LOCUS       NZ_CP114899            21612 bp    DNA     circular CON 18-FEB-2024
DEFINITION  Bacillus subtilis strain 1 chromosome, complete genome.
ACCESSION   NZ_CP114899
VERSION     NZ_CP114899.1
KEYWORDS    RefSeq.
SOURCE      Bacillus subtilis
  ORGANISM  Bacillus subtilis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 4214774)
  AUTHORS   Li,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-DEC-2022) College of Veterinary Medicine, Huazhong
            Agricultural University, Shizi street, Wuhan, Hubei 430000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v1.5 v. Hifiasm v0.12-r304
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 120.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/18/2024 04:35:17
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,515
            CDSs (total)                      :: 4,397
            Genes (coding)                    :: 4,195
            CDSs (with protein)               :: 4,195
            Genes (RNA)                       :: 118
            rRNAs                             :: 9, 9, 9 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 9, 9 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 202
            CDSs (without protein)            :: 202
            Pseudo Genes (ambiguous residues) :: 0 of 202
            Pseudo Genes (frameshifted)       :: 128 of 202
            Pseudo Genes (incomplete)         :: 67 of 202
            Pseudo Genes (internal stop)      :: 46 of 202
            Pseudo Genes (multiple problems)  :: 34 of 202
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:13:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3669140
            Orig. end                         :: 3690752
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP114899.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21612
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /region_number="10"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     cand_cluster    1..21612
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21612
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11612](-)"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11612)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     gene            complement(420..539)
                     /locus_tag="O6U12_RS19420"
                     /old_locus_tag="O6U12_19420"
     CDS             complement(420..539)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003326489.1"
                     /locus_tag="O6U12_RS19420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O6U12_19420"
                     /product="PhrC/PhrF family phosphatase-inhibitory
                     pheromone"
                     /protein_id="WP_014665774.1"
                     /transl_table=11
                     /translation="MKWKYKLLLACLAVSAVFITVEVSNSSTEHFDVAQRAMI"
     gene            complement(523..1668)
                     /locus_tag="O6U12_RS19425"
                     /old_locus_tag="O6U12_19425"
     CDS             complement(523..1668)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391626.1"
                     /locus_tag="O6U12_RS19425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O6U12_19425"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_017696253.1"
                     /transl_table=11
                     /translation="MTGVISSSSIGEKINEWYMYIRRFSIPDAEYLRREIKQELDQMEE
                     DQDLHLYYSLMEFRHNLMLEYLEPLEKMRIEEQPRLSDLLLEIDKKQARLTGLLEYYFN
                     FFRGMYELDRREYVLAIQFFKKAESKLVFVKDKIDKAEFFFKMSEVYYYMKQTYVSMDY
                     ARQAFEIYSEQTTYDIRMIQCQSLFGANFLDLKQYEKAIAHFQKAFTLAKTEQQPQLMG
                     RTLYNIALCKQNQNSFESAIEYVKKSIQVFEGSKMLPSLPQAFFLITQIYFKLGKIDNA
                     CEYHKKGKEYSAAAGDTVYLTEFEFLESLYLSGPDEERIEKCFVFLESKMMYADIEDFA
                     LDVAKYYHQQENYKKASHYFLKVEEARQHIQGGVNLYEMEV"
     gene            1671..1901
                     /locus_tag="O6U12_RS22605"
     CDS             1671..1901
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009968328.1"
                     /locus_tag="O6U12_RS22605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_017696254.1"
                     /transl_table=11
                     /translation="MQIPPFIILYMSYFIINILVRSAKKPQFFLSLYRMFGDIFSKRSV
                     YPQQFVQANTLLFHILLYLREQCMSEKEVKE"
     misc_feature    complement(1701..1717)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 22.81"
                     /tool="antismash"
     gene            1898..3253
                     /gene="ywhK"
                     /locus_tag="O6U12_RS19430"
                     /old_locus_tag="O6U12_19430"
     CDS             1898..3253
                     /codon_start=1
                     /gene="ywhK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391625.1"
                     /locus_tag="O6U12_RS19430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O6U12_19430"
                     /product="YncE family protein"
                     /protein_id="WP_017696255.1"
                     /transl_table=11
                     /translation="MRKNKLSFKEKAGAEQEECLCFCEGEASREAMFQAPIELSEGFVV
                     DPAEAVANVTWNADSLSCVSDRCLIQTGPEPDEVGVQFAVRLQGTVTLLVSVSPVRNQY
                     GQGDGAVSVIHNAEIDQVVYYSDEPDDCPDISDITIENLVVVPPFYGSPLSVTGTIVLV
                     PEPEPVYAFTANPNDQSVSVIDTNTHTVVTTIALPYNPAGIEITPDKSAVFVLHPNNNV
                     ISVIDYDTLTVTATILLDQPPRLIRFIPNHEFAYVFTGTAIYVIGIDTLTVERSIPVEG
                     FDIAIDPNGLFAYVLNFGLVQKVDLSTGEVLGTIERELIVSSIETDSTERYAYVLEQEF
                     LFNYLTVIDLNTFTIRDTQELEPDGLYVMFTSGSEVYLHDSFTGNLYSVSPNGAGVIGN
                     LPQSATDYAFTPNGDFLYATRFIEQSIIVYNTDDYSEETVISLGVSPGAITI"
     gene            3302..4669
                     /gene="ywhL"
                     /locus_tag="O6U12_RS19435"
                     /old_locus_tag="O6U12_19435"
     CDS             3302..4669
                     /codon_start=1
                     /gene="ywhL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391624.1"
                     /locus_tag="O6U12_RS19435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O6U12_19435"
                     /product="YncE family protein"
                     /protein_id="WP_017696256.1"
                     /transl_table=11
                     /translation="MDLSALQENCFCFCDEEISREAPFQVPIDIPEGFKVDSAEASAAV
                     TWSTDNVSCISEPCLIQTGPEPEDIGVRYAVRVQGTITLLVSVSPVRNQYGQGNGAVSV
                     IHTEEIDQVVYYAAQSGRCPDFSQITVEDLLIVPPFYGSPLTVTGTLVLPPSPDPQSYV
                     FTANTGDSTVSVIDADLNTVVKTIPFSDVPTNLGVTFDKAFTYVLHGNTNLVSVIDNKT
                     LTIINTITVGGGPRKIEFDPKDEFAYVMAAGSIYVINTASQSVIDVIPIPGALDFALDP
                     NGQYVYTANGSSWSVDKYDINTGQLVESIIDTFEFPSLIATPYAGNFAYVLNGELWPKG
                     VTEISLSPLSRGGDFSRLFETLRTIVFSLDSTRAYFLEPYSEPFLINNLYVVNTARQRI
                     IANVSLPGAFDLAVTPDKQYIYAAQPNDNAVTVYRTSDYTAVTVIPVGAGPSAIAM"
     misc_feature    complement(3309..3326)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 21.71"
                     /tool="antismash"
     gene            complement(4675..5376)
                     /gene="albG"
                     /locus_tag="O6U12_RS19440"
                     /old_locus_tag="O6U12_19440"
     CDS             complement(4675..5376)
                     /codon_start=1
                     /gene="albG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391623.1"
                     /locus_tag="O6U12_RS19440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O6U12_19440"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbG"
                     /protein_id="WP_017696257.1"
                     /transl_table=11
                     /translation="MKKSTVFTLLFLLIGMAAYSFGWVQAVAEAAAQYVQMINNDAVRL
                     GLLACTAALLMLPAFLYLHYVTQSVKNMTAAFQKLTQSHQSCCDFQQHNLCSRYAEDVK
                     SLRDSYKNVRQTYVMAAVLCQVIIFGCMFEIVKAVPFRLHTPPALSMGLAMLLILYLLF
                     CMRTYLRQLFRHGSLFRKVFAGALAAAGIWWMLSFSISELLFLIILATIQQIGSFIYKR
                     FSYRSTASLDL"
     gene            complement(5373..6653)
                     /gene="albF"
                     /locus_tag="O6U12_RS19445"
                     /old_locus_tag="O6U12_19445"
     CDS             complement(5373..6653)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="albF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391622.1"
                     /locus_tag="O6U12_RS19445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O6U12_19445"
                     /product="pitrilysin family protein"
                     /protein_id="WP_017696258.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 9.4e-13, bitscore:
                     46.4, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKAFFQQLDERTDIRYTDSGLKIFRLKFPRAHLRLCNVKIDFG
                     SRDVCIRAESGDTLLPYGTAHFLEHLLFWHNGRNLYSDFFAHGALLNAFTTYTDTNFMF
                     TSLPDRLRQTIPILLDALWNHSFDKKIVAQEKAVITSEIQTAHLNDQLSYHYQLISMLS
                     PSSPAAVFPAGRIEDIEALDISDLQKAYKAAYQTHRMTLFLIGGSENTETLLPPHLQLE
                     KRPDYHAERKIIPACPPALSQKMMLGDEERMEDTWTGLQIGALPGQNDLWVIKLYWDIA
                     ARILFQLDSPFFQEIQQTYRLEIDRLSAETYIYEDGGFLILHSQGTHSSAYIDVASYYV
                     TQKKEQVAAWLQYGKDSLTDAIIYDSDYVRKCFEWAAECDRCDCSFLDMYHIIQDMDAQ
                     VFLSLIDAMASSNKAIIHVSQKEAIRQ"
     gene            complement(6658..7818)
                     /gene="albE"
                     /locus_tag="O6U12_RS19450"
                     /old_locus_tag="O6U12_19450"
     CDS             complement(6658..7818)
                     /codon_start=1
                     /gene="albE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391621.1"
                     /locus_tag="O6U12_RS19450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O6U12_19450"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbE"
                     /protein_id="WP_080015532.1"
                     /sec_met_domain="Peptidase_M16_C (E-value: 5.6e-05,
                     bitscore: 21.2, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVNLLKTHQFSTISIAASFLKPIESAAEPEEETIYFYGAAAYLK
                     EQIIDAFGCAAGSRFMYSANLFFDQQLKTCGTRLIHPLYNGNLHVDALLKTFADLSFPS
                     SLSFEAVEKARNELLLRIEKKFTDPFSYSAARLAEEVFGNPMYGTGMFGRKDRIKAIHP
                     KRFLDATDFIVDLVSQQKQLNILGQVQACDVRGHAPQTSAVTSERIPVNRHVFETETRS
                     AAGPSVLTLGFDCGEMKDASDYIKIQLIDGLLGKYGHSALFKHFREKDLAVYHVITRYD
                     VMNNLLLVSICTDQLHEIDIPPRVLEAVSAFHTDERELEQAKQFLRNELLLQFDSPEGL
                     LAYMGILRRFSCTKEALLDGISAVTCRDVLQFIATINYIGAHVVRG"
     gene            complement(7808..9118)
                     /gene="albD"
                     /locus_tag="O6U12_RS19455"
                     /old_locus_tag="O6U12_19455"
     CDS             complement(7808..9118)
                     /codon_start=1
                     /gene="albD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391620.1"
                     /locus_tag="O6U12_RS19455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O6U12_19455"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbD"
                     /protein_id="WP_038829818.1"
                     /transl_table=11
                     /translation="MNNIIPIMSLLFKQLYSRQGKKDAIRIAAGLVILAVFEIGLIRQA
                     GIDESVLRKTYIILALLLMNAYMVFLSVTSQWKESYMKLSCLLPISSRSFWLAQSVVLF
                     VDTCLRRTLFFFILPLFLFGNGTLSGAQTLFWLGRFSFFTVYSIIFGVVLSNHFVKKKN
                     LMFLLHAAIFACVCISAALMPAATLPLCAVHMLWAVIIDFPVFLQAPPQQSKMHSFMRR
                     SEFSFYKREWNRFISSKAMLLNYAVMAAFSGFFSFQMMNTGIFNQQVVYIVISALLLIC
                     SPIALLYSIEKNDRMLLITLPIKRKTMFWAKYRFYSGLLAGGFLLVVMIVGFISGRPIS
                     VLTFLQCIELLLAGAFIRLTADEKRPSFSWQTEQQLWSGFSKYRSYLFCLPLFLATLAG
                     TAVSLAVIPIAGLVIVYYLQKQDGGFFDTSKRERLGS"
     gene            complement(9111..9830)
                     /gene="albC"
                     /locus_tag="O6U12_RS19460"
                     /old_locus_tag="O6U12_19460"
     CDS             complement(9111..9830)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="albC"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391619.1"
                     /locus_tag="O6U12_RS19460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O6U12_19460"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_017696261.1"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYERDNVILEQVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGRFTLCGIEAEAGMPQKTSDQLKTHRYFAADYPLLFTEITAKDYVS
                     FVHSLYQKDFSEQQFASLAEAFHFSKYINRRISELSLGNRQKVVLMTGLLLRAPLFILD
                     EPLVGLDVESIEVFYQKMREYCEAGGTILFSSHLLDVVQRFCDYAAILDNKQIQKVIPI
                     GEETDLRREFFEVIGHE"
     gene            complement(9827..9988)
                     /gene="albB"
                     /locus_tag="O6U12_RS19465"
                     /old_locus_tag="O6U12_19465"
     CDS             complement(9827..9988)
                     /codon_start=1
                     /gene="albB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391618.1"
                     /locus_tag="O6U12_RS19465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O6U12_19465"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbB"
                     /protein_id="WP_003222006.1"
                     /transl_table=11
                     /translation="MSPAQRRILLYILSFIFVIGAVVYFVKSDYLFTLIFIAIAILFGM
                     RARKADSR"
     gene            complement(10001..11347)
                     /gene="albA"
                     /locus_tag="O6U12_RS19470"
                     /old_locus_tag="O6U12_19470"
     CDS             complement(10001..11347)
                     /codon_start=1
                     /gene="albA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391617.1"
                     /locus_tag="O6U12_RS19470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O6U12_19470"
                     /product="subtilosin maturase AlbA"
                     /protein_id="WP_017696262.1"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1079.5, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 5.3e-29,
                     bitscore: 98.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.5e-07, bitscore: 28.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 2e-43, bitscore:
                     146.8, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 1.2e-05, bitscore: 22.8,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 7.1e-22, bitscore: 76.5,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 5.4e-10, bitscore:
                     37.5, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.7e-09, bitscore: 36.0,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIEQMFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLN
                     KTAYELCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQLGNRASR
                     HTITTSGSNEFPMPLHATFELTHCCNLKCAHCYLESSPEALGTVSIEQFKKTADMLFDN
                     GVLTCEITGGEIFVHPNANEILDYVCKKFKKVAVLTNGTLMRKESLELLKTYKQKIIVG
                     ISLDSVNSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKV
                     RDLGAKAFSYNWVDDFGRGRDIVHPTKDAEQHRKFMEYEQNVIDEFKDLIPIIPYERKR
                     AANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFNSPLVHKLWQAQAPRF
                     SEHCMKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     aSDomain        complement(11057..11332)
                     /aSDomain="Subtilosin_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a subtilosin
                     sactipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_O6U12_RS19470_Subtilosin_rSAM_RRE.1"
                     /evalue="3.40E-31"
                     /identifier="RREFam018.1"
                     /label="O6U12_RS19470"
                     /locus_tag="O6U12_RS19470"
                     /protein_end="97"
                     /protein_start="5"
                     /score="98.4"
                     /tool="antismash"
                     /translation="MFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLNKTAYE
                     LCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQ"
     gene            complement(11372..11524)
                     /gene="sboX"
                     /locus_tag="O6U12_RS19475"
                     /old_locus_tag="O6U12_19475"
     CDS             complement(11372..11524)
                     /codon_start=1
                     /gene="sboX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_054594.1"
                     /locus_tag="O6U12_RS19475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O6U12_19475"
                     /product="bacteriocin-like protein SboX"
                     /protein_id="WP_010886632.1"
                     /transl_table=11
                     /translation="MKLPVQQVYSVYGGKDLPKGHSHSTMPFLSKLQFLTKIYLLDIHT
                     QPFFI"
     gene            complement(11481..11612)
                     /gene="sboA"
                     /locus_tag="O6U12_RS19480"
                     /old_locus_tag="O6U12_19480"
     CDS             complement(11481..11612)
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="sboA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391616.1"
                     /locus_tag="O6U12_RS19480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O6U12_19480"
                     /product="subtilosin A"
                     /protein_id="WP_003222002.1"
                     /sec_met_domain="Subtilosin_A (E-value: 9.4e-29, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       complement(11583..11612)
                     /prepeptide="leader"
                     /note="peptide class: sactipeptide"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="O6U12_RS19480_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       complement(11481..11582)
                     /prepeptide="core"
                     /locus_tag="O6U12_RS19480_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="33.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[11582:11612](-)"
     misc_feature    complement(11703..11718)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 25.99"
                     /tool="antismash"
     gene            11925..12353
                     /gene="ywiB"
                     /locus_tag="O6U12_RS19485"
                     /old_locus_tag="O6U12_19485"
     CDS             11925..12353
                     /codon_start=1
                     /gene="ywiB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391615.1"
                     /locus_tag="O6U12_RS19485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O6U12_19485"
                     /product="DUF1934 domain-containing protein"
                     /protein_id="WP_017696263.1"
                     /transl_table=11
                     /translation="MKQETPITLHVKSVIEDDGNQEVIEFRTTGFYYVKQNKVYLSYYE
                     EHDLGKVKTIVKVSEGEVLVMRSGAVKMNQRFITGASTIAKYKMSFGELELKTSTKSIQ
                     SDLDEEKGRISIAYDMHVGDEQEHLHNMTITYEGGTHA"
     gene            12350..14020
                     /gene="argS"
                     /locus_tag="O6U12_RS19490"
                     /old_locus_tag="O6U12_19490"
     CDS             12350..14020
                     /EC_number="6.1.1.19"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391614.1"
                     /locus_tag="O6U12_RS19490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O6U12_19490"
                     /product="arginine--tRNA ligase"
                     /protein_id="WP_003227570.1"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLETPKDKTHGD
                     YSTNMAMQLARVAKKAPRQIAEEIVAHFDKGKASIEKLDIAGPGFINFYMNNQYLTKLI
                     PSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRF
                     VNEEESERLAFFREYGLKYELEKLRKDLENFRVPFDVWYSETSLYQNGKIDKALEALRE
                     KGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWG
                     ADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKP
                     AADLDFSHIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     misc_feature    complement(14076..14091)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     gene            14149..15336
                     /gene="narK"
                     /locus_tag="O6U12_RS19495"
                     /old_locus_tag="O6U12_19495"
     CDS             14149..15336
                     /codon_start=1
                     /gene="narK"
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391613.2"
                     /locus_tag="O6U12_RS19495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O6U12_19495"
                     /product="nitrate transporter NarK"
                     /protein_id="WP_015250995.1"
                     /transl_table=11
                     /translation="MINRQHIQLSLQSLSLVAGFMVWVLISSLISQITLDIHLSKGEIS
                     LVTAIPVILGSLLRIPLGYLTNRFGARLMFMVSFILLLFPVFWISIADSLFDLIAGGFF
                     LGIGGAVFSIGVTSLPKYYPKEKHGVVNGIYGAGNIGTAVTTFAAPVIAQAVGWKSTVQ
                     MYLVLLAVFALLHVLFGDRHEKKVKVSVKTQIKAVYRNHVLWFLSLFYFITFGAFVAFT
                     IYLPNFLVEHFGLNPADAGLRTAGFIAVSTLLRPAGGFLADKMSPLRILMFVFAGLTLS
                     GIILSFSPTIGLYTFGSLTVAVCSGVGNGTVFKLVPFYFSKQAGIANGIVSAMGGLGGF
                     FPPLILASVFQATGQYAIGFMALSEVALASFVLVIWMYWQERMKTHTERNSQSIN"
     gene            15434..16150
                     /gene="fnr"
                     /locus_tag="O6U12_RS19500"
                     /old_locus_tag="O6U12_19500"
     CDS             15434..16150
                     /codon_start=1
                     /gene="fnr"
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391612.1"
                     /locus_tag="O6U12_RS19500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O6U12_19500"
                     /product="fumarate/nitrate reduction transcriptional
                     regulator Fnr"
                     /protein_id="WP_003227573.1"
                     /transl_table=11
                     /translation="MNFLSVRPSDSDLISSDLHELLESISTKRKMEKHTYLFREGMDAE
                     ELYLIQSGLIEIGKLTSDGKDLTLRICQKHDIVGELTLFTEEPRYMLSAKVLEDGEVLV
                     INKNKLEKELIQNGALTFEFMKWMSTHLRKIQSKIRDLLLHGKKGALYSTLIRLSNSYG
                     VERSDGILINIVLTNQDLAKFCAAARESVNRMLGDLRKKGVISIDESGKIILHKRDYLR
                     CEIECENCPLEICNID"
     gene            complement(16182..16901)
                     /gene="ywiC"
                     /locus_tag="O6U12_RS19505"
                     /old_locus_tag="O6U12_19505"
     CDS             complement(16182..16901)
                     /codon_start=1
                     /gene="ywiC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391611.1"
                     /locus_tag="O6U12_RS19505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O6U12_19505"
                     /product="YwiC-like family protein"
                     /protein_id="WP_014481214.1"
                     /transl_table=11
                     /translation="MKALIPKQHGAWAMLLIPFLLGMVKGGPVIWHIPLFLGWLFLYLA
                     VYPVTLALKKKQSKPYQKWMCYYGFPACCFLMISVFHKPPLIWVGVSLLPLFLIHMYFA
                     RRKNERALLNDVAGVLFFCSGGFASCWLGMGTLDGWAWFIFLQSALFFIGSSFYVKSVI
                     RERKNRAFAYWSWGYHLLLPFLSALFGAGWAFLAFIPSSLRAWFFHGRDWPVKTIGILE
                     IVNACFFLAVMCLFITR"
     misc_feature    16972..16987
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            17045..17521
                     /gene="arfM"
                     /locus_tag="O6U12_RS19510"
                     /old_locus_tag="O6U12_19510"
     CDS             17045..17521
                     /codon_start=1
                     /gene="arfM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391610.1"
                     /locus_tag="O6U12_RS19510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O6U12_19510"
                     /product="Crp/Fnr family transcriptional regulator ArfM"
                     /protein_id="WP_003243032.1"
                     /transl_table=11
                     /translation="MNQCDYLLFLKQLPMFNEVPLSIVETLLKNGTFIRGSCDQSPSFL
                     HSQSVYIVLKGSVRFMDTRLPEGSKTVALWEKGDVFPIDEKGGLYLSPFISVNATSDIL
                     ILNIPYYIFKKMMSYHPQLQMNFLAMLQQNVFCSYQLFLRYLHTSQDENAEPGS"
     misc_feature    complement(17608..17622)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.64"
                     /tool="antismash"
     misc_feature    17609..17622
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.07"
                     /tool="antismash"
     misc_feature    complement(17631..17646)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     gene            17712..21398
                     /gene="narG"
                     /locus_tag="O6U12_RS19515"
                     /old_locus_tag="O6U12_19515"
     CDS             17712..21398
                     /GO_component="GO:0009325 - nitrate reductase complex
                     [Evidence IEA]"
                     /GO_function="GO:0008940 - nitrate reductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009061 - anaerobic respiration [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="narG"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134: flavodoxin"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391609.2"
                     /locus_tag="O6U12_RS19515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O6U12_19515"
                     /product="nitrate reductase subunit alpha"
                     /protein_id="WP_017696264.1"
                     /transl_table=11
                     /translation="MKKKKRSPLFRRLNYFSPIEHHSNKHSQTTRDDRDWENVYRNRWQ
                     YDKVVRSTHGVNCTGSCSWNIYVKNGIVTWEGQNLNYPSTGPDMPDFEPRGCPRGASFS
                     WYIYSPLRVKYPYVRGVLINLWREALQEHQNPLEAWKSIVENPEKAKSYKQARGKGGFV
                     RAEWPEVLKLISASLLYTVMKYGPDRNVGFSPIPAMSMISHASGSRFMSLIGGPMLSFY
                     DWYADLPPASPQIWGDQTDVPESSDWYNSGYIITWGSNVPLTRTPDAHFLAEARYKGAK
                     VISISPDFAESSKFADDWLSIRQGTDGALAMAMGHVILQEFYVNQETERFIEYAKQYTD
                     FPFLVTLSKENGVYTAGRFLHAKDIGRKTKHDQWKPAVWDEQTSSFAIPQGTMGSRWDG
                     QQKWNLHMIDEETGEPIEPRLSVLGIEDEIGTVRIPYFSNDGNKVLERDLPIKKMNLNG
                     EETYVTTVFDLILANYGVNRGIGEQQAVSYDDPEPFTPAWQEQMTGIKKEAVVKIAREF
                     AQNAIDTDGRSMIIVGAGINHWFNSDTIYRAVLNLVLLVGAQGVNGGGWAHYVGQEKLR
                     PAEGWQTIATAKDWEGVPKLQNGTSFFYFATDQWRYEDQPISDLASPIAASSRYKHHAD
                     YNVLAARLGWLPSYPTFNQNGIDLYKEAEKAGAATPEDVGAYVASQLQEKKLKFAIEDP
                     DNEVNFPRNLFVWRANLISSSGKGHEYFLKHLLGTTNGLMNDDSDSIRPEEIKWREQAP
                     EGKLDLLINLDFRMAGTALYSDIVLPAATWYEKHDLSSTDMHPFIHPFAPAISAPWESK
                     SDWDIFKALSKAVSDLAEEVNMEPVKEVVATPLLHDTMQELAQPFGKINDWSKGECEAI
                     PGKTMPNIQVVERDYKHIFHKMTALGPNAALKPSGTKGMSWSIADEYESLKKRLGEITS
                     DSVAKGCPNISEAKQAAEAVLTLSSTSNGKVAVKAWESLENITNLKLKDLAEEREEECF
                     TFEQITAQPKTVITSPAFTGSEKGGRRYSPFTTNVEKLIPWRTLTGRQSYYVDHELMME
                     FGETMATFKPILQHRPFLSKRPDQEGKEIVLNYLTPHNKWSVHSMYFDSLPMLTLFRGG
                     PTVWMNKDDAEDTDIKDNDWIECFNRNGVVVARAVLSHRIPKGMAFMHHAQDRHINVPG
                     TKLTNNRGGTHNSPTRIHVKPTQMIGGYAQLSYGFNYYGPTGNQRDLNVVIRKLKEVDW
                     LED"
ORIGIN
        1 catgagccaa cccaaatggg caaacacctc caatttcatg gcctgtctgc tccagtacct
       61 cattaggaga gagcactctt gctttaaagc caaatgtttg cctgaacttt ttgttattaa
      121 tcttggcatc gccggctgcc acaatcagaa tcgcctgatc tcctacccct ctgaaggaca
      181 gggtcttggc gattctagtc gggcttacgc cgatcgtctc agctgtctgt tcaacactgt
      241 cgcgctcgac gtctcgaact ccgtcacatc attttctcga ttccactgtg taaagtgggt
      301 tctcacactt tttagagaca tgctgcattt ccactatttt taagattatt gaaaaaatca
      361 tagcatggat tgggagactg ggtaaagagg ggacaaaaaa accgccgatg gacggcggtt
      421 tagatcatgg cgcgttgcgc aacatcaaaa tgttctgttg atgaatttga tacttcgact
      481 gtgataaata cagcactcac agctaaacaa gcgagtaata atttatactt ccatttcata
      541 taaattcacc cccccttgaa tgtgctgtct tgcttcttca acctttaaaa agtaatgaga
      601 tgcttttttg taattttcct gttgatgata atatttagca acatcaagtg cgaagtcctc
      661 aatatctgca tacatcattt tactttcaag aaaaacaaaa catttttcta tccgttcctc
      721 atccggtcca gacaagtata aagattccaa aaattcaaac tccgttagat acacggtatc
      781 tcccgcagct gcagaatact cttttccttt tttatgatat tcacaggcgt tatcaatctt
      841 acctaattta aaataaattt gtgtaattag gaaaaaagct tgtggcaatg aaggaagcat
      901 tttagatcct tcaaatactt gaatagattt ttttacatac tctatcgctg attcaaaact
      961 gttttggttt tgcttgcaga gtgctatgtt ataaagtgtt cttcccatta attggggctg
     1021 ctgctctgtt tttgcaagtg taaaggcttt ttgaaaatgg gcaattgctt tttcgtattg
     1081 ttttaaatcc aaaaagttgg ctccgaataa ggactggcat tgaatcattc tgatatcata
     1141 tgtagtctgt tcactgtata tttcgaatgc ttgacgtgca tagtccatgg agacataagt
     1201 ttgtttcata taataataga cttctgacat tttgaaaaag aattcagctt tatcgatttt
     1261 atctttgaca aaaaccagct tgctctcagc ttttttaaag aattgaatgg ctaatacata
     1321 ttcacggcga tccagctcat acatgcctct gaagaaatta aaatagtact caagcagacc
     1381 agttaaacga gcctgttttt tatcaatctc aagcagcaga tcagacagtc tcggctgttc
     1441 ctcaatcctc attttttcta acggttcaag gtactcaagc atcaggttgt gccgaaactc
     1501 catcagtgaa tagtacaaat gaaggtcttg atcttcttcc atttgatcca gctcttgctt
     1561 gatttctcgt cgcaaatatt ctgcatcggg tatgctaaat cggcgtatgt acatatacca
     1621 ttcgttaatc ttttctccga tggaagaaga agatatgaca cctgtcactt ttgcaaatcc
     1681 ctcccttcat aattctatat atgtcatatt ttatcatcaa cattcttgtg agaagcgcaa
     1741 aaaaaccgca attttttctt tcgttatacc gcatgtttgg agatatattt tcaaaaagaa
     1801 gcgtttaccc tcagcaattt gtacaagcaa acacgttact cttccatatt ctgttatatc
     1861 tgcgtgagca gtgtatgtct gaaaaggaag tgaaggaatg agaaaaaata agctttcctt
     1921 taaagaaaaa gcaggagcag aacaagaaga gtgcttatgt ttttgtgagg gagaagcaag
     1981 ccgagaagcc atgtttcaag cgccgattga attatctgaa ggatttgtcg ttgatccggc
     2041 tgaagctgtt gcaaacgtga cgtggaatgc agacagcctt tcttgtgtca gtgaccgttg
     2101 cttaattcaa acggggccag agcctgatga ggtcggtgtt caatttgcag tgcgcctgca
     2161 gggaaccgtt acgctactcg tcagtgtctc acctgtgcga aatcaatatg gacaagggga
     2221 cggggctgtt tccgtcattc acaatgcaga aatcgatcaa gtcgtctatt attccgatga
     2281 accggatgat tgcccggata tcagtgacat cacgattgag aaccttgttg ttgttccgcc
     2341 gttttacggc agtcctttat cggtgacggg gacgattgtg cttgtaccgg agccggaacc
     2401 cgtctacgcg tttacagcga atccaaatga tcaatcagtt tctgtgattg atacaaacac
     2461 ccatactgtt gtgacaacga ttgctcttcc gtacaatccg gcaggtattg aaattacgcc
     2521 agataaaagc gctgtgtttg tcttacatcc caacaataat gtgatttctg tcatcgatta
     2581 tgacacatta acagtgacag caactatatt gctggatcag ccgcctcgat tgattagatt
     2641 tatccctaat catgagtttg cttatgtttt caccggtact gccatttatg tgattggaat
     2701 tgatacgttg actgttgaga ggtctattcc tgtagaaggt tttgatattg caattgaccc
     2761 caatgggttg ttcgcctatg ttcttaattt tgggttagtg caaaaagtgg acttatctac
     2821 cggtgaagtc ttaggaacga ttgaacgaga gcttatcgta tcatccatag aaacagattc
     2881 tacggagcgg tatgcgtatg tattagaaca agaattctta ttcaattatt tgacggttat
     2941 tgatttaaat acgtttacga tcagggatac ccaagagctg gagcctgacg ggctatatgt
     3001 aatgtttacg agtggatcag aggtgtattt acatgacagc ttcactggca atttatattc
     3061 tgtcagtccg aatggagcag gtgtaattgg aaatcttccg caatcagcaa cagactatgc
     3121 gtttaccccg aatggcgatt ttctgtatgc aactcgtttt atagagcaga gcatcattgt
     3181 ttacaacaca gatgattatt ctgaggaaac tgtgatatct cttggggttt caccgggtgc
     3241 cattacgatt taaccgctgc atgttgtgca tttctaaaag gacgtgaaat catgaaaaag
     3301 aatggatctt tctgctttac aggaaaattg tttctgtttt tgtgatgagg aaattagccg
     3361 agaagcgccg tttcaagtgc cgatagatat ccctgagggc ttcaaggttg attcggccga
     3421 agcgtcagcg gctgttacat ggagtacaga caatgtgtcc tgtatcagtg agccttgctt
     3481 aatccagact gggccggaac cagaagatat cggtgttcga tatgctgtga gagtacaagg
     3541 gaccattacg cttcttgtca gtgtgtcgcc tgtgcgaaat caatatggac aaggcaatgg
     3601 ggcggtttct gtgattcata ccgaagagat tgatcaagtt gtttattatg cagcacagtc
     3661 tggccgctgt cctgatttca gtcaaataac agtggaagat ctgctcattg taccgccttt
     3721 ctacggcagt ccgcttacgg tgaccgggac acttgtttta ccgccatcac cagaccctca
     3781 atcgtatgtg tttactgcca atactggaga cagcacggtt tcggttattg atgcagattt
     3841 aaacactgtt gtaaaaacaa tccctttttc tgacgtgcca actaatctag gcgttacttt
     3901 cgataaagca ttcacgtatg tcctccatgg aaataccaac cttgtctcag tgattgataa
     3961 taaaacatta accatcataa ataccattac tgttggagga gggccgagaa agatcgaatt
     4021 tgatccaaaa gatgagttcg catacgtgat ggccgccgga tctatatatg tgattaacac
     4081 ggcctctcaa tcggtcattg atgtcattcc gatacccggc gctttagact ttgctcttga
     4141 tccgaatgga cagtatgtct ataccgctaa tggaagcagt tggtcggttg ataaatatga
     4201 tataaatact gggcagttgg tagaaagtat catagataca tttgaatttc ccagtttaat
     4261 tgcaactcct tacgctggaa attttgcgta cgtgttgaat ggtgagctgt ggccgaaagg
     4321 tgtaacggag attagtttgt ctccattaag caggggaggg gacttcagcc gtttatttga
     4381 aacgctgagg acgattgtat tttctctcga tagcactaga gcttattttc tagagccata
     4441 tagtgaaccg tttcttatta ataacttata tgtagttaat acggccagac agaggatcat
     4501 tgcaaacgtg tctctccccg gcgcttttga cctcgccgta acgccggaca aacagtatat
     4561 ttatgcggca cagcccaacg acaatgctgt gaccgtgtac cgcacaagtg attatacagc
     4621 cgtgacggtg attccggttg gcgcgggtcc gtctgcgatt gcgatgtagc tattttatag
     4681 atcaagagaa gcggtgctgc gataagagaa tcgtttataa ataaatgatc cgatttgctg
     4741 aatggtagcc aggataatca gaaacagcag ttcacttata gagaaactga gcatccacca
     4801 aatcccggct gctgccagcg ctcccgcaaa cacttttctg aacaggctgc cgtgccggaa
     4861 aagctgccgc aaataagttc gcatgcaaaa caataaatac agaatcagta gcatcgcaag
     4921 tcccattgaa agggcagggg gcgtgtgaag gcggaaaggg acggctttaa cgatttcgaa
     4981 catgcagccg aatatgatga cttggcacaa cacggcagcc atcacgtatg tttggcggac
     5041 gtttttatag ctgtcacgca gcgatttgac gtcttctgca tatcggctgc acaagttgtg
     5101 ttgctgaaag tcacagcagc tttgatgaga ctgtgtgagt ttctgaaaag ctgctgtcat
     5161 gtttttcacg gattgggtga cataatgaag atatagaaaa gcaggcagca tcaggagggc
     5221 agcggtacaa gccagcagtc cgagccgaac agcatcattg ttgatcatct gtacatattg
     5281 ggcggcggct tcggcaacgg cctgaaccca tccgaaggaa taagccgcca tacctataag
     5341 cagaaataaa agggtaaaga cagtgctttt tttcattgtc tgatcgcctc tttctgagaa
     5401 acgtgaatga tcgctttgtt agaagatgcc attgcatcaa tgagagacaa gaaaacctgc
     5461 gcatccatat cttgaatgat gtggtacatg tcaagaaacg agcaatcgca cctgtcacac
     5521 tcggctgccc actcgaagca tttacgcaca taatcgctgt cataaatgat cgcgtctgtc
     5581 aaagagtcct tgccgtattg aagccaggcg gcaacctgtt ctttcttctg tgtgacatag
     5641 tatgaagcca catcgatata agctgaagaa tgggtccctt gactgtgaag gatcaagaaa
     5701 ccgccatcct catatatata agtctcggct gacaagcgat cgatttccag acggtacgtt
     5761 tgctgaatct cttgaaaaaa cggtgaatct aattgaaata gaatacgagc cgcgatatcc
     5821 caataaagct ttatcaccca cagatcgttt tgcccgggaa gtgcgccgat ctgtaatccg
     5881 gtccatgtat cttccatccg ctcctcatca cccagcatca ttttttgtga gagggctgga
     5941 gggcatgccg ggatgatttt tctttcagca tgataatccg gacgcttttc cagctggagg
     6001 tgaggaggca aaagcgtttc tgtattttct gagcccccaa tcaaaaacag cgtcatccga
     6061 tgggtttggt aggcagcctt ataggctttt tgtaaatcac tgatgtccag cgcctcaata
     6121 tcttcgattc tgcctgcggg gaaaacggca gctggtgagg agggagaaag catgctgatc
     6181 agctgataat gatatgagag ctgatcgtta aggtgtgctg tttgaatttc gcttgtaatc
     6241 acagcttttt cctgagcgac aatcttcttg tcaaatgagt ggttccataa agcatcaagc
     6301 aggatgggga tcgtttgtct gagccgatcc ggtaatgagg taaacatgaa attggtatcg
     6361 gtgtaggtag tgaatgcgtt taaaagcgcg ccatgcgcaa aaaaatcact gtacagattg
     6421 cggccgttat gccagaagag aagatgctct aaaaaatgcg ctgtgccata cggaagcagt
     6481 gtatcaccgg attctgcccg tatacataca tcccggcttc caaaatcgat ttttacattg
     6541 cacagccgca ggtgggcgcg ggggaatttc aatctgaata tttttagtcc gctgtctgtg
     6601 tatctgatat cggttcgttc atccagttgt tgaaaaaagg ctttattttc catctcttca
     6661 tccccttact acatgagctc cgatataatt gatggtcgct atgaattgca atacatcacg
     6721 gcatgtaacc gctgagatgc catccagcaa ggcttctttc gtgcaggaga agcggcgcag
     6781 gatccccata taggccaata gaccttcggg agaatcgaat tgcagcagca attcattgcg
     6841 taaaaactgc tttgcctgtt ctagttcccg ctcatctgta tgaaaagctg agacagcttc
     6901 caaaacgcgc gggggaatgt ctatctcatg aagctgatct gtacatattg aaacaagcag
     6961 caaattgttc atgacatcgt aacgggtgat aacgtgatag actgccagat ccttctctct
     7021 gaagtgcttg aataaagcgg aatggccgta ctttcccagt aatccgtcta ttagctgtat
     7081 tttgatataa tcgctggcat ctttcatctc tccgcagtca aatccgagtg tcaagacgga
     7141 aggacctgca gcgctgcgtg tctctgtttc aaaaacatgc cggtttacgg gtattctttc
     7201 ggacgttaca gcggacgttt gcggggcatg tccccgaaca tcacatgctt gtacttgtcc
     7261 caatatgttc agctgttttt gctgggacac taaatcaacg ataaagtccg ttgcgtcgag
     7321 aaaccgttta ggatgaatcg cctttatcct gtctttccgg ccaaacatgc ctgtgccgta
     7381 catcgggttt ccgaagacct cctcagccaa gcgcgccgcc gagtaggaga aaggatcagt
     7441 gaatttcttt tcgattctca gcagcagctc attcctggcc ttttcaactg cttcgaatga
     7501 aagagaagaa gggaaagaca agtctgcaaa agttttcagc agggcgtcaa catgaagatt
     7561 cccgttatat aatgggtgaa tcaaacgggt cccgcaggtt ttcagctgct gatcaaaaaa
     7621 gagattcgct gagtacatga aacggctgcc ggcagcacaa ccgaaagcgt caataatttg
     7681 ctccttcagg tatgcggcgg cgccgtaaaa ataaatcgtt tcttcctcag gttccgccgc
     7741 gctttcgatc ggtttcagaa agctcgcggc gattgaaata gttgaaaatt gatgagtctt
     7801 cagcaggtta acttccaagc cgttctcttt tgcttgtatc aaagaaacca ccatcctgtt
     7861 tttgcaggta atagactatg accagaccgg ctatcggaat gaccgccaag gatacagcgg
     7921 tgccggctaa tgtggctaag aataggggaa gacaaaacag ataagaccga tattttgaga
     7981 aaccgctcca tagctgctgc tccgtctgcc agctgaagga gggccttttt tcatccgcag
     8041 ttaacctgat aaaagctccc gccagcagca actcaatgca ctgcaaaaaa gtgagaactg
     8101 aaatcggacg gccgctgatg aaacccacaa tcatcacgac aaggagaaat ccgcctgcca
     8161 ataggcctga ataaaagcga tatttcgccc aaaacatcgt tttccgcttg atcggaagcg
     8221 tgataagcag catccggtca tttttttcaa tcgaatacaa aagggcgatc ggcgagcaga
     8281 tgagcaaaag cgcggaaatc acgatataaa ccacttgctg attgaagatg ccggtattca
     8341 tcatctggaa cgaaaagaag ccgctgaacg ccgccattac cgcgtaattt aacagcatcg
     8401 ctttagaaga gataaatcgg ttccattctc ttttgtaaaa cgaaaattca gatcgccgca
     8461 taaatgaatg catcttgctc tgctgcggag gcgcctgcag aaagacagga aagtcaatga
     8521 tcaccgccca cagcatatgc accgcgcaaa gcggaagcgt ggcggccggc atcaaagcgg
     8581 cgctgataca tacacaggcg aatatcgccg catgcagcag aaacatcaag ttcttctttt
     8641 tgacgaagtg gttgcttagc acaactccga aaataatgga gtaaacggta aaaaacgaaa
     8701 acctgccgag ccaaaacaat gtttgcgccc ctgacagcgt tccgtttcca aataagaaca
     8761 gcggtaaaat aaaaaagaat aaagttcttc tcaaacaggt atcgacaaac aaaacgacac
     8821 tctgggcgag ccaaaagctc cgtgaagaaa tcggcagcag gcagctcagt ttcatataag
     8881 attccttcca ttgagatgtc acagaaagaa acaccatata tgcgttcatt aagagaagcg
     8941 cgagtatgat atacgttttg cgcaacaccg attcatcaat gccggcctgg cgaatcagcc
     9001 cgatttcaaa cacggccaga atgacaaggc ctgcggcaat gcggatggcg tcctttttcc
     9061 cttgccggct gtaaagctgt ttgaacagca aagacatgat ggggattatg ttattcatgg
     9121 ccgatcacct cgaaaaattc ccgccgcaga tcggtctcct ctccaatcgg aatgaccttt
     9181 tggatctgtt tgttgtcaag aatagccgcg taatcacaaa atctttgcac gacatcgagc
     9241 agatgagaag aaaacaaaat ggtcccgcct gcttcacagt actcgcgcat tttctgataa
     9301 aagacctcta tcgattccac atccaaaccg acgagcggct catccaaaat aaatagggga
     9361 gcgcgcagca ataagcctgt catcaataca accttttgcc tgttccccaa ggacagctcc
     9421 gaaattctcc tgttgatgta tttcgaaaaa tgaaaggcct cggccaaact ggcaaactgc
     9481 tgctctgaaa aatccttttg ataaagcgaa tggacgaaag acacatagtc cttcgccgta
     9541 atttctgtaa atagcagcgg ataatcggcg gcgaagtaac ggtgagtctt cagctgatct
     9601 gatgttttct gcggcatgcc ggcctccgct tcaattccgc acagtgtaaa gcgcccgctg
     9661 aaattgcggt tcacgcctgt cagcgtatta atcagtgtcg tttttccggc gccgtttacc
     9721 ccaagcaacc cgtaaacggc gcctttttct aaatgtaaat ctacttgttc taagatgacg
     9781 ttgtcccgtt cataccaaac ggatacatcg tgtatatcca aaatgctcat cgcgagtcag
     9841 ccttccgcgc gcgcatcccg aacagaatgg caatggcaat gaaaatcagc gtaaacagat
     9901 aatcgctttt gacaaaatag acgactgcgc cgatgacaaa gataaatgaa aggatataca
     9961 gtaaaattct tctttgtgct ggtgacaaat cgtttccctc ctaaataagc tggaccacgt
    10021 cttctaattg ttcatttttc gcccaagagc aaatgttttt tcggtgatat ttgttagagt
    10081 tcagcccttt taagtaacag cctccgcaat agccgctgaa cgggcatttg tctttcatgc
    10141 aatgttcact gaagcgcggc gcctgcgctt gccacagttt atggacgaga ggggagttaa
    10201 agatgctttc ataggaatca tgaaaaatat ttcccaatga aaattccttt ggaaagaggg
    10261 cgcaaggacg tacttcgccg aacgggctga tcacaatgga cttccagcca gcgccgcaat
    10321 ttgccgcgcg ttttctctca tagggaataa tcggaatcag atctttaaac tcatcaatca
    10381 cattttgctc gtattccata aacttgcggt gctgctcggc gtctttcgtt ggatggacaa
    10441 tatccctgcc tcttccgaaa tcgtcaaccc aattgtaaga aaatgccttc gccccgagat
    10501 cccgaacctt ttgggccata tcgtggattt cccacatgtt tttttcgaag acagacatgg
    10561 cgactctgac aaatataccg tggtcactca acaattttat cgttttacaa gtttgggcaa
    10621 aagagccttt tctccctcta aaggagtcat ggacctcgga attgacacta tcaagagaaa
    10681 tgccgacgat gattttttgc ttgtaagtct tcaaaagctc caggctctct tttcgcatga
    10741 gtgttccgtt tgttaagaca gcgacttttt tgaacttttt acacacatag tcaagaatct
    10801 cattggcgtt tggatggaca aaaatttctc cgcctgtgat ttcgcatgtc aatacaccgt
    10861 tatcaaacag catatcagcc gtttttttga attgctcaat cgacacggtg ccgagcgctt
    10921 caggtgagct ttccaaataa cagtgggcgc atttcaaatt acagcagtgc gtcagttcaa
    10981 aggtggcgtg caggggcatc ggaaattcat tgcttccgct cgtggtgatt gtatggcggc
    11041 tggcccggtt tccaagctgg atcacctgct tgttctggag catgttgagc atgtcgtaat
    11101 accaatcttt atggtcttcc ggtgattcat catacactgc acattgctca gctaaaatct
    11161 gctcagctgt tttttggcca tccatgcgca tgcagagctc gtaagccgtt ttgttgagat
    11221 ccaaatactc aaagtcagaa atggagacat tatcgcgcaa gtagtcgatt tctaacacgc
    11281 cgccctcagg aagctggtga actcttacac tttcattaat aaatggaaac atctgctcta
    11341 taaacaaaat accatcccct atacatatga ttcaaatgaa aaacggttgt gtatgtatat
    11401 ccaagaggta gattttagtt aaaaattgta atttacttaa aaagggcata gtagaatgac
    11461 tatgcccttt tgggagatcc ttacccccat agaccgaata gacctgttgc accggcaatt
    11521 tcaaaatcag ggataggacc gtccactaga caagcggctc cgatcgagca tgttgcacaa
    11581 cctttgtttt ctacaatgac agcttttttc ataattgaat cctccctttt tttgtttttc
    11641 tagcagatct atgttgtact tttatcttaa aactatcaaa ttactaattc aatacatata
    11701 ttttgaaaaa aatgtgaaaa ggaaatgata gatttcggaa aaatgtaaca tttcctaaag
    11761 gtaattagtg atatgatttt ctcttctata taaggaaatg ctttttatga ggtttatctt
    11821 caaatctgat gagcaatgat ggtaagatag aagcagttga agtttacaaa ccgaatgatt
    11881 atactattca agtcaaagtg gaatgatgaa aaggacgtgt cagaatgaag caagagacac
    11941 cgataacact ccatgtgaag tctgtgatcg aggatgacgg aaaccaagaa gtcatcgaat
    12001 tccgcaccac cggattttac tatgtaaaac aaaataaagt gtatctatct tattatgaag
    12061 aacacgactt aggcaaagtc aaaacgattg tgaaagtaag cgaaggcgaa gtcctggtca
    12121 tgaggtcagg ggctgtcaaa atgaatcagc gtttcataac gggagcttcc acaattgcta
    12181 aatataaaat gtcatttggt gagcttgagc tgaaaacaag cacaaaatcg attcaatctg
    12241 atctcgatga agaaaaaggc cgtatcagca tcgcatatga catgcatgtc ggagacgagc
    12301 aggagcattt acataatatg acgatcacgt atgagggagg aactcacgca tgaacattgc
    12361 ggaacaaatg aaggacgtgc tgaaagaaga aatcaaagcg gccgttctga aagcgggact
    12421 ggctgaagaa agccagattc ccaatgttgt tttagaaaca ccgaaagata aaacacacgg
    12481 cgactactca acgaatatgg cgatgcagct ggcaagagtg gcaaaaaaag cgccgcgtca
    12541 aatcgctgaa gagattgtcg cccattttga taaagggaag gcttcgattg aaaaactgga
    12601 tatcgccggc ccgggtttta tcaatttcta tatgaacaat cagtatttaa caaagctgat
    12661 tccgtctgta ctggaagcag gggaagcata cggggaaacg aacatcggaa acggtgaacg
    12721 agttcaggta gaattcgtat cagcgaatcc gacgggagac cttcacctcg ggcatgcgcg
    12781 cggggcggct gtcggcgatt ccttgtgcaa cgtgctttca aaagcgggtt acgatgtaag
    12841 ccgcgaatac tacattaacg atgcgggaaa ccaaatcaac aatctggcgc tctctgttga
    12901 agtccgttac tttgaagcac tcggattgga aaaaccgatg ccggaggatg gctaccgcgg
    12961 cgaggatatc attgcgatcg gaaagcgtct cgctgaggaa tacggtgatc gtttcgttaa
    13021 cgaagaggaa agtgaacgtc tcgcgttttt ccgtgaatac ggcctgaaat acgagctgga
    13081 aaagctgcgc aaggacttgg aaaacttccg tgtgccgttt gatgtgtggt attcagaaac
    13141 ctcactgtac caaaatggaa aaatcgacaa ggcgcttgaa gcgctccgcg aaaaaggcca
    13201 tgtctatgaa gaagacggcg cgacttggtt ccgttccacg acgttcggcg atgataaaga
    13261 ccgcgtattg atcaagaagg acggcacgta cacgtacctg cttcctgata tcgcgtatca
    13321 taaggacaag cttgaccgcg gctttgataa gctgatcaac gtttggggcg ccgatcacca
    13381 cggctacatc ccgcgtatga aagcggcaat cgaagcgctg ggctatgaaa aaggaacgct
    13441 tgaagtagaa atcattcagc tcgttcacct ttacaaaaac ggcgagaaaa tgaaaatgag
    13501 caaacggacc ggtaaagccg taacgatgcg tgacctgata gaagaagtcg gcttggatgc
    13561 cgttcgttac ttctttgcga tgcgaagtgc ggacacccat atggattttg acttagatct
    13621 tgctgtatca acatctaacg aaaaccccgt gtattatgca caatacgcgc atgcccgtat
    13681 ttgcagcatg cttcgccaag gggaagagca gggacttaaa ccggcggcag atcttgattt
    13741 cagccatatt caatcagaaa aagaatacga tctgctgaaa acgatcggcg gcttcccaga
    13801 ggcagtggcg gaagcagcgg aaaagcgaat tccgcaccgt gtcacaaact atatttatga
    13861 tctggcttct gctctgcaca gcttctacaa cgcagagaaa gtcatcgacc ctgaaaatga
    13921 agagaaaagc cgcgcgcgcc tggctttaat gaaggcaacg caaattacgc tgaacaatgc
    13981 gcttcagctg atcggcgtat cggctccgga aaaaatgtaa tcacgaacaa aaggacaaag
    14041 tcttcgggct ttgtcctttt tttatgagaa aaacgtgtga tgtaattcac aatcctgttt
    14101 gccgagtttt tgtatgataa gactgaatca ttgaaagggg caagccaaat gatcaaccgt
    14161 caacacattc aattatcgtt acagtcatta agcttggtgg cagggtttat ggtttgggtg
    14221 ctgatttcat cactcatttc ccaaatcaca ttagatattc atttaagcaa gggtgagatt
    14281 tctttagtga ccgcgattcc tgtgatcctc gggtcgcttc tccgcattcc tttagggtat
    14341 ttaacgaaca ggtttggcgc gcggctcatg tttatggtca gcttcatcct gcttttattt
    14401 cctgtatttt ggatcagtat cgcggattct ctgtttgatt taatcgcagg cggctttttc
    14461 ttagggatcg ggggagcggt gttttccatt ggggtgacct ccctcccgaa atattatccg
    14521 aaagaaaagc acggtgtcgt caatgggatt tacggtgcag gaaatatcgg gacagccgtt
    14581 acgacatttg cagcgccggt tatcgctcaa gccgtcgggt ggaaatcaac cgtgcagatg
    14641 tatttggttt tgctagctgt ctttgcctta ctgcacgttt tgtttggcga caggcatgag
    14701 aagaaggtca aagtttctgt taagactcaa atcaaagccg tttaccgaaa tcatgtgcta
    14761 tggtttctga gcctgtttta ttttattacg ttcggtgcct ttgtcgcctt cactatctat
    14821 ctgccgaact ttctggtgga gcattttggg ctgaatcctg cagatgccgg cttgcggacg
    14881 gctggcttta ttgcggtttc tacgctgctc aggcctgcgg gcggattcct ggctgataaa
    14941 atgagcccgc tccgcatctt gatgtttgtt tttgccgggc ttacattatc aggcattatc
    15001 ctatcgttct cgccgacaat cggcctttat acgtttggat cattaactgt ggccgtctgc
    15061 tcaggcgtag gaaatgggac tgtttttaaa ctggtgcctt tctatttttc gaagcaagcg
    15121 gggattgcca atgggattgt gtctgccatg ggcggattag gcggcttttt tcctccgctc
    15181 atattggcga gtgtgtttca ggcaacaggc cagtacgcga tcgggtttat ggcgctttca
    15241 gaggtggcgt tagccagttt tgtccttgtc atatggatgt attggcagga aagaatgaaa
    15301 acacacacgg agagaaacag ccagagcatc aactaacact gggcattcac aagattgtta
    15361 gttttttctc gatgggtaca aatcaattca cgttacaata aacacacaac gtgactttct
    15421 tcgaggtgag ctcatgaatt ttctctctgt tcgaccatct gatagtgatc ttatatccag
    15481 cgatctgcat gaactgctgg aatcgatcag cacgaaaaga aaaatggaaa aacacacgta
    15541 tttgtttcga gaaggaatgg atgcagaaga gctttatctg attcaatcag gactcattga
    15601 aatcggcaag ctgacatctg acggaaaaga cctgacgctt agaatctgcc aaaagcatga
    15661 tatcgtcgga gaattaacac ttttcactga agaaccgagg tatatgctca gtgcaaaagt
    15721 gctagaggat ggcgaggtgc tcgtcattaa taaaaataag ctggaaaaag aattaatcca
    15781 aaacggcgct ttgacatttg agttcatgaa atggatgagc acgcacctcc ggaagattca
    15841 gtccaaaatc agggatctgc ttcttcatgg caaaaagggg gcgctctatt ccacccttat
    15901 ccgtttatca aacagctacg gagtggagcg aagcgacggc attctgatta acattgtcct
    15961 gacaaatcag gatttggcaa agttttgcgc ggctgcacgg gaaagcgtca atcgtatgct
    16021 cggagatctc cgcaaaaaag gggttatttc gatagacgaa tccggaaaaa ttattttgca
    16081 caagcgggac tatttacgat gtgagattga gtgtgaaaat tgcccgctgg agatttgcaa
    16141 tattgactga aaaaaacaag gacagcggtg tccttgtttt tttaccttgt gataaacagg
    16201 cacatgacgg caagaaagaa gcaggcattc acgatttcca gaatgccaat cgtttttacg
    16261 ggccaatccc ttccatgaaa aaaccatgcc cgcaagctgc tcgggataaa agcgagaaac
    16321 gcccatcctg ctccgaaaag agcggataaa aaggggagca gcaggtgata tccccatgac
    16381 cagtatgcaa atgccctgtt ttttctctcg cggatcaccg atttcacata aaaggaactc
    16441 ccgataaaaa ataaagcaga ctgcaagaaa ataaaccaag cccagccgtc aagggttccc
    16501 atccccagcc agcagctcgc aaacccgccc gaacaaaaga acaagacacc tgcaacatca
    16561 ttcaataagg ctcgttcgtt ttttctgcgg gcaaaataca tatgtatgag aaacagcggc
    16621 agtaaagaaa cgcccaccca gatgagaggc ggcttatgaa agaccgagat catcaaaaag
    16681 cagcaggcgg gaaaaccgta ataacacatc cacttttgat atggtttgct ttgtttcttt
    16741 tttaaggcaa gcgtaacggg ataaaccgct aagtatagga aaagccaacc aaggaagagc
    16801 ggaatatgcc aaataacggg gcctcccttg accatgccga gtaaaaatgg gatcagcagc
    16861 atcgcccacg ccccgtgctg cttcggaatc agcgccttca tcgaaatcct ccttttttct
    16921 ttcattataa atgcattcac cctcctgata agtgacattc atcatacagg ctgtgaaata
    16981 catcactgct gtacaggctc agtcgagcta cactaaagct atccttagca caggaggttt
    17041 tcctatgaat cagtgtgact atttattatt tctgaaacaa cttcctatgt ttaatgaagt
    17101 gcctctatcc attgtcgaaa ccttgctgaa aaacggcacg tttatccgcg gttcgtgtga
    17161 tcagtctcca tcttttcttc attctcaatc tgtttatatt gtattaaaag gcagtgtccg
    17221 ttttatggac acaaggctcc ctgaagggtc gaaaaccgtt gcgctgtggg aaaaaggcga
    17281 tgtgtttccg attgatgaaa aaggcgggct ttatttatcg ccctttatct cagtcaatgc
    17341 cacttcagac attctgattc tcaacatccc atattacata tttaagaaaa tgatgtctta
    17401 tcatccgcag ctgcaaatga actttttggc tatgcttcag caaaatgttt tttgttccta
    17461 tcaattattt ttgcggtatc tgcatacatc acaggatgaa aacgccgagc ccggttctta
    17521 aatagagccg gtttttttga tctttgaaag gcggctaatg acccaagcgt tctgcctgaa
    17581 cgcagccttc cttctccttt gtgtgaacat tttgtgaaaa aagcggagtg tgtgacatag
    17641 ttcacaagga aacacgctgt ctctgtttat agtgaactta gcatcacctg actcggaagg
    17701 agtgaactct catgaagaaa aagaaaagga gtccgttgtt taggagattg aattatttct
    17761 ctcctatcga acaccattca aataaacata gccaaaccac ccgcgacgat cgcgattggg
    17821 agaatgtata cagaaacaga tggcagtacg acaaagtcgt tcgctccacc cacggcgtta
    17881 actgtacagg gtcttgcagc tggaatattt atgtgaaaaa cggaattgtc acgtgggaag
    17941 ggcaaaattt gaattatcca tcaacaggcc cggatatgcc tgattttgaa ccgagaggct
    18001 gcccgcgggg ggccagtttt tcatggtata tctacagccc gctgcgtgtg aaatatccat
    18061 acgtgcgcgg tgtactgatt aatttatggc gggaggcact gcaagaacat caaaatccat
    18121 tggaagcctg gaaatcgatc gtcgaaaacc ctgaaaaagc gaagtcctat aaacaggcga
    18181 gagggaaagg cggttttgtg cgcgctgaat ggccggaggt gctgaagctg atttcagcct
    18241 ctctgctgta tacagtgatg aaatacgggc ctgacagaaa cgtcggtttt tctccgattc
    18301 cggccatgtc catgatcagc catgcatcag gctcccggtt tatgtcgtta atcggaggcc
    18361 ctatgctcag tttttatgac tggtatgcgg atcttcctcc ggcatccccg caaatttggg
    18421 gtgaccagac ggacgttccg gaaagcagtg attggtacaa ttccggctat atcatcacat
    18481 ggggctccaa cgttccgtta acgagaacgc ctgacgcgca ttttttggcg gaggcccgct
    18541 ataaaggcgc taaggtcatt tcgatcagtc cggattttgc ggaatcctca aagttcgcgg
    18601 atgactggct gagtattcgc caagggactg acggggcgct tgcgatggcg atgggtcacg
    18661 tcattctgca ggaattttac gtgaaccaag aaactgaacg ttttattgag tacgcgaagc
    18721 aatacactga ttttccattt ctcgtcaccc tgtcaaaaga aaatggcgta tacacagcgg
    18781 gacggtttct gcatgcgaag gacatcgggc ggaagacaaa gcatgatcag tggaagcctg
    18841 cggtttggga tgaacagaca agttcatttg ccatacccca agggacaatg ggctcgcgct
    18901 gggacgggca gcagaaatgg aacctgcaca tgattgatga agaaaccggg gaaccgattg
    18961 aaccccgtct ctctgtgctc ggaatagagg atgaaatcgg cacggtgcgc attccttatt
    19021 tttcaaatga cggaaacaaa gtgctcgagc gggatcttcc tattaaaaaa atgaacctga
    19081 acggtgaaga gacgtacgtc acgaccgtgt ttgacttgat actggctaac tacggcgtaa
    19141 atcggggcat cggcgaacaa caagctgtct cctatgatga tcctgagccg tttacgcctg
    19201 cctggcagga acaaatgaca ggaatcaaaa aagaagctgt cgttaagatt gccagagagt
    19261 ttgctcaaaa tgcgatcgat acagacggcc ggtctatgat tatcgtagga gccggcatta
    19321 accactggtt caactccgac acgatctacc gagcagtgtt aaatcttgtt ttgcttgtag
    19381 gcgcccaagg cgtaaatggc ggaggctggg cccattacgt cgggcaggaa aagctccgac
    19441 ctgctgaagg atggcagacg attgcaactg caaaggactg ggagggcgtg cccaagctgc
    19501 aaaacggcac ttcatttttc tactttgcga cagatcagtg gcgttatgag gaccagccga
    19561 tcagtgattt ggcatcaccg attgctgcgt catcccgcta caagcaccac gctgattaca
    19621 atgtgctggc ggcgcggcta gggtggcttc cgtcttaccc gactttcaat caaaatggca
    19681 tcgatctgta taaagaagct gaaaaagcag gggcagcaac acctgaagac gtaggtgcgt
    19741 acgtggcctc acagctccaa gagaaaaaac tgaaattcgc gattgaagat cctgacaatg
    19801 aagtgaattt cccaaggaat ctctttgtat ggcgggcaaa tctgatctca agctcaggaa
    19861 aagggcatga atattttctc aagcatttgc tggggacaac gaacggttta atgaatgacg
    19921 acagcgacag catccgccct gaagaaatca aatggcggga gcaggcgccg gaaggaaagc
    19981 tcgacttatt aatcaatctt gattttcgaa tggcgggtac ggcgctgtat tccgatatcg
    20041 tgctgccggc ggcgacatgg tatgaaaaac acgatctcag cagcacagat atgcatccgt
    20101 tcattcatcc atttgctccg gcgatctcag ctccgtggga atcgaagtca gactgggata
    20161 ttttcaaggc gctgtcaaaa gccgtttccg atctggcaga agaagtcaat atggagccgg
    20221 tgaaagaagt ggttgcgacg ccgctcctcc acgacaccat gcaggaattg gcccagccat
    20281 tcggcaaaat caatgactgg agcaagggcg aatgtgaagc cattccggga aaaacgatgc
    20341 cgaacatcca agtcgttgaa cgggattaca aacacatttt tcataaaatg accgcactcg
    20401 gtcctaacgc tgctttaaag ccgagcggaa caaaagggat gagctggtca atagccgatg
    20461 aatatgaatc actcaaaaag agactgggag aaatcacctc agacagcgtg gcaaagggat
    20521 gtccaaatat aagtgaagca aagcaggcgg cagaagcggt tttaacccta tcatccactt
    20581 cgaatggaaa ggtcgccgta aaagcatggg aatcacttga aaacatcaca aacctgaagc
    20641 tgaaagacct ggcggaagag cgcgaggaag aatgctttac gttcgaacaa attacagccc
    20701 agccgaaaac ggttatcacg tctccggcat ttaccggctc tgaaaaagga ggccgcaggt
    20761 attcgccgtt tacgacgaat gttgaaaaat taatcccgtg gcggacactg acaggcagac
    20821 aatcctatta tgtcgatcat gaactgatga tggaattcgg tgaaacgatg gcgacattta
    20881 aaccgatcct ccagcaccgc ccgtttctaa gcaagcggcc tgatcaagag ggaaaagaaa
    20941 tcgtccttaa ttatttgacg ccgcataaca aatggtccgt ccacagcatg tattttgatt
    21001 ccctgccgat gctgacgctg ttccgcggcg ggccgaccgt atggatgaat aaagatgatg
    21061 cagaggatac ggatatcaaa gacaacgatt ggattgaatg cttcaaccga aatggcgtag
    21121 tcgtcgcgag agccgttttg tctcatcgga ttcctaaagg aatggcgttt atgcaccatg
    21181 cccaggaccg ccacatcaac gtgcccggca cgaaactgac aaataaccgc ggaggcaccc
    21241 ataacagccc gacaaggatt cacgtcaagc cgacacagat gatcgggggc tacgcccagc
    21301 tcagctacgg ctttaactat tacggcccaa cggggaatca gcgcgacctg aatgtcgtca
    21361 tccgcaagct gaaggaggtc gattggcttg aagattaaag cgcaaatcgg tatggtcatg
    21421 aacttggata aatgcatcgg ctgccacacg tgcagcgtca cctgtaaaaa cacatggaca
    21481 aaccgtaccg gtgcggaata tatgtacttc aataatgtag aaacaaagcc gggcatcggc
    21541 tacccgaagc aatgggagga ccaggacaaa tataaaggcg gctggacatt gaaaaaagga
    21601 aagctcgagc tg
//
