LOCUS       NZ_CP114040            20924 bp    DNA     circular CON 26-AUG-2024
DEFINITION  Nannocystis poenicansa strain FL3 chromosome, complete genome.
ACCESSION   NZ_CP114040
VERSION     NZ_CP114040.1
KEYWORDS    RefSeq.
SOURCE      Nannocystis poenicansa
  ORGANISM  Nannocystis poenicansa
            Bacteria; Myxococcota; Polyangia; Nannocystales; Nannocystaceae;
            Nannocystis.
REFERENCE   1  (bases 1 to 13228663)
  AUTHORS   Ahearne,A., Stevens,C. and Dowd,S.
  TITLE     Minimal conservation of predation-associated metabolite biosynthetic
            gene clusters underscores biosynthetic potential of Myxococcota
            including descriptions for ten novel species: Archangium lansinium
            sp. nov., Myxococcus landrumus sp. nov., Nannocystis bai
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 13228663)
  AUTHORS   Ahearne,A., Stevens,C. and Dowd,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-NOV-2022) Biomolecular Sciences, University of
            Mississippi, Faser Hall 407, Oxford, MS 38655, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2021
            Assembly Method                   :: IPA v. 10.1.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 250x
            Sequencing Technology             :: PacBio Sequel IIe
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_026965555.1-RS_2024_08_26
            Annotation Date                   :: 08/26/2024 12:45:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,229
            CDSs (total)                      :: 10,129
            Genes (coding)                    :: 10,068
            CDSs (with protein)               :: 10,068
            Genes (RNA)                       :: 100
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 9 of 61
            Pseudo Genes (incomplete)         :: 52 of 61
            Pseudo Genes (internal stop)      :: 2 of 61
            Pseudo Genes (multiple problems)  :: 2 of 61
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:28:22
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2960174
            Orig. end                         :: 2981098
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP114040.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20924
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="8"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20924
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20924
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10924](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10924)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(859..875)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 18.54"
                     /tool="antismash"
     misc_feature    859..875
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 18.03"
                     /tool="antismash"
     misc_feature    862..871
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 17.48"
                     /tool="antismash"
     gene            complement(1002..2156)
                     /locus_tag="O0S08_RS11215"
                     /old_locus_tag="O0S08_11215"
     CDS             complement(1002..2156)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS11215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_11215"
                     /product="hypothetical protein"
                     /protein_id="WP_269039074.1"
                     /transl_table=11
                     /translation="MAPTRTLADSLWPRSAGDAGNRRVFAADGPTQPRLSPPLELPRSP
                     SDLHVVSGGVLGDDGDLRLVHGDFLSRVTLAGAVRWSLSLRAIELELTPPPEPDEDDDP
                     PPGEDAEDEDEERVSHSLPTALRGGRTLITVRHAALIVDPDGRVEDRWLSWEHLCCGPD
                     DSGISPNVTHAGAPIITTPGGEWIVWEEPTARVLSAGAYDILPPALFADGSLALACYAG
                     DGLCRVRPSGERLWRAGPRDADLLPTVNRAQVCAVGSLNDECSLLLSPEGRPKGEHPVP
                     AVFAEYHDMGWIAVGERQVARLDPRGASMWTADLAHGLRWGVYGAIVDRQGRVYVQDDG
                     ALLGLDPRGRRLFELRLGDVAGAVFPVADGVFGVVVDGELRFIR"
     gene            2290..3123
                     /locus_tag="O0S08_RS11220"
                     /old_locus_tag="O0S08_11220"
     CDS             2290..3123
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (77-187). E-value:
                     9.5e-11. Score: 33.7. Matches aSDomain:
                     nrpspksdomains_O0S08_RS11220_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012770.5"
                     /locus_tag="O0S08_RS11220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_11220"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_269039075.1"
                     /sec_met_domain="PF00561 (E-value: 4.4e-06, bitscore: 25.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3.5e-07, bitscore:
                     30.3, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVPVPGVLAVLLVTGVLVYSASCTLQERVIFPREYANQRALASPP
                     AGVTPLWSPAADGTRVEAWFVPGRGASAERPGPAVMFFHGNGELIDHQLALAASYAARG
                     VSVLLPEYRGYGRSQGKPSQAAIVGDMLRFHDELAARPEVDRARVVFHGRSLGGGVASA
                     LAAVRPPAALILESTFTSLAALARKHGLPEALCRHPFRTDRVLPALQRPVLILHGSEDE
                     MIPVAHGRSLHTSAPGSTYVELPGGHNDFPRDRPAYERALDAFLRASGVLLEDRQ"
     aSDomain        2521..2850
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_O0S08_RS11220_Abhydrolase_1.1"
                     /evalue="9.50E-11"
                     /label="O0S08_RS11220_Abhydrolase_1.1"
                     /locus_tag="O0S08_RS11220"
                     /protein_end="187"
                     /protein_start="77"
                     /score="33.7"
                     /tool="antismash"
                     /translation="PAVMFFHGNGELIDHQLALAASYAARGVSVLLPEYRGYGRSQGKP
                     SQAAIVGDMLRFHDELAARPEVDRARVVFHGRSLGGGVASALAAVRPPAALILESTFTS
                     LAALAR"
     gene            3191..3652
                     /locus_tag="O0S08_RS11225"
                     /old_locus_tag="O0S08_11225"
     CDS             3191..3652
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS11225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_11225"
                     /product="hypothetical protein"
                     /protein_id="WP_269039076.1"
                     /transl_table=11
                     /translation="MRLRILEPCRENWDTMEPTEVGRRCEACSREVHDLTGLTARQAKR
                     LLTRAGPRPCVRVRADEDGLAVFRREPPRLAPAAAAMALAACAPHTPEAQRLAPAVEVE
                     PAAPPRPSPVIPEAARRPDATAEPGPPKPVKAPAKKPERERVLMGDPWD"
     gene            3975..5717
                     /locus_tag="O0S08_RS11230"
                     /old_locus_tag="O0S08_11230"
     CDS             3975..5717
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS11230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_11230"
                     /product="hypothetical protein"
                     /protein_id="WP_269039077.1"
                     /transl_table=11
                     /translation="MRRPCCALAVLLLLAVGCSRSGLQDASDLTADQLEAAGQSRCSVV
                     KDPDKPLIVEWSGMDAAELEARLLRGVVAVRYEDCEMEVLRGCTAPGQYSYAQTTTGSE
                     SIHIGSLDELLINIPLGLAQLGGRVERGEALELDMVVVGRYEAPRPAYTAAELSGGPEC
                     ARATHVVTGVSLGAFRLSSVEDSARSGSGAGLGGASEDTIEVLKESPPNMLEACAQVAA
                     ADDPRRNVCTAPIRLEVAPISAHAAALAESQQFLRPPDLDKREVQSMDLSGGLAAHQAY
                     DAAVKVQADRWATPERRTEAWCALAAIEQDNPYLAQARELCDRWRDHTTALRGSEARMI
                     RDYDELRVLLELRGVPVEVQERAAASFLVTHSGLSPEAYPRIRAVERAKRRLGRGDRTS
                     LPSFSAAAAGEPPAVDSQVRTSLVDRRSYRKALSIGFQPRWIPQGYALGGTVLGRVNYV
                     HEVGFEVAYAQYAGYGPRWRYILAMARYERVYRPHKVFRPYIGASFGALIPIGPMACSQ
                     VPQPCAAPAGVVTLNGGARVSLTPWLSLVAQGFAGAMTARPFFVGGVSGGIEFTIPTGR
                     DWPQ"
     gene            complement(5800..6324)
                     /locus_tag="O0S08_RS11235"
                     /old_locus_tag="O0S08_11235"
     CDS             complement(5800..6324)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS11235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_11235"
                     /product="hypothetical protein"
                     /protein_id="WP_269039078.1"
                     /transl_table=11
                     /translation="MRNKFFTIASALSLAGVIGTSVALAASVHFKGGKNAGPSFQDLGV
                     TLEARGTLAGLGNEDLLITLEATGDPTATCTNPAGSTQPPGQNPAEVTLTGVQSIPASA
                     IKNGNVSFDVTTAQPVSPIPGAPDCPNTKWTERILDISFTSAKITVEQPAGTIVLTANC
                     TFDDGIATCTD"
     misc_feature    6303..6320
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.51"
                     /tool="antismash"
     misc_feature    complement(6590..6605)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.86"
                     /tool="antismash"
     gene            complement(6700..9198)
                     /locus_tag="O0S08_RS11240"
                     /old_locus_tag="O0S08_11240"
     CDS             complement(6700..9198)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024907.5"
                     /locus_tag="O0S08_RS11240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_11240"
                     /product="VCBS repeat-containing protein"
                     /protein_id="WP_269039079.1"
                     /transl_table=11
                     /translation="MSRPSPAAFVAVTLASRVAAAAPWQLDPDVQLSDSGFVSQKVELV
                     DIDNDGFVDLVFANSAGDALGDAQDAQPNQLLRNDGAGFTELAGLFDEPDNAYAIKAGD
                     LDGDGDADLVVGVNFGGQSYALLNEGDGVFTRQDIPASAGKSIGDLELGDVDGDGDLDV
                     VAADWGASQPYGQQTDPGQPLRLWLGDGDGSFEDGDLNLPMGMETWASWSFDVELVDLD
                     NDYALDVLVSSRGPGFGFGLKNDGAGTFTHSTIPALAANVAKQVNAAFTPADLNGDGFL
                     DLVTLQDGAGQGGNCVDVMGVPTCARRNSILLNDGTGNYVTDNPGNFWATADNPAKLDF
                     DAATLDFDNDGRPDFVTTGLRLGANDRNSRLLLNKNGAAVEPAPVPLDAAFPIVPELAA
                     TFGLQFADFDHDRREDVAVVTRDAALPNFVLFGRDDPADGVAIDTTPPRIYDDGFADKL
                     GTLMYFGQQARFVARVDDSKTPVRWHDFQIDANLGDLDLIGDGATLTAHNRRLPYLEFA
                     LGLDDPNDLLALADGDPNKFIAPSIWFGEALWRVGFTVPYKGKEEDTLTWQYCAVDAAD
                     NKACVGPFSVTLLADPIDCGDGVVQPWETCDDDSPTCVACEQTCGDGILDEGETPQNCP
                     EDSGLCDDDGVCEPPENPQNCPGDCDYDGVCGDGTCQVPPENEDNCFEDCGPCDHDGAC
                     EPPENSAHCPDDCDYDGICGDGIRQSPPETPENCPQDGADPTGGEVCGDGVCDAGETIA
                     SCPHDCAVCGDEICTDPPENSEDCPSDCPAPPPDSGAAASGGQMDDDSACNCSTRPQPA
                     SAAWMLLGLVALARRRRIMT"
     gene            complement(10001..10924)
                     /locus_tag="O0S08_RS11245"
                     /old_locus_tag="O0S08_11245"
     CDS             complement(10001..10924)
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.4"
                     /locus_tag="O0S08_RS11245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_11245"
                     /product="terpene synthase family protein"
                     /protein_id="WP_269039080.1"
                     /sec_met_domain="T1TS (E-value: 1.3e-24, bitscore: 86.6,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGIDFDLGTVRGNRLTGTLVRMEVPGHGRAEPVGTPAEIDASED
                     ECVRWAERIGLIDAGGRYAAKFRLSQLAALSAHTLPDVRPARARWFIRLQAFIFTLDDA
                     LDNLGDIRVGADWLAHHQLAPVLAAFQRALAGQPADPELDRKAADFPRFSAFRAALVDI
                     RAEAVHEGGDLRWFVATMRDYFEAMTWEHSAHCDADYRGTLSTYLCNREQTISYLQSLE
                     SFLLLKRVDLSPAQRERHPVALLRTGACRHVILVNDIFSLAKELACAELDNVLLLADRR
                     DASLRARFHALLREVNALALALRPAS"
     gene            11225..11977
                     /locus_tag="O0S08_RS11250"
                     /old_locus_tag="O0S08_11250"
     CDS             11225..11977
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS11250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_11250"
                     /product="hypothetical protein"
                     /protein_id="WP_269039081.1"
                     /transl_table=11
                     /translation="MSSGPLEHAERRRAQIEEVRALRAGLAALIAGRTTREELSRWLRE
                     LWPPGSGQGGPFLWQPAACVYDSLLSLNRRWGEQELVREVELRAYLRWLGEGECCFTDD
                     GDSLFVLHRDIDELAAWAGVEAVRWWHSGLGWWTSLQFGSPASRRVFVVHSALERPDVV
                     GFHPQRGVAREEAIRELFEVLAIDDADVTRVDPQIDLERLPRWALIRQDDNGNRFEIAR
                     FRSYTKAYAQERTLTARGHKQLYWVEPA"
     gene            12047..13489
                     /locus_tag="O0S08_RS11255"
                     /old_locus_tag="O0S08_11255"
     CDS             12047..13489
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015244773.1"
                     /locus_tag="O0S08_RS11255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_11255"
                     /product="IS1380 family transposase"
                     /protein_id="WP_371879576.1"
                     /transl_table=11
                     /translation="MTTQGYGRNTTRCIRTEFDFQPAGRRRVEGAFDGGRVSSDGGLLL
                     LRELTESSGVFRDFASCFRDHRDPSRVEHTVEELLAQRVLGLLCGYEDLNDHDMLRDDA
                     LLALAVGKIDPTGEQRKRERDRGHALAGKSTLNRLELAKPTVAGDERYKKISYDDHGIQ
                     RLFVDTFLAAHDRPLAEIVLDLDATDDPVHGKQEGRFFHGFYDSYCYLPLYVFCGDFLL
                     GAALNTADKQPVSGAVEELERIVSQILARWPDVRVIVRGDSGFCRDEVMRWCEDNGLFF
                     VLGLQKNSRLIVEIEDEMKQARAISEQTGKEARVFKDFRYETNRTWSRERRVVGKAEYT
                     TDKENPRFVTTNLSHDEYDARSLYEDLYCARGDMENRIKEQQLGLFADRTSAHTLRANQ
                     LRLWLSSVAYMILNELRRLALAGTELAHAQVSTIRTRLLKIGAIVTASVRRIRVSLSSV
                     FPLQHVWWRVLENLHRHHVMRR"
     misc_feature    complement(12049..12064)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 22.24"
                     /tool="antismash"
     gene            14171..15565
                     /locus_tag="O0S08_RS11260"
                     /old_locus_tag="O0S08_11260"
     CDS             14171..15565
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS11260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_11260"
                     /product="hypothetical protein"
                     /protein_id="WP_269039082.1"
                     /transl_table=11
                     /translation="MRSLRALYCFAILLTACPDPTSATSASDSGDDSTTGATSEPTTGA
                     TSDPTTGSTGDDATGVDTEQSVAPVDLACDLMREACERQVACGHAIVNNNPGGVEACLA
                     EQRCETVGELLDLPNIELDPDAVEACIAALEAASCGELVAHGLEIDPSCSLYLAGTLGE
                     GEACHGGTVSDCAPGLSCVFEGGACPGTCAAPPAPCSEGSCGADAFCTVDGTCQPRAAL
                     GEACDETNIEFDNLSDRACAAGSHCQDSVCVADLGAGAQCGGLDVHACGDGACVCADLE
                     NCDETADFACGPVRGAGEPCSTAFDCAEGLYCDFYAGSRCAARGGRGEACNDSFGACLH
                     SLACADGTCADEQESVSDVSLLEEDESCIGGGSCPLGTACTCDDADCVDKHCLPAPGLG
                     ESCEAQDFDGYSCSEGLCDILASHICVLPGAAGEACPLDGLTFACASLFCIEGHCASVE
                     QTLCQE"
     misc_feature    14210..14212
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(15737..16360)
                     /locus_tag="O0S08_RS11265"
                     /old_locus_tag="O0S08_11265"
     CDS             complement(15737..16360)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002636395.1"
                     /locus_tag="O0S08_RS11265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_11265"
                     /product="hypothetical protein"
                     /protein_id="WP_269039083.1"
                     /transl_table=11
                     /translation="MRIPRPLLLLVVCGAACARPAQSGTDAPVNAPALPPDYTTARTGD
                     VHDFDYFAGGWTTAQRRLKARGVGSDEWEEFPATLCMTPYLGGMATVDELHFPTKGWAG
                     LTLRTFDLARRQWSIYWVSSETGLLGTPVVGGFEGDRGEFYGPDEDGGRPVAVRYRWTK
                     LDADHARWEQAFSYDGRAWETNWTAEFTRADPAAVCEAGRPRRQ"
     gene            complement(16415..17764)
                     /locus_tag="O0S08_RS11270"
                     /old_locus_tag="O0S08_11270"
     CDS             complement(16415..17764)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.5"
                     /locus_tag="O0S08_RS11270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_11270"
                     /product="cytochrome P450"
                     /protein_id="WP_269039084.1"
                     /sec_met_domain="p450 (E-value: 6.1e-33, bitscore: 113.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQPDAPPPRTFGLPLVGNTLGIMRDPIDFQRRGHRRHGPVFSAR
                     IFGTTLTFVDPVGAPELFEQVIRTPTDQLSLVAAYKHLVGRILGPELFTEIDKPMREGL
                     SVKYIGKHVGPTVAFVPQVLARRLPGDHGTVDGLRMANDVVLHVVAHYVLGHGGAERHA
                     DELAEAMHVLESDFSILGMMLPIETASARRRRAAFDRMIGLIEAEVRARRADRGQHDDF
                     LQFAIDHMSSDGAEHDDIRWLGLRVLGTIFGAHTNTAMSVASTLSDLVEHPEALARVRA
                     EIAALPADAPMDLAAMRTLVELHRAINESMRLRSNGGLWRMAMSDIDLGGYHLAKGSVV
                     GASMGLVNLDPARYQGSHEYRPARFEAMTTDNYQSPSVGSTPLQFGAFGTGRNLCSGRP
                     LAYAMLAAILVPLLRDYEWQVVRRPRRWFTLLTGGLSRPIGELSLSYRRR"
     gene            complement(18097..20067)
                     /locus_tag="O0S08_RS11275"
                     /old_locus_tag="O0S08_11275"
     CDS             complement(18097..20067)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024642.5"
                     /locus_tag="O0S08_RS11275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_11275"
                     /product="ATP-binding domain-containing protein"
                     /protein_id="WP_269039085.1"
                     /transl_table=11
                     /translation="MTRPLAPPESELVAEEHHVLEGLAAALPGARYFGRLRVRTAAGER
                     DVLLADRTWVGDELALIDWRTAPLAEVFFTCDLGDDYELERDDRQLRGVVVRRHLVHLH
                     DGALVGVDLADRRLRRGAGDLWHADDRPGPRVAPRSPTHRGRPLSPAKVELDPNQRAAV
                     ELAVERSLLVLGEAGFGKTTVALHRLAFLARAAHEARRPFRALMLVPTPGLQRLAVRML
                     AELGASRVQVDTFEQWVTAQARRLFPHLPRRLSATAGPGVRTFKRHPALRDLLPRIVAG
                     TAAMRDVAAGYREHPESLRDLLLHLYGDRELLAEAAAAAPDELGPSVLSDVLAHTKIQF
                     SATTERAMAHVDADRLRTLDGRSIDAGTPLADADSIDVEDFAVVFALHRRLTGGDRTPH
                     GALSHYQHLLLDEAQELAPIELELLGRAVAPDGTLTVAGDERQQVDASTAFAGWPAVLA
                     ELGRGDATTAALTVSYRCPPPIEDVARAVLDPAQRPRGVAHRDHLLVTRHDSPCHLVAA
                     LVDALLALTRDDPHVHVAVVCRHTETALSLHATLARALPARLVVEDGDFLFAPGVEVTT
                     VQDVKGLEFDVVVVPDLDAATYPDRPDARRALYVAATRPLHRLWLASAGPWSPLLPSWL
                     GGHVREDTHVSHDPSSERRAS"
     gene            20346..20840
                     /locus_tag="O0S08_RS11280"
                     /old_locus_tag="O0S08_11280"
     CDS             20346..20840
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS11280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_11280"
                     /product="hypothetical protein"
                     /protein_id="WP_269039086.1"
                     /transl_table=11
                     /translation="MWRIGRDSCVDLASDPLHCGSCDEAVDPGFVCVDGQPGCAAPQLL
                     CDGKCITPSSDDDNCGACGATCPSGRCAGLGLCLLEVGDPAVIPLSCAAMCEAAGMTCW
                     STGSEVGTAYYVGPCDELQTPILTCDAVPAEKDADQDSLCGFDCTCGLAGQACRCDAQA
                     P"
ORIGIN
        1 aggcactgct ctacaagggc gacgccgccg gggcgcgcga ccggctcgag cgcgccctcg
       61 cagtgtggga tcggacgctg gtcggcgatc acgatgcgac catggcgacg ttgatcttcc
      121 tcggcgcgag cgcgcagcag ctgggcgcgt gggaggccgc cgacgactac cagcggcgcg
      181 cccacgagat ggcgatccgg ctgcacgggg agcaccatcc gacgaccgcg gccttcttga
      241 gagattgggc caacagcgtc ctcaaccagg ccgaggcggc cgacgcaccc ggcgagcgcg
      301 agcgcctcgg ccggctcgcg ctcgaaaaag ccgaccgggc cgcggccgac ctcgaggcgt
      361 ccctcggggt cgagaacccg gagagcgccc aggcgcagct cacccggtgc cggacgttgt
      421 gggtgctgca ggagctgggc cgtgccgcct cggcctgcca gcaggcgctc tcggtgttgc
      481 ggcgggccca cggcgcagac agtccgctgc tgacggagtc gctgctcgtg ctcggcgtgg
      541 tgaaacacgc ccgcggcgag ctcgagccgg cccacgccgc gctcgcggag gcgctcgcgc
      601 gcggcgcctc gggcgacccg accttgctgg ccgacgtgca gttcagcctg gccaaggtcc
      661 tcggggagct ggggcagtcg cgccgcgcgg tcgagctggc ccgcgcggcg cggccagccc
      721 tcgccgcgga tgcgaggacc gtcaaatccc tggccgagct cgacgcgtgg ctggccgctc
      781 acgatcgccc ccggcgcgcg cgcccggtga agaagtgagg ccgttcgcgg cgctcacgac
      841 aatgcgtgtt tggtgagtat gtaatttttg atcaccgcgg tgcatcgggc gaccagcgcg
      901 tgtaccggat agagtgcaat gattctccga cggtccgcgc gtcactatcc ccccacttca
      961 tccgcggtcg cagagcgctg cgaatcggat cgaggcgagc gctagcgaat gaagcgcaat
     1021 tcgccgtcga cgacgacgcc gaacacgccg tccgcgaccg ggaagactgc gcccgcgacg
     1081 tcgccgagcc gcagctcgaa cagccggcgg ccgcgcggat cgaggccgag caaggcgccg
     1141 tcgtcttgca cgtacacgcg cccctggcga tcgacgatcg ccccgtacac cccccaacgc
     1201 aggccgtgcg cgaggtcggc ggtccacatc gatgccccgc gcggatcgag ccgggccacc
     1261 tgtcgctcgc cgacggcgat ccagcccatg tcatggtatt cggcgaacac cgccgggacg
     1321 gggtgctccc ctttcggccg cccctccggc gagagcagca gcgaacattc atcattgagg
     1381 ctgccgaccg cgcacacctg ggcgcgattg acggtcggca acaggtccgc gtcgcgcgga
     1441 cctgcccgcc acagccgctc gcccgacggt cgcacgcgac agaggccgtc gcccgcgtag
     1501 cacgccagag ccagcgaacc gtcggcgaac agcgccggcg gcaagatgtc gtaggcgccg
     1561 gcagaaagca cgcgcgccgt cggctcctcc cacacgatcc actcgccgcc aggggtcgtg
     1621 atgatcggcg cgcctgcgtg ggtcacgttg ggcgagatgc cggagtcgtc cggaccgcag
     1681 cagaggtgct cccaggacag ccaccgatcc tcgacgcggc cgtcggggtc gacgatcagc
     1741 gcggcgtggc gcacggtgat cagcgtacgg ccgccgcgga gcgccgtcgg cagcgagtgt
     1801 gacactcgct cctcgtcctc gtcctccgcg tcttcgccgg gcggtgggtc gtcgtcctcg
     1861 tcgggctcgg gcggcggcgt gagctcgagc tcgatggctc gcagcgacag cgaccagcgc
     1921 accgcgccgg cgagcgtcac gcggctgagg aagtcgccgt gcacgagccg caggtcgccg
     1981 tcgtcgccga gcaccccgcc gctcaccacg tgcaggtccg acggcgagcg cggcagctcg
     2041 agcggcggcg acagtcgcgg ctgcgtcggc ccgtcggcgg cgaacactcg acgattgccg
     2101 gcgtcgccgg ccgagcgcgg ccagagcgag tcggcgagcg tccgcgtcgg cgccatggct
     2161 cacgatagca tcggtcacga ggtgttcgca ggcgacctcg cgggcgaatg cgcgaggcga
     2221 tcggcccggc ctgcgacgag tcggcagcga tcgcgggcgc gggcggcctg gcggtggtaa
     2281 aaggcctcga tggtgcccgt tcccggcgtc ctggccgtcc tgctcgtcac cggcgtcctc
     2341 gtctacagcg cgagctgcac gctgcaggag cgggtgatct tcccgcggga atacgccaac
     2401 cagcgcgcgc tcgcgagtcc gcccgccggc gtcacgccgc tgtggagccc cgcggccgac
     2461 ggcacgcggg tcgaggcgtg gttcgtcccg gggcggggcg cgagcgccga gcggccgggg
     2521 ccggcggtga tgttctttca cggcaacggg gagctcatcg atcatcagct ggcgctggcg
     2581 gcgtcgtacg cggcccgcgg ggtgtcggtg ctgctgcccg agtaccgcgg ctacgggcgc
     2641 tcgcagggca agccgtcgca ggcggcgatc gtcggcgaca tgctgcggtt tcacgacgag
     2701 ctcgcggcgc ggcccgaggt cgaccgcgct cgcgtcgtgt tccacgggcg gtcgctcggc
     2761 ggcggggtcg cgtcggccct cgcggcggtc cgtccgccgg cggcgctgat cctcgagtcc
     2821 accttcacca gcctggcggc gctggcccgc aagcacggcc tgccggaggc gctgtgccgc
     2881 cacccgttcc gcaccgatcg cgtgttgccg gcgctgcaac ggccggtgtt gattctccat
     2941 ggatcggagg acgagatgat tccggtcgcg cacggtcgca gcctgcacac gagcgcgccg
     3001 ggctcgacgt acgtcgagct gccgggcggt cacaacgact tcccgcgcga tcgcccggcg
     3061 tacgagcggg cgctcgacgc gttcctgcgc gcgtcggggg tgctgctcga ggatcgccag
     3121 tgagcgcgga cctggccgcc ggtgacgacg cgtagagcgg cggcgggggc ggagcgtacg
     3181 aggcgatcgc atgcgcctcc gcatcctcga gccctgccgc gagaactggg acacgatgga
     3241 gccgacggag gtcggtcgac gctgcgaggc ctgcagccgc gaggtgcacg acttgaccgg
     3301 cctcaccgcg cgacaggcga agcggttgct gacgcgcgcg ggtccgcggc cgtgcgtgcg
     3361 cgtgcgggcc gacgaggacg gcctggcggt gttccgccgc gagccgccgc ggctcgctcc
     3421 tgcggcggcg gcgatggccc tcgcggcctg cgccccgcac acgcccgagg cgcagcggct
     3481 cgcgcccgcg gtcgaggtgg agccggccgc gcccccgcgg ccgtcgccgg tgatccccga
     3541 agccgcgcgg cggccggacg cgaccgcgga gccgggcccg ccgaagccgg tcaaggcgcc
     3601 cgcgaagaag cccgaacgcg agcgcgtgct catgggcgac ccgtgggatt gacggagtcg
     3661 cgcggcggcc gagagcgaga gcagggttcg tgatgcggtc actcgctccc gcggcgtcgc
     3721 cccgtgcgag cgaagaagtc gtccgcgaac gcgcctggcg tacgtcgcgg tgcgagcggc
     3781 ggcggaccga ggcgccggcg ctccggcccg cgagcgatcg ttcctgcggc gcagcgcaca
     3841 atctggacac gggcgaaaac gcgcgggaat agatccgcga gcgaagcgga cgggtcggcg
     3901 gagcgaggtc gacgggcctt cgcgaggtac cgggtgcgcg cggcctcctc atcgtgaata
     3961 ctgcgtaccc cgccatgaga cgcccttgct gtgctctcgc cgtcctgctc ctcctcgcgg
     4021 tcgggtgttc gcggagcggc ctgcaggacg ccagcgatct caccgcggac cagctcgagg
     4081 ccgcggggca gtcgcggtgt agcgtcgtca aagatccgga caagccgctc atcgtcgagt
     4141 ggtcgggcat ggacgcggcc gagctcgagg cccggctgct ccgcggggtg gtcgcggtcc
     4201 gctacgagga ttgcgagatg gaggtcctgc gcgggtgtac tgcgcccggg caatattcgt
     4261 acgcgcagac caccacgggc tccgagagca tccacatcgg ctcgctcgac gagctgttga
     4321 tcaatatccc gctcggcctg gcgcagctcg gcgggcgggt cgagcgcggt gaggcgctcg
     4381 agctcgacat ggtggtggtc ggccgctacg aggcgccgcg tccggcgtac acggcggcgg
     4441 agctgagcgg cgggcccgag tgcgcgcgcg cgacccacgt ggtcaccggc gtgagcctgg
     4501 gggcgtttcg cctgtcgtcg gtcgaggaca gcgcgcgcag cgggtccggg gcggggctcg
     4561 gcggggcgtc ggaggacacg atcgaggtgc tcaaggagtc gccgccgaac atgctcgagg
     4621 cgtgtgcgca ggtggccgcg gccgacgacc cgcggcgcaa cgtctgtacc gcgccgatcc
     4681 gcctcgaggt ggcgccgatc tcggcgcacg cggcggcgct ggccgaatca cagcagttcc
     4741 tgcggccgcc cgacctcgac aagcgcgagg tgcaatcgat ggacctgtcg ggcggcctgg
     4801 cggcgcatca ggcctacgac gcggcggtca aggtgcaggc cgaccggtgg gcgacgccgg
     4861 agcggcgcac ggaggcgtgg tgcgccctgg cggcgatcga gcaggacaac ccgtacctgg
     4921 cgcaggcccg cgagctgtgc gaccgctggc gcgatcacac gactgcgctg cgcgggagcg
     4981 aggcgcggat gatccgcgac tacgacgaat tgcgggtgct gctcgagctg cgcggcgtgc
     5041 cggtcgaggt ccaggagcgg gcggcggcca gcttcctggt gacgcactca gggctgtctc
     5101 cggaggcgta tccgcggatc cgcgctgtcg agcgggccaa gcggcgcctc ggtcgcggcg
     5161 accgcacgag cctgccgtcg ttctcggccg cggccgccgg cgagccgccc gccgtcgaca
     5221 gccaggtccg cacgagcctc gtcgaccgcc gctcgtaccg caaggcgctc agcatcgggt
     5281 ttcagccgcg gtggatcccg cagggctacg cgctcggcgg gacggtgctc ggtcgcgtca
     5341 attacgtgca cgaggtcggc ttcgaggtgg cctatgcgca atacgccggc tacggcccgc
     5401 gctggcgcta catcctggcg atggcccgct acgagcgggt ctaccgcccg cacaaggtgt
     5461 tccgcccgta catcggcgcg tcgttcgggg cgctcatccc gatcgggccg atggcctgct
     5521 cgcaggtgcc gcagccgtgc gcggcgcctg ccggggtggt gacgctgaac ggcggggcgc
     5581 gggtgtcgct gacgccgtgg ctgtcgctgg tggcccaggg gttcgcgggc gcgatgactg
     5641 cccggccgtt cttcgtcggc ggagtgtccg gggggatcga gttcacgatc cccaccggcc
     5701 gcgactggcc gcagtgagtc acgcccgcga ttcgccgcgg cgcccgtcgg gcccgccgcg
     5761 gctttcgcct gcaggccacg gtgcgacgcc ggtcgccgat caatcggtac aggtggcgat
     5821 gccgtcgtcg aaggtgcaat tcgccgtcag cacgatcgtt ccggccggct gttcgacggt
     5881 gatcttggcg ctggtgaagc tgatgtccag gattctctcg gtccacttgg tattggggca
     5941 gtcgggggcg cccgggatcg gactcacggg ctgtgcggtg gtgacatcga aggacacgtt
     6001 gccgttcttg atcgcgctcg cggggatcga ctggacaccc gtcaaggtca cctcggcggg
     6061 gttctgcccc ggcggttgtg tgctacccgc cgggttggtg caggtcgcag tcgggtcccc
     6121 cgtggcctcg agcgtgatca ggaggtcttc gttgccgagc ccggccaggg tgcccctcgc
     6181 ctccagcgtc acgccgaggt cctgaaagct cggcccggcg ttcttgccgc ccttgaagtg
     6241 cacgctggcg gccagggcca ccgaggtccc gatcacgccg gcgagcgaaa gagcggaggc
     6301 gatcgtaaag aacttgtttc gcatggaacg taccatcatg cagaacactg tgtccgagga
     6361 ttgcggcggg tccgggtgat ccgggcggca gttcgatgcc ggtcaccggc gcctgttcga
     6421 tgattggaag ccccggcagt gtgttctacg gggagccgcg gtggggcatg gacgcgtgct
     6481 accaccggga ccgcgaggtc cttgctgcgc tcgtgtcgtc gttcctcctc ccgtcggacg
     6541 agctgaggtt cggctccgga ctgcgcattg aaagcgaggt cgcggcgcgt gatcgccatg
     6601 ggcgaatgcg gggatcggcc acgggcgagg aggtccacca ggggccgggg gcggctcgct
     6661 ccgtcgcgct ccctgctggc gatggagctg tccgaagggt catgtcatga tacgccggcg
     6721 ccgggccagc gcgaccaggc cgaggagcat ccacgccgcg ctcgcgggct gcggtcgcgt
     6781 tgagcagttg caggcggagt cgtcgtccat ctgcccgccg cttgcggcgg ctccgctgtc
     6841 cgggggcgga gcggggcagt ccgaggggca gtcctccgag ttctccggcg ggtccgtgca
     6901 gatctcgtca ccacacaccg cgcaatcgtg cgggcagctc gcgatcgtct caccggcatc
     6961 acatacgccg tcaccgcaga cctcgccgcc ggtcgggtcg gccccgtctt gcgggcagtt
     7021 ctccggggtc tcgggcgggg actggcggat gccgtcgccg cagatgccgt cgtagtcgca
     7081 atcgtcgggg caatgggcgg agttctcggg cggctcgcag gcgccgtcgt ggtcgcaggg
     7141 gccgcagtcc tcgaagcaat tgtcctcgtt ctccggcgga acctggcagg tgccgtcgcc
     7201 gcacacgccg tcgtagtcgc agtcgcccgg gcagttctgc gggttctccg gcggctcgca
     7261 cacgccgtcg tcgtcgcaca ggcccgagtc ctcggggcaa ttctgcggcg tctcgccttc
     7321 atcgaggatg ccgtcgccgc aggtctgctc gcacgcgacg caggtcggcg aatcgtcgtc
     7381 gcaggtctcc cacggctgca ccacgccgtc gccgcagtcg atcgggtcgg ccaggagcgt
     7441 gaccgagaac ggaccgacgc aggccttgtt atcggcggcg tcgacggcac agtactgcca
     7501 ggtcagcgtg tcctcctcct tgcccttgta gggcacggtg aagccgacgc gccacagcgc
     7561 ctcgccgaac cagatcgacg gggcgatgaa cttgttcggg tcgccgtcgg ccagcgccag
     7621 caggtcgttc gggtcgtcga ggccgagcgc gaactccagg tacggcaggc ggcggttgtg
     7681 ggcggtgagc gtcgcgccgt cgccgatcag gtcgaggtcg ccgaggttcg cgtcgatctg
     7741 gaagtcgtgc cagcgcaccg gcgtcttcga gtcgtcgacg cgggccacga agcgggcttg
     7801 ctggccgaag tacatcaggg tgccgagctt gtcggcgaag ccgtcgtcgt agatccgcgg
     7861 gggcgtggtg tcgatcgcca cgccgtcggc agggtcgtcg cggccgaaca gcacgaagtt
     7921 cggcagcgcc gcgtcgcgcg tgaccactgc gacgtcctcg cgccggtcgt ggtcgaagtc
     7981 ggcgaactgc aggccgaacg tcgccgccag ctccggcacg atcgggaacg cggcgtcgag
     8041 cgggaccggc gcgggctcga ccgccgcgcc gttcttgttg aggagcagcc gcgagttcct
     8101 gtcgttggcg cccaggcgca ggccggtggt cacgaagtcg ggccggccgt cgttgtcgaa
     8161 gtcgagggtg gcggcgtcga agtcgagctt ggccgggttg tcggcggtcg cccagaagtt
     8221 gccggggttg tcggtgacgt agttgccggt cccgtcgttg agcaggatcg agttgcgccg
     8281 ggcgcaggtg ggcacgccca tgacgtcgac gcagttgccg ccctgaccgg cgccgtcctg
     8341 cagggtgacg aggtcgagga agccgtcgcc gttcagatcg gcgggcgtga acgcggcgtt
     8401 gacctgcttg gcgacgttgg ccgcgagcgc cgggatcgtc gaatgggtga aggtgccggc
     8461 gccgtcgttc ttcaggccga agccgaagcc ggggccgcgg ctcgagacga gcacgtcgag
     8521 ggcgtagtcg ttgtcgaggt cgacgagctc gacgtcgaac gaccaggacg cccaggtctc
     8581 catgcccatc ggcaggttca agtcgccgtc ctcgaagctg ccgtcgccgt cgccgagcca
     8641 caggcgcagc ggctggcccg gatcggtctg ctggccgtag ggctggctcg cgccccagtc
     8701 ggcggcgacg acgtcgaggt cgccgtcgcc gtcgacgtcg ccgagctcga ggtcgccgat
     8761 gctcttgccg gcgctcgcgg ggatgtcctg gcgcgtgaag acgccgtcgc cctcgttgag
     8821 gagggcgtag ctctggccgc cgaagttgac gccgacgacc aggtcggcgt cgccgtcgcc
     8881 gtcgaggtcg ccggccttga tcgcgtaggc gttgtcgggc tcgtcgaaca ggccggccag
     8941 ctcggtgaag cctgccccgt cgttgcgcag gagctggttg ggctgggcgt cctgggcgtc
     9001 tccgagcgcg tcgccggcgc tgttggcgaa cacgaggtcg acgaagccgt cgttgtcgat
     9061 gtcgaccagc tcgaccttct gagacacgaa gccggagtcg gagagctgca cgtcggggtc
     9121 gagctgccac ggggcagcgg ctgcgacgcg cgaggccaga gtgaccgcca cgaaggctgc
     9181 cggggaaggg cgggacatgt tcctcctgag gagcgctggc gacggcggcg aacgaagccg
     9241 gcctgcgggg atgcggccgc ggatcggcgc aacccatcat agccgggcag gcggcagtct
     9301 gttcacagga gtgcatggat ttcgtcgcga gcggtcgtcg tggcagcgag gcaaggccgg
     9361 caggagcgtc gggcctgcgc ggcgccgagc ttcgtcttgc atcaccggcc gcagtgcggg
     9421 agggacgcgc tgcccgggca agtgtgtgga cgaaccccgt gtcctgctcg tgcccgttct
     9481 tcctctgggg aggctgtcct cgaccaccgc gggatcgtcc gcctccacgc gcgggcttcc
     9541 gggcggccac gagggcacga gcgcggtgac cgtcgatttc gcctccaagc agcggaccga
     9601 cgcgtcgccg gctccgcggc tcgcggcgcg aagtttttgg aggtgacgac tgcggcgctc
     9661 gagccaatgc cgtcccggga tggagctcgt cacgccgggg cgcgcgctgt cgtcggcgca
     9721 gccacacgag gctgtcggtc ggtgactgtc gaggaagcgc cgcccggttc cgaagtcgct
     9781 gctttcttga ctggcttata agacatgtct ccagggacat tccatcgacg gcgcggcgcc
     9841 gtcagctcgc ggggcgcagg gcgagggcgc cgacgcgggc gccgtagcgg cggctgtggg
     9901 cgtaccagtc gatgtggccg ttgacgctgt tgacgatcgt ctcgacgtac gcggcgatcg
     9961 ccggctcgtc ggggtaggcg gccagcaggg cgcggcgccg tcagctcgcg gggcgcaggg
    10021 cgagggcgag ggcgttgacc tcgcgcagga gcgcgtggaa gcgggcgcgc agcgaggcgt
    10081 cgcggcggtc ggccagcagg aggacgttgt cgagctcggc gcaggccagc tccttggcca
    10141 gggagaagat gtcgttgacg aggatgacgt ggcggcaggc gccggtccgc agcagggcga
    10201 cggggtgacg ctcgcgctgg gcgggcgaga ggtcgacgcg cttgagcagg aggaacgact
    10261 cgagcgactg caaataggag atcgtctgct cgcggttgca caaataggtg gacagggtgc
    10321 cgcgatagtc ggcgtcgcaa tgcgcggagt gctcccaggt catggcctcg aagtagtcgc
    10381 gcatggtggc gacgaaccac cgcaggtcgc cgccctcgtg cacggcctcg gcgcggatgt
    10441 cgacgagggc ggcgcggaag gccgagaagc gggggaaatc ggccgccttg cgatcgagct
    10501 ccgggtcggc gggctggccg gcgagggccc gctgaaacgc cgcgagcacg ggggcgagct
    10561 ggtggtgcgc gagccagtcg gcgccgacgc ggatgtcgcc gaggttgtcg agggcgtcgt
    10621 cgagggtgaa gatgaaggcc tggaggcgga tgaaccaccg cgccctggcc ggacggacgt
    10681 cgggcaacgt gtgggccgac agggcggcca gctgcgacag gcggaacttg gcggcgtagc
    10741 gcccccccgc gtcgatgagg ccgatccgct cggcccagcg cacgcactcg tcctcgctgg
    10801 cgtcgatctc cgccggcgtg ccgaccggct cggcccgccc gtggcccggc acctccatgc
    10861 gcaccagagt gccggtcaga cgattgccgc gaacagtccc gaggtcgaag tcgatgccag
    10921 tcatgatgtc cggtcagcga ccgcgagggc cgcaacggat cagcgacgtc cgggcgagga
    10981 acgactcggc ctgcgatcgc cgacgacgac cagaggtcgc tgcggtcggt ttcgtcggca
    11041 gcggtgattt tcgcggagag ctcgccggcg aggccgcacg gattgcgggc gactcgacgt
    11101 cggggctcgg cctgcgaggc gacggtcgcg gtttcggccg cctgcgcgag cgttcaccgg
    11161 cgaatcgatg gacaaggagc gcgggcggct tggctgcgtc cggctggacg gctacgctcg
    11221 cgcaatgagc tccggaccgc tcgagcacgc cgaacggcga cgcgcgcaga tcgaggaggt
    11281 ccgcgcgctg agggccgggc tggcggcgtt gatcgcaggg cgaacgacgc gcgaggagct
    11341 gtcgcggtgg ctccgcgagc tgtggccgcc gggcagcggg cagggcggtc cgttcctctg
    11401 gcagcccgcg gcgtgcgtgt acgattcgct gctgagcctg aaccggcgct ggggcgagca
    11461 ggagctggtg cgggaggtcg agctgcgggc gtacctgcgc tggctcggcg agggcgagtg
    11521 ctgcttcacg gacgacggtg actcgctgtt cgtgctgcac cgcgacatcg acgagctcgc
    11581 ggcctgggcg ggcgtcgagg cggtgcgctg gtggcactcc gggctcggct ggtggacgtc
    11641 gctgcaattc gggtcaccgg cgagccgccg ggtcttcgtc gtccactcgg cgctcgagcg
    11701 cccggacgtg gtgggttttc atccgcagcg aggggtcgcg cgcgaggagg ccatccgcga
    11761 gctgttcgag gtgctggcga tcgacgacgc cgacgtgacg cgcgtcgatc cgcagatcga
    11821 cctcgaacga ttgccgcgat gggcgctgat ccgccaggac gacaacggca atcgcttcga
    11881 gatcgccagg ttccgcagct acaccaaggc ttacgcgcag gagcggacgc tgacggcccg
    11941 cgggcacaag cagctgtact gggtcgagcc ggcctagccc ggatttctca ccacgggaag
    12001 gaattccggc cgtacttccc gagttcgagc gggtgtgaaa cgattgctga ccacccaggg
    12061 gtacggccgg aacacgacaa ggtgtatccg caccgagttc gattttcaac cggccgggcg
    12121 gagacgtgtc gagggcgcct ttgacggcgg acgggtcagc tcggacggcg gcctgctgtt
    12181 gctgcgcgag ctgaccgaga gttcaggtgt gttccgggac ttcgcctcct gcttccggga
    12241 ccaccgcgac ccgagccgcg tcgagcacac cgtcgaggaa ttgctcgcgc agcgcgtgct
    12301 gggcctgctg tgtggttacg aagacctgaa cgaccacgac atgctccgcg atgatgcctt
    12361 gctcgcgctg gcggtaggca agatcgatcc gaccggcgaa cagcgcaagc gggaacgcga
    12421 ccggggtcac gcgttggccg gcaagagcac gctgaaccgt ctggagctgg cgaagcccac
    12481 ggtggccggc gacgagcgct acaagaagat cagctacgac gaccacggca tccagcgcct
    12541 cttcgtcgac acatttctcg ccgcgcacga tcggccgctc gccgagatcg tcctcgatct
    12601 cgatgcgacg gacgaccccg tacacggcaa gcaggagggt cgcttcttcc acggcttcta
    12661 cgacagctac tgctacctgc cgctgtacgt cttctgcggc gacttcctcc tcggcgccgc
    12721 gctgaacacc gccgacaagc agccagtgag cggcgcggtc gaggagctcg agaggatcgt
    12781 cagccagatc ctcgcccgct ggcccgacgt ccgggtcatc gtgcgcggcg attctggctt
    12841 ctgccgcgac gaggtcatgc gctggtgcga ggacaacggc ctcttcttcg tcctcggcct
    12901 gcagaagaac tcgcgcctga tcgtcgagat cgaggacgag atgaagcagg cccgcgccat
    12961 ctccgagcag accggcaagg aggcgcgcgt tttcaaggat tttcgctacg agaccaaccg
    13021 gacgtggtca cgagagcgcc gggtggtcgg caaggcggag tacacgacgg acaaggagaa
    13081 cccgcgcttc gtcaccacca acctctcgca tgacgagtac gacgcgcgct cgctctacga
    13141 ggacctctac tgcgctcgcg gagacatgga gaaccggatc aaggagcagc agctcggcct
    13201 ctttgccgac cgcaccagcg cccacacgct gcgcgccaac cagctccgcc tgtggctctc
    13261 gtccgtcgcc tacatgatcc tcaacgagct ccgccgactc gccctcgccg gcaccgagct
    13321 cgcccacgcc caagtctcca cgatccgcac gcggctgctc aagatcggcg ccatcgtcac
    13381 cgcatcggtc cgcaggatcc gcgtctccct aagctcagtc ttcccactcc agcacgtgtg
    13441 gtggcgcgtc ctcgagaacc tccaccgcca tcacgtcatg agacgctgac ggccctcgcc
    13501 atccgtcaca caatggtgcg ctgcgctgcg cgccggggtt cgtctgtcct tatgctcagg
    13561 tcacccaaaa cgcgtagcca gctttgtaat ccctcttaca gctcgatctc gcgccagccc
    13621 cgagcctaac gagcgcggcc tcgcggctca cgtcgacggc atccaacaat ctcccgccac
    13681 gccgcctggc agccgcctgg cgggccccac ctatccgtgg tgagaaatcc gggctagccg
    13741 gcgccccggc cggggcctcc gaaggttgac ttcgagaccc gcggcggcgg aagtcgcagc
    13801 aagacgccgg gtccgccgat cgctcgggaa aacaggagtg cggcggggcg cgagagcgag
    13861 cggcatgagg ccgcgagggt catgaaaaat tcttcgacgg gaatcggcgc cgccggagat
    13921 gggaccgtca tgcacacgcg ccctccatca cgtctttcgt cctcgcccct gaaagtgcgg
    13981 cgtgggacgg tctggacgac gacggcaccg cctccggcgc cacggccgcg gcctcgccga
    14041 tgacgacgag cccgaccgac gaccaccacc acgcccgacg gcgacacgac aaacctggca
    14101 accggcgacg acgacgctga cggtgatacg accggcagcg acgggtcgtc ctgattcgga
    14161 gttcattcca atgcgatccc tacgcgccct ctattgcttc gccatccttt taactgcctg
    14221 ccctgacccg acctcggcca cctcggccag cgattccggt gacgactcga ccaccggtgc
    14281 gaccagcgag ccgaccaccg gtgcgaccag cgatccgacc accggttcga ccggcgatga
    14341 cgccaccggc gtggataccg agcagtccgt cgctccggtc gacctcgcct gcgacctcat
    14401 gcgcgaggcg tgcgagcggc aggtcgcgtg cggacacgcg atcgtcaaca acaaccccgg
    14461 cggcgtcgag gcctgcctcg cggagcagcg gtgcgaaact gtgggcgagc tgctcgactt
    14521 gccgaacatc gagctcgacc ccgacgccgt ggaggcgtgc atcgcggcgc tcgaagccgc
    14581 gagctgcggc gaactcgtcg cgcacgggct cgagatcgat ccgagctgct cgctatacct
    14641 cgccggcacc ctcggcgagg gcgaggcctg ccacggcggt accgtctccg actgcgcgcc
    14701 gggtctgtcc tgcgtgttcg agggcggcgc ttgccccggc acctgcgcgg ccccgcccgc
    14761 gccttgcagc gagggatcgt gcggcgccga cgcgttctgt accgtggacg gcacgtgcca
    14821 gcctcgggca gcgctgggcg aggcgtgcga cgagacgaac atcgagttcg acaacctgag
    14881 cgacagggct tgcgcggccg ggagtcattg ccaggactcc gtctgtgtgg ccgacctcgg
    14941 cgccggcgcg cagtgcggcg gactggacgt gcacgcctgc ggcgacgggg cgtgcgtgtg
    15001 cgccgatctc gagaattgcg acgagacggc cgatttcgcc tgcgggcccg tgcgcggggc
    15061 gggtgagccg tgctcgaccg ccttcgattg cgccgagggc ctctattgcg acttctacgc
    15121 cgggagccgc tgcgccgcgc gcggggggcg aggcgaggcg tgcaacgatt cgttcggcgc
    15181 ctgcctccat tcgctcgcgt gcgccgacgg gacgtgcgcc gacgaacagg agagcgtctc
    15241 ggacgtgtcc ttgctcgagg aggacgagag ctgcatcggc ggcggctcct gcccgctcgg
    15301 cacggcgtgc acttgtgacg acgcggactg cgtcgacaag cactgcctgc cagcgcccgg
    15361 cctcggggag agctgcgaag cgcaggactt cgacggctac tcctgctccg aaggcctgtg
    15421 cgacatcctc gccagccaca tctgcgtgct cccgggtgcc gcgggggagg cctgccccct
    15481 ggacggcttg accttcgcct gcgcctcgct cttctgcatc gagggccatt gcgcgtccgt
    15541 ggagcagacg ctctgccagg agtgacgatc gttcggccgc ggtccgcaag gggccgccgc
    15601 ggtcggggtg ggtgaccagg gcgcgctggt gaagggctgc gcggatctcc gcgacagtgg
    15661 cctgagcctc aaggcatggg agacgcgctg tgacagcagg tgtcgcgcgc ctcgggtcgc
    15721 gcgcacgtgg agccgctcac tggcgcctgg ggcggcccgc ctcgcacacc gcggccgggt
    15781 cggcgcgggt gaactcggcg gtccagttgg tctcccaggc gcggccgtcg tacgagaagg
    15841 cctgctccca gcgggcgtga tcggcgtcga gcttggtcca gcgatagcgg actgcgaccg
    15901 ggcggccgcc gtcctcgtcg gggccgtaga actcgccgcg gtcgccctcg aagccgccga
    15961 cgacgggggt gccgagcagg ccggtctcgc tgctgaccca gtagatcgac cactgccgcc
    16021 tggcgaggtc gaaggtccgc aaggtcaggc cggcccagcc cttggtcggg aagtggagct
    16081 cgtcgacggt ggccatgccg ccgaggtacg gggtcatgca cagggtcgcg gggaactcct
    16141 cccattcgtc gctgccgacc ccgcgggcct tgaggcgccg ctgcgcggtc gtccacccgc
    16201 cggcgaagta gtcgaagtcg tgcacgtcgc cggtgcgcgc ggtggtgtag tcgggcggca
    16261 gcgccggtgc gttcacgggg gcgtcggtgc cggactgcgc ggggcgggca caggccgcgc
    16321 cgcagacgac gaggaggagc agcggtcgag gaatgcgcat gccgccggcg aacctctcac
    16381 acgcgctcgc gccgggtcaa gcgaggcccg cgcctcagcg acggcgatag ctcaggctga
    16441 gctcgccgat cggtcgggac aggccgccgg tgagcagcgt gaaccaccga cgcggcctcc
    16501 ggacgacctg ccactcgtag tcgcggagca gcggcacgag gatggcggcc agcatcgcgt
    16561 aggcgagcgg cctgcccgag cacaggttgc ggccggtgcc gaaggcgccg aattgcagcg
    16621 gcgtggagcc gaccgagggg ctctggtaat tgtcggtggt catcgcctcg aatcgcgcgg
    16681 gtcgatattc gtgcgagccc tggtagcgcg cggggtcgag gttgacgagg cccatgctgg
    16741 caccgacgac gctgcccttc gccaggtggt agccgccgag gtcgatgtcg gacatcgcca
    16801 tgcgccacag gccgccgttg ctgcgcaggc gcatgctctc gttgatcgcg cggtgcagct
    16861 ccacgagcgt gcgcatggcc gcgaggtcca tcggcgcgtc cgcggggagg gcggcgatct
    16921 cggcccgcac gcgggcgagc gcctcggggt gctcgaccag gtcgctcagc gtcgaggcga
    16981 ccgacatcgc ggtgttggtg tgggcgccga agatggtgcc gaggacgcgc aggccgagcc
    17041 agcggatgtc atcgtgctcg gccccgtccg aggacatgtg atcgatggcg aattgcagga
    17101 agtcgtcgtg ctgcccgcgg tcggcccggc gcgcccgcac ctcggcctcg atgaggccga
    17161 tcatgcggtc gaaggcggcg cggcggcggc gggccgaggc ggtctcgatc ggcagcatca
    17221 tgccgaggat gctaaagtcg ctctcgagca cgtgcatcgc ctccgccagc tcgtcggcgt
    17281 gccgctcggc gccgccgtgg ccgaggacgt agtgggcgac gacgtggagg acgacgtcgt
    17341 tggccatgcg caggccgtcg accgtgccgt ggtcgccggg cagccgccgc gcgagcacct
    17401 ggggcacgaa ggcgacagtc ggcccgacgt gcttgccgat gtacttgacc gagaggccct
    17461 cgcgcatcgg cttgtcgatc tcggtgaaca gctcggggcc gaggatccgg ccgaccaaat
    17521 gcttgtaggc ggcgacgagg ctgagctgat cggtgggggt gcgaatgacc tgctcgaaca
    17581 gctcgggcgc gccgaccggg tcgacgaagg tcagggtggt gccgaagatc cgcgcggaga
    17641 agaccgggcc gtggcggcga tgcccgcggc gctgaaagtc gatcgggtcg cgcatgatcc
    17701 cgagagtgtt gccgacgagc ggcaggccga aggtgcgggg cggaggagcg tcgggctgcg
    17761 gcacgcgagg accgtagcag tccgcggcga ggcgcgcgtg cggctggcga aacccacctc
    17821 gatcgcgcgg aggcccgggg tcgcgtgcga ggggtccgcg aggatgccgt gcgtttcgtc
    17881 aagcatcgac gcgcggcccg aaccgcgttc acagcgaacg ggttcgactc gaccatcctt
    17941 gcgccgggtc gcgcggcgag gccgggcgga gcggccaggg gcgattcgct ccgccaggga
    18001 agcagccggg cggctcgcgt cgttctcgag atgtccctgg ggacagggag agccaggcgc
    18061 aggttcggtt cgtacagctg tccttgggga caggtgtcac gaggcccgtc gctcggacga
    18121 aggatcgtgg gatacatggg tgtcctctcg gacatgtccc ccgagccatg acggcaagag
    18181 cggcgaccac gggccggcgc tggccagcca cagccggtgc agggggcggg tggcggcgac
    18241 gtagagggcg cggcgggcgt cggggcggtc ggggtaggtg gcggcgtcga ggtcggggac
    18301 gacgacgacg tcgaactcga ggcccttgac gtcctggacc gtggtgacct cgacgccggg
    18361 ggcgaacagg aagtcgccgt cctcgacgac caggcgggcc gggagggcgc gggcgagggt
    18421 ggcgtggagc gacagggcgg tctccgtgtg gcgacagacg acggcgacgt ggacgtgcgg
    18481 gtcgtcgcgc gtgagggcga gcagggcgtc gacgagcgcg gcgacgaggt ggcaggggct
    18541 gtcgtggcgg gtgacgagca ggtggtcgcg gtgggcgacg ccgcggggcc gctgggccgg
    18601 gtcgagcacc gcgcgggcga cgtcctcgat cggcggcggg cagcggtagc tgacggtgag
    18661 cgcggcggtg gtggcgtcgc cgcgcccgag ctcggcgagg accgcgggcc agccggcgaa
    18721 cgcggtcgag gcgtcgacct gctgccgctc gtcgccggcg accgtgagcg tgccgtcggg
    18781 cgcgaccgcc cggcccagca gctcgagctc gatcggcgcc agctcctgcg cctcgtcgag
    18841 cagcaggtgt tgataatgcg acagggcgcc gtgcggggtg cggtcgccgc cggtgagccg
    18901 gcggtgcaat gcgaacacga ccgcgaagtc ctcgacgtcg atcgagtcgg cgtcggcgag
    18961 cggggtgccg gcgtcgatcg agcggccgtc gagggtcctc agccggtcgg cgtcgacgtg
    19021 ggccatggcc cgctcggtgg tggcgctgaa ctggatcttg gtgtgggcga ggacgtcgct
    19081 caggaccgag ggaccgagct cgtccggggc ggcggccgcc gcttcggcca gcagctcgcg
    19141 gtcgccgtag aggtgcagga ggaggtcgcg caggctctcc gggtgctcgc ggtagcccgc
    19201 cgcgacgtcg cgcatggccg cggtgccggc gacgatccgc ggcaggaggt cgcgcagggc
    19261 ggggtggcgc ttgaaggtgc ggacgccggg gccggcggtc gcgctgaggc gccgcggcag
    19321 gtgcgggaac aggcgccgcg cctgggcggt gacccattgc tcgaaggtgt cgacctggac
    19381 gcgcgaggcg cccagctcgg cgagcatgcg caccgcgagc cgctgcaggc ccggggtcgg
    19441 cacgagcatg agggcgcgga agggccggcg ggcctcgtgg gcggcgcggg cgaggaaggc
    19501 gaggcggtgc agggcgacgg tggtcttgcc gaagccggcc tcgccgagca cgagcagcga
    19561 gcgctcgacg gcgagctcga cggcggcgcg ctggttgggg tcgagctcga ccttggcggg
    19621 cgagagcggg cggccgcggt gcgtgggcga gcgcggggcg acgcgcgggc cgggccgatc
    19681 gtcggcgtgc cagaggtcgc ccgcgccgcg gcggagccgg cgatcggcga ggtcgacgcc
    19741 gacgagcgcg ccgtcgtgga ggtggacgag gtggcggcgg acgacgacgc cgcggagctg
    19801 gcgatcgtcg cgctccagct cgtagtcgtc gccgaggtcg caggtgaaga agacctcggc
    19861 gagcggggcg gtgcgccagt cgatcagcgc gagctcgtcg cccacccacg tgcgatcggc
    19921 gagcaggacg tcgcgctcgc ccgcggccgt gcgcacgcgc aggcggccga agtagcgggc
    19981 gcccggcagc gcggcggcga ggccttcgag cacgtggtgc tcctcggcga cgagttcgga
    20041 ctccggcggc gcgagcggtc gagtcatggg cgaaacatga caccgcggac ctgtcgcgcg
    20101 agcgcggggg cggacgagag aggtgcggtt cctccgcggc aggacggcga gcgcgagagg
    20161 ttggcggctg gctggcggtg agaatggtgc tatggttgga tcggtgggcg gtcgaggcga
    20221 cgtattcgcg ggttgcgagg tacggccgcg cgaatgacga gaatcgagcc cggagatcgc
    20281 cgccggccgg ggtttccgag cggccggaga tcgcttcggg gtggcgaggc gggtggtgtt
    20341 cgcaggtgtg gcgaatcggg cgcgattcct gcgtcgacct ggccagcgat ccgctccact
    20401 gcggcagctg cgacgaggcg gtcgaccccg gcttcgtctg tgtcgacggc cagcccgggt
    20461 gcgcggcccc gcagctgctg tgcgacggga agtgcatcac gccgtcgagc gacgacgaca
    20521 actgcggagc gtgcggcgcg acgtgcccgt ccggtcgctg cgccggcctc gggctctgcc
    20581 tgctcgaagt cggcgatccg gccgtgatcc cgctgtcgtg cgcggcgatg tgcgaggccg
    20641 cgggaatgac ctgctggtcc acgggctcgg aggtggggac cgcgtattat gtcggcccgt
    20701 gtgacgagtt gcagacaccg atcctcacct gcgacgcggt gccggcggag aaggacgcgg
    20761 accaggacag cctctgcggg ttcgactgca cgtgcgggct cgccgggcag gcctgccgtt
    20821 gtgacgccca ggcgccctga gtcgggcgcg ggtgcacccg tcgacgcggc gcgaggctct
    20881 ggtaccctca cggggtggtg cgtcctgaag acacggacga gcag
//
