LOCUS       NZ_CP114040            21497 bp    DNA     circular CON 26-AUG-2024
DEFINITION  Nannocystis poenicansa strain FL3 chromosome, complete genome.
ACCESSION   NZ_CP114040
VERSION     NZ_CP114040.1
KEYWORDS    RefSeq.
SOURCE      Nannocystis poenicansa
  ORGANISM  Nannocystis poenicansa
            Bacteria; Myxococcota; Polyangia; Nannocystales; Nannocystaceae;
            Nannocystis.
REFERENCE   1  (bases 1 to 13228663)
  AUTHORS   Ahearne,A., Stevens,C. and Dowd,S.
  TITLE     Minimal conservation of predation-associated metabolite biosynthetic
            gene clusters underscores biosynthetic potential of Myxococcota
            including descriptions for ten novel species: Archangium lansinium
            sp. nov., Myxococcus landrumus sp. nov., Nannocystis bai
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 13228663)
  AUTHORS   Ahearne,A., Stevens,C. and Dowd,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-NOV-2022) Biomolecular Sciences, University of
            Mississippi, Faser Hall 407, Oxford, MS 38655, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2021
            Assembly Method                   :: IPA v. 10.1.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 250x
            Sequencing Technology             :: PacBio Sequel IIe
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_026965555.1-RS_2024_08_26
            Annotation Date                   :: 08/26/2024 12:45:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,229
            CDSs (total)                      :: 10,129
            Genes (coding)                    :: 10,068
            CDSs (with protein)               :: 10,068
            Genes (RNA)                       :: 100
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 9 of 61
            Pseudo Genes (incomplete)         :: 52 of 61
            Pseudo Genes (internal stop)      :: 2 of 61
            Pseudo Genes (multiple problems)  :: 2 of 61
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:28:22
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 9679207
            Orig. end                         :: 9700704
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP114040.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21497
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="32"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21497
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21497
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11497](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11497
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    793..811
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 21.43"
                     /tool="antismash"
     gene            complement(929..1207)
                     /locus_tag="O0S08_RS36975"
                     /old_locus_tag="O0S08_36975"
     CDS             complement(929..1207)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1132: DNA-binding
                     protein HU 1"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004511650.1"
                     /locus_tag="O0S08_RS36975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_36975"
                     /product="integration host factor subunit alpha"
                     /protein_id="WP_269034172.1"
                     /transl_table=11
                     /translation="MTKADIIERVSDELGGLSKKEAVDMVEIVLELIKETLASGESVKL
                     PGFGNFVVRYKTTRRGRNPKTGEEMMLEARRVLTFKPSNRLKATINA"
     misc_feature    complement(1173..1188)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.78"
                     /tool="antismash"
     misc_feature    complement(1376..1385)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.45"
                     /tool="antismash"
     gene            complement(1617..2663)
                     /locus_tag="O0S08_RS36980"
                     /old_locus_tag="O0S08_36980"
     CDS             complement(1617..2663)
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012298.5"
                     /locus_tag="O0S08_RS36980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_36980"
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_269034173.1"
                     /sec_met_domain="Pkinase (E-value: 9.5e-49, bitscore:
                     165.3, seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 7.2e-06, bitscore: 25.3,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNAASLNPTPGASPATWIGHTLDGRYRLRELIGEGGMGAVFTAE
                     QLSLRTMVAVKMIHAEFTGNAEISERFRREAMATAKIDHPNVVRAIDFGPLPGGGAYLV
                     TQLVRGRTLTNTIASGKLPWRKACDIGAQIADALVAAHGAGIIHRDLKPDNILLEARED
                     ATVVKVLDFGLARVADSGPDMTPLTRLGTVMGTPGYMSPEQAAGEPTDHRTDMYALGVI
                     LWESLAGRELWDGGELSDITIRQLTQAPPALAREIPDLPPELDRLLSQLLAREAAQRPQ
                     TAREVRDQLRALANRPASAVVAPTPPPQPPASQPQRPAPPPNRGLMVFITVFAALALLI
                     IALWAMGQ"
     gene            complement(2947..3225)
                     /locus_tag="O0S08_RS51415"
     CDS             complement(2947..3225)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020512.5"
                     /locus_tag="O0S08_RS51415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF1918 domain-containing protein"
                     /protein_id="WP_371879512.1"
                     /transl_table=11
                     /translation="MPSRRAPPHGPGWPRLTGPGPQRKNARKEFIMQAHVGDSIRITVL
                     SDPPLVGEIVEVLGPDGAPPYRVKFPNGHELVMNPSPDTIIEHKRPR"
     gene            3623..5173
                     /locus_tag="O0S08_RS36985"
                     /old_locus_tag="O0S08_36985"
     CDS             3623..5173
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012298.5"
                     /locus_tag="O0S08_RS36985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_36985"
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_269034174.1"
                     /sec_met_domain="Pkinase (E-value: 5.1e-45, bitscore:
                     153.0, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNAPESTPRESRWIGRVVDERYKIVEVLGEGGMGAVFVAEHLRL
                     RKQVAFKTIRAEFAAHTQAEARFEREALATGRLDHPHVASAIDYGPLPEGGFYLVTQLV
                     RGESLSKRLEAGPLPWPQVCLLGSQIADALAAAHALGIVHRDLKPDNILLEQRRDGALH
                     VRVVDFGIARVSGEQATIADVAQPLTRLGAVIGTPGYMSPEQGTGQQVDFRADLYALGV
                     ILWESFTGQQLWQGDTLVQMLTRQLGRPAPSLRADVPEAMAVMIERLLARAPAERPESA
                     LEVRDELRRLVFGNEVSLPPAVSASAALSSAMSGSAARPLVATPGEVTHADVRSGTTAA
                     TKPSGVLEPGTSPRKSPRGVWIGMAGALVIVLAVLVYGRSKTDEITSETAVGTESAPVD
                     TKPTPHATVDELIAQAPAAYAEDVKMLLISRHPQARRLASEAIAGAPSRDLKKIPEYLR
                     DFARLELADDCDDKKAILKKFEAAEEVRALPGLKAIAGGRSDSCELRDELTRLIARFE"
     misc_feature    complement(5239..5254)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.31"
                     /tool="antismash"
     misc_feature    complement(5435..5451)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.57"
                     /tool="antismash"
     gene            5570..6070
                     /locus_tag="O0S08_RS36990"
                     /old_locus_tag="O0S08_36990"
     CDS             5570..6070
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS36990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_36990"
                     /product="hypothetical protein"
                     /protein_id="WP_269034175.1"
                     /transl_table=11
                     /translation="MPKFDFVSAIEDRKRQLLVEELRKQHELTIGELNQLARGELGPVL
                     RSITIAELMGSGPVPGVSGAARGASPRPEARVPRRNPSNSSSSQNKPLRNEVVTRTAAG
                     REAFDKQILEVIEAIGGPASATEIQRRVGGTNMQVRSGVNRLIEAGHVTWTGKARGTRY
                     YPA"
     gene            6684..7001
                     /locus_tag="O0S08_RS36995"
                     /old_locus_tag="O0S08_36995"
     CDS             6684..7001
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS36995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_36995"
                     /product="hypothetical protein"
                     /protein_id="WP_269034176.1"
                     /transl_table=11
                     /translation="MDRALKLGFDGFNAASSANIPEQSEPGEAAGLMVVNGKVDQGSSA
                     NKGMRLEVSLADYSDGLIEGVYDVVYDGGPNGIFRRKAGTIHVVGTATSDYGVFNVDVS
                     L"
     gene            7050..9410
                     /locus_tag="O0S08_RS37000"
                     /old_locus_tag="O0S08_37000"
     CDS             7050..9410
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS37000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_37000"
                     /product="hypothetical protein"
                     /protein_id="WP_269034177.1"
                     /transl_table=11
                     /translation="MSDSLWQKLHEKMIIAARGRLPDPPPDSQLIRVSCEVAPAALRPL
                     LEARRLTEAILGETRSGRTRPRTRTLFGDTPERATEAVVVELWNRLAKQNGARWVVVFD
                     AVERADEATLAALTQIVQQPGWLRLPLLLVFHDEPKAAAAELLAAVRARDGDSVVRGEE
                     ALASEAKPIKWSTLPPEVLRALRAGALIGPGFEVRVLAELLSIDPELVLERLQHAIDLG
                     VPVEDRGEGKFSLPSSALSALSASIIPSLAQAWHRKLGQLLGARAARAIPPPPPAPGIA
                     GIAKFQAESVDDTRVAEIIDMSHEVVDLASETAAATSGTSGAGVDAGARPVAPDTSRPQ
                     AISGEISDRVESAQSNPPRRPVQRKTVLAPPAEGARSTRRKTLVLKPEVDMPAPVELTA
                     TGKVAAATVGDPLIDNVRAAEHMRRAGDLDSAAEHLCEAAREAAAMGAPQAAVEHANGA
                     LALLATLPVGVSRQRLKARALLELGRVQWQAPGYEHGFTLARARASLEAARAELDADAP
                     VELVVDLAQALAGVHFDLGDPPSLALALAEVEEASRVLHAANDAIGAARLFNDQAAVRV
                     RMGDGAHALKLLRASRAIFDARAQDDPAALRELAESEHLLANLPLHARMRLGREEEGYA
                     IGMDHALAAERAFGELDDDRELARVWETMGRLDLKRLRLEEARLRLEAAFEVQTRIGDL
                     TGLAQTTEFLSEVLAWCGRNAEAITMLRDSVIYNRDKGSPRGLISNRQAFTALSSRFAQ
                     LPQHADGLREVEILLAAGERELGVSPPDATEER"
     misc_feature    9766..9778
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.42"
                     /tool="antismash"
     gene            10001..11497
                     /locus_tag="O0S08_RS37005"
                     /old_locus_tag="O0S08_37005"
     CDS             10001..11497
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024640.5"
                     /locus_tag="O0S08_RS37005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_37005"
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_269034178.1"
                     /sec_met_domain="T2TS (E-value: 4.9e-49, bitscore: 166.4,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRHFQCPEDRGEFRFLGPASGRVLESALTLHVLRRTNIEPEWQQ
                     RLRGFLVGHSAGADPISRLFAAAALGLTQTEDAMTALDGFLGDLAYGRRRKRALLLMLL
                     VELEVVPLARAGIMLDDFAVQAAHRFSQLHGAASRLMFGRHAGGIPEGTVPRDAAFIVA
                     CQAANGGWEQQALLTLLAMLALGPDHPAFERGLRFLRGLEREDGGIPFIPDVDVWLNAL
                     AGLALQAGSSLPEVRRQVARFLISRQHTHGGWSFTDGVQQTDSDCSALCVELLLREDAE
                     RHAPAVDRALEYFRERQRDDGGYPAYERAGESEPTMTANVLLAQCLGVGRRPELVPSMR
                     AARQFIRGSQRSDGRFETSWSLCETYSIFRVMASLEAHRAVDPGQTPDTVGERALRYLL
                     AHQRTDGGWGQAATAPSDALSSAYALAAVSLPRFATVVPPACARRAAAYLLGQQDPRTG
                     AFVSIPDQMGPRPIPYEVPVLSTVMGVWALSLTIQRLSQG"
     misc_feature    11003..11005
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11511..12392
                     /locus_tag="O0S08_RS37010"
                     /old_locus_tag="O0S08_37010"
     CDS             11511..12392
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS37010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_37010"
                     /product="hypothetical protein"
                     /protein_id="WP_269034179.1"
                     /transl_table=11
                     /translation="MSQRSTHSIPTLEQFLAAPLAEVRPVAPATMVWVVEGTRRSAALA
                     GVPAEDYGRWSVPRMNACVRMFFEHGVRHVFTPFLTPSQFGEKTPGYRERLFEYAGLIA
                     SEPEFLAPYITHGWRVRLLGGDSLPELRPYAAKLIEATPYGDHTLWCSVVAETGAPWSE
                     LLQAVVRSGARTREEAISAVYGEDIPLATLMVAFGKPLVSPEQVPPLLVGKMDAYWTQR
                     PGYRIDEREFRAILHDHAYVRRTWQEDKTGRPDEAAAFRRAWEEGPTLGLGFRLGPFWY
                     PSATGVPVGSPG"
     misc_feature    12506..12520
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.18"
                     /tool="antismash"
     gene            12581..13768
                     /locus_tag="O0S08_RS37015"
                     /old_locus_tag="O0S08_37015"
     CDS             12581..13768
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039257.4"
                     /locus_tag="O0S08_RS37015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_37015"
                     /product="WD40 repeat domain-containing protein"
                     /protein_id="WP_269034180.1"
                     /transl_table=11
                     /translation="MSNVTLIGVGTDNQLYTRNKVNGQWILVPNSGSVKSVEMLADGTL
                     MGVGTDNQLYTRARVKGQWTLVPNSSTVISATQLKDGTILGVGGDYQLYTRRSVQGQWT
                     LVPNSATILSVTELQDGTLLGVGGDHQLYTRPGVQGQWTLVPNSATVLSVTELEDGTLV
                     AAGGDHQLYTRAGVRGQWSLVPNSGSVIAVTSLLPAILGVGTDNQLYTRTGIKGQWSLV
                     PNSSTILSVAEQEDGTLLGVGGDNQLYTRTGVQGQWSLVPGSSTVRSVVVLKDGTILGV
                     GGDYQLYTRTGVQGRWTLVPNSATILSVTELQDGRLLGVGGDHQLYTRPGVQGQWTLVP
                     NSATVLSVTQLADGTLLAAGGDHQLYTRPGVNGQWTLVPKSGSVIAVAARHVHLS"
     gene            14027..16756
                     /locus_tag="O0S08_RS37020"
                     /old_locus_tag="O0S08_37020"
     CDS             14027..16756
                     /EC_number="2.7.11.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019334.5"
                     /locus_tag="O0S08_RS37020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_37020"
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_269034181.1"
                     /sec_met_domain="Pkinase (E-value: 4.5e-44, bitscore:
                     150.0, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTTLPTHSATLSVSADTLTAPSTQPPADRLTRGVLVGRYIIIDC
                     IGDGGMGQVYSAYDPDLGRKVALKLLHDDATGHQRQARLLREAQVMARLSHPNICPVYD
                     VGSFHGRVFFAMEFIDGETLRAWLRARAWEWRELLAVLLAVGRGIAAAHAEGLVHSDLK
                     PENIMLGADERPRVMDFGIARVDGAPRTEAPQSLSGLALDMESRGTRTIKGTPQYMAPE
                     QWHEDSLDARSDQFSFCIVVWEALFGERPFADGHVATHVRARQELRPRPPPQPSLAPSW
                     LRAVLLRGLSARPEDRFPTMDALLVALASGQARRRRSFIAAGAAALALVLGGAAGVRWW
                     EHEQQVAACAGVGESIFADAWNEAVRARLQANFAASGLPDAGDLAARIAGWIDTFAGRW
                     RQVRAEACLVGDVHPLGCLYDQRQRLLGLLDALAEDDPRARSGAIRIAAALPDPRTCAD
                     PVLVPSAPPAEGFHAQLVATRLRQELRRIEVSGASGHLHEARARALEVRGQAASAGLPG
                     LHAEATNVAGMLADWDSDYTEAARLLRRAVVEAGASKRDDVAADAAIRLILVVGDHQAR
                     HQEALVIGDFAEMLVRRLQQADRYRGARLLGFLAVVHRGTGALSEAEALNERALELLRR
                     ELGEVHPELSVSMGHLANIYYQQGKYRESLALHTAALANAEALYGANSIEAAACLTNMG
                     AAHTQLDEDEAALPLQERALAILERALGPEAPDVARARHNFAVALGQLGRHAQAREQIE
                     RAYRAVEATLGPTHPQTALTLLDFAFMQKEAGELEAAERNYRRVLALWEETLGTEHPQL
                     VLALNALGGLALQAQRAEEAIVVFERAIKLGETRGSPPELVADARAGLARAVWEARGDR
                     VTALALAGRAAAVFREVRGQRLPALAELEAWMQQLAPP"
     gene            complement(16770..17687)
                     /locus_tag="O0S08_RS37025"
                     /old_locus_tag="O0S08_37025"
     CDS             complement(16770..17687)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF028007.5"
                     /locus_tag="O0S08_RS37025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_37025"
                     /product="FHA domain-containing protein"
                     /protein_id="WP_269034182.1"
                     /transl_table=11
                     /translation="MAEIRRIDGAGAWFLHERSLIGRSRVCTVCLEDRKVSAEHALVRW
                     NGRAWELQDLSSRNGTFVAGRRVGVGERVSLTAGAALGFGSADGYVFAGVEPPAAFAVP
                     LDGGPQIEAQDGLLALPDSNAPEITVHRSAEHGWSMEQAGRVSEARDGDTVRSASGAWH
                     LHLPGTLMQTDEAQGDEPTIDSIGLRFRVSRDEETVEMIALHRGGVIDLKVRVHHYPLL
                     LLARARLRDAASPADRQGWIEQSDLLRQLHCDGDRLYIDIFRSRRQLADAGVADAARLI
                     ERRPGTGLLRIGVASLEIFPLLEN"
     gene            18069..19568
                     /locus_tag="O0S08_RS37030"
                     /old_locus_tag="O0S08_37030"
     CDS             18069..19568
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS37030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_37030"
                     /product="hypothetical protein"
                     /protein_id="WP_269034183.1"
                     /transl_table=11
                     /translation="MRRLAPVLLLLACGPDLPTPGDGSTSDIPGSSSAPSPTNTSGSPA
                     TTNTPTNATTSAPDDNTSTTLDPPATTSTTTGEPTLCGPACAELRDITGNLEIEPGTDP
                     QTFACVRRIDGDLEIHDLADGDILAHLGNLEEVTGGVTIRDNAGLTDVPGLGCLRSVGA
                     LRIQDNGALTSLAGLAGLRNAGSLSLQDNGALTSLAGLADLRRAGGIYLDGLPVLSELP
                     AWTFEPDNALGGLSFIDLPALTDLDVFAGMTTTNGEFYFTAIGCPALTSVVGVGDLLRS
                     ADPVFVYLRDLATLTDLAGLDGVPAFNNLDLLSLPQLASLAELEGTQTIHTLNASSLPK
                     LADLHGLEDLAETDILALADLPLLTDMSALSALTNIAVLSLDRLPALPDLSGLSSLHTI
                     SIQLSLGSCDDSPDAGLDKLVDLTGLDNLEVALNVVIGNNDDFAGFTGAPKLATVSELH
                     AVHNPSLAPGTLAAWAATLDPTPILCESQDLDMCSCFVFDP"
     misc_feature    complement(19740..19760)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.19"
                     /tool="antismash"
     misc_feature    19942..19955
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: medium, score: 18.12"
                     /tool="antismash"
     misc_feature    21000..21009
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
ORIGIN
        1 gattgcccag acccggactc ctcggacccg gacttctcgg acccggactt cccggactcg
       61 gattgcccgg acccggactt ctcggacccg gattgcccgg actcggattg cccggacccg
      121 gacttctcgg acccggactt ctcggacccg gactctgctg cttttggctc ttcggcgcca
      181 agctctcccg cgccgggatc tcccgcgccg ggctcgctcg ccctggacgg ggacgaatcg
      241 gccggaggcg tctcgcccgc cggtgacgag tcagcgctct ccggggccgc ggcttctgcc
      301 ggcagcagct ccgctcgttc atccccgtcc gaactcgcca tgcgaacgcc gagcacgacc
      361 acacccagcc cgagcagcgc gagaacagcg atgagcccgg gcggccgtcg ctgacctgtt
      421 ggtgtcggtg gtggaacgcc gggcgcgggg ggtgctttgg gcggcaccga gggctcttcg
      481 ccgaggatga tctcgctcca cttgtccgaa ggcgggggcg tcggaccacc cgcctgtgcc
      541 atcatgatga gtgaggagag tggcgttgcc gccgcgcctc gatcgcgcgc gccactgagg
      601 gccgcggtga tgatgcgatg acgatcttcg aggagctccc ccgacgcgag tccgctcggc
      661 atgggcagag cgtcgcagag cccgccccgc cgcgcaaggg cggggagcgc ggcatactcc
      721 ccagggtgtg tgctgtcgtc ggcgacgaca cgcagcgcga aacgcaggac cggggctggg
      781 aacgcccatt catgctgtct gaagagacag ccgcctcccg acgacaagcg ggctccgtgg
      841 ccgcccacca atcatgtctt gtcggaagag acagcccctc cgacgacgcc gagcgcaggc
      901 cgaccaggcg cgcgccaggc tctctcgtct acgcgttgat cgtggctttc aggcgattgc
      961 ttggcttgaa cgtcaacacg cggcgagcct cgagcatcat ctcctccccg gtcttcggat
     1021 ttcgaccgcg gcgcgtggtc ttgtagcgaa cgacgaagtt gccaaaacca ggcagcttga
     1081 cgctttcacc cgaagcgagc gtctccttga tcaactcgag aacgatctcg accatgtcga
     1141 cggcctcctt cttcgagagt ccgccaagct cgtcggacac acgctcgatg atgtctgcct
     1201 tcgtcatgtg caaggcatcc ttggagaagg atgcagaccg catgtggcgg cgaccaggag
     1261 gggaatgaag acgaggcgag actgccgggg tttgaacatg cgcatgtcct gagcagggcg
     1321 aagacgggcg ttggaccgtg cgatccgcgg accctccaag aaccccacga cggcgtcaaa
     1381 gatcaccgcg agggctgcgc gctcaccagc gcgagccgcc gcgatcacgg cggggtcctc
     1441 cgggtccttc gtgagcgtgc gaggctcggc cacgggagct gcggatcgcc gacgccgttc
     1501 gaccgcatgg gagtcggctg gctgttcgga caggcgcatc ggtgtgcccg aagaacgcat
     1561 cgacgaagtc gtcctgccat cgcagtggcc agcgtccgcc ggagccgccg gccacctcac
     1621 tgccccatcg cccagagggc gatgatcagc agcgcgagag cggcgaacac cgtgatgaaa
     1681 accatcaacc cgcggttcgg cggcggcgcc ggtcgttggg gctgcgatgc tgggggctga
     1741 ggcggcggtg tcggagccac cactgcggag gccggacgat tggcaagagc gcgcagttgg
     1801 tcacggacct cgcgagcggt ttgtggcctc tgcgcagctt cacgcgccag cagttggctc
     1861 aggaggcggt cgagttcagg gggcagatcc ggaatctcgc gcgcgagcgc cggcggtgcc
     1921 tgcgtgagct gtcgaatcgt gatgtcggac agctcgccgc cgtcccagag ctcgcgccca
     1981 gcgagacttt cccagaggat caccccgagc gcgtacatgt ccgtgcggtg atcggtcggc
     2041 tcgcctgcgg cctgttccgg cgacatgtag ccgggcgtgc ccatcacggt gccgagtcgc
     2101 gtcagggggg tcatgtcggg acctgaatcg gcgacgcggg ccagtccgaa gtccaacacc
     2161 ttgaccactg tagcgtcctc gcgggcctcg aggaggatgt tgtcgggttt caggtcgcga
     2221 tgaatgatgc cggccccatg ggctgcgacg agcgcgtcgg cgatctgggc tccgatgtca
     2281 caagccttcc gccagggcaa cttcccgctg gcgatcgtgt tcgtcagcgt gcgcccccgg
     2341 accaactgcg tgaccaggta cgcgccgccc cccggcagcg ggccgaagtc gatcgcgcgg
     2401 accacgttcg ggtgatcgat cttcgccgtc gccatcgcct cacgccgaaa gcgctcggag
     2461 atctcggcgt tgccggtgaa ctcggcgtgg atcatcttga ccgcgaccat cgtgcggagg
     2521 ctgagctgct ccgccgtgaa cacggctccc atccccccct cgccgatcag ctcacggagt
     2581 cggtagcggc cgtccagcgt gtgcccgatc catgtcgccg gcgacgcacc aggagtgggg
     2641 ttgagtgatg cggcgttgct caagatgact ccggagtcgt gggggaggcg actgggccga
     2701 gaacgggtgg gagtaccccc ggcctcgtgt gcatggtgac ctctactcgg gcggttgcag
     2761 accgacgacc gcagtctcca ggctcgatgt gcggcggtca acagcctccc gcatggcgca
     2821 ccggccgccg agtcctcgaa cgcgtgctgc ggcgcgaacc cattcacttg gaaaagttca
     2881 cgggcggccg gtccaagaag gttttcccga gcaagcggtc gcctcgatgc gcccggcgcg
     2941 agccagttac ctgggccgct tgtgctcgat gatggtgtcc ggagacggat tcatcaccaa
     3001 ttcgtgcccg ttcggaaact tcaccctgta cggtggcgca ccgtcggggc cgaggacctc
     3061 gacgatctcg ccgaccaacg gaggatcgct gaggaccgtt atgcgaatgg aatcgcccac
     3121 gtgtgcctgc atgatgaact ccttcctggc gttcttccgc tgtggccctg gccctgtcaa
     3181 gcgaggccag ccgggcccat gcggcggcgc tcgacgcgat ggcatgaaca ggacgtctac
     3241 ccacgatgcg gcatcgagtc ttcaagcccg cacgccggcg acgcggggcg ccgtgatgtg
     3301 aagcgtcccg cgaggaggcg ccgcgttgcc tcgacgggcc cacgtgcgct cccgtcgacg
     3361 gcttgtacgt gctcgtcgtc agcgcgccgc gcgacgagaa cggcgagctg tcggcgaccg
     3421 cgaagttccc cctccaggcg acgacatgct cttcctgtcg ggcatccgga gcgcctacgc
     3481 cgcggtcgcc tcgggcctga acctcgttac cgcgccaggc gctgcagtta cgcctgggac
     3541 tgggccgagg gtaatgccca ggccggcgct gggcccgctc ctcgggggct aggcattcgg
     3601 gtatagtcca ccccgctttc gcatgtcgaa cgcccccgag agcacccccc gcgagtcgcg
     3661 ctggatcggc cgtgtcgtcg acgagcgcta caagatcgtc gaggtgctcg gcgagggcgg
     3721 catgggggcg gtgttcgtgg ccgagcacct gcgtctgcgc aagcaggtcg cgttcaagac
     3781 gatcagggcc gagttcgcag cgcacaccca ggcggaggcc cgcttcgagc gcgaagcact
     3841 ggccaccggg cgcctcgacc atccccacgt cgccagcgcg atcgactacg gaccgttgcc
     3901 ggagggcggg ttctatctgg tgacgcagtt ggtccgcggt gagagcctga gcaagcggct
     3961 cgaggcgggg ccgctgccat ggccacaagt gtgtctgctc ggcagccaga tcgccgatgc
     4021 gctggcggca gcgcacgcgc tcggcatcgt ccaccgcgac ctcaaacccg acaacatcct
     4081 gctcgagcag cgccgcgacg gggcgctgca cgttcgcgtg gtcgacttcg ggatcgctcg
     4141 cgtgtcgggc gagcaggcga ccatcgccga cgtcgcgcag ccgctgacgc gcttgggcgc
     4201 cgtgatcggc acgccggggt acatgtcgcc cgaacagggc acgggccagc aggtcgactt
     4261 ccgcgccgac ctgtacgcgc tcggcgtcat cctctgggag tcgttcacgg gacagcagct
     4321 gtggcagggc gacacgctgg ttcagatgct cacgcgccag ctcgggcgcc ccgcgccgag
     4381 cctgcgcgca gatgtgcccg aggccatggc ggtgatgatc gagcggctcc tggcccgcgc
     4441 tccggcggag cgcccggaat cggcgctcga ggttcgggac gagctccgtc gtctggtgtt
     4501 cggcaacgag gtcagcctcc cgccagcggt ttccgcgagc gcagcgcttt cgtcagcgat
     4561 gtcgggcagc gcagcgagac ccctcgtggc cacgcccggc gaagtgactc acgccgacgt
     4621 acgaagcggc acgacggcag cgaccaagcc atccggagtg ctcgagcctg ggacatcccc
     4681 gcggaagagc ccccgcgggg tatggatcgg catggcgggg gcgctcgtga tcgtcctcgc
     4741 cgtgctcgtg tacggccgaa gcaagacgga cgagatcacc agcgagacgg ctgtcggcac
     4801 cgagtcggcc cctgtcgaca ccaagcccac gccgcatgcg accgtcgacg agctcatcgc
     4861 ccaggcgccg gcggcctatg ccgaggacgt caagatgctg ctcatcagca ggcacccgca
     4921 ggcccgccga ctcgcaagcg aggcgatcgc gggtgcgccg tccagagact tgaagaagat
     4981 cccggagtac ctccgcgact tcgcccggtt ggagctggcc gacgactgcg atgacaagaa
     5041 agccatcctg aagaagttcg aagcagccga ggaggtccgg gcgctcccgg ggctgaaagc
     5101 catcgctggc gggcggagtg actcctgtga gctccgcgac gagctcaccc gcctgatcgc
     5161 ccgcttcgag tgaggaacgt gagccgagcc gggcgagccg ccggcctcga cctcgagccc
     5221 gttgcccgcg gcggcgcttt gaacattcct tcgatgcttg cggtcgcggc ctcggtacct
     5281 gggcgctcga ctcgcacggt gcttctggcc gtccatcacg acggcgaccg cgctcccggt
     5341 ccgagctgcg agcacgacga ccgagtctgc gaatggtagc ctgccgggtg atcacgttct
     5401 tcagagaacg gccacaggcg agtgctcgca cttatgccaa ctttggaatc accagatttc
     5461 gtcgggtcta aattcgtcta caaacaacga agattccacc ggccgcggtc gtccgcaggc
     5521 gcatgatttt gagaggaagg acgccagcgt gcatgctatg gtcgcggcca tgcccaagtt
     5581 cgactttgtc tctgcaatcg aagatcgcaa gcgtcagctc ctcgtcgagg agctgcggaa
     5641 gcagcatgag ctcacgattg gcgagctcaa ccagctggcg cgcggcgagc tcggcccggt
     5701 gctccgctcg atcacgatcg ccgagctgat ggggtccggg ccggtgccgg gcgtctcggg
     5761 tgccgctcgc ggcgcctccc cgcggccgga ggcccgggta ccccggcgga acccgagcaa
     5821 ctcgtcctcc tcccagaata agcccctgcg caacgaggtc gtcacccgca cggcggcggg
     5881 gcgtgaggcg ttcgataagc agatcctcga ggtgatcgag gcgattggag gccccgcgag
     5941 cgcgaccgag atccagcgcc gcgtcggcgg tacgaacatg caggtgcgct cgggagtcaa
     6001 ccgtctgatt gaggccggcc atgtcacctg gacgggcaag gcgcgcggga ctcgctatta
     6061 cccggcctga gcccgcgtcg ccttcctgta agaatcggcc cgctcgcccc gcaatccatc
     6121 ccgacgtcgt gctcagccac gcttcaggtg ggagcctgaa tcgcgagaca gcgcggggcg
     6181 agactggcgg tcaactggcg ggttgcggct gccgcaacga tctgcacgaa gagacaggtc
     6241 cagggctgcg gcgcgggctc ctcgcgctcg cgtcgccggt gtcggagccg cgcaacctcg
     6301 tgtcgccgct caggcggccg cgcccccggc gccctgtgca agcagctcaa gtgcatggcc
     6361 ccgtgctcac gcgctcgccg tggcgtcagc ttcacgtcgc gggtcggcca tcgttgttgg
     6421 accgccgcgc cagcggcgat tccaaacccc ggccgcgcag tgctgcagtt ctcggctccc
     6481 cggcctgcgg tatcatgcgg cctctcgagg agaccctgcg catgcgtcgt gccccccgtc
     6541 cccatgtcct cccgcgccat gggctgctgc gcaccgtccc catcgccgcg ctgttgatag
     6601 cgagctgtac gcgtccgccg ccgcactccg taatcgatga cgctgaagcg gcgcgtctgg
     6661 cgtaccccgg cctcgatcat gcggtggacc gcgcgctcaa gctcgggttc gacggcttca
     6721 acgcggcctc gagcgcgaac atccccgagc agtccgaacc cggcgaggcc gcggggttga
     6781 tggtggtcaa tgggaaggtc gatcagggca gctcagccaa caaggggatg cggctcgagg
     6841 tcagcctcgc ggactactcg gacggactga tcgagggcgt gtacgacgtc gtctacgacg
     6901 gtggtcccaa tgggatcttt cgtcgcaagg cggggacgat tcacgtcgtg ggcaccgcga
     6961 cctccgacta cggggtcttc aacgtcgacg tcagcctgta gtgaagccgc tcggcgtcgc
     7021 tatccactgt caccaaggta ccctcgtcca tgagcgactc tctctggcaa aaactccatg
     7081 agaagatgat cattgcggct cgcggccgcc tgcccgatcc gccgccggac agccagctga
     7141 tccgcgtgag ctgcgaggtc gcaccggccg ccttgcgacc cctcctcgag gcgcgacgct
     7201 tgaccgaggc gatcttgggc gagacgaggt ccggacggac ccgtccgcgg acccgcacgc
     7261 tgttcggcga cacgccggag cgcgcgacgg aggcggtggt ggtcgagctg tggaaccgcc
     7321 tcgccaaaca gaacggtgcc cggtgggtgg tcgtgttcga cgcggtggag cgggccgacg
     7381 aggcgaccct ggcggcgctg acccagatcg tgcagcagcc cggctggctt cggttgccgc
     7441 tgctgctggt gttccatgac gagccgaagg cggccgcggc cgagctactc gccgccgtgc
     7501 gtgcgcgcga cggcgactcg gtggtgcgtg gggaggaggc gctcgccagc gaggcgaaac
     7561 cgatcaagtg gagcacgttg cctcccgagg ttctgcgcgc gcttcgtgcc ggggcgctga
     7621 tcggcccggg cttcgaggtc agggtcctcg ccgagctgct gtcgatcgat ccggagctcg
     7681 tgctcgagcg gctccagcac gccatcgatc tcggcgtccc ggtcgaagat cggggtgaag
     7741 gcaagttctc gctgccgagc tcggcgctct cggccctgtc cgcgtccatc atcccgtcgc
     7801 tcgcacaggc gtggcaccga aagctcgggc agctgctcgg cgcacgggcg gcgagggcca
     7861 tcccgccgcc ccctcccgct ccaggaatcg cggggatagc aaagttccag gcggagagcg
     7921 tcgacgacac ccgcgtcgcg gagatcatcg acatgtctca tgaggtcgtc gacctggcct
     7981 cagagacagc cgcggccacg tccggaacgt ccggcgccgg cgttgacgcc ggtgcgcgcc
     8041 ccgtcgctcc tgacacgagc cgcccgcaag ctatctccgg ggagatttca gatcgagtcg
     8101 agtcggccca gagcaaccca cctcggcggc cggttcagcg caagaccgtg ctagccccgc
     8161 ccgccgaggg cgcacgctcg acacggcgca agaccttggt tctgaagccg gaagtggaca
     8221 tgccggcgcc ggtcgagttg accgcgaccg ggaaggtcgc agcggcgacg gtcggcgacc
     8281 cgctgatcga caatgttcgg gcggccgagc acatgcgccg ggccggtgac ctcgattcgg
     8341 ccgcggagca cctgtgcgag gcggcccgcg aggcggcagc gatgggcgcg ccgcaggccg
     8401 cggtggagca cgccaatggg gcgctcgcgc tgctggcgac gctgccggtc ggcgtgtctc
     8461 gacagcgact caaggcgcgg gcgctgctcg agctgggacg ggtacagtgg caagcgccag
     8521 gctacgagca cgggtttacg ctggcgcggg cgcgggcgtc gctcgaggca gcgcgcgccg
     8581 agctcgacgc ggacgcaccg gtcgagctcg tcgtcgatct ggcgcaggcg ctggcagggg
     8641 tccacttcga cctcggtgat ccgccgtcgc tcgcgctggc gctcgccgag gtggaggagg
     8701 cgagccgcgt gttgcacgcc gcgaacgacg cgatcggggc ggcccgcctg ttcaacgatc
     8761 aggccgcggt gcgcgtccgc atgggcgacg gcgcccacgc actgaagctc ctgcgcgcgt
     8821 ctcgagcgat cttcgacgcg cgcgcccagg acgatccggc agcgctgcgc gagctcgccg
     8881 agtcggagca cctcctggcc aacttgccgc ttcatgcacg catgcggctc ggtcgcgaag
     8941 aggagggcta cgcgatcggt atggatcatg cgctcgcagc agagcgggcg tttggcgagc
     9001 tcgacgatga ccgcgagctc gcccgcgtgt gggagacgat gggccggctc gatctcaagc
     9061 gcctccgcct cgaggaagcg aggctgcggc tcgaggccgc cttcgaggtg cagacgcgaa
     9121 tcggcgacct gactgggctg gcgcagacca cggagtttct gtcggaggtg ctggcatggt
     9181 gcggtcgcaa cgccgaggcg atcacgatgc tccgcgactc ggtgatctac aaccgcgaca
     9241 aggggtcgcc gcgcgggctg atctccaacc gccaggcgtt caccgcactg tcgtcgcgtt
     9301 ttgcccaact gccgcagcac gcggacggtc tccgggaggt cgagattttg ttggccgccg
     9361 gggaacgcga gctcggcgtg tcaccaccgg acgcgaccga agagcgctga acatccttcg
     9421 gcacagcgct agcgagcggt gagcccgagc tcgagcccag gcgccgaaat cgcggctatc
     9481 gcatgctacc gccgcagata cgccgtgggc gacgtcctga cgtaccggca ggtgcgattc
     9541 gggcggtcgg tgagggcggc gaccaggccg gcccggtcgg gagacaaccc gtagtagcgg
     9601 tcacgtagct cggccgccag gccagcatcg tgaaatgagc cctgcggaaa ttccagtcgc
     9661 cggcccgcga gtgctcgtgg gcgcgcgtcg ccgccctcag ccaccgtctt acatcgcggc
     9721 gcttgagcgc agtactgcgc tttcaccggc gcgcggctgc gcgtgtcacc ttttgcaagg
     9781 tcggtgaaag atgcgaatca ccattctccg ggtatcactg caccgcggct tggcgaggac
     9841 gacgatgctc gtgacgactc atggttcgga cgaatcttcg aaacgaataa atggcgggtt
     9901 cgatcatcaa aatcgcgtga atgcgaacgc gtcggctgcg cagatcccac ttcctgaccg
     9961 agccgagctc gagcgcggtc gggacagggg acttgagcac atgctccgcc acttccagtg
    10021 cccggaggat cgaggtgagt tccgcttcct cggccctgcg agcggccggg tcctggaatc
    10081 tgcgctcacg ttgcacgtcc tccgacgcac gaacatcgag ccggaatggc aacagcggct
    10141 gcggggcttc ctggtgggcc acagcgcggg agcggatccc atcagcaggc tcttcgcggc
    10201 cgccgctctc gggctgacac agaccgagga cgccatgacg gcgctggacg gcttcctcgg
    10261 cgatctcgca tacggccgcc gccggaagcg ggccttgttg ctcatgctgc tggtcgaact
    10321 ggaggtggtg ccgctcgcgc gcgccgggat catgctggac gacttcgcgg tgcaggcggc
    10381 ccaccgattc agtcagttgc atggggccgc ctcgcggctc atgttcggac gacatgcggg
    10441 cggtatcccc gagggcacgg taccgcgcga cgccgctttc atcgtggcgt gccaagccgc
    10501 caacggcggc tgggagcagc aagcgctcct cacgttgctg gcgatgctcg ctctcggccc
    10561 cgaccaccca gccttcgagc gcggcctgcg gttcctacgc gggctcgagc gtgaggacgg
    10621 gggcatcccg ttcattcccg acgtcgatgt atggctcaac gctctggccg gcctcgccct
    10681 gcaggcgggg tcctcgctgc ccgaggtgcg ccggcaggtg gcgcggttct tgatctcgcg
    10741 ccagcacacc cacggcgggt ggagctttac cgacggcgtc cagcagacgg atagtgactg
    10801 ctctgcgctc tgcgtcgagc tgttgctgcg cgaagacgcg gagcgccatg ctcctgcggt
    10861 cgaccgcgcg ctggagtatt tccgcgagag gcagcgagac gacggcggat acccggcata
    10921 tgagcgcgcg ggtgagtccg agcctaccat gaccgccaat gtcctcttgg ctcagtgcct
    10981 tggggtcggc cggcgaccgg aattagtgcc ttcgatgcgc gccgcgcggc agttcattcg
    11041 tggcagccag cgcagcgacg gtcgcttcga gacgagttgg agcctgtgcg agacctactc
    11101 catctttcgc gtgatggcct cgctggaagc tcaccgggcc gtggaccccg ggcagacccc
    11161 ggacactgtg ggggagcgag cgttgcgtta cctgctcgcg catcagcgga ccgacggcgg
    11221 ctgggggcag gccgccactg ccccttctga cgccctgagc agcgcgtacg ccctcgcagc
    11281 tgtgagtctg ccgcgcttcg ctaccgtcgt tccgccggca tgtgcgcggc gagcagccgc
    11341 atacctgctg ggacagcaag atccgcggac tggcgcgttc gtgtcgatcc cggatcaaat
    11401 gggacctcgg ccgataccct acgaggtccc ggtgctgagc accgtgatgg gtgtatgggc
    11461 tctatcgctg accattcagc ggttgtccca gggataggag gattccgaca atgtcacaga
    11521 ggtccacgca ctcgatcccc acgctcgaac aattcctcgc agccccgctc gcggaggtgc
    11581 ggcctgtggc gccggcgacg atggtatggg tcgtggaggg cacccgtcgc agcgcggcgc
    11641 tggccggcgt ccccgccgag gactatgggc gctggtcggt gccgcggatg aacgcctgcg
    11701 tgcgcatgtt cttcgagcac ggcgtccgtc acgttttcac gccgtttctg acgccgagcc
    11761 agtttggaga gaagacgccc ggctaccgtg agcgcttgtt cgagtatgcc gggctcatcg
    11821 ccagcgagcc ggaattcctc gctccgtaca tcacgcacgg ctggcgcgtg cggctcctcg
    11881 gaggcgacag cctgccggaa ctgcggccct acgccgcgaa gttgatcgaa gcgaccccgt
    11941 acggcgatca cacgctgtgg tgctccgtgg tggccgagac gggagcgcca tggagcgaac
    12001 tgctgcaggc ggtagtccgc agcggcgcac gcacgcgcga ggaggccatc tctgcggtct
    12061 atggtgagga catcccactg gccacattga tggtcgcgtt cggcaagccg ctcgtgtcgc
    12121 ccgagcaggt gccaccgctg ctcgtcggca agatggacgc ctactggacg cagcgtcccg
    12181 gctatcgcat cgacgaacgc gagttccggg cgatcctcca cgatcacgcg tatgttcgac
    12241 gcacctggca ggaggacaag acgggtcgcc ccgacgaggc ggcggcgttc cgccgcgcgt
    12301 gggaagaagg accgacgctg gggctgggct tccgcttggg tccgttttgg tacccgagcg
    12361 cgaccggggt gcctgtcggg tcgccgggtt gacgccgcgc ctcccctgtc aacctcgggg
    12421 gtttgctcgc cgacatcaat ctcacaggcg acctccccgg gcgacgggtc gtccgctcgc
    12481 ttcgacctcc tcttacccat cgaaaatctc actttgaact tcttgaacgc gaaataaatg
    12541 gctcagtgat tcgaagacac gtacagaagg agatgaacaa atgagcaatg taacccttat
    12601 tggcgttggt acggacaatc agctctacac gcggaacaag gtgaacggcc agtggatcct
    12661 ggtgcccaac agcggctcgg tcaagtcggt ggaaatgctg gcggacggca ccctgatggg
    12721 agtgggcacg gacaaccagc tctacacgcg agcccgcgtg aagggccagt ggaccctggt
    12781 gcccaacagc agcacggtca tctcggcgac ccagctgaag gacggaacca tcctgggggt
    12841 gggcggcgac taccagctct acacgcggcg tagcgtgcag ggtcagtgga ccctggtgcc
    12901 caacagcgcc acgatcctgt cggtgaccga gctgcaggac ggcactctgc tcggcgtggg
    12961 cggcgaccac cagctctaca cgcggcctgg cgtgcagggt cagtggaccc tggtgcccaa
    13021 cagcgccacg gtcctgtcgg tgaccgagct ggaggacggc accctggtgg cggcgggcgg
    13081 agaccaccag ctctacacgc gggcgggcgt gcggggccag tggtccctcg tccccaacag
    13141 cggctcggtc atcgcggtca cctcgctgct cccggccatc ctcggcgtcg gtacggacaa
    13201 ccagctctac acgcggaccg gcatcaaggg ccagtggtcc ctcgtgccga acagcagcac
    13261 catcctgtcg gtggccgagc aggaggacgg caccctgctg ggagtaggcg gagacaacca
    13321 gctctacacg cggaccggcg tgcagggcca gtggtccctc gtgccgggca gcagtacggt
    13381 ccgatcggtg gtcgtgctca aggacggaac catcctgggg gtgggcggcg attaccagct
    13441 ctacacgcgg acgggcgtgc agggccggtg gaccctggtg cccaacagcg ccacgatcct
    13501 ctcggtgact gagctgcagg acggacggtt gctgggagtg ggcggagacc accagctcta
    13561 cacgcgccct ggcgtgcagg gccagtggac cttggtgccc aacagcgcca cggtcctgtc
    13621 ggtaacccag ctggcggacg gcaccctgct ggcggcgggc ggagaccacc agctctacac
    13681 gcggccgggt gtgaatggtc agtggaccct cgtgcccaag agcggctcgg tcatcgcggt
    13741 ggccgctcga cacgtccacc tctcttgatc gccgtcggcg cgtagacgca gtgctcgtcg
    13801 agctcgaggt gcttctcgcc tccctcgcgc attcggccgc gcgtaacacg cggagcgtcc
    13861 ccgctccccc ggcgctccga gcaccggccg gcgatctgga ccatcacgat gccgatccgg
    13921 gggattacga gcgcgcccac gccagcgcgg tcatggacac cgtcgtttgc gacgaagcgc
    13981 cgacaccgtc ggtggcggcc gggtatcctc ggtcgccgcc tgattcatgt ccacgacgct
    14041 gcccacgcac tcggcgacgc tctcggtgag cgccgacacc ctcacggccc cgtccaccca
    14101 gccgcccgcg gatcgcctca cccgcggcgt gctcgtcggt cgatacatca tcatcgactg
    14161 catcggcgac ggaggaatgg ggcaggtcta ttcggcgtac gacccggatc tcggtcgaaa
    14221 agtcgcgctc aagctgctgc acgacgatgc gacgggccac cagcgccagg ccagacttct
    14281 ccgagaggcg caggtgatgg cacgcctgtc acacccgaac atatgcccgg tgtacgacgt
    14341 ggggagcttc cacgggcggg tgttcttcgc catggaattc atcgatgggg agacgctccg
    14401 ggcgtggctg cgagcgcgcg cgtgggaatg gcgggagctc ctcgcggtgt tgctcgccgt
    14461 cggtcgcgga atcgcggcgg cgcacgcgga ggggctggtg cacagcgacc tcaagcccga
    14521 gaacatcatg ctcggcgcag acgaacggcc gcgggtgatg gacttcggga tcgcccgcgt
    14581 ggacggagcg ccgcgcacgg aggcgccgca gtccctgtcc gggctcgcgc tcgacatgga
    14641 gagcagaggg accaggacga tcaaggggac cccgcaatac atggcgcccg agcagtggca
    14701 cgaggactcg ctcgacgcgc gctccgacca attctcgttc tgtatcgtgg tgtgggaggc
    14761 gctgttcggc gagcggccgt tcgccgacgg ccacgtcgcg acgcatgtgc gggcgcggca
    14821 ggagctccgc ccgcgcccgc ctccgcagcc ctccctcgcg ccctcgtggc tgcgcgccgt
    14881 cctcttgcgc ggtctgtcgg cgcgaccgga ggaccggttt cccacgatgg acgccctgct
    14941 ggtcgccttg gcctccggac aggccaggcg tcgccgctcc ttcatcgccg ccggagcggc
    15001 cgcgctggcg ctcgtgctcg gcggcgccgc tggcgtgcgc tggtgggagc acgagcagca
    15061 ggtcgcggcg tgcgcgggcg tgggcgagag catcttcgcg gacgcgtgga acgaggccgt
    15121 gcgagcgcgc ctgcaggcga acttcgccgc ctcggggcta cccgacgccg gcgacctcgc
    15181 cgcgcggatc gccgggtgga tcgacacctt cgcgggccgc tggcgacagg tccgcgccga
    15241 ggcgtgcctg gtcggcgacg tgcacccgct cgggtgcctg tacgatcaac gccagcggct
    15301 cctcggcctg ctcgacgcgc tcgcggagga cgaccctcgc gcccggtccg gagcgatccg
    15361 catcgccgca gcgctgccgg acccgaggac ctgcgccgac cccgtgctcg tgccgtccgc
    15421 gccgccggcc gaaggattcc atgcgcaatt ggtggcgacc cgcctgcggc aggagctgcg
    15481 gcgcatcgag gtctccggag cctccgggca ccttcacgag gcgagggcgc gggcgttgga
    15541 ggtgcgtgga caggccgcga gcgcggggct cccgggcctc cacgccgagg cgacgaacgt
    15601 cgccgggatg ctggccgact gggactccga ttacaccgag gccgcgcgac tgctgcgacg
    15661 cgcggtcgtg gaggctggcg catcgaagcg cgacgacgtc gccgccgacg ccgcgatccg
    15721 gctgatcctc gtcgtcggtg accaccaggc tcggcatcag gaggcgctgg tgatcggcga
    15781 cttcgcggag atgctcgtgc gacgactcca gcaggccgat cgctaccgcg gcgcgcggct
    15841 gctcggtttc ctcgccgtcg tccaccgggg gaccggcgcg ctgtccgagg ccgaggcgct
    15901 caacgagcga gcgctcgagc tgctgcggcg cgagctcggg gaggtccacc ccgagctgtc
    15961 ggtgtcgatg ggccacctcg cgaacatcta ctaccagcaa ggcaagtacc gcgagtcgct
    16021 ggcgctgcac accgcggcgc tggcgaacgc cgaggccctg tacggcgcga acagcatcga
    16081 ggccgcggcg tgcctcacca acatgggcgc tgcccacacc cagctcgacg aggacgaggc
    16141 ggcgctgccg ttgcaggagc gggcgctggc gatcctcgag cgcgcgctcg ggcccgaggc
    16201 cccggatgtc gcgcgtgcgc gccacaactt cgcggtcgcg ctgggccagc tcggtcgaca
    16261 cgcgcaagcc cgcgagcaga tcgagcgcgc ctaccgggcg gtcgaggcca cgctcggccc
    16321 gacgcacccc cagacggcgc tcaccctcct cgatttcgcc ttcatgcaga aggaagccgg
    16381 cgagctcgag gcggccgagc ggaactaccg ccgcgtcctg gcgctctggg aggagacgct
    16441 cggcacggag cacccgcagc tcgtcctcgc cttgaacgcg ctcggcgggc tcgccctcca
    16501 ggcgcagcgc gccgaggaag cgatcgtcgt cttcgagcgg gccatcaagc tcggcgagac
    16561 ccgcggctcg ccgcccgagc tcgtcgccga cgcccgtgcg gggctcgctc gcgctgtgtg
    16621 ggaggcccgg ggcgatcggg tcaccgcgct cgcgctggcg ggcagggccg ccgccgtctt
    16681 ccgcgaggtc cggggccaac gcctcccggc gctcgccgaa ctcgaggcct ggatgcagca
    16741 gctcgcccct ccgtgaggct ggcctcgtct cagttctcga ggagcgggaa gatctcgagc
    16801 gacgccacgc cgatccgcag cagccccgtc ccggggcgcc gctcgatcag ccgggccgcg
    16861 tcggcgaccc ccgcgtcggc gagctgacga cggctgcgaa agatgtcgat gtacagccga
    16921 tcgccgtcgc agtggagctg gcggagcaag tcgctctgct cgatccaccc ctggcgatcg
    16981 gcgggcgagg ccgcgtcacg caggcgcgcg cgcgcgagca gcagcagcgg gtagtgatgg
    17041 acccggacct tgaggtcgat cacgccgccg cgatggagcg cgatcatctc cacggtctcc
    17101 tcgtcgcggc tgacgcggaa ccggagaccg atcgaatcga tcgtgggctc gtcgccctgc
    17161 gcctcgtcgg tctgcatcaa agtcccgggc aggtggaggt gccatgcccc gctcgccgaa
    17221 cggacggtgt cgccgtcgcg tgcctcgctc acgcgacccg cctgctccat cgaccacccg
    17281 tgctcggcgc tgcgatgcac cgtgatctcg ggcgcgttcg agtcgggcag cgcgagcagg
    17341 ccgtcctgcg cctcgatctg cgggccgccg tcgagtggta cggcgaaggc cgccggcggc
    17401 tcgacgccgg cgaacacgta gccgtcagcg ctgccgaagc cgagcgccgc ccccgcggtc
    17461 agcgacacgc gctcgccgac gccgacccgc cggcccgcga cgaaggtgcc gttgcggctg
    17521 ctcaggtctt gcagctccca cgcgcgcccg ttccagcgca cgagcgcatg ctccgccgac
    17581 accttgcggt cttcgaggca gacggtgcat acgcgagagc ggccgatgag gctgcgctcg
    17641 tggagaaacc acgctcctgc tccgtcgatc cggcgaatct cggccatggc gcggccgcac
    17701 tgtagcgcaa cgcgagcccg tggacccgct ctcggcgcgt ccgcgggacc atcgcctcgc
    17761 cgcgagcgcg ggcgcgaacc ctgcgcggcg ccgcacttgc gagtccggtt gatccgcgcg
    17821 cccttggcgt tggccgagct cgagcagctc ggactgcagc accgccgatc agaagggcgc
    17881 gccgagccag cgatagatcg cctcattcgg gtccatccag aggaactccc gtcgctggcg
    17941 acggacacgt gcttcagcga cccttcgatg ccttcccact cgtcctccgc atatgtcgcg
    18001 acggaggttc cgctcgctca cgctattatc gagcgggagg cggcctcaaa cggagataaa
    18061 gtggcgagat gcgccgcctc gcccccgtcc tgctcctcct cgcgtgcggc ccggacctcc
    18121 cgacccccgg cgacggatcc accagcgaca tccccggctc gtcctccgcg ccctcgccga
    18181 cgaacaccag cggctcgccc gcgaccacca acacgcccac gaacgccacg acgagcgccc
    18241 ccgacgacaa cacgtcaacg acgctcgacc cgcccgccac cacatcgacc acgaccggcg
    18301 agccgaccct gtgcggcccc gcgtgcgccg agctgcgcga catcaccggc aacctcgaga
    18361 tcgagcccgg cacggaccca cagaccttcg cctgcgtccg ccgcatcgac ggcgacctcg
    18421 agatccacga cctggcggac ggcgacatcc tcgcgcacct cggcaacctc gaggaggtca
    18481 ccggcggcgt gacgatccgg gacaacgccg gcctcaccga cgttccgggc ctcggctgcc
    18541 tgcgcagcgt cggcgccctc cgtattcaag acaacggcgc cctcaccagc ctcgccggcc
    18601 tcgccggcct gcgcaacgcc ggcagcctca gtcttcagga caacggcgcc ctcaccagcc
    18661 tcgccggcct cgccgacctc cgccgcgccg gcgggatcta cctcgacggc ctcccggtcc
    18721 tgagcgagct ccccgcatgg acgttcgaac ccgacaacgc gctcggcggc ctcagcttca
    18781 tcgacctccc ggccctgacc gacctcgacg tgttcgccgg catgaccacc accaacggcg
    18841 aattctactt caccgcgatc ggctgccccg cgctgaccag cgtggtcggc gtcggcgacc
    18901 tgctgcggtc ggccgacccg gtgttcgtct atctccgcga cctggccacg ctcaccgacc
    18961 tcgccggcct cgacggcgtc cccgcgttca acaacctcga cctcctgtcc ttgccgcagc
    19021 tcgcctcgct ggccgagctc gagggcaccc aaacgatcca caccctgaac gcttcctcgc
    19081 tgccgaagct tgccgacctc cacggcctcg aggacctcgc cgagaccgac atcctcgccc
    19141 tcgccgacct cccgctcctc accgacatgt ccgccctgtc cgccctgacg aacatcgcgg
    19201 tcctctccct cgaccgccta cccgccctgc ccgacctgtc gggcctgtcg tcgctgcaca
    19261 ccatcagcat ccagctcagc ctcgggtcgt gcgacgacag ccccgacgcc ggcctcgaca
    19321 agctcgtcga cctcaccggc ctcgacaacc tcgaggtcgc gttgaacgtc gtgatcggca
    19381 acaacgacga cttcgccggc ttcaccggcg cccccaagct cgcgaccgtc agcgagctcc
    19441 acgccgtcca caacccctcg ctcgcccccg gcactctcgc cgcctgggcc gccaccctcg
    19501 accccacccc gatcctgtgc gagagccagg acctcgacat gtgcagttgc ttcgtattcg
    19561 acccgtgacg cgaagcctca ccgcatcgcc gccacccgcc ccgcgtagaa cttctcgacc
    19621 tcggcctgcc accgctccgg cgccttcgcc agcgcccgcg atgaagcggg taccgccgag
    19681 tcaggtgcgg tggcgcaagg agcgggagct gttgcatcac gccctatccc gctcacgcgg
    19741 gatcgtcggt ccgacgatct caaaggtcgg acggggagat gccgccccgg cccgcatccg
    19801 cggaccctcg gtgttctggc actggacccg gcgagagtac tgtggcttgg aatttcccaa
    19861 gcgcactcag tagacgctgc caacccttcg ccggccgaag gtacaccgag acgaggcccc
    19921 ccttgcttcc gagattcgct tcgaatgttc atgcacaaac gggcctcgtg ctggcgacgg
    19981 tgctagcgat cgcgttgccc gaggccgagg cccacgccga ctgcgggtgc gacggcacga
    20041 tcaccgccga cggcgacgga ccctgcctgc gctacgcggc cccgtcgggc cccggcaacg
    20101 acatcacgtt ccgcttcgcc gaagcgtacg agtgcgggca gtacgtgacg ggcgagttct
    20161 tcgtcgtcgc ctcgggcgca gcgatcacta tcgccgcgat cacgcccgac ggtgcgccgg
    20221 gtcgtcacgg tgtcgacgtg aatcccgatc cgaacggacc gcagcgctgg gacgatcgcc
    20281 tcggcgacta cgccgacgcg gtcggcttgc cgctcgacgt cgcagcgaac agctcggtcg
    20341 tcaagtacgt gtccgacaat cccgccggtg attgcgacgg cgatgcggac gagaaatcat
    20401 gcggacggtt cgccgcggtg gtgacgatcg tggacgcggc gcccgacgat ccgagcaccg
    20461 cgtttcgtcc gccgttcgtc ggcgcggaca agccgacgtt gtccgcggcg acgttgcaga
    20521 cgcaattgtt gtcgcggctg tcggccgact gcgccgatgt gcccacgctc gcaaccgccg
    20581 aggcgtggac gcggcacctg cggctcgact acacgagcga ctcggtcacg tgcgatctga
    20641 tgccgccgga agatgcgatc ccgaacggcc ggccgtggtc gaccgacatc tgggccgacg
    20701 acaccgacgt gcatgggtgg ctgcacctgg ccgacgtctg cgacgcaccg ccgtgcacgc
    20761 ccgagcagga tctcgcgacg aagatgcccg tgctcgtcgg ctacgtgcag cacggcatcg
    20821 acgtgtgggg cgtcgaccgg caggacgcga gcctgttccg cggcggcgga ggcaacggcg
    20881 gcggcaagct gcacgcgtac gtgttcgcgg cgacgatgct cgccgacgcg gagatgctcg
    20941 ccgatctcgc ggcgatcgac gaggagcgct tcttcgagag cgcgagctac tacgcgggcg
    21001 aaggcggcgt cgcgctgtgg ggccagccga ccggcgacga ggcggcgtac tggaacgact
    21061 tcggtgatca gtcgacgcgg acgatccgcg acccgtacca ctccatcgac ggcggcttcg
    21121 agcccggcgg ctggtatcag gacaacacgg cgaagccgac gcagtacacc gcgctcctga
    21181 tgcggatcat gccggctttg caggcgaact ggccggtgaa cggcgacgtc gtgctcgcgt
    21241 atgcggatcg ctgggtcgag cacggcgcgc tgacgcagcc ggatgactgc gcgccgatcg
    21301 gcggcgagta cggcgtcgac tacggtcccg acggcatggg cggctgcatc gcagggggcg
    21361 gccgcgtgcc cgagctcgac ggcaacaacg cgaacggagg caatcgttcg cgcccgttcg
    21421 gcgagtgcat gtggcagagc tttcgcgcct gcgccgagga ctgctcgtgc ccggggcaat
    21481 cgtgcaagag cgcgagc
//
