LOCUS       NZ_CP114040            21146 bp    DNA     circular CON 26-AUG-2024
DEFINITION  Nannocystis poenicansa strain FL3 chromosome, complete genome.
ACCESSION   NZ_CP114040
VERSION     NZ_CP114040.1
KEYWORDS    RefSeq.
SOURCE      Nannocystis poenicansa
  ORGANISM  Nannocystis poenicansa
            Bacteria; Myxococcota; Polyangia; Nannocystales; Nannocystaceae;
            Nannocystis.
REFERENCE   1  (bases 1 to 13228663)
  AUTHORS   Ahearne,A., Stevens,C. and Dowd,S.
  TITLE     Minimal conservation of predation-associated metabolite biosynthetic
            gene clusters underscores biosynthetic potential of Myxococcota
            including descriptions for ten novel species: Archangium lansinium
            sp. nov., Myxococcus landrumus sp. nov., Nannocystis bai
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 13228663)
  AUTHORS   Ahearne,A., Stevens,C. and Dowd,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-NOV-2022) Biomolecular Sciences, University of
            Mississippi, Faser Hall 407, Oxford, MS 38655, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2021
            Assembly Method                   :: IPA v. 10.1.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 250x
            Sequencing Technology             :: PacBio Sequel IIe
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_026965555.1-RS_2024_08_26
            Annotation Date                   :: 08/26/2024 12:45:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,229
            CDSs (total)                      :: 10,129
            Genes (coding)                    :: 10,068
            CDSs (with protein)               :: 10,068
            Genes (RNA)                       :: 100
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 9 of 61
            Pseudo Genes (incomplete)         :: 52 of 61
            Pseudo Genes (internal stop)      :: 2 of 61
            Pseudo Genes (multiple problems)  :: 2 of 61
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:28:22
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5975916
            Orig. end                         :: 5997062
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP114040.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21146
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="19"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21146
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21146
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11146](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11146
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            288..836
                     /locus_tag="O0S08_RS23050"
                     /old_locus_tag="O0S08_23050"
     CDS             288..836
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF016430.5"
                     /locus_tag="O0S08_RS23050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_23050"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_269041379.1"
                     /transl_table=11
                     /translation="MSEVQRQRAVADLFDRHADHVSRVLTRILGLDPETPDLIQEVFLR
                     AFRRIDRVRGEPEVLPRWLTGIAVYVAREHIRRKRGRWWLLWAGADGPLPEPPAATASP
                     DVVLAVHRVRSVIERLPVDERIPFTLRYLDDMELEEVADACDVSLATIKRRLARARARF
                     DKLAARDAILLNWVEKGRP"
     gene            833..1246
                     /locus_tag="O0S08_RS23055"
                     /old_locus_tag="O0S08_23055"
     CDS             833..1246
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS23055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_23055"
                     /product="hypothetical protein"
                     /protein_id="WP_269041380.1"
                     /transl_table=11
                     /translation="MTDRSADALLAALADAEERARVDARTPDGHAAQRARLLAAVSALA
                     DDDRLAMKSALAQPEAFILDRLNPLLGPAVARRALDLTRAGARDLPTAWPDVEAIGTSL
                     FTHLRPLVGEDIAGLVRQQLALGVLLWRELCAT"
     gene            1234..2034
                     /locus_tag="O0S08_RS23060"
                     /old_locus_tag="O0S08_23060"
     CDS             1234..2034
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS23060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_23060"
                     /product="hypothetical protein"
                     /protein_id="WP_269041381.1"
                     /transl_table=11
                     /translation="MRDLSRPRLLAAFLGLSAVGAVSHVVTDAGVMVPQLLLVAVVLTV
                     TAARAYKPGDPPRRAWIWLACATWLAVVGETVNAALGPGLSTWLMAVSNAMWCASLLDA
                     RRKIVAGALVPPLARAWRWALAAAVLVGLAVAFEVAWALRHGSPAYPHLGGARLYHLGF
                     VQLCDAVVLVAGVWLLGALHPLWGGAAARPFLLVTAAAGIFAASDLVPLFVDLPVPRPW
                     IRALIVGGWSLLGVAGLAQLELRRAMFASTADLRASLRGLGPRP"
     gene            complement(2139..3617)
                     /locus_tag="O0S08_RS23065"
                     /old_locus_tag="O0S08_23065"
     CDS             complement(2139..3617)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS23065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_23065"
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="WP_269041382.1"
                     /transl_table=11
                     /translation="MTRRTVAGLWTSALLLACGDAGAGASTGSTGSTGGSEAGETTAST
                     GATTSATTGPTTTGASTLPTTAGATTEESSGTGSSGQVTTEAATTEGPPIAGDPCVPWP
                     PAAGPVIEVTPAQAGELKAIIEGAAGGTTIAFAPGTYDVSGGAPIHITTPGLTLRGPSG
                     DRDAVVLDADYATGEILLIAASDTTVVDMTLQRAFWHPIHVTGGDAADITGVTIYDVKV
                     IDPGQQAIKINPSPANHYADEGLIACSWIELTDVGRPQIMDNCYTGGIDAHAAWGWTIR
                     DNDIRGFWCPEGLSEHAVHLWVTSRDTLVERNDIRDCARGVGFGLGENGNGNARAYADD
                     PCPGKSYLGHVGGEIRNNMIWAGDPSLFASQAGFDSGVALEQACDAKVLHNTVVSLQAP
                     FVSMEYRWANTSATIAGNLVTHDIVMRDGAQAQLDGNLEQAATDQFVDAAGADLHLAAG
                     SPAIDAAPAGLVAGDFDAEPREGSPDVGADEATR"
     misc_feature    complement(3733..3748)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.34"
                     /tool="antismash"
     misc_feature    3734..3748
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.64"
                     /tool="antismash"
     misc_feature    3761..3775
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.79"
                     /tool="antismash"
     gene            3774..4640
                     /locus_tag="O0S08_RS23070"
                     /old_locus_tag="O0S08_23070"
     CDS             3774..4640
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF044908.2"
                     /locus_tag="O0S08_RS23070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_23070"
                     /product="acyl-CoA thioesterase II"
                     /protein_id="WP_269041383.1"
                     /transl_table=11
                     /translation="MTHPADLARDTAVVRSPEGAARYVLDLPSHWNYFMPSGGALMTAA
                     LRAIAAEIDDPTQKPLSATAIFCVPVGEGPLVIDVVVLRRGQLATQVRAALSAAGGPFP
                     GLEVIATFGRERPGPELGLVRAPALPGPHELPSIDSRGESGGSPPFFRNYDCRRALGQP
                     WWRADRWAPGLDRAAYWYRYLTPQTLPDGQLDPLALPPLIDTMPPAMFQIGGPALAGTV
                     APSLDLTVHWLEDTRREWLLTHAHSRRARAGYATADIEIWDDEGRLVAWGNQRMLLRRR
                     PDLPPSR"
     gene            complement(4720..5685)
                     /locus_tag="O0S08_RS23075"
                     /old_locus_tag="O0S08_23075"
     CDS             complement(4720..5685)
                     /EC_number="1.14.13.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039286.4"
                     /locus_tag="O0S08_RS23075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_23075"
                     /product="aromatic ring-hydroxylating dioxygenase subunit
                     alpha"
                     /protein_id="WP_269041384.1"
                     /transl_table=11
                     /translation="MSSRFPFTANPIGWFMVAYSDELKPAGVMPLHYFGRELVLFRGQD
                     GAARVLDAHCPHLGAHLGHGGCVIENSITCPFHGWRFDGSGSCVGIPYAKKIPPAAMLR
                     RWAVCEKNGMIFVHHAPDESYAPTWDIPVLAEHESQAWTGYMRRRWRVRTNVHEIIENA
                     FDVAHFCFVHGAIRLPESKVTMNGPSFQVSSRTAFDTPAGVMEGDIDIDTFGFGMFTAR
                     YRGLIEGIIIAALTPIDDEFVDVRFTFTVKRLPDEAATAFVAQQFMEDACRQLEQDIAV
                     WEHKKFLPRPLLCEGDGPIGLFRKWARQFYPVATLRARAI"
     misc_feature    complement(5810..5824)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.9"
                     /tool="antismash"
     gene            complement(5852..6784)
                     /locus_tag="O0S08_RS23080"
                     /old_locus_tag="O0S08_23080"
     CDS             complement(5852..6784)
                     /NRPS_PKS="Domain: Abhydrolase_1 (32-287). E-value:
                     7.5e-31. Score: 99.5. Matches aSDomain:
                     nrpspksdomains_O0S08_RS23080_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.5"
                     /locus_tag="O0S08_RS23080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_23080"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_269041385.1"
                     /sec_met_domain="PF00561 (E-value: 7.5e-23, bitscore: 80.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.9e-18, bitscore:
                     67.1, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEASFPTTTLSVGGLQFTALEGSRSSARDRRRPLVLCLHGFPDHH
                     RTWRLQIPALEAAGFRVVAPLLRGYEPSSQPIDDDYHTIRMVEDVLGFIEYLGCLRVHL
                     VGHDWGAVIGYQVAARAPERLSSLTAMAVPHPRRLASLGALRLLPGQLRNSWYMFFFQL
                     RLLSDAALRRNDFALIDRLWRDWSPGFTPPAEEMRLLKRTFRQPGVASAALGYYRDMFD
                     PISRAAATSRALMREKVSVPTLALTGARDGCLDTRLFDLMRNEDFPHGLSVQRIAGAGH
                     FLHQERPEEVNEKLVDFLRRHEPGDIGCD"
     aSDomain        complement(5924..6688)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_O0S08_RS23080_Abhydrolase_1.1"
                     /evalue="7.50E-31"
                     /label="O0S08_RS23080_Abhydrolase_1.1"
                     /locus_tag="O0S08_RS23080"
                     /protein_end="287"
                     /protein_start="32"
                     /score="99.5"
                     /tool="antismash"
                     /translation="PLVLCLHGFPDHHRTWRLQIPALEAAGFRVVAPLLRGYEPSSQPI
                     DDDYHTIRMVEDVLGFIEYLGCLRVHLVGHDWGAVIGYQVAARAPERLSSLTAMAVPHP
                     RRLASLGALRLLPGQLRNSWYMFFFQLRLLSDAALRRNDFALIDRLWRDWSPGFTPPAE
                     EMRLLKRTFRQPGVASAALGYYRDMFDPISRAAATSRALMREKVSVPTLALTGARDGCL
                     DTRLFDLMRNEDFPHGLSVQRIAGAGHFLHQER"
     gene            6920..8356
                     /locus_tag="O0S08_RS23085"
                     /old_locus_tag="O0S08_23085"
     CDS             6920..8356
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1112: sigma-54
                     dependent trancsriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012241448.1"
                     /locus_tag="O0S08_RS23085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_23085"
                     /product="sigma-54 dependent transcriptional regulator"
                     /protein_id="WP_269041386.1"
                     /transl_table=11
                     /translation="MQQVLIVDDNPSVCTALEILFDVHGMSTQIAHTPQAALEIIARGD
                     VGAVVQDMNFQTDSTSGQEGAALFREIKRLDADLPVLLMTAWTSLETAVQLVKEGAADY
                     LGKPWDDAKVVTTVKNMLRMRELGLENHRLRAQSARARNELQRHYDLCGLVYASEAMHR
                     VVSLATSVARADAPVLITGPNGSGKEKLAEIVHANSPRKLQPFVKVNAGGLPDELLEAE
                     LFGAEIGAFTGATKRRIGRFEAADGGTLFLDEIGNLSPKGQMKLLRVLQTGEFERLGST
                     STKKVDVRIVSATNANLRQMIAQGVFREDLLFRLNVIEIRIPPLRERSEDVLPLAETFL
                     QAQVTPGREPLRLGDEAMRALLGHDWPGNVRELQNRIQRATLLCQSGEVTPADLGLDDK
                     APATDGTVTPRNHPSSDAKPAAVGNNEEIEAERRSIIAAIETHGGVIARAAAELGLSRQ
                     ALYRRMDRLGISLERQLKQS"
     misc_feature    6969..6984
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.89"
                     /tool="antismash"
     gene            8409..9626
                     /locus_tag="O0S08_RS23090"
                     /old_locus_tag="O0S08_23090"
     CDS             8409..9626
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063: argininosuccinate lyase/adenylosuccinate lyase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010852059.1"
                     /locus_tag="O0S08_RS23090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_23090"
                     /product="acetyl-CoA carboxylase biotin carboxylase subunit
                     family protein"
                     /protein_id="WP_269041387.1"
                     /sec_met_domain="ATP-grasp_3 (E-value: 2.3e-05, bitscore:
                     23.7, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 4.7e-06, bitscore:
                     25.5, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNILLLSPGYPGEMPSFTRGLADVGANVYGVGDQHPGALPPSVRE
                     RLAGYLQVRSLWDEAAVVEAVRRWPEARRIDKVECLWEPGMLLAARLREGLGVDGLGVA
                     QTLPFRDKEQMKQVLDAAGLRTPKHVRCNTTAECWDAAEQIGFPIIIKPIAGAGSADTY
                     RVESADELRAVLPRLGHVPEVSVEEFVDGSEFTFDTVCIEGKVAYFNIAWYRPRPLVAR
                     SNEWISPQVIALRNVDQPALAGGVKLGHDVIRALGFRSGFTHMEWYLKADGEVVFGEIG
                     ARPPGAHQVDQMNYACDFDVFREWGRAVAWGRFDVDIERKYNVSTIYKRAQGQGQIQRI
                     VGLDRIRKLYGEHIVWDNLLPVGAQRRNWRNTLVSDGFLMLRHPELQTLVAISDDIGEN
                     LQLYAG"
     gene            10001..11146
                     /locus_tag="O0S08_RS23095"
                     /old_locus_tag="O0S08_23095"
     CDS             10001..11146
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.4"
                     /locus_tag="O0S08_RS23095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_23095"
                     /product="terpene synthase family protein"
                     /protein_id="WP_269041388.1"
                     /sec_met_domain="T1TS (E-value: 1.4e-66, bitscore: 224.9,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRRFGTSPLSVRLAAVATTSATNRTGPRGRALVAVSGQQAGVAA
                     AAHAVDADPLASSSEPRQRLMQLPTLECPYHPSVHPAADEIHESTVAWAQAMGFARSQE
                     HIDALRDSRIGHLLARIFPATADMVALQVAVDWTTLFCCLDDRLEQMNGAAQVASYLRS
                     LLGVFRDGAHPQLIDPFAQAFGDLRERMLELRVPNWIPRFSACVERLFNAFVDEAKYRA
                     AGVVPAFASHSKIRQITVGLYTGFLLGELTEHIFLPPDVLEHEAVQALEVSASTIVGLA
                     NDIYTVEKEIAKGEVNNTVLVLMHEDGLAFDEAIGRTVQLHNIEMREFSRLVSDLPSFD
                     EDTDDQLRRYVQVLIHFISGHDDWARSTGRYHHPGDDSAVR"
     gene            11291..12535
                     /locus_tag="O0S08_RS23100"
                     /old_locus_tag="O0S08_23100"
     CDS             11291..12535
                     /NRPS_PKS="Domain: Aminotran_1_2 (36-388). E-value: 5e-47.
                     Score: 152.7. Matches aSDomain:
                     nrpspksdomains_O0S08_RS23100_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013256538.1"
                     /locus_tag="O0S08_RS23100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_23100"
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="WP_269041389.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 8.1e-45, bitscore:
                     152.7, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 2e-05, bitscore:
                     23.2, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPSLSRRGLDAPASPIRRLTPYADQARARGVTVHHLNIGQPDL
                     ATVQPMLAAYQAYDESVVAYSPSEGYLTYRTALAEHYNGLDAARGGGPITPGQILVTVG
                     GSEALLFAIAAACDVGDQILVAEPYYTNYRGFSHILGVDVVPVSTHARESFAVPPERVR
                     AAITPKTRAFIIPSPGNPTGMVLSAGDLAALGEVCVQAGIFFVVDEVYREFVYPDQPVP
                     AGAPVPRAPSVLAVPGLADHAVMIDSVSKRYSACGARVGCLVTRNAALYSACLRFAQAR
                     LSPPTVDQYAALAALRTPAADMRAMVDEYRARRDLIVAGLNAIPGVSCPTPTGAFYLIT
                     DLPVADAEDFCIFMLRDFDLGGETVMMAPAEGFYATPGLGKNQVRIAYVLGRDKLARCL
                     EILRAGLDAYNRAAR"
     aSDomain        11399..12454
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_O0S08_RS23100_Aminotran_1_2.1"
                     /evalue="5.00E-47"
                     /label="O0S08_RS23100_Aminotran_1_2.1"
                     /locus_tag="O0S08_RS23100"
                     /protein_end="388"
                     /protein_start="36"
                     /score="152.7"
                     /tool="antismash"
                     /translation="HLNIGQPDLATVQPMLAAYQAYDESVVAYSPSEGYLTYRTALAEH
                     YNGLDAARGGGPITPGQILVTVGGSEALLFAIAAACDVGDQILVAEPYYTNYRGFSHIL
                     GVDVVPVSTHARESFAVPPERVRAAITPKTRAFIIPSPGNPTGMVLSAGDLAALGEVCV
                     QAGIFFVVDEVYREFVYPDQPVPAGAPVPRAPSVLAVPGLADHAVMIDSVSKRYSACGA
                     RVGCLVTRNAALYSACLRFAQARLSPPTVDQYAALAALRTPAADMRAMVDEYRARRDLI
                     VAGLNAIPGVSCPTPTGAFYLITDLPVADAEDFCIFMLRDFDLGGETVMMAPAEGFYAT
                     PGLGKNQVRIAY"
     gene            12867..13664
                     /locus_tag="O0S08_RS23105"
                     /old_locus_tag="O0S08_23105"
     CDS             12867..13664
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025124.5"
                     /locus_tag="O0S08_RS23105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_23105"
                     /product="ATP-binding protein"
                     /protein_id="WP_269041390.1"
                     /transl_table=11
                     /translation="MSLVAPTPLGFERSPVAGASVDDLDLAALEAYVRRRVPGLGTEPG
                     VFERAAQRLGLIGTTGGQPTPTVVGLMAFGTAPQVARPEWGVSIVRIRGAALADPVAAR
                     LDAEGNLAELVRLGLEFVRANTRAAPNLLIPSDLAPEYPEEAVREALVNALVHRDYRLS
                     GRVSLRIFNDRLEIWSPGGLALPISLDELAQHGGASFPRNPLLAATARHLGLLEQIGRG
                     IPAIRRSIAGATALPVQFHTSQTEVRVVLPSYINASMGNVSGN"
     gene            complement(13952..14359)
                     /locus_tag="O0S08_RS23110"
                     /old_locus_tag="O0S08_23110"
     CDS             complement(13952..14359)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS23110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_23110"
                     /product="hypothetical protein"
                     /protein_id="WP_269041391.1"
                     /transl_table=11
                     /translation="MREACCEALADCQADASCLACVSGEDGEACESNPDTHARVDAYLE
                     CKGAACQEACIGGPVGSCEDALAELGQDACTTCLGTNCCDEIAGCHANTVCWTGCFTVH
                     DDAVCHSDPDGHALYHALSACASQSCQAECF"
     gene            14358..14735
                     /locus_tag="O0S08_RS23115"
                     /old_locus_tag="O0S08_23115"
     CDS             14358..14735
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS23115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_23115"
                     /product="hypothetical protein"
                     /protein_id="WP_269041392.1"
                     /transl_table=11
                     /translation="MQPVHSSVASPAHAASVVADEAVVAVELAAVVASVVGSCVVVVVV
                     SALVLADDVVASEVAPVSTPLVVAPLVVASVPDTGASVDDVDSAPQASAAAKTRKDSGD
                     RAGAGMVMSATMVRSNDIHFQ"
     misc_feature    14788..14803
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 22.18"
                     /tool="antismash"
     misc_feature    14788..14806
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.92"
                     /tool="antismash"
     misc_feature    complement(14789..14805)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 18.76"
                     /tool="antismash"
     misc_feature    complement(14790..14803)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 19.04"
                     /tool="antismash"
     misc_feature    14790..14804
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.86"
                     /tool="antismash"
     misc_feature    14791..14804
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.05"
                     /tool="antismash"
     misc_feature    complement(14791..14806)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 21.07"
                     /tool="antismash"
     misc_feature    14793..14807
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 18.93"
                     /tool="antismash"
     gene            15062..15670
                     /locus_tag="O0S08_RS23120"
                     /old_locus_tag="O0S08_23120"
     CDS             15062..15670
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006975760.1"
                     /locus_tag="O0S08_RS23120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_23120"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_267707315.1"
                     /transl_table=11
                     /translation="MQPDEELYVAWRGGDSKAGVQLFERHYPAIARFFRNKVDDDAGDL
                     VQKTFLACLESKERIRGDSSFRTFLFAVAHNVLYKHLRGKLREGARLDFGLTSVHDLRP
                     TPATLLARRREERLLLLGLRRIPLDHQVLLELYFWEKLGAREIADILGVPEGTIRTRLR
                     RAKQLLEAAMTALEDGAAELRDSLGDLDAWAAAVRGQIG"
     gene            15693..18074
                     /locus_tag="O0S08_RS23125"
                     /old_locus_tag="O0S08_23125"
     CDS             15693..18074
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS23125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_23125"
                     /product="hypothetical protein"
                     /protein_id="WP_269041393.1"
                     /transl_table=11
                     /translation="MSIHAVRRHFTTPALRRRWFVLLFTLGLTTQPLFGALGYEGALVL
                     TPVISLFALAVGVDAVRDTRQAHASDPHAMSLQTSGERLRLLFLRGLGDLCSLLTLSLG
                     AFILANFWQINCDLPGGLLWFLVLPTASGLLGLVAGLWGGVLAHRRGVQLALASVPLVF
                     SLVLGLWRIYVDPVVYAIDPFWGYFAGPLYDEAIPITARLWWFRAYNFLVAGAALALLS
                     LTLGPGLKVQLRGVSLRRSPFTVAALLACLMPGALLGVFAAENGFHATEASLANALPRT
                     RVTDHFVIHYAANSAAARDIDLLAAEHEFAWRRLAAQIGREPRVPVHSFVFPTPELKRA
                     WIGAGNTEVAPPWRGHIYLNEQAFPHRVLHHELAHVFSYTVGEPLFGTSSAVSWRGLRV
                     NLALIEGFATAFAPRSESGLDLHDQAAILDRLELRPVLGDIMGFGFWGKSSRRAYTAAG
                     SFCRWLIDTRGVEPFLRLYGTAGDFDLSYGTSLDALEVEWLAFLRARPLRARDVEALRQ
                     RFKQRPIFQRPCAHRAADLLAEANLAHHRGLEVERIDTLRDLCSIEPEQPEHRLLLAQA
                     EAQAGMQDAAAATLAELSRQNDLSDTIAALVDERLGDLALARFDLPVALTYYDRALTRG
                     LGDNQIRQLQIKRMGAADPALAPRVLAYFDPFEPNPEHPSEAVLRLYAAEQIAALPRYA
                     PLGGYLLGRQLLNVQQGAAAIEPLQRALHPEEDEHALSTAELRRGARLMLLEAQARARN
                     YDAAARVLAELQEDPDADSGLRLDAALWTERLEFLRTHLP"
     misc_feature    complement(18168..18183)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.75"
                     /tool="antismash"
     misc_feature    complement(18338..18353)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.75"
                     /tool="antismash"
     misc_feature    18431..18446
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     gene            18501..18941
                     /locus_tag="O0S08_RS23130"
                     /old_locus_tag="O0S08_23130"
     CDS             18501..18941
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS23130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_23130"
                     /product="hypothetical protein"
                     /protein_id="WP_269041394.1"
                     /transl_table=11
                     /translation="MSHHDPAQARGPVRQARTAIGHRPSCASYSSKTTIRFISFGKNMG
                     HNEDEMSVSRRTRTATIARLCVWTGLFVAAATHLTVEPSRVSANPEPAARVEPLKRPLA
                     AAEEDMSLRAAFEAAGAIALSTRPYPTCPFDQACDSPDEAAR"
     misc_feature    18834..18836
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            18960..19850
                     /locus_tag="O0S08_RS23135"
                     /old_locus_tag="O0S08_23135"
     CDS             18960..19850
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS23135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_23135"
                     /product="hypothetical protein"
                     /protein_id="WP_269041395.1"
                     /transl_table=11
                     /translation="MSRRATALLLACACVPAADAPGTSATDTIITTSIATTGTTATTSA
                     APTTTTATSTSEALTSGGVTFIQPPDGGGSKECDLFEQDCPEGMKCSPHSADGDNAWET
                     LKCVDVVPAPAGFHEPCQLLGVPASGEDTCDEGLMCWFTQSDTGVGICLPHCTGSPDAP
                     VCAPGSRCSSTFPGEDILSLCLPSCDPLAQDCPNGGPCTPWDEEFWGCYSDDSGDEGQA
                     FDPCVHVRACDPGLTCAEPELADECDPRANGCCLPYCDLDLPNTCPGQGQACVAWYVPG
                     QAPPGLEDVGLCALP"
     misc_feature    complement(19883..19892)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.27"
                     /tool="antismash"
     gene            19949..20914
                     /locus_tag="O0S08_RS23140"
                     /old_locus_tag="O0S08_23140"
     CDS             19949..20914
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS23140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_23140"
                     /product="hypothetical protein"
                     /protein_id="WP_269041396.1"
                     /transl_table=11
                     /translation="MSRRPRVLLPLVLAACVARPTGDTDDAPTGGPATTTTGDPEPGTS
                     GGTTTASTTAPGTTLPPPTTTDPTTAFPTTGEPAPTTEALTTTPFLPAPDFSNPNECDP
                     WIEDCPEGQKCMAWASDGGSSWNSTKCVDIVPDPDGLGEPCSVIGSPVSGEDTCGKHLQ
                     CFFADPDTLQGTCLAMCVGSPDNPDCEQPDATCALSGDGVLILCVPDCDPLAPDCGPGE
                     VCVSNNGSNFTCVFDASGDEGQLFDPCEFINACDPGLACVNSELAGECDPDVFGCCLPH
                     CDLTAPPSCPGAGQECLPWFEQGQAPPGHEDLGVCGLPPP"
     misc_feature    complement(21045..21065)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.4"
                     /tool="antismash"
ORIGIN
        1 ctcgcgctcg gcgatcgcca gcgccgaacc gcgcgcctcg agccgcttgt tcatctctcg
       61 caccatctcg accgtaatcg tcggcatctc cactcctccc aatgctccgc agacccgcgg
      121 ccacgacggc gcgccgggtg caggtgtcgt taagtggcga gctttcgaga tcgcggctca
      181 gcaatttttc gtcgcgcact cgcgctcgcc ttcaggtcgc tagagcgcgg gcccgcgctt
      241 gacttccccg tccgggtcgc gcatcaaccc cgcgaggcgg gtgaaggttg agcgaggtcc
      301 agcgccagcg agccgtcgcc gacctgttcg accgccacgc cgatcacgtg tctcgcgtgc
      361 tcacgcggat cctcgggctc gacccggaga cgcccgatct gatccaggag gtgttcctcc
      421 gcgccttccg ccgcatcgat cgcgtgcgcg gcgagcccga ggtcctgccg cggtggctga
      481 ccgggatcgc ggtgtacgtc gcgcgcgagc acatccgccg caagcgcggc cgctggtggc
      541 tgctctgggc cggcgccgac gggccgctgc ccgagccgcc ggccgcgacc gcgagccccg
      601 acgtcgtcct ggccgtgcac cgcgtccgca gcgtcatcga gcgcctgccg gtcgacgagc
      661 ggatcccgtt caccctgcgc tacctcgacg acatggagct cgaagaggtc gccgacgcct
      721 gcgacgtatc gctggcgacc atcaagcgcc gactcgcccg cgcccgcgct cgcttcgaca
      781 agctcgcggc gcgcgacgcc atcctcctca actgggtgga gaagggacga ccatgaccga
      841 tcgatctgcg gatgccctgc tcgccgcgct cgccgacgcc gaagagcgcg cccgcgtcga
      901 cgcgcgcacc ccggacggcc acgcggccca gcgcgcgcgc ctgctcgccg ccgtctctgc
      961 gctcgccgac gacgaccgcc tggccatgaa gtctgcgctc gcgcagcccg aggccttcat
     1021 cctcgaccgc ttgaacccgc tgctcgggcc cgcagtggct cgccgcgcgc tcgacctcac
     1081 ccgcgccggc gcgcgcgact tgccgaccgc gtggcccgac gtcgaggcca tcggcacgtc
     1141 cctgttcacg cacctgcggc cgctcgtcgg cgaggacatc gccggcctcg tgcgtcagca
     1201 gctcgcgctc ggcgtcctgc tgtggaggga gctgtgcgcg acctgagccg cccgcgcctg
     1261 ctcgctgcct tcctcggcct gagcgccgtc ggggccgtca gccacgtcgt caccgacgcc
     1321 ggcgtgatgg tgccgcagct gctgctcgtc gcggtcgtcc tcaccgtcac cgccgcgcgc
     1381 gcctacaagc ccggcgaccc accgcgccgc gcgtggatct ggctggcctg cgccacctgg
     1441 ctcgcggtcg tcggcgagac cgtcaacgcc gctctcggcc cgggtctcag cacctggttg
     1501 atggccgtgt ccaacgcgat gtggtgcgcc tccctgctcg acgcccggcg caagatcgtc
     1561 gccggcgcgc tggtccctcc gctcgcgcga gcgtggcgct gggccctcgc cgccgccgtc
     1621 ctcgtcggcc tcgcagtcgc cttcgaggtc gcgtgggcgc tgcgccacgg cagccccgcg
     1681 tacccgcacc tcggcggcgc gcgcctctat cacctcggct tcgtccagct gtgcgacgca
     1741 gtcgtcctgg tggccggcgt gtggctgctc ggcgccctgc atcctttgtg gggcggcgcc
     1801 gcggcccgcc cgttcctcct cgtcacggcc gccgccggca tcttcgccgc cagcgacctc
     1861 gtcccgctgt tcgtggacct gcccgtgccg cggccgtgga tccgcgccct catcgtcggt
     1921 ggttggtcgc tgctcggcgt cgccggcctg gcccagctcg agctccgcag ggccatgttc
     1981 gccagcacgg ccgacctccg cgccagcctg cgaggcctcg gcccgcggcc atgacttgtc
     2041 catgggacat gtcgatgcgg tcatgccttt aagatcatgt tctatgggac attctccatc
     2101 gagcatgact ccatggacat gtcgcatcgc tccgcatctc accgcgtcgc ctcgtccgcg
     2161 ccgacgtcgg ggctgccctc gcgcggctcg gcgtcgaagt ccccggcgac cagccccgcc
     2221 ggcgccgcgt cgatcgccgg cgagcccgcg gccaggtgca ggtcggcccc ggccgcgtcg
     2281 acgaattgat ccgtcgctgc ctgctcgagg ttgccgtcga gctgcgcctg cgccccgtcg
     2341 cgcatcacga tgtcgtgcgt gaccaggttg ccggcgatcg tcgcgctggt gttggcccag
     2401 cggtactcca tcgacacgaa cggcgcctgc aggctgacga ccgtgttgtg cagcaccttc
     2461 gcgtcgcacg cctgctcgag cgccacgccg gagtcgaagc ccgcctgcga cgcgaacagc
     2521 gaggggtcgc cggcccagat catgttgttg cggatctccc cgccgacgtg gccgaggtag
     2581 ctcttgcccg ggcacgggtc gtcggcgtag gcgcgcgcgt tgccgttgcc gttctcgccg
     2641 aggccgaagc cgaccccgcg ggcgcagtcg cggatgtcgt tgcgctcgac cagcgtgtcg
     2701 cgggacgtca cccacaggtg aaccgcgtgc tccgacagcc cctccgggca ccagaacccg
     2761 cggatgtcgt tgtcgcggat cgtccagccc caggccgcgt gggcgtcgat gccgccggtg
     2821 tagcagttgt ccatgatctg cggccggccg acgtcggtca gctcgatcca cgagcacgcg
     2881 atcagcccct cgtcggcgta gtgatttgcg ggcgacgggt tgatcttgat cgcctgttgc
     2941 cccgggtcga tcaccttcac gtcgtagatc gtcaccccgg tgatgtcggc cgcgtcgccg
     3001 ccggtcacgt ggatcgggtg ccagaacgcc cgctgcagcg tcatgtcgac caccgtcgtg
     3061 tccgacgccg cgatcagcag gatctccccc gtcgcgtagt cggcgtcgag caccaccgcg
     3121 tcgcggtcgc cgctcggccc gcgcagcgtc agcccgggcg tcgtgatgtg gatcggcgcc
     3181 ccgcccgaca cgtcgtaggt ccccggcgcg aacgcgatcg tcgtccctcc ggccgcgccc
     3241 tcgatgatgg ccttcagctc gcccgcctgc gccggcgtca cctcgatcac cggcccggcc
     3301 gcgggcggcc acgggacgca cggatcgccc gcgatcggcg gcccctcggt ggtcgccgcc
     3361 tcggtcgtta cctgtccgga agaacctgtc ccggaagact cctccgtcgt cgccccggcg
     3421 gtcgtcggca gcgtcgaagc gcccgtcgtc gtcggcccgg tcgtcgccga cgtcgtcgcg
     3481 ccggtgctcg cagtcgtctc gcccgcctcg ctgccgcccg tgctgcccgt gctgcccgtg
     3541 ctcgccccgg cgcccgcgtc gccgcaggcg aggagcagcg cgctcgtcca caggcccgcg
     3601 accgtgcgtc tcgtcatcgc cgtactctac gccggcgtcc tcccccgcga ccgcgcgggc
     3661 ccgtgaggac cgccgggcca ccgcggcctc gaggacctcc gcggcaacgc tcacccgccc
     3721 gggcaggcca cggaacattg ttctcgatgg cgttccaggt atcatcgccg gcgatgacgc
     3781 accccgccga tctcgcgcgc gacaccgccg tcgtgcgcag ccccgagggc gccgcgcgct
     3841 acgtcctcga cctcccgtcg cactggaact acttcatgcc ctcgggcggc gcgctgatga
     3901 ccgcggcgtt gcgggcgatc gcggccgaga tcgacgaccc gacgcagaag ccgctgtcgg
     3961 ccaccgccat cttctgcgtc cccgtcggcg agggtccgct cgtcatcgac gtcgtcgtcc
     4021 tgcggcgcgg ccagctggcg acccaggtcc gcgccgcgct gtcggccgcc ggcggtccgt
     4081 tccccggcct cgaggtcatc gccactttcg ggcgcgagcg tcccggcccc gagctcggcc
     4141 tcgtccgtgc ccccgcgctg cccggcccgc acgagctgcc gtcgatcgac tcgcgcggcg
     4201 agagcggcgg ctccccgccg ttcttccgca actacgactg tcggcgcgcg ctcggccagc
     4261 cgtggtggcg cgccgatcgc tgggcgccgg gcctcgatcg cgccgcctac tggtaccgct
     4321 acctgacccc gcagaccttg cccgacggcc agctcgaccc gctggccctg ccgccgctca
     4381 tcgataccat gccgccggcg atgttccaga tcggcggccc cgcgctcgcc ggcaccgtcg
     4441 cccccagcct cgacctcacc gtccactggc tcgaggacac ccgccgtgag tggctgctga
     4501 cgcacgcgca cagccgccgc gcccgcgccg gctacgccac cgccgacatc gagatctggg
     4561 acgacgaggg ccgcctggtc gcgtggggca accagcgcat gctactgcgc cgacgacccg
     4621 atctaccgcc gtcgcgctga gcgtgctccc acggacatgc cccatcgggc atgcctccgc
     4681 ggacatgtct gcctggacat gccccgagaa acctatccct cagatcgccc gggcccgcag
     4741 ggtcgccacc gggtagaact ggcgggccca cttgcggaac aggccgatgg gcccgtcgcc
     4801 ctcgcacagc agcgggcggg gcaggaactt cttgtgctcc cacaccgcga tgtcctgctc
     4861 gagctggcgg caggcgtcct ccatgaactg ctgggccacg aacgcggtgg ccgcctcgtc
     4921 gggcaggcgc ttgaccgtga aggtgaagcg gacgtcgacg aactcgtcgt cgatgggcgt
     4981 cagcgcggcg atgatgatcc cctcgatcag cccgcggtag cgggcggtga acatgccgaa
     5041 gccgaacgtg tcgatgtcga tgtcgccctc catcaccccg gccggggtgt cgaaggcggt
     5101 ccgcgagctg acctggaacg acggcccgtt catcgtcacc ttcgactcgg gcaggcggat
     5161 cgcgccgtgg acgaagcaga agtgggccac gtcgaacgcg ttctcgatga tctcgtggac
     5221 gttggtgcgg acgcgccagc gccggcgcat gtagccggtc cacgcctggg actcgtgctc
     5281 ggccagcacc gggatgtccc acgtcggcgc gtacgactcg tcgggcgcgt ggtggacgaa
     5341 gatcatcccg ttcttctcgc acaccgccca gcggcgcagc atcgccgcgg gcgggatctt
     5401 cttcgcgtac gggatcccca cgcacgagcc cgacccgtcg aagcgccagc cgtggaacgg
     5461 gcaagtgatg ctgttctcga tcacgcagcc gccgtgcccg aggtgggcgc cgaggtgggg
     5521 gcaatgcgcg tcgagcacgc gggccgcccc gtcttgcccg cggaacagca ccagctcgcg
     5581 cccgaagtag tgcagcggca tcacgccggc cggcttcagt tcgtcggagt aggcgaccat
     5641 gaaccaaccg atcgggttgg cagtgaacgg aaagcgactg ctcatctcgg agcccccttg
     5701 tgcgggcaaa cgtgggcagg tcccacaccc caaggatgtg acgggcgccg ctctcgccgc
     5761 gcctccgcgg cgcatcaccg tgcgaaccac gttcgtccgc cgctcgggcc ggaccggcaa
     5821 ttccgcccgc ggcgatgcgc acgccgcgac ctcaatcgca gccgatgtcg ccgggctcgt
     5881 ggcggcggag gaagtcgacc agcttctcgt tgacctcctc tggccgctcc tggtggagaa
     5941 agtgccccgc gcccgcgatc cgctggaccg acagaccgtg ggggaagtcc tcgttgcgca
     6001 tgagatcgaa cagccgggtg tcgaggcagc cgtcgcgcgc cccggtcagc gccagcgtcg
     6061 gcaccgagac cttctcccgc atcagcgccc gcgaggtcgc ggcggcccgg ctgatcgggt
     6121 cgaacatgtc gcgatagtac ccgagcgcgg ccgaggccac ccccggctgg cggaacgtgc
     6181 gcttcaacag ccgcatctcc tcggccggcg gggtgaaccc cggcgaccag tcgcgccaca
     6241 gcctgtcgat cagcgcgaag tcgttgcgcc gcagcgccgc gtcggacaag agccgcagct
     6301 gaaagaagaa catgtaccag gagttgcgga gctgccccgg gagcagccgc agcgccccca
     6361 gcgacgccag ccgccgcggg tgcggcactg ccatcgccgt cagcgacgac agccgctccg
     6421 gcgcccgggc cgcgacctgg tagccgatca ccgcccccca gtcgtgcccg accaggtgga
     6481 cgcgcaggca gccgaggtac tcgatgaagc ccagcacgtc ctcgaccatc cggatcgtgt
     6541 ggtagtcgtc gtcgatcggc tgggacgacg gttcgtagcc gcggagcagc ggcgccacca
     6601 cgcggaagcc cgccgcctcg agcgccggga tctgcagccg ccaggtccgg tgatggtcgg
     6661 ggaagccgtg cagacacagc accagcggcc gccggcggtc gcgcgccgac gagcgggatc
     6721 cctccagcgc ggtgaactgt agtccgccca cggacaaagt ggtcgtcggg aagctcgctt
     6781 ccatgccgcc caagacgtac caccgcaaac gccgaggcgc gaggaccgcc gcgcgcgccc
     6841 gcccgaaacg ggggtgtggg cgcatgctcg ccgcgaaaca acacccgcag gcgcgcgaag
     6901 gcagggtaaa accctggcca tgcagcaggt gctcatcgtc gacgacaacc cctcggtctg
     6961 caccgccctc gagatcctgt tcgacgtcca cgggatgagc actcagatcg cccacacccc
     7021 gcaggccgcg ctcgagatca tcgcccgggg cgacgtcggg gctgtcgttc aggacatgaa
     7081 ctttcagaca gactcgacct cgggccagga gggcgccgcg ctgttccgcg agatcaagcg
     7141 cctcgacgcc gacctgccgg tgctcctcat gaccgcctgg acctcgctcg agaccgcggt
     7201 ccagctggtc aaggaaggcg ccgccgacta cctcggcaag ccgtgggacg acgccaaggt
     7261 cgtcaccacc gtcaagaaca tgctgcgcat gcgcgagctc gggctcgaga accaccgcct
     7321 gcgggcccag tcggcgcgcg cgcgtaacga gctgcagcgc cactacgacc tgtgcggcct
     7381 ggtctacgcc agcgaggcga tgcaccgcgt cgtctcgctc gccacctcgg tcgcccgcgc
     7441 cgacgcgccg gtcctcatca ccgggccgaa cggctccggc aaggagaagc tggccgagat
     7501 cgtccacgcc aacagcccgc gcaagctgca gccgttcgtc aaggtcaacg ccggcggcct
     7561 gcccgacgag ctgctcgagg ccgagctgtt cggcgccgag atcggcgcct tcacgggcgc
     7621 gaccaagcga cggatcggcc gcttcgaggc cgccgacggc ggcaccctgt tcctcgacga
     7681 gatcggcaac ctgtcgccga agggtcagat gaagctgctg cgcgtgctgc agaccggcga
     7741 gttcgagcgg ctcggcagca ccagcaccaa gaaggtcgac gtccgcatcg tctcggccac
     7801 caacgccaac ctgcggcaga tgatcgccca gggggtgttc cgcgaggacc tgctgttccg
     7861 cctcaacgtc atcgagatcc ggatcccccc gctgcgcgag cgcagcgagg acgtcctgcc
     7921 gctggcggag accttcctgc aggctcaggt cacccccggg cgcgagccgc tgcggctcgg
     7981 cgacgaggcc atgcgcgccc tcctcggcca cgactggccc ggcaacgtcc gcgagctgca
     8041 gaaccggatc cagcgggcca ccctgctgtg tcagagcggc gaggtcaccc ccgccgacct
     8101 cgggctcgac gacaaggcgc cggcgaccga cggcaccgtc accccgcgca atcacccgtc
     8161 gtcggacgcc aagccggcgg ccgtcggcaa caacgaggag atcgaggccg agcggcgctc
     8221 gatcatcgcc gccatcgaga cccacggcgg cgtcatcgcc cgcgccgcgg ccgagctcgg
     8281 gctgtcgcgt caggccctct accgccgcat ggaccggctc gggatcagcc tcgagcggca
     8341 gctcaagcag agctgaatcg ttgcgtccgc ccgggcgccc tgataccgat cctcggcgga
     8401 gctttcgcat gaacatcctg ctcttgtccc ccggctatcc cggcgagatg cccagcttca
     8461 cccgcggcct cgccgacgtg ggcgcgaacg tctacggcgt cggcgaccaa cacccgggtg
     8521 ccttgccgcc gtcggtgcgc gagcgcctcg ccggttactt gcaggtccgt tcgctgtggg
     8581 acgaggccgc cgtggtcgag gccgtgcgcc gctggccgga ggcgcgccgg atcgacaagg
     8641 tcgagtgtct gtgggagccg ggcatgctgc tggccgcgcg cctgcgcgaa ggcctcggcg
     8701 tcgacggcct cggcgtcgcc cagaccttgc cgttccgcga caaggagcag atgaagcagg
     8761 tcctcgacgc cgccggcctg cgcacgccga agcacgtccg ctgcaacacc accgccgagt
     8821 gttgggacgc cgccgagcag atcggcttcc cgatcatcat caagccgatc gccggcgccg
     8881 gctcggccga cacctaccgg gtcgagtccg ccgacgagct gcgggccgtc ctgccgcgcc
     8941 tcgggcacgt ccccgaggtc agcgtcgagg agttcgtcga cggctcggag ttcaccttcg
     9001 acaccgtctg catcgagggc aaggtcgcct acttcaacat cgcctggtat cgcccgcggc
     9061 cgctcgtcgc gcgcagcaac gagtggatca gcccccaggt gatcgccctc cgcaacgtcg
     9121 accagcctgc gctcgcgggc ggcgtcaagc tggggcacga cgtcatccgc gcgctcggct
     9181 tccgctccgg cttcacccac atggagtggt acctgaaggc cgacggcgag gtggtcttcg
     9241 gcgagatcgg cgcccgcccg cccggcgccc accaggtcga ccagatgaac tacgcctgcg
     9301 acttcgacgt gttccgcgaa tggggtcggg ccgtcgcctg ggggcgcttc gacgtcgaca
     9361 tcgagcgcaa gtacaacgtc agcacgatct acaagcgcgc ccagggtcag ggccagatcc
     9421 agcggatcgt cggcctcgac cggatccgca agctctacgg ggagcacatc gtctgggaca
     9481 acttgctgcc ggtcggtgcc cagcgccgta actggcgcaa caccctcgtc tccgacggct
     9541 tcttgatgtt gcgccacccc gagctgcaga cgctcgtggc gatcagcgac gacatcggcg
     9601 agaacctgca gctttacgcc ggctgagcgt ccccggacca gctgttctcc aggacagccg
     9661 cggccgcaga gggtcgggcg aggtcgcgcg ccttctgcgc gattcgatgt accggcaccg
     9721 ttcgcggtcg cagctccgcc tgcatcgccc ccgtggtcca ggccccgcag tcgcgtgccg
     9781 tcggcgcggt caaggttcgt catgtcgagg tgcccacgcc aaggcacacc accccaccga
     9841 aatcgccgcc aaagtgcggc atgcaggtgg atccggtata gcttgaagtg gcgtggtggt
     9901 cggagtgcca atgaagccgc ggaggcaggt gcaagcgtgt gccggcttgc tgcggcgagt
     9961 gatccgacgc cggatcccag acgctgatcg aaagagctcc atgacccgcc ggttcggaac
    10021 cagcccgctc agcgtccgcc tcgccgcggt cgcgacgacg tcggcgacga accgcacggg
    10081 gccgcgaggg cgcgcgctgg tggccgtctc cgggcagcag gccggggtgg cggcggcggc
    10141 gcacgctgtc gacgccgacc ctctcgcgtc atcgtcggag ccgcggcagc gtctgatgca
    10201 gctccccacg ctcgagtgcc cgtaccaccc gtcagtccat cccgccgccg acgagatcca
    10261 cgagagcacc gtcgcgtggg cccaggcgat gggtttcgcg cgcagccagg agcacatcga
    10321 cgccctgcgc gacagtcgga tcggtcactt gctcgcgcgg atcttcccgg ccaccgccga
    10381 catggtcgcg ctgcaggtcg ccgtcgactg gaccaccctg ttctgctgcc tcgacgatcg
    10441 cctcgagcag atgaacggcg ccgcgcaggt cgcctcctac ctccgcagcc tgctcggcgt
    10501 gttccgcgac ggcgcccacc cgcagctcat cgacccgttc gcccaggcgt tcggcgacct
    10561 gcgcgagcgc atgctcgagc tgcgggtgcc caactggatc ccgcggtttt cggcctgcgt
    10621 cgagcgcctc ttcaacgcct tcgtggacga ggccaagtac cgcgcggccg gcgtcgtccc
    10681 ggcgttcgcc agccacagca agatccgcca gatcaccgtc ggcctctaca ccggcttcct
    10741 cctcggcgag ctcaccgagc acatcttcct cccgccggac gtcctcgagc acgaggcagt
    10801 gcaggcgctc gaggtcagcg ccagcaccat cgtcggcctc gccaacgaca tctacaccgt
    10861 cgagaaggag atcgcgaagg gcgaggtcaa caacaccgtg ctcgtgctca tgcacgagga
    10921 cggcctcgct ttcgacgagg cgatcggccg cactgtccag ctgcacaaca tcgagatgcg
    10981 cgagttctcg cggctcgtct ccgacctgcc gagcttcgac gaggacaccg acgaccagct
    11041 gcgccgctac gtccaggtcc tgatccactt catctccggg cacgacgact gggcgcgcag
    11101 caccggtcgc taccaccacc ccggggacga cagcgccgtg cgttgacgcg atcgcaccgg
    11161 ccgcgcccgc gaggcgcgcc ggcgggaacg cgcccgggcg ggcccctgcg ccgcgcttgc
    11221 gctcgttcac gcggcgccgg ccgcagcggc cttctcaagc gcgtcaaacc gtctcacact
    11281 ccgcgtgccc atgaccgcac ccagcctgtc ccgccgcggg ctcgacgccc cggcgtcccc
    11341 gatccgccgc ctcactccgt acgccgatca ggcgcgggcg cgcggggtca ccgtgcacca
    11401 cctcaacatc ggtcagcccg acctcgccac cgtgcagccg atgctcgccg cctatcaggc
    11461 ctacgacgag agcgtcgtcg cctacagccc gtccgagggt tacctgacct atcggacagc
    11521 tctcgccgag cactacaacg gcctcgacgc cgcgcgcggc ggcggcccca tcactcccgg
    11581 ccagatcctc gtcaccgtcg gcggcagcga ggcgctgctg ttcgccatcg ccgccgcctg
    11641 cgacgtcggc gatcagatcc tcgtcgccga gccttactac accaactacc gcggcttctc
    11701 gcacatcctc ggcgtcgacg tcgtgcccgt ctcgacccac gcgcgcgaga gcttcgccgt
    11761 cccgcccgag cgcgtgcgcg ccgcgatcac cccgaagacg cgggccttca tcatcccgtc
    11821 gccgggcaac ccgaccggca tggtgctgag cgccggcgac ctcgccgcgc tcggcgaggt
    11881 gtgcgtccag gccggcatct tcttcgtcgt cgacgaggtc taccgcgagt tcgtctaccc
    11941 cgaccagccg gtccccgccg gcgcaccggt gccgcgcgcg ccgtcagtgc tcgcagtgcc
    12001 cggcctcgcc gaccacgcgg tgatgatcga ctccgtctcg aagcgctact ccgcctgcgg
    12061 cgcgcgggtc ggctgcctcg tcactcgcaa cgccgcgctc tactcggcct gcctgcggtt
    12121 cgcccaggcg cgcctgtctc cgccgaccgt cgatcagtac gccgcgctgg ccgccctgcg
    12181 caccccggcc gccgacatgc gggccatggt cgacgagtac cgcgcccgcc gcgacctcat
    12241 cgtcgccggc ctcaacgcga tccccggcgt ctcctgcccc acgcccaccg gcgccttcta
    12301 tctcatcacc gatctaccgg tcgccgacgc cgaagacttt tgcatcttca tgctccgcga
    12361 cttcgacctc ggcggcgaga ccgtgatgat ggccccggcc gagggcttct acgccacgcc
    12421 cgggctcggc aagaaccagg tgcggatcgc ctacgtcctc ggccgcgaca agctcgcgcg
    12481 ttgcctcgag atcctgcgcg ccggcctcga cgcctacaac cgcgccgcgc gctgacctct
    12541 cgccgcagcg aactccgctg cgcgcctgca cggcgcgcgc cgcatcgatc cgcgcacgag
    12601 cggtcctcgt gcgcgccagc gcctcgcgcc ctcgcctgcc gcgcgcgcct cgttcgccgc
    12661 agtcatgcgc ctgcgacgcg gtccacccgc ggcgcgccca cgcgtctcac gacgacctcg
    12721 accgccagcc atcgccggtg cggcggaatt tccaggcctc gcgaccgcgc ggggtcctgc
    12781 ctcgcgcgtc cctggctccc cccccgatcg tccgccgcgc tgaaccgccc ggccacgccg
    12841 gacgcaaggc cggttacact ccacgcatga gcctcgtggc ccccacgccg ctcggcttcg
    12901 agcgcagtcc cgtcgccggc gccagcgtcg acgacctcga cctcgccgcg ctcgaggcct
    12961 acgtccgtcg tcgcgtccct ggcctcggca ccgagcccgg ggtgttcgag cgcgccgccc
    13021 agcggctcgg cctcatcggc accaccggcg gccagcccac gcccacggtc gtcggcctca
    13081 tggcctttgg gacagctccg caggtcgccc ggcccgagtg gggcgtctcg atcgtgcgga
    13141 tccgcggcgc cgccctggcc gacccggtcg ccgcccggct cgacgccgag ggcaacctcg
    13201 ccgagctcgt ccgcctcggc ctcgagttcg tgcgcgccaa cacccgcgcc gcgcccaacc
    13261 tcctgatccc gtccgacctc gcgcccgagt accccgagga ggccgtgcgc gaggcgctgg
    13321 tcaacgctct cgtccaccgc gactaccgcc tcagcggccg cgtctcgctg cggatcttca
    13381 acgaccgcct cgagatctgg agccccggcg gcctcgccct cccgatctcg ctcgacgagc
    13441 tggcccagca cggcggcgcc tcgttcccgc gcaacccgct gctggccgcc actgcccgcc
    13501 acctcggcct gctcgagcag atcggccgcg ggatcccggc catccgccgc agcatcgccg
    13561 gcgccaccgc cctccccgtc cagttccaca cctctcagac cgaggtccgc gtggtcctgc
    13621 cgtcgtacat caacgcctcg atgggcaacg tctccggcaa ctgaccgcct ggacatgccc
    13681 cagggcgcat gtcccgaggc ccatgctctc ggggacatgt cccatcccgc atgtctctcg
    13741 gctcaggacg ggccaaagcg cacccgcgtg accccggcag tgcgcgggtg accggcacca
    13801 tccagcgcgt cggcccgcac ccgcatcgtc gccacgactg cggcgtgttg tacctgcgat
    13861 cgcacgacaa gggtccggtc gaccggagac ggggccgcgc ggtcgcgtcg cggcagagag
    13921 cgatccgtct ccggccgacc ggaaattcgc ctcagaagca ctccgcctgg cacgactgcg
    13981 acgcgcaggc gctgagcgcg tggtagagcg cgtggccgtc gggatcgctg tggcacaccg
    14041 cgtcgtcgtg aaccgtgaag cagcccgtcc agcacacagt gttggcgtgg cagcccgcga
    14101 tctcgtcgca gcagttcgtg cccaggcagg tcgtgcacgc gtcctgcccg agctcggcca
    14161 gcgcgtcctc gcagctgccg accggcccgc cgatgcacgc ctcctgacac gccgcgccct
    14221 tgcactcgag gtacgcgtcg acgcgcgcgt gcgtgtccgg gttcgactcg cacgcctcgc
    14281 cgtcctcgcc tgacacacag gccaggcagc tcgcgtccgc ctggcagtcg gccagcgcct
    14341 cgcagcacgc ctcgcgcatg cagcccgtgc actcgtcggt ggcctcgccc gcgcacgcgg
    14401 cctcggtggt cgcggacgag gcggtcgtcg cagtcgagct cgccgccgtg gtcgcgtcgg
    14461 tcgtcggctc ctgcgtggtc gtcgtcgtcg tctcggcgct cgtgctcgcg gacgacgtcg
    14521 tcgcctcgga agtggcgccc gtctcgacgc cgctcgtcgt cgcaccgctc gtcgtcgcct
    14581 cggtcccgga cacgggggcc tcggtcgacg acgtcgattc ggcgccgcaa gcgagcgcgg
    14641 ccgcgaagac gaggaaggac agcggagatc gggcaggagc aggcatggtc atgtcggcca
    14701 cgatggttag aagtaatgat attcattttc aataaaactt ccaaccaccg atctatcgcc
    14761 acaaagttgc ctttctcatc caggatcatt gatactaatt ttcaaaacgc cgacgattct
    14821 ggttgccaat tttcgcctcg atcggccaac gcgcgcgcga ccccgggcgg ccgcgaggtc
    14881 gccagcgcgt cgccatgcga cgcggtggac gtcgtcgcct ccgcgttccg cgaaattttc
    14941 cgagcccgcg ccgcgccgcc gtcgcgcgcg cgaagtgagg tcgaggcggg cgcgcgcggg
    15001 ccgtttgcga cggtcccgcc gcgtcctccg cccgtccgcg tgcgctacac tgctcgtcgg
    15061 catgcagccc gacgaagagc tctacgtcgc ctggcggggc ggcgacagca aggccggcgt
    15121 ccagctgttc gagcgccact accccgcgat cgcccgcttc ttccgcaaca aggtggacga
    15181 cgacgccggg gacctcgtgc agaagacctt cctcgcctgt ctcgagagca aggagcggat
    15241 ccgcggcgac tcgagcttcc gcaccttcct gttcgcagtc gcccacaacg tcctctacaa
    15301 gcacctgcgc ggcaagctgc gcgagggggc gcgcctcgac ttcgggctca ccagcgtgca
    15361 cgacctgcgg ccgaccccgg ccaccttgct cgcgcggcgg cgagaggagc ggctgctcct
    15421 gctcggcctg cggcggatcc cgctcgatca ccaggtcctg ctcgagctct acttctggga
    15481 gaagctcggc gcgcgcgaga tcgccgacat cctgggggtt cccgagggca ccatccgcac
    15541 ccgtctgcga agggccaagc agctgctcga ggcggcgatg accgcgctgg aggacggcgc
    15601 ggccgagctg cgcgacagcc tcggcgacct cgacgcctgg gccgcggccg tccggggcca
    15661 gatcggctaa gaatcacagc gagcgcgcct cgatgtcgat ccacgccgtc cgtcgacact
    15721 tcaccacacc ggccctgcgg cggcggtggt tcgtcctcct cttcacgctc ggcctcacca
    15781 cccagccgct gttcggcgcg ctcggctacg agggcgcgct ggtcctcacc ccggtgatca
    15841 gcctgttcgc cctcgccgtc ggcgtcgacg cggtgcggga cacccggcag gcccacgcct
    15901 ccgatccgca cgccatgtcc ctgcagacct ccggcgagcg cctgaggctg ctgttcctgc
    15961 gcggcctcgg cgacctctgc agcctgctca cgctctcgct cggcgccttc atcctcgcca
    16021 acttctggca gatcaactgc gacctccccg gcggcctgct gtggttcctc gtcctgccga
    16081 ccgcctccgg cctgctcggc ctggtcgccg gcctgtgggg cggcgtcctg gcccaccggc
    16141 gcggcgtgca gctggcgctg gcgagcgtcc cgctcgtctt ctcgctggtc ctcggcctgt
    16201 ggcggatcta cgtcgacccg gtcgtctacg ccatcgatcc gttctggggc tacttcgccg
    16261 gcccgctgta cgacgaggcc atcccgatca ccgcccgcct gtggtggttc cgcgcctaca
    16321 acttcctcgt cgccggcgcc gccctggccc tgctcagcct gaccttgggg ccaggtctca
    16381 aagtacagct gcgcggcgtc agcctgcgtc gctcgccgtt caccgtcgcc gcgctgctgg
    16441 cctgcctgat gcccggcgcg ctgctcgggg tgttcgccgc cgagaacggc ttccacgcca
    16501 ccgaggccag cctggccaat gccctcccgc gcacccgcgt caccgaccac ttcgtcatcc
    16561 actacgccgc caactcggcc gccgcccgcg acatcgacct cctcgccgcc gagcacgagt
    16621 tcgcctggcg ccggctcgcc gcccagatcg gccgcgagcc gcgggtcccc gtccacagct
    16681 tcgtgttccc cacccccgag ctcaagcggg cctggatcgg cgccggcaac accgaggtcg
    16741 cgccgccgtg gcgcggccac atctacctca acgagcaggc cttcccccac cgcgtgctcc
    16801 accacgagct cgcccacgtg ttctcgtaca ccgtcggcga gccgctgttc ggcacctcct
    16861 cggcggtctc gtggcgcggc ctgcgggtca acctcgcgct gatcgagggc ttcgccaccg
    16921 cgttcgcccc gcgcagcgag tccggcctcg accttcacga ccaggccgcg atcctcgacc
    16981 ggctcgagct gcgacctgtc ctcggggaca tcatgggctt cggcttctgg ggcaagtcgt
    17041 cgcggcgggc ctacaccgcg gccggctcgt tctgccgctg gctcatcgac acccgcggcg
    17101 tcgagccctt cctccgcctc tacggcaccg cgggcgactt cgacctgtcc tacgggacat
    17161 ccctcgacgc gctcgaggtc gagtggctgg cgttcctgcg cgcgcggccg ctgcgggccc
    17221 gcgacgtcga ggcgctgcgc cagcgcttca agcagcggcc gatcttccag cgcccctgcg
    17281 cccaccgggc cgccgacctg ctggccgagg ccaacctcgc ccaccaccgc ggcctcgagg
    17341 tcgagcgcat cgacaccttg cgcgacctct gcagcatcga gcccgagcag cccgagcacc
    17401 gcctgctgct ggcccaggcc gaggcgcagg ccggcatgca ggacgccgcc gcggccaccc
    17461 tggccgagct gtcgcgccag aacgacctct ccgacacgat cgccgcgctg gtcgacgagc
    17521 gcctcggcga tctcgctctg gcccgcttcg acctcccggt cgcgctcacc tactacgacc
    17581 gcgcgctgac ccgcggcctc ggcgacaacc agatccgcca gctgcagatc aagcgcatgg
    17641 gcgccgccga tccggccctc gcgccgcgcg tcctggccta cttcgatccg ttcgagccca
    17701 accccgagca cccgagcgag gccgtcctgc gcctctacgc ggccgagcag atcgccgcgc
    17761 tgccgcgcta cgccccgctc ggcggctacc tcctcggccg ccagctgctc aacgtccagc
    17821 agggcgccgc cgcgatcgag ccgctgcagc gcgcgctcca ccccgaggag gacgagcacg
    17881 cgctctccac tgccgagctg cgccgcggcg cgcggctcat gctgctcgag gcccaggccc
    17941 gcgcccgcaa ctacgacgcc gctgcccgcg tcctcgccga gctgcaggaa gaccccgacg
    18001 ccgacagcgg tctgcgcctc gacgccgcgc tctggaccga gcgcctcgag ttcctccgca
    18061 cccacttgcc ctgaagacct cgacagcggc ctgcgccgcg accgagcgcc gcgggttcct
    18121 ccgcaccgac tgtcccatgg gacaggtttt ctcaccaggt ctcgacgggt tcgcctacgg
    18181 cctggaactc gacgccgccc tgtcgaccga gcgcctcgag ttcctccgca cccacttgcc
    18241 ctgaagaccg cgacagcggc ctgcgccgcg accgggcgcc tcgagttcct ccgcaccgac
    18301 tgtcccatgg gacaggtttt ctcaccaggc ctcgacgggt tcgcctacgg cctgggcctc
    18361 gacgccgccc tgtcgaccga gcgcctcgag ttcctctgca cccacttgcc ctgaggtgtg
    18421 cgtccccgcg gtcaccgacg tgtcccttca gacaggtcgt cccggcatcg cccgacacga
    18481 ttgcccgggc cctcgccgag gtgtcgcacc acgaccccgc acaggcccgc ggaccggtcc
    18541 gccaggctcg gaccgcgatc ggacatcggc ccagttgcgc cagttattct tcaaaaacta
    18601 ccattcgttt tatttctttt ggcaaaaaca tggggcacaa tgaagacgag atgtcagttt
    18661 cacgccgtac gcgcaccgcc accatcgcgc gactttgtgt ctggaccggc ctgttcgtcg
    18721 ccgccgcgac gcacctgacg gtcgagccga gccgcgtctc cgccaacccc gaaccggccg
    18781 cccgcgtcga gccgctgaag cggcccctcg cggctgccga agaggacatg tccttaaggg
    18841 cagcctttga agccgccggc gcgatcgccc tgtcgacccg gccctatccg acctgcccct
    18901 tcgaccaggc gtgcgactcg cccgacgagg ccgctcgctg accgcaggac cgttcggaca
    18961 tgtcccgaag ggcaaccgcg ctcctcctcg cctgcgcctg cgtccccgcc gccgacgccc
    19021 cggggacgag cgcgaccgac accatcatca ccacgagcat cgccaccacc ggcaccaccg
    19081 ccacgacctc ggcggcgccc acgacgacga ccgcgacgag cacgagcgag gccctgacct
    19141 cgggcggcgt caccttcatc cagccgcccg acggcggcgg gagcaaggag tgcgacctct
    19201 tcgagcagga ctgtcccgag ggcatgaagt gctccccgca ctccgccgac ggcgacaacg
    19261 cctgggagac cctgaaatgc gtcgacgtcg tgcccgctcc ggccggattc cacgagccgt
    19321 gccagcttct cggcgtccct gccagcggcg aggacacctg cgacgagggc ctgatgtgct
    19381 ggttcacgca gtcggacacc ggcgtgggca tctgcctgcc ccactgcacc ggctcgcccg
    19441 acgcccccgt ctgcgccccc ggcagccgct gctcgagcac cttcccgggc gaggacatcc
    19501 tcagcctgtg cctcccctcc tgcgaccccc tcgcgcagga ctgccccaac ggcgggccct
    19561 gcaccccgtg ggacgaggag ttctggggct gctattccga cgacagcggc gacgagggtc
    19621 aagccttcga cccgtgcgtg cacgtccggg cctgtgatcc cggcctgacg tgcgccgagc
    19681 ccgagctcgc cgacgagtgc gatccgcggg cgaacggctg ctgcctgccg tactgcgacc
    19741 tcgacctccc gaacacctgc cccggccagg gccaggcctg cgtcgcctgg tacgtgcccg
    19801 gccaggcccc gcccggcctc gaagacgtcg gcctgtgcgc cctcccgtga ccacgcacga
    19861 gcgaccgcca cctctatctg ctccaaaaaa catgtcctga aggacatgac cttatcacca
    19921 cctgcacctt tcaccaggac cgaccctcat gtctcgtcgc ccgcgcgtcc tcctcccgct
    19981 cgtcctcgcc gcctgcgtcg cccgccccac cggggacacc gacgacgcgc ccaccggcgg
    20041 gcccgcgacg accaccaccg gcgatcccga gcccggcacc tccgggggca ccacgacggc
    20101 gtcgaccacg gctcccggga cgaccctgcc gccgcccacc accaccgatc ccacgaccgc
    20161 gttccccacc accggcgagc ccgctccgac caccgaggcc ctcaccacca cgccgttcct
    20221 ccccgcgccg gacttcagca accccaacga gtgcgacccg tggatcgagg actgtcccga
    20281 aggacagaaa tgcatggcgt gggccagcga cggcggcagc agctggaact ccaccaagtg
    20341 cgtcgacatc gtcccggacc ccgacggcct cggtgagccg tgcagcgtca tcggctcgcc
    20401 cgtcagcggc gaggacacct gcggcaagca cctgcagtgc ttcttcgccg accccgacac
    20461 cctccagggc acctgcctcg ccatgtgcgt cggctcgccc gacaatcccg actgcgagca
    20521 gcccgacgcc acctgcgccc tctcgggcga cggcgtgctc atcctttgcg tgccagactg
    20581 cgacccgctc gcgcccgact gcggacccgg cgaggtgtgc gtctccaaca acggctcgaa
    20641 cttcacctgc gtcttcgacg ccagcggcga cgagggccag ctgttcgacc cgtgcgagtt
    20701 catcaacgcc tgcgacccgg gcctcgcctg cgtgaactcc gagctggccg gcgagtgcga
    20761 ccccgacgtg ttcggctgct gcctcccgca ctgcgacctc accgccccgc cgtcgtgccc
    20821 cggcgcgggc caggagtgcc tgccgtggtt cgagcagggc caggccccgc ccggccacga
    20881 ggacctgggc gtgtgcggcc tgccaccgcc ctagcctttc gaacaggtcc gattcaccat
    20941 gtcctatcca tcatgtccct atgaatatgt attgacgacc atgtccgaat ctacatgtcc
    21001 ttctcgccgc gcccccgacg gcccggcgac tggaactacg gagtttatcg ccatgtccac
    21061 ccgaattctc gcgctccccc tcttcctcct gctcgcctgc ggccccaagg tcggcgaaga
    21121 caccgacggc ccgcccgtcg gcagcg
//
