LOCUS       NZ_JAPWIK010000003     30097 bp    DNA     linear   CON 14-FEB-2024
DEFINITION  Rhodococcus qingshengii strain IEGM 766
            NODE_3_length_653427_cov_321.115482, whole genome shotgun sequence.
ACCESSION   NZ_JAPWIK010000003
VERSION     NZ_JAPWIK010000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Rhodococcus qingshengii
  ORGANISM  Rhodococcus qingshengii
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Nocardiaceae; Rhodococcus; Rhodococcus erythropolis group.
REFERENCE   1  (bases 1 to 653427)
  AUTHORS   Krivoruchko,A.V. and Elkin,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-DEC-2022) Lam, Institute of Ecology and Genetics of
            Microorganisms, Ural Branch of the Russian Academy of Sciences,
            Golev Str., 13, Perm, Perm Kray 614081, Russia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2022
            Assembly Method                   :: SPAdes v. 3.15.4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 311x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/14/2024 02:58:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,449
            CDSs (total)                      :: 6,385
            Genes (coding)                    :: 6,320
            CDSs (with protein)               :: 6,320
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 5 (23S)
            tRNAs                             :: 54
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 17 of 65
            Pseudo Genes (incomplete)         :: 52 of 65
            Pseudo Genes (internal stop)      :: 6 of 65
            Pseudo Genes (multiple problems)  :: 9 of 65
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:17:55
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 195771
            Orig. end                         :: 225868
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAPWIK010000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..30097
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="2"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..30097
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..30097
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:20097]"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..20097
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            complement(331..1311)
                     /locus_tag="O4271_RS12650"
                     /old_locus_tag="O4271_12645"
     CDS             complement(331..1311)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007735876.1"
                     /locus_tag="O4271_RS12650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O4271_12645"
                     /product="proline dehydrogenase family protein"
                     /protein_id="WP_269611565.1"
                     /transl_table=11
                     /translation="MNTDLQAQAADVLRRLALDESLKERTMADAATAALARKVAARYIG
                     GETIDDAFDRLPSIFARGHKASIEYTGESVRDPELANAETDVFVELAERIGTSGVDSTV
                     SFDLSHIGLVIDPEQCFRNVVRLAETTERAGAELIISAEASDRTDLVLDMHARLAERFT
                     HVGITVQARLHRTAKDLAALLDRPGRIRLVKGAFLEAESVAYPRGSAELRSAYLDYAAR
                     IVDSGHQVSIATHDRDILEALRAEHDSKLRGEYVEFEMLLGLGTEQLDALRGAGFTTRE
                     YVIFGTQWWLYVLNRIAEEPERVYTALIDAASTEPRMVVGSMEPR"
     gene            1473..1685
                     /locus_tag="O4271_RS12655"
                     /old_locus_tag="O4271_12650"
     CDS             1473..1685
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003943561.1"
                     /locus_tag="O4271_RS12655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O4271_12650"
                     /product="hypothetical protein"
                     /protein_id="WP_050656385.1"
                     /transl_table=11
                     /translation="MAAEARIVDTVSVEDSRASDPRVASKTEQKDAPKAGAVDLTSADT
                     VGLTSVKPAQRSVPRWAYSEVPLSR"
     gene            1652..1831
                     /locus_tag="O4271_RS12660"
                     /old_locus_tag="O4271_12655"
     CDS             1652..1831
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019746296.1"
                     /locus_tag="O4271_RS12660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O4271_12655"
                     /product="hypothetical protein"
                     /protein_id="WP_050656386.1"
                     /transl_table=11
                     /translation="MGLLRGAAVAVAAGGTAEQVAKAEAILAEARRALFEMLAEKPADA
                     QQAHAESTATLPAE"
     gene            complement(1841..2656)
                     /locus_tag="O4271_RS12665"
                     /old_locus_tag="O4271_12660"
     CDS             complement(1841..2656)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /GO_process="GO:0055072 - obsolete iron ion homeostasis
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1200: vibriobactin
                     utilization protein ViuB"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003943529.1"
                     /locus_tag="O4271_RS12665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O4271_12660"
                     /product="siderophore-interacting protein"
                     /protein_id="WP_007735878.1"
                     /transl_table=11
                     /translation="MSFCEPARVVTVTSLTPHMRRISIEAEGDWHWPTGGQGDERIDLA
                     FPKPGETEAEYDYFNNPDYGKADLGTEPPWRHYTVRKVHDGGRRLDIDFVVHPGGIAAD
                     WALRAEPGHLLGVFWSDSSRSHYQAPAGPRWQLLVADATGLPGLGRIVEELREGDVAQA
                     IIEVETEEDRQEFVTRGDVTYTWLVGSGLGKAPSALFEAVEKVEFPESESADIYAWVAC
                     ESATSRRIRKHLREVRGIARDKHNVVGYWREGADGHVSGMNSEEVTVGA"
     misc_feature    complement(2614..2629)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     gene            complement(2801..4039)
                     /locus_tag="O4271_RS12670"
                     /old_locus_tag="O4271_12665"
     CDS             complement(2801..4039)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019745836.1"
                     /locus_tag="O4271_RS12670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O4271_12665"
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="WP_064688028.1"
                     /transl_table=11
                     /translation="MDSRDAWQLDGEDLKGEVLDLVRVRHELQSRMVLLIVEMFSREVL
                     GGKGFRAIAQWLHGSTNLEIGECSLLVGLARLLMLEPVVGDAFHRGDVDALKARQVASF
                     CQHPPKNMTLADVDKARGILLGLASKNIADCDAVRAAIRRIEKQYGKREDGVPVGEDSE
                     RNEFYASKGLYGRVSVKGDLDAINGARLITLLSSLSAPTPEKDGVKDTRTPALRRADGF
                     CELLRRYERAGLGPIEGGVKPHITVTASAKDMTDLKALKDLLPSTQELGFAWADWVGPI
                     SIDTARMLACDCTVTRILLDENGVPLDCGKEARTATVPQRRALAVRDGGCAFPGCGTPS
                     GWCDAHHIVHWNDGGPTDLDNLILLCGHHHRTMHHTEWRVEIGPDRKTVFYPPMSIDPY
                     QQPIGGNSPPTAA"
     misc_feature    complement(4053..4068)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.95"
                     /tool="antismash"
     misc_feature    4054..4067
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.58"
                     /tool="antismash"
     gene            complement(4132..4749)
                     /locus_tag="O4271_RS12675"
                     /old_locus_tag="O4271_12670"
     CDS             complement(4132..4749)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015652325.1"
                     /locus_tag="O4271_RS12675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O4271_12670"
                     /product="response regulator transcription factor"
                     /protein_id="WP_003943536.1"
                     /transl_table=11
                     /translation="MIRLLLADDHAIVRAGLRALLESEADIEVVGEAGTAEEAIAFCAT
                     TPVDLVLMDLRFGPGKTGVDATRAVCALPNPPHVLVVTNYDTDADILSAVEAGASGYLL
                     KDTPPVELLSAVRAAASGDSVLSPAIASKLMTRVRKPETSLSPREIEVLKLVAAGRSNR
                     EIGKELFLSETTVKSHLVHIFGKLGVKSRTSAVARARELGSI"
     gene            complement(4746..5948)
                     /locus_tag="O4271_RS12680"
                     /old_locus_tag="O4271_12675"
     CDS             complement(4746..5948)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003943587.1"
                     /locus_tag="O4271_RS12680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O4271_12675"
                     /product="sensor histidine kinase"
                     /protein_id="WP_003943587.1"
                     /transl_table=11
                     /translation="MDEPGPNLAKLGEMHRSPLTPVFAGLQLGLHVLVMALAGVVFLRA
                     LIDESDLTATIIALAVIFVAVYLFGVAKRLRGNAARWWLAVLTLVWIATMAVSADAAYL
                     AFGLFFLYLHILRRPWSLLAVTAATAVAVVGTGLHRGWTIAGAVGPIIGAAVAVAIGLG
                     YQALYREAAERGRLIDELMNTREELASTSRDAGKFAERERLAAEIHDTVAQGLSSIQML
                     LHAAERADPDSPAIRQISLARETAADSLAETRQLIAELTPAALDGQSLADALRRICERA
                     SSPELEARSVVEGEAVRLPMPLEATLVRIAQGAVSNVLRHADATRMAVTLTYSDDTVSL
                     DVVDNGRGFDVAVLERGPAESFGLNAIRRRVELQGGTFSIESEPGHTAVAVTFPLEVGE
                     P"
     misc_feature    5947..5962
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 20.61"
                     /tool="antismash"
     gene            6063..7109
                     /locus_tag="O4271_RS12685"
                     /old_locus_tag="O4271_12680"
     CDS             6063..7109
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012691027.1"
                     /locus_tag="O4271_RS12685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O4271_12680"
                     /product="ABC transporter permease"
                     /protein_id="WP_039973533.1"
                     /transl_table=11
                     /translation="MFVAMRDLRAARGRFALISVVVLLVALLVSFLSGLTAGLRHQNVS
                     AIEAMNADTVVFADTGAGASFDESALTQDQVNAWTSTSKDVDPIGIGRGKAGLADGNQK
                     SVALFGADGGFGDVTPSASGTVVLSEGAARDLGAGAGDQVSVGTQQFTVSAVRGDDWYS
                     HSPVVWMTLDDWQAANPRGGVATVLAVTGASDASATDKAAATTSTTVSGSLDAIGSYKS
                     ENGSLTLMTLMLFAISALVIGAFFTVWTIQRTPDIATLKALGATTGSLVRDALGQALIV
                     LIAGVTVGIGLTAVAGSLIGDAMPFVLDASTTVVPAVALIGLGLLGAAFALRFLSTTDP
                     LTALGSAR"
     gene            7106..7846
                     /locus_tag="O4271_RS12690"
                     /old_locus_tag="O4271_12685"
     CDS             7106..7846
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003943539.1"
                     /locus_tag="O4271_RS12690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O4271_12685"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_003943539.1"
                     /transl_table=11
                     /translation="MTMTTGTTVLDIQNVDLTFPDGQSRVTALDDVSLRLHRGEIAAIT
                     GPSGSGKSSLLAVASTLIRPDSGHVYLRTPEGSTDIAALSRRAASELRRSSIGIVFQQS
                     NLVSSLTALEQLEVMAHLGQSVFTSRARRKAVKSKAMDLLDAVGLADQSGKRPSQLSGG
                     QRQRVNLARALMNDPQLLVVDEPTSALDQERGAAVMDLIIGVVREREAATLLVTHDRSH
                     LSRMDTVYRVVDGSLAEDQEALAA"
     gene            7958..8398
                     /locus_tag="O4271_RS12695"
                     /old_locus_tag="O4271_12690"
     CDS             7958..8398
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003943598.1"
                     /locus_tag="O4271_RS12695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O4271_12690"
                     /product="PAS domain-containing protein"
                     /protein_id="WP_003943598.1"
                     /transl_table=11
                     /translation="MERRRNVAQPPQSPIADLEQMPALILLDRLPVPVMAVHRDGSIVF
                     ANPSFADMLGYPKKAVSALRLQDILYDKDADDVSAEQAHRELSSEPGSVKEFVHSDSTL
                     VRATVSQSLLRRDDDTITLAVLHDLTERLWNNPRHIDDKPTK"
     gene            complement(8405..9031)
                     /locus_tag="O4271_RS12700"
                     /old_locus_tag="O4271_12695"
     CDS             complement(8405..9031)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003943606.1"
                     /locus_tag="O4271_RS12700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O4271_12695"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_003943606.1"
                     /transl_table=11
                     /translation="MTEVLREDTSARRKIIEAAREVFVDPGYAAATIKQLAAAAGVSVQ
                     SVYFVFGNKPSVLSALLDVAVAGDEEKTATLDRPWVAAALGAPHPLGQLRIQVHHGRLI
                     LERTADILLALRAAASADEDAARLWQINRTQRRTVQEHLMVGIVEKAPTVDLETAVNVA
                     LTLLSPETYTDLVVGAGWTGQQYEEWVVNTLAATLGLDRTVKSRK"
     gene            9083..10054
                     /locus_tag="O4271_RS12705"
                     /old_locus_tag="O4271_12700"
     CDS             9083..10054
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019746304.1"
                     /locus_tag="O4271_RS12705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O4271_12700"
                     /product="sugar nucleotide-binding protein"
                     /protein_id="WP_193604658.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 5.9e-06, bitscore:
                     20.8, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKVLVLGGYGAVGIPLMKQLAKVPEISAYSAGRDPARADVVVDL
                     KEPGAYSTVVRDFDVVVNASGFEDVRLADEAVRGGAAFVDVTATSNYCEELEAVDGPVL
                     MGVGLAPGLTSVLATEAHRLGDGPVDIVIGLGGGELHGPAATAWTYGMLGTRFPDPDGR
                     SVRNYTGMKTFRIPADAIGYRTGPAVRADFSDQHALTRDLGVPVRTYLRLDTSTATLGL
                     AAMTWAPALQKVVPKKLWGSDRWVAMARADTGPALWVSGRSQSVATAAIAARAVRVIRD
                     AAISKPTWFHAVETTESLQAAVPELSVRQWDGASRSSGKTVH"
     gene            complement(10001..11293)
                     /locus_tag="O4271_RS12710"
                     /old_locus_tag="O4271_12705"
     CDS             complement(10001..11293)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003943528.1"
                     /locus_tag="O4271_RS12710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O4271_12705"
                     /product="YcaO-like family protein"
                     /protein_id="WP_269611577.1"
                     /sec_met_domain="YcaO (E-value: 4.1e-49, bitscore: 163.2,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSSLVDRQTGIIRELVDAVVPQHFPPEFKLIHSYVSDSARFTPW
                     SSDSAGAGYCFDLGDRARPTAAAIGEAVERYCGNIVAKPIVRGSAEALIGASIELPQLA
                     RFDAAQYARPQFPFVEPTDDLEMDWTRGADLITGSDIWVPAELVWGSYPHFVARTGPAI
                     SPVAQAGLAAGPSVKFAIDNALREIAERDAMTLSWNGRRGVRIVTGIPEVLRRLGNHGT
                     LSTRWLSFDSDFGIPVLGALVHDGLTGYSTIGTACHEEAQTAAFKSLGEALQLQLLSAD
                     YDNPESGIGRAAASPTSPLAPWRADRSYAGAYRSDFADVMDYGCHLQLHLDPEIQARFE
                     SELVGAVVGEVGLDSLTSAAGTESALTAAGFRPAWVDLTTTDVLHAGLHVVRVVVPGCL
                     TNAAAGLPFLGSPRLVDSLAGRSARTIPLPH"
     gene            complement(11290..12630)
                     /locus_tag="O4271_RS12715"
                     /old_locus_tag="O4271_12710"
     CDS             complement(11290..12630)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003943577.1"
                     /locus_tag="O4271_RS12715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O4271_12710"
                     /product="YcaO-like family protein"
                     /protein_id="WP_007735889.1"
                     /sec_met_domain="TIGR03604 (E-value: 8e-74, bitscore:
                     243.9, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 1.2e-65, bitscore: 217.6,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDDLLVDARSGVLTSLEPHIRSDMPTGWVGWAARVADTRNFGGSG
                     SLFRADPYGFGASIRDDAAARGAATGEAVERYCGNVVPEDLVRSSASALELAGSRVVDP
                     AEFALYSEDQYRLPGFPFVPFTSDLNIRWALGHTMDEKVPTYVPAALTYLGYYTGTRRC
                     EPPIASLQYAGIAAGRSRDEAEMSALLELLERDATALWWCGDRSQPAIELSDWERLPTH
                     RQLGDLESQTRSVRVLLLPSPFGIPVAAAWIRDDRRGLVALGTACRPTVEAAVSKALVE
                     AYAVLAITIDLADPDGPTWRSVADGTLPAHLYKPFRADRRYRDEFDPQWKDVVDLPTVA
                     QLYLDPTMALAAEEHLFDYTETLSVSEIPVEAPVDLASLVALLTSRGHQPISVDLTTGD
                     ISIAGLHVVRVLTPGLYNNAPAAFPLLGGSRLTSASTTHLHLPVPLA"
     gene            complement(12623..14053)
                     /locus_tag="O4271_RS12720"
                     /old_locus_tag="O4271_12715"
     CDS             complement(12623..14053)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007735890.1"
                     /locus_tag="O4271_RS12720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O4271_12715"
                     /product="CocE/NonD family hydrolase"
                     /protein_id="WP_269611579.1"
                     /transl_table=11
                     /translation="MISLGVKIPAADGSSLATDVLLPPDSSPRGLIVIRTPYGRGWHLA
                     EGIEWRSRGIAFISQDVRGRHDSTGSWEPYVHEREDSAALAEWLQDQPWTPECVIASGA
                     SYAAGTAWAFATETNSADRSFRVDGVVSKVPTIGSDRVKRDPSAILLLAEHLAWWGEHG
                     DSSSSREGFIPALMRSDSSLLEHLPVQSMIEEVGLTSDSPGWLTPILRARKREDFGGDD
                     LVSADELSELDIAGLHIGGWDDAMIRETLRHFTSVGRGPQSLIVGPWAHDLRPGRVGET
                     SFGRLQVEWMESVFAARPLTINRVFDRGVGEWSTEPFVTGANRVHLEPDRKDAAYSFLY
                     DASRDRNNCVVLTFDIKHDSVLSGTPSVELKVHSPEGEADWIAELSVVDPAGVTRSIAR
                     GAGVSLQPTMVTIDLDPVLHTVRAGDVLSLRIAGSDFPRLARNLGDGDRYRGTRSTALH
                     QSFSGSLTLPILGGTDGG"
     gene            complement(14050..14862)
                     /locus_tag="O4271_RS12725"
                     /old_locus_tag="O4271_12720"
     CDS             complement(14050..14862)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003943559.1"
                     /locus_tag="O4271_RS12725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O4271_12720"
                     /product="hypothetical protein"
                     /protein_id="WP_007735892.1"
                     /transl_table=11
                     /translation="MYALADGHQLYPTPDGVWHYLTPDENAVTIGAPAEDLAELDNFLR
                     RSGSVLGPGAIEIADALVSRGVLAVPGQVPEIPRPQRVLMDGIGPVADACIALLSKALP
                     HLEVVSTTAPIEHDVASSDLVLSVAGAPPHDEWSELDTWCRRNQTPWQRVHAELGEICI
                     GPFFDGIGSASYRDVCGRRLAASRVPDHLQALWNHLAGSEPRPLELEPTAAAMASALAC
                     SDVVAGVHGAPPSHLHHQIRMNPRTLMMTRHPVLPLPGGVLEPAPTLR"
     gene            complement(14957..15145)
                     /locus_tag="O4271_RS12730"
                     /old_locus_tag="O4271_12725"
     CDS             complement(14957..15145)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007536315.1"
                     /locus_tag="O4271_RS12730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O4271_12725"
                     /product="streptamidine-related RiPP repeat protein"
                     /protein_id="WP_003943543.1"
                     /transl_table=11
                     /translation="MSNISFDSVSNSAPANALQGVGTNALVDNPFTFEPVAEATSAHAL
                     QGVGTNALVDNPFSFQS"
     misc_feature    15161..15176
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.99"
                     /tool="antismash"
     misc_feature    15163..15177
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.67"
                     /tool="antismash"
     gene            15238..16497
                     /locus_tag="O4271_RS12735"
                     /old_locus_tag="O4271_12730"
     CDS             15238..16497
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003943579.1"
                     /locus_tag="O4271_RS12735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O4271_12730"
                     /product="MFS transporter"
                     /protein_id="WP_007735895.1"
                     /transl_table=11
                     /translation="MSETPTTGSVEAQPHVFRDRSFRLFFTARTIAVAGAAVTGVAMPI
                     LVFDISRSPFLTSLAAAGTVLPYLVFGLFAGAVADRVNRRTVILCAQAVAALALASIPA
                     AQALGVLTAWHAVGVSICIGTCFVWFDAAAFGALPALVGGQRIPAANSALWTSSTLIDV
                     VFPAIAGVLVASIGPAYALGADALAYILAGLAMASIGASFSITPAAPKKSGTGIARDIR
                     EGLNFLWQSPLLRALTGVGFVNSLTQGAVTALLVVYASERLGISTSSPMIGAVWTAVSV
                     GGVVGAVLLPRLPAQWPVGAITVGALTIGPVVLFVVATTGNTGAAITALVVYSGCATVT
                     ILNGIGARQRLTPDRLQGRVNTTARMVAWGGSPVGALIAGAIAGRWDIGTAYLVACIFA
                     LVGALFAWASALRTDPYPHR"
     misc_feature    16511..16526
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.75"
                     /tool="antismash"
     misc_feature    complement(16513..16527)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 20.78"
                     /tool="antismash"
     gene            16582..17649
                     /locus_tag="O4271_RS12740"
                     /old_locus_tag="O4271_12735"
     CDS             16582..17649
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1011: transport
                     system permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007735896.1"
                     /locus_tag="O4271_RS12740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O4271_12735"
                     /product="iron ABC transporter permease"
                     /protein_id="WP_042453275.1"
                     /transl_table=11
                     /translation="MTLTSEAAPRVPSRPHPVGERGYVPFLLATAVVLVAVSTVAVWSG
                     AASVSFADVFAVLYAHVGGPPVDPLLDRIVWGLRVPRILIAALAGAGLSLAGAVLQALV
                     RNPIADPYILGVGSGASFGAVLIMTTGIGTGLSIGVPVAAFLGAMISLIAVLVLGRREG
                     MLVPLRMVLAGVAIGYLLSAATSFVQLRADPSQLSGVLFWLLGSVSGASWSDLGVPAAV
                     ITVCAAILLTQSRQLNALAMGDESAQSVGVDVRRTRLLLLVIASLLTAVVVSVAGGIGF
                     VGLLVPHAVRLLVGSDHGKLLPATALVGATFLVIVDLAARMLDAPNELPLGIITAGLGA
                     PFFLWLLRRDGGAQS"
     gene            17646..18440
                     /locus_tag="O4271_RS12745"
                     /old_locus_tag="O4271_12740"
     CDS             17646..18440
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019746313.1"
                     /locus_tag="O4271_RS12745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O4271_12740"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_054825351.1"
                     /transl_table=11
                     /translation="MRLSASGIHVVRGGRLVVSGVDLEAPEGSVVGLVGPNGSGKSSLL
                     RALYRSMKPRSGIVKVDEVNVWDDLSPRSAARIIGVVGQEHSSDFSFSVREVVATGRTP
                     HHSAFSRLGEIDRDIVSAALVRTGMQGFGSRLFAELSGGEKQRVMLARAIAQQPSVLVL
                     DEPTNHLDIRAQLELMELVAELGTTTIVAIHELALAAAYCDYVCLLSGGVVVATGPTAE
                     VLTEDLLSEVFGVQVHLGTHPLTGRPLLSFAPPLLPTKEAVS"
     gene            18437..19417
                     /locus_tag="O4271_RS12750"
                     /old_locus_tag="O4271_12745"
     CDS             18437..19417
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033: iron
                     compound ABC transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007735904.1"
                     /locus_tag="O4271_RS12750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O4271_12745"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_054831571.1"
                     /transl_table=11
                     /translation="MKTSIRTAALFCSAVATTAVLTACGNSTADSAAASSEKITVTNCD
                     RDITLPKTAERIVSLYPSMTELLIQLGAADRIVGQSNTDLSPPSPELADQFAAVPVLST
                     GVPAKEALLDARPDLIVSDGEYWFDGDRLQTMDELRDLGIPIFVNSGYCHKAVTEGRID
                     DVWSDIDGLGTLTGTREEAATLLADGKKSLAATEASVAGKEPVPTVMVQVSEGQSYALA
                     RGLYSSVLEAAGGSNLFENDLPDGKYFGQVATESVLAKSPKAVLVVYSTESARESTLDA
                     ARTAFAGTPAATSNAIFAVPEAWFAGELVSIDGAGEVSRLLHPGS"
     gene            19414..20097
                     /locus_tag="O4271_RS12755"
                     /old_locus_tag="O4271_12750"
     CDS             19414..20097
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007735907.1"
                     /locus_tag="O4271_RS12755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O4271_12750"
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_269611588.1"
                     /sec_met_domain="PF00881 (E-value: 2.1e-18, bitscore: 62.2,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTALERIEAVVSLHAALDRTVSPSELPFDEHALPPVTCESVELPA
                     ATPLPVCGFADVLQARRSRYDPAQTALRAGELSNVLHHSLVSSPTAGGMRELTLSFVLS
                     RPGDELGAGVYRYARGRAEAVRPGDVREHLRASLLQPEFVDVFPVLLFVVADVEAPLEK
                     YAMRHYRTMHVDAGVLVQNLYLVTEAMGLVGCAIAGFTDARVASLLNLATTQLPVMAFA
                     LGRRS"
     gene            complement(20099..20383)
                     /locus_tag="O4271_RS12760"
                     /old_locus_tag="O4271_12755"
     CDS             complement(20099..20383)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007735909.1"
                     /locus_tag="O4271_RS12760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O4271_12755"
                     /product="SHOCT domain-containing protein"
                     /protein_id="WP_007735909.1"
                     /transl_table=11
                     /translation="MSFLRRAGRVAVASSIHGNVQRRQRTRWAAEDQARAAQAQPVPPI
                     PDLPPLPPQAAPAASMDLKLEQLTKLGELKNAGVLTEAEFETQKARILA"
     gene            complement(20380..20832)
                     /locus_tag="O4271_RS12765"
                     /old_locus_tag="O4271_12760"
     CDS             complement(20380..20832)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003943563.1"
                     /locus_tag="O4271_RS12765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O4271_12760"
                     /product="DUF6325 family protein"
                     /protein_id="WP_218748673.1"
                     /transl_table=11
                     /translation="MSNQDQFGPIEYVAVEFPGGAPTSAGFEQLLILVDSGVIRILDLE
                     FVTKAADGSVAVVPASTFELADFDLAQFDGAASGLLDAGDIAAVGDELATGSVAAVLVY
                     EELAILPVIDAWTRSGAKIVTEGHLSLDELATALDNTAPGNTEKDA"
     gene            complement(20836..22482)
                     /locus_tag="O4271_RS12770"
                     /old_locus_tag="O4271_12765"
     CDS             complement(20836..22482)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003943582.1"
                     /locus_tag="O4271_RS12770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O4271_12765"
                     /product="MFS transporter"
                     /protein_id="WP_003943582.1"
                     /transl_table=11
                     /translation="MSVKPGAAATTAAVSTASWLPLIVVVLTQIQASFAVNALTVSMAG
                     ITTDLDTPATSVGTAITAGTFAMAAFILLGAKIGARYGTRLVFQIAVAIHGLAMAAVAL
                     SQSPAMLFVAQAASGAVIALIAPALTVFIATNFSGDQQAKAIGYLAAAIPAAGVLALLI
                     AGSFATTIGWRYSFALVVALAVVNLILSFRVKPVPPQKDITIDWAGAAIAAVAVILLSF
                     GFSGLNSWGVILATDAAPFSVIGVSPAAILIVLGTICAQGFFQWTRSRKAQNKPQLFNL
                     DVLKTGAERATTICMATMMFVGTAANFLIPLYMQIIQGRSSLQTSFSIIPYTLSIFIAS
                     TVVARLYKTYSPRLIARAGFVVVAAGLILLAFTIRGDWHQIFVVIGLITLGLGQGAIVA
                     LVFNTLLTAAPKELAGDVGAWRGLVHNMSGSVGIAVASVFAVGILGSLVSSQLIDNPTI
                     PASLKVESGINLDQVNFVPNDQLVVTLENTSATQAQIDEAIRINTEARLRALRTSLLVL
                     AGLSLLAIIPAGRMPNEVPALEEPQPTKGKK"
     gene            complement(22551..23798)
                     /locus_tag="O4271_RS12775"
                     /old_locus_tag="O4271_12770"
     CDS             complement(22551..23798)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007735921.1"
                     /locus_tag="O4271_RS12775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O4271_12770"
                     /product="hypothetical protein"
                     /protein_id="WP_269611596.1"
                     /transl_table=11
                     /translation="MEQTLTAVEDLTEVASRAVAAERDARSVRWHNPAAVRKAAAAVRD
                     SLDDERSALSRPSYSGLSPSPHMARQLELITTLEPPLPADAGIGTAAQAEADAVAAVTT
                     ARIALRAAHLAVLEARVAALDAGDTDTVAAAIRGYVPLNSGNPVVRHVQDLGSRIREEA
                     RHVVSGKPRSIAFRLGLSLGLGLAYLAFIRLFQWDAKEDRLPYLALYALSGVVGSVVCT
                     NALSFDAGRVRAALSGGTRLWHVLVAKNAVMLLLVGSAGFLLSAVLAWRSGSSADLVKA
                     CGQVLTMILLWLGVANVMSVSLPLRAEPMTARRHDGTWKQFLLSFVISYGVGLIVNLML
                     YWRVWAKTTLLEQMGGPWIPVLLLLASAAATWLLLTVLAVLLAEQPRFRRALHREMVVY
                     REETNHLQATIQHNSG"
     gene            23817..24404
                     /locus_tag="O4271_RS12780"
                     /old_locus_tag="O4271_12775"
     CDS             23817..24404
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019746321.1"
                     /locus_tag="O4271_RS12780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O4271_12775"
                     /product="DinB family protein"
                     /protein_id="WP_007735923.1"
                     /transl_table=11
                     /translation="MTTNSEKEDLQRYLQAARDALVWKLDGLSEYDIRRPMTRTGTNLL
                     GLVKHMIGVELGYFGPTFGRRVPDLPAWLRSEELNVDMWARADESTADIVETYRRTWAF
                     ADATIEEHDLDAPGFVKHWPEDRRDVTLHQILVHVVTETHRHAGHADIVRELIDGAAGM
                     KAGDNNLAPGDEAWWAEYTDRLETAAREAHHA"
     gene            complement(24406..25968)
                     /locus_tag="O4271_RS12785"
                     /old_locus_tag="O4271_12780"
     CDS             complement(24406..25968)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007735924.1"
                     /locus_tag="O4271_RS12785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O4271_12780"
                     /product="TRAP transporter large permease subunit"
                     /protein_id="WP_007735924.1"
                     /transl_table=11
                     /translation="MSTETDTGSAQTPAKKKFEFPGAVTMLAIVTILVWVAALFIPAGR
                     FGVDVDGSPVPGSFETVTSPLSFWERIQQLILSPVNGLYGVQDSITGFVDTDNIGRLFG
                     SVGVVLFIMALGAFISVSFATRSLETAVSQLATKLSDKGWLLITVIMVLFSLLGSTMGF
                     SVETFGFYALLIPLMTALGYDRMVAATMIILGALVGNMASTVNPFSIGVASGEAGVSIG
                     DGIVLRVILWIVLTAVAVVFVLRYAAKVKKDPSKSLVGFDIADDEDEEPAEPVDIDGKL
                     TGTQKLVLLITGLTFGLMIFSVIPWSSIFGATTGPAEYDAYHVTATEPYWFELNWWFPQ
                     LAMLFILAAVLVGIVAKMGEKKIVSLITRGAGDMVGPAIVILLARGVSVIMTNTETLDT
                     ILNAMEQLVSGASAGVFAILVMLVNIPLAFLIPSSSGHATLAMPLLAPLGDFAGVSRAL
                     VITAFQMGHGLMLMVAPTNVVVVGGLAMAKVGYDKFLRFVWPLLLINFVIVVVVIGAAA
                     VFE"
     gene            complement(25965..27341)
                     /locus_tag="O4271_RS12790"
                     /old_locus_tag="O4271_12785"
     CDS             complement(25965..27341)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1247: acetylornithine deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007735926.1"
                     /locus_tag="O4271_RS12790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O4271_12785"
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="WP_030535870.1"
                     /transl_table=11
                     /translation="MPEESASPSYSTIKETVAALMPALESELVELVRIPSIATEGFPSE
                     PLFEAHDLIVSLLEKSGVTKIEKLEITGKTAPVIIATVPGPEGAPTVLMYSHYDVVPAD
                     DVELWDSPPFEPSKRDGAIYGRGTADSKANVIGMIGALRVFDGKPPVTVKLVIEGQEEF
                     GSPFDNYPPEAPELFAADAMVIADVGSVRPGSPTLTVALRGSAQVIVELTTLGADKHNG
                     LYGGAAPDARLALIRALASLHDDNGDVAIDGLLREPWTGSSYTEDEFRTLAEIQDGLPL
                     LGTGGIGERIWSGPAITVTGIDAPPVDGAVNAVASTARAVINLRVHPRQPAIEAQAALV
                     RHLEALRPFGLQLTVTAGETGDGFAAAEGGPAFDAALSALSQSWGEPAGLMAGGGSIPL
                     VMALDTAVPTAEKLLFGATDGYANIHGPNERVLLDELEKAVVAKALFFQEYAHTFEGKK
                     "
     gene            27492..28127
                     /locus_tag="O4271_RS12795"
                     /old_locus_tag="O4271_12790"
     CDS             27492..28127
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007735928.1"
                     /locus_tag="O4271_RS12795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O4271_12790"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_019746323.1"
                     /transl_table=11
                     /translation="MTVTTSETQERARTARKLGDGPRRAGLLDTAALCFGELGYDAVTV
                     ETITTRADVSRATFYAYFSSKDEVFRAVAEMMCRRFLDAQHMEGPAAEDLREVLRTTTS
                     AFITAVYTYGDLLAVIEHRARVDSEVERSWSAVREKLVSRYVRFVERIRQVHDVDPCVS
                     PPVLVQMISDAQMAGGARLSKASVEEQNQFIADMTTMSERLIGFEESK"
     misc_feature    complement(28129..28142)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.14"
                     /tool="antismash"
     gene            28153..29850
                     /locus_tag="O4271_RS12800"
                     /old_locus_tag="O4271_12795"
     CDS             28153..29850
                     /NRPS_PKS="Domain: AMP-binding (43-468). E-value: 7.4e-93.
                     Score: 303.3. Matches aSDomain:
                     nrpspksdomains_O4271_RS12800_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003944167.1"
                     /locus_tag="O4271_RS12800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O4271_12795"
                     /product="AMP-binding protein"
                     /protein_id="WP_116057475.1"
                     /sec_met_domain="AMP-binding (E-value: 4.2e-98, bitscore:
                     323.8, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEQDVLEAALAEISALQQAHWPAGIPRAVEYPLEGGGLVDYLRH
                     WAIERPDTPAIIFYGRVITYSEYDELSDRFAGWLLSLGVERGDRVGVHLVNCPQFHIAM
                     LGILKVGAVHVPINPLFREHELIHELNDAGVKVLLTQNTFSKLVKKVRSQTPLEHVAKT
                     AVSDMLTAIPTVELPFEVDDPRLSDWQSIITSERATPVATELDSLAALNYTGGTTGMPK
                     GCEHTQRHMVYTAATATLAGGDQVGANPPVSLVFLPIFWIAGEDFGILVPLVNGGTVVL
                     LNRWDAETTLDAVEAYGVTSLVGTVDNYVELMDTPGFAERNLSTLQNVMAVSFVLKLDP
                     ATRQRWREATGGVLREASYGMTETHTADTITLGFQDGDYDLKSEPVFCGIPVPGTDVLI
                     VDHDGRPVPVGEHGQIIVRSPSILSAYYRNEAATADAIRDGWLQTGDVGKFSERGGLHY
                     LARNKEMIKTNGMSVFPSEVEALLMLHPAIEKAAVVPKPDPDKGQVAFAFVQLVEGSDT
                     AADEIVSWAKENMATYKVPEVEVLEALPMTATGKVRKGDLFERTQGDK"
     aSDomain        28282..29556
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_O4271_RS12800_AMP-binding.1"
                     /evalue="7.40E-93"
                     /label="O4271_RS12800_AMP-binding.1"
                     /locus_tag="O4271_RS12800"
                     /protein_end="468"
                     /protein_start="43"
                     /score="303.3"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="RHWAIERPDTPAIIFYGRVITYSEYDELSDRFAGWLLSLGVERGD
                     RVGVHLVNCPQFHIAMLGILKVGAVHVPINPLFREHELIHELNDAGVKVLLTQNTFSKL
                     VKKVRSQTPLEHVAKTAVSDMLTAIPTVELPFEVDDPRLSDWQSIITSERATPVATELD
                     SLAALNYTGGTTGMPKGCEHTQRHMVYTAATATLAGGDQVGANPPVSLVFLPIFWIAGE
                     DFGILVPLVNGGTVVLLNRWDAETTLDAVEAYGVTSLVGTVDNYVELMDTPGFAERNLS
                     TLQNVMAVSFVLKLDPATRQRWREATGGVLREASYGMTETHTADTITLGFQDGDYDLKS
                     EPVFCGIPVPGTDVLIVDHDGRPVPVGEHGQIIVRSPSILSAYYRNEAATADAIRDGWL
                     QTGDVGKFSERGGLHYLARNKEMIKT"
     CDS_motif       28783..28830
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_O4271_RS12800_0001"
                     /evalue="2.10E-03"
                     /label="NRPS-A_a3"
                     /locus_tag="O4271_RS12800"
                     /protein_end="226"
                     /protein_start="210"
                     /score="11.2"
                     /tool="antismash"
                     /translation="LNYTGGTTGMPKGCEH"
ORIGIN
        1 tctacacgta tgggcccgac aacgttccgg agttgagcta ccgaggtgag gaaggacggt
       61 tcggcatgcg cttggctttt gtcggtgtcg gtccccaaat cgagctgatc gaactcctcg
      121 agggccccag ctcgtaccac gaatggcatt cgcgtcacgg tttcggattg caccatctgg
      181 gttttgtcgt cccgtcgatc aaggacgcga tgatcgaaat ggcggaacac gacctcgatt
      241 tgattcagtc ggggtacggc tatggggcga acggggacgg aggttttgcg tactacgaca
      301 ctcaggattc ggtcggcgcg attgtcgagc tcatcgaggt tccatcgatc cgacgaccat
      361 ccgaggttct gtagaagccg cgtcgatcag cgcggtgtag acacgctccg gctcttcggc
      421 gatgcgattg agtacgtaca gccaccactg tgttccgaag atgacgtatt cgcgtgtggt
      481 gaagcccgct cctcggagtg cgtccagttg ctcggtgccg aggccgagca gcatctcgaa
      541 ctcgacgtac tcgcctctga gcttcgaatc atgttcggcg cgtagtgctt cgaggatgtc
      601 gcggtcatgt gtcgcgatgg agacctggtg acccgagtcg acgattcggg ctgcgtagtc
      661 gagatacgcg ctgcgcagtt cggcactacc gcgtgggtag gcgacggact cggcttcgag
      721 gaaggcgccc ttcacgagac ggatgcggcc gggtcggtcc agcagagcgg cgagatcctt
      781 tgccgtgcgg tgcagtcggg cctgaacggt gatccccacg tgagtgaagc gctcggccag
      841 tcgcgcgtgc atgtcgagga ccaggtcggt gcggtcggac gcttcggcag agatgatcag
      901 ctcggcaccg gcgcgttccg tggtctcggc caggcgcacg acattgcgaa agcactgctc
      961 cggatcgatg accaagccga tgtgcgagag gtcgaacgac acggtgctgt cgacgcccga
     1021 cgttccgatc cgttccgcca attccacgaa cacatcggtt tcggcgttcg cgagttcggg
     1081 atcccggacg ctttccccgg tgtattcgat gctcgccttg tgtcctcgcg cgaagatcga
     1141 ggggagtcgg tcgaaagcgt cgtcgatggt ttcgccgccg atgtagcgag cggcgacttt
     1201 ccgtgcgagt gctgccgtcg cggcgtccgc catggtgcgt tctttcaggg attcgtcgag
     1261 tgcgaggcgg cgtaggacgt ccgcggcctg ggcttgtaga tccgtgttca cggcttcagc
     1321 gtatccggac gagggtgcgg gaattattct acgaactctt gcgttcgatc tattgtcgat
     1381 atatcgtcga tacgtcaaac aaacacagac agtccaggag gacaacatgt acgccccaca
     1441 caacaaccca gaaatgcaag aacgtcgcga gcatggccgc cgaggcccgc atcgtggaca
     1501 cggtttccgt cgaggattcg agggcgagcg acccgagggt cgcttcgaag accgagcaga
     1561 aggacgcccc gaaggccggc gcggtcgact tgaccagcgc ggacacggtc ggcctcactt
     1621 cggtgaagcc ggcgcagcgc tccgtcccgc gatgggccta ctccgaggtg ccgctgtcgc
     1681 ggtagccgca ggtgggaccg ccgagcaggt agccaaggcc gaggcaattc tcgccgaggc
     1741 acgccgagca ctgttcgaga tgctggcgga aaagccggct gacgcgcagc aggctcacgc
     1801 agaatctacc gccacgctgc cggcagagtg atcacggcgc tcaggcgccg acggtgactt
     1861 cctcgctgtt catgccggaa acgtggccgt cggcgccctc tcgccagtac ccgacaacat
     1921 tgtgcttgtc gcgagctatt cctcgaactt ccctcagatg cttacgaata cgacggctgg
     1981 ttgcgctttc gcacgccacc cacgcgtaga tgtcggccga ttcggattcg ggaaactcga
     2041 ccttctccac agcctcgaac agtgcgctcg gcgcctttcc gaggccactc cccacgagcc
     2101 acgtgtacgt gacgtcgccg cgagtgacaa attcctgtcg atcctcttcg gtttcgacct
     2161 cgatgatcgc ctgtgcgaca tcgccttcac gaagttcttc gacaatcctg cccagtccgg
     2221 ggagacccgt ggcgtctgcg accagcagct gccagcgagg acccgctggt gcttggtagt
     2281 gggaccgcga actgtccgac cagaagacgc ctagtaggtg acctggttcg gcccgcaggg
     2341 cccaatccgc tgcaataccg ccagggtgca cgacgaagtc gatgtccaga cgtcggccgc
     2401 cgtcgtgcac cttgcgcacg gtgtagtgcc gccacggtgg ctcggttccg agatcggcct
     2461 tgccgtagtc gggattgttg aagtagtcgt attctgcttc tgtttcaccg ggtttcggga
     2521 atgcgaggtc gatgcgctcg tcgccttgtc cgccggtcgg ccagtgccag tcgccttctg
     2581 cctcgatgct gattcgccgc atgtgcgggg tcagggacgt gacggtgaca acgcgggcgg
     2641 gttcgcagaa agacatgcct cgaccctatg ggtccggcgt gtcgaagtgg agacagatgc
     2701 tgtcgcaaga cggacatcga gcgcagccga aaaggccagc gtatgccccg gggcatgatt
     2761 cttccccggt gcacacgctg gccttttcag ttatgtcggt tcacgccgct gtcggtgggc
     2821 tgttcccacc gatcggctgt tgatacggat cgatcgacat cggtggatag aacactgttt
     2881 tccgatccgg cccgatctcc acccgccatt cggtgtggtg catcgtccgg tggtgatgac
     2941 cgcacaacaa gatcaggttg tcgagatctg ttgggccacc atcgttccag tgaacaatat
     3001 gatgggcatc gcaccacccc gatggtgtcc cgcatcccgg aaacgcacac ccaccatcac
     3061 gaaccgccaa cgcccgccgc tggggtaccg tcgcggtcct tgcttctttg ccgcagtcga
     3121 gcggaacacc gttctcgtcc aggaggatcc gggtgacggt gcagtcgcac gccagcatcc
     3181 gggcagtatc gatactgatc gggcccaccc aatccgccca cgcgaacccc agttcctgag
     3241 tcgacggcaa gaggtccttc aacgccttga ggtctgtcat gtctttcgcc gacgcggtaa
     3301 cggtgatgtg tggtttcact ccgccctcga tcggacccaa ccccgcccgc tcgtaccgcc
     3361 gcagtagttc gcaaaacccg tccgcgcgcc gtagcgccgg cgtgcgggtg tccttgacgc
     3421 cgtccttctc cggcgtcggc gccgacaggc tcgacagcaa cgtgatcaga cgggccccgt
     3481 tgatcgcatc caaatcaccc ttcaccgaca ctcgcccgta caagcctttc gaggcgtaga
     3541 actcgttacg ctccgaatcc tcaccaaccg gaacgccgtc ctcgcgtttt ccgtactgct
     3601 tctcgatccg ccggatcgcc gcccgcaccg catcacaatc cgcgatgttc ttcgacgcca
     3661 ggccaagcaa gatcccgcgg gccttgtcca catccgccag ggtcatgttc ttgggcggat
     3721 gctgacaaaa cgacgccacc tgacgggctt tcaacgcatc cacgtcaccg cgatgaaacg
     3781 catcgcccac aacgggttcg agcatcaaca accgcgccaa cccgaccagc agactgcact
     3841 caccgatctc cagattcgtc gaaccatgca accactgcgc gatcgcccga aaacccttcc
     3901 caccgagaac ctcccgggaa aacatctcca cgatcagcaa caccatccgc gactgcaact
     3961 cgtgccggac acgcaccaga tccagaacct cacccttgag gtcctcgcca tccagttgcc
     4021 acgcatcccg actgtccatg ctcaaagttt aatcgaacaa agtttcgaac acaagagaat
     4081 cgcaggcgaa aattgctgct gtccagctac tttcgacaat tcgggcaaat gtcagattga
     4141 acccaactcg cgcgcacgag ctaccgccga cgtccgcgac ttcactccca acttgccgaa
     4201 gatgtgaacc aggtgcgact tgaccgtggt ctcactcagg aacagttctt tgccgatctc
     4261 tcggttggag cgacccgccg ccaccaactt cagaacttcg atttcccttg gactgaggct
     4321 ggtttcgggc ttacgtaccc gagtcatgag cttcgacgcg atggcggggg agagaacgct
     4381 gtccccgctc gcagcggcgc ggacggctga cagcaactcg accggtggtg tgtccttgag
     4441 taggtacccg ctggccccgg cctcgacagc gctcaagata tctgcatccg tgtcgtagtt
     4501 ggtcacaacg agtacgtgcg gcggattcgg cagcgcgcac accgcgcggg tggcgtcgac
     4561 gcccgtcttc ccggggccga atcgcaggtc catgagcacg aggtcgaccg gcgtggtggc
     4621 gcagaaggct atggcttcct cggcggtgcc cgcttcgccg actacctcga tgtcggcttc
     4681 gctttcgagc agcgctcgta acccggcgcg cacgatcgcg tgatcgtcgg cgagcagcag
     4741 gcggatcacg gttcgccgac ttcgagagga aacgtcactg cgacggccgt gtgtcccggc
     4801 tcggactcga tggagaaagt cccgccctga agttcgacgc gtcggcgaat tgcattgagg
     4861 ccgaaagatt ccgccgggcc acgttcgaga actgccacgt cgaaaccgcg accgttgtcg
     4921 accacgtcga ggctgacggt gtcatcggaa taggtcagtg tcacagccat tctggttgca
     4981 tccgcatggc ggagaacatt ggacaccgcg ccctgagcga tgcgtaccaa tgttgcttcg
     5041 aggggcatcg gcagccgcac tgcctcgcct tcgaccacgg agcgcgcttc cagttcagga
     5101 ctgctcgcgc gttcgcagat tcgacgaagc gcgtcggcga gcgactgacc gtccaaggcc
     5161 gcgggcgtca attcggctat gagttggcgg gtttcggcaa gactgtccgc ggcagtttcc
     5221 cgtgcgaggc tgatctgacg gatggccggg ctgtccggat cggcgcgttc ggcagcgtga
     5281 aggagcatct ggatgctcga aagtccctgg gcgacggtgt cgtgaatctc ggcggcgagt
     5341 ctttcacgtt ccgcgaattt tccggcatcg cgagacgtcg acgccaattc ttcacgagta
     5401 ttcatcaact cgtcgatgag acgaccgcgc tcggccgcct cgcggtacag cgcttgatat
     5461 ccgaggccga ttgcaaccgc tacggcagcg ccgatgatcg ggccgacggc gccggcaatc
     5521 gtccatccac gatgcaggcc ggtgccgacc acggcgacag ccgttgccgc ggtgacggcg
     5581 agaagactcc aggggcgtcg cagaatatgg agatagagga agaagagtcc gaacgcgagg
     5641 taggcggcgt cggcggatac cgccatcgtc gcgatccaga cgagggtcag cacggccagc
     5701 caccagcggg cagcgttgcc gcgcagcctt ttggcgaccc cgaaaagata gacggcaaca
     5761 aagatcacgg ccaacgcgat gattgttgcg gtcaggtcgg attcgtcgat cagcgctcga
     5821 agaaacacca caccggccag cgccatgaca aggacatgca ggcccagttg taggccggcg
     5881 aagacaggcg tgagcggcga tcggtgcatc tcgcccagct tagcgaggtt cgggcctggt
     5941 tcatccatca aaagttgtaa accgggatgg ttctttcgag cgctggaatg tcgatccgag
     6001 gtgcgatgga aagagtctgc atccgcgaga gcgtagaggc aagcacagga aaggaattca
     6061 cagtgtttgt cgcaatgagg gacttacggg cagcgcgagg tcgtttcgcg ctgatctccg
     6121 tcgtggttct gttggttgca cttctggtca gttttctcag cgggttgact gcaggacttc
     6181 gccatcagaa cgtgtcggcc atcgaggcca tgaatgccga cacggtggtg ttcgccgaca
     6241 ccggagccgg ggcgtcgttc gacgagtcgg cgctcacgca ggaccaggtc aacgcttgga
     6301 cctccacgtc gaaggacgtc gatcccatcg gaatcggtcg cgggaaagcg ggattggccg
     6361 acggaaatca gaagtcggtg gccctgttcg gcgctgatgg cggtttcggt gacgtgacgc
     6421 cgtcggcgtc aggcactgtg gtgttgagcg aaggtgccgc ccgcgatctg ggggcgggcg
     6481 ccggcgatca ggtgagtgtc ggtacgcagc agttcaccgt cagcgccgtt cgcggtgacg
     6541 actggtacag ccattcgccc gtcgtctgga tgacgctcga cgactggcag gcggccaatc
     6601 cacgcggcgg agttgcgaca gtactggctg tcaccggagc ctccgacgct tccgcaacgg
     6661 acaaggcggc tgcgacgacg tcgacgacgg tcagcggttc gctcgacgcg atcggttcgt
     6721 acaagtcgga gaacgggtcg ttgacgttga tgacgctcat gttgttcgcg atctcagcct
     6781 tggtgatcgg tgcgttcttc acggtgtgga cgatccagcg aactccggac atcgcgacgc
     6841 tgaaagcgct cggtgcgact accggttcgc tggtgcgcga cgcactgggt caggcgctca
     6901 tcgttctgat tgccggtgtc accgtcggaa tcgggctgac ggccgtggcc ggatcgctga
     6961 tcggtgacgc catgccgttt gtcctggacg catccaccac cgtcgtacct gccgtggcat
     7021 tgatcgggct cggtctgctc ggcgcggcct ttgcacttcg attcctctcg accaccgatc
     7081 cactcacagc attggggagc gcacgatgac catgacaacc ggcaccacag ttctcgacat
     7141 ccagaacgtc gatctgacgt ttcccgatgg gcaatcgcgg gtgacggcgc tggacgacgt
     7201 gtctctgcga ctgcaccgcg gcgagatcgc cgcgatcacc gggccgtcgg gttcgggcaa
     7261 gtccagcctg ttggcggtgg cgtcgacgct gatccgtccg gattccgggc acgtctatct
     7321 ccggacgccg gaaggcagca ccgacatcgc tgcgctgagt cggcgggcgg cgtcggagct
     7381 gcgacgctcg tcgatcggca tcgtcttcca acagtcgaac ctcgtgtctt cgctgactgc
     7441 actggagcag ctcgaggtga tggcgcatct ggggcagtcc gtgttcacgt cacgggcccg
     7501 tcgcaaggcc gtgaaatcaa aagcgatgga tttgctggac gctgtcgggc tcgcggatca
     7561 gagcggaaaa cggccgtccc agctgtcggg cgggcagcga cagcgcgtca atctcgcgcg
     7621 agcattgatg aacgatccgc agcttctcgt ggtcgacgag cccacgagtg cgctcgatca
     7681 ggagcgcggt gccgctgtca tggatctgat catcggggtg gtgcgggaac gcgaggcggc
     7741 aacccttctc gtgacacacg accgaagtca cctgtctcgg atggatactg tctatcgtgt
     7801 tgttgacggt tccttggcgg aggatcagga ggcgctcgcg gcgtgactca ggcgggcacg
     7861 attcgggcat tcgtcactgc atccgggcgg gaagtcaacc cgcgatttgc tgggcagtta
     7921 gactgttgtc gactcgggca acttgagagg acgtgttatg gaacgccgcc gcaacgttgc
     7981 gcagccgcca caatcgccga tcgcggatct ggagcagatg cctgccctga ttctcctcga
     8041 caggcttccg gtgccggtca tggccgttca ccgcgacggc agcatcgttt ttgccaatcc
     8101 gtccttcgct gacatgctgg gatatcccaa gaaggccgtc tcggcgttgc gtttgcagga
     8161 catcctctac gacaaggatg ccgacgacgt cagtgcagag caggcccatc gtgaactgag
     8221 ttccgagccg ggctcggtca aggagttcgt gcactccgac tccacgttgg tgcgcgcgac
     8281 ggtcagccag tctctgctcc gacgggacga cgacacgatc acccttgccg tcctccacga
     8341 tttgacggag cgcctgtgga acaacccacg gcacatcgac gacaagccca ccaagtaatc
     8401 ccagctactt ccgggatttg acggttcggt ccaggccgag ggtggcggca agggtgttga
     8461 ccacccattc ttcgtactgt tggccggtcc aacccgcgcc gaccacgagg tctgtgtagg
     8521 tctcgggact gagcagcgtg agtgcgacgt tcacagctgt ttcgaggtcg acggttggcg
     8581 ctttttcgac gatgccgacc atcagatgtt cctgcaccgt gcgtctctga gtgcggttga
     8641 tttgccacag acgggcggcg tcctcgtcgg cggaagcggc ggcccgcagt gccagcagga
     8701 tgtctgcggt gcgttccaga atgagccgtc cgtggtgaac ctgaatccgg agttgtccga
     8761 gtggatgtgg ggcgccgagt gctgccgcca cccacggacg gtcgagagtt gccgtctttt
     8821 cctcgtcgcc cgcaacggcc acgtcgagta gtgctgacag cacgctcggc ttgttgccga
     8881 acacgaaata gacactctgc accgacacgc ccgccgccgc ggcaagctgc ttgatcgtgg
     8941 cggccgcgta gccgggatcg acaaaaacct cacgcgctgc ctcgatgatc ttgcgccgcg
     9001 ccgacgtgtc ttcccgaaga acctcagtca tgattagagt ctaactctag agtcgaactc
     9061 tagcgactcg ggaggcgaag taatgacgaa ggttcttgta ctcggtggct acggtgccgt
     9121 cgggattccc ctgatgaaac aactcgcgaa ggtccccgaa atctccgcgt actccgccgg
     9181 ccgtgaccct gcccgcgcgg acgtcgtcgt tgatcttaaa gaaccaggcg cgtattcgac
     9241 tgtggttcga gacttcgatg tcgtggtgaa tgcgtcgggt ttcgaggatg ttcgcctggc
     9301 cgacgaagcg gtacgcggtg gggcggcatt cgtcgacgtc acggcaacct cgaactactg
     9361 cgaagaactg gaagcggtcg acggacccgt cctgatgggc gtcggattgg caccgggatt
     9421 gaccagtgtc cttgcaaccg aggcgcatcg actcggcgac ggacccgtgg acatcgtgat
     9481 cggcctcggc ggcggagaac tacacggacc ggccgcaacg gcgtggacgt acgggatgtt
     9541 gggcacgagg tttcctgatc ccgacggacg atcggtccgc aactacaccg ggatgaagac
     9601 gtttcgaata ccggccgatg cgatcggcta ccgcaccggt cctgctgtgc gggccgactt
     9661 ttcggaccag catgcgttga cgcgagacct cggtgttccg gtcaggacgt acctgcgatt
     9721 ggacacgtcc accgcgacgc tcggacttgc ggccatgacg tgggcacccg cgctacagaa
     9781 ggtcgtgccg aagaagctgt ggggctcgga tcgttgggta gcgatggccc gagcggatac
     9841 cggcccggcg ctgtgggttt cggggcgtag ccagtcggtc gcgacggcag ctatcgccgc
     9901 gcgcgccgtg cgggtgattc gggatgccgc gatctcgaag ccgacgtggt tccacgcggt
     9961 ggaaaccacc gagtcgttgc aagcggcggt tcccgaactg tcagtgcggc aatgggatgg
    10021 tgcgagccga tcgtccggca agactgtcca ctagtcgggg cgagccgaga aacggcaatc
    10081 cggcggccgc attggtgaga caaccgggta cgacgacgcg gacgacgtgc aggccggcgt
    10141 ggagaacatc agttgtggtg agatcgaccc atgccggccg gaaaccggct gccgtcagag
    10201 cgctttcggt gccggcggct gatgtcagag agtcgagtcc cacctcgccg acgacggcac
    10261 cgaccagctc actctcgaat cgtgcttgga tctccgggtc caggtgaagt tgcaggtggc
    10321 atccgtagtc catcacgtcg gcaaaatccg atcggtaggc gcctgcatag cttcggtcag
    10381 ctcgccaagg cgcaagcgga ctggtcgggg aggccgcggc tcgaccgatg ccgctctccg
    10441 ggttgtcgta gtcggcggaa agcagctgca gctgaagcgc ttcgccgagt gacttgaacg
    10501 cagccgtctg ggcttcttcg tggcaggcgg taccgatggt cgagtatccg gtgagtccgt
    10561 cgtggacgag ggcgccgagc accgggatcc cgaaatcgct gtcgaatgac aaccacctgg
    10621 tcgagagggt gccgtgattc cccagtcgcc gaagcacctc gggaatgccg gtgacgatcc
    10681 gaacgccgcg tcttccgttc caggacaacg tcatcgcgtc tcgttcggct atctcgcgca
    10741 aggcattgtc gattgcgaac ttcaccgagg gtccggcggc gagacccgcc tgagccaccg
    10801 gagagatcgc cggacccgtc cgggcgacga aatgaggata cgaaccccag acgagttcgg
    10861 ccggtaccca gatatccgaa cccgtgatca ggtcggctcc gcgagtccag tccatctcca
    10921 gatcgtcggt tggttcgacg aacgggaact gtggccgcgc gtactgggca gcgtcgaaac
    10981 gcgcgagttg tggcagctcg atgcttgctc cgatcaacgc ttcggcggac ccgcggacga
    11041 tcggtttggc gacgatgttg ccgcaatacc gttccaccgc ttcgcctatc gcagctgcgg
    11101 taggccgcgc acggtcaccc agatcgaagc aatatccggc gcccgccgag tcgctggacc
    11161 agggtgtaaa gcgtgctgaa tcactgacat acgagtgaat cagcttgaac tcgggcggaa
    11221 agtgctgggg aacaacggcg tcgaccagct ctcgaatgat cccagtttgg cggtcgacga
    11281 gcgaagatgt catgcgaggg ggaccggcag atgcagatgg gtggtcgatg cgctggtcaa
    11341 tctgctacct ccaagaaggg gaaaggctgc cggggcattg ttgtacaggc ccggagtcag
    11401 gacgcggacg acgtgcaacc cggcaatcga gatgtcgccg gtggtgagat cgacggaaat
    11461 cggctggtgc ccccgtgagg tcagaagcgc tacgagagaa gccagatcca ccggcgcttc
    11521 gacgggaatc tctgataccg agagtgtttc ggtgtagtcg aagagatgtt cctccgcggc
    11581 cagggccatc gtgggatcaa gataaagttg ggcaacggtc ggcagatcga cgacgtcttt
    11641 ccattgcgga tcgaactcgt cccggtaacg acggtcggcc cgaaagggtt tgtacaggtg
    11701 cgccggcagc gttccgtccg ccacgctgcg ccaggtcggc ccgtcggggt cggcgaggtc
    11761 gatcgtgatg gcaagtaccg cgtacgcctc gaccagtgcc ttcgagactg ccgcctccac
    11821 cgtcggtcga caagctgtgc ccagcgcgac cagtccacgt cggtcatcgc ggatccacgc
    11881 tgcggcgacg ggaatgccga agggggaggg aagcagcagc actcgaacgc tccgggtctg
    11941 gctctccaga tccccgagtt ggcggtgcgt aggcaaccgc tcccagtcgg aaagctcgat
    12001 cgccggctgt gaccggtccc cgcaccacca cagcgcggtg gcatcgcgtt cgagaagttc
    12061 cagcagagct gacatctcgg cctcgtcgcg tgagcgtccc gctgcgattc cggcgtactg
    12121 caacgacgcg atcggtggct cgcagcgacg ggtgcctgtg tagtacccga gataagtcag
    12181 ggccgcaggc acgtaggtgg gcactttctc gtccatggtg tgacccaatg cccagcgaat
    12241 gttcagatca gaggtgaagg gaacaaaggg gaatccggga aggcggtact gatcctcgct
    12301 gtacaacgca aattcagcgg gatcgacgac ccgtgagccg gccagttcca gcgctgatgc
    12361 actgctgcgg accagatcct cggggaccac gttgccgcaa tatctttcga cggcctcacc
    12421 ggtcgccgcc ccgcgagctg ctgcatcgtc gcgtatcgaa gccccgaatc cgtaagggtc
    12481 cgcgcgaaac agtgaaccgc tgccgccgaa gtttctggtg tcggccaccc tcgcggccca
    12541 accgacccag cccgtcggca tgtccgagcg aatgtgtggt tccagtgagg tcagcacgcc
    12601 gctccgtgcg tcgaccagca agtcatccac cgtcagttcc tccgagtatc ggcagggtca
    12661 acgacccgga aaatgattgg tgcagtgcgg tactgcgtgt tcctcgatag cgatcaccgt
    12721 ctccgagatt gcgtgcgagg cgggggaagt ccgatccggc gatccgcagc gacaagacat
    12781 cacccgcgcg cacagtgtgc aacacgggat ccagatcgat ggtcaccatc gtcggctgca
    12841 ggctgacacc cgcgccacgt gcgatcgatc tggtaactcc agcgggatct acgacgctca
    12901 gttcggcgat ccaatcggct tcgccctcgg gtgaatgcac tttcagctcc accgatggtg
    12961 ttccggagag tacggagtcg tgcttgatat cgaaagtcaa gacaacacag ttgtttcggt
    13021 cccgtgaggc gtcatacagg aagctgtagg ccgcatcctt ccgatctggt tcgagatgaa
    13081 cgcgattcgc acccgtgaca aacggttcgg tcgaccattc gccgacaccc cggtcgaata
    13141 cccgattgat ggtcaggggc cgcgcagcga ataccgattc catccactcg acctgaaggc
    13201 ggccgaaact tgtctcgccg acccttccag ggcggaggtc gtgcgcccag gggcccacga
    13261 tcaaactctg cggcccgcgc cccacggacg tgaagtgccg cagtgtctcc cgaatcatcg
    13321 catcgtccca accgccgatg tgcagcccgg cgatgtcgag ttcggagagt tcgtccgcgg
    13381 acaccagatc atcgccaccg aagtcttcgc gtttacgagc gcgaaggatc ggcgtcaacc
    13441 agcccggtga atcggaggtc agaccaacct cctcgatcat cgactgcacc gggagatgtt
    13501 ccagcaaaga cgaatccgag cgcatcaggg cagggatgaa accctcacga gaggaagacg
    13561 aatctccgtg ctcgccccac cacgccagat gctcggcgag gagaagtatc gccgagggat
    13621 cacgtttgac gcggtcgctt ccgatggtcg gcaccttgga gacgacgccg tctacacgaa
    13681 atgaccgatc ggcgctgttg gtctcggtag caaatgccca ggcggttccg gccgcatacg
    13741 aagccccgct tgcgatgacg cactccggtg tccacggctg atcctgcagc cactcggcca
    13801 gggcggcgct gtcctcgcgc tcgtggacgt acggttccca agagccggtg gaatcgtgcc
    13861 gtccgcgtac gtcctgcgag atgaatgcaa ttcctcgcga tcgccattcg atcccctccg
    13921 ccagatgcca tccacgcccg tacggggtgc ggatcacgat cagtccccgc ggtgaagaat
    13981 ccggtgggag aagcacatcc gtagccaacg aagaaccgtc tgctgccggg atcttcacgc
    14041 cgagtgagat caccggagcg tcggcgcggg ttcgagaacg ccgccgggca gtggtagcac
    14101 gggatggcga gtcatcatga gggttcgcgg attcatccgg atctggtggt gaaggtgtga
    14161 tggcggtgcg ccatgtacac cagccacgac gtccgaacat gcaagcgcac tggccattgc
    14221 ggctgcggtg ggttcaagtt cgagcgggcg aggttcgctg ccggcgaggt gattccacag
    14281 tgcctgcaga tgatccggga cgcgcgacgc ggcaagccgt cgaccgcaga cgtcccggta
    14341 gcttgcgctg ccgataccgt cgaagaaggg tccgatgcag atctcaccca gctccgcgtg
    14401 gacgcgttgc cacggtgttt ggtttcggcg gcaccaggta tcgagttccg accactcgtc
    14461 gtgaggagga gcaccggcaa ccgacagtac gaggtccgaa gacgcaacgt cgtgttcgat
    14521 tggcgcagta gtggatacga cctcgagatg cggaagagcc ttggagagca gggcgatgca
    14581 agcatcggca acgggcccga tcccgtccat cagcacacgc tgtgggcgcg gaatctctgg
    14641 cacttgacct ggaacagcca gcacgccacg agagacgagg gcgtcggcga tctcgatagc
    14701 tcccgggccg agcaccgaac cagagcgcct gagaaagttg tcgagttccg cgaggtcttc
    14761 ggccggcgcg ccgatcgtga ccgcgttctc gtccggtgtc aggtaatgcc aaacaccgtc
    14821 cggggtcgga tacagctggt gtccgtcggc gagggcgtac acggatctcc ttgtcggtgc
    14881 ccgcacccga cgagtcggat gcgggcgggg tcatcggcag atcagactgt cgaaacagtc
    14941 tggatcaggg gaggtttcag ctctggaagc tgaacgggtt gtcgacgagg gcgttggtgc
    15001 ccacaccctg cagggcgtgt gcggacgttg cctcggcaac cggctcgaag gtgaacgggt
    15061 tgtcgacgag agcgttggtg ccgacgccct ggagtgcatt ggccggagcc gagttggaga
    15121 cgctgtcgaa cgaaatgttg ctcattgtca tcccttccgt aatggaaacc atttccatta
    15181 cgatgccacc gtacgaaaga tcgccacgga gagcaacagg tacaagagag tgcatacatg
    15241 agcgagaccc cgacgacggg atccgtcgaa gcgcaaccac atgtctttcg ggacagatcg
    15301 tttcgattgt tcttcacggc tcgtacgatt gccgtagccg gtgcggcggt caccggagtg
    15361 gccatgccga tcctggtgtt cgacatcagc cggtctccgt ttctcacctc gctcgcggct
    15421 gcggggacgg ttctgccgta tctcgtgttc ggcttgttcg ccggcgccgt ggcagaccga
    15481 gtcaaccggc ggacggtcat cctgtgtgcg caggccgtag ctgcacttgc tttggcgagt
    15541 attccggcag cgcaggcact cggcgtattg acggcgtggc atgccgtcgg cgtatcgatc
    15601 tgcatcggaa cgtgtttcgt gtggttcgac gccgctgctt tcggagcgct gcctgctctg
    15661 gtcggtgggc agaggatacc ggccgccaac agtgcgctgt ggacgtccag cacgctgatc
    15721 gatgttgtct ttccggcgat agccggcgtg cttgtggcct cgatcggccc ggcctacgca
    15781 ttgggtgctg atgcactggc ttacatactg gccgggctgg ccatggcctc gatcggagcc
    15841 tcgttttcga ttactcctgc ggcgccgaag aagtcgggaa ccggaattgc gcgtgacata
    15901 cgcgaaggcc tcaacttcct ctggcagtcg ccgcttctgc gggccttgac cggcgtcggc
    15961 ttcgtcaatt cgctgacgca gggtgcggtt acggcgctcc tggtggtgta cgcatccgag
    16021 aggcttggga tttcgacgtc gagtccgatg atcggcgccg tgtggacggc cgtctccgtg
    16081 ggtggagtgg tcggggcagt cttgctccca cgcctaccgg cgcagtggcc ggtcggggcg
    16141 atcacggtcg gggcgctgac catcggcccg gtggtgctgt tcgtcgttgc gacaaccggc
    16201 aataccggcg ccgcgatcac ggcgctcgtc gtctactccg gctgtgcgac cgtcaccatc
    16261 ctcaatggca tcggtgcacg tcagcgcctg actccggatc gtctgcaggg gcgcgtgaac
    16321 accacggcga ggatggtcgc ctggggtggt tcgccggtcg gcgccttgat tgccggggca
    16381 atcgcaggac gctgggacat cggcaccgcc tacctcgttg cgtgcatctt tgcgctggtc
    16441 ggggcgctat tcgcgtgggc gagcgcgctg cggaccgacc cttacccgca cagatgagca
    16501 tgtgactatt aatgaaaacg actgtcgtta tggttagatc cacctgttca tgactgcgaa
    16561 ccccaccgac tcaggagtgc gatgacgctg accagcgagg cagcaccacg agtgccgtcg
    16621 cgtccacatc ccgtcggcga gcgcgggtac gtcccgtttc tgttggccac ggcggttgtg
    16681 cttgtcgcgg tctccaccgt cgcggtgtgg tcgggtgccg cgtcggtgtc ctttgccgac
    16741 gtgttcgcgg tgttgtacgc acacgtcggc ggtccgccgg tcgacccgct gctcgatcgg
    16801 atcgtgtggg gattgcgggt accgcgcatt ctgattgcgg cattggcggg cgccggattg
    16861 tcgttggccg gcgccgtgct gcaagcgttg gtgcgcaacc cgattgccga tccgtacatt
    16921 ctgggcgtgg gttccggagc atccttcggt gcagtactga tcatgacgac cggcatcggc
    16981 accggcctgt cgatcggtgt cccggtggca gccttcctgg gggccatgat ctccctgatc
    17041 gcggttctcg tactgggtcg gcgagaggga atgctcgtcc cgctgcgcat ggtcctggcc
    17101 ggagttgcca tcggctatct gctctcggct gcaacaagtt ttgtgcagtt gcgcgccgat
    17161 ccgagtcagc tttcgggagt gctcttctgg ttgctgggtt cggtgagcgg ggccagttgg
    17221 tcggatctcg gtgtgcccgc cgcggtgatc accgtctgtg cggcaattct gttgacacaa
    17281 tcgcgccaac tcaacgcgtt ggccatggga gacgagagcg cgcaatcggt cggcgtggac
    17341 gtgcgccgta ccaggttgct actactggtg atcgcgtcgt tgctgaccgc ggttgtcgta
    17401 tccgttgccg gcggaatcgg tttcgtggga ttgctcgtgc cgcacgccgt acgacttctg
    17461 gtcggatccg atcacggcaa gctgctcccc gcgaccgcgc tggttggtgc caccttcctg
    17521 gtgatcgtcg atctagcggc tcgaatgttg gatgcgccca acgaattacc actcgggatc
    17581 atcaccgccg gattgggtgc accattcttc ctctggttac ttcgacgcga cggaggtgcg
    17641 cagtcatgag attgtcggcc agcgggattc acgtcgttcg gggtgggcgc ctggtggttt
    17701 cgggtgtaga tctcgaagcg cccgagggaa gcgtggtcgg actcgtcgga ccgaacggca
    17761 gtggaaagtc ctccctcctg cgtgcgttgt atcgctcgat gaagccgaga agcggaatcg
    17821 tgaaggtcga cgaggtgaat gtttgggacg atctctcgcc tcgatcggcg gcacgcatca
    17881 ttggtgttgt ggggcaggag cattcatccg atttctcgtt cagcgtccgc gaggtggttg
    17941 caacgggccg gacgccgcat cacagcgcgt tctctcgact cggtgagatc gaccgagaca
    18001 tcgtcagcgc cgcactggtg cgaaccggca tgcagggctt tggatcacgt ctcttcgccg
    18061 aactgtccgg cggagaaaag cagcgtgtga tgttggcccg ggcgatcgct caacaaccgt
    18121 cggtgctggt cctggacgag cccaccaacc acctcgacat ccgtgctcaa ctcgaattga
    18181 tggaattggt cgccgaactc ggtaccacga cgattgtcgc gatccatgaa ctcgccttgg
    18241 ccgcagcgta ttgcgactac gtctgtctgc tctccggcgg ggtagttgtc gcgacaggac
    18301 caacggccga ggtcctcact gaggacctgc tgtccgaagt attcggggtt caggtgcatc
    18361 tcggcactca tccgttgacc gggcgccccc tgctctcgtt cgcccctcct ctcctaccta
    18421 cgaaagaagc agtctcttga aaacctcgat acgtactgcc gcgctgttct gctcggccgt
    18481 ggccaccacc gccgtactga ccgcgtgcgg gaactccact gccgattcgg cggcagcctc
    18541 gtccgagaaa atcaccgtca ccaattgtga tcgcgacatc acgttgccca agactgccga
    18601 aaggatagtc tcgctgtatc cgtcgatgac ggagcttctc attcagctcg gtgctgccga
    18661 ccgcattgtc ggacaatcga acaccgacct ctctcctccc agtcccgaac tcgctgatca
    18721 gttcgcggcg gtgccggtac tgagcaccgg agttcccgcg aaagaggcct tgctcgacgc
    18781 ccgtccggat ctgatcgtct ccgacgggga atactggttc gacggtgacc gattgcagac
    18841 catggacgaa ttgcgcgacc tcggcatccc gatcttcgtg aacagcgggt attgccacaa
    18901 ggcagtcacc gagggacgga tcgacgacgt ctggtccgac atcgacggtc tcggtaccct
    18961 gaccggaaca cgtgaggagg cagcaactct cctagcagac ggcaagaagt cgctcgcagc
    19021 aaccgaggca tctgtcgccg ggaaagagcc ggttcccact gtgatggttc aggtttcgga
    19081 gggacagtcc tatgctctgg ccaggggcct ctacagcagt gtgctcgagg ctgccggggg
    19141 aagcaatctt ttcgagaacg accttcccga cggaaagtac ttcggtcagg tagccaccga
    19201 atcggtgctc gcgaagtcgc cgaaggctgt cctcgtcgtc tactccaccg agtcggctcg
    19261 ggaatccacc ctggatgctg cgcggacggc atttgccgga acccccgccg cgacatcgaa
    19321 tgcgatcttt gccgttccgg aggcgtggtt cgccggcgag ttggtctcga tcgacggggc
    19381 cggcgaggtg tctcgcctgc tgcacccggg ttcgtgaccg cactcgagcg aatcgaggcc
    19441 gtcgtatcgc tgcatgcagc gttggaccgg acggtgagtc cgtcggagct accgttcgac
    19501 gagcacgcac tgccgccggt gacgtgtgaa tccgtggaac tgccggccgc gacgccactg
    19561 ccggtctgcg ggttcgcgga cgtcttgcag gcacgacgga gccgctacga ccctgcacag
    19621 acggcactcc gagcaggcga gctgtcaaac gtgttgcacc acagccttgt cagcagcccg
    19681 acggcgggcg ggatgcgcga actgacgctg tcgtttgttc tcagccgacc cggagacgag
    19741 ctcggagccg gggtataccg atatgcccga ggccgtgccg aagctgtccg gccaggcgac
    19801 gtgcgagagc accttcgagc gagccttctc caacccgagt tcgtcgacgt gttcccggtt
    19861 cttttgtttg tggtcgccga cgtcgaagct ccgctcgaga agtacgcgat gcggcactac
    19921 cgcacgatgc acgtggatgc cggtgtgctg gttcagaatc tgtacctcgt gaccgaggcg
    19981 atgggacttg tgggctgcgc catcgcagga ttcacggatg cgcgagtggc atctctgttg
    20041 aatctcgcga cgacgcagct tcccgtcatg gcttttgccc tcgggaggcg cagctaggtc
    20101 aggcgaggat gcgcgccttc tgggtctcga actcggcctc ggtcaatact cccgcattct
    20161 tgagttcgcc cagcttggtg agctgttcga gcttcaagtc catcgatgct gccggagctg
    20221 cctgcggtgg caggggtggt agatcgggaa tcggaggcac cggctgggcc tgcgctgcgc
    20281 gagcctgatc ttcggcggcc caacgggtcc gctgacggcg ctgaacattg ccgtgaatgg
    20341 agcttgcgac ggctacccgg ccggctcgcc tcaagaaact catgcgtcct tctccgtatt
    20401 gcctggtgcg gtgttgtcga gtgcggtggc aagttcgtcc aagctcaggt gaccttcggt
    20461 gacaatcttt gcgccgctgc gtgtccacgc gtcgatcacc ggcagtatgg ccagttcctc
    20521 gtaaacgagc acggcggcaa cgctaccggt ggccaactcg tcaccaacgg cggcgatgtc
    20581 gccggcgtcg agcagtccgg aggctgcgcc gtcgaactgc gccagatcga aatctgcgag
    20641 ttcgaaggtc gatgccggta cgacggccac tgatccatcg gcggctttgg tgacgaactc
    20701 gaggtcgagg atgcggatca cgccggagtc gacgagaatg agcagctgct cgaatcctgc
    20761 ggaggtcggt gcaccgccgg gaaactcgac ggcaacgtat tcgatcggac cgaattggtc
    20821 ttggttggac atcggttact tcttgccctt cgtgggttgc ggttcttcca gagcaggtac
    20881 ttcgttgggc atgcggccgg ccggaatgat ggcgagcagg gagagtccgg cgaggacgag
    20941 tagcgaggtt cgcagggcgc gcaagcgcgc ttcggtgttg atccggatgg cttcgtcgat
    21001 ctgtgcttgt gtcgccgagg tgttttcgag cgtcacgacg agttgatcgt tggggacgaa
    21061 gttgacctgg tcgagattga tcccggactc gaccttgagt gatgccggga tggtggggtt
    21121 gtcgatcagc tgcgagctga cgagggaacc gaggattccg acggcgaaga cgctggccac
    21181 cgcgatgccg acgctgccgg acatgttgtg taccagtccc cgccaggcac cgacgtcgcc
    21241 ggccagttcc ttgggggctg cggtgaggag ggtgttgaac accagcgcaa cgatggcgcc
    21301 ctgcccgagg ccgagggtga tcagtccgat gacgacaaag atctgatgcc agtcgccacg
    21361 aatggtgaag gccaacaaga tgagtccagc ggcaacgacg acgaacccgg ctcgtgcgat
    21421 cagacgcggg gagtacgtct tgtacagacg cgcgacgacg gtactcgcga tgaagatcga
    21481 aagtgtgtac gggatgatcg agaacgacgt ctgcaagctg ctgcggccct ggatgatctg
    21541 catgtacagc ggaatgagga agttggccgc ggttcccacg aacatcatcg tcgccatgca
    21601 aatcgtggtg gcgcgctcgg cgccggtctt gaggacgtcg aggttgaaga gctgaggctt
    21661 gttctgcgcc ttgcggcttc gcgtccactg gaagaatccc tgcgcgcaga tggtgccgag
    21721 gacgatcagg atggccgcgg gtgaaacacc gatgaccgag aacggcgcag cgtcggtggc
    21781 caggatgacg ccccacgagt tcaggccgct gaaaccgaag ctgagcagga tgacggcaac
    21841 ggcagcaatg gcggcgccgg cccagtcgat ggtgatgtcc ttctgcgggg gaacaggttt
    21901 gacccggaag ctcaggatca ggttgaccac cgcgagagcc acgacgaggg cgaacgagta
    21961 tcgccacccg atcgtcgtcg cgaaggaacc ggcgatgagc agcgccagca caccggccgc
    22021 cgggattgct gctgccaggt aaccgatggc ctttgcctgc tgatcgccac tgaagttcgt
    22081 ggcgatgaag accgtcaatg cgggagcgat gagggcgatc acggcgccgg atgcagcttg
    22141 cgccacgaac agcattgccg ggctctgact cagggcgacc gcggccattg cgaggccgtg
    22201 aatcgcgacg gcaatctgga agaccagacg cgttccgtaa cgggcgccga tcttggcccc
    22261 caacagaatg aaggcagcca tggcgaaggt gcccgcggtg atcgcggtgc cgacacttgt
    22321 tgcgggcgtg tcgagatcgg tggtgatgcc ggccatcgag acggtcaggg cgttgacggc
    22381 gaacgacgcc tgaatctggg tgaggaccac cacgatgagt ggtagccagg aggcggtgct
    22441 cacggcggcc gttgtggcgg ccgcgccagg ctttacggac atgatgggtc acgccttcct
    22501 cgacactgcg tgtactcgcg acgtgcccgg atcagccacg cacggctaca ttagccggaa
    22561 ttgtgctgaa tggtcgcctg caagtggttg gtttcttcgc gatagaccac catctcccgg
    22621 tgcaaggcgc gccggaagcg cggttgctcg gccaggagta cggccagcac ggtcagcaac
    22681 agccacgtcg cggccgcgct cgcgaggagc agcaggaccg gaatccacgg accgcccatc
    22741 tgctcgagca gcgtcgtctt tgcccagacg cgccagtaga gcatcagatt gacgatcagt
    22801 ccgacaccgt acgagatgac gaaggacagc aggaactgct tccacgtgcc gtcgtggcgc
    22861 cgcgccgtca tcggttctgc ccgcagcggc aagctcaccg acatcacgtt cgcgaccccc
    22921 aaccagagca ggatcatggt cagcacctgg ccgcacgcct tcaccaggtc ggcactgctt
    22981 ccggagcgcc acgcgaggac ggcgctgagc aggaacccgg cgctgccgac gagaagcagc
    23041 atcaccgcgt tcttcgcgac cagtacgtgc cagagcctgg ttccaccgga caacgcagca
    23101 cggacgcggc cggcgtcgaa gctgagcgca ttggtgcaca cgacgcttcc gaccacaccc
    23161 gagagtgcgt acagcgcaag ataaggcagt cgatcttcct tggcgtccca ctggaagagg
    23221 cgaatgaatg ccaggtacgc caagcccagt ccgaggctca gccccagccg aaacgcgatc
    23281 gaccgaggct taccactcac cacgtgccgt gcttcctcac ggatccggga gccgagatcc
    23341 tgcacgtgcc ggacgacggg gttgcccgag ttcagcggga cgtaaccgcg gatcgcggcg
    23401 gcgacggtat cggtgtcacc ggcatcgagc gcggcgacgc gtgcttcgag aaccgcaagg
    23461 tgggcggcgc gcaaggctat ccgtgcggtg gtcaccgcgg cgacggcgtc ggcctcggcc
    23521 tgcgcggcgg tgccgatgcc ggcgtcggcg ggcagtggcg gctccaacgt cgtgatcagt
    23581 tcgagttggc gcgccatgtg cggcgacggt gacaacccgc tgtacgacgg tcggctcagc
    23641 gctgatcgtt cgtcgtcgag cgaatcacgg acggccgcgg cagccttgcg gacggctgcc
    23701 gggttgtgcc agcgcaccga ccgggcgtca cgctcggcgg cgacggcccg ggaggcaacc
    23761 tcggtcagat cctcgaccgc tgtcaatgtc tgctccactc ggtttaggtt ggtttcatga
    23821 ccaccaactc ggaaaaggaa gatctccagc ggtacctgca ggcagcacgt gatgcgctcg
    23881 tctggaagct cgacgggctg tcggagtatg acattcggcg tccgatgacc cggacaggga
    23941 caaacctgct gggtctggtc aaacacatga tcggcgtcga gctcgggtat ttcggcccga
    24001 cgttcggccg tcgggttccc gatctccccg cgtggttgcg ctcggaggaa ctcaacgtcg
    24061 acatgtgggc ccgcgccgac gagtccactg ccgacatcgt cgaaacctat cgccgcacct
    24121 gggctttcgc cgacgccacg atcgaggagc acgatctgga cgcccccggc ttcgtgaagc
    24181 actggccgga ggatcgtcgc gacgtcacgc tgcaccagat actcgttcac gttgtcaccg
    24241 agacccatcg gcacgccggc cacgcggaca tcgtgcggga gctgatcgac ggcgccgcgg
    24301 ggatgaaagc gggcgacaac aatctggctc ccggtgatga ggcgtggtgg gccgagtaca
    24361 ccgaccgtct ggagacggcg gcacgcgagg cccaccacgc ctgaactact cgaataccgc
    24421 tgctgcgccg atcaccacga caacgatcac gaagttgatc agtagcagtg gccagacgaa
    24481 acgcaggaac ttgtcgtagc cgaccttcgc catggccaac ccgccgacaa cgacgacgtt
    24541 ggtcggggca accatcagca tcaggccgtg gcccatctgg aaggcggtga tgacgagtgc
    24601 tcggctgact ccggcgaagt cgcccagcgg cgcgagcagc ggcatcgcca gggtggcgtg
    24661 accagaactg gacgggatca ggaacgccag cgggatgttg acgagcatca ccaggatcgc
    24721 gaagaccccc gccgaagcgc cgctgaccaa ttgctccatc gcgttgagga tggtgtcgag
    24781 ggtttcggtg ttggtcatga tcaccgagac gccgcgagcg agcaggatga cgatcgccgg
    24841 tccgaccatg tcgccggctc cacgcgtgat cagggagacg atcttcttct cacccatctt
    24901 cgcgactatg ccgacgagaa cggcggcgag gatgaacagc atcgccaatt gcgggaacca
    24961 ccagttcaac tcgaaccagt agggctcggt tgccgtgacg tggtacgcgt cgtactcggc
    25021 cggaccggta gtggcgccga agatgctcga ccacgggatg acggagaaga tcatcagtcc
    25081 gaaggtgagt ccggtgatga gcagtaccag cttctgagtt ccggtgagct tgccgtcgat
    25141 gtccaccggc tcggccggct cttcgtcttc gtcgtccgcg atgtcgaaac cgacaagcga
    25201 cttggacgga tccttcttca cctttgcggc gtagcggaga acgaatacca ctgccacagc
    25261 ggtcaatacg atccacagga tcacgcgcag cacgatgccg tcaccgatgg agacgcctgc
    25321 ctcaccggag gcgacgccga tcgagaacgg attgacggtc gacgccatgt ttccgaccag
    25381 agcgccgagg atgatcatgg tggccgcgac catgcggtcg taacccagtg ccgtcatcag
    25441 cgggatgagc agggcgtaga agccgaacgt ctcgaccgag aagcccattg tcgaaccgag
    25501 cagcgagaac agcaccatga tgacggtgat gagcaaccag cccttgtcgc tgagcttggt
    25561 agccagctgg gagacagcgg tttccagact gcgggtggca aagctgaccg agatgaacgc
    25621 accgagcgcc atgatgaaga ggactacgcc gaccgaaccg aagagccgtc cgatgttgtc
    25681 ggtgtcgacg aacccggtga tcgaatcctg gacgccgtac aggccgttca cgggggagag
    25741 gatcagttgc tggattcgtt cccagaacga gagcggagac gtgacggttt cgaagctgcc
    25801 gggaacgggt gagccgtcca cgtcgacgcc gaagcgtccg gccggaatga acagtgccgc
    25861 aacccagacc agaatggtga cgatcgcgag catcgtgacc gcaccgggaa actcgaactt
    25921 cttcttggcg ggcgtttgcg cggatcccgt atcggtctcg gtgctcattt cttcccctcg
    25981 aaggtgtgtg cgtactcctg gaagaacagt gctttggcga cgacggcctt ctcgagctcg
    26041 tcgagcagga cgcgttcgtt ggggccgtgg atgttcgcgt aaccgtcggt ggcgccgaac
    26101 aacagcttct cggcggtggg cactgctgta tccaaggcca tcacgagggg gatcgagccg
    26161 ccgcctgcca tcagcccggc cggttcaccc cacgactgcg ataatgcaga caatgccgcg
    26221 tcgaaggccg gtccaccttc ggctgccgca aacccgtcgc cggtttctcc cgcggtgaca
    26281 gtcagttgta aaccgaaggg gcgcagggct tccaggtgcc ggaccagagc agcctgcgcc
    26341 tcgatggcag gttggcgcgg gtgtacgcgc agattgatca cggcgcgggc agtgcttgcg
    26401 acggcgttga ccgcaccgtc cacaggggga gcgtcgattc ccgtcacggt gatggccggg
    26461 cccgaccaga tgcgttcgcc gatgccgccg gttccgagca gcggaagccc gtcttggatc
    26521 tcggcgaggg tgcggaactc gtcctcggtg tatgaactgc cggtccacgg ttcgcgcagg
    26581 aggccgtcga tcgccacgtc accgttgtcg tcgtgcagcg acgccagtgc gcggatgagc
    26641 gcgaggcggg cgtccggtgc ggcgccgccg tagaggccgt tgtgcttgtc ggctccgaga
    26701 gtggtgagtt cgacgatcac ctgggccgat ccgcgcagtg cgacggtcag ggtcggtgat
    26761 ccgggccgaa cgctcccgac gtcggcgatg accattgcgt cggccgcaaa caattcgggg
    26821 gcttccggcg gatagttgtc gaaggggctg ccgaattctt cctggccttc gatgacgagc
    26881 ttgaccgtca ccggcggctt tccgtcgaag acgcgaagcg cgccgatcat gccgatgacg
    26941 tttgccttcg aatctgccgt accgcggccg taaatcgcgc cgtcacgctt gctcggttcg
    27001 aaaggcggtg aatcccagag ttcgacgtcg tcggcgggaa cgacgtcgta atgcgaatac
    27061 atcaatacgg tcggggctcc ctctggaccg ggaactgttg caatgatgac cggcgcagtt
    27121 ttacctgtta tttcgagttt ctctatcttc gtgactccgg acttctccaa tagagaaacg
    27181 atcaggtcgt gagcctcgaa caggggctcg ctggggaaac cttctgttgc tatcgacgga
    27241 atacgaacaa gttcgacgag ttccgactcc agtgccggca tcaaagctgc aactgtttcc
    27301 ttgattgtgg aataggaggg cgaggcggat tcttccggca cggaattgac tccttctggg
    27361 aaaggcgaaa aacattagag gcagagtctt acacccgata tgcggggtgt gaaagggtga
    27421 cccgaacaaa aagccgaagt ggggcgccgg gctcgcgatt cttgacattg acgtcaacgt
    27481 caacacatac tgtgacggtg accaccagtg aaacgcagga gcgagcgcgg acagcccgca
    27541 aactcggcga cggtccacgc cgtgccggac tgctcgacac cgctgccctc tgcttcggcg
    27601 aactcggata cgacgccgtg acggtcgaga cgatcacgac cagggctgat gtgtcccggg
    27661 cgaccttcta cgcgtacttc tcgtcgaagg acgaggtctt ccgcgccgtc gccgaaatga
    27721 tgtgccgacg cttcctcgac gctcagcaca tggagggccc ggcggccgag gatctacgcg
    27781 aagttctccg aacgaccacg tcggcgttca tcacggccgt gtacacctac ggtgacctgc
    27841 tcgcggtgat cgagcatcgg gcgcgggtgg attccgaggt cgagcgcagt tggtcggcgg
    27901 ttcgcgaaaa gctcgtgagc cgctacgtcc gctttgtcga acggattcga caggttcacg
    27961 acgtagatcc ctgtgtttcg cccccggtgc tcgttcagat gatctcggac gcacagatgg
    28021 ccggtggagc acgactgagt aaggcgagtg tcgaagagca gaaccagttc attgcagata
    28081 tgacgacgat gtccgagcgg ttgatcgggt tcgaagagtc gaaatagatt tcttttacga
    28141 atggagtgat cggtggcaga acaagacgtg ctcgaagcgg ctctggcgga gatctctgcg
    28201 ctgcaacaag cgcattggcc cgccggcatt ccccgcgccg tcgagtatcc gctcgaaggt
    28261 gggggacttg tcgattactt gcggcattgg gcgatcgagc ggccggatac tcctgccatc
    28321 atcttctacg gccgggtcat cacgtattcc gaatacgacg agctttcgga tcgttttgcc
    28381 ggatggctgc tgtcactcgg agtcgaacgc ggcgatcgcg tcggcgttca cctggtcaat
    28441 tgccctcagt tccatatcgc gatgctcggc attctcaagg tcggtgcggt tcacgtgccg
    28501 atcaatccac tcttccgtga acatgaattg attcacgaac tcaacgatgc cggcgtcaag
    28561 gtcctactga cgcagaacac cttctcgaag ttggtgaaga aggttcgctc acagactcca
    28621 ctcgaacacg tcgcgaagac tgcagtgtcg gacatgctga cggcgatccc gaccgtcgaa
    28681 ctgcccttcg aggtcgacga tccgcgcctg agcgactggc agtcgatcat caccagtgag
    28741 cgggcgactc ctgtcgccac cgaactcgat tccctcgccg ccctgaacta cacgggcgga
    28801 acgacgggaa tgcccaaggg ctgtgagcac actcagcgcc acatggttta caccgcggcc
    28861 accgcgacgc ttgcgggcgg tgaccaggtg ggtgccaatc cgccggtgtc cctggtgttc
    28921 ttgccgatct tctggatcgc aggtgaggac ttcggcatcc tggttccgct cgtcaacggc
    28981 ggaaccgtgg tcctgctgaa tcgttgggat gcggagacca cgctcgacgc tgtcgaggct
    29041 tacggcgtga cctcgctggt cggaactgtc gacaattacg tcgaactgat ggacacgcca
    29101 ggattcgcgg agcgaaatct ctcgacactc cagaacgtca tggcagtttc gttcgttctc
    29161 aaactcgatc cggccacgcg ccagcggtgg cgcgaggcta ccggcggcgt tctgcgcgaa
    29221 gcgagctacg gcatgaccga aacccacacc gcggacacga tcaccctcgg cttccaggac
    29281 ggcgactacg acctgaaaag cgagccggtg ttctgcggaa ttccggtgcc cggcaccgac
    29341 gttctgatcg tcgatcacga cggcaggccg gttcccgtcg gcgagcacgg gcagatcatc
    29401 gtgcgcagcc cgtccatcct ttccgcgtac taccgcaacg aggcggccac cgccgacgcc
    29461 atccgtgacg gctggctgca gaccggtgac gtcggaaagt tcagtgagcg tggcggtttg
    29521 cactatttgg cgcggaacaa ggaaatgatc aagaccaacg gcatgagtgt ctttccctcc
    29581 gaggtggaag cgctgctcat gctgcacccg gcgatcgaaa aggctgcggt ggtgccgaaa
    29641 ccggacccgg acaaggggca ggtggctttt gcgtttgtcc aactggtcga gggttccgac
    29701 actgcggccg acgagatcgt ctcgtgggcc aaggagaaca tggccacgta caaggtgccc
    29761 gaagtggaag tgctcgaggc gcttccgatg actgcaacag gaaaggtgcg caagggcgat
    29821 ctgttcgagc gcactcaggg ggacaagtga gattgctgat tgcgaaccgc ggcgaaattg
    29881 cgctgcggat cattcgaact gcccgtgaac tcgggatcga gacggtgtcg gtgtacgccg
    29941 aggacgacgc gtccagtccg cacgtcgcgg cggccacgga gtcggtgccg ctcggagcgt
    30001 cgggcgcatc cgcgtacctg gatcagagcg cactgctgaa gatcgcggcc gaaacgggcg
    30061 ccacgcacgt gcacccgggc tacggattcc tcagtga
//
