LOCUS       NZ_CP114040            20996 bp    DNA     circular CON 26-AUG-2024
DEFINITION  Nannocystis poenicansa strain FL3 chromosome, complete genome.
ACCESSION   NZ_CP114040
VERSION     NZ_CP114040.1
KEYWORDS    RefSeq.
SOURCE      Nannocystis poenicansa
  ORGANISM  Nannocystis poenicansa
            Bacteria; Myxococcota; Polyangia; Nannocystales; Nannocystaceae;
            Nannocystis.
REFERENCE   1  (bases 1 to 13228663)
  AUTHORS   Ahearne,A., Stevens,C. and Dowd,S.
  TITLE     Minimal conservation of predation-associated metabolite biosynthetic
            gene clusters underscores biosynthetic potential of Myxococcota
            including descriptions for ten novel species: Archangium lansinium
            sp. nov., Myxococcus landrumus sp. nov., Nannocystis bai
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 13228663)
  AUTHORS   Ahearne,A., Stevens,C. and Dowd,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-NOV-2022) Biomolecular Sciences, University of
            Mississippi, Faser Hall 407, Oxford, MS 38655, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2021
            Assembly Method                   :: IPA v. 10.1.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 250x
            Sequencing Technology             :: PacBio Sequel IIe
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_026965555.1-RS_2024_08_26
            Annotation Date                   :: 08/26/2024 12:45:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,229
            CDSs (total)                      :: 10,129
            Genes (coding)                    :: 10,068
            CDSs (with protein)               :: 10,068
            Genes (RNA)                       :: 100
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 9 of 61
            Pseudo Genes (incomplete)         :: 52 of 61
            Pseudo Genes (internal stop)      :: 2 of 61
            Pseudo Genes (multiple problems)  :: 2 of 61
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:28:22
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 11478787
            Orig. end                         :: 11499783
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP114040.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20996
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="38"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20996
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20996
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10996](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10996)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(461..475)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.14"
                     /tool="antismash"
     misc_feature    complement(466..479)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 17.19"
                     /tool="antismash"
     gene            complement(553..1008)
                     /locus_tag="O0S08_RS44040"
                     /old_locus_tag="O0S08_44040"
     CDS             complement(553..1008)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010396518.1"
                     /locus_tag="O0S08_RS44040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_44040"
                     /product="KGG domain-containing protein"
                     /protein_id="WP_269035511.1"
                     /transl_table=11
                     /translation="MPNSTGNTGERRGGRGFAGMEAEKQREIARKGGRAAHEKGTAHEF
                     DSEEARAAGRKGGEVVSQNREHMAEIGAKGGHASHSNRAAHASASSRDRNRSQRSAQGM
                     TGMSDEPNTPVEDREASTSSAAPENRSEMPRSEPMSPSGRDEGEQDH"
     gene            1375..1638
                     /locus_tag="O0S08_RS44045"
                     /old_locus_tag="O0S08_44045"
     CDS             1375..1638
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS44045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_44045"
                     /product="hypothetical protein"
                     /protein_id="WP_096328304.1"
                     /transl_table=11
                     /translation="MTRNFLVFAVTACLAGLVGFACKSGGGGGSQAPGTVTAIEGPSSC
                     PRSVPTRGASCPRGESEFCVYRTTGGDFACVCGGGKWGCGSK"
     gene            1746..2600
                     /locus_tag="O0S08_RS44050"
                     /old_locus_tag="O0S08_44050"
     CDS             1746..2600
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS44050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_44050"
                     /product="hypothetical protein"
                     /protein_id="WP_269035512.1"
                     /transl_table=11
                     /translation="MLPYLVRARWTAFTLLFACSFDGSGLVSVGPPSSNSSTTGDSTTS
                     TGPGTTVAPTTVESEGSDSDGATMSTTQPVDPTEDPTTTTTTTGTTTTTSTTDPDTTTT
                     STGPDTTTSTSTTSTDTSTSTGPDTTTGPMCMDTGTEPNESEGESVDLGDQHCKAQPKS
                     FEGVLDGDADVDWFRFFGDFSGNQCNDDPIAKIVVTADGPLEVCMYADCDISGETDFDC
                     PNGTSMADSPDGRDGCCGTGSMQYEVNCVSGPDESAAIYVRLQKAPVDACLEYKVDYSY
                     FSP"
     gene            2674..3753
                     /locus_tag="O0S08_RS44055"
                     /old_locus_tag="O0S08_44055"
     CDS             2674..3753
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS44055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_44055"
                     /product="hypothetical protein"
                     /protein_id="WP_269035513.1"
                     /transl_table=11
                     /translation="MPRPHLRRLAALAFFLLACSYDGSGLVSVGEPPSTTTSTGTTTGE
                     PALTTTDAPLTTTGGPDLSTTGTTAPVDPTTDATTTTTTSSTSTTGETSTTTGDETTGP
                     PPPLLIDDGLLVRYFLDEAASGQSPTHALDAAPDPLDLPLVYDGMGGMNPVYVEEAGHR
                     GLRWPMPGLDGRATIAAADTKLQSGLQNRTAATIEIVVEVDAVTDLGSRLTHIGRGIEP
                     GHFTLRSSKIDRLEFYWKGDVLAGVWPVDWNGLGRAVVHVVVDTGQPEPIHRIRLYIDG
                     VVVADGTDIALVPPNQNEAIAIPTDPNIPLHFTLGNRGVDVDRSFQGTLYYAAIYAAAL
                     SETQLAANADILAGLDDAP"
     gene            complement(4254..6494)
                     /locus_tag="O0S08_RS44060"
                     /old_locus_tag="O0S08_44060"
     CDS             complement(4254..6494)
                     /GO_function="GO:0003959 - NADPH dehydrogenase activity
                     [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011565218.1"
                     /locus_tag="O0S08_RS44060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_44060"
                     /product="bifunctional salicylyl-CoA
                     5-hydroxylase/oxidoreductase"
                     /protein_id="WP_269035514.1"
                     /transl_table=11
                     /translation="MKIAVLGGGPAGLYFSVLMKKARPDCEVVVVERNRRRDTFGWGVV
                     FSDGTLGNFRRADPETYAAITEAFIHWDDIDTCIKGQVIRSGGHGFCGIARVRLLEILQ
                     DRALALGVRIEFETEHEGLSSPAVAGADLVVAADGINSKVRTQLGEVFAPTIAEGKAKY
                     IWLGTTKRLSAFTFYVREDEHGLFVVHAYPFDRDTSTFIVETDAETWRRAGLDAMSTDE
                     SVAYCERLFAEELAGHRLMSNKSSWLSFREVKCARWWSGNVVLIGDAAHTAHFSIGSGT
                     KLAMEDSIALCEALLREPTVPAALAAYHEARWLEVAKLQRAAKVSQTWFEEVRRYKDLP
                     PQQFVLSMMTRSKRVTYENLRVRDRDYVGSLDRWFAGENGCESHEPAPPPMFTPLRLRE
                     LTLQNRVVVSPMCQYSAEDGLPNEWHLVHLGGCAVGGAGLVMTEMTDVAPEGRISRGCT
                     GLWSEAHAAAWRRVVDFVHSHSTAKIGVQLGHAGRKGSAAHPWEGADSGLAEGWELLGP
                     SAVPYAPGFAAPKPMTPADMAAVVEQFRRAAKLAEEAGFDLVEVHMAHGYLLASFISPL
                     TNVRSDEYGGSLQNRMRFPLQVLDAVRAEVPAHKPVSVRISATDWIPDGLDEEDAVEIA
                     RLLKAHGCDLVDVSAGQTTPESRPEIYGRMFQTHLSDRIRHEAGVTTMAVGAIQDWDQV
                     NTIIASGRADLCALARPHLLDPHFTLRAAAEQNYRGPGVTWPPQYLPARPRG"
     misc_feature    6594..6607
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.28"
                     /tool="antismash"
     gene            6610..9753
                     /locus_tag="O0S08_RS44065"
                     /old_locus_tag="O0S08_44065"
     CDS             6610..9753
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013713.5"
                     /locus_tag="O0S08_RS44065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_44065"
                     /product="hypothetical protein"
                     /protein_id="WP_269035515.1"
                     /transl_table=11
                     /translation="MSATTGPRDGLLLVAAFASGAAALAYEMLWTRMLALSLGSETVGV
                     LAALAGYFAGLALGAALLHDRTHQARDPVRLFVALELVAAGFAIVSPHLLQLLARVLPA
                     WLGPVAAAGDVTALAASTAVAAAVLALGAAPLGASLAALVEARRRTCPSDQDGRGLGRI
                     YGANTVGAALAAVVSIHLVFPALGYGLGAALAALAGAGAALAARAWGAGTFGHVPQDMS
                     RAPLAPSAVPVLGDMSASGAGLSPAAASPGPADMSAPDAGLSPAAASPGPADISPSDAG
                     PSPAAASPVPADLSASPAAASPVPGDTFSSPDLSLAAASPVPGDTFSSPDLSPAATAPV
                     PGTMSVSPAAPRAPHLAAPAAAVDASRDPDPDLLREPWLLNLVSFGTGLTGIGLQVVGV
                     RVLGQHLENTIYTFAHILAAYLLATGLGAFVYQRLAARAVAGRPGTVTAALLWLLGVMV
                     VPAAVALAHGPELLQALAPEAAGLARAGLAELAVAALVFGPSALVLGALLSHVIGLVAA
                     TGRGVGRTYAYNALGCAAAPFVFGLLAIPRLGYADAFYAVLYAYLALFAVFGWFRRFSP
                     VLLIGGVLAGVALTAAGPRSLVLVGDSDGWVRRDERQTLHGLVAVSERPGPGGAPLRRL
                     QIGKRFRMGGAAGFGEQRMGQVCSLLSHASGPEGPIPKALYLGLGTGSTMGGALAVPHA
                     AAEGVELVPEIVELLPNFADINHDLAKRPEVALHAADARRYLAAAPGSYDLVVADLFHP
                     GQAGASSLFAREHFAAARDHLRPGGLMCQWLPLYQLDEADVRTIVRTFLDVFPESYAFL
                     GIYNAQNPALALVGRVPDPSAAQLRLDVDRLRADTARLQNIVDPRDLLASYVMGPAELS
                     EWSGDGPRNTDLAPEIAFQAARVAYRDDRTLGAHNLAAILGRAVAAPAALLTGGGAEAL
                     AAASGPFTAAARHYLAGEIARGDLADLSNMSWETAEHFVRAYEADPEFAPARGALYTIA
                     RKNQALAAKLLPRMLARTPDEPRVYEAYLQHLRVAGDQAAYQQLRAEAAAKFPGVALP"
     gene            complement(10001..10996)
                     /locus_tag="O0S08_RS44070"
                     /old_locus_tag="O0S08_44070"
     CDS             complement(10001..10996)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.4"
                     /locus_tag="O0S08_RS44070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_44070"
                     /product="hypothetical protein"
                     /protein_id="WP_269035516.1"
                     /sec_met_domain="T1TS (E-value: 4.7e-64, bitscore: 216.6,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSRPEPLAAGVRTQPAGLAIDDFLTLAPRRENPRADEIEARALA
                     LAQELGLVHAGNQARFDAFNSLGRHVYPSATVERGVLCATWCNWLFFFDDMHDEELRSR
                     EDQSRVRRQIDSALALLSGARRPTGEVEPLDRLLLEFRRGALELAGGAWLDRLWCVTAD
                     HMSLGVLPAVRNWGTSRTPPLREYLTQREHDSGVLTALDLIELAAGIAVPPAVRDSPVV
                     LRARRAASRTVGYFNDIVSFPKEVLRHKNPNNLVHVLMCERACSLEAALREATELVNAE
                     ARELDGCVREAAAAHPESPAVQTYLQGLLEWQRGNIEWSLASPRYDATRA"
     misc_feature    11342..11357
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     gene            complement(11343..12479)
                     /locus_tag="O0S08_RS44075"
                     /old_locus_tag="O0S08_44075"
     CDS             complement(11343..12479)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013868.5"
                     /locus_tag="O0S08_RS44075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_44075"
                     /product="STAS domain-containing protein"
                     /protein_id="WP_269035517.1"
                     /transl_table=11
                     /translation="MDERTLLQDAPLVVIEVDPALRVSSWNRRAEQTFKTPQSSALGRG
                     LDELLPLHGTADRWTSLFDDGAESRVWELRGATGKPMLFEAWWQVERDADGSPRGATLY
                     GHDATARITVERRSVLESSMLQAIKEYLDIALWAIDRKGTFLYQDGKGVRTAGMTSHHF
                     VGQNIFDVYADDGDLTGVRRALQGEPISALPAVTHGMHWQTWYIPMQENAADAAVVGIT
                     LDVTEARRSELELRTKLELIERQQEVIRELSTPIIEVWDGVLTLPIVGLVDSVRTAEIM
                     DNLLTSVSRTRARYAILDLTGVEVVDTGTAGHLIGMIQAIRLLGAEGILTGIHPTIAQT
                     IVALGVDLARVAVFAKLRDALKYCIVQMSQRKPTVTAK"
     gene            complement(12579..13670)
                     /locus_tag="O0S08_RS44080"
                     /old_locus_tag="O0S08_44080"
     CDS             complement(12579..13670)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013868.5"
                     /locus_tag="O0S08_RS44080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_44080"
                     /product="STAS domain-containing protein"
                     /protein_id="WP_269035518.1"
                     /transl_table=11
                     /translation="MSEASKLEGAPLIVIEADAGLVVTAWNRRAQLVFGTGAEEAVGRG
                     LAEVLPLAGASWDALLAGDDGEPRVLEVRRADASWTIEVWSQALPAGVRLYAHDVGARV
                     AAQARAALEATMLRAIKENLDVALWATDERGVFLYQDGKVIVDAGIAPHQFVGLSMLEL
                     YKDVGNNPLIERALAGEPARTYAAESHGMYLDTYYIPVAGGPGEPRLIGVTLNVTEAKR
                     VENEMRSKLELIERQQEVIRVLATPIIEVWDGVLTMPIVGLIDTARTAEIMDSLLEAVT
                     QTRARFAILDLTGVEVVDTGTASHLIRMIRAIKLLGAEGILTGIHPTIAQTIVGLGVDL
                     THVAVYAKLRDALKHCLRAARKA"
     gene            13855..14718
                     /locus_tag="O0S08_RS44085"
                     /old_locus_tag="O0S08_44085"
     CDS             13855..14718
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS44085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_44085"
                     /product="hypothetical protein"
                     /protein_id="WP_269035519.1"
                     /transl_table=11
                     /translation="MPRVRPQIGLVIALLGPPQPAHADVLLNPKGKRAVEVTIAIENLD
                     AHPEYLFVLWPGGCLRNDETFAKYTVLSSQEDDGRNDFSEDGCVAQRLFAFPRDTYSVT
                     DDVLAENGRRQLSNDPPSDPRVLVRPIKAEALWWVPFEVDLYGIEDVYRVGIDAGALTL
                     TPTRVRFDHGSGRILDRAFNKKGQRPRIPRPEDIPPAPPPEPVAAAPAVADGTPPEAKA
                     EPAPIAAEAPAPIAPAPASAPTPPPPAAKPREEISAGPWPPPPLMYGGACLLVAVAAGL
                     ALRRRK"
     misc_feature    13933..13935
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(14814..16016)
                     /locus_tag="O0S08_RS44090"
                     /old_locus_tag="O0S08_44090"
     CDS             complement(14814..16016)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014845.5"
                     /locus_tag="O0S08_RS44090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_44090"
                     /product="V4R domain-containing protein"
                     /protein_id="WP_269035520.1"
                     /transl_table=11
                     /translation="MVSEISSSIAERLVLRYDAPSGRRVIAGKDVLLHCHHYNARLQRT
                     VESADLVDGKRLLVGAAECVFAEHIDLALRAGDSLEVRWAVAERLYSHLGFGRLDLSRA
                     AEGVIEASASHFVEGWFAGLGRPERMVCSFAEGYVQGAAYAVTGELVYVREVECMAQGA
                     PKCRFVVERGRSEPVARNAKRPLAFRPRERGDWLRSPAIDEQAIIDALVAMPVEGGPDG
                     LIPAFGVYLACMPADFYNRVCIGFLAEMRRVGRGPTAERLLAAEAEYCALNTYRGVMSS
                     PEWDGLVAPMLRGPDDPLFAAMTFCNALGFGRWHIAGLEPGQWMIVESVNGYEAIGARE
                     YLGATSTPHCNGHKGAAAGIFALIYGDGPLSERFGTFHTVEETCIACGDPVCRFRVERL
                     G"
     gene            16096..16824
                     /gene="mddA"
                     /locus_tag="O0S08_RS44095"
                     /old_locus_tag="O0S08_44095"
     CDS             16096..16824
                     /EC_number="2.1.1.334"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="mddA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003936334.1"
                     /locus_tag="O0S08_RS44095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_44095"
                     /product="methanethiol S-methyltransferase"
                     /protein_id="WP_269035521.1"
                     /transl_table=11
                     /translation="MGRFIVLVHGVVAYIVVLAVFTYFAGFVADVGVPRAIDDGPVGPW
                     PRALAIDLALVAGFALQHSVMARPWFKRIWTVFIHESAERSTYVLLASLQLALMMWAWQ
                     PLPSPIWQLGDGVLAGLVQFVAALGWGLVLVSTFAVDHFHLFGLRQAVCHWLGGPAYEP
                     EFRVRGPYRLVRHPIMLGFLIAFWAAPTMSVGHLGFALAMTAYVLVALELEERDLRAQH
                     GAHYHGYAAQIPRLNPFARR"
     gene            16879..18519
                     /locus_tag="O0S08_RS44100"
                     /old_locus_tag="O0S08_44100"
     CDS             16879..18519
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (19-440). E-value: 7.5e-87.
                     Score: 283.5. Matches aSDomain:
                     nrpspksdomains_O0S08_RS44100_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017332004.1"
                     /locus_tag="O0S08_RS44100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_44100"
                     /product="3-(methylthio)propionyl-CoA ligase"
                     /protein_id="WP_269035522.1"
                     /sec_met_domain="AMP-binding (E-value: 9.8e-93, bitscore:
                     310.1, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHLTGLMMHSPLLISGLIRHAARVHADQTMVSRTVEGPIHRTTYR
                     ALERRARQLAEALQALGVGPGDRVATLAWNGFRHVETYFAVSGVGAVCHTLNPRLFPEQ
                     LVYILNHAEDGVLLTDLTFVPLVEKLAPRCPNLRAVVVMTDREHMPQTTLPNVHVYEDI
                     LAAQPGALEWPEFAEDTASSLCYTSGTTGEPKGVLYSHRSTVLHSFGIALPDVFRLGER
                     ETVLPVVPMFHVNAWGLPYAAALTGTRLVLPGPRLDGESLYSLFEDEGVTMSAGVPTVW
                     MGLLAHMKQQGKRFSALKRVVIGGSAAPEAMIRSFQDDYGVEVLHAWGMTETSPLGTAC
                     GLSPAIRTWPKDQQIAVQRKQGRQVFGVELRIVGDDGTPLVHDGAAAGDLQIRGPWVCS
                     AYYKAESTAHHDGWFSTGDVATIDPAGYMQITDRSKDVIKSGGEWISSIALENLAVGVP
                     GVAEAAVIGVAHPRWAERPLLVLVKQPGAEVDPEIVLAHIAESVPRWWLPDAVEFVDAL
                     PHTATGKISKLQLRERFKDYRLAEDCAQR"
     aSDomain        16936..18198
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_O0S08_RS44100_AMP-binding.1"
                     /evalue="7.50E-87"
                     /label="O0S08_RS44100_AMP-binding.1"
                     /locus_tag="O0S08_RS44100"
                     /protein_end="440"
                     /protein_start="19"
                     /score="283.5"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="HAARVHADQTMVSRTVEGPIHRTTYRALERRARQLAEALQALGVG
                     PGDRVATLAWNGFRHVETYFAVSGVGAVCHTLNPRLFPEQLVYILNHAEDGVLLTDLTF
                     VPLVEKLAPRCPNLRAVVVMTDREHMPQTTLPNVHVYEDILAAQPGALEWPEFAEDTAS
                     SLCYTSGTTGEPKGVLYSHRSTVLHSFGIALPDVFRLGERETVLPVVPMFHVNAWGLPY
                     AAALTGTRLVLPGPRLDGESLYSLFEDEGVTMSAGVPTVWMGLLAHMKQQGKRFSALKR
                     VVIGGSAAPEAMIRSFQDDYGVEVLHAWGMTETSPLGTACGLSPAIRTWPKDQQIAVQR
                     KQGRQVFGVELRIVGDDGTPLVHDGAAAGDLQIRGPWVCSAYYKAESTAHHDGWFSTGD
                     VATIDPAGYMQITDRSKDVIKS"
     CDS_motif       17428..17481
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_O0S08_RS44100_0001"
                     /evalue="4.90E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="O0S08_RS44100"
                     /protein_end="201"
                     /protein_start="183"
                     /score="22.2"
                     /tool="antismash"
                     /translation="LCYTSGTTGEPKGVLYSH"
     gene            complement(18631..19065)
                     /locus_tag="O0S08_RS44105"
                     /old_locus_tag="O0S08_44105"
     CDS             complement(18631..19065)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012238057.1"
                     /locus_tag="O0S08_RS44105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_44105"
                     /product="DoxX family protein"
                     /protein_id="WP_269035523.1"
                     /transl_table=11
                     /translation="MSRLLPTIARVLLGLTFLVFGLNGFLNFMPTPPVPARAGEFLGAL
                     AASGYMFPLIKGTEVFAGALLLSGRLVPFALVLLAPVIVHIVAFHLALAPGGYGLLAFI
                     VGLEAYLAWAYRDSFAPVLNPNARPVAGEHAALRLARARA"
     gene            19131..20051
                     /locus_tag="O0S08_RS44110"
                     /old_locus_tag="O0S08_44110"
     CDS             19131..20051
                     /GO_function="GO:0001216 - DNA-binding transcription
                     activator activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1031: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013206916.1"
                     /locus_tag="O0S08_RS44110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_44110"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_269035524.1"
                     /transl_table=11
                     /translation="MTTIDPVKVAAFVRVVEAESFTAAAQQLGLPKSSVSRSVARLEED
                     LGVRLLQRTTRRLNLTDAGSAFYQKARGALSALEEAALTAADLGHEPRGTVRITAPVDL
                     GEFLAEPLTRFVREHPQIQIDLVLTARLVDMVREGFDLALRASRLKDSSLIARKLGSFA
                     DGLYAAPSYLKRHGPPATLAELVHHECVLFRARGGRSTWTLRGPKGEEQVEVAGAINVD
                     DLSFVVFAAEAGAGIAYLPHMLAARSVAAKRLVRVLPDHCWTHADLSLVLPTGRHVPTR
                     VALLRDFLAESLKTTFGAHRNMKSA"
     misc_feature    complement(19157..19166)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     misc_feature    19281..19283
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 ctgccagccc agggtcgcct cgatctccgt cgtcgtgctg cggcgctggg ccatgccgca
       61 tggtccccgg cccgtgtcca cgccgcaagg aggtcccgcc tgcgggcgca tccgcgagct
      121 cccctcgccc gcgccggtca cgacccccgc agctccgatc gggcacgacg gagatcgcct
      181 cgctctcgcg cgcgcgcgat ccgggacgct cacaagctcc gatcggacac gacggagatc
      241 gcctcgctcc tgcaatcgcg tgaacaatcg ggcccgatgg agctcatcgc gcgctcacgg
      301 gctctcgcat ccgccagggc ccgaccggga gatcgccaca ttcctggact cgcgcgaatc
      361 gacaaaaatg ccatcactcg cgaggcggaa gagatcccct gcgctctcga gctctcctcg
      421 ctgtgacaat cccgcgaatc ggccaatgcg atcgcaatcg atcgataaga aaaattaaac
      481 gacaagtgcg ggcggccgta cgaggcggcc gcccgcgagt cgcgggcgag ggcccgcgac
      541 tcggaactcg ggtcaatgat cctgttcgcc ctcgtcgcgg ccgctggggg acatcggctc
      601 gctgcggggc atctcggacc tgttctcggg ggcggccgac gaggtcgacg cctcgcggtc
      661 ttcgacgggg gtgttcggct cgtccgacat gcccgtcatg ccctgggcgc tgcgctggga
      721 gcggttgcgg tcgcggctgc tcgcgctcgc atgggcggcg cggttgctgt gcgacgcgtg
      781 gccgcccttt gccccgatct ccgccatgtg ctcgcggttc tggctgacca cctcaccgcc
      841 cttgcggccg gcggcacgcg cctcttccga gtcgaactcg tgggccgtgc ccttctcgtg
      901 cgcagcccgg ccgcccttcc gcgcgatctc ccgctgcttc tccgcctcca tccccgcgaa
      961 accgcggccc ccgcggcgtt cccctgtatt accggtgctg ttcggcattg ctggtacctc
     1021 tgtcgcggac tgaaatccgc gccgtgatgg gttctttgaa tggatgtcct cgaggccaga
     1081 gcgcagacag cgctgcccaa ggacgtttcg tgggaaccat ggtcgactgc gtcacctcgg
     1141 caaggcggag ctcggcgcgc ctggggggta gccgccccca attcgtttgg cgatcccgcc
     1201 gccggggccg ctgggacggg tgccgcgccg ctgaggccgc tgggggcctc cgggataccc
     1261 tgagtcacat gcgcctgcga cgaccgcaat tttcactcag cgcagcgcgc gatagtgcgc
     1321 gctggccgcg atggcgttga caccgcactc tgccgggggg acgctggggt cacgatgacc
     1381 cgcaatttcc tcgtcttcgc cgtcaccgcg tgcctcgccg gattggtcgg attcgcctgc
     1441 aagagcggcg gcggaggtgg ttcacaggcg cccgggacgg tcaccgcgat cgaaggtccg
     1501 tcgtcgtgtc cgcggtcggt gccgacgcgg ggcgcctcct gtccgcgggg cgagtccgag
     1561 ttttgcgtct accgcaccac cggcggcgat ttcgcgtgcg tgtgcggcgg cggcaagtgg
     1621 ggttgcggct ccaaatagag agatacggcg atctgcgaac ggctcgccgc gcctgcgtcg
     1681 gccgaggggg ttcgtcgcgc ccgccccgct ggctcgccgg cgcgcgcctg cgataccctc
     1741 cgacgatgct tccttatctc gttcgcgccc gctggaccgc gttcactctg ctcttcgcct
     1801 gcagcttcga cggcagcggc ctggtgagcg tggggccgcc gagctcgaac agcagcacga
     1861 ccggcgactc gaccacctcg acgggccccg ggacgaccgt cgcgccgacg accgtcgagt
     1921 cggagggcag cgacagcgac ggcgcgacga tgagcaccac ccagccggtc gacccgacgg
     1981 aggacccgac gacgaccacg accacgaccg gcaccaccac cacgacgagc accaccgacc
     2041 cggacacgac gacgacctcg acgggtcccg acaccaccac ctcgaccagc accaccagca
     2101 ccgataccag cacctcgacc ggccccgaca ccaccaccgg gccgatgtgc atggacaccg
     2161 gcaccgagcc gaacgagagc gagggcgaat cggtcgacct cggcgatcag cactgcaagg
     2221 cccagccgaa gagcttcgag ggcgtcctcg acggcgacgc cgacgtcgac tggttccgct
     2281 tcttcggcga cttcagcggc aaccagtgca acgacgaccc gatcgccaag atcgtcgtca
     2341 ccgccgacgg cccgctcgag gtgtgcatgt acgccgactg tgacatctcc ggtgaaaccg
     2401 acttcgactg ccccaacggc acctcgatgg ccgactcgcc cgacggccgc gatggctgct
     2461 gcggcaccgg cagcatgcag tacgaggtca attgcgtgtc cggccccgac gagagcgcgg
     2521 cgatctacgt ccgcctgcaa aaggcccccg tcgacgcctg tctcgaatac aaggtcgact
     2581 acagctattt cagcccgtga cgcctggcgc ccccgcccga gcgcgcaggc gcgtgtgctt
     2641 cgcggctgag accgctgcgg tagcctcggg ccgatgccgc gtccgcacct ccgccgtctc
     2701 gccgcactcg cgttcttcct cctcgcgtgc agctacgacg gcagcggcct cgtgagcgtc
     2761 ggggagccgc cgtcaaccac gacctccacc ggcacgacca ccggcgagcc cgcgctcacc
     2821 accaccgacg cgccgctcac caccaccggc gggcccgacc tctcgacgac aggcaccacc
     2881 gcgcccgtcg atccgaccac cgacgcgacg acgacgacca ccacgtcctc gacgtccacc
     2941 accggcgaga cctcgaccac caccggcgac gagaccaccg gtccgccgcc gccgctgctg
     3001 atcgacgacg gcctgttggt ccgctacttc ctcgacgagg cggcaagcgg ccagagcccc
     3061 acccacgccc tcgacgcggc gcccgacccg ctcgacctgc cgctcgtcta cgacggcatg
     3121 ggcggcatga acccggtgta cgtcgaggag gccggccacc gcggcctgcg ctggccgatg
     3181 ccggggctcg acggccgggc cacgatcgca gccgccgaca ccaagctcca gtccggcctg
     3241 cagaaccgca ccgccgccac catcgagatc gtcgtcgagg tcgacgcggt caccgacctc
     3301 ggctcgcgcc tgacgcacat cggccgcggc atcgaacccg gccacttcac cctgcgctcg
     3361 agcaagatcg atcgcctcga gttctactgg aagggcgacg tcctcgccgg cgtgtggccg
     3421 gtcgactgga acgggctcgg ccgcgccgtc gtccacgtcg tcgtcgacac cggccagccc
     3481 gagccgatcc accgcatccg cctctatatc gacggcgtgg tggtcgccga cggcacggac
     3541 atcgcgctcg tccctcccaa ccagaacgag gcgatcgcga tccccaccga ccccaacatc
     3601 cccctgcatt ttaccctggg caaccgcggg gtcgacgtcg accgctcgtt ccagggcacc
     3661 ctctattacg cggcgatcta cgccgccgcc ctgtcggaga cccagctcgc ggcgaacgcc
     3721 gacatcctcg ccggcctcga cgacgcgccg taaatccgtg agcgagagcg cttcgggcca
     3781 ggccgcatga acctgtcccc agggacatcc tccctacgac cgcgctctgt cgctcgcatc
     3841 gcgcccggcg atcgcggggt cgaagcaaca ccggcggtcc tcgacggcgc gccgtgacct
     3901 cccaggtcgg atgaacctgg ccccagagac atctcccgtg cggccggctc tgtcgctcgc
     3961 atcgtacccg gcgatcgcgg ggtcgaagca accacgccgg tcctcgacgg cgcgctgtga
     4021 ccacccgggt atagaaccaa aggacatgtc gcatcgacca tgtctatgga cacatgggcc
     4081 gctcagcccc gacctggccg gctctgccgc tcccgacgac cgccgcggag gccgggtcgg
     4141 ggccgccgag cgctgcggct ccgtgcgacg tcatgccgcg agccgagcgc tgttcgccgt
     4201 cattccgcgc cgggggcggt tgccgcgacg cgcatcgacg cggccgcgcc gggtcagccg
     4261 cgcgggcggg ccggcaggta ctgcggcggc caggtcacgc cgggcccgcg gtagttctgc
     4321 tcggcggccg cgcgcagcgt gaagtgcggg tcgagcaggt gcggccgggc cagcgcgcac
     4381 aggtcggcgc ggcccgaggc gatgatggtg ttgacctgat cccagtcctg gatcgcgccg
     4441 accgccatgg tcgtcacccc ggcctcgtgg cggatccggt cgctcaggtg ggtctggaac
     4501 atgcggccgt agatctccgg ccgcgactcc ggcgtcgtct gcccggccga gacatcgacc
     4561 aggtcgcagc cgtgggcctt gaggaggcgc gcgatctcga ctgcgtcctc ctcgtcgagg
     4621 ccgtcgggga tccagtcggt cgcggagatc cgcaccgaca ccggcttgtg cgccggcacc
     4681 tccgcgcgca ccgcgtcgag cacctgcagc gggaagcgca tgcgattttg cagcgagccc
     4741 ccgtactcgt cgctgcgcac attggtcagc ggcgagatga acgacgccag caggtagccg
     4801 tgggccatgt ggacctcgac cagatcgaaa cctgcctctt cggccagctt ggccgcgcgc
     4861 cggaattgct cgaccaccgc cgccatgtcc gccggcgtca tcggcttcgg cgccgcgaag
     4921 ccgggcgcgt agggcacggc cgacggtccg agcaattccc agccctcggc cagcccgctg
     4981 tctgcgccct cccacgggtg cgcggccgag cccttgcggc cggcgtggcc gagctgcact
     5041 ccgatcttcg ccgtggaatg cgaatgcacg aagtcgacca cccggcgcca cgcggccgcg
     5101 tgggcctccg accacagacc agtgcagccg cgggagatcc gcccctccgg ggccacatcg
     5161 gtcatttcgg tcatcaccag gcccgcgccg ccgacggcgc agccgcccag gtgcaccagg
     5221 tgccattcgt tgggcagccc gtcctccgcc gaatactggc acatcggcga caccaccacc
     5281 cggttctgca gcgtcagctc gcgcaggcgc agcggcgtga acatcggcgg cggcgccggc
     5341 tcgtgcgatt cgcagccgtt ctcgccggcg aaccagcggt cgaggctgcc gacgtagtcg
     5401 cggtcgcgga cgcgcaggtt ctcgtaggtc acccgcttgg agcgggtcat catgctgagg
     5461 acgaactgct gcggcggcag gtccttgtag cggcggacct cctcgaacca cgtctggctg
     5521 accttggcgg cgcgctgcag cttggcgacc tcgagccagc gggcctcgtg gtaggcggcc
     5581 agggccgcgg ggaccgtcgg ctcgcggagc agcgcctcgc acagggcgat cgagtcctcc
     5641 atcgccagct tggtgccgga gccgatcgag aagtgggcgg tgtgggcggc gtcgccgatg
     5701 agcaccacgt tgccggacca ccagcgggcg cacttgacct cgcggaacga cagccagctc
     5761 gacttgttgc tcatcaggcg gtggcccgcc agctcctcgg cgaacaggcg ctcgcagtag
     5821 gccacgctct cgtcggtgct catcgcgtcg agcccggcgc ggcgccacgt ctcggcgtcg
     5881 gtctcgacga tgaacgtgct ggtgtcgcgg tcgaacgggt aggcgtggac gacgaacagc
     5941 ccgtgctcgt cctcgcggac gtagaacgtg aacgccgaca gccgcttggt cgtgccgagc
     6001 cagatgtact tcgccttgcc ctcggcgatc gtcggcgcga acacctcgcc cagctgcgtc
     6061 cggaccttgc tgttgatccc gtcggccgcc accaccaggt cggcgcccgc gaccgccggc
     6121 gagctcagcc cctcgtgctc cgtctcgaac tcgatccgca ctcccagcgc cagcgcccgg
     6181 tcttgcaaga tctcgagcag gcgcacccgc gcgatcccgc agaacccgtg gccgccggaa
     6241 cgaatcacct gtcccttgat acaggtgtcg atatcgtccc agtgaatgaa cgcctcggtg
     6301 atcgccgcgt acgtctccgg gtcggcgcgg cggaagttgc cgagagtgcc gtcggagaac
     6361 accacgcccc agccgaacgt gtctctgcgc cggttgcgct cgacgaccac gacctcgcag
     6421 tcgggccgcg ctttcttcat gagcacgctg aaatacaggc cagcagggcc gccgccgagg
     6481 accgcgatct tcaccgcgca atgctaaccc gccgctcgac ggccgcccaa gtgagaagcc
     6541 tcgcggtggt gcgagcgatc gtcttcgggc tcgcgccgaa tggggggccg ccgtgtatgc
     6601 tcacgcggca tgtcagcaac gaccggcccg cgcgacggcc tcctgctggt cgccgcgttc
     6661 gcctcgggcg cggcggccct cgcctacgag atgctgtgga cgcgcatgtt ggcgctgtct
     6721 ctcggcagcg agaccgtcgg cgtgctcgcg gccctggccg gctacttcgc cggattggcc
     6781 ctcggggccg cgctgctgca cgatcgcacc caccaggccc gcgaccccgt gcgcctgttc
     6841 gtcgcgctcg agctggtcgc cgccggcttc gcgatcgtct cgccgcacct cttgcagctg
     6901 ctcgcccgcg tgttgccggc ctggctcggc ccggtcgccg cggccggtga cgtcaccgcc
     6961 ctggccgcct cgaccgccgt cgccgccgcc gtcctcgctc tcggcgctgc cccgctcggc
     7021 gcctcgctcg ccgccctcgt ggaggcccgc cgccgcacct gtccttcgga ccaggacggc
     7081 cgcggcctgg ggcggatcta cggcgccaac accgtcggcg ctgccctcgc cgccgtcgtc
     7141 agcatccacc tggtgttccc cgccctcggc tacggcctcg gcgccgccct cgccgccctc
     7201 gccggagccg gcgccgccct ggccgcccgc gcctggggcg ccggcacttt tggacatgtc
     7261 ccccaggaca tgtcccgggc gcccctcgcg cccagcgctg ttcctgtcct cggggacatg
     7321 tccgcctcgg gcgccggcct ctcgcccgcc gccgcatcgc ctggccctgc ggacatgtcc
     7381 gccccggacg ccggcctctc gcccgccgcc gcatcgcctg gccctgcgga catatccccc
     7441 tcggacgccg gcccctcgcc cgccgccgca tcgcctgtcc ctgcggacct gtccgcctcg
     7501 cccgccgcgg cctcgcctgt cccaggggac acgttctcgt cgcccgacct ctcgctcgcc
     7561 gcggcctcgc ctgtcccagg ggacacgttc tcgtcgcccg acctctcgcc cgccgcgacc
     7621 gcgcctgtcc ccgggaccat gtccgtgtcg cccgctgcgc ccagggcccc ccatctcgcc
     7681 gcccccgcgg cggcggtcga cgcctcgcgc gaccccgacc ccgacctgct gcgcgagccg
     7741 tggctgctga acctcgtgtc cttcgggaca ggtctgaccg gcatcggcct ccaggtcgtc
     7801 ggcgtacggg tcctcggcca gcacctcgag aacaccatct acaccttcgc ccacatcctc
     7861 gccgcctacc tgctcgccac cggcctcggc gccttcgtct accagcgcct cgccgcgcgg
     7921 gcggtcgccg ggcggccggg gactgtgacc gcggcgctgt tgtggctgct cggcgtgatg
     7981 gtcgtcccgg cggcagtcgc cctcgcccac gggcccgagc tgctgcaggc gcttgcgccc
     8041 gaggccgcag gtctcgcgcg cgccggcctg gccgagctgg cggtcgcggc cctcgtgttc
     8101 ggcccctcgg ccctggtgct cggcgccctg ctcagccacg tcatcggcct ggtggcagcc
     8161 accggccgcg gcgtcggccg gacctacgcc tacaacgccc tcggctgcgc cgccgccccg
     8221 ttcgtgttcg gcctcctcgc cattccccgg ctcggctacg ccgacgcctt ctacgccgtg
     8281 ctctacgcct acctggccct gttcgcggtg ttcgggtggt tccgccggtt ctcgccggtc
     8341 ctgctgatcg gcggcgtcct ggccggcgtc gccctcaccg ccgcgggccc gcgctcgctg
     8401 gtcctcgtcg gcgacagcga cggctgggtc cgccgcgacg agcgccagac cctgcacggc
     8461 ctcgtcgccg tcagcgagcg ccccggcccc ggcggcgccc cgctgcgccg gctgcagatc
     8521 ggcaagcggt tccgcatggg cggcgccgcc ggcttcggcg agcagcgcat gggccaggtc
     8581 tgctcgctcc tgtcccatgc atcaggtccc gaaggaccta tcccaaaggc cctgtacctc
     8641 gggctaggta ccggctcgac catgggcggc gcgctggccg tcccgcacgc cgcggccgag
     8701 ggcgtcgagc tggtgccgga gatcgtcgag ctcctgccca acttcgccga catcaaccac
     8761 gacctggcca agcgccccga ggtcgcgctg cacgccgccg acgcccgccg ctacctcgcg
     8821 gccgcgccgg gcagctacga cctcgtggtc gccgacctgt tccaccccgg ccaggccggc
     8881 gccagcagcc tgttcgcccg cgagcacttc gccgcggccc gggaccacct gcgccccggc
     8941 ggcctgatgt gccagtggct gccgctctac cagctcgacg aggccgacgt gcgcacgatc
     9001 gtccgcacct tcctcgacgt gttccccgag tcgtacgcgt tcctcggcat ctacaacgcc
     9061 cagaaccccg cgctcgccct cgtcggccgc gtgcccgatc cgtcggcggc gcagctccgg
     9121 ctcgacgtcg atcgcctgcg agcggacacc gccaggctgc agaacatcgt cgacccgcgc
     9181 gacctgctgg cctcctacgt catgggcccg gccgagctgt ccgagtggtc cggcgacggc
     9241 ccgcgcaaca ccgacctggc gcccgagatc gcgttccagg ccgcccgcgt cgcctaccgc
     9301 gacgaccgca ccctcggcgc ccacaacctc gcggcgatcc tcgggcgcgc ggtcgcggcc
     9361 ccggccgccc tgctcaccgg cggcggcgcc gaggccctcg cggccgccag cgggccgttc
     9421 accgccgccg cgcgccacta cctggccggc gagatcgccc gcggcgatct ggcagatctt
     9481 tcaaacatgt cctgggagac agccgagcac ttcgtccgcg cctacgaggc cgaccccgag
     9541 ttcgcgcccg cccgcggcgc cctctacacc atcgcccgca agaaccaggc gctggccgcg
     9601 aagctgctcc cgcgcatgct ggcccgcacg cccgacgaac cgcgcgtcta cgaggcgtac
     9661 ctccagcacc tccgggtcgc cggcgaccag gccgcctatc agcaattgcg cgccgaggcg
     9721 gccgccaagt tccccggcgt cgcgctgccg tgagcacgag cccgagccgc ttcgccctcg
     9781 cggagccccg gacctccagg ccaatcgaag cgtcctgacg cggcgaccgc ggccgggccg
     9841 ttcgaactcc ggccgtcctc cgggcggtcg cccgggttcc tttggctgtc cctcgggaca
     9901 gccaccccgg gaccagccgc acgtccgcct caccgcttgg ctgtccttcg agacagccga
     9961 gtcgcgcggg tgatttttta aggtgtcctg cgggacaggc tcacgcccgc gtcgcgtcgt
    10021 agcgcgggct ggccagcgac cactcgatgt tgccgcgctg ccactcgagc agcccctgca
    10081 ggtacgtctg caccgcgggg ctctcgggat gggccgcggc cgcctcgcgc acgcagccgt
    10141 ccagctcgcg ggcctcggcg ttgaccagct cggtcgcctc gcgcagggcc gcctcgagcg
    10201 agcaggcgcg ctcgcacatc agcacgtgga ccaggttgtt ggggttcttg tggcgcagga
    10261 cctctttggg gaacgacacg atgtcgttga agtagccgac ggtgcggctg gccgcgcggc
    10321 gggctcgcag caccaccggg ctgtcgcgca ccgccggagg gacggcgatc ccggcagcca
    10381 gctcgatcag gtcgagcgcc gtgagcaccc cgctgtcgtg ctcgcgctgc gtcaggtact
    10441 cgcgcagcgg cggcgtgcgc gacgtgcccc agttgcgcac cgccggcagc acgccgagcg
    10501 acatgtgatc ggcggtcacg caccacaggc gatcgagcca ggccccgccg gccagctcga
    10561 gcgccccgcg gcggaactcg agcagcaggc gatcgagcgg ttcgacctcg ccggtcggcc
    10621 ggcgcgcgcc cgacagcagc gccagcgcgc tgtcgatctg ccgccgcacc cggctctggt
    10681 cctcgcggct gcgcagctcc tcgtcgtgca tgtcgtcgaa gaagaacagc cagttgcacc
    10741 acgtcgcaca cagcaccccg cgctcgaccg tggccgacgg atagacgtgg cgcccgagcg
    10801 agttgaaggc gtcgaagcgg gcctggttgc cggcgtggac caggccgagc tcctgcgcca
    10861 gcgccagcgc gcgggcctcg atctcgtccg cgcgcgggtt ctcgcgccgc ggcgccaggg
    10921 tcaggaagtc gtcgatcgca agaccggccg gctgcgtgcg cacgccggcg gccagcggtt
    10981 cgggtcgaga ggtcacaaag agagtggtcg tcgcgtccga tacgggcgag agggtcgtca
    11041 tggggggtca ggtcttgttg tccgagggtc gcagggccgg caaccacgcg agctatggct
    11101 cgccgcgccg ggggcggggt ggcgcgcacc atgagcgacg cgggacgccc gaatggatct
    11161 cggccatttg tcgccgaatt cgggggcctg tcgcctgatg cgcgtcaagc gcagagaatt
    11221 ctcgcagccc gcgctcgtgg cggcggatcc gcgtcgacgc cggctgcgcg ccggcgtccg
    11281 tgggattgct tcggtgcatg gtcaatgaac agaggacgcg cggatcgggg gtcgcgagcc
    11341 tgtcacttgg ccgtcactgt cggcttgcgc tggctcatct gcacgatgca gtacttgagc
    11401 gcgtcgcgga gcttggcgaa caccgccacc cgggcgaggt cgacgccgag ggcgacgatc
    11461 gtctgggcga tggtcggatg gatgcccgtc aggatgccct cggcgccgag caggcggatc
    11521 gcctggatca tgccgatgag gtggcccgcg gtgccggtgt cgacgacctc gacgccggtg
    11581 aggtcgagga tcgcgtagcg ggcccgcgtc ctcgacaccg acgtcagcag gttgtccatg
    11641 atctcggcgg tacggacgct gtcgaccagg ccgacgatcg gcagcgtcag cacgccgtcc
    11701 cacacctcga tgatcggcgt cgagagctcg cggatcacct cctgctggcg ctcgatcagc
    11761 tcgagcttgg tgcgcagctc gagctcgctg cggcgcgcct cggtgacgtc gagcgtgatg
    11821 ccgaccaccg ccgcgtcggc ggcgttctcc tgcatcggga tgtaccacgt ctgccagtgc
    11881 atcccgtgcg tcacggccgg cagcgccgag atcggctcgc cctgcagcgc ccggcgcacg
    11941 ccggtgaggt cgccgtcgtc ggcgtagacg tcgaagatgt tctggcccac gaaatggtgc
    12001 gacgtcatcc cggccgtgcg cacgcccttg ccgtcctggt agaggaacgt gcccttgcga
    12061 tcgatcgccc acagggcgat gtcgaggtac tccttgatcg cctgcagcat cgacgactcg
    12121 agcaccgagc ggcgctcgac cgtgatgcgg gccgtcgcgt cgtggccgta gagcgtcgcc
    12181 ccgcgcggcg agccgtcggc gtcgcgctcg acctgccacc acgcctcgaa cagcatcggc
    12241 ttgccggtcg cgccgcgcag ctcccatacg cgcgattctg cgccgtcgtc gaacagcgac
    12301 gtccatctgt ccgctgtccc gtgcagcggc aacagctcgt cgagcccgcg tccgagcgcc
    12361 gagctctggg gggtcttgaa ggtctgttcc gcccgccgat tccagctgga cacgcgcagc
    12421 gccgggtcga cttcgatgac cacgaggggc gcgtcctgca gcaaggtccg ttcgtccacg
    12481 catcctttgt accgtgtccg cggacagctg tccgcatctg ctcgtgcgga ccttgcgtgc
    12541 gtcttcgcgc ggcctccggg ccggcgcgag atcgccgatc aagccttgcg agcggcgcgg
    12601 aggcagtgtt tgagggcgtc gcgcagcttg gcgtacacgg cgacgtgggt cagatcgacg
    12661 ccgagcccga cgatggtctg cgcgatcgtc gggtggatgc cggtgaggat cccttccgcc
    12721 ccgagcagct tgatcgcgcg gatcatccgg atcaggtggc tcgcggtgcc ggtgtcgacg
    12781 acctcgacgc cggtgaggtc gaggatcgcg aagcgggccc gcgtctgcgt gactgcctcg
    12841 agcaggctgt ccatgatctc ggcggtgcgg gcggtgtcga tgagcccgac gatcggcatc
    12901 gtcagcacgc cgtcccacac ctcgatgatc ggcgtggcga gcacacggat cacctcctgc
    12961 tggcgctcga tcagctcgag cttgctgcgc atctcgttct cgacccgctt ggcctcggtg
    13021 acgttgagcg tgacgccgat cagccgcggc tcgcccggcc cgccggccac cgggatgtaa
    13081 tacgtgtcga ggtacatccc gtggctctcg gccgcgtacg tgcgcgccgg ctcgcccgcc
    13141 agcgcccgct cgatcagcgg gttgttgccg acgtccttgt acagctcgag catgctgagg
    13201 ccgacgaact ggtgcggcgc gatgccggcg tcgacgatca ccttgccgtc ctggtagagg
    13261 aacaccccgc gctcgtcggt cgcccacagc gcgacgtcga ggttctcctt gatcgcccgc
    13321 agcatcgtcg cctcgagcgc cgcccgggcc tgcgcggcca cgcgagcgcc gacgtcgtgg
    13381 gcgtagaggc gcacgccggc cggcagcgcc tgcgaccaga cctcgatcgt ccagctcgcg
    13441 tcggcgcggc ggacctcgag cacccgcggc tccccgtcgt ccccggcgag cagcgcgtcc
    13501 cagctcgcgc cggcgagcgg cagcacctcg gccaggccgc ggcccacggc ctcctctgca
    13561 cctgtcccga agaccagctg ggcgcggcgg ttccaggcgg tgaccacgag cccggcgtcg
    13621 gcctcgatca cgatcagggg ggcgccctcc aacttgctgg cttcgctcac ggacccctgt
    13681 ttatcgcaac gcgaggccga ctgtccgcac cccccgtggc gaaacgccga cgcgcggccg
    13741 cgccctgctc gtgagctgtc tcttcgacca tgtcgttcgg cgccccccgc taaaagtgcg
    13801 aaggctccgc cgctgaccca ccacgcggcc ggcagatcca ctaaaacatt cgacatgcct
    13861 cgcgttcgac cgcagatcgg gctcgtgatc gcgctcctcg gcccgcctca gccggcccac
    13921 gccgacgtgc tcttaaaccc gaagggcaag cgcgccgtcg aggtcacgat tgcgatcgag
    13981 aacctcgacg cgcacccgga gtacctgttc gtgctgtggc ccggcggctg cctgcgcaac
    14041 gacgagacct tcgccaagta cacggtgctg tcctcgcagg aggacgacgg ccgcaacgac
    14101 ttctccgagg atggctgcgt cgcccagcgc ctgttcgcgt tcccgcgcga cacctactcg
    14161 gtcaccgacg acgtcctcgc cgagaacggc cgccgccagc tgagcaacga cccgcccagc
    14221 gacccacgcg tgctggtgcg gccgatcaag gccgaagcgc tgtggtgggt gcccttcgag
    14281 gtcgacctct acggcatcga ggacgtgtac cgcgtcggca tcgacgccgg cgccctgacg
    14341 ctcaccccga cccgcgtccg gttcgaccac ggcagcggac gaatcctcga ccgcgccttc
    14401 aataaaaagg ggcaacgccc gcggatcccc cggccggagg acatcccgcc ggccccgccg
    14461 cccgaacctg tcgcggccgc tcccgcggtc gccgacggga cgcccccgga ggcgaaggcc
    14521 gaacccgccc cgatcgccgc cgaggccccc gcaccgattg caccggcgcc ggcgtcggca
    14581 ccgactccgc cgcccccggc cgcgaaacct cgcgaggaga tctcggccgg cccgtggccg
    14641 ccgccgccgc tgatgtacgg cggcgcgtgc ctgctggtgg cggtcgccgc cggcctcgcg
    14701 ctgcggcgcc gcaagtagcc ggcgaggctc gacgaggcgc tccgagcgga tgatcccaag
    14761 gacatgtccc attcgacatg tctttaaaaa acatccaggg acgctccgcc gcctcagccg
    14821 aggcgttcga cgcggaagcg gcacaccggg tcgccgcagg cgatgcacgt ctcctcgacc
    14881 gtgtggaacg tgccgaaccg ctcgctcagc gggccgtcgc cgtagatgag ggcgaagatc
    14941 ccggcggcgg cgcccttgtg gccgttgcag tgcggcgtgc tcgtcgcgcc gaggtactcg
    15001 cgggcgccga tcgcctcgta gccgttgacc gactcgacga tcatccactg gcccggctcg
    15061 agcccggcga tgtgccaccg accgaagccg agcgcgttgc aaaaggtcat cgccgcgaac
    15121 agcggatcgt cgggcccgcg cagcatcggc gccaccaggc cgtcccactc cggcgagctc
    15181 atcaccccgc gatacgtgtt gagcgcgcaa tactcggcct cggccgccaa tagtcgctcg
    15241 gccgtcgggc cgcggccgac ccgccgcatc tccgccagga agccgataca cacgcgattg
    15301 taaaaatcgg ccggcatgca cgcgaggtac acgccgaagg cggggatcag gccgtcgggg
    15361 ccgccctcga ccggcatcgc caccagcgcg tcgatgatcg cctgctcgtc gatcgccggc
    15421 gagcgcaacc agtcgccgcg ctcgcgcgga cggaacgcca gcggccgctt ggcgttgcgc
    15481 gcgaccggct ccgaccgccc gcgctcgacc acgaagcgac acttcggcgc gccctgggcc
    15541 atgcactcga cctcgcgcac gtacaccagc tcgcccgtga ccgcgtacgc ggccccctgc
    15601 acgtagccct cggcgaagct gcagaccatc cgctcgggcc gcccgagccc ggcgaaccat
    15661 ccctcgacga agtgcgacgc cgaggcctcg atgacgccct cggcggcgcg cgacaggtcg
    15721 aggcggccga agccgaggtg cgaatagagg cgctcggcca cggcccagcg cacctcgagg
    15781 ctgtccccgg cgcgcagcgc caggtcgatg tgctcggcga atacacactc cgcggcgccg
    15841 acgagcaggc gcttgccgtc gacgaggtcg gccgactcca cggtccgctg cagccgcgcg
    15901 ttgtagtgat ggcagtgcag gagcacgtcc ttgccggcga tcacccgccg accgctcggc
    15961 gcgtcgtagc gaagcaccag ccgctccgcg atcgaagaag agatctccga aaccatgggg
    16021 cctccgcggc gcattgtgcc acgtatgacc catcaccgcc ccctgtcgac gcgcgcccac
    16081 ccttaccatg acgtcatggg ccgcttcatc gtcctcgtcc acggcgtcgt cgcctacatc
    16141 gtcgtcctcg ccgtgttcac ctacttcgcc ggcttcgtcg ccgacgtcgg cgtgcccagg
    16201 gcgatcgacg acggacccgt gggcccgtgg ccgcgcgcgc tggcgatcga cctggcgctc
    16261 gtcgccggct tcgcgctgca gcacagcgtg atggccagac catggttcaa gcgcatatgg
    16321 acagtgttca tccacgaatc cgccgagcgc tcgacgtacg tcctgctggc gtcgctgcag
    16381 ctcgcgctga tgatgtgggc ctggcagccg ctgccctcgc cgatctggca gctcggcgac
    16441 ggcgtcctcg cgggcctcgt gcaattcgtg gccgcgctcg gttgggggct cgtgttggtg
    16501 tccacgttcg ccgtcgatca cttccacctg ttcggcctgc gccaggcggt ctgccactgg
    16561 ctcggtggcc cggcgtacga gccggagttc cgcgtccgtg gtccctatcg cctggtccgt
    16621 cacccgatca tgctggggtt tctgatcgcc ttctgggccg cgccgacgat gagcgtcggc
    16681 cacctcggct tcgcgctggc gatgaccgcc tacgtcctcg tcgcgctcga gctcgaggag
    16741 cgcgacctcc gcgcccagca cggggcgcac taccacggct acgcggccca gatcccccgc
    16801 ctgaacccgt tcgcgcgccg ctgacccact tgcgccgcgc gcacgcgttg gcccaaactc
    16861 gccggcctgg agcctcgcat gcacctcacc ggcttgatga tgcactcacc tctgctgatc
    16921 tccgggctca tccgccacgc cgcgcgggtg cacgccgacc agaccatggt gtcgcgcacc
    16981 gtcgagggcc cgattcatcg caccacctat cgcgcgctcg agcggcgcgc ccgccagctc
    17041 gcggaggcgc tgcaggccct cggcgtcggc cccggcgacc gcgtcgccac cctggcgtgg
    17101 aacggcttcc gccacgtcga gacctacttc gcggtgtccg gcgtcggcgc ggtgtgccac
    17161 accctcaacc cgcgcctgtt ccccgagcag ctggtctaca tcctcaacca cgccgaggac
    17221 ggggtcctgc tgaccgacct gaccttcgtg ccgctggtcg agaagctggc cccgcgctgc
    17281 cccaacctgc gcgcggtggt cgtcatgacc gaccgcgagc acatgcccca aacgacattg
    17341 ccgaacgtac atgtctacga ggacatcctc gcggcccagc cgggcgcgct cgagtggccc
    17401 gagttcgccg aggacaccgc ctcgtcgctg tgctacacca gcggcaccac cggtgagccc
    17461 aagggcgtgc tctacagcca ccggtcgacg gtgctgcact cgttcgggat cgccctgccc
    17521 gacgtgttcc ggctcggcga gcgcgagacg gtgctgccgg tggtgccgat gttccacgtc
    17581 aacgcctggg gcctgccgta cgcggccgcg ctgaccggca cgcgcctggt cctgcccggc
    17641 ccgcggctcg acggcgagag cctctattcg ctgttcgagg acgagggcgt gaccatgagc
    17701 gccggcgtgc cgacagtgtg gatgggcctg ctcgcgcaca tgaagcagca gggcaagcgc
    17761 ttcagcgcct tgaagcgcgt cgtcatcggc gggtcggcgg cgccggaggc gatgatccgc
    17821 agcttccagg acgactacgg cgtcgaggtc ctgcacgcct ggggcatgac cgagaccagc
    17881 ccgctgggga ccgcctgcgg cctgagcccg gcgatccgca cctggcccaa ggaccagcag
    17941 atcgcggtgc agcgcaagca gggccggcag gtgttcgggg tcgagctgcg gatcgtcggc
    18001 gacgacggca cgccgctggt gcacgacggc gcggccgcgg gcgacctgca gatccgcggc
    18061 ccctgggtgt gcagcgccta ttacaaggca gagtcgaccg cgcatcacga cggctggttc
    18121 agcaccggag acgtcgccac catcgatccg gccggctaca tgcagatcac cgaccgctcg
    18181 aaggacgtca tcaagtccgg cggcgagtgg atctcctcga tcgcgctcga gaacctcgcg
    18241 gtcggcgtgc cgggcgtcgc cgaggcggcg gtgatcggcg tggcccaccc gcgctgggcc
    18301 gagcggccgc tgctcgtcct ggtcaagcag cccggggccg aggtcgatcc cgagatcgtg
    18361 ctcgcgcaca tcgccgagag cgtgccccgg tggtggttgc cggacgccgt cgaattcgtc
    18421 gacgccctgc cgcacaccgc caccggcaag atctccaagc tgcaattgcg cgagcggttc
    18481 aaggactaca ggctcgccga agactgcgcg cagcgctgac gcctcgatcg ggcgtcgcgc
    18541 gggccgggcc gcgccgtgac gggggcatca gcccgagtac ccccctcggg cggcgcgtcg
    18601 gggcccgcgc gacgcacggt cgcggggcgc tcacgcgcgg gcccgggcca gccgcagcgc
    18661 ggcgtgctcg ccggcgaccg ggcgcgcgtt cgggttcagc accggggcga agctgtcgcg
    18721 gtaggcccac gcgaggtacg cctcgaggcc gacgatgaac gccagcaggc cgtaaccgcc
    18781 tggcgcgagg gccaggtgga aggcgacgat gtggacgatc accggcgcga ggaggaccag
    18841 cgcgaacggc accaggcggc ccgacagcag cagcgcgccg gcgaacacct ccgtgccctt
    18901 gatcagcggg aacatgtaac cgctggcggc cagcgccccg aggaactcac cggcgcgggc
    18961 cggcaccggc ggggtcggca tgaagttcag gaagccgttg agcccgaaca ccaggaaagt
    19021 gaggccgagg aggacgcgcg cgatggtggg aagcaagcgg gacatgcggc gagcttaggg
    19081 cttgcggcgg ggccgaccag gtgggatagt cacaactcat cgttgctccc atgacaacaa
    19141 tcgatcctgt caaggtggcc gccttcgtgc gcgtggtcga ggcggagagc ttcaccgccg
    19201 ccgcccagca gctgggcctg cccaagtcgt cggtcagccg cagcgtcgcg cgcctcgagg
    19261 aggacctcgg ggtgcggctc ttacagcgta ccacgcgacg cctgaacctc acggacgccg
    19321 gcagcgcctt ctatcaaaag gcgcgcgggg ccctgtcggc gctcgaggag gccgcgctga
    19381 ccgccgccga cctcgggcac gagccgcgcg gcaccgtgcg catcaccgcg ccggtcgacc
    19441 tcggcgagtt cctggccgag ccgctgacgc ggttcgtgcg cgagcacccg cagatccaga
    19501 tcgacctggt gctgactgcg cggctggtcg acatggtgcg cgagggcttc gacctggccc
    19561 ttcgggcatc tcgcctcaaa gactcgagcc tgatcgcgcg caagctcggc agcttcgccg
    19621 acggcctgta cgccgcgccg tcgtacctca agcgccacgg cccgccggcg accctggccg
    19681 agctggtcca ccacgagtgc gtgctgttcc gcgcccgcgg cggccgcagc acctggaccc
    19741 tgcgcgggcc caagggcgag gagcaggtcg aggtcgccgg ggcgatcaac gtcgacgacc
    19801 tgtccttcgt cgtcttcgcc gccgaggccg gggccggcat cgcctacctg ccccacatgc
    19861 tcgcggcccg ctcggtggcc gccaagcgcc tcgtgcgagt cctgcccgac cactgctgga
    19921 cccacgccga cctctcgctg gtcctgccca ccggccgcca cgtcccgacc cgcgtggccc
    19981 tgctgcgcga cttcctcgcc gagtcgctca agacgacctt cggcgcgcac cgcaacatga
    20041 agtcggcgtg acgcagcgac tgcgatgatt ggcgggtgat cgccgcgcgc aattcgaccg
    20101 cgcggaatcg acggactcgc agaatcgccc ggggcggcct cgcgccccgg cgggcgcccg
    20161 gccgtgttat cgtggctgca tggtatcggt cgggtatggg tggggtcggc ggctcgtcgc
    20221 ggtcgcgcga ttgtcttgtg tctccgtatg catcgtcgcc acggcgctcg agccgctggc
    20281 cgtcgccgcg cccgcgcgcc cgaacatggc ggcggtcgac gccggtatgc gccgcgggca
    20341 ggacgaatac aaccgcggcg agtacagcgc ggccgcgcac gcgtggatcg acgccgccga
    20401 gctgatgccg gagaccccgg agcaccggga caaccgggcg gcgatctacg aatacgcggc
    20461 cgacgcgttc gtgaaggcga tcgaggcccg cggcgaggcg gtcgtcgccg ccgaactggt
    20521 caccgtattg agcgcgctcg acaaatacgc agaggcacac gcgacggcat atcccgggca
    20581 gagcttgccg tccaccgtgg tcaaggcgca ggtgtacgtc cgcggcaagc tggccgcgct
    20641 cgacaaggcc cggcggccgg cgcccgagtc gccgcagccg ctcccggagc cggagcgctc
    20701 gaagccagcc ccgcccgcgc cgagcaagcc gtggaagggc ctggcgatcg gcggcggcgt
    20761 ggccctcggg gccggcgtga cgatggcggt gctcttcggc gccagcctgg tgcagatgaa
    20821 ccgctacgag gacgggttca accacccgaa ccacgcctgc gacccgaacg cgctggaggg
    20881 catctgcgcc gattatcatc gccgcgcgac caacctcgat cgcgccgcca ccatcggcat
    20941 catctccgcg ccggtgttcc tggctgccgg cgcgacgctg ctggcgctcg gcctgc
//
