gcgagcccgt cagccttctc cggtgctcgc
     8701 cgcgaaggcg gggagtcggc cacggtccgt acggttccgt tccggccgct gtgcgcccgc
     8761 gcggtgtcga gcagcaggtc cagccggccg tcgccagggt gttcctcgca cagcgcggtc
     8821 agctcgggga tcagccgggc gtggtgcccc agttgcaggt cgagttcgat ccgctccagc
     8881 agaacggcca ggcgcagctc ggacaggcgc tcgcggtgga tgcgggcgtg cgggcccggc
     8941 agccccgcca gggggacgcc ccgccaccag gtcagcgcgc gtgccagcag ttctgccgcg
     9001 gcgcccggcc cgtcggtggt gagccgggcg cgggcccggg ccacctgctc ctcgaacgcg
     9061 tcgaggtcca gggcgccggg tgcgacgcgc aaggcgtagg actttccatg ggtggcgatc
     9121 tcgggcccga gcgcgtggcg cagccggtgg acatagagcc gtaccgtgcc cgccgcggcg
     9181 cggggcggct cctcgcccca caggccgtcg atcagttcgt cgagccccac cgtcgtgttg
     9241 cgccgcagca gcaacatggc cagcagcgcg cgctgttggg ggggcccgac gggaagcgga
     9301 tcctcacccc gcagcacccc gaccgttccc agcacggtgt agcacggccc ggacggcatg
     9361 ccggtcatcg gcgtcgactc cctcgttccc ccgtacccgg cgatggcgga cggccgggac
     9421 ggaaacctta acaagtcgcc gttccggatc aggaccgtgt gcgatcggga gctgacggaa
     9481 agtcgggatt ccggagggag cgtgcggtgc cccaagtcgg cctgccggtg gccggaatgg
     9541 gaagaacagg ccgcggggct ggaccccgcg gcctgtggta cttcgcgacc gatctcaccg
     9601 tctccggtga gtacggtgcg tcagcccacg aagctggtgt tgtggcactg gaagctggcg
     9661 gtgctcgcga gcagcacctc gttgtcctcg tgggcgtcga gctgctggag gctgaggatc
     9721 gacatgggta caactccttc tgttggtcgg ggatttcgcc gggcctggtg aggccgacgg
     9781 actcctgggg gccggcggtc cgcggtgtcg gaccgccggc gaggggtgcg caggtcaccc
     9841 gctcagatgg tggtgccgtg gcacgcccag ctgagggcgc tggccaggaa cggctcgttg
     9901 tcctcggaac cctggagctg ctggaggttg aggatggaca tggtggtcac ctccttcggg
     9961 tgggtggggg ttgcgccgcg ccggtcgagg cgcagcgggc tcaggaggcg gcggaggccg
    10021 gggccgttcc gccgagcagg ggaagaagaa ggtcggtgcg gcggtgggcg gcgtccatcg
    10081 ccaggagcac gccggccgac ccggtggcga ggtccatcga cagccggacc aggtggtccc
    10141 cggggaaacc gaggccttcg ccgtggggga cggagtgccg ccacagctcg cgcaggtggc
    10201 cctggagcgc ggtgtcgtcc gcgccgtcct gcccggcggc cgccaggaag tacagcaggc
    10261 cggcacggcc gttgaggagg ccggggaaga cggtgaaccc gcagtgcgcc gccttgcgga
    10321 tcgcccggag ggcatcggtg aagccgggat cggcgcggtg ctcgaggtag gcggagaggg
    10381 cgagcccgat gccggtggtg ccggtgccga ggtagatgac ggaccgccag ccgtcgttga
    10441 cctggaggga tccgccgacg tcctcgcact gcgcgaggtc gaggcgcagc gccttctcgg
    10501 ccaggtcgag gtagcccggt tcgccggtgc gttcgtgcag gcggacgagg aacagggcgg
    10561 atccggccgc cccggtcgtg aggcccgcgc ccgggcgggc gccgcccggg cgggcgaggg
    10621 cggcttcgat ccgggcggcg atccgggcgg cgtggtcgag gtggccgccg tcaccgctgc
    10681 ggcggtggaa cccgaggacg gtcaggccgg tgccgggcag gccggtcagc aggccgaggc
    10741 cggtcggctc gacggtgcgg tcgaggatcc ggcccatgat gtccgcggct tcgtcgcgcc
    10801 gtccgaggag gtccaggacg gtggccgccc cacaggagcc gttgaacagg ccgaccggtg
    10861 cggtggcgag gttgcgcagg gtcgcggccg tgagccagtc ggtccaggcc gggtcgacgg
    10921 cgtggcccgt cgcgtggagg gcgtacagga cgcccgcggc tccgtgggac aggctggtgc
    10981 cgccgccctc ctgcgacccc tcgggggcgt tggggaagag ccggtcggtc cgctccgggg
    11041 tggccgaggc gacgagcgcc gcgacgagcc gtgcccggtt ctcctccccg tccgcgtcgg
    11101 cgggaccggc cgcgcggacc gctgccggta cggtggtccc ggcgatggcc gccatggccg
    11161 ccgcggcgtc ccgggcgtgg ccgacgggca acgggaagcg ttcgtgagcc caccgtgcga
    11221 gctgggcggg cttggccgga tcgaggcctg ccagcgctcc cagcgggacg aactgcccca
    11281 accgcagggc ggccagtccg taggcgtcga cgtcggtgcc ggtgacatgg gcgggtgcgg
    11341 cgaacccggg tgcgcccagc aggcccgtgc gcggctcgcc cacccggtgg gcggcctcca
    11401 ggtcgacgaa ggtgacggag ccgtccgggc gcacgatgac gttgttgggg tggaggtcgc
    11461 cgaagacgat cccggcccgg tggacgacgg ccgtcgccgc ggcgaccctg tcgaggacgt
    11521 ccagcgccca gcgggtgtac tcctcgtacg cggccggatc ggcgtccgga cgcaccagcg
    11581 gctggcgcag caccccggcc ttcgccagcg gctcgccgtc gatgtactcc tggatcagga
    11641 agtggtgctc ccagtaggtc cggtagccca gcacgcgcgg tacgaggccg gtgccggcca
    11701 gcgcggtgag catccggtgt tcccgctgga gccgggccac cgcgtcgagc ccctccgcgt
    11761 cgagtccggc cagcggccgg gcctccttca ggacgaccag gtcgccgccg gcccggtcct
    11821 tggccaggta gaccccgcct ccgttggaga agtgcagcgg ccggacgatc tcgtacggca
    11881 ggtccacgtg gctgatctcg gcgaaccggt cgatgcgttc ccggacgaag tcgggcaccg
    11941 gtgcccagtc gggcggggtg aacgcggcgg tgcgcggatc gtgcaccggc gtgccgtccg
    12001 gccgggcgat ggccggtacc ggggcgtcgc ccccgacggg ggcccaccgc gcggcgaagg
    12061 ccccgtagcg cacgaacacc gggctgcgct cgctccagcg caggtcggac aggatgtagg
    12121 ggccctgctg tccgtccagc gcggccgtga gctcgtccag cagggccttc aactcgccgt
    12181 cgtccgcggg gtagacggtg atgaacttcc ccgaggaacc ccggtgggag tacttggaat
    12241 tgaacgccga cagcagctgg gcgctgcgca ggtacttgaa ggcggcgcgg cgggcggtgc
    12301 agacggcggc ggccgcgtcc aggacctgct gggcggcggg cacagcggcc gacacgtgaa
    12361 tcttccaccc ctgtaagggc aacggccggc cgaaggagac ccgtgtccac acgtcctcgt
    12421 cggtctcccg gcgggtgcca tcgccgaccg gcggcggtgt ccagcgggag cccccgtccc
    12481 ggaggcgctg cggtgcctcg aagaacaccg ggtcggcgag gcagtaggcg tgtatctctt
    12541 ccatgttcat cgtcttcccc ctccccggga gtgcggttcg gccgcaggtg cggtccggcg
    12601 tggagcgcgg tccggccgca ggtgcggtcg ggcctgtagc gcggtccggc cgcaggtgcg
    12661 gtcgggcctg tagcgcggtc cggcctggag tgcgtagggc cgccgtcggc ggtccccgga
    12721 ggaggaccac cggagcgccg ggctcggaca ccaccttgcg acggcccgat ccatcgccga
    12781 tgagcgcccg gttagcgtcg gccgcggacc ccgttaaccg cccgctgatc gcccgtggac
    12841 cggcgccggt caccttgatc acggcggccg atgggccgtg catgcaccga acggacagtg
    12901 gagtcatcgt gaacagttcg aagcgtcttc gcctcatggc cgtcggcgcc gtcaccgccg
    12961 cggttgcggc ggtcgccggg ccggcactgg ccgtaccggc gttcgcggct cagcccaccg
    13021 ggcaggtcgc gctcgtgaac ccgcccaccc ggggcgggca cgagcccacc ttcgccgact
    13081 gcggctccga ccacgctccc ggctcgttcg accggatcag ccagcacgcc gagcagcgga
    13141 tgaaggatcg cgacgtgagc gaggacgagc tccggaacgc cgtccgcatc aacgccaagg
    13201 acgcctggtg ccagacgaat ggcaactggc actactcgct cggcatggcc ggtggtcaac
    13261 tggaggtcat catcggcgcc aacaggggac agtgggtcgt cgtcaccgtc ttctggaagg
    13321 gtgagccgaa catctagcga cggggagcga tgaagcccgg attccggctg ctgggggcca
    13381 cgggcgtacg gctgggagac cagccggtac gcccgggccc gccgcagcaa caggcactgc
    13441 tcgccatgct gctgctgcgc ggcggacgga ccgtcaccgc gcgcgaactg gtcgccggcg
    13501 tctgggggca ggacgccccg gcccgtgcgc tgcgctccgt acgcacctac gcctgggcgc
    13561 tgcgcgcact gctggagccg gaccgttcac cgcgggagcc gagcaccctc ctgcgctcgg
    13621 acggggacgg ctacgcactc cgggtgccgg acgacgcgct ggacgtcacg gtcttcgaac
    13681 ggctgctggg cgtcgcccgc gaagcccgcg cccacggcga cctcgcctcg gcccaccgct
    13741 ccctgggcga ggccctcgcc ctgtggggcg gggagccgtt caccggcgtg cccggccccc
    13801 acgccgagcg cgagcggacc aggctcgtcc gcctgcggtt ggaggcccag gagcagtact
    13861 tcgattgcgc cctcgacctg ggcatgcacg gccgggtcct gccggagctg tccgcgctcg
    13921 cccgggagca cccgctcgac gagcacctcc agggcctgct gatgcgcgcc ctcgacagct
    13981 gcgggcggca ggccgaggcc ctgaaggtgt acggcgacac ccgccggctg ctcgccgcgg
    14041 aactcggcgt cccgcccggg cgcgaactca cccgcgtccg cgacgggttg gccaccgacg
    14101 ggcgagcggc cagttccggc ccgcccgcca cgccccggtc accggccgcg ggcggagggc
    14161 ccaccggccg ggagggggcg acggtcgagc tggaacggac gctcaccgac ccccgacgcc
    14221 accgggtgcc ggtcgccgtg atcaccggag ccggcggaac cggcaagacg acgctggcga
    14281 cgcgggtggc gcaccgggtc gccgcccact tccccgacgg acggctgtcc gtcgacctgc
    14341 gcgggtcgca ccccacacgg ctccccgagg gcgacgtcct agcccgactc ctccgctccc
    14401 tcggggtccc gcccgaggac gtccccgtcg agacggagca acgggccgcc ctgtaccggt
    14461 ccatgctcgg cggacggcgc atcctgatca tcctggacga cgccgcggac gcggcgcagg
    14521 tcgccccctt gctgcccggc tcgcccggct gcgccgccgt ggtcacggcc cgcagccggg
    14581 ccttcgtcct gcccggcgcc acccagctgg cactcccggc acggcccggg ccggcgaccg
    14641 atcgccgccg gcagctgccg ccccgcctcg ccctcgccct ggactcgctc gccggcagcg
    14701 gagcgccgac cctcccgatc gagctggtcg gcaggctgct gggcaccgac cgggaggagg
    14761 cggagcacat cgccgagtcc ctggtggacg ccgggctact ggacagcccc ggctaccgca
    14821 tgtaccgcat cgcttgcccc gatgcgccgt cgccggacgg cagttgaccc ggtggcggcc
    14881 acccggcgag cggccgagca cgccgccgcg gacggcggcg ctcaggccgc gggggtgtcg
    14941 aacaggtacg cgcgggaggc cgggacctcg gcgcgcaggg cgggcaggtc ccggcacccg
    15001 ctaccggtga tgcgctcgcc cgcgacgttg ttgtcgaaca ggttgcgccc cagaccgcca
    15061 acgccacgcg tggcgttggc ggtctccgcg actccctcgt aacagttgcg atcctcagcc
    15121 gccccgcagg aagaccgcca tcactcatga ggaggccgac gcctccatcg agatgatgct
    15181 gcgatcctcg gtccccctga aaggcagccg ccacaccagc gccagtgagc acgcgtgtca
    15241 tttgggtctc gttacgatcc tcggccgccc gggagggcga ccgccaccag tgcctggccg
    15301 cacaactggt tgtagagctg gctgttgcga tcctcggccg cccgggaggg cgaccgccac
    15361 gccgcctgac cagcgataac tggtgctcca ccgcacggcc atgaggtact ccaaggaccc
    15421 gaatgcactt gatccgggca ttcgcttcgg tgcgaagcgc gtgtcgactt cgggttccga
    15481 accgtgtccg ttgcctgtcg gccgacggcc gcgtggtccg gccatgggga atctgatcgg
    15541 catgaaggac tcaagtagca gtgtgacgcc gctgtgggcg cacagccgga acctatcagg
    15601 ccggcgacac gctctggagg agcacctgcg cggatccgcc gtgctggcag ggcagttcgc
    15661 aactaccttc ggcgccggcg agctagccga gtacctggca ttggtgcaca cgtcggcaag
    15721 ggatcctgtc cctggcagca cggtctgcac accacgaggc ccgcggccgg aaggtcggca
    15781 ttccgcacaa ggaggccggc gcgtggctgg ccgcgtcgca cgccgggcgt ccgttcgccg
    15841 ccgtcgtaca agggcaccac ggcggcctgc ccggataccg ggacctgcag acgctcatcg
    15901 actaggcgaa ggcgcgaact cacaaggacc aggtggtggg gacgcgatct cgggcccgga
    15961 tccgggaggg ctacgatctc gatggcccgc gtgccttcta cgcccacgac ttctcctgag
    16021 tactggtcac gtgctcccga tagcggctcc cttcgacggc ttcggaccga acgaagccgc
    16081 gaccgcccta cgcaagaacg tgaaccagct ttcggacttc atcagccagc gagccttcga
    16141 ccgggtcgtt cggcacggtc agcgccccga tgacctgccg ctcagcgccc gcatacgccg
    16201 acaccacccg ctcgcccgca ggcggctgtc cggcattgat cgtcaccgcg ggcatctccg
    16261 acgtcatctc cgcgagcacc tcggcgaccg tctcccgcgc gatccgcaga cgctccggcc
    16321 tctcccgggc cagctccaac ttggcggaca ccgacgcgag ttcggctgag aactcctcca
    16381 cccgcacccg ggcagccgcc tcgcgggctt ccagctcctc gatcaacgaa cccaccagcc
    16441 gccctcctcg ccaccacggt agagacgaac agccccgggt acagccccga tcagcgttct
    16501 cccagctcag ccgttccctt tcagaagaac cgcaccctta tgggatcgcg aaggtgggcg
    16561 ggtgcggctt tcaggagatt tgcatccaac tcccttgggt acagcccgga tcaaggaact
    16621 gctcccgacc gcgcgggcct gcgcttgctg tccgcaatca accggcctct tcagtatggt
    16681 ggcgctgtga cgcaggcttt tgatgatgac ctgattggcg gtcgatatcg gcttgtgcgc
    16741 caggtggagc ggggcgggat gggtaccgtc tggcaggcgc aggacgagct gctcgaccgg
    16801 accgtggcga cttcacggcc gccgcggcgg ccgcggtccc cctcaccctg ctggccgtga
    16861 ccgcgcgggc ccggtacaca ccgccggagg cgtgaggggg cgctgtcgtc cttcgccagt
    16921 agtccgttcg ccctgctgca cgcgccgccc ggacggtgtt ccgagcggcg cgtgcggagg
    16981 ggcggggtca gagctcctgg tgcccggggt tgaacgaggt gccgaccacc ggagtcagca
    17041 ctgtcctgac gtaacgccgg acgtcgctcg cgttgttgat gcgaatgcca ccgatggtca
    17101 gaggcgccgg gtgggggttg ttgccgaaac cgaggtcgtt ccagaagaag ttggagaggg
    17161 tgccccagtt gttctccatc tgctggagcc aggagggaat gccgctgccc gagttgcccc
    17221 agtcggccag gacgttgcgg aagacaccct cgaggtcgtt gaagcgggcg gcttcggagg
    17281 tgaactggat gagcagcagg agggcgcggg cggtcgtctg ctggttgctg ccggccgacc
    17341 gctggttggc caggtcgagg acggcctggc ggatgctcga gaacgagatg ggggtgttgg
    17401 aacggtcgcg gtgggccgcg ccgaccaggg agttgtagtt cccgccgaac ggcaggttct
    17461 gccgtgcggt ggggatggcc gcgctggcat ggatgtcgtt gaagatgtag gaaacgccgg
    17521 gcgtcgcctg gggtgagtat cccaccaggt agaggttgtc cgggttgatc cacaggtcga
    17581 ccgcccgctc ggtcccgtgg tcgtcgacgg cgctcagtga gactcggacg accccttcgt
    17641 tctgcgaggc ggcctgggcg acctccaccc cctgcaggga gttgccgacc gcggcgcgca
    17701 ggctcgccag gaaggtcgag taggagatgc ggaggttcgg gctgggagcg tggcccaggt
    17761 tcagccagac gtggctcacg gagccgtcgc cggtcgacgc cgaggccgtt ccagcggggc
    17821 acagcaggcc ggccgtgacc gccagtgcca gaaccaggcc ccccactgcc tggcgcagcg
    17881 tccggcggag tctacccaac atgtgcatgt ctgtccgatc gtcagcgtga gcgcaccggg
    17941 cgggcccgga gcgacggagg aagcgggcga gccgaccggt gctccccgca acccgccgac
    18001 ggggttgggc gaccgggcgg cggtcgccct cgcacatgac gctatgtcag caggcccatc
    18061 ggacttgatc gagacggaac gatcgttcgc cgcaccgcgc accgttggca gggcgctacc
    18121 gggtgccgcc gggcggccct cccgggcgct gttcatcaac tcggctgacc tgcacggacc
    18181 tcatgctccg tgaagccggg gccgccggtg gatcctgtac cgccgagatc ggcgagttcg
    18241 gtcgaacgtc cgccgtcaca cagggtggca cagctccccc agagtggcgc gggcgaccga
    18301 gccgagcgct ccggtctcgt cggtactgac ttcggcgcgc cagggtgaat gaccccgaat
    18361 tgcctgacgg gctcggtgcg gtggctgtat ccgatggtgt gtgagatatg cggatggggg
    18421 cgggctgacc gccgcgggac ggctgcgccg ggagtcagtg cggatgcagg ctgccgagct
    18481 gttcgagcag gacgtcaagc cgccggaggt ggctcgacgt ctgcgggtga gcccgaagtc
    18541 ggcttaccag tggcaccaat tgtggtgtga gggcggtgtg caggctctgg cttctcgcgg
    18601 cccgagcggg tcgcggtgtc gtctgtcacc gcgctgcctg gagaaactgg ccgcgtatct
    18661 ggagcagggt ccggctgcgc acggctgggt ggaggaccag gtgtggaccg ccgcgagggt
    18721 ggccacgctg atcgggagga agttccacgt ctcctacagc gtctcgggtg ccacgaggct
    18781 gatgcaccgg ctcggcttca gcccgcaggt ccccgcgcgc cgggtggccg agcgcgacga
    18841 gcaggccgtc accgcgtgga aggaggcgac ctgggcggag gtaaaagagc gcgggcggcc
    18901 tgcgggggct acatctgctt cgaggacgag gcaggattca cccgcagacc gcccaaagga
    18961 cgcacctggg gccgacgagg ccgcacgccg gttgtgaccg tcagcggccg ccgctcggga
    19021 cgcctatccg tggccggggt aatcgccatg cggccgggct cgcgcacccg actgtgccac
    19081 cgcctacaca cccaccccgc aggcagaggc aagcgccgga gcatgggcga gcgcgacttc
    19141 atcgcactga tcgacggcgt ccaccagctg gtcaaggcac cgatcgtgct ggtctgggac
    19201 cgcctgaaca cccacatttc ccatgccatg cgcgacttga tcgccgagcg tgcctggctg
    19261 acggtgttcc tgctccccgc ctattcaccc gacctcaacc ccgtcgaatg ggtctgggcc
    19321 cacgtcgaac gcagcctcgc caacctcgcc gtggtcgccc tcgaccgact cgaagccctc
    19381 gtgcgaaacc ggctcaaacg cctgcagtac cggcccgaca ccctcgacgg cttcatagcc
    19441 ggcaccggcc tgaccctcga cacccccgcc tcaccctgac aagccgaagt cacgttcgtt
    19501 tggacgtcga ggtcgccccg gcgtacgaga aggtgctgga cgcgctacag gcgcgggcca
    19561 ccaccgtggc cgagggcggc gggcagtgag cggggaagct ctgcggtcgg gacaggtcgc
    19621 gacgacctga ccaccatccg cgaagccgtc gcggccggcg ttcagctggc ggacggcgtc
    19681 tcctgcgacc cgacctgtca cgtcatcggc cccgacggcc gtgcgctgga gggcatcgtc
    19741 gccgccggtg acgtcgccgc cataacggac cgccggtgtg cggaccggtc attcgaccag
    19801 tccgcacacc ggcggtgtca ctcgggtcag cgagaaggat cagtcgtccg tctcgtcgta
    19861 ccgaccgtgg ccgaggcggc gcaggtcgaa ggaccagatg ccgcggccga aggtggcggc
    19921 gtagagcttg ccgtcggggc cgatcttgag ctgctgcacc gaggtggtgg gcaggttgcg
    19981 gccgagcacc ctgaagtcgg tggcaccggg cgcgcggtag aacgcggcga ggtcggtacc
    20041 gagggcgagg ccgccgttcg gcaacagctt gatcgaggtg gcggggacgt ctggcaggtt
    20101 ggccgagacg tccgtccagc tcgcaccgcc gtcacgggtc tcgaagaggt ggccgatccc
    20161 ggcgcccggg ccctcggtcc agctgcggga gaagccgctg aacgcgacga agacgtgctg
    20221 ggcgtcgttc tcgtcgaccg cgaaggagga gacgtaccgg ttgggcaggg tgccgtcgac
    20281 gggcaggttg agctggtgcc agccggtgcc gtcggtgttc ccgaccgcga taccgcgggt
    20341 gaagccctgg ttgttgcagg ggccgcacca gcccgcgtac accgtgccgt tgacggtggc
    20401 cacggccgtg gcgacgtggc cggcgcccag gtcgtaggcg gaggtccact cgctgccgct
    20461 gcggatcgcg tagcccttgt gctgcaccca gacgtgctgg ccgcccgcga tccaggtgtt
    20521 ggtgtccttg gggtcggtgg tgatcggggc gatgaagcgg gcggcgctgg tggccttgtc
    20581 gggcggtgcg acctcgtagg aggtggcctt gctcgggtcc ctcgtccaac ttccgtcgtt
    20641 caccgcgcag ttctgggtga cccacatgtc caggtagacg tactcctcgc cgatgttgca
    20701 gccgttggcc gggtcgacca gggtgtctcc gccgtcgccg ccgaaattgg agcccatcac
    20761 cttgtcgtgg gcgcgcagga tcgattcgcc gttgtcctgg agcccgccgc tgacgatcac
    20821 gccccggccg gagcggtccg ccaggtcctt gccgatgccc accgagtagt actgcagggt
    20881 gtcgatcgtc ccgtcgttga gggacttcca gtccttggcg tgaccgcccg cgtccaactg
    20941 cccgttgacc gggcgggtgt agatgccgcc gtcgttgccg acgtagacgc tcgtcttgcc
    21001 ctggtagctg ccgatggcga cggcgtgctg gtccgagtgc gtcgtcggcg agcagtcgcc
    21061 ggtctgcttg gcggggtcga tgctccagca cgggaacggg ttgttccagt acggggcgac
    21121 agtggcccac ttggcgccgc cgtcggtggt ctcgaagacc tcttccaggc ccgcccagac
    21181 gtggtccggg ttggccgggt cgacctggag gaactggttg taccaggact ggatgccggg
    21241 ctggtagccc gcgtcctgga gcgccgagcc ggagcccttg agcttgtcct tgtccgcgat
    21301 cagggcccac gggccggccg gggaaccgga cttggagacg tagatcccct tgaggccggt
    21361 gtccgggttg tgcgccatga cgtccggcga ctggtcgatc gcgtagtagc gcgagccgtc
    21421 cgccgagcgc gcgaaggtca cgttgccgac gttggcagcg tccgtcggca ggtcacccag
    21481 cgaggccacc cgctgccaac tgccgtcggc cgccttgctg tagaagccgt tgtaggtgtc
    21541 gccgccacgc cagccgaccg ccaggatcac cttggacggg tccttggagt cgatggcgat
    21601 gtcgttggcg atgttcttgt acggcgcgct cgggtcgctc gccttcgcac cgccgggcag
    21661 gtaatcgggg ttgggcgcga actccatggt ccacgggccg gacagatcgg tggtggagtg
    21721 gctccacacg ccccggttgg ttgccgccca caccttgtcc ccggcgaagc gcagctggtg
    21781 gatcgtggtg gactccagct cggcgccgcc gacccggttc ccgggctgga acttgccgtg
    21841 cttcgggtcg gacagcacgt acacaccggt gccgacgtac gaggtcgcgc cggtgttgga
    21901 ctcaccggtg gcgtaccaga gccgcccgcc gccgtccagg ttcagggtgc cggtggacag
    21961 cgtgggcaac ttgtcggcga tcggctccca gtggccgccg ccggtgcggg agcggaacac
    22021 gccgccgttg gcgccgcccg cgtagacgta gccgtcggag tcggccgcga tgccggtgat
    22081 ccggcccgtg acgaagccgg cgccgccgct ggagttggag ttgacgtcgc ggtagcgcgg
    22141 gtcgtcgccg ttgtacggct tgttcgtcac gtggtcccag gaaccgccgg tgtgcggcag
    22201 cgactggagc tgggcccagg ccgcgccgta cgcgcccggc gcgacgacgc cgggggcggt
    22261 gcgggcctcg gtgtactgcg cggtgccctc ggctgagttc tccgcctcgt cgctgccgcc
    22321 gtcgccaccg gtctcggcct tggcggagaa ggtgtggccg cccgccggct tgcccgtgac
    22381 cttctgggcg tgcctctggc cggcctcggt caggcgctgc accgggttcg gctgggttcc
    22441 gggctgtgcg acgggtgcgg ccatggcctg agtggcggtc aggccgagcg cggtgagcgt
    22501 gacggcgctc agcagcagcc gtcgtcgttg cctgttcggc acgg
//
