LOCUS       NZ_CP114205            21062 bp    DNA     linear   CON 09-NOV-2024
DEFINITION  Streptomyces tubercidicus strain DSM 40261 chromosome, complete
            genome.
ACCESSION   NZ_CP114205
VERSION     NZ_CP114205.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces tubercidicus
  ORGANISM  Streptomyces tubercidicus
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8284047)
  AUTHORS   Ruckert,C., Busche,T., Kalinowski,J. and Wittmann,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-DEC-2022) CeBiTec, Bielefeld University, Sequenz 1,
            Bielefeld, NRW 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 02-MAR-2022
            Assembly Method                   :: flye v. 2.9; Newbler v. 2.8
            Assembly Name                     :: DSM40261_v1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 133.7x
            Sequencing Technology :: Oxford Nanopore GridION; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/09/2024 02:53:13
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,167
            CDSs (total)                      :: 7,077
            Genes (coding)                    :: 6,906
            CDSs (with protein)               :: 6,906
            Genes (RNA)                       :: 90
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 171
            CDSs (without protein)            :: 171
            Pseudo Genes (ambiguous residues) :: 0 of 171
            Pseudo Genes (frameshifted)       :: 72 of 171
            Pseudo Genes (incomplete)         :: 133 of 171
            Pseudo Genes (internal stop)      :: 9 of 171
            Pseudo Genes (multiple problems)  :: 41 of 171
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 18:04:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5251418
            Orig. end                         :: 5272480
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP114205.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from DSM 40261.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21062
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="20"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21062
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21062
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11062](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11062)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            <137..1027
                     /db_xref="GeneID:96285455"
                     /locus_tag="STRTU_RS22885"
                     /old_locus_tag="STRTU_004576"
                     /pseudo=""
     CDS             <137..1027
                     /codon_start=1
                     /db_xref="GeneID:96285455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015033793.1"
                     /locus_tag="STRTU_RS22885"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_004576"
                     /product="chitinase"
                     /pseudo=""
                     /transl_table=11
                     /translation="TGFAPYVDTSLSPAYDLVGTAKKTGAKDFHLAFVTSGGGCVPKWG
                     GAGELGDDPVARQIPALRKAGGDVRISFGGANGSELGLACGSADELAAAYGKVIDRFEL
                     TKADFDIEGGALPDTAANTRRAQAIHKLQKKHPGLDVSFTLPVMPEGLTQDGVNLIADA
                     RKNGVKISAVNIMAMDYGPAYSGDMGTYATQAATATQAQIKKALGLSDAAAWKTVAVTP
                     MIGVNDVATEVFRRDDATELVKFARSKHLAWLSMWSSTRDQACPGGTGTSAQPTCSSIE
                     QQPLDFTRAFAAYKG"
     tRNA            complement(1239..1314)
                     /anticodon=(pos:complement(5252697..5252699),aa:His,
                     seq:gtg)
                     /db_xref="GeneID:96285456"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="STRTU_RS22890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="STRTU_004577"
                     /product="tRNA-His"
     gene            complement(1239..1314)
                     /db_xref="GeneID:96285456"
                     /locus_tag="STRTU_RS22890"
                     /old_locus_tag="STRTU_004577"
     gene            complement(1477..2094)
                     /db_xref="GeneID:96285457"
                     /gene="orn"
                     /locus_tag="STRTU_RS22895"
                     /old_locus_tag="STRTU_004578"
     CDS             complement(1477..2094)
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0000175 - 3'-5'-RNA exonuclease activity
                     [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96285457"
                     /gene="orn"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018542190.1"
                     /locus_tag="STRTU_RS22895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_004578"
                     /product="oligoribonuclease"
                     /protein_id="WP_159745698.1"
                     /transl_table=11
                     /translation="MNDRMVWIDCEMTGLSLANDALIEVAALVTDSELNVLGDGVDVVI
                     RPPAEALGTMPEVVRQMHTASGLLEELDSGTTLEAAEAQVLAYIKQHVREPGKAPLCGN
                     SVGTDRGFLLRDMPTLESFLHYRIVDVSSVKELARRWFPRAYFNSPPKNGNHRALADIR
                     ESIAELRYYREAVFVPQPGPDSDTAKAIAAKHVLPTEPQSTP"
     gene            complement(2100..3380)
                     /db_xref="GeneID:96285458"
                     /locus_tag="STRTU_RS22900"
                     /old_locus_tag="STRTU_004579"
     CDS             complement(2100..3380)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96285458"
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014179481.1"
                     /locus_tag="STRTU_RS22900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_004579"
                     /product="GlxA family transcriptional regulator"
                     /protein_id="WP_159745700.1"
                     /transl_table=11
                     /translation="MSQDSAAVPDAARKLAARRRREIVAVLLFSGGPIFESSIPLSVFG
                     IDRQDAGVPRYRLLVCAGEDAPLRTTGGLELSAPYGLEAISRAGTVVVPAWRSITQAPP
                     PAALDALRRAHEEGARIVGLCTGAFVLAAAGLLDGRPATTHWMYAPTLAKRYPSVHVDP
                     RELFVDDGDVLTSAGTAAGIDLCLHIVRTDHGADAANALARRLVVPPRRTASDMGHQRY
                     LDRSLPEEIGADPLAEVVAWALEHLHEQFDVETLAARAYMSRRTFDRRFRSLTGSAPLQ
                     WLITQRVLQAQRLLETSDYSVDEVAGRCGFRSPVALRGHFRRQLGASPAAYRTAYRARR
                     PQNGGPDPALRPERADRPERERAMLGAGSGERYAAAALAGHGLATAEAAEAGKPQSDAY
                     AARLPESPVGRGTGRPVLPGQRERPVG"
     misc_feature    complement(2700..2702)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(3538..3551)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.23"
                     /tool="antismash"
     misc_feature    complement(3691..3705)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.26"
                     /tool="antismash"
     gene            complement(3730..4002)
                     /db_xref="GeneID:96285459"
                     /locus_tag="STRTU_RS22905"
                     /old_locus_tag="STRTU_004580"
     CDS             complement(3730..4002)
                     /codon_start=1
                     /db_xref="GeneID:96285459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605444.1"
                     /locus_tag="STRTU_RS22905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_004580"
                     /product="hypothetical protein"
                     /protein_id="WP_159745702.1"
                     /transl_table=11
                     /translation="MSDVVRWGAFSCALVPLVLIFSGVSWAGAAGAGAGLAAVTGACRA
                     LLRHSERTAARVRVREVGRHRDRNGRSGVTAHGGGRHSEGRTPVD"
     misc_feature    complement(3862..3864)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(4268..4282)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.57"
                     /tool="antismash"
     misc_feature    complement(4269..4284)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.6"
                     /tool="antismash"
     gene            4411..4932
                     /db_xref="GeneID:96285460"
                     /locus_tag="STRTU_RS22910"
                     /old_locus_tag="STRTU_004581"
     CDS             4411..4932
                     /GO_function="GO:0032559 - adenyl ribonucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96285460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018105726.1"
                     /locus_tag="STRTU_RS22910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_004581"
                     /product="universal stress protein"
                     /protein_id="WP_159745704.1"
                     /transl_table=11
                     /translation="MAGHEIPEPANRKQVADPMADLEAAEKTRHSCDPAFRHGVVVGFD
                     GSMSSERALAYAIGMARRLGSGLIIVHVANRLPTTVWAGCEPPVFVDVPDHRTEVLGLE
                     LACADHLSEVPWILVERGGDICHELEEVGREYEADAIVVGSTHGIVGRIFGSVAGRLAR
                     RAQRPVIVIP"
     gene            complement(5072..6892)
                     /db_xref="GeneID:96285461"
                     /gene="glmS"
                     /locus_tag="STRTU_RS22915"
                     /old_locus_tag="STRTU_004582"
     CDS             complement(5072..6892)
                     /EC_number="2.6.1.16"
                     /GO_function="GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA]"
                     /GO_process="GO:0006040 - amino sugar metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96285461"
                     /gene="glmS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980526.1"
                     /locus_tag="STRTU_RS22915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_004582"
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="WP_159745706.1"
                     /sec_met_domain="GATase_7 (E-value: 3.6e-15, bitscore:
                     54.6, seeds: 307, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGIVGYIGKRDVAPLLIEGLQRLEYRGYDSAGIAIHAKGTAGGL
                     KTAKAKGRVRELESRLPKRFAGSTGIAHTRWATHGAPTDENAHPHQDTEGKVAVVHNGI
                     IDNAADVRAKLTADGIVFASETDTEVLAHLIGRSTAEKLEEKVREALRHIEGTYGIAVL
                     HADFPDRIVVARNGSPVVLGIGEHEMFVSSDVAALVSHTRQVVTLDDGEMATLKADDYR
                     TYTTEGSRTTSAPETVEYAAESYDLGGHDTYMHKEISEQADAVDRALRGRIDDRFSTVH
                     LGGLNLDARAARGVRRVKILGCGTSYHAGQIGAQMIEELARIPSDAEPASEFRYRNPVV
                     DPDTLYVAVSQSGETYDVLAAVQELKRKGARVLGLVNVVGSAIARETDGGIYVHAGPEV
                     CVVSTKCFTNMVVSFALLALHLGRIRDLSVADGKRIIEGLRKLPAQIDEILKGEEDIKK
                     LSAAYADAKSMMFIGRVRGYPVAREASLKLKEVSYIHAEAYPASELKHGPLALIEPAMP
                     TVAIVPDDDLLEKNRAALEEIKARSGRILAVAHQEQEKADHTILVPKNEPELDPILMGI
                     PLQLLAYHTALALGRDIDKPRNLAKSVTVE"
     misc_feature    6857..6871
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.58"
                     /tool="antismash"
     gene            complement(6960..7250)
                     /db_xref="GeneID:96285462"
                     /locus_tag="STRTU_RS22920"
                     /old_locus_tag="STRTU_004583"
     CDS             complement(6960..7250)
                     /codon_start=1
                     /db_xref="GeneID:96285462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605447.1"
                     /locus_tag="STRTU_RS22920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_004583"
                     /product="hypothetical protein"
                     /protein_id="WP_159745708.1"
                     /transl_table=11
                     /translation="MLERRHRSAEAPHEDLVDHLVRSTPLQRGEAARVVLDVLAYFDET
                     TEEFVRRRHRELQSQGLRNEAIFERIRHEMPHRAVAPPDLSTRQLRRLIYG"
     misc_feature    7344..7357
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 20.35"
                     /tool="antismash"
     gene            7440..9044
                     /db_xref="GeneID:96285463"
                     /locus_tag="STRTU_RS22925"
                     /old_locus_tag="STRTU_004584"
     CDS             7440..9044
                     /codon_start=1
                     /db_xref="GeneID:96285463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018093090.1"
                     /locus_tag="STRTU_RS22925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_004584"
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="WP_159745710.1"
                     /transl_table=11
                     /translation="MRRRRLLFSLLLVAAAGLGTAAVPPPGAAGAAPRAATPLDRVIPA
                     PASVRGGGDAYTLGDRTRIRVPGGSGEAKRIAGYLAGLLRPATGLALPVTTKDGRDGIV
                     LRLGGSGTGGLGAEGYRLTSDGRAVTLSAARPAGLFHAVQTLRQLLPADAERQRARRGP
                     WRIAGGTITDSPRYGYRGAMLDVSRHFFTVAQVKRYIDQLAMYKINRLHLHLSDDQGWR
                     LAIKSWPRLATYGGSTQVGGGRGGYYTQDDYREIIRYAASRYLTVVPEIDMPGHTNAAL
                     ASYAPLNCNGQAPPLYTGTEVGFSSLCVPKRETYDFVDDVIRELAALTPGRYLHIGGDE
                     AHSTSHADYVAFMDKVQPVVAKYGKTVVGWHQLTGAHPAKGAAAQYWGYDKTGAAERQQ
                     VADAARNGTRLILSPADRAYLDMKYDKDTPLGLSWAGYVDTRRSYDWDPGSYLQGAPAG
                     SILGVEAPLWTETLKTSADIEYMAFPRLPGIAELGWSPASSHDWDDYKVRLAAQGPRWD
                     ALGMNYHRAPEVPWPAR"
     gene            complement(9093..9968)
                     /db_xref="GeneID:96285464"
                     /locus_tag="STRTU_RS22930"
                     /old_locus_tag="STRTU_004585"
     CDS             complement(9093..9968)
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0042214 - terpene metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96285464"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016574303.1"
                     /locus_tag="STRTU_RS22930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_004585"
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_159745712.1"
                     /transl_table=11
                     /translation="MSIAHADTARTPVPTQSTYQSRVADYWNAEENPVNLELGKIDDLY
                     HHHYGIGEADRSVLNEPDPVRRRERITGELHRLEHAQAELLASRLGDLSPTDRVFDAGC
                     GRGGGSVVAHLRHGCHTDGATISAKQADFANAQARKRGIDDKVRYHHRNMLDTGFTSGA
                     YAASWNNESSMYVELDLLFAEHARLLRRGGRYVTITGCYNDTYGRASREVSLINAHYIC
                     DIHPRSEYFRAMARNRLVPVHVEDLTEAALPYWELRREADHLVTGIEDTFLTAYRNGSF
                     QYLLIAADRV"
     gene            complement(10001..11062)
                     /db_xref="GeneID:96285465"
                     /locus_tag="STRTU_RS22935"
                     /old_locus_tag="STRTU_004586"
     CDS             complement(10001..11062)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96285465"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018093087.1"
                     /locus_tag="STRTU_RS22935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_004586"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_159745714.1"
                     /sec_met_domain="T1TS (E-value: 2.7e-51, bitscore: 174.0,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTPPNPAAAYALPGPPNLARTLRTRRPGGAVPGLRYRPAAPADP
                     ETAAEVDRRLETWARQLDLFPAQWSGDFTQFQFGRAVALQHPGAADLDRLTVAGKLLLA
                     ENIVDTCYCEEDEGKGGAHRGLGGRLIMAQSALDPFHGTPELEAEWRQGVQADGPLRSY
                     HWALKDYAALATPSQADRFVQDIARLHLGYLAEAAWAETRHAPRVWEYLVMRQFNNFRP
                     CLSIVDAVDGYELPEALYARPEVQRVTALACNATTIVNDLYSFTKELASDPDHLNLPQV
                     VAANDKRGLKAAYLKSVEIHNRVMEAFETESAPLAALSPLLERYVRGLADWVSGNHEWH
                     ATNTDRYHLPHYW"
     gene            complement(11082..12524)
                     /db_xref="GeneID:96285466"
                     /locus_tag="STRTU_RS22940"
                     /old_locus_tag="STRTU_004587"
     CDS             complement(11082..12524)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96285466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016576907.1"
                     /locus_tag="STRTU_RS22940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_004587"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_159745716.1"
                     /transl_table=11
                     /translation="MSVPDSVTGSTSDEPALAAPADSALTSLSTQAARQLATTTKSEPQ
                     MQAITSRWLLKTLPWVDVKGGAYRVNRRLQLRVGRGRVQFEQNGADDIRVIPQTLTELP
                     ALRGYSDTEVLKELAGRFRVREVRAGQVLFEAGQPTTEAYLVVHGRFARYTVGKYGEEE
                     VIGVVTDGDQMGDEAIGRPDPRWLSSVRAETAGVVMALPWDVVREFTDRAPSLAAHLSA
                     YAERQQRPMNRKGEAEVPVRAGHVGEPTLSSGFVDYDLAPREYELSLTQTVLRVHSRVA
                     DLYNDPMDQTQQQLRLTVEEIRERQEWELVNNREFGLLHNADYGHRISTYTGPPTPDDM
                     DELLSMRRKTRLFLAHPKAIAAFFRQCNKRGLVPGTATVDGHEVPAWRGVPIYPCGKIP
                     ISDTQTSSILALRTGEADQGVVGLHQTGIPEEYQPGLNVRFMGIDPAAVISYLVTAYYS
                     LAILVPDAVGVLENVQTGRSAD"
     gene            complement(12859..14010)
                     /db_xref="GeneID:96285467"
                     /locus_tag="STRTU_RS22945"
                     /old_locus_tag="STRTU_004588"
     CDS             complement(12859..14010)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96285467"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006376616.1"
                     /locus_tag="STRTU_RS22945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_004588"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_159747161.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 7.3e-37, bitscore:
                     125.2, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 8.3e-21, bitscore:
                     72.7, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 2.3e-49, bitscore:
                     166.2, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDHRLSAELEELRRTVEAFAHDVVAPKIGEYYEQHAFPYEIVQEM
                     GRMGLFGLPFPEEYGGMGGDYLALGIALEELARVDSSVAITLEAGVSLGAMPVYHFGTE
                     EQKRAWLPKLCSGEMLGAFGLTEPDGGSDAGATRTTAVRDGGDWVINGSKCFITNSGTD
                     ITGLVTVTAVTGRKDDGSPLISSIIVPSGTPGFTVGAPYSKVGWSASDTRELSFAGVRV
                     PAANLLGEEGRGYAQFLRILDEGRIAIAALATGLAQGCVDESVRYAKERRAFGRAIGSN
                     QAIQFKLADMEMRAHTSRLAWRDAASRLVHGEPFKKEAALAKLYSSEIAVDNAREATQI
                     HGGYGFMNEYPVARMWRDAKILEIGEGTSEVQRMLIARELGVG"
     gene            complement(14022..14963)
                     /db_xref="GeneID:96285468"
                     /locus_tag="STRTU_RS22950"
                     /old_locus_tag="STRTU_004589"
     CDS             complement(14022..14963)
                     /codon_start=1
                     /db_xref="GeneID:96285468"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015577261.1"
                     /locus_tag="STRTU_RS22950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_004589"
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="WP_159745718.1"
                     /sec_met_domain="HMGL-like (E-value: 1.3e-46, bitscore:
                     158.0, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAAGLPMEIRAEGLPTRVRIHEVGARDGLQNERTVVPTEIKAEF
                     IHRLAAAGLPTVEATSFVHPKWVPQLADAEQLFPLLADLDPHRLPVLVPNERGLDRALA
                     LGARRIAVFGSATESFAKANLNRTVDEALAMFAPVIARAKDAEVHVRGYLSMCFGDPWE
                     GPVPVAQTVRVCRELLDLGCDELSLGDTIGVATPGHVQTLLAALNEAGVPTSRIGVHFH
                     DTYGQALANTFAALQHGVTTVDASAGGLGGCPYAKSATGNLATEDLVWMLHGLGIETGV
                     DLDRLTATSVWMAEALGRPSPSRTLRALSHKE"
     gene            complement(14963..16972)
                     /db_xref="GeneID:96285469"
                     /locus_tag="STRTU_RS22955"
                     /old_locus_tag="STRTU_004590"
     CDS             complement(14963..16972)
                     /EC_number="6.4.1.2"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96285469"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605451.1"
                     /locus_tag="STRTU_RS22955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_004590"
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="WP_159745720.1"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 2.4e-08,
                     bitscore: 32.4, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATNFDTVLIANRGEIAVRVIRTLRALGIRSAAVYSDADADARHV
                     READTAVRIGPAAAAESYLSVERLLEAAVRTGAQAVHPGYGFLAENAAFARACADAGLV
                     FIGPSADAIELMGDKIRAKETVREAGVPVVPGSSGSGLDDGQLAAAAREIGMPVLLKPS
                     AGGGGKGMRLVREEALLADEIASARREARSSFGDDTLLVERWIDRPRHIEIQVLADGHG
                     NVIHLGERECSLQRRHQKVIEEAPSVLLDEATRAAMGEAAASAARSCGYRGAGTVEFIV
                     PGKDPASYYFMEMNTRLQVEHPVTELVTGLDLVEWQLRVAAGERLPYAQEDITLTGHAI
                     EARICAEDPARDFLPTGGTVLTLHEPEGGGVRTDSGLSEGGEVGSRYDPMLSKVIAHGP
                     DRASALRRLRAALAGTVTLGVTTNAGFLRRLLAHPDVVSGELDTGLVEREAAGLVDGTV
                     PDEVYAAAAAVRQAALEPAVADGGWRDPFAAPNGFRLGGEPAPVRHWLRVPGHDPVAHD
                     VRPDAAAAQVTPDRVRVTVDGVLHTFHHSGDWLGRDGDSWQVTTHDPVAAALRGAAGAH
                     GADTLAAPMPGTVTVVKVAVGDEVAAGQGLLVVEAMKMEHVISAPHAGTVAELDVTAGS
                     TVAMDQILAVVAPHESPEEPAASAGAPEGGQESA"
     gene            complement(16990..18657)
                     /db_xref="GeneID:96285470"
                     /locus_tag="STRTU_RS22960"
                     /old_locus_tag="STRTU_004591"
     CDS             complement(16990..18657)
                     /codon_start=1
                     /db_xref="GeneID:96285470"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003983282.1"
                     /locus_tag="STRTU_RS22960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_004591"
                     /product="carboxyl transferase domain-containing protein"
                     /protein_id="WP_246241064.1"
                     /transl_table=11
                     /translation="MEQAPVLGSDGGPPARAQSSVGDDPASDSWRANEAAHRELAAELR
                     EKLAAARLGGGEKARARHTARGKLLPRDRVDALLDPGSPFLEVAPLAADGMYGGAAPAA
                     GVIAGIGRVSGRETVIVANDATVKGGTYYPMTVKKHLRAQEIALENRLPCLYLVDSGGA
                     FLPMQDEVFPDREHFGRIFYNQARMSGAGIPQIAAVLGSCTAGGAYVPAMSDEAVIVRN
                     QGTIFLGGPPLVKAATGEVVTAEELGGGEVHAKTSGVTDHLAEDDAHALRLVRTIVGTL
                     GEREPLPWTVRTVEEPKVDPAGLYGAVPADSRTPYDVREVIARLVDGSRFAEFKAEYGT
                     TLVTGFAHLHGHPVGIVANNGILFSESAQKGAHFIELCDQRGIPLLFLQNISGFMVGRS
                     YEAGGIAKHGAKMVTAVACTRVPKLTVVIGGSYGAGNYSMCGRAYSPRFLWMWPNAKIS
                     VMGGEQAASVLATVKRDQLEAHGEEWSAEEEAAFKAPVREQYETQGNAYYATARLWDDG
                     VIDPLETRQVLGLALTACANAPLPQKDSTAPGYGVFRM"
     gene            18793..19434
                     /db_xref="GeneID:96285471"
                     /locus_tag="STRTU_RS22965"
                     /old_locus_tag="STRTU_004592"
     CDS             18793..19434
                     /codon_start=1
                     /db_xref="GeneID:96285471"
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018093080.1"
                     /locus_tag="STRTU_RS22965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_004592"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_159745723.1"
                     /transl_table=11
                     /translation="MSNAQSSAPTSRREQILKEAARLFAERGFHGVGVDEIGAAVGISG
                     PGLYRHFAGKDAMLAELLVGISERLLAGGRMRVTEGGGSPEAVLDALIDGHIDFALDDR
                     PLITLHDRELDRLREADRKRVRQLQRQYVELWVEVVREAYPVCVEAEARSAVHAVFGLL
                     NSTPHLGRPGALPGRTEMAELLHRLALGAFGAVAGEPSAGESMAAAVPGA"
     gene            19560..20717
                     /db_xref="GeneID:96285472"
                     /locus_tag="STRTU_RS22970"
                     /old_locus_tag="STRTU_004593"
     CDS             19560..20717
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96285472"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003969014.1"
                     /locus_tag="STRTU_RS22970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_004593"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_159745725.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 4.3e-29, bitscore:
                     100.2, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 7.2e-26, bitscore:
                     88.9, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 8.3e-45, bitscore:
                     151.4, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRTVFNEDHEAFRATIRAFIEAEVVPVYDEWLAAGQAPRDFYYK
                     LGELGVFGIRVPEEFGGAGIESHKFEAVMYEETSRAGVSFGGSGVHVLLGLPYIEMLAT
                     DEQKKRFLPKFVTGEEMWALAMTEPGTGSDLAGMKTTAKLSDDGTHYVLNGAKTFITGG
                     VHADRVIVCARTAAPREDDRRFGISLFAVDTKAEGYSVGRKLDKLGLKTSDTAELAFVD
                     VKVPVEDLLGEENKGFGYLGLNLASERWGIAFGAYAQAKAAVRFAKEYVQERTVFGKPV
                     AAFQNTKFELAACQAEVDAAEAVADRALEALDAGELSPAEAASAKLFCTEVAHRVIDKC
                     LQLHGGYGFMNEYPIARLYADNRVNRIYGGTSEVMKMIIAKSMGL"
ORIGIN
        1 gcgcaagagc cgcaccaccc agctgatcgt gaccggggcg gccgccgcga tcgcggccgg
       61 cggggccttc gccctcgccg gctccgccct ggccgccaag gcaccgcaga ccgccggcac
      121 ccccgcgaaa gcggccaccg gcttcgcccc gtacgtcgac acctcgctca gtcccgccta
      181 cgacctggtc ggcaccgcca agaagaccgg ggccaaggac ttccacctcg ccttcgtcac
      241 ctccggcggc ggctgtgtgc ccaagtgggg cggcgcgggc gagctgggcg acgacccggt
      301 ggcccggcag atccccgcgc tgcgcaaggc cggcggcgac gtccggatct ccttcggcgg
      361 cgccaacggc tccgagctcg gtctggcctg cggctccgcg gacgaactgg ccgccgccta
      421 cggcaaggtc atcgaccggt tcgagctcac caaggccgac ttcgacatcg agggcggcgc
      481 actgccggac accgccgcca acacccgccg cgcccaggcc atccacaagc tccagaagaa
      541 gcaccccggc ctcgatgtct ccttcaccct gccggtcatg cccgagggcc tcacccagga
      601 cggcgtgaac ctgatcgccg atgcccggaa gaacggcgtc aagatctccg ccgtcaacat
      661 catggcgatg gactacggtc ccgcctacag cggcgatatg ggcacctatg ccacccaggc
      721 cgccaccgcc acccaggccc agatcaagaa ggccctcggc ctgagcgacg cggccgcctg
      781 gaagaccgtg gcggtgaccc cgatgatcgg cgtcaacgat gtcgcgaccg aggtcttccg
      841 ccgcgacgac gccaccgagc tggtgaagtt cgcccggtcc aagcacctgg cctggctgtc
      901 gatgtggtcc tcgacccgcg accaggcatg ccccggcggc accggcacct ccgcacagcc
      961 gacctgcagc tccatcgagc agcagccgct ggacttcacc agggccttcg ccgcctacaa
     1021 gggctgaccc ccaccggcgg tccggtaccc cctgcccgga ccgtccgccc cagccggggc
     1081 gcagcgggct cccccccacc cgctgcgccc cgccactccc tccatgcggc acgccgccgg
     1141 accctttgcc ccatccatcc caaatgttcg gcttatgccg cctcggcggt accccgacaa
     1201 acgccaaggc ccccgacctg aggtcggggg ccttgaagtg gggtgagtaa cgggacttga
     1261 acccgcgaca tcctggacca caaccaggtg ctctaccagc tgagctatac ccaccatgac
     1321 cggtgctgtg tggttctttt tccccaccgg ctgagaaaaa gtgtacaggg tccggagggg
     1381 tgctcgcgcc caggtttcgc gtcccgggcc cgagggcgtg tcgtgcgggt cacggtggcc
     1441 ccgtgggggg ccgcacgaca gccgccctgt gccttgctac ggcgtggact gcggttcagt
     1501 cggaaggacg tgcttggcgg cgatcgcctt cgcggtgtcc gagtccgggc cgggctgcgg
     1561 cacgaagacc gcctcccggt agtagcgcag ctccgcgatg gattcacgga tgtccgccag
     1621 cgcccggtgg ttgccgttct tgggcggact gttgaagtag gcccgcggga accagcgccg
     1681 ggccagttcc ttcacggacg agacatcgac gatccggtag tggaggaagc tctccagcgt
     1741 cggcatgtcg cgcagcagga agccacggtc ggtgccgacg gagttgccgc acagcggcgc
     1801 cttccccggc tcccgcacat gctgcttgat gtacgcgagc acctgggcct ccgccgcctc
     1861 cagcgtcgtc ccgctatcga gctcctccag cagcccggag gcggtgtgca tctggcgcac
     1921 cacctccggc atggtgccga gtgcctcggc gggggggcgg atcaccacat ccaccccgtc
     1981 gcccagcaca ttcagctccg agtcggtgac cagggcggcc acctcgatga gcgcgtcatt
     2041 cgccagcgag aggccggtca tctcgcagtc gatccacacc atgcgatcgt tcatacatct
     2101 caccctacgg ggcgctcccg ctgtccgggc agcacggggc gtccggtacc ccggcccacc
     2161 ggggactccg gcagccgggc ggcgtaggcg tccgactgcg gtttgcccgc ctcggccgct
     2221 tcggcggtcg ccagcccgtg cccggccagc gcggcggcgg cgtaccgctc cccgctgccc
     2281 gcgcccagca tcgcccgctc acgctccggc cggtccgcgc gctccggtct gagcgcgggg
     2341 tcgggccccc cgttctgcgg ccgccgcgca cggtaggccg tgcggtacgc ggcgggggag
     2401 gcgcccagct gcctgcggaa gtggccgcgc agggcgaccg gcgagcggaa cccgcagcgc
     2461 ccggcgacct cgtccaccga atagtcggag gtctccagca gccgctgggc ctgcagtacc
     2521 cgctgggtga tcagccactg cagcggagcg ctccccgtca gggaccggaa gcgccggtcg
     2581 aaggtgcgcc ggctcatata ggcgcgcgcg gccagcgtct ccacgtcgaa ctgctcgtgg
     2641 aggtgctcca gcgcccaggc gacgacctcg gccagcgggt cggcgccgat ctcttcaggt
     2701 aatgacctgt ccaggtagcg ctggtgcccc atatcggacg cggtgcggcg cggcggcacg
     2761 acgagccggc gggccagcgc gttcgcggcg tccgcgccgt ggtcggtgcg cacgatgtgc
     2821 agacacagat cgataccggc cgccgttccc gcggaggtga gcacatcgcc gtcgtcgacg
     2881 aagagctcgc gggggtccac atggacggac gggtaacgct tggcgagcgt cggtgcgtac
     2941 atccagtggg tggtggccgg gcggccgtcg agcagtccgg ccgcggcgag gacgaacgcc
     3001 cccgtgcaca gcccgacgat tctggcgccc tcttcatgcg cccggcgcag cgcgtcgagc
     3061 gcggcgggcg gcggggcctg ggtgatggaa cgccaggccg gtacgacgac cgtcccggca
     3121 cgggagatcg cctccagccc gtagggggcg gacagttcga gccccccggt cgtgcgcaaa
     3181 ggcgcatctt cgcccgcgca cacaagcagc cggtaccgcg ggacgcctgc gtcctgtcgg
     3241 tcgatgccga agaccgagag cggaatggag ctctcgaaaa tggggccgcc actgaagagg
     3301 agcaccgcga ctatttcgcg gcgtcgtcgg gcggcgagct tgcgtgcggc atctggtacg
     3361 gcagcggagt cctggctcat ggcacttaag cccccctcgg tcgtctcgcc ctctcggtcc
     3421 tgcacagttc ccccgccatt gctaccaaga tcgaatctac tgtgttccgt gaggatggag
     3481 tgccaagttc accacccgct ggtatgtcga tatggcaact tggcgcgaag cattcgatca
     3541 cgaagcgttc cactcgtcgg gcctacatgg gaagtacgcg tctcggctct gcccgttcgc
     3601 agtagggcac aaccatgccc agcggtcctt tcctccctgc tcacaccagg gttgaggggt
     3661 actcaggact aggtatggac ctcggccgga agttggctga aaacggtcgc gcgcagaggt
     3721 gtcggcgcct caatcgaccg gcgtacgccc ttcggagtgc cggccgcccc cgtgcgccgt
     3781 cacccccgaa cgtccgtttc tgtcccggtg tcgtccgacc tcgcgcaccc ggacccgggc
     3841 ggcggtccgc tcggagtgcc gtaacagtgc gcggcaggcg ccggtcaccg cggccagacc
     3901 ggccccggcc ccggccgcgc cggcccagga gacgccgctg aagatcagca cgaggggcac
     3961 cagggcgcag ctgaacgcgc cccagcgcac cacgtcactc actgggtcgg gtgatctgtc
     4021 ggacggcaac ggcaccgcgt actcccctcg gacgggctgc tactacaacg ccgccgacga
     4081 tcacgggtca ccgccagggg cgcgaggggt gcgtacgggg gcaggtcggg gcattgccat
     4141 ccgcgccacg ctccggcatg ctcccgggga acgttcgagg ccccacccac ctcgcacggg
     4201 cgccctgcgc ccatggcggg ctctgggcag cgggggagtg gcgccgtact cttggggtat
     4261 cgggttggga agatgattcc cagtcgtatc gttcctcttt gaactatggc tcccgcactt
     4321 cgggcgcgtc agctcagtca actgccggat caagtcaatc gccgttcccc gttcgcccct
     4381 ccgcaagagg acgtcctcgc cgagacacca atggccggtc acgaaatccc cgaacccgcg
     4441 aaccgcaagc aggtcgccga tcccatggcg gacctcgaag cggcggaaaa gacgcgccac
     4501 tcctgcgacc ccgcgttccg gcacggcgtc gtggtcggct tcgacggctc catgtcgagc
     4561 gagcgggcat tggcgtatgc aatcggtatg gcccggcgcc tcggctccgg tttgatcatc
     4621 gtccatgtgg ccaaccggct gccgacgacg gtctgggcgg gctgtgagcc cccggtcttc
     4681 gtggacgtgc cggatcaccg caccgaagtg ctcggcctgg agttggcctg cgccgatcac
     4741 ctcagcgagg tcccctggat cctcgtcgag cgcggtggcg acatctgcca tgagctggag
     4801 gaggtcggcc gggagtacga ggccgacgcg atcgtggtcg gttccacgca cggcatcgtg
     4861 ggccggatct tcggctcggt ggccgggcgg ctggcccgcc gggcgcagcg cccggtcatc
     4921 gtgattccct gacgcgcccc cctttgcgcc taagccggcg ccgctttcgc gcaggtggct
     4981 gggcgccgtg ggggggtgct caattgtcgc ttcggtggag ggggttgggg tggggtgggg
     5041 gagcgctcca ccgggctccc ccaccggggt gctactcgac cgtcacggac ttcgccaggt
     5101 tgcgcggctt gtcgatgtcg cggccgaggg ccaacgccgt gtggtaggcg agcagttgca
     5161 gcggaatgcc catcaggatc gggtccagct cgggctcgtt cttcgggacc aggatggtgt
     5221 ggtcggcctt ctcctgctcc tggtgggcga cggccaggat gcggccgctg cgggccttga
     5281 tctcctccag ggcggcgcgg ttcttctcca gcaggtcgtc gtccgggacg atcgcgacgg
     5341 tcggcatcgc gggctcgatc agggccagcg ggccgtgctt cagctccgac gccgggtagg
     5401 cctcggcgtg gatgtacgag acctccttga gcttcagcga ggcctcgcgg gccaccgggt
     5461 agccgcgcac ccggccgatg aacatcatcg acttggcgtc cgcgtaggcc gccgacagct
     5521 tcttgatgtc ctcctcgccc ttgaggatct cgtcgatctg cgcgggcagc ttgcgcaggc
     5581 cctcgatgat ccgcttgccg tccgcgaccg acaggtcacg gatccggccg aggtgcaggg
     5641 cgagcagcgc gaaggagacc accatgttgg tgaagcactt ggtggagacc acgcagacct
     5701 cggggcccgc gtgcacgtag atgccgccgt cggtctcccg ggcgatcgcc gagccgacca
     5761 cgttcaccag gccgagcacc cgggcgccct tgcgcttgag ctcctggacg gccgccagca
     5821 cgtcgtaggt ctcaccggac tgggagaccg ccacgtacag cgtgtcgggg tccacgaccg
     5881 ggttgcggta gcggaactcg gaggccggct cggcgtccga ggggatacgg gccagctcct
     5941 cgatcatctg cgcgccgatc tggcccgcgt ggtacgaggt gccgcagccc aggatcttga
     6001 cccggcgcac cccgcgcgcc gcgcgggcgt cgaggttcag gccgccgagg tgcacggtgg
     6061 agaagcggtc gtcgatccgg ccgcgcagcg cgcggtccac cgcgtccgcc tgctcggaga
     6121 tctccttgtg catgtacgtg tcgtggccgc ccaggtcgta cgactcggcc gcgtactcga
     6181 cggtctccgg agcggacgtg gtccgcgagc cctcggtggt gtacgtgcgg tagtcgtcgg
     6241 ccttgagggt ggccatctcg ccgtcgtcga gggtgacgac ctggcgggtg tgcgagacca
     6301 gcgcggcgac gtcggaggag acgaacatct cgtgctcgcc gatgccgagg acgaccgggg
     6361 agccgttgcg ggcgaccacg atccggtcgg ggaagtcggc gtgcagcacg gcgatgccgt
     6421 aggtgccctc gatgtgccgc agcgcctcgc ggaccttctc ctccagcttc tcggcggtgg
     6481 agcggccgat gaggtgggcc agcacctcgg tgtcggtctc ggaggcgaag acgatgccgt
     6541 cggcggtgag cttggcgcgc acgtccgcgg cgttgtcgat gatgccgttg tggacgaccg
     6601 cgaccttgcc ctcggtgtcc tggtgcgggt gcgcgttctc gtcggtcggc gcgccgtggg
     6661 tggcccagcg ggtgtgcgcg atgccggtgg agcccgcgaa gcgcttgggc agccgggact
     6721 ccagctcgcg gacccggccc ttggccttgg cggtcttcag gccgcccgcg gtgcccttgg
     6781 cgtggatcgc gatgcccgcg gagtcgtagc cgcggtactc cagccgctgc aggccctcga
     6841 tgagcagcgg ggcgacatca cgtttgccga tatacccaac gattccgcac atacagtgac
     6901 cctcccagaa agcgtggtaa cgatggttcg tgcccggccc ggtgccccgg gcgcggccgt
     6961 cagccgtaga tcaggcggcg cagctggcgg gtcgagagat cgggtggcgc cacggcgcgg
     7021 tgcggcatct cgtggcggat ccgttcgaag atcgcctcgt tgcgcagtcc ctgggactgc
     7081 agctcgcgat ggcgacggcg gacgaattcc tccgtggtct cgtcgaagta cgccagcacg
     7141 tccagcacca cccgggcggc ctcaccgcgc tgcagcggtg tgctgcgcac caggtggtcc
     7201 accaggtctt cgtgcggcgc ttcagcgctg cggtgacggc gttcgagcac ccgtagatac
     7261 tgcggggcgg cgcgaagaat cgcaagaaat ctgcccgata gcgggcaggt ccccggtttg
     7321 gcggctggaa agtggtctga accttgaccg gaatcaaggc tcacggtacg catggtcacg
     7381 tttcggtcgc tccatgccat gcaccacgcc atgcacgagg ttcgccgaag ggaccgtcga
     7441 tgagacgacg cagactgctg ttctcgctgc tgctggtcgc ggcggcgggg ctggggaccg
     7501 ccgccgtacc gccaccgggc gccgcggggg ccgctccccg ggccgccacc ccgctggacc
     7561 gggtgatccc cgcgcccgcc tccgtacgcg gcggcgggga cgcgtacacc ctcggtgacc
     7621 gcacccggat ccgggtgccc ggcggctccg gggaggccaa gcggatcgcc ggctatctgg
     7681 cggggctgct gcggcccgcc accggactcg ccctccccgt caccaccaag gacggccggg
     7741 acggcatcgt cctccggctc ggcggcagcg gtaccggcgg gctgggcgcc gagggctacc
     7801 ggctgacctc cgacggccgt gcggtcaccc tcagcgccgc ccgcccggcc ggcctcttcc
     7861 acgccgtcca gacgctgcgc cagctgctgc ccgccgacgc ggagcggcag cgcgcccggc
     7921 gcgggccctg gcggatcgcc ggcggcacca tcaccgactc cccgcgctac ggctaccggg
     7981 gcgcgatgct cgatgtctcc cggcacttct tcaccgtggc gcaggtcaag cggtatatcg
     8041 accagctcgc gatgtacaag atcaaccggc tgcatctgca tctctcggac gaccagggct
     8101 ggcggctcgc catcaagtcc tggccgcggc tggcgacgta cggcggctcc acccaggtcg
     8161 gcggcggccg cggcggctac tacacccagg acgactaccg cgagatcatc cgctatgccg
     8221 cgtcccgcta tctgaccgtc gtccccgaga tcgacatgcc gggccacacc aacgccgcgc
     8281 tggcctcgta cgcgccgctc aactgcaacg gccaggcacc gccgctctac acgggcaccg
     8341 aggtcggctt cagctccctg tgtgtgccga agcgggagac ctacgacttc gtggacgatg
     8401 tcatccggga gctggcggcc ctgacgcccg gccgctacct ccacatcggc ggcgacgagg
     8461 cgcactccac cagccatgcg gactatgtgg ccttcatgga caaggtgcag ccggtggtcg
     8521 ccaagtacgg caagaccgtg gtcggctggc accagctgac cggcgcgcac ccggccaagg
     8581 gcgccgccgc gcagtactgg ggctacgaca agacgggcgc ggcggagcgg cagcaggtcg
     8641 ccgacgccgc ccggaacggc acccggctga tcctctcgcc cgccgaccgc gcctacctcg
     8701 acatgaagta cgacaaggac acgccgctgg gcctgtcctg ggccggctat gtcgacacca
     8761 ggcgctccta cgactgggac ccgggcagct acctccaggg cgcgcccgcg ggctcgattc
     8821 tcggcgtcga ggccccattg tggacggaga ccctcaagac ctccgcggac atcgagtaca
     8881 tggccttccc gcggctgccc ggcatcgcgg agctgggctg gtccccggcg agcagccacg
     8941 actgggacga ctacaaggtg cggctggccg cccaggggcc gcgctgggac gcgctgggca
     9001 tgaactacca ccgcgcaccg gaggtgccct ggcccgcgcg gtgagacggc cgtgccgggc
     9061 gtcctcggac gcccggcacg gtctcccggt cctcagaccc ggtcggcggc gatcagcaga
     9121 tactggaagc tgccgttgcg gtacgcggtc aggaaggtgt cctcgatccc cgtgaccagg
     9181 tggtcggcct cccggcgcaa ctcccagtac gggagcgcgg cttcggtgag atcctcgacg
     9241 tgcacgggga ccagccggtt gcgggccatc gcgcggaagt actccgatcg cgggtggata
     9301 tcgcagatgt agtgggcgtt gatcagcgac acctcgcggg aggcccgccc gtaggtgtcg
     9361 ttgtagcagc cggtgatcgt gacataccgt ccaccgcgcc gcagcagccg cgcgtgctcg
     9421 gcgaacagca ggtccagctc gacatacatg ctggactcgt tgttccagga cgccgcgtac
     9481 gcccccgagg tgaagccggt gtcgagcata ttgcggtggt ggtagcgcac cttgtcgtcg
     9541 ataccgcgct tacgggcctg cgcgttggcg aagtcggcct gcttggcgga gatcgtggcc
     9601 ccgtcggtgt gacagccgtg ccgcagatgc gcgaccacgc tgccgccgcc gcggccgcac
     9661 ccggcgtcga agacccggtc ggtgggggag aggtcgccga ggcgggaggc gagcagctcg
     9721 gcctgggcgt gttccagccg gtgcagttcg ccggtgatcc gctcccggcg ccggacgggg
     9781 tccggctcgt tcagcaccga ccggtcggcc tccccgatgc cgtagtggtg gtggtacagg
     9841 tcgtcgatct tgccgagttc gaggttgacc gggttttcct cggcgttcca gtagtccgcg
     9901 acccgggact ggtacgtgga ctgggtcggc accggtgtgc gggcggtgtc ggcgtgagcg
     9961 atggacaacg gtggctcctt gctgtgctgc gcggatcggt ctaccagtaa tggggcaggt
    10021 ggtagcggtc ggtgttggtg gcgtgccact cgtggttgcc ggacacccag tcggcgaggc
    10081 cccggacata ccgttcgagg aggggggaga gggcggccag cggggccgac tccgtctcga
    10141 acgcctccat gacccggttg tggatctcga cgctcttcag gtaggcggcc ttcagaccgc
    10201 gcttgtcgtt ggcggccacc acctggggca ggttcagatg gtccgggtca ctcgccagct
    10261 ccttggtgaa ggagtacagg tcgttgacga tggtggtggc gttgcaggcc agcgcggtga
    10321 cccgctggac ctcggggcgg gcgtagagcg cctcgggcag ttcgtagccg tccacggcgt
    10381 cgacgatcga cagacacgga cggaagttgt tgaactgccg catgaccagg tactcccaga
    10441 cccgcggcgc atgccgggtc tccgcccagg cggcctcggc gagatagccg aggtgcagcc
    10501 gggcgatgtc ctggacgaag cggtctgcct ggctgggggt ggcgagcgcc gcgtagtcct
    10561 tcagggccca gtggtaggaa cgcagcgggc cgtcggcctg cacgccctgg cgccactccg
    10621 cctccagttc gggggtgccg tggaacgggt cgagggccga ctgggccatg atcagccggc
    10681 cgcccaggcc acggtgcgcg ccgcccttgc cctcgtcctc ctcgcagtag caggtgtcga
    10741 cgatgttctc ggccagcagc agcttgcccg cgacggtgag gcggtcgagg tcggccgccc
    10801 cgggatgctg cagtgcgacc gcccgcccga actggaactg ggtgaagtcc ccgctccact
    10861 gcgcggggaa cagatccagc tgacgggccc aggtctccag cctgcggtcg acctccgcgg
    10921 ccgtttcggg gtcggcgggg gcggcgggcc ggtatctcag cccggggacg gctccgccgg
    10981 ggcgccgggt gcgcagggtc cgggcgaggt tcggcgggcc gggcagcgca tacgcggcgg
    11041 cggggttcgg gggcgtgctc atggttcggg actccacctg gtcagtcggc gctccggccg
    11101 gtctggacgt tctccaggac tccgacggcg tcgggcacga ggatggccag tgagtagtag
    11161 gcggtgacga ggtagctgat gacggcggcc gggtcgatgc ccatgaaccg gacgttcagg
    11221 ccgggttggt actcctcggg gatgccggtc tggtgcagac cgaccactcc ctggtccgcc
    11281 tcgccggtac gcagcgcgag gatgctgctg gtctgtgtgt cgctgatcgg gatcttgccg
    11341 caggggtaga tcgggacgcc gcgccaggcg ggcacctcgt gcccgtcgac ggtcgccgtg
    11401 cccggcacca gaccgcgctt gttgcactgc cggaagaagg cggcgatcgc cttcgggtgg
    11461 gccaggaaca gccgggtctt gcggcgcatg gacagcagct cgtccatgtc gtcgggggtg
    11521 ggcgggccgg tgtaggtgct gatgcgatgg ccgtagtcgg cgttgtgcag caggccgaac
    11581 tcccggttgt tgaccagctc ccactcctgg cgctcgcgga tctcctcgac ggtgagccgg
    11641 agttgctgct gggtctggtc catcgggtcg ttgtagaggt cggcgacccg gctgtggacc
    11701 cgcagcacgg tctgggtcag cgagagctcg tactcgcgcg gggcgaggtc gtagtcgacg
    11761 aagccgctcg acagcgtcgg ctcgccgacg tgccccgccc gcaccggcac ctccgcctcg
    11821 cccttgcggt tcatcgggcg ctgctgccgc tccgcgtacg ccgacagatg ggcggccagg
    11881 gacggcgccc ggtcggtgaa ctcccggacc acgtcccagg gcagcgccat cacgacgccg
    11941 gccgtttcgg cccggaccga gctcagccac cgggggtcgg gccggccgat cgcctcgtcc
    12001 cccatctggt cgccgtccgt gacgacgccg atgacctcct cctcgccgta cttgccgacc
    12061 gtgtagcggg cgaaacggcc gtgtacgacg aggtacgcct cggtggtggg ctgcccggcc
    12121 tcgaacagga cctggccggc ccggacctcc cgcacccgga agcggccggc gagttccttg
    12181 aggacctcgg tgtcggagta gccgcgcagg gccgggagtt cggtgagcgt ctgcgggatc
    12241 acccggatgt cgtccgcgcc gttctgctcg aactggaccc gaccccggcc gacacggagc
    12301 tgcagccgcc ggttgacccg gtaggcgccg cccttgacgt ccacccaggg cagcgtcttc
    12361 agcagccatc gggaggtgat ggcctgcatc tggggctcgg acttggtggt ggtcgccagc
    12421 tggcgcgcgg cctgggtgct gaggctggtg agcgcgctgt cggcgggtgc tgcgagcgcg
    12481 ggctcgtcgg aggtggaacc ggtgacgctg tccggtacgg acactttccc tcccgggaca
    12541 tgaacagacg tgagcagaac ggccgctgat gatcaaagtg gccgtgtgca ggagcaagcc
    12601 aaacaggagg gagcgcgcgc cggtacggcg tgaaaggggg cggcttcgca gccggacgtc
    12661 ataaaccccg gagcgatgca tacggatcat ggttgtgcgc ccgcgcgccc ttgggccagg
    12721 gcatgctccg tacgcacggg ggtatgggcg cggccgcgca cgggcgctcc aggggagccc
    12781 gctgtcaccc cgtacaccac agtggcggcc cggtcaccga agcgaccgga ccgccacatc
    12841 cacttctccg cgcagcgcct acccgacgcc caactcccgg gcgatcagca tccgctggac
    12901 ctcgctggtg ccctcgccga tctccaggat cttggcgtcc cgccacatcc gggcgaccgg
    12961 gtactcgttc atgaagccgt agccgccgtg gatctgggtg gcctcacggg cgttgtccac
    13021 cgcgatctcg gacgagtaga gcttggccag cgcggcctcc ttcttgaacg gttcgccgtg
    13081 caccagccgg gaggcggcat cgcgccaggc cagccgggag gtgtgggcgc gcatctccat
    13141 gtcggcgagc ttgaactgga tcgcctggtt gctgccgatc gcgcggccga aggcccgccg
    13201 ctccttggcg tagcgcacgg actcgtccac acagccctgc gccaggccgg tggccagcgc
    13261 cgcgatggcg atccggccct cgtcgaggat gcgcaggaac tgggcgtagc cgcggccctc
    13321 ctcgcccagc aggttggcgg ccgggacccg gacgcctgcg aacgacagct cgcgggtgtc
    13381 cgaggcgctc cagccgacct tggagtacgg ggcgccgacc gtgaagcccg gggtgccgga
    13441 gggcacgatg atcgaggaga tcagcgggga gccgtcgtct ttgcggccgg tgacggcggt
    13501 gaccgtgacc agcccggtga tgtccgtacc ggagttggtg atgaagcact tgctgccatt
    13561 gatcacccag tccccgccgt cccgtacggc ggtcgtccgg gtcgcgcccg cgtccgagcc
    13621 gccgtccggt tcggtgaggc cgaaggcgcc gagcatctcc ccgctgcaca gcttgggcag
    13681 ccaggcgcgc ttctgctcct ccgtgccgaa gtggtagacg ggcatggcgc ccagggagac
    13741 gcccgcctcc agggtgatgg ccaccgagga gtcgacccgg gccagctcct ccagggcgat
    13801 accgagggcg aggtagtcgc cgcccatccc gccgtactcc tcggggaagg gcagcccgaa
    13861 caggcccatc cggcccattt cctgcacgat ctcgtacggg aacgcatgct gctcgtagta
    13921 ctcgccgatc ttcggggcga cgacgtcgtg cgcgaacgcc tcgactgtgc gccggagttc
    13981 ttccagctcg gcggaaagac ggtggtccag ggacatgggg gtcactcctt gtgggagagg
    14041 gcacggaggg ttcgggaggg gctcggccgg cccagggcct cggccatcca cacactggtg
    14101 gcggtcaggc ggtccaggtc gaccccggtc tcgatgccga ggccgtgcag catccacacg
    14161 aggtcttcgg tggcgaggtt tccggtggcg ctcttggcat acgggcagcc gccgaggccg
    14221 cccgccgagg cgtcgacggt ggtgacgccg tgctggagcg cggcgaaggt gttggcgagg
    14281 gcctgcccgt aggtgtcgtg gaagtgcacc ccgatacggg aggtgggcac cccggcctca
    14341 ttgagggcgg ccagcagggt ctgcacatga ccgggggtgg ccaccccgat ggtgtcgccc
    14401 aggctcagtt cgtcgcagcc cagatcgagc agctcccggc agacccggac ggtctgcgcg
    14461 acgggcaccg ggccctccca ggggtcgccg aagcacatcg agagatagcc gcggacgtgc
    14521 acctcggcgt ccttggcccg cgcgatcacc ggggcgaaca tcgccagcgc ctcgtcgacc
    14581 gtgcggttga ggttggcctt ggcgaacgac tcggtggcgc tgccgaacac cgcgatccgg
    14641 cgggcgccca gggcgagcgc ccggtccagc ccgcgctcgt tggggaccag caccgggagc
    14701 cggtgcggat ccagatcggc cagcagcggg aacagctgct cggcgtcggc gagttggggc
    14761 acccacttgg ggtggacgaa gctggtggcc tccaccgtcg gcaggcccgc ggcggcgagc
    14821 cggtggatga actccgcctt gatctccgtg ggcaccacgg tccgctcgtt ctgcaggccg
    14881 tcgcgcgcgc cgacctcatg gatccgtacc cgggtgggca ggccctccgc gcggatctcc
    14941 atcggcagtc cggccgcggt catcaggcgc tctcctgccc gccctcgggg gcgcccgcgg
    15001 acgcggcggg ctcctcgggg ctctcgtgcg gggcgaccac ggccaggatc tggtccatgg
    15061 cgacggtcga gcccgcggtg acgtcgagtt cggcgacggt cccggcgtgc ggtgcggaga
    15121 tgacgtgctc catcttcatc gcctccacca ccaacaggcc ctgaccggcg gccacttcgt
    15181 cgccgacggc gaccttgacg acggtgacgg tgccgggcat cggggcggcc agggtgtccg
    15241 cgccgtgcgc cccggcggcc ccgcgcagcg ccgcggccac cgggtcgtgg gtggtgacct
    15301 gccaggagtc gccgtcccgg ccgagccagt cgccgctgtg gtggaaggtg tgcagcacgc
    15361 cgtcgacggt gacccgtacg cggtccggtg tgacctgggc ggcggccgcg tccgggcgga
    15421 cgtcgtgggc caccgggtcg tgtcccggca cccgcagcca gtggcgtacg ggcgcgggct
    15481 cgccgccgag ccggaagccg ttcggcgcgg cgaacgggtc gcgccagccg ccgtcggcca
    15541 ccgccggttc cagggcggcc tgccgcaccg ccgcggccgc cgcgtacacc tcgtccggca
    15601 cggtgccgtc gaccagaccg gccgcctccc gctccaccag accggtgtcc agctcgccgg
    15661 agaccacgtc cgggtgggcc agcagccgcc gcaggaaacc ggcgttggtg gtgacgccga
    15721 gggtgaccgt cccggccagc gcggcccgca gccggcgcag cgcgctcgcc cggtccgggc
    15781 cgtgggcgat caccttggac agcatcgggt cgtagcggct gccgacctcg ccgccctcgg
    15841 agagcccgga gtcggtgcgc accccgccgc cctccggctc atggagcgtg agcaccgtgc
    15901 cgccggtcgg caggaagtcg cgggccgggt cctcggcgca gatccgcgcc tcgatggcgt
    15961 gtccggtgag ggtgatgtcc tcctgggcgt acgggagccg ctcaccggcc gcgacccgca
    16021 gctgccactc caccaggtcg agaccggtga ccagctcggt gaccgggtgt tccacctgga
    16081 ggcgggtgtt catctccatg aagtagtagg aggccgggtc cttgcccggg acgatgaact
    16141 cgacggtgcc ggcgccgcgg tagccgcagg agcgggccgc cgacgccgca gcctcgccca
    16201 tcgcggcgcg ggtggcctcg tccagcagga ccgagggggc ctcctcgatg accttctggt
    16261 ggcggcgctg gagggagcac tcgcgctcgc cgaggtggat gacgttgccg tggccgtccg
    16321 ccagcacctg gatctcgatg tgccggggcc ggtcgatcca gcgctcgacg agcagcgtgt
    16381 catcgccgaa ggaggagcgg gcctcgcggc gcgcggaggc gatctcgtcg gccagcagcg
    16441 cctcctcgcg caccagccgc atgcccttgc cgccgccgcc cgcggacggc ttgagcagca
    16501 ccggcatgcc gatctcccgg gccgcggcgg ccagttgacc gtcgtccagc ccgctgcccg
    16561 aggagccggg gacgaccggg acgccggcct cccggaccgt ctccttggcc cggatcttgt
    16621 cgcccatcag ctcgatggcg tcggcggacg ggccgatgaa gaccagcccg gcgtccgcgc
    16681 aggcacgggc gaaggcggcg ttctcggcga ggaagccgta gcccgggtgg accgcctggg
    16741 cgccggtccg gaccgccgcc tccagcagcc gctccacgga cagatagctc tcggcggccg
    16801 ctgccggacc gatccgtacg gccgtgtcgg cctcgcggac atggcgggcg tcggcgtccg
    16861 catcgctgta cacggcggcc gagcggatgc cgagggcgcg cagcgtacgg atgacacgga
    16921 ccgcgatctc gccgcggttg gcgatgagca cggtgtcgaa attggtggcc attgctgggg
    16981 acatccctct cacatccgga agacgccgta gccgggcgcg gtgctgtcct tctggggaag
    17041 cggtgcgttg gcacaggccg tcagcgccag ccccagcacc tgccgggtct ccagcgggtc
    17101 gatcaccccg tcgtcccaca gccgcgcggt cgcgtagtag gcgttgccct gggtctcgta
    17161 ctgctcgcgg accggcgcct tgaaggcggc ctcctcctcg gcgctccact cctcgccatg
    17221 cgcctccaac tggtcgcgct tgacggtcgc caggacggac gcggcctgtt cgccgcccat
    17281 cacggagatc ttggcgttcg gccacatcca caggaagcgc ggcgaatagg cccgcccgca
    17341 catggagtag ttgcccgccc cgtaggagcc gccgatgacg accgtcagct tgggcacgcg
    17401 ggtgcaggcc accgccgtca ccatcttcgc gccgtgcttg gcgatcccgc cggcctcgta
    17461 cgaacgcccc accatgaagc cggagatgtt ctgcaggaac agcagcggga taccgcgctg
    17521 gtcgcacagc tcgatgaagt gggcgccctt ctgggcggat tcggagaaca ggatgccgtt
    17581 gttggcgacg atgccgaccg ggtggccgtg gaggtgggcg aagccggtga ccagcgtcgt
    17641 gccgtactcc gccttgaact cggcgaagcg cgagccgtcc accagccggg cgatcacctc
    17701 gcggacgtcg tagggcgtac gcgagtccgc gggcaccgcc ccgtacagcc cggccgggtc
    17761 caccttgggt tcctcgacgg tccgtacggt ccacgggagc ggctcgcgct cgccgagggt
    17821 gccgacgatg gtgcgcacca gacgcagcgc atgggcgtcg tcctcggcga gatggtcggt
    17881 gaccccggag gtcttcgcat gcacctcgcc gccgcccagc tcctcggccg tgaccacctc
    17941 acctgtggcg gccttcacca gcggcggccc gcccaggaag atcgtgccct ggttgcggac
    18001 gatcacggcc tcgtcgctca tggccgggac gtacgcgccg cccgccgtgc aggagccgag
    18061 gaccgcggcg atctgcggaa tccccgcacc cgacatccgc gcctggttgt agaagatccg
    18121 cccgaagtgc tcccggtcgg gaaagacctc gtcctgcatc ggcaggaagg cgccgccgga
    18181 gtccacgagg taaagacagg ggagacggtt ctccagggcg atctcctgcg cccgcagatg
    18241 cttcttgacc gtcatcgggt agtacgtgcc gcccttgacc gtggcgtcat tggcgacgat
    18301 caccgtctcg cggccggaga cccggccgat cccggcgatc accccggcgg ccggtgcggc
    18361 cccgccgtac atcccgtccg cggccagcgg cgccacctcc aggaacggcg agccggggtc
    18421 cagcagggcg tccacccggt cccggggcag cagtttgccg cgggcggtgt gccgcgccct
    18481 ggccttctcg ccgccgccca gccgggccgc ggcgagcttc tcgcgcagct cggcggccag
    18541 ctcgcggtgc gcggcctcat tggcccgcca ggagtcggac gccggatcgt cccccacgct
    18601 cgactgcgct cgcgcggggg gacccccatc actccccagc accggtgcct gctccatcag
    18661 tacgagctcc cttgctcggt ctgctgtccc gccgccgcgg tccgcggctg ccgggccatc
    18721 cgggttaatg ggcgttaaca acatctgcct tcaggttaac gagcactaac ccgactgtct
    18781 acaatcgacg gcatgagtaa tgcgcagtcc tccgccccga ccagccgccg cgagcagatc
    18841 ctcaaggagg ccgcccggct cttcgcggag cgcggcttcc acggcgtcgg tgtggacgag
    18901 ataggggcgg ccgtgggcat ctccggcccg gggctctacc ggcacttcgc cggcaaggac
    18961 gcgatgctcg ccgagctgct cgtcgggatc agcgagcggc tgctcgcggg cggccggatg
    19021 cgggtcacgg agggcggcgg gagccccgag gcggtgctgg acgcgctgat cgacgggcat
    19081 atcgacttcg cgctggacga ccggccgctg atcaccctgc acgaccggga gctggaccgg
    19141 ctgcgggagg ccgaccgcaa gcgggtccgc cagctccagc ggcagtatgt ggagctgtgg
    19201 gtggaggtcg tccgggaggc gtatcccgtg tgtgtggagg ccgaggcccg gtccgcggtg
    19261 cacgccgtct tcggcctgct caactccacc cctcacctgg gccgccccgg cgccctcccg
    19321 ggccgtacgg aaatggcgga actgctgcac cgcctcgcgc tgggcgcttt cggcgcggtg
    19381 gccggggagc cgtcggcggg ggagtcgatg gcggcggcgg tgccgggcgc gtagtggccc
    19441 cctgcctcgc acgggttttc gttgacctct ggacagcttg ggtaactggc cggtagcttt
    19501 cgctgagcaa gcgcttagcc atgcgcttgg gccggcgacc tgaaggaggc gacgtagcaa
    19561 tgcgccgcac ggtgttcaac gaggatcacg aggcgttccg cgcgaccata cgcgccttca
    19621 tcgaggccga ggtcgtgccc gtgtacgacg agtggctcgc cgccggccag gccccgcgcg
    19681 acttctacta caagctcggt gagctgggcg tcttcggtat ccgggtcccc gaggagttcg
    19741 gcggcgccgg tatcgagtcg cacaagttcg aggccgtgat gtacgaggag acctcccgcg
    19801 cgggcgtctc cttcggcggc tccggtgtgc acgtcctgct cggtctgccg tacatcgaga
    19861 tgctcgccac cgacgagcag aagaagcgtt tcctgccgaa gttcgtcacc ggcgaggaga
    19921 tgtgggcgct ggcgatgacc gagccgggca ccggctccga cctcgccggc atgaagacca
    19981 ccgcgaagct gtccgacgac ggcacgcact acgtcctcaa cggcgccaag accttcatca
    20041 ccggcggtgt gcacgccgac cgtgtcatcg tctgcgcccg caccgccgcg ccccgcgagg
    20101 acgaccgccg cttcggcatc tcgctcttcg ccgtggacac caaggccgag ggctactccg
    20161 tcgggcgcaa gctggacaag ctcggcctga agacgtccga caccgccgaa ctggccttcg
    20221 tcgacgtcaa ggtcccggtc gaggacctgc tgggcgagga gaacaagggc ttcggctacc
    20281 tgggcctgaa tctcgcctcc gagcgctggg gcatcgcctt cggcgcgtac gcccaggcca
    20341 aggccgccgt ccggttcgcc aaggagtacg tgcaggagcg cacggtcttc ggcaagcccg
    20401 tcgccgcctt ccagaacacc aagttcgaac tggccgcctg ccaggccgag gtggacgccg
    20461 ccgaggccgt cgcggaccgc gcgctggagg ccctggacgc cggtgagctg agcccggccg
    20521 aggccgcctc cgccaagctg ttctgcaccg aggtcgcgca ccgcgtgatc gacaagtgcc
    20581 tccagctgca cggcggttac ggcttcatga acgagtaccc gatcgcccgc ctgtacgccg
    20641 acaaccgcgt caaccgcatc tacggcggca ccagcgaggt catgaagatg atcatcgcca
    20701 agtccatggg cctctagccc ctaagggccg cacgcacgtg aacgacgccc tgcgctccct
    20761 gctcgatctg ctcgccctgg agcggatcga gcaggacatc ttccgcggcg agagccgcgc
    20821 ctcggtcgtg ccccgggtct tcggcggcca ggtcgccgcc caggccctgg tcgcggccgg
    20881 gcgcacggtc cccgccgacc gttccccaag ttctcggctc cgctcgaaca ggggaggccc
    20941 cattccgcac tccctgcacg cgtacttcct gcgccccgga gaccccggcg cgcccatcgt
    21001 ctacaccgtc gaccgcatcc gcgacggccg ctccttcacc acccgccggg tcgtcgccgt
    21061 cc
//
