LOCUS       NZ_CP114040            20207 bp    DNA     circular CON 26-AUG-2024
DEFINITION  Nannocystis poenicansa strain FL3 chromosome, complete genome.
ACCESSION   NZ_CP114040
VERSION     NZ_CP114040.1
KEYWORDS    RefSeq.
SOURCE      Nannocystis poenicansa
  ORGANISM  Nannocystis poenicansa
            Bacteria; Myxococcota; Polyangia; Nannocystales; Nannocystaceae;
            Nannocystis.
REFERENCE   1  (bases 1 to 13228663)
  AUTHORS   Ahearne,A., Stevens,C. and Dowd,S.
  TITLE     Minimal conservation of predation-associated metabolite biosynthetic
            gene clusters underscores biosynthetic potential of Myxococcota
            including descriptions for ten novel species: Archangium lansinium
            sp. nov., Myxococcus landrumus sp. nov., Nannocystis bai
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 13228663)
  AUTHORS   Ahearne,A., Stevens,C. and Dowd,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-NOV-2022) Biomolecular Sciences, University of
            Mississippi, Faser Hall 407, Oxford, MS 38655, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2021
            Assembly Method                   :: IPA v. 10.1.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 250x
            Sequencing Technology             :: PacBio Sequel IIe
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_026965555.1-RS_2024_08_26
            Annotation Date                   :: 08/26/2024 12:45:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,229
            CDSs (total)                      :: 10,129
            Genes (coding)                    :: 10,068
            CDSs (with protein)               :: 10,068
            Genes (RNA)                       :: 100
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 9 of 61
            Pseudo Genes (incomplete)         :: 52 of 61
            Pseudo Genes (internal stop)      :: 2 of 61
            Pseudo Genes (multiple problems)  :: 2 of 61
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:28:22
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 12783613
            Orig. end                         :: 12803820
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP114040.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20207
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="microviridin"
                     /region_number="44"
                     /rules="(mvd or mvnA)"
                     /tool="antismash"
     cand_cluster    1..20207
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(mvd or mvnA)"
                     /kind="single"
                     /product="microviridin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20207
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10207](+)"
                     /cutoff="20000"
                     /detection_rule="(mvd or mvnA)"
                     /neighbourhood="10000"
                     /product="microviridin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10207
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(mvd or mvnA)"
                     /neighbourhood="10000"
                     /product="microviridin"
                     /protocluster_number="1"
     misc_feature    772..785
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.84"
                     /tool="antismash"
     misc_feature    919..932
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.84"
                     /tool="antismash"
     misc_feature    1066..1079
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.84"
                     /tool="antismash"
     gene            complement(1182..1772)
                     /locus_tag="O0S08_RS49285"
                     /old_locus_tag="O0S08_49285"
     CDS             complement(1182..1772)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS49285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_49285"
                     /product="hypothetical protein"
                     /protein_id="WP_269036517.1"
                     /transl_table=11
                     /translation="MRPDTDLARRLALAEHIQRQWYPTWTSAWLKAVPASAVLEPIHRE
                     ALAEAGADPLALVAAKRTIVQTFLEDHFNRWTPEDAPYCTFVDGIWRAIDRAEMQACVD
                     GLLATARARISEVEAEEAAERAEAEQGGWLHAVRPSALADLMIDLDALRRWFTAELWAG
                     AEPTWFTNTGPGITDESAVIGLDDDIVTILWLP"
     gene            1958..3040
                     /locus_tag="O0S08_RS49290"
                     /old_locus_tag="O0S08_49290"
     CDS             1958..3040
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS49290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_49290"
                     /product="hypothetical protein"
                     /protein_id="WP_269036518.1"
                     /transl_table=11
                     /translation="MDVRELFPERDEIDEVQAAAIAAVAARLGMEREWLAEDDYIHEIV
                     GGAIDGERVAWVERRTKDDGGWVDVDYSLRMRVGEVLVREWVVDTYNPYFGCDVGYLRW
                     WGEAVVIVYREKHRTIACRLGLEGAPQLRAIGDGWTALGDVLLHESAARGLVERLQLPE
                     LRAATPMPGELANERMSVGACSRGHVLGESPAALQRQIAAGLPEVAAPIAELLVGALAY
                     RFWDPFPPLAATYEEAFDDHRWNTPCWLPYYLVCASPEAERQVLLAQLDAVAARPPEAF
                     AAEDNAAELACRHIAGRCAELAAACRAGRLPKGESCYFWVDWAQEAFAGAEALFPAGMW
                     KVWQTLRPRAHALQAFGESR"
     gene            complement(3120..3356)
                     /locus_tag="O0S08_RS49295"
                     /old_locus_tag="O0S08_49295"
     CDS             complement(3120..3356)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006413213.1"
                     /locus_tag="O0S08_RS49295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_49295"
                     /product="formate dehydrogenase subunit delta"
                     /protein_id="WP_269036519.1"
                     /transl_table=11
                     /translation="MDAHKLVRMANEIATFFESDPDPAAVSDGIAGHIRRFWDPRMRRA
                     LLLHIDEHAGEGCRPAVLAAIAANRKSLTPPAA"
     gene            complement(3368..6214)
                     /gene="fdhF"
                     /locus_tag="O0S08_RS49300"
                     /old_locus_tag="O0S08_49300"
     CDS             complement(3368..6214)
                     /EC_number="1.17.1.9"
                     /GO_component="GO:0009326 - formate dehydrogenase complex
                     [Evidence IEA]"
                     /GO_function="GO:0008863 - formate dehydrogenase (NAD+)
                     activity [Evidence IEA]"
                     /GO_process="GO:0015942 - formate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fdhF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer2_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134: flavodoxin"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019656227.1"
                     /locus_tag="O0S08_RS49300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_49300"
                     /product="formate dehydrogenase subunit alpha"
                     /protein_id="WP_269036520.1"
                     /sec_met_domain="Fer2_4 (E-value: 7e-24, bitscore: 82.9,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYSVKEPDAGTPERNSSEQVTLEIDGRAVTVPAGTSVMRAAADAG
                     VRVPKLCATESLEAFGSCRLCLVQIEGRRGYPASCTTVVEPGMKVRTQSDPLAKLRRGV
                     MEMYISDHPLDCLTCPTNGNCELQEQAGVVGLREVRYGFDGANHFKQAEKDTSNPYFDF
                     DPAKCIACSRCVRACEEVQGTFALTLQGRGFESKIASGDTDFKSSECVSCGACVQACPT
                     ATLVEKSIVERGQPDHSVVTTCAYCGVGCSFRAEVKGSEVVRMVPNKDGHANHGHSCVK
                     GRFAWGYATHKDRITKPMIRSSIRDPWREVSWDEAIAYAASEFKRIQAKYGRGAVGGIT
                     SSRCTNEETYLVQKLVRAAFGNNNVDTCARVCHSPTGYGLKTTLGESAGTQDFDSVEHA
                     DVIVVIGANPTDAHPVFASQMKRRLRAGARLIVIDPRGIDLVRSAHVEAAHHLQLRPGT
                     NVAVINALAHVVVTEGLHNEHFVRTRCEQPAYDKWKAFISDPRNAPEATEEVTGVPAAE
                     IRAAARLYATGGNAAIYYGLGVTEHSQGSTMVMGIANLAMVTGNIGRPGVGVNPLRGQN
                     NVQGSCDMGSFPHELPGYRHVSDPAVRALFAAAWGVDIDAEPGLRIPNMFDAAIDGSFR
                     GLYVQGEDIAQSDPNTQHVTAALESLECLVVQDLFINETAKFAHVFLPGSSFLEKDGTF
                     TNAERRISRVRKVTPPLAGKADWEATLALAEALGYPMQYTHPSQIMDEIARLTPTFTGV
                     SYAKLDQLGSIQWPCNDRAPEGTPVMHIDEFVRGKGKFVITEYVATQERVTRRFPLILT
                     TGRILSQYNVGAQTRRTANNTWHHEDRLELHPHDAEHRGIKEGDWCKIVSRAGETILRA
                     TISERMQPGVVYTTFHFPGSGANVITTENSDWATNCPEYKVTAVQVSPTGEPASTWQRR
                     FGEFSEEQDALLPRTDSH"
     gene            complement(6237..7772)
                     /locus_tag="O0S08_RS49305"
                     /old_locus_tag="O0S08_49305"
     CDS             complement(6237..7772)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012351922.1"
                     /locus_tag="O0S08_RS49305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_49305"
                     /product="NADH-quinone oxidoreductase subunit NuoF"
                     /protein_id="WP_269036521.1"
                     /transl_table=11
                     /translation="MTHIVYVPIDATARSVGADDVAAAIAREAAARGEPVQIVRNGTRG
                     LCWLEPLVEVVTPAGRVAYGPVDVADVASLFAADFLRGGAHPLAHGRTDDLDWLKSQER
                     LTFARVGVTDPLSLADYKEHGGLRGLRAALSAGTGAEVVEEVVRSGLRGRGGAAFPAGI
                     KWRTVAGTAGEQKYVCCNADEGDSGTFSDRMLMEGDPYLLLEGMTIAGLAVGADHGYIY
                     LRSEYPDAERTLLAAIDAARAAGWLGRDVLGSGRRFDIELRRGAGAYICGEETAMLESL
                     EGKRGMVRPKPPLPAISGLFGKPTVINNVITLASVPIILDRGAQYYADYGMGRSRGTLP
                     FQLAGNIKRGGLVEKAFGLTLRELIYDYGGGTASGRPVRAVQVGGPLGPYLPESKFDVP
                     LDYEAFAAAGGMIGHGGLVVFDDTVDMALMARYAMEFCAIESCGKCTPCRIGSTRGVEV
                     IDRIRTGERRGPNLALLRDLCDTMTHGSLCAMGGLTPAPVLSALEHFPEDFQR"
     gene            complement(7769..8242)
                     /locus_tag="O0S08_RS49310"
                     /old_locus_tag="O0S08_49310"
     CDS             complement(7769..8242)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011614621.1"
                     /locus_tag="O0S08_RS49310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_49310"
                     /product="formate dehydrogenase subunit gamma"
                     /protein_id="WP_269036522.1"
                     /transl_table=11
                     /translation="MSSDAIDQALAQSGHLPGGLLQVLHGIADRLGHIPPEAIGRVAAA
                     LNLSRAEVHGVVTFYHDFRSQPPGRHVLKLCRAEACQAMGSEALAGALERRLGCKFGET
                     SRDGAVTLEPVYCLGNCAAAPSLLLDGQLRGRLTGERLDRLVDALVAPTEERT"
     gene            complement(8301..9122)
                     /locus_tag="O0S08_RS49315"
                     /old_locus_tag="O0S08_49315"
     CDS             complement(8301..9122)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012122824.1"
                     /locus_tag="O0S08_RS49315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_49315"
                     /product="formate dehydrogenase accessory sulfurtransferase
                     FdhD"
                     /protein_id="WP_269036523.1"
                     /transl_table=11
                     /translation="MTTPDPRTRSVAAVLHRGDDVSARRDLLAVEDPLEIRVVTDDDPE
                     PRRLSMTMRTPGDDADLAAGFLFTEGVVRGREQIAGITCSEDHVRVDLAAGVRLPEAVP
                     KRSFVMTSACGVCGRASLDGLRARPPGPLTPGHPQLAAAVVPGLPGALLRAQATFAATG
                     GIHAAGLFDLRGELRLLREDVGRHNALDKLVGALLLAGQLPATDAVLLVSARASFELVQ
                     KALMAQIPIFAAVGAPSSLAVELALEAEMTLLGFVREGRFTVYSGGIRITR"
     gene            complement(9119..9526)
                     /locus_tag="O0S08_RS49320"
                     /old_locus_tag="O0S08_49320"
     CDS             complement(9119..9526)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR02664.1"
                     /locus_tag="O0S08_RS49320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_49320"
                     /product="nitrate reductase associated protein"
                     /protein_id="WP_371879588.1"
                     /transl_table=11
                     /translation="MAVRHQLDLCGIKLSLKEWVKLGPEQRSAVVALLDDSVHADPVGR
                     FDAAVVAMVEQRMGEPPARIAVDPAPPWADTARVPDDVATKAAAEGVALSPAQWAALAP
                     LQRFALYKLSRSSHKNENFVPACREFGILPQ"
     misc_feature    complement(9776..9789)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.18"
                     /tool="antismash"
     misc_feature    complement(9777..9788)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.01"
                     /tool="antismash"
     gene            10001..10207
                     /locus_tag="O0S08_RS49325"
                     /old_locus_tag="O0S08_49325"
     CDS             10001..10207
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     microviridin: mvd"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     microviridin: mvnA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033738.1"
                     /locus_tag="O0S08_RS49325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_49325"
                     /product="microviridin/marinostatin family tricyclic
                     proteinase inhibitor"
                     /protein_id="WP_269036525.1"
                     /sec_met_domain="mvnA (E-value: 8.3e-07, bitscore: 28.1,
                     seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="mvd (E-value: 1.4e-06, bitscore: 27.6,
                     seeds: 55, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANKQPGEALQAEALPFFAHLLSSQSDPAADGGGTKPAPTYHCLD
                     SPCTKKYPSDDDESTTWFSDSDG"
     gene            10284..11213
                     /locus_tag="O0S08_RS49330"
                     /old_locus_tag="O0S08_49330"
     CDS             10284..11213
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002629106.1"
                     /locus_tag="O0S08_RS49330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_49330"
                     /product="MvdC/MvdD family ATP grasp protein"
                     /protein_id="WP_269041923.1"
                     /transl_table=11
                     /translation="MLLLSHRQEPFCTARVAGALESRGARALRLDTDDFPEVLQLSAAL
                     DERGARLLLDGEALQVDAVWLWRLWPPRIDARVESGRRQAAQREAATCLRGLLDLLPAA
                     RWIDPIEVVRAAENKPRQLRLARALELAIPPTLITADPAAAAAFFAAHDGQVIAKLQTA
                     LDLSMRGGGGLPTRRLRPEDLPALAGLRHCPMVFQRWVPKALELRIAWVDKRAFVGALD
                     GAQCGVDWRHESTAGWQSYELPAEVHAKLARLMAALGLRQGAIDMIVTPDGAHVFLEVN
                     PHGEWGMLERDLGLPIAAALADALLASE"
     misc_feature    11215..11224
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.02"
                     /tool="antismash"
     gene            11239..12255
                     /locus_tag="O0S08_RS49335"
                     /old_locus_tag="O0S08_49335"
     CDS             11239..12255
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002623136.1"
                     /locus_tag="O0S08_RS49335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_49335"
                     /product="MvdC/MvdD family ATP grasp protein"
                     /protein_id="WP_269036526.1"
                     /transl_table=11
                     /translation="MNRMVMLVTWSGDVSGIVPAMQELLEARGVRALRFDTDAFPTEQQ
                     VRFVHDGATEALQVRDGEVWRTLAPDDAIWYRRARWAGKLPATMDRQLRHGCTVESEAF
                     LRGVMAAAPCFVMDPPEAVRENGHKPYQLSLARRLGLATPRTLATNDPAAAHAFIRACP
                     HGAVAKMLSAFPVYDEQGEEQVVFTTALAEDHLGKLEGLRYAPMVFQERLQKALELRVT
                     VVGRRIFAAAVDSQRQPGAEVDWRERGVSLLRSWVPYDLPAETERRLSEYMERIGMQYS
                     AIDMVVEPDGRHVFLEANPAGECYWLQYNSPHFPLAQALVDVLVDEPGARRASRRVG"
     gene            12313..14040
                     /locus_tag="O0S08_RS49340"
                     /old_locus_tag="O0S08_49340"
     CDS             12313..14040
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012240264.1"
                     /locus_tag="O0S08_RS49340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_49340"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_269036527.1"
                     /transl_table=11
                     /translation="MAWDSSPVIAGLWIAVMGFAAILPLAIAYVGKAIVDAVVERAPGP
                     ALTWVAVELLLMMLVGAAGRGSGVLRGLLGVRLGLHVNLKILRKALTLELLQFQDPEFY
                     DRLTRARREASSRPLALAGELLGVGGSLVTLLGFVALLLSFSPLAVLVLIAAGFPATLA
                     ELRFSREAFDLRHRRTTEARRLGYLEYVLASDEHAKEVMMLGLGPALLARYEAVGERLW
                     REERGLSVRRTLWVTLLAQLGSLAFYGCYALIVWRTAKGELGLGDMTLYVLAFRQGQQL
                     FQAILLGVGSLYEHELYMANLLEFLHREGKPVRPALPMIVTNGVRGIRFEDVGFRYPGQ
                     EGFALRHVDLEMAAGTSIALVGHNGAGKSTFIKLLTGLYEPTEGRVLLDGVDLRQIDRA
                     DLRRRLSVVFQDYNQYQFTAGENVGYGRPEAVADAAAIARAVEDGGARAVIEGLPMGLE
                     TQLGRWFPGGVELSGGQWQRVALARAFMRSEADVVVLDEPTAALDVDAEAELFERVRAS
                     TAGRTLLLISHRLANVRLADWIVVLGPRGVIESGTHAALMAEGGHYAAMFRKQAQGYA"
     gene            14083..14742
                     /locus_tag="O0S08_RS49345"
                     /old_locus_tag="O0S08_49345"
     CDS             14083..14742
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1286: Pentapeptide
                     repeat protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013940315.1"
                     /locus_tag="O0S08_RS49345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_49345"
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="WP_269036528.1"
                     /transl_table=11
                     /translation="MPDLVDLDSLLRDSSFEDQTFNGLEMQEADLAGKEFAGCTFVGCK
                     AQESRWRGARLEDCVFERCDLTQARPAGMIAGKLQFRSCKLMGVEWTELGRFASLSFVE
                     CTLQFASFLRLSLCRAEFVDCTISEANFFEVDLAEANFRGCSLAGSVFRGCKLRKTDFS
                     AATGAFVDPSANEAREAIVPVESAVLLAMHLGLRVAGYSGPAAKSEPTRSGRGRRK"
     misc_feature    complement(14132..14147)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.61"
                     /tool="antismash"
     gene            14919..16043
                     /locus_tag="O0S08_RS49350"
                     /old_locus_tag="O0S08_49350"
     CDS             14919..16043
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS49350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_49350"
                     /product="hypothetical protein"
                     /protein_id="WP_269036529.1"
                     /transl_table=11
                     /translation="MSAIFDPCASSMRRTVGGRWAAGVLIGVALSACASRAASEATTPV
                     PSEPQSAAPVAVEPTPDAPAASVIPADPSEQVDFEPSALAFGRCRSDEADGGPFVVGRD
                     AESWREGEPLWVMTNAGGAVRGAAGKQFEYCGPGLTQPTATGSSEETCVKAVAVVTEGP
                     LRCDESPGNGAARPFTSEPGPQLDYVFAFHRRHRPPTPVRMNFAMRVHAVCQDPAKDFD
                     EPGAMIPVRDGPSPIDKFFEKEIAGLDKRSWRAVRVELEGSNEPLHVLHAAEHQRKAKV
                     AQWSVLREKADGSASELVAKADRSWPDSFLLRDHQCGLPFSPPLPALAFMHGQKLHWVT
                     VEDVNAKAIARVWEVGDQLRRVAVLPVALSSPKW"
     misc_feature    16264..16278
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.37"
                     /tool="antismash"
     misc_feature    complement(16265..16278)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.04"
                     /tool="antismash"
     misc_feature    16266..16280
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.1"
                     /tool="antismash"
     misc_feature    16277..16290
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.55"
                     /tool="antismash"
     misc_feature    complement(16278..16291)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.35"
                     /tool="antismash"
     misc_feature    complement(16279..16292)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.96"
                     /tool="antismash"
     gene            16304..16918
                     /locus_tag="O0S08_RS49355"
                     /old_locus_tag="O0S08_49355"
     CDS             16304..16918
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015246537.1"
                     /locus_tag="O0S08_RS49355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_49355"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_269036530.1"
                     /transl_table=11
                     /translation="MLDVAVIDDPAAATVALDPVRGRLLAELAEPASAANLAARLGIPR
                     QKVNYHLRALEAHALVREAEQRRWGGLTERLFVATASSYVVSPGALGPLAADPARATDR
                     LSAGYLVALAARVVREVGALWRQAVRADKRLATLSMDAEIRFASPRERAAFTEELTRAI
                     TTLAARYHDTSAPGGRDYRLIVMAHPRPAEDARKDRHASQE"
     gene            16902..17720
                     /locus_tag="O0S08_RS49360"
                     /old_locus_tag="O0S08_49360"
     CDS             16902..17720
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020739712.1"
                     /locus_tag="O0S08_RS49360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_49360"
                     /product="SRPBCC domain-containing protein"
                     /protein_id="WP_269036531.1"
                     /transl_table=11
                     /translation="MPVKNDAEKRWVELEFVVPGTPEQLWRAMATGPGIGAWFTTTTVD
                     ERVGGAIEFDFGGGAVSKGVVTRWEPPFRFCYEERGWNGEAPPVATEITIRTRAGEQCV
                     VRMVHSLFTSEDSWDDELEGFESGWPGFFEVLRVYMRQFAGQKASSLRVTSSHAGTPAE
                     AWKSLSAGLGLAGADVGEQREAPSEAPSLAGTVERVQQGGEVFEQMLRLERPGPGVAAI
                     GTYRHAGSARVGVSIYLYGEQAEATAAEAQRRWSAWMAERFPAREAEAKA"
     gene            complement(17744..18385)
                     /locus_tag="O0S08_RS49365"
                     /old_locus_tag="O0S08_49365"
     CDS             complement(17744..18385)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS49365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_49365"
                     /product="hypothetical protein"
                     /protein_id="WP_269036532.1"
                     /transl_table=11
                     /translation="MLAFVAACQPTGPASTDATTGTSTGAPTTTSLDTGAPTTTDGTPT
                     TETPVECMDLSSPFLAADCLVALRNRCLAATDEATCTAREPLLFGDGGYIIRCGWAKVV
                     TFADPATCAVESVVGRCEAGLEDTLLGCGNHCNDENSLQFSLRADVDAAELLEMGCASN
                     GNYLDGPLGARSAVGAEPQEFGTVCIDGVKPPAPPLCDCASAACATEWGE"
     misc_feature    complement(18681..18696)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.28"
                     /tool="antismash"
ORIGIN
        1 gatcgcagga tcgacgcagg tccgcgggct gcggcgcctg atcttgcacg acactgcgat
       61 caccgaggag gaattcgcgg cgctggtgac gacgccgaac ctcgccgggc tgacacactc
      121 gacgctgtcg aacctgtcgc tgccgccggc gcgactggcc cgctggctcg acggtacgcc
      181 gggtcgctcg ctgcgcgagc tggtgctggc aggattcgcg ggcgcggagc atctggaagt
      241 gttgctggcg cgcgcgccgg tgctgctgcg attgcgatcg ctgggcgtcg tcgacgggta
      301 tgtcggtgat gcggaggtgc tccggctggc cgcatgcgag gcgctcggag gtctggcgac
      361 gctcgacttg cgaggttctc gctcgccgat ctcgcaagcc gccgcggcga agttgcgggc
      421 ggccccgcac ctcgcgcgga cgcaggtgtt gctggacgac ggagcgacgg gcagccggta
      481 gcagatcgcg cgaggttcaa gggcgcgact gccctcgaag ggcggcgaac atggccggat
      541 tcgccggtgt tctgtccgaa gggacatgcg ggcctcgtcc agcagagaca gctccgtcgg
      601 cttgccggcg agctgccgcg gcggcgaatc gccgatcgcg tcctgcgcct gtccgaaggg
      661 acattccgag ctcggcccgc agggacggct ccgtcggcga gcttcgtggc ggcgagggcc
      721 gatcctcgat ggaaaaactc aggtagccag aggatcgtga cgatgtcgac gtcgaggccg
      781 atcacggcgg gctcgtcggt gatgcccggg ggcgagctcg gcccgcaggg acggctccgt
      841 cggcgagctt cgtggcggcg agggccgatc ctcggatgga aaaactcagg tagccagagg
      901 atcgtgacga tgtcgtcgtc gaggccgatc acggcgggct cgtcggtgat gcccgggggc
      961 gagctcggcc cgcagggacg gctccgtcgg cgagcttcgt ggcggcgagg gccgatcctc
     1021 ggatggaaaa actcaggtag ccagaggatc gtgacgatgt cgtcgtcgag gccgatcacg
     1081 gcgggctcgt cggtgatgcc cgggggcgag ctcggcccgc agggacggct ccgtcggcga
     1141 gcttcgtggc gacggtggcc aatcttcgga gggggaaaaa ctcagggcag ccagaggatc
     1201 gtgacgatgt cgtcgtcgag gccgatcacg gcggactcgt cggtgatgcc cgggccggtg
     1261 ttggtgaacc aggtcggctc ggcgccggcc cacagctcgg cggtgaacca ccggcggagg
     1321 gcgtcgaggt cgatcatcag gtcggcgagg gcggaggggc ggacggcgtg gagccagccg
     1381 ccctgctcgg cctcggcgcg ctcggcggcc tcctcggcct cgacctcgga gatccgggcg
     1441 cgcgcggtgg cgaggaggcc gtcgacgcac gcctgcatct cggcgcggtc gatcgcgcgc
     1501 cagatgccgt cgacgaaggt gcagtagggg gcgtcctcgg gggtccatcg attgaaatgg
     1561 tcctcgagga aggtctggac gatggtgcgc ttggccgcga cgagcgcgag cggatcggcg
     1621 ccggcctcgg cgagcgcttc gcggtggatc ggctcgagca ccgcgctcgc ggggaccgcc
     1681 ttgagccacg cgctggtcca cgtcgggtac cactggcgct ggatgtgctc ggcgagcgcg
     1741 agccgccgcg cgaggtcggt gtcggggcgc atggaccgaa gggtagcgaa gttcgcgggg
     1801 cccaggatct ggggtgaggc gagagttcgt caaccgccgg gtgcgtcggc cggacgcacc
     1861 ctcgtggccg cgagcccgcg gaggggcggg ccgaggaggc aggcggaatg tgagaactcg
     1921 aggcgccggg gcgtcgctcg cgtaacatcg gcgagcgatg gacgtgcgcg agctgtttcc
     1981 cgagcgggac gagatcgacg aggtgcaggc ggcggcgatt gcggcggtcg ccgcgcggct
     2041 cgggatggag cgcgaatggc tggcggagga cgactacatc cacgagatcg tcggcggggc
     2101 gatcgacggt gagcgggtgg cgtgggtcga gcggcggacg aaggacgacg ggggctgggt
     2161 cgacgtcgac tactccctgc gcatgcgcgt cggtgaggtt ttggtccgtg agtgggtggt
     2221 cgacacgtac aacccgtact tcggctgcga cgtcggctac ctgcgctggt ggggcgaggc
     2281 ggtggtgatc gtctatcgcg agaagcaccg cacgatcgcg tgcaggctgg ggcttgaagg
     2341 tgcgccgcag ctgagggcga tcggggacgg ctggacggcg ctcggcgacg tcctgctgca
     2401 cgagagcgcg gcgcgcgggc tggtcgagcg gctgcagctg ccggagctgc gggcggcgac
     2461 acccatgccg ggggagctgg cgaacgagag gatgtctgtt ggagcatgtt ctcggggaca
     2521 tgtcctcggt gagtcgccgg cggcgctgca gcggcagatc gcggcggggt tgcccgaggt
     2581 cgcggcgccg atcgccgagc tgctggtcgg ggcgctggcg tatcgcttct gggacccgtt
     2641 cccgccgctg gcggcgacct acgaggaggc gttcgacgac caccgctgga acacgccgtg
     2701 ctggttgccg tactacctgg tttgcgcgag cccggaggcg gagcgacagg tgctgctggc
     2761 gcagctcgac gcagtggcgg cgcgaccgcc cgaagcgttc gcagcggagg acaacgccgc
     2821 ggagctggct tgtcgccaca tcgcggggcg ctgcgcagag ctggccgcgg cgtgtcgcgc
     2881 agggcggctg ccgaaagggg agtcttgcta cttctgggtc gattgggcgc aggaggcctt
     2941 cgcgggcgcg gaggcgctgt tcccggcggg gatgtggaag gtgtggcaga cgttgcgccc
     3001 gcgggcgcac gcgctgcagg cgttcggcga gagcaggtga ggctggacca ccggagctgc
     3061 gctggcgcga cgggcgccgg acaatcagcg gatgtccgag cggacatgtc cgaagagact
     3121 tacgccgcgg gcggcgtgag gctcttgcgg ttggccgcga tcgcggcgag cacggccggg
     3181 cggcagccct cgccggcgtg ctcgtcgatg tgcagcagca gcgcgcggcg catgcggggg
     3241 tcccagaagc ggcggatgtg gccggcgatg ccgtcgctga cggcggcggg gtcggggtcg
     3301 gactcgaaga aggtggcgat ttcgttggcc atcctgacca gcttgtgcgc gtccatgatc
     3361 gcctccgtca gtgcgagtcg gtccggggca ggagggcgtc ctgctcctcg ctgaattcgc
     3421 cgaagcggcg ctgccaggtc gaggccggct cgccggtcgg gctgacctgc accgcggtga
     3481 ccttgtactc ggggcagttg gtggcccagt cggagttctc ggtggtgatg acgttggcgc
     3541 ccgagccggg gaagtggaag gtggtgtaga cgacgccggg ctgcatgcgc tcgctgatcg
     3601 tcgcgcgcaa gatggtctcg ccggcgcggc tgacgatctt gcaccaatcg ccttccttga
     3661 tcccgcggtg ctcggcgtcg tgcgggtgga gctcgaggcg gtcctcgtgg tgccaggtgt
     3721 tgttggcggt gcgccgcgtc tgggcgccga cgttgtactg gctgaggatc cgcccggtcg
     3781 tgaggatcag cgggaagcgc cgggtgacgc gctcctgggt ggcgacgtac tcggtgatga
     3841 cgaacttgcc cttgccgcgc acgaactcgt cgatgtgcat gaccggggtg ccctcgggcg
     3901 cccggtcgtt gcacggccac tggatgctgc cgagctggtc gagcttggcg tagctgacgc
     3961 cggtgaaggt cggcgtgagc ctggcgatct cgtccatgat ctgcgacggg tgggtgtact
     4021 gcatcgggta gccgagggcc tcggccagcg cgagcgtggc ctcccagtcg gccttgccgg
     4081 ccagcggcgg cgtcaccttg cggacgcggg agatccgccg ctcggcgttg gtgaaggtgc
     4141 cgtccttctc gaggaacgac gagccgggca agaacacgtg ggcgaacttg gcggtctcgt
     4201 tgatgaagag gtcctgcacg accaggcact cgagcgactc gagcgcggcg gtgacgtgct
     4261 gggtgttggg gtcggactgg gcgatgtcct cgccctggac gtagaggccc ctgaacgagc
     4321 cgtcgatggc ggcgtcgaac atgttgggga tccgcaggcc cggctcggcg tcgatgtcga
     4381 cgccccaggc ggcggcgaac agggcccgca ccgcggggtc gctgacgtgg cggtagccgg
     4441 gcagctcgtg cgggaagctg cccatgtcgc agctgccctg cacgttgttc tggccgcgca
     4501 gcgggttcac gccgacgccc ggccggccga tgttgccggt gaccatggcg aggttggcga
     4561 tgcccatgac catggtcgaa ccctggctgt gctcggtgac gccgaggccg tagtagatgg
     4621 ccgcgttgcc gccggtggcg tagagccgcg cggcggcgcg gatctccgcc gccggcacgc
     4681 cggtgacctc ctcggtggcc tcgggcgcgt tgcgcgggtc gctgatgaag gccttccact
     4741 tgtcgtaggc cggctgctcg cagcgcgtgc gcacgaagtg ctcattgtga agaccctcgg
     4801 tgacgacgac gtgggcgagg gcgttgatga cggcgacgtt ggtgccgggc cgcagctgca
     4861 ggtgatgcgc ggcctcgacg tgggccgagc gcacgaggtc gatgccgcgc gggtcgatga
     4921 cgatgagcct ggcgccggcg cgcaggcgtc gcttcatctg cgaggcgaac acggggtgcg
     4981 cgtcggtggg gttggcgccg atgacgacga tgacgtcggc gtgctcgacg gagtcgaagt
     5041 cctgggtgcc ggccgactcg ccgagagtgg tcttgaggcc gtagccggtg ggcgagtggc
     5101 agacgcgggc gcaggtgtcg acgttgttgt tgccgaaggc ggcgcgcacg agcttctgca
     5161 cgaggtaggt ctcctcgttg gtgcagcgcg aggaggtgat gccgccgacg gcgccgcggc
     5221 cgtacttggc ctggatccgc ttgaactcgc tggcggcgta ggcgatcgcc tcgtcccacg
     5281 agacctcgcg ccacgggtcg cggatcgagc tgcggatcat gggcttggtg atgcggtcct
     5341 tgtgggtggc gtagccccag gcgaaccgac ccttgacgca cgagtggccg tggttggcgt
     5401 ggccgtcctt gttggggacc atgcgcacga cctcgctgcc cttgacctcg gcgcggaagg
     5461 agcaaccgac gccgcagtag gcgcaggtgg tgacgacgct gtggtcgggc tggccgcgct
     5521 cgacgatcga cttctcgacg agggtggcgg tcgggcaggc ctggacgcag gcgccgcacg
     5581 agacgcactc gctgctcttg aagtcggtgt cgccgctggc gatcttcgac tcgaagccgc
     5641 gaccctgcag ggtgagcgcg aaggtgccct ggacctcctc gcaggcgcgg acgcagcgcg
     5701 agcaggcgat gcacttggcc gggtcgaagt cgaagtaggg gttcgaggtg tccttctcgg
     5761 cctgcttgaa atggttggcg ccgtcgaagc cgtaacggac ctcgcgcagg ccgacgacgc
     5821 cggcctgctc ctgcagttcg cagttgccgt tggtcgggca ggtgaggcag tcgagcgggt
     5881 ggtcggagat gtacatctcc atgacgccgc gccgcagctt ggccagcggg tcggactggg
     5941 tccgcacctt catgccgggc tcgacgacgg tggtgcacga ggccggatag ccgcggcgac
     6001 cttcgatctg gaccaggcac aggcgacacg agccgaacgc ctcgagcgac tcggtggcgc
     6061 acagcttggg cacgcgcacg ccggcgtcgg cggccgctcg catcaccgag gtgccggccg
     6121 ggacggtgac ggcgcggccg tcgatctcga gggtgacctg ctcgctgctg ttccgctcgg
     6181 gggtgcccgc gtcgggctct ttgacggagt acatggctga ttcctcctgc ggcgcgtcag
     6241 cgctggaagt cctcggggaa gtgctcgagc gcgctgagca cgggggcggg ggtgaggccg
     6301 cccatggcgc acagcgagcc gtgggtcatg gtgtcgcaga ggtcgcgcaa gagggcgagg
     6361 ttggggccgc ggcgctcgcc cgtgcgaatg cggtcgatga cctcgacgcc gcgggtgctg
     6421 ccgatccggc acggggtgca cttgccgcac gactcgatgg cgcagaactc catggcgtag
     6481 cgggccatga gggccatgtc gacggtgtcg tcgaagacga cgaggccgcc gtggccgatc
     6541 atgccgccgg cggcggcgaa ggcctcgtag tcgagcggga cgtcgaactt cgattcgggc
     6601 aagtaagggc cgagcgggcc gccgacctgg accgcgcgca cgggccgacc gctggcggtg
     6661 ccgccgccgt agtcgtagat gagctcgcgc agggtgaggc cgaaggcctt ctcgaccagg
     6721 ccgccgcgct tgatgttgcc ggccagctgg aacggcaagg tgccgcgcga gcgacccatg
     6781 ccgtagtcgg cgtagtactg cgcgccgcgg tcgaggatga tcgggacgct ggcgagggtg
     6841 atgacgttgt tgatgacggt gggcttgccg aacaggccgg agatcgccgg cagcggcggc
     6901 ttcgggcgca ccatgccgcg cttgccctcg aggctctcga gcatggcggt ttcctcgccg
     6961 cagatgtacg cgccggcgcc gcggcgcagc tcgatgtcga agcggcggcc gctgccgagg
     7021 acgtcgcgcc cgagccagcc ggccgcgcgc gcggcgtcga tcgccgccag caaggtgcgc
     7081 tcggcgtcgg ggtattcgga gcggaggtag atgtagccgt ggtcggcgcc gacggcgaga
     7141 ccggcgatcg tcatgccctc gagcaggagg tacgggtcgc cctccatcaa catgcggtcg
     7201 ctgaaggtgc cgctgtcgcc ctcgtcggcg ttgcagcaga cgtacttctg ctcgcccgcg
     7261 gtgccggcga cggtgcgcca cttgatgccg gccgggaagg cggcgccgcc gcgaccccgc
     7321 aggccgctgc gcacgacctc ctcgaccact tcggcgcctg tccccgcgga cagagcggcc
     7381 cgcagcccgc ggaggccgcc gtgctccttg tagtcggcga ggctcagcgg gtcggtgacg
     7441 ccgacgcggg cgaaggtgag gcgctcctgg ctcttgagcc agtcgaggtc gtcggtgcgg
     7501 ccgtgcgcga gcgggtgagc gccgccgcgc aggaagtcgg cggcgaacag cgaggcgacg
     7561 tcggcgacgt cgaccggccc gtaggcgacg cggccggcgg gggtgacgac ctcgacgagc
     7621 ggctcgagcc agcacaggcc gcgcgtgccg ttgcggacga tctgcaccgg ctcgccgcgg
     7681 gcggcggcct cgcgggcgat cgcggcggcg acgtcgtcgg cgccgacgga ccgcgcggtg
     7741 gcgtcgatcg ggacgtagac gatgtgagtc acgtgcgctc ctccgtgggg gcgacgaggg
     7801 cgtcgaccag gcggtcgagg cgctcgccgg tgaggcggcc gcgcagctga ccgtcgagca
     7861 ggagcgacgg cgcggcggcg cagttgccga ggcagtagac cggctcgagg gtgacggcgc
     7921 cgtcacgcga ggtctcgccg aacttgcacc cgaggcgccg ctcgagcgcg cccgcgaggg
     7981 cctcgctgcc catggcctgg cacgcctcgg cgcggcacag cttgaggacg tggcgccccg
     8041 gcggctggct gcggaagtcg tgatagaagg tgacgacgcc gtggacctcg gcgcgcgaga
     8101 ggttgagggc ggcggcgacg cggccgatgg cctcgggcgg gatgtggccg aggcggtcgg
     8161 cgatgccgtg caggacctgc aacaaaccgc caggcaggtg cccgctctgg gccagcgcct
     8221 ggtcgatcgc gtcggagctc atgctcgcga atctagcgac ttccgggccg agccccaaac
     8281 gcggagtgat cgccgccgcg tcagcgagtg atccggatgc caccgctgta cacggtgaag
     8341 cgaccttcgc gcacgaagcc gagcagggtc atttcggcct cgagggcgag ctcgacggcg
     8401 aggctcgacg gcgcgccgac ggcggcgaag atggggatct gggccatgag ggccttctgg
     8461 accagctcga agctggcgcg ggcgctgacc agcaggacgg cgtcggtcgc gggcagctgg
     8521 ccggcgagca ggagggcgcc gaccagcttg tcgagggcgt tgtgacggcc gacatcctca
     8581 cgcaggagac gaagctcacc acggaggtcg aacaggccgg ccgcgtggat ccctccggtc
     8641 gcggcgaagg tcgcctgcgc tcgcaggagc gcccccggca ggccggggac caccgcggcg
     8701 gccagctggg ggtggcccgg ggtcagcggg cccggggggc gcgcgcgcag gccgtcgagc
     8761 gaggcgcggc cgcacacgcc gcaggcggag gtcatgacga agctgcgctt cgggacagct
     8821 tcgggcaggc gcacgccggc ggcgaggtcg acgcgcacat ggtcttcgga gcaggtgatg
     8881 ccggcgatct gctcgcggcc gcggacgacg ccctcggtga agaggaagcc ggcggcgagg
     8941 tcggcgtcgt cgccgggcgt gcgcatcgtc atcgacagcc ggcgcggctc ggggtcgtcg
     9001 tcggtgacga cgcggatctc cagcggatcc tcgaccgcga gcaggtcgcg gcgcgcgctg
     9061 acgtcgtcgc cgcggtgcag caccgcggcc acggagcgcg tgcgcgggtc gggcgtggtc
     9121 actgcggaag gatgccgaac tcgcggcagg cgggcacgaa gttctcgttc ttgtggctcg
     9181 agcggctcag cttgtagagc gcgaagcgct gcagcggggc cagcgcggcc cactgggccg
     9241 gcgacagcgc gacgccctcg gcggcggcct tggtggcgac gtcgtcgggg acgcgggcgg
     9301 tgtcggccca cggcggggcg gggtcgacgg cgatccgcgc gggcggctcg cccatgcgct
     9361 gctcgaccat ggcgacgacc gcggcgtcga agcggccgac ggggtcggcg tggacggagt
     9421 catcgaggag ggcgacgacg gcgctgcgct gctcggggcc gagcttgacc cactccttga
     9481 gcgagagctt gatcccgcac aggtcgagct ggtgccgcac ggccatggga atgcagcgga
     9541 ggtcggtctg gaagtcgccc tcgaaggcga acagcgcggg gtgatgcggc acgagcggga
     9601 ggctatcgca ggcccgcggg cgacgccagc gaggcgtgcg cggcgcgggg cgggcggcag
     9661 gcgggctcgg cggtgagaac ctgtcctttg gggaatatgt cctcggggac aggtcggcgg
     9721 aggccggcgc cgggcgcctg cgggtggagg cccgccgggg cgcgcgggcg agcggcgaaa
     9781 tttttttcgt cggtggcgcg tgagaggtcg agggcccgct gcttaggtga ccgggcggcg
     9841 cgacgggccc ggtccgatgc gccgccggac gcccgcgggc gtgggcgggc gtccgcgagt
     9901 cacacgcgag gggagggacg acatgctcgc ggggagcacg atggtgtgtc tccacgacgg
     9961 gatgctcgtc tccaggaccc tgtccatcga aaggaaagcc atggcgaaca aacagcccgg
    10021 cgaggcgctg caggcggagg ccttgccgtt cttcgcgcat ctcctgagct cgcagagcga
    10081 ccccgcggcc gacggcggcg gcacgaagcc ggcgcccacc tatcattgcc tcgattcgcc
    10141 ttgcacgaag aagtacccga gcgacgacga cgagtcgacg acctggttca gtgacagcga
    10201 cggctagaga cggaccgcga tcgaagtgac gacccgcgag cgggcgtgag gggcgaggac
    10261 tggcgatgaa acgaggagct caagtgttgc tgctgtcgca tcggcaggag ccgttctgca
    10321 ccgctcgcgt cgcgggcgcg ctcgagagcc gcggcgcgcg ggcgctgcgg ctcgacaccg
    10381 atgattttcc ggaggtgctg cagttgagcg cggcgctcga cgagcgcgga gcgcggctgc
    10441 tgctggacgg ggaggcgttg caagtcgacg cggtgtggct gtggcgcctg tggccgccga
    10501 ggatcgacgc gcgggtggaa tcagggcggc gccaggcggc gcaacgcgag gcggcgacct
    10561 gcctgcgcgg gctgctcgac ctgctgccgg cggcgcggtg gatcgacccg atcgaggtgg
    10621 tccgcgcggc cgagaacaag ccgcggcagc tgcggctggc gcgggcgctg gagctggcga
    10681 tcccgccgac gctgatcacg gccgacccgg cggcggcggc ggcgttcttc gcggcgcacg
    10741 acgggcaggt gatcgccaag ctgcagacgg cgctcgacct ctcgatgcgc ggcggcgggg
    10801 ggctgccgac gcggcggttg cgacccgagg acctgccggc gctggcgggg ctgcgccact
    10861 gcccgatggt gttccagcgc tgggtgccga aggcgctgga gctgcggatc gcgtgggtcg
    10921 acaagcgggc gttcgtcggc gcgctcgacg gagcgcagtg cggggtcgac tggcgccacg
    10981 agtcgacggc cgggtggcag tcgtatgaat tgccggcgga ggtgcacgcg aagctggcgc
    11041 gattgatggc agcgctcggg ctgcggcagg gggcgatcga catgatcgtc acgcccgacg
    11101 gagcgcacgt attcctcgag gtcaaccccc acggcgagtg gggcatgctg gagcgcgacc
    11161 tggggctgcc gatcgcggcg gcgctggcgg acgcgttgct ggcgagtgaa tgagtgattt
    11221 tctaaggagg gcgatcgtat gaatcgaatg gtgatgctgg tgacctggtc gggcgatgtc
    11281 agcgggatcg tcccggcgat gcaggagctg ctggaggccc gcggggtccg ggcgctgcgg
    11341 ttcgacaccg acgcgttccc gaccgagcag caggtgcgat tcgttcatga cggcgcgacc
    11401 gaggcgctgc aggtgcgcga cggcgaggtc tggcggacgc tggcgccgga cgacgcgatc
    11461 tggtaccgcc gcgcgcgctg ggccgggaag ctgccggcga cgatggatag acagctgcgc
    11521 cacggctgca cggtcgagtc ggaggcgttc ctgcgcgggg tgatggcagc ggcgccctgc
    11581 ttcgtgatgg acccgccgga ggcggtgcgg gaaaacggcc acaagccgta tcagctgagc
    11641 ctggcccgcc ggctcgggct cgccacgccg cgcactctgg cgaccaatga cccggcggcg
    11701 gcgcacgcgt tcatccgcgc gtgcccgcac ggggcggtgg cgaagatgct gtcggcgttc
    11761 ccggtgtacg acgagcaggg cgaggagcag gtggtgttca cgacggcgct cgcagaggac
    11821 cacctgggca agctcgaggg cctgcgctac gcgccgatgg ttttccagga gcggctgcag
    11881 aaggcgctcg agctgcgcgt gaccgtggtg ggcagacgga tcttcgcggc cgcggtcgac
    11941 tcgcagcggc agccgggcgc ggaggtcgac tggcgcgagc gcggggtgtc gctgctgcgc
    12001 tcgtgggtgc cgtacgacct gccggccgag accgagcggc gattgagcga atatatggaa
    12061 cgcatcggga tgcagtacag cgcgatcgac atggtggtcg agccggacgg gcgccacgtg
    12121 ttcctcgagg ccaaccccgc gggcgagtgc tactggctgc aatacaacag cccgcacttc
    12181 ccgctggcgc aggcgctggt cgatgtattg gtggacgagc cgggggcgcg acgggctagc
    12241 cggcgggtgg ggtgattcat ggcgcggggc ccgcggagag ctcgccggcg ccagtgggcg
    12301 gaggcgctgc gcatggcgtg ggacagctcg cccgtcatcg cggggctgtg gatcgcggtg
    12361 atgggattcg cggcgatcct gccgctggcg atcgcgtacg tcggcaaggc gatcgtcgac
    12421 gcggtggtcg agcgcgcgcc cggaccggcg ctgacgtggg tggcggtcga gctgctgctg
    12481 atgatgctcg tcggcgcggc cgggcgcggg tcgggggtgc tgcgcgggct gctcggcgtc
    12541 cgcctcggcc tgcacgtgaa cctgaagatc ttgcgcaagg cgctgacgct cgagctgctg
    12601 caattccagg atccagagtt ttacgatcga ttgacgcggg cgcgccgcga ggcgtcgtcg
    12661 cggccgctgg cgctggcggg cgaattgctg ggcgtcggcg ggtcgctggt gacgctgctc
    12721 ggcttcgtcg cgctgctgct cagcttcagc ccgctggcgg tgctggtgct gatcgcggcc
    12781 gggttcccgg cgaccctggc ggagctccgc ttctcgcgcg aggcgttcga cctgcgccat
    12841 cgccggacca cggaggcgcg ccggctcggg tacctcgaat acgtgctggc cagcgacgag
    12901 cacgccaagg aggtgatgat gctcggcctc ggcccggcgc tgctggcccg ttacgaggcg
    12961 gtgggcgagc ggctctggcg agaagagcgc ggcctgtcgg tgcgccgcac gctgtgggtg
    13021 acgctgctgg cgcagctggg gtcgctggcg ttctacggct gctatgcgct gatcgtgtgg
    13081 cgcaccgcga agggggagct cggcctcggc gacatgacgc tctacgtgct ggcgttccgc
    13141 caggggcagc aactgtttca ggcgatcctg ctcggcgtgg gctcgctcta cgagcacgag
    13201 ctgtacatgg cgaacctgct cgagttcctg caccgcgagg ggaagccggt gcggccggcc
    13261 ttgccgatga ttgtgacgaa tggggtgcgc ggcattcgct tcgaagacgt cgggttccgc
    13321 tacccgggcc aggaaggctt cgcgctgcgc cacgtggacc tggagatggc cgccggcacg
    13381 agcatcgccc ttgtcggcca caacggcgcg ggcaagtcga cgttcatcaa attgttgacg
    13441 gggttgtacg agccgaccga ggggcgggtg ctgctcgatg gggtcgactt gcggcagatc
    13501 gatcgcgcag acttgcggcg acggctctcg gtggtgtttc aggactataa tcaataccaa
    13561 ttcacggccg gcgagaacgt cggttacggg cggccggagg cggtcgcgga cgctgcggcg
    13621 atcgcccgcg cggtcgagga cggcggggcg cgggcggtga tcgaggggct gccgatgggg
    13681 ctggagacgc agctcgggcg gtggttcccc ggcggggtcg agctgtcggg cggtcagtgg
    13741 cagcgagtgg cgctggcgcg cgccttcatg cgcagcgagg ccgacgtggt ggtgctcgac
    13801 gagccgactg cggcgctcga cgtcgacgcg gaggcggagc tgttcgagcg ggtgcgggcg
    13861 tcgaccgcgg ggcggacgct gctgctgatc tcgcatcgcc tggccaacgt gcgcctggcc
    13921 gactggatcg tggtgctcgg gccgcgcggg gtgatcgaga gcgggacgca cgcggcgctg
    13981 atggcggagg ggggccatta cgcggcgatg ttccgcaagc aggcgcaggg ctacgcgtag
    14041 cggcttgacc gcggccgacg aagggtgcga gcttgccggc ccatgccgga cctggtcgac
    14101 ctcgacagcc tcctccgcga cagcagcttc gaggaccaga ccttcaacgg gctggagatg
    14161 caggaggccg acctcgcggg caaggagttc gcgggctgca cgttcgtcgg ctgcaaggcg
    14221 caggagagcc gctggcgcgg ggcccggctc gaggattgcg tgttcgagcg ctgcgacctg
    14281 acgcaggcgc ggcccgcagg gatgatcgcg ggcaagctgc agttccgcag ctgcaagctg
    14341 atgggcgtcg aatggacgga gctcggccgc ttcgccagcc tgagcttcgt cgagtgcacg
    14401 ctgcagttcg cgtcgttcct gcggctgagc ctgtgccgcg cggagttcgt cgattgcacg
    14461 atcagcgagg cgaacttctt cgaggtcgat ctcgccgagg cgaacttccg cgggtgctcg
    14521 ctcgccggca gcgtgttccg cggctgcaag ctgcgcaaga ccgacttctc cgcggcgacc
    14581 ggggcgttcg tcgatccctc cgccaacgag gcccgcgagg cgatcgtgcc ggtggagtcg
    14641 gcggtgctgc tggcgatgca cctcgggctg cgcgtggccg gttactcggg gccggcggcg
    14701 aagtcggagc cgacgcggtc cggtcgcggg cggcgtaaat aagcggccct tgcgcgcgcg
    14761 cgagcgcggg aaactctgcg cgtcgaagga ggatggatcg aggcgatcgc cgtcgaagtc
    14821 cgaggccgcg cgagcagacg tcgggcgcgc gtggacaggg cggtggagag ttgataagcc
    14881 tgctgcgacg agcgatgggg cggcgatcag gaattctcgt gagtgcgatc ttcgatccct
    14941 gcgcgtcgtc gatgcggcga accgtcgggg ggaggtgggc ggccggtgtc ctgattggcg
    15001 tcgcgctgtc ggcctgcgcc tcgcgggccg cgtcggaggc gacgacgccg gtgccgtccg
    15061 agccgcagtc cgccgcgccc gtggcggtcg agccgacgcc ggacgcgccg gcggcctccg
    15121 tcatcccggc agatccgtcc gagcaggtcg acttcgagcc gtccgcgctc gccttcggcc
    15181 gctgccgcag cgacgaggcg gacggggggc cgttcgtcgt cggccgcgac gccgagagct
    15241 ggcgcgaggg cgagccgttg tgggtgatga cgaacgccgg cggtgcggtg cggggggccg
    15301 cggggaagca gttcgagtac tgcggcccgg ggctcacgca gccgaccgcg acgggctcgt
    15361 ccgaggagac ctgcgtcaag gcggtggcgg tcgtgaccga ggggccgctg cgctgcgacg
    15421 agtcgcccgg caacggggcg gcgaggccgt tcacgagcga gccggggccg cagctcgact
    15481 acgtgttcgc gtttcatcgc cgccaccgcc cgccgacgcc ggtgcggatg aacttcgcga
    15541 tgcgggtcca cgcggtgtgc caggatcccg cgaaggattt cgacgagccg ggcgcgatga
    15601 tcccggtgag ggacgggccc tcgccgatcg acaaattttt tgagaaagag atcgcggggc
    15661 tcgacaagcg gagctggcgg gcggtgcggg tcgagctcga ggggtcgaac gagccgctgc
    15721 acgtgctgca cgcggccgag catcagcgca aggcgaaggt ggcgcagtgg tcggtgctgc
    15781 gggagaaggc cgacggctcg gcgagcgagc tggtggccaa ggccgatcgc tcgtggcccg
    15841 actcgttcct gctgcgcgac caccagtgcg gcctgccgtt ctcgccgccg ctgccggcgc
    15901 tcgcgttcat gcacgggcag aagctgcact gggtcaccgt cgaggacgtg aacgcgaagg
    15961 ccatcgcgcg cgtgtgggag gtgggcgacc agctgcgccg cgtggccgtg ctgccggtgg
    16021 ccctgtcgtc gccgaagtgg tgagcgggcc gcgggcgaat cgaggtggtg ttagggacat
    16081 gctctttgga gcatgtttgt agagacatgt gcgttctgac agtgacccgg ccgtcgccgg
    16141 agcggtgagc attttaaaga gacgtgacga tcaggacatg tctcttcaag catgcgatcg
    16201 tcgtcgcgga acttggttgc gtgaaacgcg ctgaagtctc atagaatggc gctgcgggcc
    16261 gaaattactt tgacaaattt tttgttcaag ctacggtacg ggcgtgctcg acgtcgccgt
    16321 catcgacgat ccggcggccg cgacggtggc cctcgacccc gtccgcggcc gactgctggc
    16381 cgagctcgcc gagcccgctt cggcggccaa cctggccgcg cggctgggga tcccccggca
    16441 gaaggtcaac taccacctgc gcgccctcga ggcccacgcg ctggtgcgag aggcggagca
    16501 gcggcgctgg ggcgggctca ccgagcggct gttcgtggcg actgcgagct cgtacgtcgt
    16561 ctcaccgggg gcgctggggc ctctcgcggc cgatccggcg cgcgcgacgg atcggctctc
    16621 ggccggctat ctcgtcgccc tcgcggctcg ggtcgtgcgc gaggtgggag ccttgtggcg
    16681 acaggcggtc cgcgccgaca agcggctggc gacgctctcc atggacgccg agatccgctt
    16741 cgcctcgccg cgcgagcgcg cggccttcac cgaggagctc acgcgggcga tcacgacgct
    16801 ggccgcccgc tatcacgata cttcggcgcc gggcgggcgt gactatcgat tgatcgtcat
    16861 ggctcacccc cggcccgcgg aagatgcacg aaaggatcga catgccagtc aagaatgacg
    16921 ccgagaagag atgggtcgag ctcgaattcg tggtgccggg gacgccggag cagctctggc
    16981 gcgcgatggc cacggggccg gggatcggcg cgtggttcac gacgacgacg gtcgacgagc
    17041 gggtcggcgg agcgatcgaa ttcgacttcg gcggcggcgc ggtgtcgaag ggggtggtga
    17101 cgcgctggga gccgccgttc cgcttctgct acgaggagcg cggctggaac ggcgaggcgc
    17161 cgccggtggc cacggagatc acgatccgca cccgcgcggg cgagcagtgc gtggtccgaa
    17221 tggtccacag cctgttcacc agcgaggact cgtgggacga cgagctcgag ggcttcgagt
    17281 ccggctggcc cggcttcttc gaggtgctgc gcgtgtacat gcgccaattc gccggtcaga
    17341 aggcgagctc gctccgcgtg acgagctcgc acgcggggac gccggccgag gcgtggaaga
    17401 gcctgagcgc ggggctcggt ctggcagggg ccgacgtcgg tgagcagcgc gaggccccga
    17461 gcgaggcgcc gagcctcgcc ggcacggtcg agcgcgtgca gcaaggcggc gaggtcttcg
    17521 agcagatgct gcgcctcgag cggcccgggc cgggggtggc ggcgatcggg acgtatcgcc
    17581 acgcgggcag cgctcgcgtc ggggtgagca tttatttgta cggggagcag gcggaggcga
    17641 cggcggccga ggcccagcgg cgctggtcgg cgtggatggc cgagcggttc cccgcgcgcg
    17701 aggccgaggc gaaggcgtag cgacgcctcg tcgcgcacac cgtctattcg ccccactcgg
    17761 tcgcgcaggc cgcggatgca cagtcgcaca gcggcggcgc cggcggcttc acgccgtcga
    17821 tgcacacagt gccgaattcc tgcggctcgg cgccgactgc cgatcgtgcg ccgagggggc
    17881 cgtcgaggta attgccgttg ctcgcacagc ccatctcgag aagctctgcg gcgtccacgt
    17941 ccgcacgcag gctgaactgc aacgaatttt cgtcgttgca gtgattgccg caacccagca
    18001 gggtgtcctc gaggcctgcc tcgcaacgac cgaccaccga ctcgacggcg caggtggccg
    18061 ggtcggcgaa ggtgacgacc ttggcccagc cgcagcggat gatgtatccg ccgtccccga
    18121 acagcaacgg ttcacgcgca gtgcacgtcg cctcgtccgt ggccgccagg cagcggttcc
    18181 tcagcgccac caggcagtcc gccgcgagga agggtgagct gaggtccatg cattccacgg
    18241 gcgtctccgt cgtcggcgtc ccgtcggtgg tcgtcggtgc gccggtgtcg aggctcgtgg
    18301 tcgtgggcgc gccggtgctg gtgccggtgg tcgcgtcggt gctcgccggg cccgtgggct
    18361 ggcacgcggc gacgaatgcg agcacccgga gcgaacgacc gtggagggtg aagcgaccgg
    18421 cttggtcgcg gttcggaggg agtttcgaga tctcttcggt cattgcggtt gcgtgcgagg
    18481 cgacagctgg cgggagcggc ggcggggaag ggctgcgagc atcagcagca gccacgcgga
    18541 tcggccgtcg ccgtcggtcg cgcagccgca gccgtcgtca ccggtcgcgg gggcgccgct
    18601 gtcggtcgcg ccgtcgctcg tgctcggggc ggaggtggag gtggaggtga cgccgtcgct
    18661 cgtgctcgag ccggtcgtcg gtgacgcgcc ggtgtcaccg gtgccgctgt cctcgccggt
    18721 ggtcggggcg cacgcggggt cgccgtcgcc gtcgcagtcg ttgtcgatgc aatcgtcggg
    18781 atcttcgtcc gcgccgggcc agcgggcggg gtcggcgtcg tcgcaatcgc cggcgcacag
    18841 gaggacgccg tcggcgtcgg cgtcgacctc gtcggcgggg atggtctcgt cgcagtcgtt
    18901 gtcgcggccg tcgcagatct cggtcgcgcc ggggtggctg gcagggtcgt cgtcgtcgca
    18961 atcgtcgccg ccgcaggcga ccgcgtagtg cccgtcggcg tcggcgtcga cgcaggtgca
    19021 gtggagcccc gcggcggcga ggccatcgat gaggccccac ccagcgtcgt tgtcgggggc
    19081 gtcgggttgc gtcgcggtgg cgcgcagcag cgcacgcatg ccggccggat cgaggtcggg
    19141 gtaggcctcg agcagcaggg cggcgatgcc ggcggcgagc ggggtcgaga ggctggtgcc
    19201 ctgcgacatc tcgtaggcga cgaggctgtc ggagcgggcc atccacacgt cctggcccgg
    19261 cgccaccagg tcgggcttga tccggtcgtc ggcggtcggg ccgcgcgagg agaagggagt
    19321 gacgacgccg tcgaagtcgg tggcgccgat ggcgatgacg ccgtcgacgt ccgccggcgc
    19381 gtccagggtc ttcggctgcg gcccctggtt gcccatggcg gcgaacatga tgaggccgtt
    19441 ggcgaccgcc acgtttgcgg cctgcgaggc gacggcggtc ttgccgtcga gctgctgggg
    19501 ctcgtaccag tcggagtaac cgagcgaggc ggtgaagatg tcggcgccca tgccctcgat
    19561 ccactcgagg ccggcgacgt agtagtcctc ctcgaagggc tcctcgacgt cgatgcgctc
    19621 ggtcttggcc agaatcaccg cgacgccggg ggcgacgccg gagaagacat cgccgtcgtc
    19681 ggcgacgatc agcgagagga cgccggtgcc gtggtggtgc tgcccggggg tgtcgccctc
    19741 ctggtcggcg acgacgtcgt cgccctgcac gaagtcgcgg gccgcgagca cctgcacctt
    19801 ggagaaggcc tggtgttcga gcaagaagcc ggtgtcctgc acgccgacga ccacgccggc
    19861 gccggtcagg ccgcattcgt gcagctccgg gacgtgcagc gccgagagat gcggccagga
    19921 caggcccttg gcctgcgagg tcggcgattc gtcggtgacg ggcaaggggt gctcatggcg
    19981 ccgcgtccgc gccaccggcc gcgtgcgagt gacgaagggg aggcgagcga tcgcggcccg
    20041 ctgggcggcg tcggcgtcga cgctcactgc attgagccag cgcgaggtgg cacgaatccg
    20101 ggcgccggtg gccgcgaccg attgtacata ggcggacgcg ggcgggaggt cgcggacatc
    20161 gacgccccga tcgccgcgga cccgtgcgcg ccggcgcagg gctcgcg
//
