LOCUS       NZ_CP114040            22407 bp    DNA     circular CON 26-AUG-2024
DEFINITION  Nannocystis poenicansa strain FL3 chromosome, complete genome.
ACCESSION   NZ_CP114040
VERSION     NZ_CP114040.1
KEYWORDS    RefSeq.
SOURCE      Nannocystis poenicansa
  ORGANISM  Nannocystis poenicansa
            Bacteria; Myxococcota; Polyangia; Nannocystales; Nannocystaceae;
            Nannocystis.
REFERENCE   1  (bases 1 to 13228663)
  AUTHORS   Ahearne,A., Stevens,C. and Dowd,S.
  TITLE     Minimal conservation of predation-associated metabolite biosynthetic
            gene clusters underscores biosynthetic potential of Myxococcota
            including descriptions for ten novel species: Archangium lansinium
            sp. nov., Myxococcus landrumus sp. nov., Nannocystis bai
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 13228663)
  AUTHORS   Ahearne,A., Stevens,C. and Dowd,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-NOV-2022) Biomolecular Sciences, University of
            Mississippi, Faser Hall 407, Oxford, MS 38655, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2021
            Assembly Method                   :: IPA v. 10.1.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 250x
            Sequencing Technology             :: PacBio Sequel IIe
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_026965555.1-RS_2024_08_26
            Annotation Date                   :: 08/26/2024 12:45:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,229
            CDSs (total)                      :: 10,129
            Genes (coding)                    :: 10,068
            CDSs (with protein)               :: 10,068
            Genes (RNA)                       :: 100
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 9 of 61
            Pseudo Genes (incomplete)         :: 52 of 61
            Pseudo Genes (internal stop)      :: 2 of 61
            Pseudo Genes (multiple problems)  :: 2 of 61
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:28:22
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 8956328
            Orig. end                         :: 8978735
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP114040.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22407
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="27"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22407
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22407
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12407](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12407)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(484..2454)
                     /locus_tag="O0S08_RS34245"
                     /old_locus_tag="O0S08_34245"
     CDS             complement(484..2454)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025702.5"
                     /locus_tag="O0S08_RS34245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_34245"
                     /product="DUF4397 domain-containing protein"
                     /protein_id="WP_269033640.1"
                     /transl_table=11
                     /translation="MFRKRLTTMGPTRALSVFAITLALLGCGNDTRDPANETGAEVRVV
                     HLSPDAPSIDAFVDGQDTLVTNLAFTQGSQPANVGVGQHSIEVAAAGTGAGAAVATLAE
                     ALLEEGRRYTAFAFGELAEVQVSVVEDSTQGLASGHVRVRVVHTGAGVGNVDVYAIGAS
                     GSPDLIAENLRYGTSAEPVDLPTDPFVAGLDVDDDGNPDLLYSIPSLPAGVVVNVFATV
                     DDAGAAFLLAQLPDGTTRIDAAQQRLRVVHLSPDAPAVQPLFAGAAPAEFGEIAFPAST
                     DYASISVPSGTIDITTDGTVATSVLSAELTFEEGASYTAAAIGRVAELGALVFKDDREG
                     LEDSEIRVRAIHGAPDIGPVDVYQVAADGSATGILSDLDFGAAAEPLDLPPGAYTLGVD
                     VNDDAKPDLYFELPELPGGTLANVYVTQEDAGQPFVLAQLDGATTARIDASESQVRVLH
                     LSRDAPNVDVYAGGERVVTDLAFKDQSTFLTVPSGTLGLAVTAAGMPVETAVVDAEASL
                     LPGRAYTVVAYDDLASIGALVLADDASGLAQSDIRVPITHVAPEVTRGDIYVLLDGGTT
                     FGTQLVDDFGFGETPEAIDVPAGMYTIGFDAEADGDVQAIFDLPLLTPGTYARAYVYQE
                     ADDSVAVLVQLANTVTVVPAN"
     misc_feature    complement(2441..2454)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.49"
                     /tool="antismash"
     gene            complement(3066..3905)
                     /locus_tag="O0S08_RS34250"
                     /old_locus_tag="O0S08_34250"
     CDS             complement(3066..3905)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009949809.1"
                     /locus_tag="O0S08_RS34250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_34250"
                     /product="NAD(P)H-binding protein"
                     /protein_id="WP_269033641.1"
                     /transl_table=11
                     /translation="MTTQLQHPATILVTGATGTVGRPLVHQLVAAGHRVRALSRRPAQA
                     DLPPDVEVVAGDLADVASLARAFAGVSAVHLITFAGEGESLVDGDELVRLAERSGVRRA
                     TVLGGWDETSVERALEGSAIGWTRLEPVEFMANALEWAQSIRQGGVVRMLAAWPSAVVH
                     EADIAAVAATALTQDGHEGRRYSLSGPEALTPAERVARIAAAVGRPIAFEALDEARERE
                     RLRSYGYSEDYVEFGIRLARDPPAEAARIVPTIEQVTGRPARTFAAWAREHADAFRA"
     gene            complement(4016..5221)
                     /locus_tag="O0S08_RS34255"
                     /old_locus_tag="O0S08_34255"
     CDS             complement(4016..5221)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.5"
                     /locus_tag="O0S08_RS34255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_34255"
                     /product="hybrid sensor histidine kinase/response
                     regulator"
                     /protein_id="WP_269033642.1"
                     /transl_table=11
                     /translation="MHTSVSVLLIEDDRDDYLLTSELLEEIGEGTYVLQWADCYEDGVE
                     ALFTGAPDLCLLDYRLGEKTGLELLREVVARGCTTPIVLLTGQSERSLDVEAMKAGAVD
                     YLVKGEFGPRQLERSIRYAVERNRSLKALRELNAELQHARNQATAASHAKSMFLASVSH
                     EFRTPLNAILGYSELLHEQLVENHDQELADDVRRIHSAGTHLLSLVSDILDLSKIEAGK
                     LDLVTHAFDLEALIVEINEAIRPLVGRNENSYCCRCNGVGEMVSDPTRLRQVLLNLLGN
                     ACKFTSRGSIELLVERRQACSRDFDTAGETMPLPGVDCVEFTIRDTGIGMTTAQMQRLF
                     AGFSQVDADVTRRYGGTGLGLSISRRLCRMMGGEIFVDSEFGVGSTIRVRLPARIAAVV
                     PA"
     gene            complement(5245..6417)
                     /locus_tag="O0S08_RS34260"
                     /old_locus_tag="O0S08_34260"
     CDS             complement(5245..6417)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.5"
                     /locus_tag="O0S08_RS34260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_34260"
                     /product="hybrid sensor histidine kinase/response
                     regulator"
                     /protein_id="WP_269033643.1"
                     /transl_table=11
                     /translation="MRRRISVLLVEDDEDDFIMTQALLSEIDEPKCDLTWAQSFEEGLS
                     RLVDGSFDVCLLDYALGERTGMELLAQSATAGVEVPIIFLTGQDEHRLDVEATRLGAAD
                     YLVKSRIRADLLERSIRYALERARSLSALRLLNRELELTRDQAVRANQAKNDVLTAVSQ
                     TCRESLGTIVACNDALEARFAGRDAVAEGYAREVREACRTLERLLTDVLDMSPSASEAP
                     VVQPRSLALAPFIQEVVAAVRPLVGHNDNTLEVSCADDIGAIETDPAHLRRVLLTLLAN
                     TCKFARRGRIHLSVTRRSEGGVDGVELAIRASGLWMTPAQLELLFASIPQADAGVAPRG
                     AWTESGISGSRRVCRLLGGELFVETEGARRSVLRVWVPDRWAAGGEHRPS"
     gene            complement(6526..6969)
                     /locus_tag="O0S08_RS34265"
                     /old_locus_tag="O0S08_34265"
     CDS             complement(6526..6969)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018479232.1"
                     /locus_tag="O0S08_RS34265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_34265"
                     /product="response regulator"
                     /protein_id="WP_269033644.1"
                     /transl_table=11
                     /translation="MRSRRPITILIADDDPEDRMLAEEALRESRLVNDIRFVDDGEDLL
                     DYLYRRNAYAGSDPPRPDMILLDLNMPRMDGREALKVIKGDAELRRIPVVVLTTSKAEE
                     DIYRTYDLGVNSFIIKPVTFDSLVGIMKILGAYWFEIVEVPSS"
     gene            complement(6966..8462)
                     /locus_tag="O0S08_RS34270"
                     /old_locus_tag="O0S08_34270"
     CDS             complement(6966..8462)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.5"
                     /locus_tag="O0S08_RS34270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_34270"
                     /product="ATP-binding protein"
                     /protein_id="WP_269033645.1"
                     /transl_table=11
                     /translation="MPDYPALFALAHEPFICLDREGRLAVVNQAAAQFLESTSAQLLGQ
                     SLADQVHPDDRERVSTGLKRANEDGITVELTCRLRCAGASYRAVTLRCGRDRSLELLVI
                     AVRELTDLDELRHQRDDARRRLAAVFETMHDIVFTTDEHGVLNGVNRVPPGLTVAQTIG
                     TPMLAFAAPEEQEPMRARYDEVRETGKLIAYETVAMYPDGRKENYASRLGPIMEGDRSI
                     GVVLITRNVTQERQAEEAKRYAEQQLRDYMQQLERSNRELERFASVASHDLQEPLRKIQ
                     AFSDRLRDKFEEALADTGRDYLERIRSAAKRMQDLINDLLMFSRISAKEQAYAKVNLTK
                     IAKSVLSDLEVRIEENEAEVKLGELPTIEADPVHMRQLLQNLIGNALKFTRPDVKPVVQ
                     VTWEPVPPAERGPDDPEMVKIHVTDNGIGIEPRHHDRIFSIFERLHGRGKYEGTGVGLA
                     VCRKIVEQHRGYIKVASVPGEGTTFTILLPIRQPERSQRT"
     gene            complement(8608..9999)
                     /locus_tag="O0S08_RS34275"
                     /old_locus_tag="O0S08_34275"
     CDS             complement(8608..9999)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.5"
                     /locus_tag="O0S08_RS34275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_34275"
                     /product="cytochrome P450"
                     /protein_id="WP_269033646.1"
                     /sec_met_domain="p450 (E-value: 3.5e-83, bitscore: 279.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTLLHPRAEQLLRLPGPAGYPLVGALPAILREGIFEYVERCWRE
                     YGDFFQIPTGGRSRIIFTAHPDAIERILHTRVDNYYKGKGYDPIRPLLGNGLVTSTGDF
                     WVRQRKLTQPAFHMDNLRRMVPVMARCVDDMLVEWEARRRDDAVLDLHAEIMHLTQRIV
                     GFTLFGMDLSDREGASSRAVTESLEIAGQRMNRGAMALPLSVPTPANLRFRRALRTLDG
                     IVYDIIGHARKAGPESQPTLLRLLMEARDDGTGDGMSDRQLRDEIVTQYVAGHETTALI
                     LTWTFWLLGQHPDVYAKVCEEIAGLGLTGVPTIEDLDRLTYTRMVFDEVMRLRPPIWAQ
                     TREVREDDVLLARRIPAGSFIMFSAYFCHHHPAFWDEPEAFRPERFAPEKVRARHRYAH
                     IPFSAGARACIGKRYAIYELSTALVLILSRFRIDVLPDQHVGIRPTATVHPDRPIYARL
                     RGAGR"
     gene            complement(10001..10882)
                     /locus_tag="O0S08_RS34280"
                     /old_locus_tag="O0S08_34280"
     CDS             complement(10001..10882)
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.4"
                     /locus_tag="O0S08_RS34280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_34280"
                     /product="terpene synthase family protein"
                     /protein_id="WP_269033647.1"
                     /sec_met_domain="T1TS (E-value: 4.5e-11, bitscore: 42.0,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRIAAAVDQVLLARIMAWAADFEDFAVHHAADGLYVAEACVDPQ
                     VDGREEVFLIALVSAYWFWFDDRSDKFLREQQTPVDWDTLIAYGEDEPPRGGADTPEVR
                     FFQRLCDLLAPLAGSRDEHRWFRVGSAKVFRAMFAEERMSRDAEARSLVECIETGAHST
                     TLPSILTAAYLVRRLDRPRRHDDPRIANVERYLYLSQRLLNDLQSAEKERREGHAGRVS
                     NAVLLLERDLSPAQARAFVEAQRQGYERLLQHNLDRLGARDPFAATLSRLVRCIHRWYA
                     TGPLRFETDLAR"
     gene            complement(10884..12407)
                     /locus_tag="O0S08_RS34285"
                     /old_locus_tag="O0S08_34285"
     CDS             complement(10884..12407)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024640.5"
                     /locus_tag="O0S08_RS34285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_34285"
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_269033648.1"
                     /sec_met_domain="T2TS (E-value: 1e-38, bitscore: 132.4,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAACLGLAVEHCISLQRPDGSWEVAPDGRIFETALAGYALAHTPG
                     RLDRRAVARARAWVESAAPQDHHPVSFLLEDTLRRILVGAGGVVDLTAPELDGPVLASR
                     TMLLHTLALHAGLEVRARRSEDELRELVAREYERCTQAKHKQWSKVELIALHILLQARA
                     GRQTAVEAAGFDLVHVQAPRSGFFFNPISTALAYIALCIAAPTSDPWFVLRSQLLDHQQ
                     ADGSWRFCTSDVWDTSLIVRAFAGHPTFVQTALQPALDFLQATQNVDGGWPFRSGVESD
                     NDSTGAVMLALHGTMQGERTKDRALAYLARVQMANGLWRTWQFRDDPPVEDVVAHVLSA
                     LDAYRGRHRLAVGTARQWLAEEVERRGVWSASWYRGVPYAVAEIGRALGPDHPLTRRGV
                     DALAARQNDDGGWSPEAGGASTASATGLALQAIVDRHPGRVDRALQYLVDAQRADGTWP
                     GTPDMFGPRPLLSHFITHTQAFVVGGIRAALRRNWPWPVRVAAVPEGAA"
     misc_feature    12436..12449
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.61"
                     /tool="antismash"
     misc_feature    complement(12436..12451)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.0"
                     /tool="antismash"
     misc_feature    complement(12438..12451)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.86"
                     /tool="antismash"
     misc_feature    12439..12452
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.54"
                     /tool="antismash"
     misc_feature    complement(12439..12454)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.0"
                     /tool="antismash"
     misc_feature    complement(12441..12454)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.86"
                     /tool="antismash"
     misc_feature    12442..12455
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.54"
                     /tool="antismash"
     misc_feature    complement(12444..12457)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.19"
                     /tool="antismash"
     misc_feature    complement(12522..12535)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.05"
                     /tool="antismash"
     misc_feature    complement(12587..12607)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 19.81"
                     /tool="antismash"
     misc_feature    12733..12748
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.32"
                     /tool="antismash"
     gene            13713..15806
                     /locus_tag="O0S08_RS34290"
                     /old_locus_tag="O0S08_34290"
     CDS             13713..15806
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1117:
                     sodium/hydrogen exchanger"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013188.5"
                     /locus_tag="O0S08_RS34290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_34290"
                     /product="cation:proton antiporter"
                     /protein_id="WP_269033649.1"
                     /transl_table=11
                     /translation="MAADLVHYVRDLSIILGTAAATGLISQSLRQPPVLGYLIAGMLIG
                     PHVPGIVLGGPDSLEMTQDLSEFGVILLMFSVGLEFSLRKIARIGPGAGLTAVFEIGLM
                     MTLGFLVSALLGWSTIESLFLAGCICSSSTMIAAKAFEERKLRGGFVELTFAILVFDDM
                     TTILVFAVLTAIASGAGLGPGEFALSVGQLFGFLLALLAGGLFVVPRALRAVVRRERDE
                     LTLLAAIAACFGMASLAAMAGYSVALGAFIAGILVSESGEGGRIEPLVLPVRNIFAAIF
                     FVAIGMQIDPLQIVANWPLVLIFTAVVLVGKVLGVSLGAFLSGNGFKASVRAGMSCAHN
                     GEFSFIMASFAISKGILGDFVFPVAVGVSVLTQLTAPMMIGRSESVALALEQRLPAKLQ
                     TFITFYQSWIEQLRSAPRTVSVWSQIRGDAVVLALDAALLWAVLAGSNLVHWWVVTELT
                     ERFTLPPWLVELTWLGGTLLLAAIFLLGVLRRAAALARRLAEIVIPVRGGKLDLGSAPR
                     RVFVVALELALCLVVGLPLVALVQPFLPLSSAPLALLVVVVALMISGWRNIAHLQGHVR
                     AGTELIVEVLAKQSREGDATVQASLDDVQALLPGFPDMTPVRLQDGSAAVGLTLAQINL
                     RVRTGATVLALSRDGAGAEVPSPRDTLRPGDILTLTGSEAAIAVARTLLHEGPAADPVQ
                     VES"
     gene            complement(15916..16749)
                     /locus_tag="O0S08_RS34295"
                     /old_locus_tag="O0S08_34295"
     CDS             complement(15916..16749)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (3-175). E-value: 4.5e-11. Score:
                     34.9. Matches aSDomain:
                     nrpspksdomains_O0S08_RS34295_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020656821.1"
                     /locus_tag="O0S08_RS34295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_34295"
                     /product="oxidoreductase"
                     /protein_id="WP_269033650.1"
                     /transl_table=11
                     /translation="MAKVWFITGASRGLGLEIAEAALAAGDIVVAAVRDPERAAAAMAE
                     HPRRMFVKLDVRDEAQAQAAAAAAVERFGRIDVLVNNAGYGLLGAVEEGAADEVEALFR
                     TNVFGLLAVTRAVLPHMRRQRSGHVLNMSSLGGYASGQGWGLYCATKFAVEGITEALAQ
                     ELAPLGVHATVIEPGFFRTEFLAGGSLGRVKREIADYAATVGTVREFADGHDGEQPGDP
                     KQLAQVMLKVVAAEQPPVRVPVGADAFARVESKNAAVAAELAQWREVAAVRGFAG"
     aSDomain        complement(16225..16740)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_O0S08_RS34295_PKS_KR.1"
                     /evalue="4.50E-11"
                     /label="O0S08_RS34295_PKS_KR.1"
                     /locus_tag="O0S08_RS34295"
                     /protein_end="175"
                     /protein_start="3"
                     /score="34.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VWFITGASRGLGLEIAEAALAAGDIVVAAVRDPERAAAAMAEHPR
                     RMFVKLDVRDEAQAQAAAAAAVERFGRIDVLVNNAGYGLLGAVEEGAADEVEALFRTNV
                     FGLLAVTRAVLPHMRRQRSGHVLNMSSLGGYASGQGWGLYCATKFAVEGITEALAQELA
                     PLGVHATVI"
     CDS_motif       complement(16603..16737)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_O0S08_RS34295_0001"
                     /evalue="1.90E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="O0S08_RS34295"
                     /protein_end="49"
                     /protein_start="4"
                     /score="10.9"
                     /tool="antismash"
                     /translation="WFITGASRGLGLEIAEAALAAGDIVVAAVRDPERAAAAMAEHPRR
                     "
     misc_feature    complement(16857..16871)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.56"
                     /tool="antismash"
     misc_feature    complement(17052..17064)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.46"
                     /tool="antismash"
     gene            17212..18228
                     /locus_tag="O0S08_RS34300"
                     /old_locus_tag="O0S08_34300"
     CDS             17212..18228
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (97-262). E-value: 1.6e-08.
                     Score: 26.6. Matches aSDomain:
                     nrpspksdomains_O0S08_RS34300_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010796620.1"
                     /locus_tag="O0S08_RS34300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_34300"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_269033651.1"
                     /sec_met_domain="adh_short (E-value: 1.2e-30, bitscore:
                     106.0, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 6.3e-30, bitscore:
                     104.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPKDSDRITRRQMVGTMGVGLAAATVAGSAPATAAPAGAGESAT
                     TARLQNPTTQYPRPPFPAQQQPWPGLASKMTPRPDHGEMSYRGSGRLAGRKALLTGGDS
                     GIGRAAAIAFAREGADVAINYLPVEESDAQEVIALIQAEGRKAVAVPGDIRDEAFCKQL
                     VAAAVEQLGGLDILVNNAARQQQRKSILELTTEDFDATFKTNVYAMFWITKAALPHLSA
                     GASIINTASVQAVDPSAHLLDYAQTKAAIVAFSKSLAKQLAPQGIRVNAIAPGPFWTPL
                     QPSGGQPPDKLVNFGGDTPLGRPGQPAEIAPLYVLLASEESSYCTGQVLGASGGTGK"
     misc_feature    complement(17213..17227)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.96"
                     /tool="antismash"
     aSDomain        17503..17997
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_O0S08_RS34300_PKS_KR.1"
                     /evalue="1.60E-08"
                     /label="O0S08_RS34300_PKS_KR.1"
                     /locus_tag="O0S08_RS34300"
                     /protein_end="262"
                     /protein_start="97"
                     /score="26.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="LLTGGDSGIGRAAAIAFAREGADVAINYLPVEESDAQEVIALIQA
                     EGRKAVAVPGDIRDEAFCKQLVAAAVEQLGGLDILVNNAARQQQRKSILELTTEDFDAT
                     FKTNVYAMFWITKAALPHLSAGASIINTASVQAVDPSAHLLDYAQTKAAIVAFSKSLAK
                     QL"
     misc_feature    complement(18229..18242)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.67"
                     /tool="antismash"
     misc_feature    complement(18561..18575)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.76"
                     /tool="antismash"
     misc_feature    complement(18958..18971)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.03"
                     /tool="antismash"
     gene            19082..20383
                     /locus_tag="O0S08_RS34305"
                     /old_locus_tag="O0S08_34305"
     CDS             19082..20383
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012242.5"
                     /locus_tag="O0S08_RS34305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_34305"
                     /product="Hsp70 family protein"
                     /protein_id="WP_269033652.1"
                     /transl_table=11
                     /translation="MPTSAPRVGIDFGTSSSALALVDAEGRVRFAQLPTLGVLGPSWRT
                     LLFFDPDDQEVQQPLQYTAGGEGIEAYLECMGEGRLLQSFKTHLTTESMGRTQVAHHAI
                     GLDDMIALFLQRLRERAEQHLGVALDAATIGRPVHFAGGTTPEADALAAERLLAAARRA
                     GFRDARLELEPVGAAHHYERTLTRPELALVADFGAGTTDFCLMRMGPTGHGSTRARDII
                     GTGGVGAAGDDLDAALIEHLVCPALGKGDTYVEMGVERQIPGSYYYKLARWHHLPFLAG
                     ARVRAELERLRRGARHPERIAKLMHIIATNGAFHLHKAVERTKVELSGRKQATFDFSDG
                     EIDIHAAVSRRDFERWIAPITASIAACLDDTLARAGVTAGEVDCVFMTGGTAFVPVVRA
                     LFEARFGAAKLRSGDELMSIASGLALRAAAPDGG"
     misc_feature    complement(20434..20447)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.43"
                     /tool="antismash"
ORIGIN
        1 ccgcgaggcc gcgtcgcacg agacggtgat gcaatgaaga aaccatggca atactcctta
       61 ttcctggtaa gtgccccgat atcgccgggg ccgagtccat ccaatgtgcg gcgcgtcgac
      121 ccggaccgga tcaccgccgc cgtcgcatga cgagacggca cccggcgaaa ccccgtccac
      181 gcgcctccgg cccgactcgg cgccgcccgt ggcaaaccgc acgcccatcg ccagcacggc
      241 atgaaaccgc gggtccgatc gcggtaggtg cggtggaccg cgcgcctgaa ctccggtcag
      301 gcacacgctc accgctcatt gcacaatgga cggtgaatca cccccgcgac gagacggctc
      361 attcgaatcg accaggcgcg gcgccttcga ggtcgctctc ccgacgccct tcgccgccgc
      421 gcgcgaggac cccggccgcg cctctcggcc acaatggccg agaggacatg tcccataaaa
      481 cagctagttc gccgggacca cggtgacggt gttggcgagc tggaccagca cggccacgct
      541 gtcgtccgcc tcctggtaga cgtaggcgcg cgcgtacgtc cccggggtga gcagcgggag
      601 gtcgaagatc gcctgcacgt cgccgtcggc ctcggcgtcg aagccgatgg tgtacatccc
      661 cgccggcacg tcgatcgcct cgggcgtctc gccgaagccg aagtcgtcga cgagctgggt
      721 gccgaacgtc gtgccgccgt ccagcaggac gtagatgtcg ccgcgcgtca cctcgggggc
      781 cacgtgcgtg atcgggacgc ggatgtccga ctgcgccagc cccgaggcgt cgtccgcgag
      841 cacgagcgcg ccgatcgagg cgaggtcgtc gtacgcgacg acagtgtacg cgcgcccggg
      901 gaggaggctg gcctcggcgt cgacgacggc ggtctcgacc ggcatgcccg cggccgtgac
      961 ggcgagcccg agcgtcccgc tcggcaccgt gaggaacgtc gactggtcct tgaacgcgag
     1021 gtcggtgacg acgcgctcgc cgcccgcgta gacgtcgacg ttcggcgcgt cgcgcgagag
     1081 gtgcagcacc cgcacctgcg actcgctggc gtcgatccgc gccgtcgtgg ccccgtcgag
     1141 ctgcgccagg acgaacggct ggccggcgtc ctcctgcgtc acgtagacgt tggcgagcgt
     1201 cccgccgggc agctccggca gctcgaagta gaggtcgggc ttggcgtcgt cgttcacgtc
     1261 cacgccgagc gtataggccc ccggcggcag atcgagcggc tcggccgcgg cgccgaagtc
     1321 gaggtcggag aggatgccgg tcgcgctgcc gtcggccgcg acctggtaca cgtcgaccgg
     1381 gccgatgtcc ggtgcgccgt ggatggcccg cacccggatc tcgctgtcct cgagcccctc
     1441 gcggtcgtcc ttgaagacca gcgcgccgag ctcggcgacc cgaccgatcg ccgccgccgt
     1501 gtaagaagcc ccctcctcga aggtcagctc ggcgctgagc accgacgtcg cgaccgtgcc
     1561 gtcggtcgtg atgtcgatcg tccccgacgg caccgagatg ctcgcatagt cggtgctcgc
     1621 agggaacgcg atctcaccga actcggccgg cgcggcgccg gcgaacagcg gctggacggc
     1681 cggcgcgtcc gggctcagat ggaccacgcg gagccgctgc tgcgccgcgt cgatccgcgt
     1741 cgtaccgtcc gggagctgcg cgaggaggaa cgcggcgcct gcgtcgtcga cggtcgcgaa
     1801 gacgttgacg acgacgcccg ccggcagact ggggatcgag tagagcaggt cggggttgcc
     1861 gtcgtcgtcg acgtcgaggc cggcgacgaa cgggtccgtc ggcaggtcga cgggctcggc
     1921 ggaggtgccg tagcgcaagt tctctgcgat cagatcgggc gagccgctcg cgccgatggc
     1981 atatacgtcg acgttgccga cgccggcgcc ggtgtggacc acccggaccc gcacgtggcc
     2041 gctggcgagc ccctgggtgc tgtcctcgac gacgctgacc tgcacctcgg cgagctcgcc
     2101 gaacgcgaag gcggtgtagc gccggccctc ctcgagcagc gcctcggcga gcgtcgccac
     2161 cgcggcgccg gcacccgtac cggcggccgc cacctcgatg gagtgctggc cgaccccgac
     2221 gttcgccggc tggctgccct gcgtgaacgc gaggttcgtg accagagtgt cctgcccgtc
     2281 gacgaacgca tcgatgctgg gcgcgtccgg gctcaaatgc acgacccgca cctcggcccc
     2341 ggtctcgttc gcgggatcgc gggtgtcgtt cccgcagccg agcagagcga gggtgattgc
     2401 aaacacggag agagcgcgcg tgggccccat cgtcgtgagt ctctttctaa acatgcgagc
     2461 agcatggccg agcccgggcg cggcggtcaa tgcgagcccg cggcgagggc gatgcgtcgc
     2521 ccgaattcgg cggtacgaac ggcgcagggc cccggatcat gacaatcaga aggcgcgatc
     2581 gcgggcgcgg agacggaatc gcgcgagcgc gccgtcgtgg ccgccgactg gacgcagaac
     2641 gtcgattcat ccgagcacgg ccggccggct gcgcggggac gtcacgcgaa acatcattcg
     2701 tgaatgggcc caagtgcgac gaatcgcgcg acaccccgct cgtccctcgc gtcgccctcg
     2761 cctttcgtcg ccgacaggga gcgacgaggc gcgcccctgc tcggcggatc ctcgggaagc
     2821 gctcgccgga cagcgcttcg ccggccttca tggtggccaa caacctggtg aggccgtccg
     2881 tcatgcccgc gtcgtacgac ctctgcggat cgaaccgcgc gtcggcgtcc atccgcgagc
     2941 gcctcggcga cctccgcggc ggagagcgcc cggggcacct tcaaaaagcc ctccgcccgg
     3001 tatcgttcga cttcaagctc gttcagaacc atgggaatcc tcgcaggcga atcctcgcgg
     3061 tcgattcagg cccgaaacgc gtcggcgtgc tcgcgcgccc aggcggcgaa ggtgcgggcg
     3121 ggacgtccgg tcacctgctc gatggtgggg acgatccggg ccgcctctgc cggagggtcg
     3181 cgcgccagcc ggatcccgaa ctcgacgtag tcctccgaat agccatagga ccggaggcgc
     3241 tcgcgctccc gggcctcgtc gagcgcctcg aaggcgatcg gccggcccac cgccgcggcg
     3301 atccgcgcca cgcgttcggc aggcgtcagc gcctcggggc cgctcagcga atagcgccgg
     3361 ccctcgtggc cgtcctgcgt cagcgccgtg gccgccaccg ccgcgatgtc cgcctcgtgc
     3421 acgaccgcgc tgggccaggc ggcgagcatg cgcacgacgc cgccttgccg gatgctctgc
     3481 gcccactcga gcgcgttggc catgaactcg accggctcga gccgggtcca gccgatcgcg
     3541 ctgccctcga gcgcccgctc gacggaggtc tcgtcccagc cgcccaggac agtggcccgg
     3601 cggacgcccg agcgctcggc gaggcggacg agctcgtcgc cgtcgaccag cgactcgccc
     3661 tcaccggcga aggtgatcag gtggaccgcg ctcacccccg cgaacgcgcg cgcgagcgag
     3721 gccacgtccg cgaggtcgcc cgcgacgacc tcgacgtcgg gcgggaggtc ggcctgcgcg
     3781 gggcgccgcg acagcgcgcg gacgcgatgg ccggcggcga cgagctgatg gacgaggggc
     3841 cgaccgacgg tcccggtcgc gccggtcacc aggatcgtgg cggggtgctg caattgcgtg
     3901 gtcatggcaa aactccgtgc gagcttcggc cgcccgtcgg gcggcgcccg caggtgatac
     3961 cgccgcgctc ctgacagaac ctgtcagcag cgcgccgggc ctcgcacgga gcccctcagg
     4021 cgggcacgac ggcggcgatc cgcgccggca ggcgcacgcg gatcgtcgag ccgacgccga
     4081 actcgctgtc gacgaagatc tcgccgccca tcatgcggca caggcggcgg ctgatggaca
     4141 ggcccagccc ggtgccgccg tagcgccgcg tgacgtcggc gtcgacctgc gagaagccgg
     4201 cgaacaggcg ctgcatctgc gccgtggtca tgccgatccc ggtgtcgcgg atcgtgaact
     4261 cgacgcagtc gacgccgggg agcggcatgg tctcaccggc agtgtcgaag tcgcggctgc
     4321 acgcctgccg gcgctcgacc agcagctcga tgctcccgcg cgaggtgaac ttgcaggcgt
     4381 tgccgagcag gttgagcagc acctggcgca ggcgcgtcgg gtccgacacc atctcgccca
     4441 ccccgttgca gcggcagcaa tagctgttct cgttcctgcc gacgagcggg cggatcgcct
     4501 cgttgatctc gacgatcagg gcctcgaggt cgaaggcgtg cgtcaccagg tcgagcttgc
     4561 ccgcctcgat cttgctgagg tcgaggatgt cgctgacgag cgacaagagg tgcgtgccgg
     4621 cggagtggat ccgccggacg tcgtcggcga gctcctggtc gtggttctcg accagctgct
     4681 cgtggaggag ctcgctgtag ccgaggatcg cgttgagcgg ggtgcggaac tcgtggctga
     4741 cgctggccag gaacatgctc ttggcgtggc tggccgcggt cgcctggttg cgcgcgtgct
     4801 gcagctcggc gttgagctcg cgcagcgcct tgagcgagcg gttgcgctcg acggcgtagc
     4861 ggatcgatcg ctcgagctgg cgcgggccga actcaccctt gaccaggtaa tcgaccgcgc
     4921 cggccttcat cgcctcgacg tcgagcgagc gctcggactg gccggtcagc aggacgatcg
     4981 gggtcgtgca gccgcgcgcg accacctcgc gcagcagctc gagcccggtc ttctcgccca
     5041 ggcggtagtc gagcaggcac aggtcgggcg cgcccgtgaa cagcgcctcg acgccgtcct
     5101 cgtagcaatc ggcccactgc aggacgtagg tcccctcgcc gatctcctcg agcagctcgg
     5161 aggtcagcag gtagtcgtcc cgatcatctt cgatcagcag caccgagacc gatgtgtgca
     5221 ccgcatgaac ctccgccgcc cccgtcacga gggccgatgc tcgcccccgg ccgcccaccg
     5281 gtccgggacc cacacgcgta gcaccgaccg ccgcgcgccc tcggtctcga cgaacagctc
     5341 gccgccgagc aatcgacaca cccgccgact gcccgagatg cccgactccg tccacgcgcc
     5401 ccgcggcgcc acgccggcgt cggcctgcgg gatgctggcg aacagcagct cgagctgcgc
     5461 cggcgtcatc cacaggccgc tcgcgcggat cgccagctcc acgccgtcga cgccgccctc
     5521 cgagcgacgc gtcaccgaca ggtgaatacg gccgcggcgc gcgaacttgc aggtgttcgc
     5581 gagcagagtg agcaggaccc gccgcaggtg cgcggggtcc gtctcgatcg cgccgatgtc
     5641 gtccgcacag ctgacctcga gggtgttgtc gttgtgcccg accagcgggc ggaccgccgc
     5701 caccacctcc tggatgaacg gcgccagcgc cagcgacctc ggctggacca ccggcgcctc
     5761 gctcgcgctg gggctcatgt cgagcacgtc cgtcagcagc cgctccagcg tccggcaggc
     5821 ctcgcggacc tcgcgcgcgt agccctccgc gaccgcatca cgcccggcga agcgggcctc
     5881 gagggcgtcg ttgcaggcga cgatggtccc gagcgactcg cggcaggtct ggctcaccgc
     5941 ggtgaggacg tcgttcttgg cctggttggc gcgcaccgcc tggtcgcggg tcagctcgag
     6001 ctcgcggttc agcagccgca gcgccgacag cgagcgcgcc cgctcgagcg cgtagcggat
     6061 cgaccgctcg agcaggtccg cgcggatccg gctcttcacc aggtagtcgg ccgcccccag
     6121 gcgcgtggcc tcgacgtcga gccggtgctc gtcctgcccg gtgaggaaga tgatcggcac
     6181 ctcgaccccg gccgtcgcgc tctgcgccag cagctccatc ccggtccgct cgcccagcgc
     6241 gtagtcgagg agacagacgt cgaacgaccc gtcgacgagg cgcgagagcc cctcctcgaa
     6301 gctctgcgcc cacgtgaggt cgcatttcgg ttcgtcgatc tccgagagca gcgcctgggt
     6361 catgatgaag tcgtcctcgt cgtcctcgac gagcagcacc gaaattcgtc gcctcatagt
     6421 cgccggcctc gtcgcccaga ctaccctcct tccgccgacc gcgggcgcgg cccgggccgg
     6481 cggacggctg tccgcgttgc cgctcgcctg ccggcggggc ggccgctacg aggaggggac
     6541 ctcgacgatc tcgaaccagt atgcgccgag gatcttcatg atgccgacca gcgagtcgaa
     6601 cgtgaccggc ttgatgatga acgagttcac gccgaggtcg tacgtgcggt agatgtcttc
     6661 ctcggctttg gacgtggtca ggacgaccac cgggatccgg cgcagctccg cgtcgccctt
     6721 gatcaccttg agcgcctcgc ggccgtccat gcgcggcatg ttgaggtcga gcaggatcat
     6781 gtcgggccgc gggggatcgc tgccggcgta ggcgttccgc ctgtacaggt agtcgagcag
     6841 gtcctcgccg tcatcgacga agcggatgtc gttgaccagg cgactctcgc ggagcgcctc
     6901 ctcggccagc atgcgatcct cggggtcgtc gtcggcgatg aggatggtga tcggtcgacg
     6961 gcttctcacg tccgctggct cctttcgggc tgccggatcg gcagcaggat cgtgaaggtg
     7021 gtcccctccc ccggcacgct cgcgaccttg atgtagccgc ggtgctgctc gacgatcttg
     7081 cgacacaccg ccaggccgac gcccgtgccc tcgtacttgc cgcggccgtg gaggcgctcg
     7141 aagatgctga agatccggtc gtggtggcgc ggctcgatgc cgatgccgtt gtcggtgacg
     7201 tggatcttca ccatctccgg gtcgtcgggc ccgcgctcgg ccggcggcac cggctcccag
     7261 gtgacctgga ccaccggctt cacgtcgggc cgcgtgaact tcagcgcgtt gccgatcaag
     7321 ttctgcagca gctgccgcat gtgcaccggg tcggcctcga tcgtcggcag ctcgccgagc
     7381 ttgacctcgg cctcgttctc ctcgatgcgc acctcgaggt cggacagcac gctcttggcg
     7441 atcttcgtca ggttgacctt cgcgtaggcc tgctccttgg ccgagatccg cgagaacatc
     7501 agcaggtcgt tgatcaggtc ctgcatccgc ttggcggcgc tgcggatccg ctcgaggtaa
     7561 tcgcggccgg tgtcggccag cgcctcctcg aacttgtcgc gcaggcggtc gctgaacgcc
     7621 tggatcttgc gcagcggctc ctgcaggtcg tgcgacgcga ccgaggcgaa ccgctcgagc
     7681 tcgcggttgc tgcgctcgag ctgctgcatg tagtcgcgca gctgctgctc cgcgtagcgc
     7741 ttggcctcct cggcctgccg ctcctgggtg acgttgcggg tgatcagcac gacgccgatc
     7801 gagcggtcgc cctccatgat cggaccgagg cggctggcgt agttctcctt gcggccgtcg
     7861 gggtacatcg cgaccgtctc gtacgcgatg agcttgcccg tctcgcgcac ctcgtcgtag
     7921 cgggcgcgca tcggctcctg ctcctccggc gcggcgaacg ccagcatcgg cgtgccgatc
     7981 gtctgggcca cggtgaggcc cggcgggacc cgattcacgc cgttgagcac gccgtgctcg
     8041 tcggtcgtga agacgatgtc gtgcatcgtc tcgaacaccg ccgccagccg gcgccgggcg
     8101 tcgtcccgct ggtgccgcag ctcgtcgagg tcggtgagct cgcggaccgc gatcaccagc
     8161 agctcgagcg aacggtcgcg gccgcaccgc agcgtcaccg cgcgatagct ggccccggcg
     8221 cagcgcagtc ggcacgtcag ctcgacggtg atcccgtcct cgttcgcccg cttcagcccg
     8281 gtcgacaccc gctcccggtc gtcgggatgg acctgatcgg ccagcgattg gccgagcagc
     8341 tgggcgctcg tgctctcgag aaattgcgcc gcggcttgat tgaccacggc gagccggccc
     8401 tccctatcaa ggcagatgaa cggctcgtgg gcgagagcaa acagcgcagg atagtcgggc
     8461 aactaatccc cctcgggttc cgtcctctat accagcgttc cgcggggccg agaagcgccg
     8521 aaccgacgta ctcgagtgcg gtgggtcgca gcgcctcagc gcgcttgcga cgaccctgac
     8581 ctccgccggc cgcgcggctc agagcgctca gcgacccgcg ccgcgcaagc gcgcgtagat
     8641 cggacgatcg gggtgcaccg tcgcggtcgg gcggattccg acgtgctgat ccggcagcac
     8701 gtcgattcga aatcgggaca ggatcaggac cagcgcggtg ctcagctcgt aaatcgcgta
     8761 acgcttgccg atgcacgcgc gcgcccccgc actgaatggg atgtgtgcat accggtggcg
     8821 agcccgcacc ttctccggcg cgaatcgttc agggcggaaa gcctccggct cgtcccagaa
     8881 cgcggggtga tggtggcaga aatacgccga gaacatgatg aagctgcccg ccgggatccg
     8941 ccgcgcgagc aggacgtcgt cctcgcgcac ctcccgagtc tgcgcccata tcggcggccg
     9001 cagacgcatg acctcgtcga agaccattcg cgtgtacgtg agacgatcga ggtcctcgat
     9061 ggtgggcacg cccgtcagcc cgagccccgc gatctcttcg cacaccttcg cgtacacgtc
     9121 cggatgctgg ccgagcagcc agaacgtcca ggtgaggatc agcgccgtcg tctcgtggcc
     9181 ggcgacgtac tgcgtgacga tctcgtcgcg cagctgccgg tcgctcatgc cgtcgccggt
     9241 gccgtcgtcg cgcgcctcca tcagcagccg cagcagcgtc ggctgcgact cgggcccggc
     9301 cttccgcgcg tgaccgatga tgtcgtagac gatgccgtcg agggtccgca gcgcccgacg
     9361 aaagcgcaga ttcgccggcg tcggcaccga cagcggcagc gccatcgccc cccggttcat
     9421 ccgctgtccg gcgatctcga ggctctcggt gaccgcccgc gacgaggccc cctcgcgatc
     9481 gctgaggtcc atgccgaaga gggtaaagcc gacgatgcgc tgggtgaggt gcatgatctc
     9541 cgcgtgcaga tcgagcaccg cgtcgtcgcg ccggcgcgcc tcccactcga cgagcatgtc
     9601 gtcgacgcag cgcgccatca ccggcaccat tcgccgcagg ttgtccatgt ggaacgccgg
     9661 ctgggtcagc ttgcgctggc ggacccagaa gtcgccggtg ctggtgacga ggccgttgcc
     9721 gagcagcgga cggatcgggt cgtagccctt gcccttgtag taattgtcga cccgcgtgtg
     9781 gaggatccgc tcgatcgcgt cggggtgggc ggtgaagatg atccggctgc gaccgccggt
     9841 ggggatctgg aagaaatcgc cgtactctcg ccagcagcgc tcgacgtact cgaagatgcc
     9901 ttcgcgcagg atggcaggga gggcgccgac cagcggatag ccggcaggcc cgggcaaccg
     9961 gagcagctgc tccgctcgtg gatggaggag tgtattcatg tcacctcgct aggtccgtct
    10021 cgaagcggag cggaccggtg gcgtaccatc gatgaatgca acgaacgagt cgggacagcg
    10081 tggccgcgaa cggatcgcgg gccccgaggc gatcgaggtt gtgctgcaag agccgctcgt
    10141 agccctgccg ctgcgcctcg acgaacgcgc gcgcctgcgc gggcgagagg tcgcgctcca
    10201 gcaggaggac cgcgttcgac acgcgcccgg cgtgcccctc gcggcgctcc ttctcggcac
    10261 tctggaggtc gttgagcagc cgctgcgaga ggtagaggta gcgctcgacg ttggcgatcc
    10321 gcgggtcgtc gtgccgccgc ggccgatcga gccggcgcac cagataggcg gcggtgagga
    10381 tgctcggcaa ggtggtgctg tgcgcgcccg tctcgatgca ctcgaccagc gagcgcgcct
    10441 cggcgtcgcg cgacatccgc tcctcggcga acatggcccg gaacaccttg gccgagccga
    10501 cgcggaacca tcggtgctcg tcgcggctgc ccgcgagcgg cgcgagcagg tcgcacaggc
    10561 gctgaaagaa gcggacctcc ggcgtgtcgg cgccgccgcg cggcggctcg tcctcgccgt
    10621 acgcgatcag cgtgtcccag tcgaccggcg tctgctgctc gcgcaggaac ttgtcgctgc
    10681 gatcgtcgaa ccagaaccag taggcgctga cgagggcgat gaggaacacc tcctcgcggc
    10741 cgtcgacctg ggggtcgacg caggcctcgg cgacgtacaa gccgtcggcc gcgtggtgca
    10801 ctgcgaagtc ctcgaagtcg gcggcccacg ccatgatgcg ggccagcaag acctggtcga
    10861 cggcggcggc gatccggctc atgtcacgcg gctccttccg gcactgcggc gacgcggacc
    10921 ggccacggcc agttgcggcg cagcgccgcc cggatcccgc cgaccacgaa ggcctgggtg
    10981 tgggtgatga agtggctgag cagcggccgc ggtccgaaca tgtccggagt gccaggccag
    11041 gtcccgtcgg cccgctgggc gtcgaccagg tattgcaagg cccgatcgac gcgccccggg
    11101 tggcgatcga cgatcgcctg cagcgccaga ccggtcgcgc tcgcagtgct cgccccgccg
    11161 gcctccggcg accagccgcc gtcgtcgttc tgccgcgccg ccagggcgtc gacgccgcgg
    11221 cgcgtcagcg ggtggtccgg cccgagcgcg cgcccgatct ccgccaccgc gtacggcacc
    11281 ccgcggtacc agctggccga ccacacgccg cgccgctcga cctcctccgc caaccattgc
    11341 cgcgccgtcc ccaccgcgag ccggtggcgc ccgcgatacg cgtcgagcgc cgacaacacg
    11401 tgcgcgacga cgtcctccac gggcggatcg tcgcggaatt gccaggtccg ccacaggccg
    11461 ttcgccatct gcacccgcgc gaggtaagcc agcgcccggt ccttcgtgcg ctcgccctgc
    11521 atggtgccgt gcagcgccag catcaccgcg ccggtgctgt cgttgtcgga ttcgacgccc
    11581 gagcggaagg gccacccgcc gtcgacgttc tgcgtcgcct gcaagaagtc cagcgccggc
    11641 tgcagcgcag tctgcacgaa tgtggggtgc ccggcgaaag cgcggacgat cagcgaggtg
    11701 tcccagacgt cgctggtaca aaagcgccag ctgccgtcgg cctgttgatg gtcgagcagc
    11761 tgcgatcgaa gcacgaacca cgggtcggag gtcggcgccg cgatgcacag ggcgatgtag
    11821 gccagggccg tgctgatcgg gttgaagaag aagccggagc gcggcgcctg cacgtgcacc
    11881 aggtcgaagc ccgccgcctc gaccgcggtc tgccgaccgg cgcgcgcctg cagcagaatg
    11941 tggagggcga tcagctcgac cttgctccac tgcttgtgct tggcctgcgt gcagcgctcg
    12001 tactcccgcg cgaccagctc ccgcaattcg tcctcggacc ggcgcgcccg cacctcgagc
    12061 ccggcgtgca gggccagcgt gtgcagcagc atcgtccggc tggccagcac cggcccgtcg
    12121 agctcgggcg cggtcaggtc gaccaccccg ccggcgccga cgaggatccg ccgcagcgta
    12181 tcctccaata gaaaggacac cgggtgatga tcctgcggcg ccgccgattc gacccacgcc
    12241 cgcgcccgcg ccaccgcccg ccgatcgagc cgacccggcg tgtgggccag ggcgtacccc
    12301 gccagcgcgg tctcgaagat ccgcccgtcc ggcgccacct cccacgatcc gtcgggccgc
    12361 tgcagcgaga tgcaatgctc gaccgccagg cccaggcacg ccgccacccg ctcggccagc
    12421 gggtgaacga gccgcgatga tgatgatgat aataacccct cgccgttccg ttcggcggaa
    12481 ggagattcgt gccgaatggc gctgccgcga ggactccgcg cttttattgt cacgtgattg
    12541 tcctatcgca tgggtggttc ggagctgtca agcaattcgc ctcagtcgtc gagcgagtgc
    12601 aatgtttgtt gcgtaacgag tccaaacgct atgcttcact ccagcgcagc ggcacggcga
    12661 gtcgcatcga cccgccccac cctccgcaca ctcttgatag tgatccaaat gtcgccacgg
    12721 atcacgtccc gtcgaacaat tttttgtcgt cccacgaata cagcgccaac gccgcgcgag
    12781 cagagagatt cgcggtcgcc cgccacgggc gtgaaccatg tcctatgaac aatgttcgaa
    12841 tgacgttcat ctgcaccgcg ccgcgatccg gcgattgctc ggcgaggcct cgacgcggcg
    12901 gcgctcgccc cgcgatggca gatgtcggct gacgtcattc atgatgccaa tccccgcggc
    12961 tgcacctccg tctacaggga ctgcccgatc ctcgcccgcg agtcgaatct cgccgcaagc
    13021 ctcgtgctcc atgtagaatg aatcgtcggg catccagcgg agcctgatgc cgactcgggt
    13081 tcacccgcga gaacctttgt cgagcccccg cccgtcaccc cgtcagacct gccgcagacc
    13141 gccctgcgag gcccgtgaaa atcgcgcact ttgcgggtag tcgcggtgca tccaggtcgc
    13201 gaaccactcg ccggcggtcc gcgatcgtac gccgttcaca acggcggaag cattgatcaa
    13261 tcgtactgtg cgcattcacc gtcggagggc cggcccggcc ctgaccgagt ggggagccgt
    13321 tcgctgcttc cgcacggtga gatctgggag ccggcgaatc gacggcggct ccccttccga
    13381 tccgacccgg acctccgagg gggacgccgg gtgacatcga gggagtcgtc aatcagggac
    13441 tgcgtcgagc cggaggagtc tgccgaggat cggcgcagac ccgggcggcg gggcagactg
    13501 cgagtacgcc gtcgcaggtc cgctcgcggg gaggtgcgcc ggcgagatcg caaccgcgtc
    13561 cgtctgtcgc gcccgcgacg gcgtcgcgcg ccggtccgcg tgcgagcggc ggaaccaacg
    13621 gcgccccgac aagcttgcac gccgcatgac atcttggaca tgtgctgctc gctgcgggcg
    13681 gcggtcggca cgcgcgtgta tcgtcacacg ccatggcggc cgacctcgtg cactacgtcc
    13741 gtgatctcag catcatcctc ggcacggccg ccgcgacggg gctgatctcc cagtctctgc
    13801 gacaaccgcc ggtgctcggc tacctgatcg ccggaatgct catcggcccg cacgtgccgg
    13861 gcatcgtgct cggcgggccc gacagcctcg agatgaccca ggacctgtcg gagttcgggg
    13921 tcatcctgct gatgttcagc gtcgggctcg agttcagcct gcgaaagatc gcccgcatcg
    13981 gcccgggcgc gggcctgacc gcggtgttcg agatcgggct gatgatgact ctggggtttt
    14041 tggtcagcgc gctgctcggc tggagcacga tcgagagcct gttcctcgcc ggttgcatct
    14101 gcagctcgtc gaccatgatc gccgccaagg ccttcgagga gcggaagctc cgcggcgggt
    14161 tcgtcgagct gacgttcgcc atcctggtgt tcgacgacat gacgaccatc ctggtgttcg
    14221 cggtgctgac cgcgatcgcg tccggggcag gcctggggcc gggggagttc gcgctgtcgg
    14281 tcggccagct gttcggcttc ttgctcgccc tgctcgccgg cggcctgttc gtggtgccgc
    14341 gcgcgctgcg ggcggtggtc cgacgcgagc gcgacgagct gacgctgctc gccgcgatcg
    14401 cggcctgctt cgggatggcg tcgctggcgg cgatggccgg ctactcggtg gcgctggggg
    14461 ccttcatcgc cgggatcctg gtgtcggagt cgggcgaggg cgggcggatc gagccgctgg
    14521 tgctgccggt ccgcaacatc ttcgcggcga tcttcttcgt cgccatcggc atgcagatcg
    14581 atccgctgca gatcgtcgcc aactggccgc tggtgctgat cttcaccgcg gtggtgctgg
    14641 tcggcaaggt cctcggcgtg tccctcggcg cgttcctgtc gggcaacggc ttcaaggcgt
    14701 cggtgcgcgc cggcatgagc tgcgcgcaca acggcgagtt ctcgttcatc atggcctcgt
    14761 tcgccatctc gaaggggatc ctcggcgact tcgtgttccc ggtggccgtc ggggtgtcgg
    14821 tgctgacgca gctgaccgcg ccgatgatga tcggccgctc ggagtcggtg gcgctcgcgc
    14881 tcgagcagcg gctgccggcg aagctgcaga cgttcatcac gttctaccag tcgtggatcg
    14941 agcaattgcg ctcggcgccc cgcacagtct cggtgtggtc gcagatccgc ggcgacgcgg
    15001 tggtgctggc gctcgacgcg gcgctgctgt gggccgtgct cgccggctcg aacctggtcc
    15061 actggtgggt cgtcaccgag ctcaccgagc ggttcacgct gccgccgtgg ctggtcgagt
    15121 tgacgtggct cggcggcacg ctgctgctcg cggcgatctt cctgctcggc gtgctccggc
    15181 gcgcggcggc gctggcccgc aggctggccg agatcgtgat cccggtccgc ggcggcaagc
    15241 tcgacctcgg ctccgcgccg cgccgcgtgt tcgtggtggc gctcgagctg gcgctctgcc
    15301 tggtggtcgg tctgccgctg gtcgcgctgg tccagccgtt cctgccgctg agctcggcgc
    15361 cgctggcgtt gctggtggtg gtcgtcgccc tgatgatcag cgggtggcga aacatcgcgc
    15421 acctgcaggg gcacgtgcgt gccggcaccg agctgatcgt cgaggtgctg gcgaagcaga
    15481 gccgcgaggg cgacgcgacg gtccaggcct cgctcgacga cgtccaggcg ttgctgccgg
    15541 ggttcccgga catgactccg gtgcggctgc aggacgggag cgcggcggtc ggcctgaccc
    15601 tggcgcagat caacctgcgc gtgcgcaccg gggcgacggt gctggcgctc agccgcgacg
    15661 gcgccggcgc cgaggtgccg tccccgcgag acacgctgcg cccgggcgac atcctgacgt
    15721 tgacgggctc ggaggcggcg atcgccgtgg cgaggacgct gctccacgag ggcccggcgg
    15781 ccgaccccgt gcaggtcgaa tcataggact ctttacaagt cggcgtcgcg gcgcttcggc
    15841 gcgcgattcc tatgagggaa tcgccgtggc gagccgtacc gccgaatgtc gacagtccga
    15901 cacgaccggc gcagctcacc cggcgaagcc tcgcaccgcg gcgacctcgc gccactgcgc
    15961 cagctcggcg gccacggcgg cgttcttgct ctcgacgcgg gcgaaggcgt cggcgccgac
    16021 cggcacgcgc acgggcggct gctcggccgc gaccaccttc aacatcacct gcgcgagctg
    16081 cttcgggtcg ccgggctgct cgccgtcgtg gccgtcggcg aactcccgca ctgtgcccac
    16141 ggtcgcggcg tagtcggcga tctcgcgctt cacccggccg agcgagccgc cggcgaggaa
    16201 ctcggtgcgg aagaagccgg gctcgatgac ggtggcgtga acgccgagcg gcgcgagctc
    16261 ctgcgcgagg gcctcggtga tgccctcgac cgcgaacttg gtggcgcaat acaggcccca
    16321 accctggccc gaggcgtagc cgccgagcga ggacatgttg agcacgtggc ccgaacgctg
    16381 gcgtcgcatg tgcggcagga ctgcgcgcgt cactgccagc aggccgaaca cgttggtgcg
    16441 gaacagcgcc tcgacctcgt cggcggcgcc ttcttcgacg gcgccgagga ggccgtagcc
    16501 ggcgttgttg accagcacgt cgatgcgacc gaagcgctcg accgcggccg cggcggccgc
    16561 ctgcgcctgc gcctcgtcgc gcacgtcgag cttgacgaac atccgccgcg ggtgctcggc
    16621 catcgccgcg gccgcccgct ccgggtcgcg cacggccgcc acgacgatgt cgccggccgc
    16681 cagcgccgcc tcggcgatct ccagcccaag tccccgcgaa gccccagtga tgaaccaaac
    16741 tttcgccatg atcctgctcc tctttgcggc cggcgcccgc cccgtgcggg cgcctcgttg
    16801 gccgctcacg tcgaggaata tgggggcttc ccgcgtgaag aaaaatgggc ttatcattct
    16861 cggactgtga atcaaggctt cacaatcgat tcgaccaatc cggcccgccc agcgcacgag
    16921 ctgtcgacat cggcggtgcc cccgagcgtc ctcctggtgg gtcgcgcgac tgttctgccg
    16981 ctggaccggg cgggtctggt cgggactctc gagcaaggtc gtgcagcagt ggagaccgcg
    17041 gccgtgcgct cgtgacagcg gcgcccagcc gccgccgcgc cgccgtctgc gccgcacgct
    17101 gcacgccgca cgctcggccg acccggccgt cgtgccgcga gccgccggcg ttcgcctctg
    17161 ccgcgaactg gcaccgcgag ccgacgggtc catccttgcg cgcggagacg catgaaaccg
    17221 aaggacagcg acaggatcac ccggcgtcaa atggtcggca cgatgggcgt cgggctcgcg
    17281 gcggccaccg tcgctggctc ggcccctgct accgccgcgc ccgcgggcgc cggcgaatcc
    17341 gcgacgacgg cccgactgca gaacccgacc acgcagtacc cgcgcccgcc gttcccggcg
    17401 cagcagcagc cgtggccagg gttggccagc aaaatgacgc cacggccgga ccacggcgag
    17461 atgagctacc gcgggtccgg caggttggcc gggcgcaagg cgctgctgac cggcggcgac
    17521 tccgggatag gccgcgccgc ggcgatcgcc ttcgcgcgcg agggtgccga cgtcgccatc
    17581 aactatttgc cggtcgagga gtcggacgcg caggaggtga tcgcgttgat ccaggccgag
    17641 gggcgcaagg ccgtcgctgt ccccggggac atccgcgacg aggcgttttg caagcagctg
    17701 gtcgcggccg ccgtcgagca gctcggcggg ctcgacatcc tggtcaacaa cgcggcccgg
    17761 cagcaacagc gcaagtcgat cctcgagctg accaccgagg acttcgacgc caccttcaag
    17821 accaacgtgt acgcgatgtt ctggatcacc aaggccgcgc tgccgcacct gtcggccggc
    17881 gcgtcgatca tcaacacggc gtcggtccag gccgtcgatc cgtcggccca cctgctcgac
    17941 tatgcgcaga cgaaggcggc gatcgtcgcc ttctccaagt cgctggccaa gcagctcgca
    18001 ccgcagggga tccgcgtcaa cgcgatcgcg cccgggccgt tctggacgcc gctgcagccg
    18061 agcggcggcc agcctccgga caagctggtg aacttcggcg gcgacacccc gctcggccgc
    18121 ccgggccagc cggcggagat cgccccgcta tacgtgctgc tcgcgtcgga ggagtccagc
    18181 tattgcaccg ggcaggtgct cggcgcctcg ggcgggaccg gaaagtagtt ttttaaaaat
    18241 ttggcccggc gcgagccggc aagtccgtcg tcggaggtct cggccgctcg gtcgtcgacc
    18301 gcgcgcccgc ccggcgagag cggccgcaga gcgcggtgcg agtcgatcgt cgcgagcgcc
    18361 ggggtccgcg gacttgaagg tctcctacga gtgctcgagc tcgccgttcg attgcgggta
    18421 gccgggtgag atgcgatctc gaggccgacc cgtgcatcga gagggacacc tcggcgctgg
    18481 aggcgggaca cgcgggtcgc tacattcacc gagacaatga gccttcaacg tgcattcgta
    18541 cgaccgcgaa cggacgcttc atcgaggccc tcgatgcgac gggccatcat cagagcagcg
    18601 gacgtcgacc gcgagcggcc gcccgagaat gcacccggca aaacggccgc gacgacgcga
    18661 ttctcccgag gggtcggcgt cgcccgccgt tcatcggccg cacatcgggc gccgcggacg
    18721 atgcggactg cgccacacct ttcgcgacgc gaccgccttc tgcgcgctct tgcagctctc
    18781 ctcggcgagg aagcgctgca agaggtcgtc cggcgcgccg cgcgagcgag cccacgtcgt
    18841 tcacgcgcgg ggccgatgcc cggccgagcg agcccacgtc gttcacgtgc ggggcgcggg
    18901 ctcacgacga gcgcgcgcgg gcgtgggcga gcgtggtgac gcgcgcaagg acgcggacga
    18961 acgtacgtgc ggcccgacgg cgacctgcag gtcgcgccgc ggcccccgcg ccggcgacgc
    19021 catcgccgca cctcgaacgc gccccaccga gcccgggttg gggtacaaag ccgcccgcac
    19081 gatgccaacc agcgcaccca gagtcgggat cgacttcggc acctcgagct ccgcgctcgc
    19141 cctcgtcgac gccgagggtc gggtccgctt cgcccagctg ccgacgctcg gggtgctcgg
    19201 gccgagctgg cggacgctgc tgttcttcga ccccgacgat caggaggtcc agcagccgct
    19261 ccagtacacc gccgggggcg agggcatcga ggcctacctc gagtgcatgg gcgagggccg
    19321 cctgctgcag tcgttcaaga cccacctgac caccgagtcg atgggtcgca cgcaggtcgc
    19381 ccaccacgcg atcgggctcg acgacatgat cgcgctgttc ctgcagcggc tgcgcgagcg
    19441 cgccgagcag cacctgggag tcgcgctcga cgcggccacg atcggccggc cggtgcactt
    19501 cgccggcggg accacgcccg aggccgacgc gctcgcggcc gagcgcctgc tggccgccgc
    19561 gcgtcgggcc ggcttccgcg acgcccgcct cgagctcgag cccgtcggcg ccgcgcatca
    19621 ctacgagcgc acgctgacgc gccccgagct ggcgctggtc gccgacttcg gcgccggcac
    19681 caccgacttc tgcctgatgc gcatgggccc gaccggccac ggcagcacgc gcgcgcgcga
    19741 catcatcggc acgggcggcg tcggtgcggc cggcgacgac ctcgacgccg ccctcatcga
    19801 gcacctcgtg tgccctgccc tcggcaaggg cgacacctac gtcgagatgg gcgtcgagcg
    19861 ccagatcccc ggctcctact attataaatt ggcgcgctgg catcacctgc cgttcctcgc
    19921 cggcgcccgc gtgcgcgccg agctcgagcg cctgcgccgc ggcgcgcggc accccgagcg
    19981 gatcgccaag ctcatgcaca tcatcgccac caacggcgcg ttccacctgc acaaggcggt
    20041 cgagcgcacc aaggtcgagc tgtcgggccg caagcaggcc accttcgact tcagcgacgg
    20101 cgagatcgac atccacgccg ccgtgtcgcg ccgcgacttc gagcgctgga tcgccccgat
    20161 caccgcctcg atcgcggcct gcctcgacga caccctcgcc cgcgccggcg tgaccgcggg
    20221 cgaggtcgac tgcgtgttca tgaccggcgg caccgcgttc gtgccggtcg tccgcgcgct
    20281 gttcgaggcc cgcttcggcg ccgcgaagct gcgcagcggc gacgagctga tgtcgatcgc
    20341 gtccgggctg gccctgcgcg cggcggcgcc cgacgggggt tgaccgccgg cgtcgcccgc
    20401 tgcagggtct atcggacatg ccctcctgga catgtttaat tgaacatgtc tgatgtgaca
    20461 ttcccgaaga gacattctct gttcgacccc ccgtctcgcc gggtgtatcg ctgaattcgc
    20521 cgcgccgtta tttcagccgg atgcgcggcc agccggccgc ggacggcggt ccgattggac
    20581 atgtccgaag agacattctc ggccctccgc ccgggctccg gccgctgtcg ctgaagtcgg
    20641 cgagccgcgg gcatcgtcct gcccgggcag acgtccgatg ggacatgtcc gaagagacat
    20701 tctctcttcg accctccgcc tcgcccggcc tctcgcggaa cccgccgcgc ccgcgctatt
    20761 tcgggggatg cgcggccagc cagctgcgga cggtggactg ctcgggcagg taggcgggcc
    20821 cgaggccttg caggacgcgc agggcctgct cgacgagctc gcgatcgacg ggcccgagga
    20881 cgccggactc cgtcgtgcgg gcgcgggcga ggccgaagcg ggcgagcgcg agctcgaggg
    20941 tgtcgtggtc gctcagcacg ctgtagatgg cgacggcgcg ctggaagtga tcgcgggcgg
    21001 cggcgaggtc gttgcgcgcg agggcgaggt cgccgaggcg gaggcggatc agggccgcct
    21061 cggcgctctg gaccgtcgag ccgcgctcgc gcaggctctg ggcctgctgc agggccttcg
    21121 ccgcctcgtc gaggcggccg gcgatccggt ggacctcggc gatccggcgc agcgagtcgg
    21181 ccagcagcgg cgcgccggcg ggcaggcgcg tctggcggat ctccaggccg cgctggtact
    21241 gcaccagcgc cgcgtcggcg tccccggcgc gcagcagcat gtcgccgtgc agatcgtcga
    21301 tctcggcgct gcgcagctcg tcggcgccga agctctgctc ggcgatccgg tgcacgtgct
    21361 cgaagtggcg ccgggcagcg gcgaagtcgc cccggcaggt cgcgaccttc ccgaggccga
    21421 gcagggcgtt gatggccgcg gggtcgagcg aggtctcgct cgcgcccagc acctgcaagg
    21481 cgcggcggta gtgggcgtcg gcgtcgttgc agcggcgctg gtcgaccgcc aggtcgcccg
    21541 tggccgtgag cacccagtgc aggtcggcgg cgtcgggccc gagcagctcg ctctgcaggg
    21601 ccagcgcgcg ctggaagtaa ccggcggcct cgccgaagcg gtgcagcccg gtgaggccga
    21661 tgccgaggtt gatcgccagc agggccacgt gcgggtgttt ggggccgagg ctcgactcgg
    21721 cggcggtgaa ggcggtccgt aattggcgga cgccctcggg cgcgtcgccg ccgctgagca
    21781 gcaccaggcc gaggttgccg agcgcgtaca cgacctgcgg gtgctcctcg ccgaggaccg
    21841 cccggcgggc ctcgatcgag gcgacgaagt actcgcgcgc cgccgggaac tcgccgagca
    21901 ccgcgtgggc gatgccgagg ttgttgaggt gatcgccgcg cagctcgcga ccctcgcggg
    21961 tcgactcgac gcgcgcgacc aggccgtcga tcagcggggc gtcggtgagg acctcgcggc
    22021 tctgctgcaa gcgggccgcg cggacgaagt cgcggcgggt ggcgatggcc gcggcgacga
    22081 cgtcgtggcc gctggcgagc gcgacctgca gggcctcggt gagctcgcgg agggcctccg
    22141 ggtggcgacc ggcctcgctg agcaggctgc cgcgtcgcag gccgatctcg gcgaccaggg
    22201 gcgaataggc gagctcgccc agctcgaggc cctcgaccag ggcgaggccc cgggtgaact
    22261 gaccggcgag ctcgtgggcc tgggcctcgg ccaggacgcc gcgcaggccg gcgacgcggg
    22321 cggcgctggc ggggtcgtcg ggcggcggga cggcctccgt cagcgcccgc gtgtcgtcgc
    22381 agccggccag cgcgggcagg ttggcgg
//
