LOCUS       NZ_CP114205            22250 bp    DNA     linear   CON 09-NOV-2024
DEFINITION  Streptomyces tubercidicus strain DSM 40261 chromosome, complete
            genome.
ACCESSION   NZ_CP114205
VERSION     NZ_CP114205.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces tubercidicus
  ORGANISM  Streptomyces tubercidicus
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8284047)
  AUTHORS   Ruckert,C., Busche,T., Kalinowski,J. and Wittmann,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-DEC-2022) CeBiTec, Bielefeld University, Sequenz 1,
            Bielefeld, NRW 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 02-MAR-2022
            Assembly Method                   :: flye v. 2.9; Newbler v. 2.8
            Assembly Name                     :: DSM40261_v1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 133.7x
            Sequencing Technology :: Oxford Nanopore GridION; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/09/2024 02:53:13
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,167
            CDSs (total)                      :: 7,077
            Genes (coding)                    :: 6,906
            CDSs (with protein)               :: 6,906
            Genes (RNA)                       :: 90
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 171
            CDSs (without protein)            :: 171
            Pseudo Genes (ambiguous residues) :: 0 of 171
            Pseudo Genes (frameshifted)       :: 72 of 171
            Pseudo Genes (incomplete)         :: 133 of 171
            Pseudo Genes (internal stop)      :: 9 of 171
            Pseudo Genes (multiple problems)  :: 41 of 171
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 18:04:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3761492
            Orig. end                         :: 3783742
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP114205.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from DSM 40261.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22250
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="18"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22250
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22250
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12250](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12250)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            98..535
                     /db_xref="GeneID:96284129"
                     /locus_tag="STRTU_RS16230"
                     /old_locus_tag="STRTU_003245"
     CDS             98..535
                     /codon_start=1
                     /db_xref="GeneID:96284129"
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STRTU_RS16230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STRTU_003245"
                     /product="hypothetical protein"
                     /protein_id="WP_159744167.1"
                     /transl_table=11
                     /translation="MHAQAVRTHGTLTSATGTGRVGFIDAEDIAAVAAHALADSPLPGH
                     DLVLTGPEALTYDDIATTLTELTGRPVRHHPVTRDQLRDHLATAMPTEFATLLANLDHD
                     LAHGAGSHLTDTVERVTGHPPLNFRTHAERWYRDNRPRRGA"
     gene            complement(583..1056)
                     /db_xref="GeneID:96284130"
                     /locus_tag="STRTU_RS16235"
                     /old_locus_tag="STRTU_003246"
     CDS             complement(583..1056)
                     /codon_start=1
                     /db_xref="GeneID:96284130"
                     /inference="COORDINATES: protein motif:HMM:NF040152.3"
                     /locus_tag="STRTU_RS16235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_003246"
                     /product="Pycsar system effector family protein"
                     /protein_id="WP_159744168.1"
                     /transl_table=11
                     /translation="MERFLAANGVEIARADTKAAVLLGFMGAVLGAFITVTRGSASGQA
                     AASWKADVLWWGAVVTALLAIVCFVSAIAPRRRRGRERGVAAPGYFEHIGRGEDGDVLS
                     HAFARLAHDPTGPLLASVRRTSEIIRSKYRWIEMGTALLLVALPQFAAALQPG"
     misc_feature    complement(595..597)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(1239..2216)
                     /db_xref="GeneID:96284131"
                     /locus_tag="STRTU_RS16240"
                     /old_locus_tag="STRTU_003247"
     CDS             complement(1239..2216)
                     /codon_start=1
                     /db_xref="GeneID:96284131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014143696.1"
                     /locus_tag="STRTU_RS16240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_003247"
                     /product="hypothetical protein"
                     /protein_id="WP_174878877.1"
                     /transl_table=11
                     /translation="MTTDTSQPVYTLAAHAPWREILRHRWSGRLDRALVLRDHSGAYRV
                     LGSRNRYGAPHGEIGAPEVAALASSAPKLLGGYDSAFHVQLHEQSGTRSVGLPTAYGTE
                     SVDVRVLWWVHDPVEVVRSRTSYGWDAVRKDLDRRLRHLEDAYAADGQSIGAPEIMQEL
                     AVPQELAGFGLTYRVTDICGQESEGELRLGQPGGIGLPYSWTTPRREEYAFCTDAVRNG
                     PVALAALWLHRHPDQVSQVLDWAVNHRSLLKEETNWQDQVAGLLGKLTDEEQQELSELL
                     RDRLLRLGRPVPAQPAPQESPGGKGPGRPAANGWPRGTAKEWSV"
     gene            complement(2213..4519)
                     /db_xref="GeneID:96284132"
                     /locus_tag="STRTU_RS16245"
                     /old_locus_tag="STRTU_003248"
     CDS             complement(2213..4519)
                     /codon_start=1
                     /db_xref="GeneID:96284132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014143695.1"
                     /locus_tag="STRTU_RS16245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_003248"
                     /product="hypothetical protein"
                     /protein_id="WP_246240626.1"
                     /transl_table=11
                     /translation="MSAEDARPALPRGTDGTTREEPEAPAAGGEPPEGDIGFADPDDGD
                     FDETAAEFDAAAAEFALHGGEFAGPPFAGRPFGGQPHSVIFAPGANINNGSVHGGQRVE
                     NGGAATGTGTGGRRVEAHEGPISAIEILDAQAGFAEPDWFPEALAELDSRLLFLTGEPG
                     TGRRTAALNLLSRHSGGSMSLRAVDGDMNLASWRPGHRDTRGYLVDGLLPDYPLKPGMV
                     RHLQSLLSTADARMVVVLPDAPELVRRLSRDLHVTPVRCAPPPARAVFDARFKHAVPDP
                     SERARRLAALEPGLLDELLAPELVPAQVAELVAAVAAAEDGGPDLADLQKRLSFLAEGE
                     VPDLLAQLRDDADGLAFLLATCVFEGLDHRIVREEAERLLALADGRLSSVLPEGADDSG
                     EDGRRERERTPRPNPQFVFRRSLDELLRSVRAERSASEIHSNPGYTYAVEAVRFTRHRQ
                     AEAVLRHVWREYGHLSGLLTEWMADLRNEQELTEPVGRVMGRAAGWGGGRRALQHIRTL
                     AESNRRTSRTIAAYALGMAAEDPVLAREVKYRLSLWSAQQSWQVRSTVAYTCGADFGAA
                     RPELAMRLLRNVPRGLSDEHERTVDRAVRDALRDLFASGSQATVFRHLAEWADREGTLG
                     DVALRTFPRLLQNTSWCQEQLVDDGEYAPQIIDLVHRTLNDEELFAATCNAVLWWCRMA
                     TWGDLPRTAVETLLTALAADVRHGVFRLFVTIDRADDPDLAGLSIVRDALNTWRHGEPP
                     RHPANGSTHLNGSTS"
     gene            complement(4516..5538)
                     /db_xref="GeneID:96284133"
                     /locus_tag="STRTU_RS16250"
                     /old_locus_tag="STRTU_003249"
     CDS             complement(4516..5538)
                     /codon_start=1
                     /db_xref="GeneID:96284133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014143694.1"
                     /locus_tag="STRTU_RS16250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_003249"
                     /product="hypothetical protein"
                     /protein_id="WP_159744169.1"
                     /transl_table=11
                     /translation="MSPSRRPDLPEASAQPYSRSRPLPPYRGIVAVDAKDFTGYPAIEH
                     GEISRAIPQLLQTSFERAGIAEVWAERRFPGSTGDGYVFGFDPAKMPFVIHPWLSTLQE
                     VLTEFHVHSTGAVRIRLRVSLHIGPLPDAGEEYDGNGTPRNDTHRLLDSRPVKAMLAAS
                     SANITHVAAILSDRCYQDAVVSGYTGRHPDHFFQVPATVEGKQFEQAAWLYVPAPSGNL
                     YDRRILGDRVIEDHESGRGERGAESRGAGRRAAAPQVRIRADKGNVNNGTVYGGQSVRN
                     VESGGVGGDYTGGDSIGSVGGDYVRGDRFGGDYVGGNKAGTVHGNQGDTVHGDKREDRR
                     "
     gene            complement(5717..6412)
                     /db_xref="GeneID:96284134"
                     /locus_tag="STRTU_RS16255"
                     /old_locus_tag="STRTU_003250"
     CDS             complement(5717..6412)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0030552 - cAMP binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96284134"
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014143693.1"
                     /locus_tag="STRTU_RS16255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_003250"
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="WP_246240628.1"
                     /transl_table=11
                     /translation="MGDRVGGAAVPAGRTLRHFVGDAAWRDLLGQVFERRHPAGSMMLR
                     QGEPGTHVLAVLSGVAKVLRRERSGDLTLLAFRGPGELLGEVAVLDDDVRSASVETISS
                     CTVGVIGKAEFLRFVVAHDLFPVLMRYAFTRMRESDEARGGGGSTLTRLAATLVGLADI
                     SGHPASRPGEPLELALTRHELAQYLGVSRNTITATLAGLESCEVQAGRKRIVIGDLTAL
                     RRVAAAPGE"
     gene            complement(6598..7389)
                     /db_xref="GeneID:96284135"
                     /locus_tag="STRTU_RS16260"
                     /old_locus_tag="STRTU_003251"
     CDS             complement(6598..7389)
                     /codon_start=1
                     /db_xref="GeneID:96284135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089897.1"
                     /locus_tag="STRTU_RS16260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_003251"
                     /product="chitin-binding protein"
                     /protein_id="WP_159744170.1"
                     /transl_table=11
                     /translation="MRRKIAFLGALALTGGLVAFAPSGAHAVTGVITFHTRPENRPHEI
                     LDPGDDHCYGVGDGYGEVDNDTPTDLVLYTGRDCTGSVVVVVPARGWRNAKFGSLQLSA
                     NGPREPVPSADEDRRADEDGRADEDRRADEDRRADEDRPSDDDRSDNPDRSDDPDRSDD
                     RDPVNDRDSADDRDPVNDRDSADNDRPNRSDAADTSNRRDPSGPSDPSDDLDHSDHPGD
                     ARSTGSPQNRKRPTHAASPLDPVNAGSPGRPGRHGRPGAAG"
     gene            complement(7630..9750)
                     /db_xref="GeneID:96284136"
                     /locus_tag="STRTU_RS16265"
                     /old_locus_tag="STRTU_003252"
     CDS             complement(7630..9750)
                     /EC_number="3.6.4.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96284136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003981083.1"
                     /locus_tag="STRTU_RS16265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_003252"
                     /product="nuclease-related domain-containing DEAD/DEAH box
                     helicase"
                     /protein_id="WP_159744171.1"
                     /transl_table=11
                     /translation="MAAGSAVGRSAGASAARRAQQARRQERLLREQWQAARQRAERWEA
                     ASEGEQRVAAQLLMLTERGWRLLVDRRWPGTRAANVDMLLIGPGGVFVIDVKNWRAAPE
                     ISGGRLRAGGFSRDEHRRKLLAVTKAAESAVASLGMSPVAVRPLLAFAGHRVDAELGRV
                     RLLGEREIGPALLSERTRLSGESVRALTEHLARVFPEYQAPPPAAPSPPAVTSQDAATR
                     PPDAGSDGLFDLDGLREAALDEARRAPIEQWMTFLDPDQLALVRRNWAGPARISGPAGT
                     GKTVIALHRAAYLAQRTNGRVLYVTFANNLPRVQATFLKTMAPAVADRIDFRSLHSWAQ
                     EYLRDRGIPVHLHKEKAETAFSFAWKHLGRNSCLTEIDPQHPYWREEIDYVIKGRGITS
                     FEEYAALPRRRRRAGLRRPHRQAVWSLYEAYEAERTERAVHDFNDVLSLALAEAAGRTG
                     HSGYTAVVVDEVQDLTLVGVRLLHALVGDTPNGLLLVGDGQQAVYPGGFRLSDAGIDIR
                     GDRGQVLRANYRNSKEIVDTALSVVAEDAFEDLDGLRTPGRRDIDLTYHDGEVQRAVYP
                     TPAAHDEALLTALRGLTPQELAGSAVLCPAKRAIEHYHRLLTRAGLPVCSLDRYDGHPV
                     EAVKLGSYRRAKGLEFKRVYLPQHDTPPPTGCPDGRTPGEAAHERAELARSQLYVAMTR
                     ARDVLWLGSVRG"
     misc_feature    complement(9664..9666)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(9883..>10041)
                     /db_xref="GeneID:96284137"
                     /locus_tag="STRTU_RS16270"
                     /old_locus_tag="STRTU_003253"
                     /pseudo=""
     CDS             complement(9883..>10041)
                     /codon_start=1
                     /db_xref="GeneID:96284137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003949725.1"
                     /locus_tag="STRTU_RS16270"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_003253"
                     /product="DUF397 domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="SGRPGGRCIEWAPEHASATGKFLVRDSKDPKGPRLTLTRQGFAGL
                     VEFAKSE"
     gene            complement(10001..12250)
                     /db_xref="GeneID:96284138"
                     /locus_tag="STRTU_RS16275"
                     /old_locus_tag="STRTU_003254"
     CDS             complement(10001..12250)
                     /EC_number="4.2.3.-"
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96284138"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089895.1"
                     /locus_tag="STRTU_RS16275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_003254"
                     /product="terpene synthase family protein"
                     /protein_id="WP_159744172.1"
                     /sec_met_domain="T1TS (E-value: 1.9e-82, bitscore: 276.6,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQPFELPHFYTPHPARLNPHLEAARTHSRTWAREMGMLEGSGIW
                     EQRDLDAHDYALLCSYTHPDCDADALSLVTDWYVWVFFFDDHFLETFKRTLDRKGGKEY
                     LDRLPAFMPMDLTTPVPEPVNPVEAGLADLWARTVPRMSMDWRRRFAESTEHLLNESLW
                     ELSNIHIHRVPNPVEYIEMRRKVGGAPWSAGLVEYATGAEVPAAVAASRPLRVLRDTFS
                     DGVHLRNDLFSYQRETEEEGELSNGVLVLEHFLNCTTQEAADAVNDLITSRLQQFENTV
                     VAELPALFLEKRLDPTSCAEVLAYAKGLQDWQSGGHEWHMRSSRYMNGGGAAAGSAQPW
                     SPFSLGGLGTSAADLKTALATAGALRLRSGTHLPYRQVGPSQLPDFCMPFTTSLSPHLD
                     GARQRLVDWAHRMGLLQPQPGVPLSGIWDEPALIRHDLALCAAGIHPDATPEQLDLSSA
                     WLAWGTYADDYYPAVFGRTRDRASATVCTERLSAFMPLDSATPPPEPVNALERGLADLW
                     PRTTAAMAPEARRAFRDAVDTMTASWLWEIDNQIQHRIPDPVDYIEMRRATFGADLTMS
                     LRRIGHDRTVPPEIYRTGTLRSLQNAAADYAGLLNDVFSYQKEIEYEGEVHNGILVVQT
                     FFGCDYPTALHIVHDLMTSRMREFQHVATHELPVVCDDFQLAPEAREALHDHVRELEHW
                     MAGILIWHRDCLRYRSSELRHPTGSPGRLAAPTGLGTSAAGLFRSARRSVHRVGT"
     gene            complement(12407..13327)
                     /db_xref="GeneID:96284139"
                     /locus_tag="STRTU_RS16280"
                     /old_locus_tag="STRTU_003255"
     CDS             complement(12407..13327)
                     /codon_start=1
                     /db_xref="GeneID:96284139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089894.1"
                     /locus_tag="STRTU_RS16280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_003255"
                     /product="RimK family alpha-L-glutamate ligase"
                     /protein_id="WP_246240631.1"
                     /transl_table=11
                     /translation="MRICLLTADPGHPLLAAVSDLLAPDHQVETLDPGAEGPGPDLSSL
                     ADVYLLKARTPRALALAALLEEHGAPVLNSAAATARCQDRVAMAAVARAAGLPFAGTRC
                     VAALGELAAAGAPPGPLVIKSRFSRRHDLVARADSAVRLRELAADWAEEPVVAQDFVPN
                     SGWDHKLWVVDGQLFAALRRSELAPDGRGPNLPLPTAELPASWTAAALQVGEVFGLDVY
                     GVDILDAGGAEAGGGDADGAAGAPLIVDINAFPGIRGQAGAPEALAALALRTATSGRTR
                     GRTTDRTTAQPLTPDERKLPQVSQK"
     gene            complement(13324..14358)
                     /db_xref="GeneID:96284140"
                     /locus_tag="STRTU_RS16285"
                     /old_locus_tag="STRTU_003256"
     CDS             complement(13324..14358)
                     /codon_start=1
                     /db_xref="GeneID:96284140"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089893.1"
                     /locus_tag="STRTU_RS16285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_003256"
                     /product="RimK family alpha-L-glutamate ligase"
                     /protein_id="WP_159744173.1"
                     /sec_met_domain="RimK (E-value: 2.9e-07, bitscore: 29.0,
                     seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLCFLVEEQYRHDGMPLEVIHQLRAWGHQVDVVWPGRSLIRISE
                     AIQAGSHDAWVLKTVSGGPGLTLLEAAASVGLTTVNDVRAIRGVRDKALAAVIARSKGL
                     PVPVTYAAARPEEFAEIAEAEFPLVVKPADGSSGRAVRLVATPDRLLDPVDAVESGGAA
                     GPGGAGGGLLIAQPYVPNSGTDLKVYSVAGELYATERCSPLHPAHAVHERQVPLTTEVA
                     RITAEIGDVFGLDLYGVDILLGPDGPVVVDINDFPSFRQVPDAVARVSAAVLDLARRGT
                     RGREASVREAAREAFAGEPVREAGREPEPVSEAVSVAGLPTPPFAVPSVPRANWPAASM
                     GGGR"
     gene            complement(14564..15394)
                     /db_xref="GeneID:96284141"
                     /locus_tag="STRTU_RS16290"
                     /old_locus_tag="STRTU_003257"
     CDS             complement(14564..15394)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (26-256). E-value:
                     2.3e-23. Score: 75.0. Matches aSDomain:
                     nrpspksdomains_STRTU_RS16290_Abhydrolase_1.1"
                     /codon_start=1
                     /db_xref="GeneID:96284141"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016325548.1"
                     /locus_tag="STRTU_RS16290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_003257"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_159744174.1"
                     /sec_met_domain="PF00561 (E-value: 2.9e-17, bitscore: 61.8,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3e-20, bitscore:
                     72.4, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDALEVRTFETHDGLLAYRDAGSGRPLVLLHGGFVDGGMWDDQL
                     PYFARDHRVIVPDARGHGASANATRAFRQTDDLAALLRHLDTGPAVLVGVSMGGAMAVD
                     TALEHPGLVRALVVCGAGTSEPEFHHPWVREVRAAQARAMAAGDIEGWIDAFVMYAAGP
                     HRTLDAVDPQVVGRIRDMARRTLAKHTADEPDRHVPVTDTWARTANITVPVLVVNGTLD
                     MDDCIGMGERLVRSVAHGRSATIDGTAHYPNMERPDVFNRMVEEALHGFLAGEG"
     aSDomain        complement(14627..15316)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_STRTU_RS16290_Abhydrolase_1.1"
                     /evalue="2.30E-23"
                     /label="STRTU_RS16290_Abhydrolase_1.1"
                     /locus_tag="STRTU_RS16290"
                     /protein_end="256"
                     /protein_start="26"
                     /score="75.0"
                     /tool="antismash"
                     /translation="PLVLLHGGFVDGGMWDDQLPYFARDHRVIVPDARGHGASANATRA
                     FRQTDDLAALLRHLDTGPAVLVGVSMGGAMAVDTALEHPGLVRALVVCGAGTSEPEFHH
                     PWVREVRAAQARAMAAGDIEGWIDAFVMYAAGPHRTLDAVDPQVVGRIRDMARRTLAKH
                     TADEPDRHVPVTDTWARTANITVPVLVVNGTLDMDDCIGMGERLVRSVAHGRSATIDGT
                     AHYPNMER"
     CDS_motif       complement(15077..15136)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_STRTU_RS16290_0001"
                     /evalue="1.70E-04"
                     /label="NRPS-te1"
                     /locus_tag="STRTU_RS16290"
                     /protein_end="106"
                     /protein_start="86"
                     /score="14.2"
                     /tool="antismash"
                     /translation="TGPAVLVGVSMGGAMAVDTA"
     gene            15453..15923
                     /db_xref="GeneID:96284142"
                     /locus_tag="STRTU_RS16295"
                     /old_locus_tag="STRTU_003258"
     CDS             15453..15923
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96284142"
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669584.1"
                     /locus_tag="STRTU_RS16295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_003258"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_159744175.1"
                     /transl_table=11
                     /translation="MTDTAAPLPPDDLAHRLTEVFDLVGPLYRRVQRKVEQSAPIEGLS
                     VGVRAVLDLLRENGPMTVPQMGRAQALSRQFVQRMVNDAADRQLVEITPNPAHQRSSLI
                     RLTDDGRAAITAVLTRERALLRQVDGGLTDAEVTACVRVLTRMLALFDHVEV"
     gene            16032..16526
                     /db_xref="GeneID:96284143"
                     /locus_tag="STRTU_RS16300"
                     /old_locus_tag="STRTU_003259"
     CDS             16032..16526
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96284143"
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018559331.1"
                     /locus_tag="STRTU_RS16300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_003259"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_159744176.1"
                     /transl_table=11
                     /translation="MTSKAVPFDGLDRKIVAALIDNGRASFAEIGAAIGLSSTAVKRRV
                     DRMRENNVITGFTATVRPAALGWLTEAYVEVYCDSAAPPRRLAEVVRNHPEIAAAMTVT
                     GGADALLHVRATDVEHFEEVLERIRAEPFIRKTISYMVLSHLLPDSPEAGARQSSGGAA
                     P"
     misc_feature    16714..16727
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.79"
                     /tool="antismash"
     gene            16779..17603
                     /db_xref="GeneID:96284144"
                     /gene="ddaH"
                     /locus_tag="STRTU_RS16305"
                     /old_locus_tag="STRTU_003260"
     CDS             16779..17603
                     /EC_number="3.5.3.18"
                     /GO_function="GO:0016403 - dimethylargininase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96284144"
                     /gene="ddaH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019059544.1"
                     /locus_tag="STRTU_RS16305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_003260"
                     /product="dimethylargininase"
                     /protein_id="WP_269777463.1"
                     /transl_table=11
                     /translation="MSRVSRPRRYLVCEPRHFAVQYAINPWMRAEVPVDTALAGRQWET
                     LMGTYRAHGHTVETVAPVPGLPDMVFAANSALVVGGRVFGSQFHAPQRRPESTEYETWF
                     KAAGYDVYRPESPCEGEGDLVPAGRYILAGTGFRTTPAAHREVQEFFGVPTIGLQLVDP
                     YFYHLDTALFVLEESPETGEANIAYYPEAFSSGSREVLRRLFPDAVLATREDALAFGLN
                     SVSDGRHVFVAPLATGLIAQLSAHGYVPVPVDLSEFHKAGGGIKCCTQEIRS"
     gene            17600..18835
                     /db_xref="GeneID:96284145"
                     /gene="rocD"
                     /locus_tag="STRTU_RS16310"
                     /old_locus_tag="STRTU_003261"
     CDS             17600..18835
                     /EC_number="2.6.1.13"
                     /GO_function="GO:0004587 - ornithine aminotransferase
                     activity [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (37-358). E-value: 1e-102.
                     Score: 335.6. Matches aSDomain:
                     nrpspksdomains_STRTU_RS16310_Aminotran_3.1"
                     /codon_start=1
                     /db_xref="GeneID:96284145"
                     /gene="rocD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089890.1"
                     /locus_tag="STRTU_RS16310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_003261"
                     /product="ornithine--oxo-acid transaminase"
                     /protein_id="WP_159744177.1"
                     /sec_met_domain="Aminotran_3 (E-value: 3.8e-116, bitscore:
                     386.8, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPTRTVPAQASRSSAELIQAESPVLAHNYHPLPVVVARAEGVW
                     VEDVEGRRYLDMLAGYSALNFGHRHPALIEAAHRQLDQLTLTSRAFHNDRLAGFAESLA
                     ELTGLDMVLPMNTGAEAVESGIKVARKWAYDVKGVPADRATIVVAGGNFHGRTTTIVGF
                     SDDDTARVGFGPFAPGFRTVPYNDLAAIEAALDETTAAVLIEPIQGEAGVLIPDDGYLT
                     GVRELTRRNGCLFIADEIQSGLGRTGTTLAVEHESVVPDMLLLGKALGGGIVPVSAVVA
                     RREVLGVLGPGQHGSTFGGNPLAAAVGSAVIELLATGEFQRRAAELGTQLRSGLTALTG
                     KGVTGFRARGLWAGVDIDPTLGTGREISERLLKEGVLVKDTHGSTIRLAPPLTITAEEL
                     ESALGSLERALG"
     aSDomain        17711..18673
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_STRTU_RS16310_Aminotran_3.1"
                     /evalue="1.00E-102"
                     /label="STRTU_RS16310_Aminotran_3.1"
                     /locus_tag="STRTU_RS16310"
                     /protein_end="358"
                     /protein_start="37"
                     /score="335.6"
                     /tool="antismash"
                     /translation="VARAEGVWVEDVEGRRYLDMLAGYSALNFGHRHPALIEAAHRQLD
                     QLTLTSRAFHNDRLAGFAESLAELTGLDMVLPMNTGAEAVESGIKVARKWAYDVKGVPA
                     DRATIVVAGGNFHGRTTTIVGFSDDDTARVGFGPFAPGFRTVPYNDLAAIEAALDETTA
                     AVLIEPIQGEAGVLIPDDGYLTGVRELTRRNGCLFIADEIQSGLGRTGTTLAVEHESVV
                     PDMLLLGKALGGGIVPVSAVVARREVLGVLGPGQHGSTFGGNPLAAAVGSAVIELLATG
                     EFQRRAAELGTQLRSGLTALTGKGVTGFRARGLWAGVDID"
     gene            complement(19009..19404)
                     /db_xref="GeneID:96284146"
                     /locus_tag="STRTU_RS16315"
                     /old_locus_tag="STRTU_003262"
     CDS             complement(19009..19404)
                     /codon_start=1
                     /db_xref="GeneID:96284146"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STRTU_RS16315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STRTU_003262"
                     /product="hypothetical protein"
                     /protein_id="WP_159744178.1"
                     /transl_table=11
                     /translation="MTRPKLLRALTVAGTIALSAVATTPAAHAAASACTHDWSGPQICV
                     ETSGQNGLPNPGTVTATWTNPPKSRQSATVYITTPGVSYSFKAKRSGSQIVGRTVPGLQ
                     GTGDLCVRFKGSSHKACVELIDRNGSF"
     gene            19464..19784
                     /db_xref="GeneID:96284147"
                     /locus_tag="STRTU_RS16320"
                     /old_locus_tag="STRTU_003263"
     CDS             19464..19784
                     /codon_start=1
                     /db_xref="GeneID:96284147"
                     /inference="COORDINATES: protein motif:HMM:NF018748.4"
                     /locus_tag="STRTU_RS16320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_003263"
                     /product="DUF1348 family protein"
                     /protein_id="WP_218039306.1"
                     /transl_table=11
                     /translation="MGRGGHRVHVVDLSRISNSCAIGFRCAASATAPPINSANCRAVAS
                     GSATGTAQRPVRGAIGWSSSGNRIAVRFQYESPDTAGQWWRGVGETAAWSSSATTATGP
                     AR"
     misc_feature    19512..19527
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.62"
                     /tool="antismash"
     gene            19742..20290
                     /db_xref="GeneID:96284148"
                     /locus_tag="STRTU_RS16325"
                     /old_locus_tag="STRTU_003264"
     CDS             19742..20290
                     /codon_start=1
                     /db_xref="GeneID:96284148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003999362.1"
                     /locus_tag="STRTU_RS16325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_003264"
                     /product="YciI family protein"
                     /protein_id="WP_159744179.1"
                     /transl_table=11
                     /translation="MEFFCYHRDRPGSLTLRQELLEDHWSYMDRYAEELIARGPTLLGE
                     DGIPTGSVHIVDLPDPAAARAFAFGEPGYQAGAYRDVMLRRWRNVLGRTMWEFPGGRSG
                     GNHYLVLGLGAGQAADLSVPRDADELIAYGPLLSDDGDRWLGTAALVRAPDPATARAVL
                     TQERYADIEVHNWEFGGRR"
     gene            complement(20339..20974)
                     /db_xref="GeneID:96284149"
                     /locus_tag="STRTU_RS16330"
                     /old_locus_tag="STRTU_003265"
     CDS             complement(20339..20974)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:96284149"
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003986370.1"
                     /locus_tag="STRTU_RS16330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_003265"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_159744180.1"
                     /transl_table=11
                     /translation="MDLDEARTRILDAAEKLFYDRGIQSVGMDELRTAAGVSLKRLYQC
                     FPAKQDLVEAYLRRRDTRWRAALAEYVDAQADVPADGPAARPLAVFDWLYGWFSGPGFR
                     GCAFINAFGELGATSDGVSRAAGEHKGALLSYLTDIARGVPVPQPEAVAGQLALLVDGA
                     ITTAAITRDPDAARRARAAAETLVGAAGAGVGAGAGASASTRGSSPRG"
     misc_feature    complement(21037..21050)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.02"
                     /tool="antismash"
     misc_feature    complement(21040..21058)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.13"
                     /tool="antismash"
     misc_feature    21071..21084
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.02"
                     /tool="antismash"
     gene            21122..21583
                     /db_xref="GeneID:96284150"
                     /locus_tag="STRTU_RS16335"
                     /old_locus_tag="STRTU_003266"
     CDS             21122..21583
                     /codon_start=1
                     /db_xref="GeneID:96284150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010988867.1"
                     /locus_tag="STRTU_RS16335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRTU_003266"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_159744181.1"
                     /transl_table=11
                     /translation="MAPPRPPLPPFDEPSALQKVQAAEDAWNTRDPERIALAYTEDSVW
                     RNRDTFLTGRAEIVAFLRQKWARELNYALRKELWSYSGNRIAVRFQYESHDTAGQWWRS
                     YGNELWEFDEDGLMRRREAGIHDVAITEADRRIFGPRPEEERGRPLPFR"
     misc_feature    22001..22015
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.78"
                     /tool="antismash"
ORIGIN
        1 cgccgaagcg gcggaagagc gtgcccttgc cgacccctgc cgccgccgcg atctcgtcca
       61 tcgacacccc gcgggggctc gcactacggg caaccacgtg cacgcgcagg ccgtccgcac
      121 ccacggcacc ctcaccagcg cgaccggcac cggccgggtc ggcttcatcg acgcggagga
      181 catcgccgcc gtcgccgccc acgccctcgc cgactccccg ctccccggcc acgacctggt
      241 gctcaccggc cccgaggccc tcacctacga cgacatcgcc accaccctca ccgaactcac
      301 cggccgcccc gtccgccacc accccgtcac ccgcgaccaa ctccgcgacc atctcgccac
      361 cgccatgccc accgagttcg ccaccctgct ggccaacctg gaccacgacc tcgcccacgg
      421 cgccggctcc cacctcaccg acaccgtgga acgcgtcacc ggccacccac ccctcaactt
      481 ccgcacgcac gcggaacgtt ggtaccgcga caaccggccg cgacgggggg cgtgagcacc
      541 tgttcccgcc gcgctccggc ccgcccctca ccgccaccct cctcaccccg gctgtaacgc
      601 cgcggcgaac tgcggaagag cgaccagcag caacgccgtt cccatctcga tccagcggta
      661 tttggagcgg atgatctcgc tggtcctccg gacggaggcc agcagcggtc cggtgggatc
      721 gtgcgcgaga cgtgcgaagg cgtggctcag gacgtcgccg tcctcccccc gcccgatgtg
      781 ctcgaagtag ccgggggcgg ccacaccgcg ctctcttccc ctgcgccgcc gcggtgcgat
      841 ggcggagacg aagcagacga tggccagcag cgcggtgacg accgcgcccc accacaggac
      901 atccgccttc caggaagcgg ccgcctgacc ggacgcggag ccgcgcgtca ccgtgatgaa
      961 ggcgccgagc accgccccca tgaagcccag caacaccgcc gccttggtgt ccgcccgcgc
     1021 gatctccaca ccgttggcgg ccaggaagcg ctccatcgcc gccagcctct ccgggtgcgg
     1081 cgcctccgga gaggcgccgg ctccgcggcg gtctcgcagg gtccggtgca gccgccggtg
     1141 ggcgtacgga gacgggcgcc gccgggccat ggcggccccg ggccgggaac cccgctgagc
     1201 caccgggcgc gccggagccc actggacggc cgggcgcctc acaccgacca ctccttcgcc
     1261 gtcccgcgcg gccagccgtt cgccgccggg cgcccgggac ccttgccccc cggtgactcc
     1321 tgcggcgcgg gctgcgcggg caccgggcgc cccagccgca ggaggcggtc acgcagcagt
     1381 tcggagagtt cctgttgctc ctcatccgtc aacttgccga ggagaccggc tacttggtcc
     1441 tgccagttgg tctcctcctt gagcagactc cggtggttca ccgcccagtc cagcacctgg
     1501 ctgacctggt cggggtgccg gtgcagccag agcgcggcaa gcgccaccgg cccgttgcgc
     1561 acggcgtcgg tgcagaaggc gtactcctcg cggcgagggg tggtccagga gtacggcagg
     1621 ccgatcccgc ccggctgtcc cagccgcagc tcgccttccg attcctgtcc gcagatatcc
     1681 gtcacgcgat aggtgaggcc gaagccggcc agctcctgcg gcacggccag ctcctgcatg
     1741 atctcagggg cgccgatgct ctgcccgtcg gccgcgtagg cgtcctccag gtgccgcagc
     1801 cgccggtcga ggtccttgcg caccgcgtcc cagccgtacg aggtccgcga gcgcaccacc
     1861 tccaccgggt cgtgcaccca ccacagcacc cggacgtcca ccgactccgt tccgtacgcg
     1921 gtgggcagcc cgacgctccg ggtcccggac tgctcatgga gctggacatg gaaggcgctg
     1981 tcatagcccc ccagcagctt gggcgcggac gacgccagcg cggccacctc cggcgcgcca
     2041 atctccccgt gcggcgcccc gtagcggtta cgggacccca gcacccggta ggcaccgctg
     2101 tggtccctca gcaccagggc ccggtccagt cggccggacc agcggtgccg gaggatctcc
     2161 cgccacgggg cgtgcgcggc aagggtgtag acgggctggc tggtgtcggt ggtcatgacg
     2221 tactcccgtt caggtgcgtg ctgccgttcg ccgggtgccg gggcggctca ccgtgccgcc
     2281 aggtgttcag tgcgtcgcgc acgatggaca gtccggcgag gtcggggtca tcggcccggt
     2341 cgatggtgac gaagaggcgg aacaccccgt gtcggacgtc cgcggcgagc gcggtgagca
     2401 gggtctccac ggccgtccgc ggcaggtcac cccaggtggc catccggcac caccagagca
     2461 ccgcgttgca ggtcgccgcg aacagctcct cgtcgttgag tgtccggtgg acgaggtcaa
     2521 tgatctgcgg cgcgtattcg ccgtcgtcga ccagctgttc ctgacaccac gaggtgttct
     2581 ggagcagccg gggaaacgtc cggagcgcga catcgcccaa cgtgccctcg cggtccgccc
     2641 attcggccag atgccggaag accgtggcct ggctgccgga ggcgaacaga tcacgcaggg
     2701 cgtcgcggac cgcccggtcc acggtgcgct catgctcgtc actcaggccg cggggcacat
     2761 tccgcaacag ccgcatggcc agctcggggc gggcggcgcc gaagtccgcg ccgcaggtgt
     2821 aggcgacggt ggagcgcacc tgccagctct gctgcgcgct ccacaggctg aggcggtatt
     2881 tgacctcgcg ggccaggacg ggatcctcgg ccgccatgcc cagcgcgtac gcggcgatgg
     2941 tgcggctggt cctgcggttc gactcggcga gggtgcggat gtgctggagg gcccggcggc
     3001 ccccgcccca gccggccgcc cggcccatca cccggcccac cggttcggtc agctcctgct
     3061 cgttcctgag gtccgccatc cactcggtca gcagaccgga gaggtgtccg tactcccgcc
     3121 agacgtgccg cagcacggcc tccgcctgcc ggtggcgggt gaagcgcacg gcctccacgg
     3181 cataggtgta gccggggttc gagtggatct cgctggcgga acgctctgcc cgtacgctcc
     3241 gcaggagttc gtccagcgac cgccggaaga cgaactgcgg attgggccgc ggcgtccgct
     3301 cccgttcgcg ccgcccgtcc tcgccggagt cgtcggcgcc ctccggcagt acggagctga
     3361 gccggccgtc cgccagcgcg aggagccgct ccgcctcctc ccgaacgatc cggtggtcca
     3421 ggccctcgaa cacgcaggtc gcgaggagga aggcgagtcc gtcggcgtcg tcccgcagct
     3481 gcgcgagcag atccggcacc tcgccctccg cgaggaagct cagccgtttc tggaggtcgg
     3541 cgaggtccgg tccgccgtcc tccgccgcgg ccaccgcggc gaccagctcg gccacctggg
     3601 ccggcaccag ctccggggcg agcaactcgt ccagcagacc gggctccagg gctgccagcc
     3661 gccgggcgcg ctccgacggg tccggcaccg cgtgcttgaa gcgggcgtcg aacaccgccc
     3721 gcgcgggcgg tggcgcacac cggacgggag tgacatgcag gtcgcgcgac agccgccgga
     3781 ccagctccgg ggcgtccggc agcaccacca ccatgcgggc atcggcggtg ctcagcaggc
     3841 tctggagatg gcggaccatc cccggcttca gggggtagtc gggcagcagc ccgtccacca
     3901 gatagccgcg ggtgtcgcgg tgaccggggc gccaggaggc cagattcata tcgccgtcaa
     3961 cggcccgcag gctcatgctg ccgccgctgt gccggctcag cagattgagc gccgcggtgc
     4021 ggcggccggt gccgggctcg ccggtgagga acagcagccg gctgtcgagt tcggccagcg
     4081 cctcggggaa ccagtcgggc tccgcgaacc ccgcctgcgc gtccaggatc tcgatcgcgg
     4141 agatgggccc ctcgtgcgcc tcgacccgcc gaccgccggt tccggttccg gtggcagcgc
     4201 cgccgttctc cactcgctgc ccgccgtgca cggaaccgtt gttgatgttg gcgccggggg
     4261 cgaagatcac cgagtgcggc tgaccgccga acggccgacc ggcaaacggc ggaccggcga
     4321 actccccgcc gtggagcgcg aactccgccg ccgccgcatc gaactccgct gccgtttcgt
     4381 cgaagtcccc gtcgtccggg tccgcgaagc cgatgtcgcc ctcgggcggc tccccgcccg
     4441 ctgccggtgc ttccggctcc tcgcgcgtcg ttccgtccgt cccccgcggg agagccggac
     4501 gcgcgtcctc ggcgctcatc ggcggtcctc gcgcttgtcg ccgtgaaccg tgtcgccctg
     4561 attcccgtgg accgtgccgg ccttgttacc gccgacgtag tcaccgccga agcggtcacc
     4621 gcgcacgtag tcgccgccca cggagccgat ggagtcgccg ccggtgtagt cgccaccgac
     4681 gccgccggac tcgacattcc ggacgctctg gccgccgtac acggtcccgt tgttgacatt
     4741 ccccttgtcg gcccggatcc gcacctgcgg ggcggcggcc cggcgcccgg cgccccggga
     4801 ctccgcaccg cgctcgccgc gccccgactc gtgatcctcg atcacccggt ccccgaggat
     4861 gcggcggtcg tagagattgc ccgacggggc ggggacatac agccaggccg cctgctcgaa
     4921 ctgcttgccc tcgacggtcg ccggcacctg gaaaaagtgg tcggggtgcc gcccggtgta
     4981 gccgctcacc accgcgtcct gatagcagcg gtcggagagg atggcggcaa catgggtgat
     5041 attggcgctg gaggccgcca gcatcgcctt gaccggacgg gagtcgagca gccggtgggt
     5101 gtcgttgcgc ggggtgccgt tgccgtcgta ctcctcgccc gcgtcgggca gcggcccgat
     5161 gtgcagactc accctgagcc ggatgcgcac cgccccggtg gagtgcacat ggaactcggt
     5221 caggacctcc tgcagggtgc tcagccaggg gtggatgacg aacggcatct tcgccgggtc
     5281 gaagccgaag acatacccgt cgcccgtgga accggggaac ctgcgctccg cccagacctc
     5341 cgcgatcccg gcgcgctcga acgaggtctg gaggagctgg gggatggcgc ggctgatctc
     5401 cccgtgctcg atcgccggat atccggtgaa gtccttggcg tcgaccgcca cgatcccccg
     5461 gtacggcggc agcggccggc tgcgggaata gggctgcgca ctggcttcgg gcaggtcggg
     5521 gcggcgggac ggtgacatcg gaactccttg gctttcccgg gcggtcttca cctggtccat
     5581 ggacacctga cggaccgtcc atggacctgg ggccgaaccc tcgttcagct ccacgccccg
     5641 agtctcgcga gcggtggctt cccggtgtgc acccgcggtg cactgacggc gtgacgcgca
     5701 ccacaccgcg ccggaatcac tccccgggag cggcggccac ccggcgcagg gcggtcagat
     5761 ccccgatgac gatgcgcttc cgtccggcct gcacctcgca ggactccagc ccggcgagcg
     5821 tcgccgtgat cgtgttacgg gacaccccca ggtactgggc cagctcatgg cgggtgaggg
     5881 ccagttccag cggttcgccg ggacggctgg ccgggtgccc ggagatatcg gccaggccca
     5941 cgagggtggc cgccagccgg gtcagggtgc tgccaccgcc gccgcgggct tcgtccgact
     6001 cccgcatcct ggtgaaggcg taccgcatca gcaccggaaa caggtcgtgc gccacgacga
     6061 accgcaggaa ctccgccttg ccgatgaccc ccacggtgca cgacgagatc gtctcgacgc
     6121 tcgccgaccg cacgtcgtcg tccaacaccg ctacctcgcc gagcagttcc ccgggtccac
     6181 ggaacgccag cagcgtgagg tccccgctcc gctcgcgccg gagcaccttg gccaccccgc
     6241 tcagcacggc cagcacatgc gtcccgggct ccccctgacg gagcatcatg ctcccggcgg
     6301 ggtgccgccg ctcgaagacc tggcccagca ggtcccgcca ggccgcatcc cccacgaagt
     6361 gccgcagcgt ccggcctgcc ggcaccgccg ctccccctac ccgatcaccc atggggcgac
     6421 tctaggggct gcctgcccgc ctcttccctc tgcacgggca gaaagcacgg ctcgctgcga
     6481 cgggagacgg cgcgggcccg cggcgacggc gcggcccgcg gcgcggaaag caccacgggc
     6541 cgcggccacg agccgtcccg gccgtgcccc gccctgcccg cccccctcaa ccccgtctca
     6601 gcccgcggcc cccgggcgcc cgtgtcggcc cggccgtccc gggctcccgg cgttcaccgg
     6661 gtccagcggg ctcgctgcat gcgtgggccg cttacggttc tgcgggctgc ccgtgctccg
     6721 cgcatcaccc gggtggtcgg agtggtccaa gtcgtcggag gggtcggagg ggccggacgg
     6781 gtcccggcgg ttggaggtgt ccgcggcatc ggaacggttc ggacggtcgt tgtcggcgga
     6841 gtcccggtcg ttgacagggt cccggtcgtc ggcggagtcc cggtcgttga cggggtcccg
     6901 gtcgtccgag cggtccgggt catccgaacg gtccgggttg tccgagcggt cgtcatccga
     6961 ggggcggtcc tcgtcggcgc ggcggtcctc atcagcccga cggtcctcgt cagcgcgacc
     7021 gtcctcatca gcgcgccggt cctcatcggc cgaggggacc ggctcccggg ggccgttcgc
     7081 gctcagctgg aggctgccga acttggcgtt gcgccagccg cgggcgggca cgacgaccac
     7141 cacggagccg gtgcagtcgc ggccggtgta caggacgagg tcggtgggcg tgtcgttgtc
     7201 cacctcgccg tagccgtccc cgaccccgta gcagtggtcg tcgccggggt cgaggatctc
     7261 gtgcggacgg ttctcgggcc gggtgtggaa cgtgatgacg ccggtcacgg catgcgcgcc
     7321 ggagggagcg aacgcgacga gccccccggt gagagccagc gccccaagga aagcgatctt
     7381 gcgtcgcaca gtcggaactc ctgtcagcca tggcagcggg ccggtcctgg gactggccct
     7441 tacggaacgt cgccatgtgg ggttcccgac gccttcaccg gatattccgg tcttatgcga
     7501 tattcaccag gcagcaggac atttcggggt gacgcggtgc gtgtggatgg ccccgcccgg
     7561 ctccgcccgt acgccgcccg tacgcccctc cgacggcccc ggccccggct cagcccgccc
     7621 cgccccgcat cacccacgga cgctccccag ccacagcaca tccctggccc gggtcatggc
     7681 gacatagagc tgactgcgag ccagttccgc gcgctcatgg gcggcttcgc cgggggtgcg
     7741 cccatccggg caccccgtag gcggcggggt gtcgtgctgc ggcagataga cgcgcttgaa
     7801 ttccaggccc ttggcacggc ggtagctgcc gagcttcacg gcctcgaccg ggtgcccgtc
     7861 gtagcggtcc agggagcaga ccggcagccc ggcccgggtg aggaggcggt ggtagtgctc
     7921 gatggcgcgc ttcgcggggc agaggacggc ggaacctgcc agctcctgcg gggtcagccc
     7981 gcgcagcgcg gtcagcagcg cctcgtcgtg cgcggcaggg gtggggtata cggcgcgctg
     8041 cacctcgccg tcgtggtagg tcaggtcgat gtcccggcgg cccggggtgc gcagcccgtc
     8101 gagatcctcg aaggcgtcct cggccactac ggagagcgcg gtgtccacga tctccttgct
     8161 gttgcggtag ttggcgcgca gcacctggcc gcggtccccg cggatgtcga tgcccgcgtc
     8221 cgagagccgg aatcctcccg ggtagacggc ctgttggccg tcgccgacca ggaggagccc
     8281 gttgggggtg tcgcccacca gggcgtgcag caggcgcacc ccgacgaggg tcaggtcctg
     8341 gacctcgtcc acgacgacgg ccgtatagcc gctgtggccg gtacgcccgg ccgcctcggc
     8401 gagtgcgagg gagagcacat cgttgaagtc gtgcacggcg cgctcggtgc gctctgcctc
     8461 gtacgcctcg tacagggacc agacggcctg ccggtgcggg cggcgcagac cggcgcgtcg
     8521 gcggcggcgc gggagggcgg cgtactcctc gaaggaggtg atgccgcggc ccttgatgac
     8581 gtagtcgatc tcttcccgcc aatacgggtg ctgcggatcg atctcggtca gacagctgtt
     8641 ccggccgagg tgtttccagg cgaagctgaa ggccgtctcc gccttctcct tgtgcaggtg
     8701 gaccgggatg ccgcggtcgc gcagatactc ctgcgcccag gagtgcaggc tgcggaagtc
     8761 gatccggtcg gccaccgccg gggccatggt cttcaggaag gtggcctgta cgcggggcag
     8821 gttattggca aacgtgacgt acaggacgcg gccgttggtg cgctgggcga gataggcggc
     8881 gcggtgcagg gcgatgaccg tcttgccggt gcccgccggg ccgctgatcc tggccggacc
     8941 ggcccagttg cgccgtacga gcgcgagctg atcggggtcc aggaaggtca tccactgctc
     9001 aatgggcgcc cggcgcgcct cgtcgagagc ggcttcccgc agcccgtcga ggtcgaagag
     9061 cccgtccgac ccggcgtccg gtggccgggt ggcggcgtcc tgcgacgtga cggcgggcgg
     9121 cgacggtgcc gcgggcggcg gggcctggta ctcgggaaag acccgcgcca gatgctcggt
     9181 gagggcgcgg acggactccc cggacagccg ggtgcgctcc gacagcagcg ccggtccgat
     9241 ctcccgctcg cccagcagcc gcacccgccc cagctccgcg tcgacccgat gccccgcgaa
     9301 ggccagcagc ggccgcaccg ccaccgggga catccccagg gacgccaccg cgctctccgc
     9361 ggccttggtg accgcgagca gcttgcggcg gtgctcatcg cgggagaagc cgccggcccg
     9421 cagccggccc ccggatatct ccggtgcggc ccgccagttc ttgacgtcga tgacgaagac
     9481 cccgccggga ccgatcagca gcatgtccac attggccgca cgggtaccgg gccagcgccg
     9541 gtccacgagc agccgccagc cccgctcggt cagcatcagc aactgggcgg cgacccgctg
     9601 ctccccctca ctcgccgcct cccagcgctc ggcccgctgc cgggcggcct gccactgctc
     9661 ccgtaaaagg cgctcctgcc gacgtgcctg ctgcgcccgc cgcgccgccg aagccccggc
     9721 cgacctgccc accgcactcc ctgccgccat cgtccgcccc ctcaccgctc gcccccgtag
     9781 gaatgagcca agaaccctag gtcccggacc gcatgccacg gaagtgcgca cgggaggggc
     9841 acgggcgcat gacgcggagg gtccgcgggg aggcggccga cactattcgg acttggcgaa
     9901 ctccacgagc ccggcgaacc cctggcgggt cagtgtcagc cgcggaccct tggggtcctt
     9961 gctgtcacgg accaggaact ttccggtggc ggacgcgtgc tcaggtgccc actcgatgca
    10021 ccgaccgccg ggccgaccgg aagagccccg ccgccgacgt ccccaacccg gtcggcgcgg
    10081 ccagtcggcc cggtgaaccc gtcgggtggc gcaactcgga ggagcggtag cgcaggcagt
    10141 cgcggtgcca gatgaggatg ccggccatcc agtgttccaa ctcgcggacg tggtcgtgca
    10201 gtgcctcgcg ggcctcgggg gcgagttgga agtcgtcgca gacgacgggg agttcatggg
    10261 tcgcgacgtg ttggaactcg cgcatgcggg aggtcatcag gtcgtggacg atgtgcagcg
    10321 cggtcgggta gtcgcagccg aagaaggtct ggacgaccag gatgccgttg tggacctcgc
    10381 cctcgtattc gatctccttc tggtaggaga agacatcgtt cagcaggccc gcgtagtcgg
    10441 cggcggcgtt ctgcagtgag cgcagggtgc cggtgcggta gatctccggc gggaccgtgc
    10501 ggtcgtggcc gatgcggcgc aggctcatgg tgaggtcggc gccgaaggtc gcccggcgca
    10561 tctcgatgta gtcgaccggg tcggggatgc ggtgctggat ctggttgtcg atctcccaga
    10621 gccagctggc cgtcatcgtg tcgacggcgt cccggaaggc ccggcgcgcc tcgggggcca
    10681 tggcggccgt cgtacggggc cacaggtcgg ccagcccgcg ttcgagggcg ttgaccggct
    10741 cgggcggcgg tgtcgcggag tcgagcggca tgaaggccga cagccgctcg gtgcagaccg
    10801 tggccgaggc gcggtcgcgg gtgcggccga agaccgccgg gtagtagtcg tcggcgtagg
    10861 tgccccaggc cagccaggcg gagctgaggt ccagttgctc cggggtggcg tccgggtgga
    10921 tgccggccgc gcagagcgcc agatcgtgcc ggatcagcgc gggctcgtcc cagatgccgg
    10981 agagcggcac accgggctgc ggctggagga ggcccatccg gtgcgcccag tcgacgagcc
    11041 gctgccgggc gccgtccagg tgggggctga ggctggtggt gaacggcatg cagaagtcgg
    11101 ggagttggga cgggccgacc tgccggtacg ggaggtgggt gccgctgcgg aggcgcagcg
    11161 caccagccgt ggccagggcg gtcttcaggt ccgccgccga ggtgccgagg ccgccgaggg
    11221 agaagggcga ccagggctgc gcgctgccgg ccgcggcgcc gccgccgttc atgtagcggc
    11281 tggagcgcat atgccattcg tggccgccgg actgccagtc ctggagcccc ttggcgtacg
    11341 ccagcacctc ggcgcaggac gtcgggtcga gcctcttctc caggaagagc gcggggagtt
    11401 cggcgaccac cgtgttctcg aactgctgga gccgggaggt gatcagatcg ttgacggcgt
    11461 ccgccgcctc ctgggtggtg cagttcagga agtgctccag taccaggacg ccattgctca
    11521 gctcgccctc ctcctccgtc tcccgctggt aggagaagag atcgttccgc agatgcacgc
    11581 cgtcggagaa ggtgtcccgc agcacccgca gcggccggga ggcggcgacg gccgcgggca
    11641 cctcggcgcc ggtcgcatac tccaccagcc ccgccgacca gggcgcacca ccgaccttgc
    11701 ggcgcatctc gatgtattca acggggttgg gcacccggtg gatatggata ttggacagtt
    11761 cccacaacga ctcattgagc agatgctcgg tgctctcggc gaaccgccgc cgccagtcca
    11821 tggacatccg cggcaccgta cgcgcccaca ggtcggcgag cccggcctcg accgggttga
    11881 ccggctccgg tacgggcgtg gtcagatcca tcggcataaa ggcgggcagc cggtccaggt
    11941 actccttgcc gcccttccgg tccagcgtcc gcttgaacgt ctccaggaag tggtcatcga
    12001 agaagaagac ccagacgtac cagtcggtca ccagcgagag cgcgtcggcg tcgcagtccg
    12061 ggtgggtgta ggagcacaac agggcgtaat catgggcgtc gagatcccgc tgctcccaga
    12121 tacccgagcc ctccagcatg cccatctccc gggcccacgt cctggagtgc gtacgggcgg
    12181 cctccaggtg ggggttcaac cgcgccggat ggggcgtgta gaagtgcggc aattcaaatg
    12241 gctgtgtcac ggttgctggc ctctccccat acgtacggaa ggaaggcgcg ctgcaccacg
    12301 cctcccttga cggggctgcg ctaccccggg gctcagcgcc ttaggcctta tggaggagga
    12361 gcttccgcct ccgctcccct tgggtccgga gtgggccgaa ccgggatcat ttctggctga
    12421 cttgtgggag ttttctttcg tcgggggtga ggggctgggc ggtggtccgg tcggtggtcc
    12481 ggcctctggt ccggccgctc gtcgccgtcc gcagggcgag agccgccagc gcctccgggg
    12541 caccggcctg gccgcggatc ccggggaagg cgttgatgtc cacgatgagg ggcgcaccgg
    12601 ccgcaccatc ggcatcgccg cccccggctt cggcaccacc ggcgtcgaga atgtccaccc
    12661 cgtagacgtc caggccgaag acctcgccga cctggagcgc ggcggcggtc cagctcgcgg
    12721 gcagctcggc ggtcggcagc ggcaggttcg ggccgcggcc gtccggggcc agctccgagc
    12781 ggcgcagcgc ggcgaagagc tgtccgtcga ccacccacag cttgtggtcc cagccgctgt
    12841 tcgggacgaa gtcctgcgcc accaccggct cttcggccca gtcggcggcc agttcccgca
    12901 gccgtacggc gctgtcggcg cgggccacca ggtcgtggcg gcggctgaac cggctcttga
    12961 tcaccagcgg gccgggcggt gcgccggccg cggccagctc cccgagggcg gccacacagc
    13021 gggtaccggc aaacggcagc cccgccgcgc gggccaccgc cgccatcgcc acccggtcct
    13081 ggcaacgggc ggtcgccgcc gccgagttga gcaccggggc gccgtgctcc tccagcagcg
    13141 cggcgagcgc cagcgcccgc ggcgtccggg ccttgaggag atagacatcg gcgagcgagg
    13201 agagatcggg ccccggcccc tcggcacccg ggtccagggt ttcgacctgg tgatccggtg
    13261 ccagcaggtc actgaccgcc gccagcagcg gatgcccggg atcggcggtg agcagacaaa
    13321 tcctcaccgg ccaccaccca tcgacgccgc gggccagttg gcacggggaa cggacggcac
    13381 ggcgaacggg ggcgtcggca gcccggccac ggacaccgct tccgacaccg gctccggctc
    13441 gcgcccggcc tcccgtacag gctccccggc aaacgcctcc cgagccgcct cccgtacaga
    13501 cgcctcccgc cccctcgtcc ccctacgggc gaggtccagg accgcggccg acacccgggc
    13561 gaccgcgtcc ggcacctgac ggaagctggg gaagtcattg atgtcgacga ccaccgggcc
    13621 gtccggcccg agcaggatgt cgaccccgta cagatcgagg ccgaagacgt cgcctatctc
    13681 ggcggtgatc cgggcgactt cggtggtcag cggcacctgc cgttcgtgta cggcgtgtgc
    13741 cgggtgcagc ggcgagcacc gctcggtcgc gtacagctca ccggcgacgc tgtacacctt
    13801 cagatccgta ccggagttgg gaacataggg ctgcgcgatg agcagcccac cgcccgcccc
    13861 gcccggaccc gccgcgccgc ccgactccac cgcatccacc ggatccagca gccggtccgg
    13921 cgtcgccacc agccggacgg cacgcccgga gctgccgtcc gccggcttga ccacgagggg
    13981 gaactccgcc tcggctatct ccgcgaactc ctcgggacgg gccgccgcat acgtcacggg
    14041 gacgggcagc cccttgctcc gggcgatcac cgcggccagc gccttgtccc gtacgccacg
    14101 gatggcccgg acatcgttca ccgtcgtcag cccgacggaa gcggccgcct ccaggagcgt
    14161 cagacccggc ccgccggaga ccgtcttgag gacccaggcg tcgtggctgc ccgcctgtat
    14221 cgcctcggat atccggatca gcgaacggcc gggccacacc acatccacct ggtggcccca
    14281 ggcgcggagt tggtggatca cctccagcgg catgccgtca tggcggtact gctcctccac
    14341 caggaagcag agtctcatcg gtgcaccctc gtcatcgccg cacgtccacc gtccgtccgg
    14401 cagatccatg acaccccagg atcccatgcg gccccacgga gccggggtgg acccacgcac
    14461 gcggcgaccg gcgaccgacc accggtcacc ggccgcacct gcttctcctg ccacggcccc
    14521 gtgacctggg cctacgccgt gaccggttgc gcggccccgc gcctcagccc tcgcccgcga
    14581 ggaagccgtg caacgcctcc tccaccatcc ggttgaacac gtccggccgc tccatgttgg
    14641 ggtagtgcgc ggtgccgtcg atggtggcgc tgcggccgtg cgcgacggac cgcacgaggc
    14701 gttcgcccat accgatgcag tcgtccatat cgagggtgcc gttgacgacc agcaccggga
    14761 ccgtgatgtt cgccgttcgc gcccaggtat cggtaaccgg cacgtgccgg tccggttcgt
    14821 cagcggtgtg cttggccaac gtccgccgcg ccatgtcccg tatgcgtccc acgacctgcg
    14881 gatcgaccgc gtcgagcgtg cggtgcggtc cggccgcgta catcacgaac gcgtcgatcc
    14941 agccctcgat gtcaccggcg gccatcgcac gggcctgggc ggcccggacc tcccggaccc
    15001 aggggtgatg gaactccggc tcgctggtcc cggcgccgca gaccaccagc gcgcgcacca
    15061 gaccgggatg ctccagcgcg gtgtccaccg ccatggcccc gcccatcgac acccccacca
    15121 ggaccgcggg cccggtgtcg aggtggcgca gcagcgcggc gaggtcgtcg gtctggcgga
    15181 aggcccgggt cgcgttggcc gacgcgccgt ggccccgggc gtccggcacg atcacccggt
    15241 ggtcccgcgc gaagtacggg agttggtcgt cccacattcc gccgtccacg aagccaccgt
    15301 gcagcagcac cagcggccgg ccgctgccgg cgtcgcggta ggcgagaagt ccgtcgtgcg
    15361 tctcgaaagt gcgtacctca agagcatcag tcatgacaac caaggtgcca tccctgatgg
    15421 agttttggca accaaggtgt catcctgatg ccgtgaccga caccgccgcg ccgctgccgc
    15481 ccgatgacct cgcccaccgg ctcaccgagg tgttcgacct cgtgggcccg ctgtaccggc
    15541 gcgtccagcg caaggtcgaa cagagcgccc cgatcgaggg cttgtccgtc ggcgtgcggg
    15601 ccgtcctgga tctgctccgc gagaacggcc cgatgaccgt tccgcagatg ggccgcgccc
    15661 aggccctgag ccggcagttc gtccagcgca tggtcaacga cgccgcggac cggcagctgg
    15721 tcgagatcac cccgaacccg gcccaccagc gctcctcgct gatccggctg accgacgacg
    15781 gccgggccgc catcaccgcc gtgctcacgc gcgaacgtgc actgctgcgc caggtcgacg
    15841 gcgggctgac cgacgccgag gtgacggcgt gcgtgcgggt gctcacgagg atgctggcgc
    15901 tcttcgacca cgtcgaggtc tgacctcccc cgccccgtat cgctaccgtg aggccacccg
    15961 caccgacgcg ggaccgggac gggaccaggc atccgaccgg ggacgggacc ggcatggaat
    16021 cgggaggccc agtgaccagc aaggccgtgc ccttcgacgg gctcgaccgc aagatcgttg
    16081 cggcgctgat cgacaacggc cgggcgagct tcgcggagat cggggcggcg atcgggctgt
    16141 cgtcgaccgc ggtgaagcgg cgggtggacc ggatgcggga gaacaacgtc atcacggggt
    16201 tcaccgcgac cgtgcgaccg gccgcgctgg ggtggctgac cgaggcgtat gtcgaggtgt
    16261 actgcgacag cgcggcgccg ccccgccggt tggctgaagt ggtgcgcaac cacccggaga
    16321 tcgcggcggc gatgaccgtc accgggggcg ccgacgcgct gctgcacgta cgggcgaccg
    16381 atgtggagca cttcgaggag gtgctggaac ggatccgggc cgagccgttc atccgcaaga
    16441 cgatcagcta catggtgctg tcccatctgc tgccggacag cccggaggcg ggcgcccggc
    16501 agtcctccgg aggcgccgca ccctgaaggc ccggggcgcc gccccctgag ggccccggag
    16561 gaaccgcccg ctaaaacgga agggtcctca gcccgcacca tcgcgccaga atgctgcgtg
    16621 aacggccacc tatacgcagc attactgcgc cgctgagcag catttgtttc ttgtggcccg
    16681 aatccctcgc tccttaccgt ggaagcactc cgggtgaccc tctgtgacct ccggtcaccc
    16741 gcaagccccg ttgcaagcga agggatcgtc ccgtgccgat gagtcgtgtg tcgcgccccc
    16801 ggcgctatct ggtctgcgag cccagacact tcgctgtgca gtacgcgatc aatccatgga
    16861 tgcgtgcgga ggtgcccgtc gacaccgcgc tcgccgggcg ccagtgggag accctgatgg
    16921 gcacctaccg cgcgcacggg cacaccgtgg agacggtggc cccggtgccc ggcctgccgg
    16981 acatggtgtt cgcggcgaac tccgcgctcg tcgtcggcgg ccgggtcttc ggctcgcagt
    17041 tccacgcgcc gcagcggcgc ccggagtcca cggagtacga gacctggttc aaggcggccg
    17101 gctacgacgt ctaccgaccg gagtcgccgt gcgagggcga aggtgatctc gtaccggccg
    17161 gccgctacat cctggcgggt accggctttc gcaccacccc ggcggcgcac cgcgaggtgc
    17221 aggagttctt cggtgtgccg acgatcggcc tgcagctggt ggacccgtac ttctaccacc
    17281 tggacaccgc gctgttcgtc ctggaggagt caccggagac cggcgaggcg aacatcgcct
    17341 actaccccga ggcgttctcg tccggcagcc gtgaggtgct gcggcggctg ttccccgacg
    17401 cggtgctcgc cacccgggag gacgccctgg ccttcggcct caactccgtc tccgacggcc
    17461 gccatgtctt cgtcgcccca ctggcgaccg gcctgatcgc tcagctcagc gcgcacggct
    17521 atgtccccgt ccccgtcgac ctgtcggagt tccacaaggc cggcggcggc atcaagtgct
    17581 gcacccagga gatccgctca tgaccgctcc cacccgtact gtcccggccc aggcttcccg
    17641 ttcgtccgcg gagctgatcc aggccgagag cccggtcctc gcgcacaact accacccgct
    17701 gcccgtagtg gtcgcgcgtg ccgaaggggt ctgggtcgag gacgtcgagg gccgccgcta
    17761 cctcgacatg ctggccggct attcggcgct caacttcggc caccgccacc cggccctgat
    17821 cgaggccgcg caccgccagc tcgaccagct caccctcacc tcccgcgcct tccacaacga
    17881 ccgtctcgcc ggtttcgccg aaagtctcgc cgaactgacc ggtctggaca tggtgctgcc
    17941 gatgaacacc ggcgccgagg cggtggagag cggcatcaag gtcgcccgca agtgggccta
    18001 cgacgtcaag ggcgtcccgg cggaccgggc gacgatcgtg gtggcgggcg gcaacttcca
    18061 cggccggacg accaccatcg tcggcttctc cgacgacgac accgcccggg tcggcttcgg
    18121 cccgttcgcc cccggcttcc gcaccgtccc gtacaacgat ctcgccgcga tcgaagccgc
    18181 cctggacgag acgacggccg ccgtgctgat cgagcccatc cagggcgagg cgggcgtcct
    18241 catccccgac gacggctacc tcaccggcgt acgcgaactg acccggcgca acggctgtct
    18301 gttcatcgcc gacgagatcc agtccgggct gggccgcacc ggcaccaccc tggcggtcga
    18361 gcacgaatcc gtggtgccgg acatgctgct gctcggcaag gcgctcggcg gcggcatcgt
    18421 cccggtctcc gcggtcgtcg cccgccgcga ggtgctcggc gtgctcggcc ccggccagca
    18481 cggctcgacc ttcggcggca acccgctggc ggccgcggtc ggttcggccg tgatcgagct
    18541 gctggccacc ggcgagttcc agcgccgcgc cgccgaactc ggcacacagc tgcgcagcgg
    18601 cctgaccgcc ctgaccggca agggcgtcac cggcttccgc gcccgcggcc tgtgggcggg
    18661 cgtcgacatc gaccccaccc tgggcacggg ccgggagatc agcgaacggc tgctgaagga
    18721 aggcgtcctg gtcaaggaca cccacggctc gacgatccgg ctggccccgc cgctgaccat
    18781 caccgcggag gaactggagt cggcgctggg gagcttggag cgggcgctgg gctgacccgg
    18841 cacccacccc cgtacgcgcc aaacccgccg tacgcgaacc ccgccgtacg ccgacgcggc
    18901 cgcagcccct ggagagctgc ggccgcgtcc ccgtcccatg gtgcagccgc gccgcgccta
    18961 ccgcgtggcg ccgtcgtacg gccgcctcgg gcgtccgtaa cggaccggct agaaggagcc
    19021 gttgcggtcg atcagctcca cacaggcctt gtgcgagctg cccttgaaac ggacacagag
    19081 atctccggtg ccctgaagtc cgggcaccgt gcgaccgacg atctggctgc cggaccgctt
    19141 cgccttgaac gagtaggaga cgccgggcgt ggtgatgtag acggtcgcgg actgccggct
    19201 cttgggcggg ttggtccagg tcgcggtgac ggtgccgggg ttgggcagac cgttttggcc
    19261 actggtctcg acgcagatct gcggccccga ccagtcgtgg gtgcaggcgg acgccgcggc
    19321 gtgcgcggcg ggggtggtgg cgacggcgct cagcgcgatc gttccggcga cggtcagcgc
    19381 gcggagcagc ttcggacggg tcatgtgtgg ggggattcct ctcctcggaa tacgggcgga
    19441 agacacgaag aatcccgcca tgaatggggc gtggcgggca ccgcgtgcac gtagttgatc
    19501 ttagtcggat ttcgaactca tgtgccatcg gctttcgttg cgcggcatcg gcgaccgccc
    19561 cgccaatcaa cagcgccaac tgtcgggccg tcgcctccgg ttcggccacc ggaaccgccc
    19621 agcggccggt ccgcggggcc atcggctggt cgtccagcgg caaccgcatc gcggtgcgct
    19681 tccagtacga gtcccctgac acggccggcc aatggtggcg cggcgtggga gagactgcgg
    19741 catggagttc ttctgctacc accgcgaccg gcccggctcg ctgacgcttc gccaggagct
    19801 gctggaggac cactggtcct atatggaccg ctacgccgag gagctgatcg cccgcggccc
    19861 cacgctcctc ggcgaggacg ggatacccac cggcagcgtc cacatcgtcg acctgcccga
    19921 tccggccgcc gcccgcgcct tcgccttcgg cgagcccggc taccaggccg gcgcctaccg
    19981 ggacgtgatg ctgcgccgct ggcggaacgt cctggggcgc accatgtggg agttccccgg
    20041 cggccggagc ggcggcaacc actacctggt gctcggcctc ggcgcggggc aggccgccga
    20101 cctctccgta ccgcgcgacg cggacgagct gatcgcgtac gggccgctgc tgtccgacga
    20161 cggcgaccgc tggctgggta cggcggcgct ggtccgggcg ccggacccgg ccaccgcccg
    20221 cgccgtgctg acccaggagc ggtacgccga tatcgaggtc cacaactggg agttcggcgg
    20281 gcggcggtga ggaccgggtg cgaggaccgg gtccggggac accgagcgcg ggccggactc
    20341 agccgcgcgg tgacgacccg cgcgtggacg cggacgcccc ggccccggcc ccgaccccgg
    20401 ctccggccgc cccgacgaga gtctccgcgg cggcccgtgc ccgccgggcg gcatccgggt
    20461 cccgcgtaat cgccgccgtg gtgatcgcac cgtcgacaag caacgccaac tgccccgcca
    20521 ccgcctcagg ttgcggcacc ggcacgcccc gtgcgatgtc ggtcagatag gagagcagcg
    20581 cgcccttgtg ctccccggcg gcccggctga ccccgtccga ggtcgcgccc agctcgccga
    20641 acgcgttgat gaaggcgcac ccgcggaatc cgggccccga aaaccagcca tacagccagt
    20701 cgaagaccgc gagcggccgg gccgcgggac cgtcggcggg cacgtccgcc tgcgcgtcga
    20761 cgtactcggc gagcgcggcg cgccagcggg tgtcgcggcg gcgcagatac gcctcgacga
    20821 ggtcctgctt ggccggaaag cactggtaga ggcgcttgag cgacaccccg gcggcggtgc
    20881 ggagttcatc catcccgacg gactggatcc cgcggtcgta gaacagcttc tccgccgcgt
    20941 cgagtatccg cgtacgggct tcatcgaggt ccatggcact tccggggctc gcgggtttgc
    21001 ggacttgtgg gctagcgggc tagcgggctt tccaggagaa cggtcgttct ctacactagc
    21061 cgaccagagg agaacgaccg ttctcccgcc cgttctcccc tcatgagcaa gggaatccac
    21121 catggcgcca ccacggccac ccctcccccc gttcgacgag ccgagcgccc tgcagaaggt
    21181 gcaggcggcc gaggacgcct ggaacacccg cgatccggag cggatcgccc tcgcctacac
    21241 cgaggactcg gtctggcgga accgcgacac cttcctcacc ggccgcgccg agatcgtcgc
    21301 cttcctgcgc cagaagtggg cccgggagct gaactacgcc ctccgcaagg aactctggtc
    21361 gtacagcggc aaccgcatcg cggtgcgctt ccagtacgag tcccatgaca cggccggcca
    21421 gtggtggcgc agctacggca acgagctgtg ggagttcgac gaggacgggc tgatgcggcg
    21481 ccgggaggcc ggtatccacg atgtcgcgat cacggaggcg gaccggcgga tcttcggccc
    21541 gcgcccggag gaggaacggg gccgccccct cccgttccgg tgatcagcgg acgccggcac
    21601 ctcccctccc ctaagaaggc ggatgtttcg ctgcgcctcg gcaggggaac taagaatccg
    21661 accgaaccaa tgggctgccc atccctcctc ggggatgcgc ggcccatcgc tttttgtgcg
    21721 atgcggggtc ggtagttgtg gcgccccgga gcgggatctc tggacggccc ccacagaagg
    21781 ggtccacatg agtacccttg ttcaatcgcc gttgcaggcc ctgctgcaga caacttcttc
    21841 cgccggccag gtaatgccgg ccgtcgaggc gggggcggtc agccggaccg cggcgccaca
    21901 caccttcctg gccgtcacga cgatcccggt cggcaccaac ccggtcgggc tggcgttcat
    21961 ccccaacggc gacctctacg tcgccaactc cgggtcgagc aatgtgcaga ccatcgacac
    22021 cgccacggac accgtcatcg gcgccgcgat cccgaccggc accacgccgg cctggctgac
    22081 cgtcgctccc aacggcaacg cctacgtccc caacaacatc tccaacaacg tgacggtgat
    22141 cgacaccgcc accagcaccg tcctcaccac gatcgcgctc agcggcgggc ccgccgcggc
    22201 ggcggtcatc cccagcggca acgtctacgt cagccgcttc gcggcgaaca
//
