LOCUS       NZ_CP114040            21900 bp    DNA     circular CON 26-AUG-2024
DEFINITION  Nannocystis poenicansa strain FL3 chromosome, complete genome.
ACCESSION   NZ_CP114040
VERSION     NZ_CP114040.1
KEYWORDS    RefSeq.
SOURCE      Nannocystis poenicansa
  ORGANISM  Nannocystis poenicansa
            Bacteria; Myxococcota; Polyangia; Nannocystales; Nannocystaceae;
            Nannocystis.
REFERENCE   1  (bases 1 to 13228663)
  AUTHORS   Ahearne,A., Stevens,C. and Dowd,S.
  TITLE     Minimal conservation of predation-associated metabolite biosynthetic
            gene clusters underscores biosynthetic potential of Myxococcota
            including descriptions for ten novel species: Archangium lansinium
            sp. nov., Myxococcus landrumus sp. nov., Nannocystis bai
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 13228663)
  AUTHORS   Ahearne,A., Stevens,C. and Dowd,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-NOV-2022) Biomolecular Sciences, University of
            Mississippi, Faser Hall 407, Oxford, MS 38655, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2021
            Assembly Method                   :: IPA v. 10.1.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 250x
            Sequencing Technology             :: PacBio Sequel IIe
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_026965555.1-RS_2024_08_26
            Annotation Date                   :: 08/26/2024 12:45:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,229
            CDSs (total)                      :: 10,129
            Genes (coding)                    :: 10,068
            CDSs (with protein)               :: 10,068
            Genes (RNA)                       :: 100
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 9 of 61
            Pseudo Genes (incomplete)         :: 52 of 61
            Pseudo Genes (internal stop)      :: 2 of 61
            Pseudo Genes (multiple problems)  :: 2 of 61
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:28:22
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5487560
            Orig. end                         :: 5509460
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP114040.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21900
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="17"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21900
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21900
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11900](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11900)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    888..897
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            1175..2734
                     /gene="cobA"
                     /locus_tag="O0S08_RS21200"
                     /old_locus_tag="O0S08_21200"
     CDS             1175..2734
                     /EC_number="2.1.1.107"
                     /GO_function="GO:0004851 - uroporphyrin-III
                     C-methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0019354 - siroheme biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cobA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TP_methylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF004790.0"
                     /locus_tag="O0S08_RS21200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_21200"
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="WP_269041018.1"
                     /sec_met_domain="TP_methylase (E-value: 1.9e-43, bitscore:
                     148.1, seeds: 87, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGFVSIVGAGPWDPELLTLAGRERLTRADVVIADYLVNPALFTH
                     CRADVHLFQRTESPHAGAHGEPVPDQEAINRLMVERAAAGLYVVRLKGGDPMVFGRGAE
                     EAEVLAARGIPFEFVPGVSAAIAAPEAAGIPVTHRDHAPCVSLVSGYEAYEKGGRAVDW
                     EHLAKGTGTLVLMMSVRNCRQNAERLIAAGRDPATPSAVIRWGTRGIQRTVVAPLGQIA
                     DRVEAEGLRPPAVMVVGSVVDLRRTTQWFERRPLFGKRVVVTRARQQASDLLQLLAGQG
                     ADAVAVPCLDIAPPEDLSALSGAAQSLDEVDGVILSSPNGVRAWFDALAGLELDVRALH
                     GKCLAAIGTGTANACWERGIRPDIVPSAARSEGLVETLASRGLLARRWLHVRADEGRDL
                     IGEAVRAAGGTYRLVVGYRVIRPKVPGLLTRSLLPPEHGGEGTDAICFASGKTARHFVE
                     TITEAHGEALAREILGRARLVALGPVTAGALESMGLRADAVAGGLTDEAMLAAVVEAMA
                     RG"
     misc_feature    complement(3061..3074)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.8"
                     /tool="antismash"
     gene            3103..4353
                     /locus_tag="O0S08_RS21205"
                     /old_locus_tag="O0S08_21205"
     CDS             3103..4353
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.5"
                     /locus_tag="O0S08_RS21205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_21205"
                     /product="cytochrome P450"
                     /protein_id="WP_269041019.1"
                     /sec_met_domain="p450 (E-value: 2.8e-12, bitscore: 45.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSFLREYAASEAGARTAVTLRWLAGRPRELFVELQREQPIFSTPS
                     FVLLTRYAEALEVLTRGDVFLGHALEARRQPLFGGFSLDEREGPRAAVEAALVRLCVRG
                     EDAERVATISHEAATAAVSAGRRAGRFDVVRDLAHVVAGRVAAEYLGVGGPEESTLVRW
                     VEAIGRDIEDNPTDDSEIHEEARAAAAELGGYTDTMVASRRAQRSSGRMAGDDVLGRLV
                     ALQNVAHLRLEERRLREVLLGLLVAGIEPIACSIGLALGELIDRPEALRMARAAAKAGD
                     DDGLWAVLREALRFSPPRLTVSRICGEDYTLAKGTANEVVLHAGVTVVVATAAAAFDPE
                     RVDDPEHFRLHRPDHHDFLFGEGPHGCLARQVAIAAVREGCKALLGHEFRLSGPLRRDG
                     GRPIAFPVALGPLRAVG"
     gene            4878..5441
                     /locus_tag="O0S08_RS21210"
                     /old_locus_tag="O0S08_21210"
     CDS             4878..5441
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011552939.1"
                     /locus_tag="O0S08_RS21210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_21210"
                     /product="bacterioferritin"
                     /protein_id="WP_269041020.1"
                     /transl_table=11
                     /translation="MTTGQSSFSTDIATIRKRAREHLEQGALTPNYGADVETAIRVLNE
                     ALATEIVCVLRYRFHAVTATGIASESVKAEFEEHAQEEEAHMLWIAERINQLGGKPNFN
                     PDGLSSRSASQYVEGKNLVDMIKEDLVAERIAIETYREMIRYFAEHDPTTRMLLEKILA
                     QEEEHANDMHDLLVAHEGKPMLDH"
     gene            complement(5733..6152)
                     /locus_tag="O0S08_RS21215"
                     /old_locus_tag="O0S08_21215"
     CDS             complement(5733..6152)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS21215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_21215"
                     /product="hypothetical protein"
                     /protein_id="WP_269041021.1"
                     /transl_table=11
                     /translation="MHEALLLHSREAFQVWLAGDVEVRDELYALIGEPLGTDLESLDTL
                     ESFLLARYRRPNQILKIGEREILDAAARHIGLVMLLNLDDAAWAIELDDEDNVYYRLPI
                     IRLADGAEECPLTMVTAALDRRKRSYLRGVVESYA"
     gene            complement(6316..6675)
                     /locus_tag="O0S08_RS21220"
                     /old_locus_tag="O0S08_21220"
     CDS             complement(6316..6675)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS21220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_21220"
                     /product="hypothetical protein"
                     /protein_id="WP_269041022.1"
                     /transl_table=11
                     /translation="MSIAFEELLTPRGRPYVRVTVAGEFGLTEAEQFVQRFGKDGPYYM
                     KPSMSVVPRGTEYTTEARKHLQTMGEAGPTCTVTSSPLVRAAINLMLRLSGRPNTLRLC
                     GTESEALAWLDERLS"
     gene            complement(7152..8414)
                     /locus_tag="O0S08_RS21225"
                     /old_locus_tag="O0S08_21225"
     CDS             complement(7152..8414)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_DAP_Arg_deC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264: diaminopimelate decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020740106.1"
                     /locus_tag="O0S08_RS21225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_21225"
                     /product="diaminopimelate decarboxylase"
                     /protein_id="WP_269041023.1"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 1.5e-43, bitscore:
                     148.2, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 2.5e-07,
                     bitscore: 30.1, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPIAVDARPAPEQLAEAFRRVRAAGHADEPAVLVHDLDRLRAKLA
                     DVAAAFAGPRALHTVAIKANPLVGVLRVAVAAGAGLEAASIEEVHLALRAGCSPDRIVF
                     DSPVKTEAELAEALRMGLRINADNFAEIERIAALHTPACASRIGLRINPELAEAAIALT
                     SVGHRGSRFGVPLSQHSAIVEAFARHRFLTGLHVHIGSQGVTIPELVDGVARVWQLRRE
                     LVAVRPVPLDMFDLGGGLPAQYRDDAPRLTPTAYAAALRAAVPDLFRGDVQLVTEFGRS
                     ILADCGFVVSRVEVVKPGPVAGLHVGADLFVRRVYRPHEWHHDFLAIGRDGLPLAGDPV
                     ATTLAGPLCFGGDVLARDLPLPALAPGDHVLIRDTGAYTLSMWSRYCSRAIPAALGLDG
                     DAVTVLRPRDTIADVVAFWGG"
     gene            complement(8573..9925)
                     /gene="hpnE"
                     /locus_tag="O0S08_RS21230"
                     /old_locus_tag="O0S08_21230"
     CDS             complement(8573..9925)
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR03467.1"
                     /locus_tag="O0S08_RS21230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_21230"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_269041024.1"
                     /sec_met_domain="DAO (E-value: 6e-13, bitscore: 48.3,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSESTRSVIVIGGGLAGLSAAVRLAEAGRVVTLIEATRAGGGRAR
                     SFHDATLDREVDNGQHLMMGCYRETLAFLRAIDSTDGVYFQKNLEVTMVKPGGKRLHLQ
                     CPALPAPLHLATGLLTMRGLGVLDKAAALRAGLMLRGEVQRPDDNETCDSWLRRLGQTA
                     TLRNAFWDPLIWGTLNDDPLVSSAAMFTAVLDRAFLTSRDASRLGVPKVPLSRLYVEQS
                     LAYLRARGCELRLGEPVRALEVVNSRVTGVTLKSGDTLAADVVVSTVPPQAFLDMLPGT
                     LPNHPVYQDIARLRPSPIVNLWFSVDRAPFEDPFVGLVAGPLHWMFNRSQIEGEVGSEV
                     MMNCTISAARACVDDPPETLQALLQSELQRYFPAAGPQGPKIKRFKVIKEKRATISHAA
                     GTYHCRPEVTGPVRGLYMAGDWVRTGLPATIESAVQSGHDAAKAILTSERN"
     gene            complement(10001..10906)
                     /locus_tag="O0S08_RS21235"
                     /old_locus_tag="O0S08_21235"
     CDS             complement(10001..10906)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012705.5"
                     /locus_tag="O0S08_RS21235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_21235"
                     /product="squalene/phytoene synthase family protein"
                     /protein_id="WP_269041025.1"
                     /sec_met_domain="phytoene_synt (E-value: 4.4e-51, bitscore:
                     172.9, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.8e-67,
                     bitscore: 226.3, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELARTIPSGAVALWRRLVQRSNSNFKFAFLFLGPEQREGLQQVY
                     EFCRVVDDIVDEREPGPAGEEAARRALAGWSAEVARIYGDAYVDDDPPHTELGRQLAES
                     NKHFHYPRDAFDEIIAGVAMDLDRNTYDDMEQLRLYCYRVASCVGFLCLALFKDQREPA
                     RRYAEHLGLALQYTNILRDVAEDAARGRIYLPLELLARHGLTPDDVFNYRYDGRFVGAA
                     ADFAAAAEREYHAAWALLPEIQQRRLLPAEIMGRTYYEILQEIRARNYNVFTRRASLRR
                     RDKLRVAFLALARAGASVLS"
     gene            complement(10926..11900)
                     /gene="hpnC"
                     /locus_tag="O0S08_RS21240"
                     /old_locus_tag="O0S08_21240"
     CDS             complement(10926..11900)
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03464.1"
                     /locus_tag="O0S08_RS21240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_21240"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_269041026.1"
                     /sec_met_domain="phytoene_synt (E-value: 2.2e-57, bitscore:
                     193.6, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 5.1e-55,
                     bitscore: 186.0, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSATEPRLFCVPPPPEGDLEGQRVSSPDGAPPGPWTLETAYRYC
                     ERMATTHYENFPVASRFLPAHLRPNIMAIYAFARTADDFADEPRFESRRVDALDRWEQL
                     LVAAYHKEIQHPVFLALRDTVRRHNIPIGPFKALLTAFRMDLTQKRYGMFAELRHYCKH
                     SAHPVGQLVLYVHGHHEPELHRFSDEICAALQIANFLQDLSVDTPRGRCYLPEEDLVHF
                     NVTREDLLAARHTRAFKELMAFSVSRCRSMFLRGYPLVRRVEPGLSMELEATWRGGMAI
                     LQRIEDLDYEVLGFRPTLEKQDMLGIAARSIFSFGRRFLRGEV"
     gene            complement(12022..14280)
                     /locus_tag="O0S08_RS51090"
     CDS             complement(12022..14280)
                     /EC_number="1.1.1.88"
                     /GO_function="GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA]"
                     /GO_function="GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1187: hydroxymethylglutaryl-CoA reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR00532.1"
                     /locus_tag="O0S08_RS51090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hydroxymethylglutaryl-CoA reductase, degradative"
                     /protein_id="WP_276082613.1"
                     /transl_table=11
                     /translation="MTRLAVSAPGKAFLIGEYAVLAGATALVTAVGRRAVAADCDDPDR
                     PPASALTEAAYAHVRQFLSESTGTKAPGPLTSVDTGSFAAGARKLGLGSSAAAVAAVVG
                     FHLAEAGHDLEDPAVRAIALRLAQAAHAQVQGGGSGADVACAVLGGTIAFTRGEAPVPV
                     AHPAWLHIGFFDAGAPADTASFVQQVRAAGERDPAAHAAATAQLRRAAELFRGGYDSTD
                     ADVGLTAIRDAVALHNDGLRALQRLSDAPIVTPTIATIVDQAARMGLAAKPSGAGGGDL
                     VVVFAARQADLDLLAERLHREHGLAAIGRLPVAAPGLRRDERPPLSSRMSGFFRLGVDG
                     RRDAVAAATHIPRDRFAALDPGSLDLGSADNLIENVIGTLELPLAVATNFRINGRDFLV
                     PMAVEEASVVAAASNAAKMIRAGGGFFARSDPPWMIAQVQLTAPRAGEPAPQPAVAAIH
                     AARGDLLALADSAHPRLVARGGGARDLLVRVLAPDMLVVDVVVDCQDAMGANLLNTIAE
                     VLAPRLSDMTGWTAGLRILSNLADRRRAHVTCRVPPGALAGRGFSGAAAAAGIASASRF
                     AELDPYRAATHNKGVMNGVDAVALATGQDWRAIEAGAHAYAGLTGAYRPLATWRLDPEG
                     WLCGAISLPAAVGVVGGATKVHPAARLALEILGATSGAELGQVMAAVGLASNLAALRAL
                     ATEGIQRGHMSLHARSVAVGAGAQGAEVDLLVHRLVESAEIKHDRAVLLLHELRSESR"
     gene            complement(14277..15272)
                     /gene="mvaD"
                     /locus_tag="O0S08_RS21255"
                     /old_locus_tag="O0S08_21255"
     CDS             complement(14277..15272)
                     /EC_number="4.1.1.33"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /gene="mvaD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006927967.1"
                     /locus_tag="O0S08_RS21255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_21255"
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="WP_269041027.1"
                     /transl_table=11
                     /translation="MKSARAVAHTNIALVKYWGKRDSSPPDLNLPAVGSLSLTLDRLRS
                     ETTVCPGDQDSFHLNQEPASGEVAAKVMRQLDRVWQAAGHAGPRPACAVASHNYLPTAA
                     GLASSASGFAALTLAAAAAFDYEPGRPALSALARRGSGSAARSLWGGFVRLERGVLPDG
                     SDCRAYPLQPQSHWDVRLLIVHTERGPKAIGSTAGMQRSRDTSPYYGPWVDTSEADLAA
                     AEAALAARDLAVLGDILEHSCFKMHACMMASRPPIVYWRGATLDVIHAVWRLRAEGLRG
                     YVTSDAGPHVKVLCAADQADELAVRLRGVAGVHAVDVVGPGPDPTVEVFA"
     gene            complement(15269..16192)
                     /gene="mvk"
                     /locus_tag="O0S08_RS21260"
                     /old_locus_tag="O0S08_21260"
     CDS             complement(15269..16192)
                     /EC_number="2.7.1.36"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004496 - mevalonate kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016126 - sterol biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /gene="mvk"
                     /inference="COORDINATES: protein motif:HMM:TIGR00549.1"
                     /locus_tag="O0S08_RS21260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_21260"
                     /product="mevalonate kinase"
                     /protein_id="WP_269041028.1"
                     /transl_table=11
                     /translation="MSIPLHPRAEAHGKVIVLGEHAVVYGYPAVAAGLPQGIVLEARPR
                     PDPRLPITLTVPAWDLDLELHAGSDHPVARACLEVLAHCDGPVTGWAIHGTSALPSRAG
                     LGSSAALTVALARLVFGPDAGVDDVVAASLAGERVFHGEPSGLDSRVAAQGGVLRYVRG
                     EPPRSINPGAPLPLCIIPSGIPRSTADQVARCRSRLEHLPSVVRPVLIAIGQAVESGIH
                     AIEHGDLDTLGVLFDVAHGLLGALDVSSPALDRMAADARAAGARGAKLTGAGCGGCLLA
                     LAGDAPDRLTAAFPSLRPLFVEVAAS"
     gene            complement(16189..17253)
                     /gene="fni"
                     /locus_tag="O0S08_RS21265"
                     /old_locus_tag="O0S08_21265"
     CDS             complement(16189..17253)
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fni"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006970436.1"
                     /locus_tag="O0S08_RS21265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_21265"
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_269041029.1"
                     /transl_table=11
                     /translation="MADRLDISQRKKDHLALCAGDNVGFRDKTSLLEQVELVHDALPEM
                     HLDDIDSSVELLGKRLRAPVVIAAMTGGTEEAAVINQDLARAADQLGLGFGLGSQRAMF
                     VRPHTAHTFKVREQAPNVLLLGNLGIVQARAMTTAEIATLCRDTGADALCIHLNPAMEI
                     VQPGGDRDFSRGLDTLRRLVEELHIPVVAKETGCGLSRGVAERVRSVGVEHLDVSGSGG
                     TSWVAVEAHRAVDPDERALADELWDWGIPTAASVLQVQGLGFRGIVATGGLRTGSDVAR
                     AVALGATAGGLAAPVLKAHRAGGYDGVVAFLRRVVLTVRSIMLLTGSRTVADLQRAPRV
                     LGPTLARWVPEPRR"
     misc_feature    17238..17252
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     misc_feature    complement(17376..17391)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.8"
                     /tool="antismash"
     gene            18105..19226
                     /locus_tag="O0S08_RS21270"
                     /old_locus_tag="O0S08_21270"
     CDS             18105..19226
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS21270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_21270"
                     /product="hypothetical protein"
                     /protein_id="WP_269041030.1"
                     /transl_table=11
                     /translation="MLWLAACSSAKEPGETATEGSGNPSGDPTGGGQGHAACEKYLACV
                     AVVLPSELPDAEAGFGQAGTCWQSTPEIAQGCVDACESGLVAFAMMYPNEPACGGSGMG
                     TTGTTESPTTTEGTTTEGTTTEGTTTEGTTTEGTTTEGTTTEGTTTEGTTTATTDTSAG
                     PMTTDIGPCEDLPLQPDGATCTQPSGCGCSSGKCFVYPVFGGYCGECLVDADCDGGGCT
                     GPNPFTGPGAVCNDGGPGDGCQSDAVCSDPNNGVCAAVIEVPGIITVSTCGECQTDADC
                     SAPTPVCAPKYDVADFSGRFDCVAKGSVANNGGCNSDAACASGHCGAASLMGLVQFGVC
                     GECLTDADCSPGEQCVEGEADLGGGKLTGATCE"
     gene            19760..20167
                     /locus_tag="O0S08_RS21275"
                     /old_locus_tag="O0S08_21275"
     CDS             19760..20167
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019498.5"
                     /locus_tag="O0S08_RS21275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_21275"
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="WP_269041031.1"
                     /transl_table=11
                     /translation="MHLTQRLPNGVTVYKWPHNVEPTAESVAAEMARFGFRSYDLQTVP
                     PWFFRSRHAHDEEEIRGAVSGVTTFHFDEGPVTLEAGDILIIPSGVQHEVRSHNGRTFS
                     AYKGSRSGERHVTEHGDGRGSVEDLAGGGKS"
     gene            20164..20814
                     /locus_tag="O0S08_RS21280"
                     /old_locus_tag="O0S08_21280"
     CDS             20164..20814
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024811.5"
                     /locus_tag="O0S08_RS21280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_21280"
                     /product="HAD family hydrolase"
                     /protein_id="WP_269041032.1"
                     /sec_met_domain="HAD_2 (E-value: 2.3e-25, bitscore: 88.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSHLIALDLDGTLEDSRDDMVAAVLRVRASFGLSEQPGDTYRPYV
                     NAGMDHLYRSCFKEYVGAGGTVDDVRAAYEADYLAHIADTTRLYPGMGDALVELAALGS
                     LACVTNKPQRLSAALLEALGVGRLFSAVIGGDTCPESKPSPMVLAEASRRVGRTGAALM
                     IGDSAADVKCGRSFGATTIWCAWGYAADPGAETPDHRAATPLDLPRLVRSLVA"
ORIGIN
        1 gcaggcaggc tggtcgagat cccgccggga tagacgctgt gggtgtcgag gccctcgggc
       61 tcgaggaaga tctggtggcg ctcgcgctcg gcgaagcgga cgatcttgtc ctcgagcgag
      121 gggcagtagc gcgggccgcg accgacgacc tggccgctgt acatggcgga gcggtgcaag
      181 ttggcgcgca cgagctcgtg ggtggcctcg gtggtccagg tgatccagca cgggacctgg
      241 gcgaggaccg gcggcgggcc gtcgtcgggc aaggtgaagc gcggcagcgg gtcctcgctc
      301 ggctgctcct cggtgcgcgc gtagtcgagg gtgcggccgt cgagccgcgc gggggtgccg
      361 gtcttgagcc ggcgcaggga gaaaccgagc gcgcgcaggt gctccgacag ggccagggcg
      421 ggcggctcgc cgacgcggcc gccaggggtg gtgcgctcgc ccgtgtgcag gaggccgccg
      481 aggaaggtgc cggtggtgac gacgacggcg tcgccggcga cgacggagcc gtcctcgagg
      541 acgacgccgc gggcccgccc ggcctcgaga tggacggcgg cgacgaggcc ctcgaggacg
      601 cgcacctgcg ggtggcccag gagggcggcg cgggcaaatt cgccgtagcg ggccttgtcg
      661 acctggaccc gggtgctgcg cactgccggc cccttggagc ggttgaggac gcgcccgtgg
      721 atcgcgcagg cgtcggcggc ccggcccatg aagccgccca tggcctcgat ctccttgacg
      781 aggtgaccct tggcgacgcc gccgacgctg gggttgcacg gggtctggcc gatcgtcttg
      841 aggctgccgg tgacgacgag gacgctcgca cccacccgcg ccgcggcgaa ggcggcctcc
      901 agcccggcgt gtccggctcc gacgacgatg acgacgggtt ccacggcggc gggagggtag
      961 cagacgatgg tgggggtcaa agcagagggc gaggtcgggc aggcggcttg cgcgggttcg
     1021 cgcatcgtgg tatgggggcg gcgtagctgg ctggagcggg ctggtgcgtg ctcggcggag
     1081 cagctgattc gtaatcagca ggtcttcgct caggagggcg cgttcgcgcg cgtccttgga
     1141 gccatttgcc cgcgggtggg ctatcttggc ggacgtgacg ggcttcgtct cgatcgtcgg
     1201 cgccgggccc tgggacccgg aactcctcac cctggcgggt cgcgagcggc tgacccgcgc
     1261 ggacgtggtg atcgcggatt acctggtcaa cccggccctc ttcacccatt gccgcgcgga
     1321 cgtccacctg ttccagcgca ccgagagccc gcacgcgggg gcccacggcg aaccggtgcc
     1381 cgaccaggag gcgatcaacc gcctgatggt cgagcgcgcg gcggccgggc tgtacgtggt
     1441 ccgcctcaag ggcggcgacc cgatggtgtt cggccgcggc gcggaggagg ccgaggtgct
     1501 ggcggcccgc gggatcccgt tcgagttcgt gccgggcgtc agcgcggcga tcgccgcgcc
     1561 cgaggcggcc gggatcccgg tgacccaccg cgaccacgct ccctgcgtca gcctggtgtc
     1621 gggctacgag gcctacgaga agggcggtcg cgcggtcgac tgggagcacc tggccaaagg
     1681 gacaggcacg ctggtgctga tgatgagcgt gcgcaactgc cggcagaacg cggagcggct
     1741 gatcgcggcc gggcgcgacc cggcgacgcc gtcggcggtg atccgctggg gcacccgggg
     1801 gatccagcgc accgtggtcg cgccgctggg ccagatcgcg gaccgcgtcg aggcggaggg
     1861 gctgcgcccg ccggcggtga tggtggtcgg cagcgtggtc gacctgcgcc ggacgacgca
     1921 gtggttcgag cgccggccgc tgttcggcaa gcgggtggtg gtgacgcggg cccgccagca
     1981 ggcgagcgac ctgctgcagc tgctggccgg tcagggcgcg gacgcggtgg cggtgccgtg
     2041 cctcgacatc gcgccgcccg aggacctgtc ggccctcagc ggggcggccc agagcctcga
     2101 cgaggtcgac ggggtgatcc tgtcgagccc gaacggagtg cgcgcgtggt tcgacgcgct
     2161 ggcggggctc gagctcgacg tccgggcgct gcacggcaag tgcctggcgg cgatcggcac
     2221 cggcacggcg aatgcgtgct gggagcgcgg gatccggccg gacatcgtgc cgtcggcggc
     2281 gcgctcggag gggctggtgg agacgctggc gtcgcgcggg ctgctggcgc ggcgctggct
     2341 gcacgtgcgc gccgacgagg gccgcgacct gatcggggag gcggtgcgcg cggccggggg
     2401 gacgtaccgg ctggtggtcg gttaccgggt gatccggccg aaggtgccgg ggctgctgac
     2461 gcgctcgctg ctgccgcccg agcacggcgg cgaggggacc gacgcgatct gtttcgccag
     2521 cggcaagact gcgcgccact tcgtcgagac gatcacggag gcccacggag aggcgctggc
     2581 gcgcgagatc ctgggccggg cgcggctggt cgcgctgggg ccggtgaccg cgggggcgct
     2641 cgaatcgatg ggcttgcgcg cagacgcggt cgcgggcggg ctgaccgacg aggcgatgct
     2701 ggcggcggtg gtcgaggcga tggcccgcgg gtagcgcggg cgtggcgacg agcgatgtcg
     2761 gcggcggggc gccgcggtgg cgagtgatgc tgtcggggcg aggcgccggg gtcgcgcgat
     2821 gctgtcgggg cgaggcgccg gggtcgcgcg atgctgtcgg ggcgaggcgc cggggtcgcg
     2881 cgatgccggc gaggcgaggc gacggggtcg cgcgatgccg gcgaggcgag gcgacgggct
     2941 gcgggtcgcg cgggaccggt gcgacgaggc gagccgcggg tcgtgcgggg ccggcgttcg
     3001 cgggcgcgca agcgggcgcg cggggggctc tcgggggctc tcgggcgaag gacgagcggc
     3061 cgagcgtttg tccgttgccc ggcgggccgg tatcgtcggg cgatgagctt tctccgcgag
     3121 tacgcggcga gcgaggccgg ggcgcgcacg gccgtgacgc tgcggtggct ggcggggcgc
     3181 ccgcgcgagc tgttcgtcga gctgcagcgc gagcagccga tcttctcgac gccgagcttc
     3241 gtgctgctga cccgctacgc cgaggcgctc gaggtgctga cgcgcggcga tgtgttcctg
     3301 ggacatgccc tcgaggccag gcgacagccg ctgttcggcg ggttctcgct cgacgagcgc
     3361 gaggggccgc gggcggcggt cgaggcggcg ctggtgcggc tgtgcgtgcg cggcgaggat
     3421 gccgagcggg tggcgacgat cagccacgag gcggccaccg cggcggtctc ggccgggcgc
     3481 agagccggca ggttcgacgt ggtgcgcgac ctggcccacg tggtggcggg acgcgtggcg
     3541 gccgagtacc tcggggtcgg cgggccggag gagagcactc tggtgcggtg ggtcgaggcg
     3601 atcggccgcg acatcgagga caacccgacc gacgacagcg agatccacga ggaggcccgc
     3661 gcggcggcgg ccgagctcgg cggctacacc gacacgatgg tggcctcgcg ccgggcccag
     3721 cgctcgtcgg ggcgaatggc cggcgacgac gtgctggggc ggctggtggc gctgcagaac
     3781 gtggcgcacc tgcggctcga ggagcgtcgc ctccgcgagg tgctgctggg gctgctggtg
     3841 gcggggatcg agccgatcgc gtgctcgatc gggctggcgc tcggcgagct gatcgaccgc
     3901 cccgaggcgc tgcggatggc tcgcgcggcg gcgaaggccg gcgacgacga cgggctgtgg
     3961 gcggtgctcc gcgaggcgct gcggttctcg ccgccgcggc tgacggtgtc gcggatctgc
     4021 ggggaggact ataccctggc caaagggaca gccaacgagg tggtcctgca cgcgggggtg
     4081 acggtggtgg tggcgacggc ggccgcggcg ttcgacccgg agcgcgtcga cgacccggag
     4141 cactttcgcc tgcaccgccc cgatcaccac gacttcctgt tcggcgaggg gccgcacggg
     4201 tgcctggccc gccaggtggc gatcgcggcg gtccgcgagg gctgcaaggc gctgctcggc
     4261 cacgaattcc gcctgtccgg gccgctgcgc cgcgacggag ggcggccgat cgcgttcccg
     4321 gtcgccctgg gcccgctgcg cgcggtcggg tgagaccgcc gcggcagggg ttcgcaggca
     4381 ggccgcgggg tgggctccga ggcgggcgtt agtgtctgtc ctttcggaca tgttggttgg
     4441 cgcggccgtg ctcgtggggc ggcgagagga tgtccttcgg gacatgtcga tcgccgcggt
     4501 tggtggaggg cggcggagga tgtccttcgg gacaggggat gcggaggggc tcgcggccgg
     4561 gtgacggcgc ggtcaggggg ttggagccgg cgtggcgggc tccgcgacgc agggacctcc
     4621 ggggggttcc gagaactcga gttcggcgtc gccggcgagc tggtctttgg gacatgggat
     4681 cgcggaccag cgagctcgag catatgcggc gcacctagcg cccaacccat gaaagcggtc
     4741 cgagcagcct ggcgccgtgg ccgcggcgag cccggcgatg ggcttttcgg ggctgtttgg
     4801 gccggtttgg cggcgggggg cggcgagcga gggtggcgtg gaggtgcgtg ccgccgcgct
     4861 cgtgccatgg agaagccatg acgacagggc agagcagttt ctccaccgac atcgcgacca
     4921 tccgcaagcg agcgcgcgag cacctcgagc aaggcgcgct cacgccgaac tacggcgccg
     4981 acgtcgagac ggcgatccgc gtgctcaacg aggcgctggc gaccgagatc gtgtgtgtgc
     5041 tccgctaccg cttccacgcg gtcaccgcga cggggatcgc cagcgagtcc gtgaaggcgg
     5101 agttcgagga gcacgcgcag gaggaagagg cgcacatgct gtggatcgcc gagcgcatca
     5161 accagctcgg cggcaagccc aacttcaacc ccgacggcct gtcgagccgc tcggcgtcgc
     5221 agtacgtcga gggcaagaac ctggtcgaca tgatcaagga agacctggtc gccgagcgga
     5281 tcgccatcga gacgtatcgc gagatgatcc gctacttcgc cgagcacgac ccgaccacgc
     5341 gcatgctcct cgaaaagatc ctcgcccagg aggaggagca cgccaacgac atgcacgacc
     5401 tgctggtcgc gcacgagggc aagccgatgc tcgaccacta gagggcggcg cgagcgggcg
     5461 gcgccgcgtg caggcggatg tcgttcggga catgttcgcc cgaggcccgg gcgaggagtc
     5521 gcgccgtcac gcgcagctcc cgacgacgcc gcgcaggtag ctgcgctggc ggcgatcgag
     5581 cgcggcggtg atccgcgtca ggggcactcc tcggcgcggt tggcgggcga cagtaggggg
     5641 tcctcgtcgt cctgctcgat ggaggtcgag ccgcatgacg gggccgatgg gactggcagc
     5701 ggccagggcg gctcgcgtcg ccggtcatgc cgtcaggcgt agctctcgac gacgccgcgc
     5761 aggtagctgc gcttgcggcg atcgagggcg gcggtgacca tcgtcagcgg gcactcctcg
     5821 gcgccgtcgg cgaggcggat gatgggcagg cggtagtaga cgttgtcctc gtcgtccagc
     5881 tcgatggccc aggcggcgtc gtcgaggttg agcagcatga cgaggccgat gtgacgggcc
     5941 gcggcgtcga ggatctcgcg ctcgccgatc ttcaagatct ggttcgggcg gcggtacctg
     6001 gccaggagga aggactccag ggtgtcgagg gactcgaggt cggtgccgag cggctcgccg
     6061 atcagggcgt agagctcgtc ccggacctcg acgtcgccgg ccagccagac ctggaacgcc
     6121 tctcgcgagt gcagcagcag cgcttcgtgc atgggcggag cttagtcgag gggggcgccg
     6181 attgtctcga cggcggcgcg gctcgcagga gctacgaacg gcgaggacag gtggcgacag
     6241 cggcccgtcg agcgggctcc gaagatggcc ttcgggacat gtcgggagag gcgacgggcc
     6301 tgggcgcggc gagggtcagg agagccgctc gtcgagccag gcgagcgcct cggactcggt
     6361 gccgcacagg cggagggtgt tggggcggcc gctgaggcgg agcatcaggt tgatggccgc
     6421 gcggacgagc gggctgctgg tgacggtgca ggtcgggccg gcctcgccca tggtctgaag
     6481 gtgcttgcgc gcctcggtgg tgtactcggt gccgcgcggg accaccgaca tcgagggttt
     6541 catgtagtag gggccgtcct tgccgaagcg ctggacgaac tgctcggcct cggtgaggcc
     6601 gaactcgccg gcgacggtca cgcgcacgta cgggcgaccc cggggcgtca ggagctcttc
     6661 gaaggcgatg gacatggtcg tggctccgca gcgcggctgg gtggatggga gggagcgacg
     6721 cgtcgccccc agtccgcaac tttaagaaag ggcgcggggg agggtcaatc gcgtcgccgg
     6781 cgggtgtttg ccgggcgagg tcggggcgca ggcgtcaacg tcgtactcgc gagtgccgcg
     6841 aaaccgcgtg tgtcggcgcg gcgtggcggt gagcgctggc gaacgcgggg gcgctgcggg
     6901 atctcgcgcg ggtgcttcca gcgcgaccag agtgagcgcg gagcagtggg ccgccgagcg
     6961 tggagcggtg catccacgtg ggggctcaag tgcggacggg cgaacgacgg cgagggcgag
     7021 tctggtcgtt gccgcgtggc agcggggatc gagcgcgggc gggcgagacg agagtgcgcc
     7081 tggctggtcg atgagacatg tcgacacgga catgtggaat ggagcatgac cgttcgggca
     7141 tgtccgagag gtcacccgcc ccagaaggcg acgacgtcgg cgatggtgtc gcgcgggcgg
     7201 aggacggtga ccgcgtcgcc gtcgaggccg agggcggcgg ggatcgcccg gctgcagtag
     7261 cgcgaccaca tcgacagggt gtaggcgccg gtgtcgcgga tcaggacgtg gtcgccgggg
     7321 gcgagggccg gcaacgggag gtcgcgggcg agcacgtccc cgccgaagca cagcgggccg
     7381 gcgagggtgg tggcgacggg gtcgccggcg aggggcaggc cgtcgcggcc tatggcgagg
     7441 aagtcgtggt gccactcgtg ggggcggtag acgcggcgca cgaacaggtc ggcgccgacg
     7501 tgaaggccgg cgacggggcc gggcttgacg acctcgacgc gcgagacgac gaagccgcag
     7561 tcggcgagga tcgagcggcc gaactcggtg acgagctgga cgtcgccgcg gaacaggtcg
     7621 gggacggcgg cgcgcagggc ggcggcgtag gccgtgggag tgaggcgtgg ggcgtcgtcg
     7681 cggtactggg caggcaggcc gccgccgagg tcgaacatgt cgagcgggac aggtcgcacg
     7741 gcgaccagct cgcgccgcag ctgccacacg cgggcgacgc cgtcgacgag ctcggggatc
     7801 gtgacgccct gcgagccgat gtggacgtgc aggccggtga ggaagcggtg gcgggcgaag
     7861 gcctcgacga tggcagagtg ctgcgacaga gggacgccga agcggctgcc gcggtggccc
     7921 acgctggtga gggcgatggc ggcctcggcg agctcggggt tgatccgcag gccgatccgg
     7981 ctggcgcagg ccggggtgtg gagggcggcg atccgctcga tctcggcgaa gttgtcggcg
     8041 ttgatccgca ggcccatgcg cagggcctcg gccagctcgg cctcggtctt gaccggggag
     8101 tcgaagacga tccggtcggg gctgcaacct gctcgaaggg ccaggtggac ctcctcgatg
     8161 gaggcggcct cgagaccggc gcccgcggcc accgcgacgc gcaggacgcc gaccagcggg
     8221 ttggccttga tcgccacggt gtgcaaggcg cggggtcccg cgaacgcagc ggcgacgtcg
     8281 gcgagcttgg cgcggaggcg gtcgaggtcg tggacgagca ccgccggctc gtcggcgtga
     8341 ccggccgcgc gtacgcggcg gaaggcctct gcgagctgtt cgggcgcagg acgggcgtcg
     8401 acggcgatcg gcacgatcga gagcgtcgcc catgtcgcgc gcgcgcgcca gagcgccaca
     8461 cccctcgcat ggcggcgcgc tgcctgcggc gacggccgct gcgcgggtcg gccacggcgg
     8521 cgtgaggcgt tgcgaggagc cgaggtctgg agcgcgtgcg gccggcgccg cgtcagttgc
     8581 gttcgctggt gaggatcgcc ttggcggcgt cgtggccgct ctggacggcg gactcgatgg
     8641 tggcgggcag gccggtgcgg acccagtcgc cggccatgta gaggccgcgc acggggccgg
     8701 tgacctcggg gcggcagtgg taggtgccgg cggcgtggga gatggtggcg cgcttctcct
     8761 tgatgacctt gaagcgcttg atcttggggc cctgggggcc ggcggccggg aagtagcgct
     8821 ggagctcgga ctgcagcagc gcctgcaggg tctccggcgg gtcgtcgacg caggcccggg
     8881 cggcgctgat cgtgcagttc atcatgacct cgctgccgac ctcgccctcg atctgcgagc
     8941 ggttgaacat ccagtgcagc gggccggcga ccaggccgac gaacgggtcc tcaaacgggg
     9001 cgcggtcgac cgagaaccac aggttgacga tcggcgacgg gcgcaggcgg gcgatgtcct
     9061 gatagacagg gtggttgggc aatgtccccg ggagcatgtc cagaaaggct tgcgggggga
     9121 cggtcgagac gacgacgtcg gcggcgaggg tgtcgcccga cttgagggtg acgccggtga
     9181 cgcgcgagtt cacgacctcg agcgcgcgca ccggctcgcc gaggcgcagc tcgcagccgc
     9241 gggcgcgcag gtaggccagc gactgctcga cgtagaggcg cgacagcggg accttgggca
     9301 cgccgaggcg cgaggcgtcg cggctggtga ggaaggcgcg gtcgagcacg gcggtgaaca
     9361 tcgccgccga cgagaccagg gggtcgtcgt tgagggtgcc ccagatcagc gggtcccaga
     9421 aggcgttgcg cagggtcgcg gtctggccca ggcggcgcag ccagctgtcg caggtctcgt
     9481 tgtcgtcggg gcgctggacc tcgccgcgca gcatgaggcc ggcgcgcagg gccgcggcct
     9541 tgtcgagcac gccgagcccg cgcatggtca aaaggccggt ggcgaggtgc agcggcgccg
     9601 gcagggccgg gcactgcagg tgcagccgct tgccgcccgg cttcaccatc gtcacctcga
     9661 ggttcttctg gaagtagacg ccgtcggtgc tgtcgatcgc gcgcaggaac gccagggtct
     9721 cgcggtagca gcccatcatc aggtgctggc cgttgtcgac ctcgcggtcc agggtggcgt
     9781 cgtggaacga gcgggcccgg cctccgccgg cgcgggtggc ctcgatcagg gtgacgaccc
     9841 ggccggcctc ggccaggcgc actgcggcgg acaggccggc gaggccgccg ccgatcacga
     9901 tgacgctgcg ggtgctttcg gacatgacgg aaaggacatt ctcgagagga cagggccaaa
     9961 gcgacaggtc cggggggaca tggcccccgg gacaggacgc tcaggacagg acgctggccc
    10021 cggcgcgggc cagcgcgagg aaggcgacgc ggagcttgtc gcggcggcgc agcgaggcgc
    10081 ggcgggtgaa cacgttgtag ttgcgggccc ggatctcctg caagatctcg tagtaggtgc
    10141 ggcccatgat ctcggccggc aggaggcggc gctgctggat ctccggcagc agcgcccagg
    10201 cggcgtggta ctcgcgctcc gccgcggcgg cgaagtcggc cgcggcgccg acgaaccggc
    10261 cgtcgtagcg gtagttgaag acgtcgtcgg gcgtgaggcc gtggcgcgcc agcagctcga
    10321 gcgggaggta gatccggccg cgcgcggcgt cctcggcgac gtcgcggagg atgttggtgt
    10381 actgcagcgc gaggccgagg tgctcggcgt agcggcgggc cggctcgcgc tggtccttga
    10441 agagcgccag gcacaggaag ccgacgcacg aggcgacgcg gtagcagtag agccgcagct
    10501 gctccatgtc gtcgtaggtg ttgcggtcga ggtccatggc gacgccggcg atgatctcgt
    10561 cgaaggcgtc gcgcgggtag tgaaagtgct tgttgctctc ggccagctgg cgcccgagct
    10621 cggtgtgcgg cgggtcgtcg tcgacgtagg cgtcgccgta gatccgcgcg acctcggcgc
    10681 tccagccggc cagggcgcgg cgggccgcct cctcgccggc gggcccgggc tcgcgctcgt
    10741 cgacgatgtc gtcgacgacg cggcagaact cgtagacctg ctgcaggccc tcgcgctgct
    10801 cggggcccag gaacaagaac gcgaacttga agttcgagtt ggagcgctgc accagccgcc
    10861 gccacagggc gacggcgccg ctcgggatcg tgcgcgcgag ttccatgagc tgggccatcg
    10921 tgcagctaca cctcgccgcg gaggaagcgg cggccgaacg agaagatcga gcgcgcggcg
    10981 atgccgagca tgtcttgctt ctcgagggtg gggcggaagc cgagcacctc gtagtcgagg
    11041 tcctcgatgc gctggaggat ggccatgccg ccgcgccagg tcgcctcgag ctccatcgac
    11101 aggccgggct cgacgcggcg gaccagcggg tagccgcgga ggaacatgct gcggcagcgc
    11161 gagaccgaga acgccatcag ctccttgaag gcgcgggtgt ggcgggcggc gagcaggtct
    11221 tcgcgggtga cgttgaagtg gacgaggtcc tcctcgggca ggtagcagcg gccgcgcggg
    11281 gtgtcgacgc tcagatcctg gaggaagttg gcgatctgca gggcggcgca gatctcgtcg
    11341 ctgaagcggt gcagctcggg ctcgtggtgg ccgtggacgt agagcaccag ctggccgacc
    11401 gggtgggccg agtgcttgca gtagtggcgc agctcggcaa acatgccgta gcgcttctgc
    11461 gtgaggtcca tgcggaaggc ggtcagcagc gccttgaacg ggccgatcgg gatgttgtgg
    11521 cggcgcaccg tgtcgcgcag ggccaggaac accgggtgct ggatctcctt gtggtaggcg
    11581 gcgaccagca gctgctccca gcgatcgagg gcgtcgacgc ggcggctctc gaaccgcggc
    11641 tcgtcggcga agtcgtcggc ggtgcgggcg aaggcgtaga tcgccatgat gttcggccgc
    11701 aggtgcgccg gcaggaagcg cgaggcgacc gggaagttct cgtagtgcgt ggtggccatg
    11761 cgctcgcagt agcgataggc cgtctcgagg gtccacgggc cgggaggggc cccgtcgggc
    11821 gagctgacgc gctgaccctc gaggtcgccc tcgggaggcg gagggacgca gaagaggcgg
    11881 ggttccgtgg cgctgaccat gacggggttc tccgaggagt gacaggcgag gcgaggtcgt
    11941 gcggggcttc ggcgatcgtg ctggtgcagg acgcggtgtg tcgttgcgag ccgccgcgag
    12001 gttctcaggg tgagcggaag tctaacggct ttcggatcgg agctcgtgca gcaggaggac
    12061 cgcgcgatcg tgcttgatct cggccgactc cacgagtcgg tggacgagga ggtcgacctc
    12121 cgcgccctgg gccccggccc cgaccgcgac ggagcgggcg tggagcgaca tgtggccgcg
    12181 ctggatgcct tcggtggcga gggcgcgcaa ggccgcgaga ttgctggcga gtccgactgc
    12241 ggccatgact tgacccagct cggcgcccga ggtcgcgccg aggatctcga gcgcgagcct
    12301 ggccgcgggg tgcaccttgg tggcgccccc gaccacgccc acagccgcag gcaggctgat
    12361 cgcgccgcac aaccagcctt cggggtcgag ccgccaggtg gcgagcggac ggtaggcgcc
    12421 ggtgagaccc gcgtacgcgt gggcgccggc ctcgatcgcg cgccagtcct ggccggtggc
    12481 gagggcgacc gcgtcgacgc cgttcatgac gcccttgttg tgggtggcgg cgcggtaggg
    12541 gtcgagctcg gcgaagcgcg aggcggaggc gatgccggcc gccgcggcgg cgcccgagaa
    12601 gccgcgcccg gccagcgcgc caggaggcac gcggcaggtg acgtgggccc gccggcgatc
    12661 ggcgaggttg ctgaggatcc gcagaccggc tgtccatccg gtcatgtccg aaaggcgggg
    12721 cgcgaggacc tcggcgatcg tgttgagcag gttggcgccc atggcgtcct ggcagtcgac
    12781 gacgacgtcg acgacgagca tgtcgggcgc gaggacgcgg accagcaggt cgcgcgcgcc
    12841 gccgccgcga gcgacgaggc gcgggtgggc cgagtcggcg agggcgagca ggtccccccg
    12901 cgcggcgtgg atggccgcga cggccggctg cggcgcgggc tcgccggccc tgggcgcggt
    12961 cagctggacc tgggcgatca tccacggcgg gtcgctgcgg gcgaagaagc cgccgccggc
    13021 gcggatcatc ttggcggcgt tggaggccgc ggcgaccacc gaggcctcct cgacggccat
    13081 cggcaccagg aagtcgcggc cgttgatgcg gaagttggtg gcgaccgcga gcgggagctc
    13141 gagcgtgccg atgacgttct cgatcaggtt gtcggcgctg ccgaggtcga ggctgccggg
    13201 gtcgagggcg gcgaagcggt cgcgcgggat gtgggtggcg gccgcgactg cgtcgcgccg
    13261 gccgtcgacg ccgaggcgga agaagccgga catgcgcgag gacagcggcg gccgctcgtc
    13321 gcggcgcagg ccgggggcgg ccacagggag gcggccgatc gcggccaggc cgtgctcgcg
    13381 atgcagtcgc tcggcgagca ggtcgaggtc ggcctgacgg gcggcgaaca cgaccacgag
    13441 gtcgcccccg ccggcgccgc tcggcttggc ggcgaggccc atgcgcgcgg cctgatcgac
    13501 gatcgtggcg atcgtcgggg tgacgatcgg ggcgtcgctc aggcgctgca gggcgcgcag
    13561 gccgtcgttg tggagggcga ccgcgtcgcg gatggcggtg aggccgacgt cggcgtcggt
    13621 gctgtcgtag ccgccgcgga acagctcggc ggcgcggcgc agctgggcgg tggcggcggc
    13681 gtgggcggcg gggtcgcgct cgccggcggc gcggacctgc tggacgaacg aggcggtgtc
    13741 ggcgggcgcg ccggcgtcga agaagccgat gtgcagccag gccgggtggg cgaccgggac
    13801 cggggcctcg ccgcgggtga aggcgatcgt gccgccgagg accgcgcagg cgacgtcggc
    13861 cccgctgccg ccgccctgga cctgggcgtg ggcggcctgg gccaggcgca gggcgatggc
    13921 gcggacggcc gggtcctcga ggtcgtggcc ggcctcggcg aggtggaagc cgaccaccgc
    13981 ggcgacggcc gcggccgagc tgccgagccc gagcttgcgc gcgccggcgg cgaacgagcc
    14041 ggtgtcgacg ctggtcaagg ggccaggtgc tttggttcct gtgctttcgg acaggaactg
    14101 gcggacatgc gcgtaggcgg cctcggtcag cgccgaggcc ggcgggcggt cggggtcgtc
    14161 gcagtcggcg gcgacggccc ggcggccgac ggcggtgacg agggcggtgg cgccggcgag
    14221 caccgcgtac tcgccgatca agaacgcctt gcccggggcg gagactgcca ggcgggtcac
    14281 gcgaacacct cgacggtggg gtcggggccg gggccgacga cgtcgaccgc gtggaccccg
    14341 gcgacgccgc gcaggcggac ggccagctcg tcggcctggt ccgcggcgca caggaccttg
    14401 acgtgcggtc cggcgtcgct ggtgacgtag ccgcgcaggc cctcggcgcg caggcgccac
    14461 accgcgtgga tgacgtcgag ggtggcgccg cgccagtaca cgatcggcgg gcggctggcc
    14521 atcatgcagg cgtgcatctt gaagcaggag tgttcgagga tgtccccgag gacagccagg
    14581 tcgcgggccg ccagcgcggc ctcggcggcg gcgaggtcgg cctcggaggt gtcgacccac
    14641 gggccgtagt agggcgaggt gtcgcggctg cgctgcatgc cggcggtcga gccgatcgcc
    14701 ttggggccgc gctcggtgtg gacgatgagc aggcggacgt cccagtgcga ctgcggctgc
    14761 agcgggtagg cccggcagtc gctgccgtcc gggaggacgc cgcgctcgag gcggacgaag
    14821 ccgccccaca gcgagcgcgc ggccgagccg gagccgcggc gcgcgagggc cgagagggcg
    14881 ggccggccgg gctcgtagtc gaaggcggcg gcggcggcga gggtcagcgc ggcgaagccc
    14941 gaggccgagc tggcgaggcc ggcggcggtg ggcaggtagt tgtgcgaggc gacggcgcag
    15001 gccgggcgcg gaccggcgtg gccggcggcc tgccacacgc ggtcgagctg gcgcatcacc
    15061 ttggccgcga cctcgcccga ggctggctct tggttcaggt ggaaagagtc ctggtccccg
    15121 ggacagacgg tcgtctcgct gcgcagacga tcgagggtca gcgacagcga gccgacggcc
    15181 ggcaggttga ggtcgggcgg cgacgagtcg cgcttccccc agtacttgac gagggcgatg
    15241 ttggtgtggg cgacggcgcg ggcgctcttc atgacgcggc gacctcgacg aacagcggac
    15301 ggagggaggg gaaggcggcg gtgagtctgt cgggggcgtc gccggcgagg gccagcaggc
    15361 agccgccgca gccggccccg gtgagcttgg ccccgcgcgc gccggcggcc cgcgcgtcgg
    15421 cggccatgcg atcgagcgcg ggcgaggaga cgtcgagcgc gccgagcagg ccgtgggcga
    15481 cgtcgaagag gacgccgaga gtgtcgaggt cgccgtgctc gatggcgtgg atgcccgact
    15541 cgacggcctg accgatggcg atcaggaccg ggcggacgac gctcggcagg tgctcgaggc
    15601 ggctgcggca gcgcgcgacc tgatcggcgg tgctgcgcgg gatgccgctg gggatgatgc
    15661 agagcggcag cggggcgccg gggttgatcg agcgcggcgg ctcgccgcgg acgtagcgga
    15721 ggacgccgcc ctgggcggcg acgcggctgt cgaggcccga gggctcgccg tggaacacgc
    15781 gctcgccggc cagcgaggcg gcgacgacgt cgtcgacgcc ggcgtctggc ccgaagacca
    15841 ggcgggcgag agccacggtg agcgccgccg aggagccgag gccggcgcgc gagggcaagg
    15901 cgctggtgcc gtggatcgcc cagccggtga cggggccgtc gcagtgggcg aggacctcga
    15961 ggcaggcgcg cgcgaccgga tgatcgctgc cggcgtgcag ctcgaggtcg aggtcccagg
    16021 cggggacggt gagggtgatc ggcaggcgcg ggtcgggccg cgggcgcgcc tcgaggacga
    16081 tgccctgcgg caggccggcg gcgacggccg ggtagccgta gacgacggcg tgctcgccga
    16141 ggacgatgac cttgccgtgc gcctcggcgc gcgggtgcag ggggatgctc atcgccgcgg
    16201 ctccgggacc cagcgggcga gggtggggcc gagcacccgc ggggcgcgct gcaggtcggc
    16261 gacggtgcgc gagccggtga ggagcatgat gctgcggacg gtgaggacga cgcggcggag
    16321 gaaggcgacc acgccgtcgt agccgccggc gcggtgggcc ttgagcaccg gcgccgcgag
    16381 accgccggcg gtggcgccga gggcgaccgc gcgggcgacg tcgctgccgg tgcgcaggcc
    16441 gccggtggcg acgatgccgc ggaagccgag gccctggacc tgcaggacgc tggcggcggt
    16501 ggggatgccc cagtcccaca gctcgtcggc gagggcccgc tcgtcggggt cgacggcgcg
    16561 gtgggcctcg acggcgaccc agctggtgcc gcccgagccg ctgacgtcga ggtgctcgac
    16621 gccgacgctg cggacccgct cggcgacgcc gcgcgacagg ccgcagccgg tctccttggc
    16681 gacgaccggg atgtgcagct cctcgacgag gcggcgcagg gtgtcgaggc cgcgcgagaa
    16741 gtcgcgatct ccgcccggct ggacgatttc catggccggg ttgaggtgga tgcagagggc
    16801 gtcggcgccg gtgtcgcggc acagggtcgc gatctcggcg gtggtcatgg cgcgggcctg
    16861 gacgatgccg aggttgccga gcaagaggac gttcggggcc tgctcgcgga ccttgaaggt
    16921 gtgggcggtg tgcgggcgga cgaacatggc ccgctggctg ccgaggccga agccgaggcc
    16981 gagctggtcg gcggcgcgcg cgaggtcctg gttgatgacc gcggcctcct cggtgccgcc
    17041 ggtcatcgcg gcgatgacga cgggcgcgcg caggcgcttg ccgagcagct cgacgctcga
    17101 gtcgatgtcg tcgaggtgca tctcgggcag ggcatcgtgc accagctcca cctgctccag
    17161 gaggctggtc ttgtcccgga aaccgacgtt gtcgccggcg cacagggcga ggtgatcctt
    17221 cttgcgctgc gagatgtcga ggcgatcggc catgagcccc ggcaatgtag ctgctagccc
    17281 caggtggccg cccgctccgc cacgcgccgg cccgtgcgga aactcgttcc cgcgcccgga
    17341 tgtcgcaaaa gacgggcgcc ggcgccgccc ggacccgtga tccgcagcac agggccgagc
    17401 gccttcgggt gatcccgcag ccggtccgca cgcgcgcgca cggccgctcg aaccgcgttc
    17461 tcaggacatg tcggatcggg catgaccgat cggccaggtc attccaggcc gcgtgggagg
    17521 gccctccgga tggccgcgag cgaggtgccg tcctccagaa agagggtctc gcggacctgc
    17581 ggcaagaaga aggcggagag gtcgcgggtg ttgcgcggga ggacagcccg cacgggtcgc
    17641 cgtcgtcggc gaagagccgg ccgtcgacct acccgtcggc tccgccgcag cagaggccgt
    17701 ggtccgcgag ccagcgcgga ggttcagcgc ggcgcgctcg atgccgagct gcagctcggc
    17761 ccgccgtcgc cggtgagggg ccgacgctgc gatcgatctg tccgtaggac caggtgccgg
    17821 gcgagacggc ggcgtcgcgg acgagatgtc cgaagggtca tgtcgagacc gatcgccaca
    17881 gacgcccgtc gcggcgagcg cgacggagcg aaggcgcgag gtgtccgaag ggacatgtcg
    17941 agtcgcaggg cccgaggtcg cgaactcgag cccggatcga tggatccggg ggtcgggtct
    18001 ccgcggcccc aggccgccgg gagcgcttgt cgggccgatg ttgctctgat agaggtcgac
    18061 gcatggtctt cgctcgtcgt gcttgttcgt gcgcgctgtt gtccatgctc tggctcgcgg
    18121 cctgcagctc cgcgaaggag cccggcgaaa ctgccaccga gggatcgggc aatccgagcg
    18181 gcgatccgac cggcggcggt cagggccacg ccgcatgcga gaagtacctg gcgtgcgtcg
    18241 cggtcgtctt gccgtccgag ctacccgacg ccgaggcggg cttcggccag gcggggacgt
    18301 gctggcagag cacgcccgag atcgcgcagg gctgcgtcga cgcctgcgag tccggcctcg
    18361 tggccttcgc catgatgtac ccgaacgagc cggcgtgcgg cggcagcggg atgggcacga
    18421 ccggcacgac ggagagcccc acgacgacgg aggggacgac gacggagggg acgacgacgg
    18481 aggggacgac gacggagggg acgacgacgg aggggacgac gacggagggg acgacgacgg
    18541 aggggacgac gacggagggg acgacgacgg ccaccaccga cacctcggcc gggccgatga
    18601 ccacggacat cgggccgtgc gaggacctgc cccttcagcc cgacggcgcg acctgcacgc
    18661 agccgagcgg gtgcggctgc agctccggca agtgcttcgt ctatccggtc ttcggcggct
    18721 attgtggcga gtgcctggtc gacgccgact gcgacggcgg aggctgcacg gggcccaacc
    18781 cgttcaccgg cccgggggcc gtgtgcaacg acggcggccc cggcgacggc tgccagtccg
    18841 acgcggtctg ctccgacccg aacaacggcg tctgcgcggc ggtcatcgag gtccccggca
    18901 tcatcacggt ctcgacctgc ggcgagtgcc agaccgacgc ggactgcagc gctccgacgc
    18961 ccgtgtgcgc gccgaagtac gacgtcgccg atttcagcgg gcggttcgac tgcgtggcca
    19021 agggctcggt ggcgaacaac ggcggctgca acagcgacgc ggcctgcgcg tccggccact
    19081 gcggcgcggc gagtctcatg ggcctggtcc agttcggcgt ctgcggcgag tgcctcaccg
    19141 acgccgactg cagccccgga gagcagtgcg tcgaggggga ggccgacctc ggcggtggca
    19201 agctgaccgg cgcgacttgc gagtgagcgc gtcggcgccg gcgtgagcag ggtcgatggg
    19261 acatggtggt gaggacatgt ccatgcgaac atgtcttttt cgacatgcca ctcgtcggtc
    19321 gtgagggctc gatctcaggg gagagctgtc ccgaggggca ggttacggtc cggaggcctc
    19381 ggcgcggggg accgcgggcg caggtcggct gcgaggtcgc ggcggacgac gaggctgccc
    19441 ggcggacgca ggtcggctgc gggcgacgag gccgcccggc ggccgtgtgc gccggctgcc
    19501 catgaaggcg acgaggctgc tcggcgggcc gtgtacgtcg tgctcatgac ggcgccgggg
    19561 cgcatccgcg gccgcgacag cgcgccggtc ccgttcctgg cgcgcgcgcc aggtcgagcg
    19621 gtccggctgg cgtgcgcggc gggccagcgc cgcgacctcg ccgcagccgc ggccgtgggg
    19681 ccgggttcag ggagcggggc ccgcggccgc tccgccgcgg ttgcgcgcgg ccagggagtc
    19741 gcgctacgga tcgggcgcga tgcacctgac gcaaaggctc cccaacggcg tgaccgtgta
    19801 caagtggccg cacaacgtcg agccgaccgc cgagtcggtg gcggccgaga tggcccgctt
    19861 cggcttccgc agctacgacc ttcagaccgt gccgccgtgg ttcttccgca gccggcacgc
    19921 gcacgacgag gaggagatcc gcggggcggt cagcggggtg acgacgttcc acttcgacga
    19981 ggggccggtg acgctcgagg ccggcgacat cctgatcatc ccgtcggggg tgcagcacga
    20041 ggtccgtagc cacaacgggc gcacgttctc ggcctacaag ggctcgcgca gcggcgagcg
    20101 ccacgtcacc gagcacggcg acggccgcgg cagcgtcgag gacctggccg gcggaggcaa
    20161 gtcgtgagcc acctgatcgc cctcgacctc gacggcacgc tcgaggacag ccgcgacgac
    20221 atggtggcgg cggtgctgcg ggtgcgcgcg agcttcggcc tgtccgaaca gccaggtgac
    20281 acgtaccgcc cgtacgtgaa cgccggcatg gaccacctgt accgcagctg cttcaaggag
    20341 tacgtcggcg cgggcgggac ggtcgacgac gtccgcgcgg cctacgaggc cgactacctg
    20401 gcccacatcg ccgacacgac ccggctctac ccggggatgg gcgacgcgct ggtcgagctg
    20461 gcggcgctcg gcagcctggc ctgcgtgacc aacaagccgc agcgcctcag cgcggcgctg
    20521 ctcgaggcgc tcggggtcgg gcgcctgttc tccgcggtga tcggcggcga cacctgtccc
    20581 gagagcaagc cgagcccgat ggtcctggcc gaggccagcc gccgcgtcgg ccgcacgggc
    20641 gctgccctga tgatcggtga ctcggccgcg gacgtgaagt gcgggcgctc gttcggcgcg
    20701 acgacgatct ggtgcgcgtg gggctacgcg gccgaccccg gcgccgagac tcccgaccac
    20761 cgcgccgcga cgccgctcga cctgcctcgg ctggtgcgct cgctggtcgc gtgaggcgcg
    20821 agtcgtgacg acggcgaggc tgtccgaagg gacatgcctc gtccgggcat gtgcctcgtg
    20881 attcgtcgcg cttgctggcc gtgcgggggc cttcgtggtg cgtcatccgg ggatctccgc
    20941 ttctcgtcgg tgcccgatcc atgatgtctt ggccctggca tggaaccccg cctcaagtcc
    21001 cccccgagca agctggcgaa gctgaagccg gcgatcgccg ccctccttcc ggggggcctg
    21061 cccgccgacg tcgcccgctt ctacgccaag agcgacggcc tgaagttctc cttgcagggc
    21121 gaagaggccg tcctcgtcgg cctcgccgag atgttcggcg ggctcaagaa gggggcgttt
    21181 cgcgggcacg tcgtcgtgaa gaaggcggac ctggacgagc tcgagtggtc ggatctcccg
    21241 ttttacgagc gtttcttcaa tgagtatgcg gacgtcttcg acaagaagtc gctcgaccgg
    21301 ctcaacctcc gcatgcggct caagctgctc gtcagcgtcg cgggcgagtc gaccgagctc
    21361 ggcatcgact acttcgacgc gaagcccacg atctacttcg tgcaccgcgc cgacgctgcg
    21421 tacccgctga aggacctcgg gttcgacgac ttcgtcgaat ggttcgcgaa gttcggcacg
    21481 cgccgctggt acttcgcctt cctcgacaag aaagccgagg cgagtctcaa catcgatctc
    21541 cgcgcggagc tcgagcgctc gctcgaggat ttcccgccgg aagcatgggc gccgctcctc
    21601 gcgcgcctcc cgaagaagaa ggagcccggt cccgtgcgcg cgcaggtgct cgccgctgcg
    21661 agtgaccgac cggtcgtcct cacgtccttc ccgccgctga agcagccgcc cgaggtcctc
    21721 gacgaggagc acccgcgcgg cgtggcgttc agcgccgacg gccagcacct cgtggtatgg
    21781 ggcgccaacc acgaggtcgt cgtccacgac gtgggccgcc gcgagcggct ctggaagcag
    21841 aagcacgcgg aggcgatgga cctgtccgcg gacggccaga ccgtcgcggt gctcgagcac
//
