LOCUS       NZ_CP114040            24454 bp    DNA     circular CON 26-AUG-2024
DEFINITION  Nannocystis poenicansa strain FL3 chromosome, complete genome.
ACCESSION   NZ_CP114040
VERSION     NZ_CP114040.1
KEYWORDS    RefSeq.
SOURCE      Nannocystis poenicansa
  ORGANISM  Nannocystis poenicansa
            Bacteria; Myxococcota; Polyangia; Nannocystales; Nannocystaceae;
            Nannocystis.
REFERENCE   1  (bases 1 to 13228663)
  AUTHORS   Ahearne,A., Stevens,C. and Dowd,S.
  TITLE     Minimal conservation of predation-associated metabolite biosynthetic
            gene clusters underscores biosynthetic potential of Myxococcota
            including descriptions for ten novel species: Archangium lansinium
            sp. nov., Myxococcus landrumus sp. nov., Nannocystis bai
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 13228663)
  AUTHORS   Ahearne,A., Stevens,C. and Dowd,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-NOV-2022) Biomolecular Sciences, University of
            Mississippi, Faser Hall 407, Oxford, MS 38655, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2021
            Assembly Method                   :: IPA v. 10.1.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 250x
            Sequencing Technology             :: PacBio Sequel IIe
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_026965555.1-RS_2024_08_26
            Annotation Date                   :: 08/26/2024 12:45:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,229
            CDSs (total)                      :: 10,129
            Genes (coding)                    :: 10,068
            CDSs (with protein)               :: 10,068
            Genes (RNA)                       :: 100
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 9 of 61
            Pseudo Genes (incomplete)         :: 52 of 61
            Pseudo Genes (internal stop)      :: 2 of 61
            Pseudo Genes (multiple problems)  :: 2 of 61
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:28:22
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2763480
            Orig. end                         :: 2787934
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP114040.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24454
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="6"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..24454
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24454
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14454](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14454)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            516..1208
                     /locus_tag="O0S08_RS10510"
                     /old_locus_tag="O0S08_10510"
     CDS             516..1208
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS10510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_10510"
                     /product="hypothetical protein"
                     /protein_id="WP_269038946.1"
                     /transl_table=11
                     /translation="MGGTIVSPRMLCTLSAVSAVACPVNTSDLSGGPVSTSGTDESMGQ
                     TELSDGPADDTTSPPASDESQLVYGDAPAAGWRVKIDGADVDLFSREEVHAGTAAIAVT
                     FTGEWGSVRFDATPPLAAEAYTAVEFWIHGGSAGGQEIEFAVVARIGVAELWGASTERR
                     ITAQPNVWRRERVELSSLGSPVNVGILAWLSTSGGEQPIFYLDDVTLIGRPPEDASATA
                     GHALPLGP"
     gene            1406..1750
                     /locus_tag="O0S08_RS10515"
                     /old_locus_tag="O0S08_10515"
     CDS             1406..1750
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429654.1"
                     /locus_tag="O0S08_RS10515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_10515"
                     /product="lectin"
                     /protein_id="WP_269038947.1"
                     /transl_table=11
                     /translation="MTDRLDPGQFIKRNTPDDRITSANGRYSLIMQNDGNLVIYNQGSA
                     IWATNTAGTDGETAVMQTDGNFVLYRVNGTPLWASNTAGRPVSYVIMQDDGNLVVYQTL
                     ATWASNTAGQ"
     gene            complement(1764..4271)
                     /locus_tag="O0S08_RS10520"
                     /old_locus_tag="O0S08_10520"
     CDS             complement(1764..4271)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (79-394). E-value:
                     1.3e-24. Score: 78.9. Matches aSDomain:
                     nrpspksdomains_O0S08_RS10520_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1109: 8-amino-7-oxononanoate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012382.5"
                     /locus_tag="O0S08_RS10520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_10520"
                     /product="bifunctional aminotransferase class I/II-fold
                     pyridoxal phosphate-dependent enzyme/GNAT family
                     N-acetyltransferase"
                     /protein_id="WP_269038948.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.1e-22, bitscore:
                     79.0, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDASSFREAIFQVHSHGRDRGHYFLSAEDERFDDRHIRVSGKRLL
                     SFGSCSYLGLEFDPRLIDGGVEAYRRYGTQTSFSRGYLSCPLYPELEEDLLPRIFGVPR
                     VLLLPSTSIAHHVVMPALLAENDAIVCDHQVHRSVDDAITLQCARSGADKVVVKHGELD
                     RALDIVARLARTHHHVWFACDGVYSMYGDSLPLGFLHDLLAVAPNVRLFVDDAHGMSWA
                     GDRGCGHFLSRFPLGERVVLVTSLAKAFATGGGVIVVQDRRLLETARLVGGPFSFSGPL
                     RPGDLGASIASARIHLSPELAVLQAALRARIDRANALCRALGIPLVIENEAPIFFIALG
                     RVEAVYLMAERLREHGFHVNVSGFPAVPASRGGIRIAINAIHSEAQVDALFRAIAEHLP
                     AVLAAVGVTRDEVEEQFEGVLPPFLRAARPLASAVRQLPERHPQPADALTVETHASIEQ
                     LDARVWDAHLGDLSYIDARSMRAVERVFHGGHALREHRWSFRYVLVRRGDELVAAAPFT
                     TLLMKDDTFMSAAVSAALERERLADPYLFTSRAVVMGDMASEGEHMFLAPGAGRSAALI
                     ALAEAGVAEMKAQNCSTLVLRDLADDPELVRVLTGQGFVPVPLIERYLVQLDWRGEDAF
                     IDALASNGQRRHVRAVHQQSPLFDVEVWDSRSAAADDELRRLYALYRRMAAKNLRINIF
                     PLPPELLRAQLESGSWEFLLLRRRGGGPVVAWAAARPAGCEYRGLYCGVDYDEFPAGKI
                     NPYRQLLWQLVRRAGRLGCERLHLGMGARQEKTRFGATASPALALVRADDAYRATRLQE
                     FVTRTALHVQPSSAGRGARAPRP"
     misc_feature    complement(1995..1997)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        complement(3090..4034)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_O0S08_RS10520_Aminotran_1_2.1"
                     /evalue="1.30E-24"
                     /label="O0S08_RS10520_Aminotran_1_2.1"
                     /locus_tag="O0S08_RS10520"
                     /protein_end="394"
                     /protein_start="79"
                     /score="78.9"
                     /tool="antismash"
                     /translation="RGYLSCPLYPELEEDLLPRIFGVPRVLLLPSTSIAHHVVMPALLA
                     ENDAIVCDHQVHRSVDDAITLQCARSGADKVVVKHGELDRALDIVARLARTHHHVWFAC
                     DGVYSMYGDSLPLGFLHDLLAVAPNVRLFVDDAHGMSWAGDRGCGHFLSRFPLGERVVL
                     VTSLAKAFATGGGVIVVQDRRLLETARLVGGPFSFSGPLRPGDLGASIASARIHLSPEL
                     AVLQAALRARIDRANALCRALGIPLVIENEAPIFFIALGRVEAVYLMAERLREHGFHVN
                     VSGFPAVPASRGGIRIAINAIHSEAQVDALFRAI"
     gene            4568..5236
                     /locus_tag="O0S08_RS10525"
                     /old_locus_tag="O0S08_10525"
     CDS             4568..5236
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS10525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_10525"
                     /product="hypothetical protein"
                     /protein_id="WP_269038949.1"
                     /transl_table=11
                     /translation="MALDLAPSFQALLDAFRSAGGPLHTTGPLAAVIDCDGGAPGIDAW
                     ADDVRSAGGGHLVEGASLLAGIPWHVRAALDLEWQDETGRLDGTTLDIDVSHPWRAFLR
                     RARLAPPGALANDPFAFVLSIHPVTGSTARCIARWPPAATRPELVYHSGGGELVPLRLS
                     VREYFEQVLVARGWGGWELAFAAEPLRDPVQVDAQVLAPLRRRLGERFPELDLAALKAR
                     "
     gene            complement(5554..5847)
                     /locus_tag="O0S08_RS10530"
                     /old_locus_tag="O0S08_10530"
     CDS             complement(5554..5847)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS10530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_10530"
                     /product="hypothetical protein"
                     /protein_id="WP_269038950.1"
                     /transl_table=11
                     /translation="MARLTHVALALLLVAFGCAGDTAGGGDTTASDDTTTTGDSETGGD
                     DTPQATALPLEVLGPAGTLVAVHIDVPDDLAGAPGAELALTVHNVDAWLVPL"
     gene            6199..7119
                     /locus_tag="O0S08_RS10535"
                     /old_locus_tag="O0S08_10535"
     CDS             6199..7119
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1213: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF046294.1"
                     /locus_tag="O0S08_RS10535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_10535"
                     /product="integrase core domain-containing protein"
                     /protein_id="WP_269038951.1"
                     /transl_table=11
                     /translation="MIRPSRRHGLAAVREPRLCEAFLEYAQARGFVIDVARVRRPQDKA
                     RVERAVRDVRDDCFGGERIRDLAAARERAERWCRDEYGVHRHSTTGRMPREHFLNVEVP
                     VLLPAPEQPYDVPRWCTPKVARDHFVQVERALYSMPTRLIGRTLQARVDRSSVRFYDRS
                     TLIRICRRLPPGGRSINPEDFPKEKRAYAMRDIEFLQKQADELGPNIGAYVRRLLSGPL
                     PWTSMRTVHGVRGLAERHGVAVVDRCCGIAIAADMLSLKRLRAMVERDVKPQPIPLDRP
                     TPPARFLRPAQIYALSANTKHGEPS"
     gene            7116..7904
                     /gene="istB"
                     /locus_tag="O0S08_RS10540"
                     /old_locus_tag="O0S08_10540"
     CDS             7116..7904
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="istB"
                     /gene_functions="other (smcogs) SMCOG1151: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003920682.1"
                     /locus_tag="O0S08_RS10540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_10540"
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="WP_269037240.1"
                     /transl_table=11
                     /translation="MIDTISPDLKAILKRLKLSPLLSTLPDRLALARQQKVPHQDFLLT
                     LLTDEVSRRDSISAQLRGQKARLDPEHQLEGWDSTTRVHFDQELWAELCSLRFVEARAH
                     VALVGPVGVGKTFLAHALGNAACRRQYSVLAYRCDRLLKNLRHARLDGSYDAELRKILA
                     VDVLILDDFGLDAMDATESRDAYEIFTERHRHGSIIVTSNRGPDEWLAVFADPVRAQAA
                     IDRFTSNAYDLVIEGESYRSRQKPSLTRPPKTGSRSRTRA"
     gene            8016..9197
                     /locus_tag="O0S08_RS10545"
                     /old_locus_tag="O0S08_10545"
     CDS             8016..9197
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS10545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_10545"
                     /product="hypothetical protein"
                     /protein_id="WP_269038952.1"
                     /transl_table=11
                     /translation="MQSRPSLSLLLSLAVASCGGDPNQDDGATSTGSTGEPGTTTTDAS
                     EPTGSTTDAPTGGTTGDAHVVPEFGGTFTVIGTADDGLHAVRDLEFNPAAPEQLWTFNM
                     LSHGVVIYFDPGAPQQTSEERIDAYGQHFMAYVSSAAFGDLDTFATCQESRNEWNVGPQ
                     DPDDFMGPALWPADLDIFAKVGQEFPPNGQEGSHLDMLHQSPLCMGIAHEAGNAFWAFD
                     GMHGNIVRYDFQADHGPGGGDHSDGIITRYIDVTVTRLGNIPGHMEFDHATGMLYIVDT
                     GAGRLLRLDTATGTNIGTLPGDWDGAEYTGVEGADVQVLVEGLDEPSGLALHEGRLFVS
                     EHGTGDIVAFDLDGQEIDRMTTPADRIMGITIGPAGDLWYADAGADEIVRVDE"
     gene            complement(10001..13054)
                     /locus_tag="O0S08_RS10550"
                     /old_locus_tag="O0S08_10550"
     CDS             complement(10001..13054)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.5"
                     /locus_tag="O0S08_RS10550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_10550"
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_269038953.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 4.2e-161,
                     bitscore: 536.5, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 3.1e-13,
                     bitscore: 49.4, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 6.1e-46, bitscore:
                     156.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPFVLVRTPVCSIEDYQALAGSPAGPPDSLDRAAQWASPPGRRTM
                     VADRDWVRDALAIASPKLHAALASDVLAPRKGRAARQKLLAYLIRMSTRPTPYGLFSGV
                     ALARWGERTDLALGDSPPILRTRPDMEWLYGVVDRLERRREVLAYLRVTANPLAWFAGE
                     RVFLCDGGSLAPDTRRISIRASGPVRLALRLSRAPVPYCELVEQIQRAHDAPRERIEQF
                     LDELLAQKFLLTDLRPPCSGDPAAHVVRRLAAIPTARAEERAIGSLLADTAAWDRHAGA
                     ASGDALRRLDRRAAALFVAEHAFQVDLALPLAGRSISRRVGEEVVRAAEILLRLTPQPH
                     GPAYLQDYRRKFEQRYGEHREVPLLELLDPDLGLGPPPPAEPPRFEKRQERLLAVALTA
                     LRERRRAVELDEASLTELATWTPRAGELPTSLDLFVSVAARSPAALDAGEFQVIVAPSV
                     GVAGAGRTLGRFADLLGPAGLAAIGEVYHAEDAVDPRVRAEVYYQPAKARFANVAVRPA
                     LRGHEIRFDGVAPGRAESVAIAPDELLVGVRDGRFYVRWPAIGGDIAGCAGHLLNQLQG
                     PTVARFLCEVSNDGRACMSAFDWGPARSFPFLPRVQSGRLVLRPAEWRVGAILDERWRG
                     SSAEALGVLREHWQLPRHVLDATGDNRLLVDLDDPAQAALLAGSLSEPGRRERLVLQEV
                     LPDLDQIWLPGPSGRYASEFVASLVAKDPVGKARAQAIPAADAGGQQARVRPPGSDWLF
                     AKLYGPACFQNDILTGHLAEFAEDLVNRGLAARWFFIRYADPEPHLRVRFHGTTDGLYP
                     AVCRWAASLVERGLCARLSFDTYDREVERYGGPAGVSLAEDIFAADSRTVVGLLALERA
                     RQLPVDLEKLALLTVDDLLAALGLDEPARLTWCRRALPFRDVGRDEYRRCQSQLRPLLD
                     RTMFAVSGGDASPALEVLRERSVALVPTARSLRSMVERGQLGRSRDDVLGCVVHMHLNR
                     LLGPDVRQEQRILALLLRTRESLAAYRG"
     aSDomain        complement(12338..12571)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_O0S08_RS10550_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="8.50E-16"
                     /identifier="RREFam001.1"
                     /label="O0S08_RS10550"
                     /locus_tag="O0S08_RS10550"
                     /protein_end="239"
                     /protein_start="161"
                     /score="49.4"
                     /tool="antismash"
                     /translation="GERVFLCDGGSLAPDTRRISIRASGPVRLALRLSRAPVPYCELVE
                     QIQRAHDAPRERIEQFLDELLAQKFLLTDLRPP"
     gene            complement(13126..14454)
                     /locus_tag="O0S08_RS10555"
                     /old_locus_tag="O0S08_10555"
     CDS             complement(13126..14454)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.5"
                     /locus_tag="O0S08_RS10555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_10555"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_308477871.1"
                     /sec_met_domain="LANC_like (E-value: 1.1e-41, bitscore:
                     142.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLLSATERPWPVFLDSARAATARALARDVAERLRRPEQVAEARA
                     RTRSQSDLPQHNQWMPCDLARGDVGLALFHGWMDACFPGESWDRVAHVHLTAAAQGTSA
                     LEFVPLGLHHGASGLAFCTQFLARGSRYQRMLASVESSLLPQIAAAAELCQRRRGRLHT
                     SDFDIISGLSGMVGYLLCRTDDQPAREALIAVARALVALVGADDVGPLWRTLPDFMDET
                     MRAHFPGGNLNCGLAHGGPGLLAALALTFRAGVRVDGSAAAIRALSEWLLASRVEDAWG
                     DSWPMAVPLLPGVPTTPCRNAWCYGSPGVARALWLAGEALEERTYCSAALEAMRAFCRR
                     PAPARGVDSPTLCHGLAGLLQIVMRFAHDSGSEDLHAEVQRLFDQLVACHAPGSLLGFQ
                     NVETGDVRTDHPGLLEGAAGVASVLLAAACAIEPTWDRAFLLS"
     gene            complement(14442..14648)
                     /locus_tag="O0S08_RS10560"
                     /old_locus_tag="O0S08_10560"
     CDS             complement(14442..14648)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS10560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_10560"
                     /product="hypothetical protein"
                     /protein_id="WP_269038954.1"
                     /transl_table=11
                     /translation="MRIFKNTRFDDEFDLDIRIKLPPPPDPNHEVHASGGCGSQPGNQS
                     CATPCGGTCTGCASNPPVSQCCC"
     CDS_motif       complement(14565..14648)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRIFKNTRFDDEFDLDIRIKLPPPPDPN"
                     /locus_tag="O0S08_RS10560_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(14442..14564)
                     /prepeptide="core"
                     /locus_tag="O0S08_RS10560_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="-1.50"
                     /molecular_weight="3653.0"
                     /monoisotopic_mass="3650.4"
                     /core_sequence="HEVHASGGCGSQPGNQSCATPCGGTCTGCASNPPVSQCCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRIFKNTRFDDEFDLDIRIKLPPPPDPN"
                     /leader_location="[14564:14648](-)"
     misc_feature    14608..14623
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.26"
                     /tool="antismash"
     gene            complement(14662..15414)
                     /locus_tag="O0S08_RS10565"
                     /old_locus_tag="O0S08_10565"
     CDS             complement(14662..15414)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS10565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_10565"
                     /product="hypothetical protein"
                     /protein_id="WP_269038955.1"
                     /transl_table=11
                     /translation="MGHGLDETVTAPLRSLSSQFSRSQMKRLRNAQMLDPVSLHVYKWL
                     VPITAPEVVFRYGRTEAEAHGTFRQIARMVEAVIHDDPRFTRLYDVLAEFASQPVSDLH
                     LVIANHWRLPGYTPVKSYLAVVYARALHVLRNGWFSLEESLPHVSSWLTGERVDLAIQH
                     LQARLEELGPRFFSQLVLETECRAAEDPDFEDRLDRAILAFEEHAGPAGRALWSGPSAE
                     QVSVLSSAEHRRGIGLFANIAFAFTLWD"
     misc_feature    complement(15367..15369)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(15752..15765)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.83"
                     /tool="antismash"
     misc_feature    complement(15799..15814)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 18.82"
                     /tool="antismash"
     gene            16031..16426
                     /locus_tag="O0S08_RS10570"
                     /old_locus_tag="O0S08_10570"
     CDS             16031..16426
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS10570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_10570"
                     /product="hypothetical protein"
                     /protein_id="WP_269038956.1"
                     /transl_table=11
                     /translation="MMRIDRAQQDQFAAEATSRFPERLRSFLSGRFREHAGALAGPAGL
                     ELVNGRIVEARTRGFVGERDIARYVTLGFVLGEGFVAEPWARAVFADSAIRTPTERIET
                     LWRTAEHRELDDAAGSTARAMSAPEKR"
     gene            16429..18402
                     /locus_tag="O0S08_RS10575"
                     /old_locus_tag="O0S08_10575"
     CDS             16429..18402
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS10575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_10575"
                     /product="hypothetical protein"
                     /protein_id="WP_269038957.1"
                     /transl_table=11
                     /translation="MSLEKWRRLHELEQAIREEFADTGCPTARCPAGPRVHLVFCHFGA
                     LVEPDRSLDSWRFATIDAYKAAAPKPREARVAADFLAAHFLWVRARDVRLDELPKLEQP
                     VAPAAADGGTLVHFQDASFDRTEVKAKVGAPARIDDFALVYRSSQGSSAGQGSGATAGA
                     VAGAGAAAGVASGAATGAGGAAAGAATGAAVGTCTGGAAAGAGTGAAAGAAGAAAGTGA
                     AGAAAGAAAGTGAAGAAAGAAAGTGAAGAVAGAAAGTGAAGAAGTGAAGEDATGIPRRR
                     RLCLSVPGSAGEHKDVDVAGATVEASLLYPVPTQHNELRLLSVSPGFQFEVGGTAVGAT
                     DPWTESTRAFTVAQRGQRLEERSSSTYVGKVVSSQWGVGIAKYASEGTDTTELANRHAC
                     DLGDSRVKVFKALRNVEGGCESVATYDGPKISWGINQWTLPSVTGELWQILAFIYDFYP
                     EAFARRFSYYGIGLWFASRAATWTAHGTYRDVLVYRLPCCGPQTRAAIDAVFAAGGAAA
                     GATAEAQAQTSDTPPAPMRGIAQALRLTRRATTSIAMCHVFTTAGADEDIQKAQAQWMS
                     YRISSTRPVGKTIGDVIDLFLRSLGSNMSATARLNTAVASLGDEYSPEQVQSLLGETFS
                     DDGASGGWIDWPTRCRDAGKST"
     gene            complement(18426..19556)
                     /locus_tag="O0S08_RS10580"
                     /old_locus_tag="O0S08_10580"
     CDS             complement(18426..19556)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024894.5"
                     /locus_tag="O0S08_RS10580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_10580"
                     /product="immunity protein Tsi6 family protein"
                     /protein_id="WP_269038958.1"
                     /transl_table=11
                     /translation="MRILSRDAFAEVLAEARRRTRALDPSRWPLLRQIEAQLEFIAEQT
                     KHGRVPHEDERLRTTLGPLAARNLEEVDPEYADQLEEIDYTFRRYPQLPSGPPVRRRGV
                     LQVWSGRETYRKLVLDLGVPRRVGSARADFVVHGDPAGSPHFQIIWDGVSAHVQAEGSH
                     RLSINGESAWYGEMANRGWMAAARTTYRFLVEDRTPPPEPITPSAAALEALAELERRCD
                     GGNLYAIIDAARSDRALQLVEESIDPYASLYDGEQGRAFDDIAPYLVHLQPSSWLLERL
                     VLEGWGDAWGIYAESGAGFDKVRHHFRKFLKVEVEGEPRPWFFRFYDPRVLRTFTKVMT
                     AEQRASFMQELDAILFESARTSASLEVWSAAARRGG"
     gene            complement(19579..20586)
                     /locus_tag="O0S08_RS10585"
                     /old_locus_tag="O0S08_10585"
     CDS             complement(19579..20586)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018690728.1"
                     /locus_tag="O0S08_RS10585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_10585"
                     /product="PAAR domain-containing protein"
                     /protein_id="WP_269038959.1"
                     /transl_table=11
                     /translation="MPDAARISDFHVCPKVEPGPVPHVGGPIFSGSANVIIGFLPAARE
                     GDSVVCFPLGAADRIKQGSSTVVINGRPAARRSDPGSHISGDLIAAGCPTVVIGDSTQA
                     FTFRSAAKRGVPLCEECERKRRQFDEKDDSAEPPAPDTATLDDETPPPGAELGRDLLSS
                     SLLNKQELAAQPNLNDGLDTERVAARIAVAYQFYAAHAGEKFKPSKLTSHIRAIDLSQP
                     VEVIAIAAQVLHQRGYPGGKNGEYFAFDPDLTPEQLGTSSIVPGPNGTRVPRDRRTVEF
                     GEAPAFALKSIAASVIDTWTFAETATDPGEQIPCEGGGMQVYVPRTFHVSSRNV"
     gene            20695..22557
                     /locus_tag="O0S08_RS10590"
                     /old_locus_tag="O0S08_10590"
     CDS             20695..22557
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS10590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_10590"
                     /product="hypothetical protein"
                     /protein_id="WP_269038960.1"
                     /transl_table=11
                     /translation="MDNQGGRVYGRQQPGVSTSFSPQIGERFAGRYELKSPLRADGALQ
                     AFLAFDHHAGLDVALLLFDSACAHPIAWSAFARIVGAATAAKIAGLVLPQGVAPTPPVP
                     PFCLAEPLALRGFDRLRDQGPMPWQRALTLGERATEILQAAHAATGVAHRVLTPSRCAV
                     TMRDDVRVLDFGVAELELGRPEGAGYRAPEQQQGGGDARSDVYTLAVILFELISGQKSA
                     GKPPPRLRSLVAVPRPVDEFMAKALSQDSAQRPDLGAMRASLRELLGVAAAPAEPTLPP
                     GPKPGASPVSIISAPPEASVVSPATAPERSKSAVGPGPAPTIEKASPARPPALSALSLS
                     SPSPPKPEVVSPRPRQAAAQSDGLPSLPELQESDGPGLMVHGLEDRTEKLDARRYPAPA
                     ADDRTEVLAAVSLRAPAVADRTEALAAASLPKREDPERTEMVRLDVPTVQDEETTAFRR
                     PLKGLLAALASSKASAADPVATPLAVTGDDAPTEKSVKLLSLADRTRLSSSEPPAATVA
                     SRPNAEVRPSPEPARPVDVTSRPAPEALSGSPEPAGLKSFEVQPAAEDRPAPGDQDEAT
                     TVFTPVQVPASPKPAVDPLKKALIWINVVCFAAFLLAMLWLLIA"
     misc_feature    complement(20715..20733)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 19.06"
                     /tool="antismash"
     misc_feature    20743..20757
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.01"
                     /tool="antismash"
     gene            complement(22629..23960)
                     /locus_tag="O0S08_RS10595"
                     /old_locus_tag="O0S08_10595"
     CDS             complement(22629..23960)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS10595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_10595"
                     /product="hypothetical protein"
                     /protein_id="WP_269038961.1"
                     /transl_table=11
                     /translation="MSDDGKHATAAGKAPALAAATREARQHPNADDPVATTSETCPVEL
                     TLIIQRIKEWPKNPQAQGTNARQGGTIAEFELLKVGDSTPLVTGVMLEAAGPSSLVAGS
                     DQRVLAGTYSLIKNPGTKGPYRLVQLSQDLADQSFGERSMVNIHSGNVPGDLEGCLCPG
                     PGWEERGVKKLNGVEDRSDVYPAVKAGSRDKLAELEREIRKYGRLETRTTYDGAETYTN
                     SSYYSNVRVIIRDIRPIYVYFAIFFVVGDRAFERAAATWERAVKASPEFLAGRDRFIPP
                     IAVSTETDFKTAWTQILTISKEPYHVIKEGRIFSHASKGDRQDGLEFEAGGGNDGTTNR
                     VELQSLQRLNWATDASLHLHSCNSGIVGGRGWSPAQVLAASQRVTVYGQTGYAYFSTNK
                     DRYVRIDDRSTDVYLWAYRRRLNAPLLVFGDDQSMPAANFPPPK"
ORIGIN
        1 ctccctccca cgaccgcgcc tcggagacgg gaattcccag ctcggccagg gcctccagcc
       61 cggcgtcgtc cagctcgctg agatcgaacg tgatcgactc tccggcgcgg gtggcgaccg
      121 cctgctgtgt ctcttcatcg aagtaaacga tccattcgtc gtgttcttcg ttcacttcgg
      181 cggaggagtc gctcacgcga ctcgtgtcgc cagacggcgg ggatacagcc aacaagagag
      241 caacaccata cttcaacatc tcgggggctc ctttcggcag caacagtagc ccgagatgat
      301 tcattgtcta gcgggcgtgc gggcgcgcgg gcgctaccga gctgaggtga tgtggattgg
      361 cacgacgtga ttgcagcgga gatgggtgcg gcctgcgagg gggccgaccg ttcgaaggcc
      421 tcgcgccttg aaggcgaggg gcacggtggt acgctccacg cgagacgccg gggggcgagc
      481 caccgctcgg gcggccggcg tgagggaagg ggcgcatggg cggcacgatc gtatctccgc
      541 ggatgttgtg cacattgtcg gcagtctccg ccgtcgcgtg tcctgtcaac acctccgacc
      601 tctccggcgg gcccgtctcg acgagcggca ccgacgaatc gatgggtcag accgagctgt
      661 ccgacgggcc cgccgacgac accacctcgc cgcccgccag cgatgaatcg caattggtgt
      721 acggcgacgc cccggccgcc ggctggagag tgaagatcga cggtgccgat gtcgacctgt
      781 tcagccggga ggaggtccac gccggaacag cggcgattgc ggtgacgttc acgggcgagt
      841 gggggagcgt gcgcttcgat gcgacgccgc ccctggcggc ggaggcctac accgcggtgg
      901 aattctggat ccatggcggc agcgccggcg gccaggagat cgagttcgcg gtcgtcgcca
      961 ggatcggcgt cgcggagctc tggggagcca gcaccgagcg gcgcatcacc gcccagccga
     1021 acgtctggcg cagggagagg gtcgagctct cgtcgctggg tagccccgtg aacgtgggca
     1081 tcctggcgtg gttgagcacg agcgggggtg aacagccgat cttctacctc gacgatgtga
     1141 cgctgatcgg ccgccctccg gaggacgcga gcgcgaccgc tggccacgcg ctcccgctgg
     1201 ggccgtgacg gcctccggcc cgatggtagg agtccccgcg acggcggtga ggcggcgcgg
     1261 cggccgggct ccgaccgcgg atccgcgcgc cgcgtgggac cggtcgcaag ccggccgcgc
     1321 gtcgcgcttg acgcgggtga aaggtccttt atcaccttcg aggcggggct cgacccgcct
     1381 ctcgcagtga ttcgaaggag caaacatgac cgatcgactc gacccgggtc agttcatcaa
     1441 gcgcaatacg cccgacgaca ggatcacgtc ggccaacggc aggtattcgc tcatcatgca
     1501 gaatgacgga aacctggtca tttataacca aggctcggcg atctgggcga ccaacacggc
     1561 cgggaccgac ggtgagacgg cggtcatgca gacagacggt aatttcgtcc tctatcgcgt
     1621 gaacggaacg cccctgtggg cgtcgaacac cgccggccgg cccgtctcct acgtcatcat
     1681 gcaggatgac gggaacctcg tggtctatca gaccctggcg acgtgggcca gcaatacggc
     1741 cggccaatag cccgtcgacg ccatcacggg cgcggcgcgc gtgcgccccg gccggcgctg
     1801 gacggctgca cgtggagggc cgtgcgcgtg acgaactcct gcaggcgagt cgcgcgatag
     1861 gcgtcgtccg ctcgcacgag cgccagcgcg ggggaggccg tggcgccgaa tcgcgtcttc
     1921 tcctggcggg cccccatgcc caggtgaagc cgctcgcagc cgagccgacc ggcgcggcgg
     1981 acgagctgcc acagtaattg tcgatagggg ttgatcttgc cggcggggaa ctcgtcgtag
     2041 tcgacgccgc aatagaggcc gcggtattcg cagccggcgg ggcgcgcggc ggcccacgcg
     2101 acgaccgggc ccccgcctcg ccgcctcagc agcaagaact cccacgagcc gctctcgagc
     2161 tgggcgcgca gcagctccgg cgggaggggg aagatgttga tccgcaggtt cttcgccgcc
     2221 atcctgcggt agagcgcgta caggcggcgg agctcgtcgt ccgccgcggc gctgcggctg
     2281 tcccagacct cgacgtcgaa caggggtgat tgctggtgga cggcgcggac gtgccgccgc
     2341 tggccgttgc tcgccagcgc gtcgatgaac gcgtcctcgc cgcgccagtc gagctgcacg
     2401 aggtagcgct cgatcagcgg cacggggacg aacccctggc cggtcaggac gcgcacgagc
     2461 tcgggatcgt cggcgagatc gcggaggacc agggtgctgc aattctgggc cttcatctcg
     2521 gcgacgccgg cctcggcgag ggcgatcagc gcggcgctgc ggccggcgcc gggggcgagg
     2581 aacatgtgct cgccctcgga cgccatgtcg cccatgacga cggcgcggga ggtgaacagg
     2641 tagggatcgg cgagccgctc gcgctcgagc gcggcgctga cggcggcgct catgaacgtg
     2701 tcgtctttca tcaggagggt ggtgaagggg gcggcggcga cgagctcgtc cccgcggcgg
     2761 acgagcacgt agcggaacga ccagcggtgc tcgcggagag cgtggccgcc gtgaaacacg
     2821 cgctccacgg cacgcatgga gcgggcgtcg atgtacgaga gatcgccgag gtgcgcgtcc
     2881 cagacccggg catcgagctg ttcgatgctc gcgtgggtct cgacggtgag cgcgtcggcc
     2941 ggctgcggat ggcgctcggg gagctgccgc acggcggagg cgagcgggcg cgcggcgcgg
     3001 aggaacggcg ggagcacgcc ctcgaactgc tcctcgacct cgtcgcgcgt gacgccgacg
     3061 gcggcgagca ccgccggcag gtgctcggcg atcgcccgga acagggcgtc gacctgcgcc
     3121 tcgctgtgga tggcgttgat ggcgatccgg atcccgccgc ggctggccgg cacggcgggg
     3181 aagccggaca cgttgacgtg aaagccgtgc tcccgcagcc gttcggccat caggtacacc
     3241 gcctcgacgc ggcccagggc gatgaagaag atcggggcct cgttctcgat gacgagcggg
     3301 atcccgagcg cccggcacag cgcgttggct cgatcgatcc gggcgcgcag cgccgcctga
     3361 agcaccgcca gctcggggct caggtggatc cgcgccgagg cgatgctcgc gccgagatcg
     3421 cccgggcgca gcggccccga gaacgagaag ggcccgccga cgaggcgagc ggtctcgagc
     3481 aagcggcggt cctgaacgac gatgacgccg ccgcccgtgg cgaacgcctt ggccagcgag
     3541 gtcaccagga cgacgcgctc gccgagcgga aagcgcgaca ggaaatgacc gcacccgcgg
     3601 tcaccggccc agctcatccc gtgggcgtcg tcgacgaaca gccgcacgtt cggcgcgacc
     3661 gccagcaggt cgtgcaggaa gccgagcggc agagaatcac cgtacatcga gtagacgccg
     3721 tcgcaggcga accacacgtg gtggtgcgtg cgcgcgagcc gggccacgat gtcgagcgcc
     3781 cggtcgagtt cgccgtgctt cacgaccacc ttgtcggcgc cgctgcgcgc gcattgcagg
     3841 gtgatcgcgt cgtcgaccga acggtggacc tggtggtcgc agacgatcgc gtcgttctcc
     3901 gccagcagcg ccggcatcac gacgtggtgg gcgatgctgg tgctcggcaa cagcagcacc
     3961 cgcggcacgc cgaagatccg cggcagcagg tcctcctcga gctccggata gagcggacag
     4021 gacaggtagc cgcggctgaa agacgtctgc gtgccgtagc ggcggtaggc ctcgaccccg
     4081 ccgtcgatga gccgcggatc gaactccagg cccaggtacg agcagctccc gaacgacagc
     4141 agtcgcttgc cggagacgcg gatatgtcgg tcgtcgaacc gctcgtcctc cgccgacagg
     4201 aaatagtgcc cgcggtctcg accgtggctg tgcacctgga atatcgcctc acgaaaactc
     4261 gacgcgtcca tcggatgtct ggtgatagca ggtccgtgcg cacgcgacag gccgctcgct
     4321 gctatccgcc gagagcgccg ctcggcgctc gcggggggcc attgcgcgat ctgcactcgg
     4381 gggagcgatc ggcgagctcg caccaggccg cgcgaggctt cagcgagcac cagacctttg
     4441 cgacaggtcg cgctccgggt cggcgccgcg acgtcgcgtg gaccgcggcc ccttttgatc
     4501 gatcttcagg ctcgacggac acggaaaccc tcccctcttc ctcatgccgg tggtactcct
     4561 cccggccatg gctctcgatc tcgcaccatc cttccaggcg ttgctggacg cgttccggtc
     4621 ggcaggaggc ccgctacaca cgacggggcc gctggccgcg gtgatcgact gcgacggtgg
     4681 cgcgcccggc atcgatgcgt gggccgacga cgtccggagc gcgggcggcg gtcacctcgt
     4741 cgagggggcc tctctgctcg cagggatccc gtggcacgtg cgcgctgcgc tggatctcga
     4801 gtggcaggac gagacgggac ggctcgacgg cacgacgctc gacatcgacg tctcccatcc
     4861 gtggcgcgcc ttcctccggc gcgcccggct cgcgcctccg ggcgcgctgg cgaacgaccc
     4921 attcgcgttc gtcctctcga tccaccccgt cactgggagc acggcccgat gcatcgcccg
     4981 ctggccgccc gcggcgacga ggccggagct cgtctaccac tcgggaggcg gcgagctcgt
     5041 cccgctgcgc ctctcggtcc gcgagtactt cgagcaggtc ctcgtcgcgc gcggctgggg
     5101 cggatgggag ctcgcgttcg ccgccgagcc gctccgagat ccggtgcagg tcgatgcgca
     5161 ggtgctcgct ccgctccgca gacggctcgg cgagcgattt ccggagctcg acctggccgc
     5221 gctcaaggct cgatagcccg gcgagttcat ggccattctc catattggcg aaacgaccaa
     5281 gcgcaagacg tgaaccagag ctcggcgacg atgcgctgga gcccgccgtc tctgctcgag
     5341 ccgcgcgacg cgaggtggcc cgcatggtgt tcgagcgact gatgacgatc ggcggggtgc
     5401 cgatcgtgcg acccgacgat tcagacgcat cgtcgtgcct gcggcgacaa tgatcatcgt
     5461 gcgtcgacag accgagcggg ccgccgagca gcacctgcgg cgcgcccggt cggccggccc
     5521 gaccttgacg gtgagcgacg acgacgagcg cgttcagagc gggacgagcc aggcgtcgac
     5581 gttgtgcaca gtcagcgcga gctcggcccc gggcgcgccg gcgaggtcgt ccgggacgtc
     5641 gatgtgcacc gcgacgagcg tgccggccgg gcccaggacc tcgagcggca gggcggtcgc
     5701 ctgcggcgtg tcgtcgccgc cggtctcgct gtcgccagtg gtcgtggtgt cgtcactggc
     5761 agtggtgtcg ccaccgccgg cagtgtcccc cgcgcacccg aacgcgacca gcaggagcgc
     5821 gagcgccacg tgagtcagtc gtgccacggc cgcagtgtat cagcggccgt gctgtcctca
     5881 atacggacat cacctcaggt agcgacggtg gcgacatcgt atctcctcgt cggaaacgct
     5941 cccctgtgat ttggggtatg cagaggacat ggcctgttcg cgtgcttcgc agcaggaatg
     6001 gatggtccgc agatgcgacg ctgcagcggt ttcacagggc ccgggcgcga gagcgaccac
     6061 cggtgggcgg cggccgctcg acgccgattg ctgcaggagc gggaggcccg ggctcacgag
     6121 gtgccagcag cagcgcatgc gtgacgcaga ggaccgccat gatcgccgcg agcgcgtcga
     6181 gccggtcgtg acccgaccgt gattcgcccg tcacgacgtc atgggctcgc tgcggtacgg
     6241 gagccgcggc tgtgcgaggc cttcctcgag tacgcgcagg cacgcggctt cgtgatcgac
     6301 gtcgcgcggg tgcgcaggcc gcaggacaag gcgcgagtcg agcgagcggt ccgcgacgtc
     6361 cgtgacgact gcttcggcgg tgaacggatc cgcgacctcg cggccgcacg ggagcgtgcc
     6421 gagcgatggt gccgggacga atacggcgtg caccgccaca gtaccaccgg tcggatgccg
     6481 cgcgagcact ttctcaatgt cgaggtgccg gtgctgctgc cggcgcccga gcagccctac
     6541 gacgtgccgc ggtggtgcac gccgaaggtc gcgcgcgatc acttcgtcca ggtcgagcgc
     6601 gcactgtact cgatgcccac gcggctgatc ggtcgcacgc tgcaggctcg agtcgatcga
     6661 agcagcgtcc gcttctacga tcggagcacg ctgatccgga tctgtcggcg gctgccgccc
     6721 ggcggccgca gcatcaaccc tgaggacttc ccgaaggaga aacgagccta cgcaatgcgt
     6781 gatatcgaat tcttgcagaa gcaggccgac gagctcggcc ccaacatcgg cgcgtacgta
     6841 cggcgactgc tgtccggccc gctgccttgg accagcatgc gcaccgtcca cggcgtgcgt
     6901 ggcctcgccg agcgccacgg cgtcgccgtc gtcgatcgct gctgcggcat cgcaatcgcg
     6961 gccgacatgc tgagcctgaa gcggctccgc gccatggtcg agcgcgacgt gaagccccaa
     7021 cccatccccc tcgaccggcc gacgccgccg gcgagattcc tccgacccgc gcagatctac
     7081 gcgctctcgg ccaacaccaa gcatggagaa ccgtcatgat cgataccatc tcacctgacc
     7141 tgaaggccat cctcaagcga ctcaaactca gccccctgct atcgacgctg cccgaccggc
     7201 tcgccctcgc acgccagcag aaggtcccgc accaggactt cctgctgacg ctgctcaccg
     7261 acgaggtcag ccgccgggac agcatctccg cccagctccg cggccagaaa gcgcgtctcg
     7321 atcccgagca ccagctcgag ggatgggaca gcaccactcg ggtccacttc gatcaagagc
     7381 tgtgggccga gctctgctcg ctgcgtttcg tcgaggctcg cgctcacgtc gcgctcgtcg
     7441 gccccgtcgg tgtcggcaag accttcctcg cgcacgccct gggcaacgcc gcctgccgcc
     7501 gtcaatacag tgtcctcgcc taccgctgtg atcgattgct caagaacctc cgccacgctc
     7561 gactcgacgg ctcctacgac gccgagctgc gcaagatcct cgccgtcgac gtgctgatcc
     7621 tcgacgactt cggcctcgac gcgatggacg cgaccgagag ccgcgacgcc tacgagatct
     7681 tcaccgagcg tcaccgccac ggctcgatca tcgtcacctc gaaccgtggc cctgacgaat
     7741 ggctcgcagt cttcgccgac cccgtccgcg cccaggcagc gatcgatcgc ttcaccagca
     7801 acgcctacga cctcgtcatc gaaggcgagt cgtaccgaag ccgccagaaa ccctcgctca
     7861 cccgtccgcc gaaaactgga tcccgctcgc gcacgcgagc atgatccccc tcgtcacgca
     7921 ggatggacca gagggggaaa ggtcgtgaga aggccggggt cccatgctgg tgaaaaccga
     7981 caaccggatc cacgggcctc gtgtatcctc ccgggatgca gtcgcgtcct tcgctctcgc
     8041 tcctcctctc gctcgccgtc gcgtcttgcg gaggcgaccc caaccaggat gacggagcga
     8101 cctcgaccgg tagcacgggc gagcccggca cgacgaccac cgacgcgagc gagccgaccg
     8161 gcagcaccac cgacgccccg accggcggca ccaccggcga cgcgcacgtc gtccccgagt
     8221 tcggcgggac cttcaccgtc atcggcaccg ccgacgacgg cctgcacgcg gtccgcgacc
     8281 tcgagttcaa cccggccgcc cccgagcagc tgtggacgtt caacatgctg agccacggcg
     8341 tcgtgatcta cttcgatcca ggcgcgccgc agcagacctc ggaggagcgg atcgacgcgt
     8401 acgggcagca cttcatggcg tacgtctcgt cggccgcgtt cggcgatctg gacacgttcg
     8461 cgacctgcca ggagtcgcgc aacgagtgga acgtcgggcc gcaagatccg gacgacttca
     8521 tgggcccggc gctgtggccg gccgacctgg acatcttcgc caaggtcggc caggagttcc
     8581 cgcccaacgg acaggagggc agccacctcg acatgctgca ccagagcccg ctgtgcatgg
     8641 gcatcgccca cgaggccggc aacgcgttct gggccttcga cggcatgcac ggcaacatcg
     8701 tccgctacga cttccaggcc gaccacgggc ccggcggcgg cgaccactcc gacggcatca
     8761 tcacgcgcta catcgacgtc acggtgaccc gcctcggcaa catccccggg cacatggagt
     8821 tcgaccacgc gaccgggatg ctgtacatcg tcgacaccgg cgccggacgg ctcctgcgcc
     8881 tcgacaccgc caccggcacg aacatcggca cgctccccgg cgactgggac ggggccgagt
     8941 acacgggcgt cgagggtgcc gacgtgcagg tcctcgtcga gggcctcgac gagccctcgg
     9001 gcctggcgct gcacgagggt cggctgttcg tgtccgagca cgggaccggc gacatcgtcg
     9061 cgttcgacct cgacggccag gagatcgatc gcatgaccac cccggccgat cgcatcatgg
     9121 ggatcacgat cggcccggcg ggcgacctgt ggtacgccga cgccggcgcc gacgagatcg
     9181 tccgcgtcga cgagtgagcg gcctggcgac gcgcgccgcg gtgggcgtcg acgtcgtgcc
     9241 gcgagcgccg cgggcggcgg aggtccatgc ttgatgagca tgtcgagctt cgacgcctgg
     9301 cgggcccgac tcccgcggct cacggggacg cgggcgatcg tgcggatcgc cgcgttgcgc
     9361 ccgcgcgacg ccgactacgt cgtcctcgag gtcgaccccg gcgcggtctc gggctcgctc
     9421 cttcggctgt tcgcgccgga gacgtgcttg ctcgcggcgg ccgctgccgg cccgaacctg
     9481 gggcgcgagc tcgccgatcg cctcggcggc gacgcgacct cgcaggccct gtgccggctc
     9541 ctcgcggggc cgtttcctcc cgagcgcccg ctctgtccct cgacgaccgg tggcgcgagc
     9601 ggctccgtcc gctggcgctc ggccgcccgg gtgaccgggt cgaccacggg ctgtttccct
     9661 ctcgcgcgac caagctggcg cggctgctgc tcgccgccgc cggggactac ccggccgacg
     9721 aggtgctcct cgcagcgcgt ggagcctacg cccacgggcg cccctatcac gctcacgacg
     9781 cgctcgcgtg cgcgctggta tgcgcggggg cgccggcccg cgcgctgctg cgtgagcgct
     9841 tgcgagacac ccgggcggtc cggggctggc gctcgcggcg gcagacccat acgctggggc
     9901 gatgggcgcg ggcttttgga tatatgtccg aagagccagg ttgacgtcgc ggccgcccgg
     9961 cctgaactcc aggccgaccg acgcggctca tgcgctgact ttatccgcgg tatgcggcga
    10021 gagactcgcg tgtccgcagg agcagcgcca ggatgcgctg ctcctggcga acatcgggcc
    10081 caagcagtcg attgaggtgc atgtggacca cgcacccaag gacgtcgtcg cggcttcgtc
    10141 cgagctgccc tcgctcgacc atgctccgca acgaccgcgc ggtcgggacg agcgccacgc
    10201 tccgctccct caggacctcc agggccgggc tcgcgtcgcc gccggagacg gcgaacatcg
    10261 tgcggtcgag gagcggacga agttgcgact ggcagcgccg gtactcgtcc cggccgacat
    10321 cgcggaacgg gagcgctcga cggcaccagg tcagccgggc cggctcgtcg aggccgaggg
    10381 ctgcgagcag atcgtcgacc gtgaggagcg ccagcttctc cagatcgacc ggcagctgcc
    10441 tggcccgctc gagcgcgagc agacccacca cggtccggct gtcggccgca aaaatgtcct
    10501 ctgccagcga cacgccggcc ggaccgccgt atcgttcgac ctcgcggtcg taggtgtcga
    10561 acgagagacg agcgcacaac ccccgctcga ccaggctcgc ggcccagcga cacaccgccg
    10621 ggtacagccc gtcggtagta ccgtggaacc gtacccgcag atgtggctcg ggatcggcgt
    10681 agcggatgaa gaaccacctg gccgccagcc ctcggttcac caggtcctcg gcaaactcgg
    10741 ccaggtgccc cgtcaaaata tcattctgaa agcaggcagg cccgtacagc tttgcaaaca
    10801 gccaatcgct cccgggcggc cggacccggg cctgctgacc gccggcatca gccgcgggga
    10861 tcgcttgggc tcgagccttc ccgacggggt ccttcgccac cagcgatgcg acgaactcgc
    10921 tcgcgtagcg tccgcttggc cccggcagcc agatctggtc caggtcgggc aacacctctt
    10981 gcagcacgag gcgctccctg cggcccggct cgctcagcga gcccgcgagc aaggcggcct
    11041 gcgcagggtc gtcgaggtcg acgaggaggc ggttgtcgcc ggtcgcgtcc aacacatggc
    11101 gaggcaattg ccagtgctcg cggagcacac ccagcgcctc cgcgctgctc ccgcgccagc
    11161 gctcgtcgag gatggcgccg acgcgccact ctgcaggtcg cagcaccagc ctgcccgact
    11221 ggactcgcgg taggaagggg aagctgcgcg cgggccccca gtcgaacgcg ctcatgcacg
    11281 ctcgtccgtc gttgctgact tcacagagga aacgcgccac agtcggtccc tgcagctggt
    11341 tcagcaggtg cccggcgcag ccggcgatgt caccgccgat cgccggccac cggacgtaga
    11401 agcggccgtc tctcacgcct acgagcagct cgtccggcgc aatggcgacg ctctccgccc
    11461 gcccgggagc cacaccgtcg aatcgtatct cgtggccgcg gagcgccgga cggacggcga
    11521 cattggcgaa tcgagccttc gcgggctgat agtacacctc ggcccggacg cgcgggtcga
    11581 ccgcgtcctc ggcgtggtac acctcgccga tcgcggcgag ccccgcgggc ccgagtagat
    11641 ccgcgaatcg gccgagcgta cggccggccc ccgcgacccc gacgctcgga gcgacgatca
    11701 cctgaaactc gccggcatcc agcgcagctg gcgaacgagc ggccaccgag acgaacagat
    11761 cgagagaggt cggtagctcg cccgctctcg gagtccaggt ggcgagctcc gtcagcgacg
    11821 cttcgtcgag ttcgaccgcg cgtcggcgct cgcgcagggc ggtgagcgcc acggcgagga
    11881 gccgctcctg gcgcttctcg aagcgcggcg gctccgccgg tggaggcggt ccgagcccga
    11941 ggtccggatc gagcagctcg aggagcggga cctcgcggtg ttcgccgtag cgctgctcga
    12001 actttcgccg atagtcctgc aaatacgccg gaccgtgggg ttgcggggtc aaacgcagca
    12061 agatctcggc cgcccgcacg acctcctcgc cgacccgacg cgagatcgac cgccctgcga
    12121 gcggcaacgc caggtcgacc tggaacgcgt gctcggcgac gaacaatgct gcggcccgcc
    12181 ggtccaaccg cctcaacgca tcgccggacg cggcgccggc gtgtcgatcc caggccgctg
    12241 tatcggcgag cagcgacccg atcgctcgct cttccgccct cgccgtgggg atcgcggcga
    12301 gccggcggac gacatgcgcc gcggggtctc cggagcatgg agggcgaagg tcggtgagca
    12361 agaacttctg cgccaagagc tcgtccagga attgctcgat gcgctcgcgg ggcgcgtcgt
    12421 gagcgcgctg gatctgctcc acgagctcgc agtagggcac cggcgcccgg gacaggcgga
    12481 gcgcgagccg gacgggtccg gacgcccgga tggagatgcg gcgggtgtcc ggagcgagcg
    12541 agccgccatc gcagagaaat actcgttcgc ctgcgaacca tgccagtgga ttcgccgtga
    12601 cccgcaaata cgcgaggacc tctcgccgac gctcgagccg atccacgacc ccgtatagcc
    12661 actccatgtc cgggcgggtg cgaaggatcg gtggggaatc gcccagcgcg aggtcggtcc
    12721 gctcacccca acgcgccagc gcgacccccg aaaacaggcc gtagggcgtc ggccgggtgg
    12781 acatgcggat caggtacgcg aggagcttct gtcgcgccgc tctccccttc cgcggcgcca
    12841 ggacatcgct ggcgagcgcc gcatggagct tcggcgaggc gatcgccagc gcgtctcgta
    12901 cccagtcacg atccgcgacc atcgtcctgc gcccgggggg actcgcccac tgggcagcac
    12961 gatccagcga atcgggcgga cccgccggcg aacccgcgag ggcttgatag tcctcgatcg
    13021 aacagacagg ggtccgtacg aggacgaacg gcaagagtcg gtagaaagag cccgtcgctg
    13081 ggtcagcgga ttcggccttg tcttgagtca tacaatggag cgagctcagc tcaggagaaa
    13141 cgcccggtcc caggtcggtt cgatcgcgca ggccgcggcg agcagcaccg aggcgacgcc
    13201 cgccgcgccc tcgagcagcc cgggatgatc ggtgcgaacg tcacctgtct cgacgttctg
    13261 gaagccgagc aagctcccgg gcgcgtggca ggcgaccagc tgatcgaaga gccgctggac
    13321 ttccgcgtgg agatcctcgc tcccgctgtc gtgagcgaat cgcatgacga tctgcagcag
    13381 ccctgcgagg ccgtgacaaa gagtcggcga atcgacgccg cgcgccggcg ccggacggcg
    13441 gcagaaggcc ctcatcgcct cgagcgccgc cgagcagtac gtgcgctcct ccagggcctc
    13501 gcccgccagc cagagcgctc gtgcgacgcc ggggctgccg tagcaccacg cattacgaca
    13561 gggcgtcgtc ggcacgcccg ggagcagcgg gacggccatc ggccagctgt cgccccaggc
    13621 gtcttcgacg cggcttgcca ggagccactc cgagagcgct cggatcgccg ctgccgaccc
    13681 gtcgacacgg acgccagcgc gaaacgtcag ggccagggcg gccagcaagc caggcccccc
    13741 gtgtgccagg ccgcaattga ggtttcctcc cgggaagtgc gcccgcatgg tctcgtccat
    13801 gaaatcgggc agggtgcgcc acagcggccc gacatcatcc gccccgacga gcgcgaccaa
    13861 tgctcgcgcc acggcgatca aggcctcgcg cgccggttgg tcgtccgtgc ggcagagcag
    13921 gtagcccacc ataccactca ggccggagat gatatcgaag tcgctggtat ggagccggcc
    13981 gcggcgccgc tggcagagct ccgcggcggc ggcgatctgc ggcagcagcg acgactccac
    14041 ggacgcgagc atgcgctgat aacggctgcc gcgcgccaga aattgggtgc agaaggcgag
    14101 gccggaggct ccatgatgga ggccgagcgg cacgaactcg agagcgctcg tcccctgagc
    14161 ggcggcggtg agatggacgt gcgcgacccg atcccaggac tctcccggga agcacgcgtc
    14221 catccagccg tggaacagcg cgaggccgac atcaccccga gccaggtcgc acggcatcca
    14281 ctgattgtgc tgcggcaggt cgctctgcga tcgggtcctg gctcgagctt ccgcgacctg
    14341 ctcgggtcgc cgcaggcgct cggcgacgtc ccgcgccagc gcccgcgccg tcgcggcgcg
    14401 ggcgctgtcg aggaagaccg gccatggccg ctcagtcgcg ctcaacagca gcattgcgag
    14461 acgggggggt tgctcgcgca gccggtgcag gtccctccgc aaggggtggc gcagctctgg
    14521 ttccccggct ggctcccgca gccgccgctc gcgtggacct catggttcgg gtcgggcggg
    14581 gggggcagct tgatccggat gtcgaggtcg aattcgtcgt cgaatctggt gttcttgaag
    14641 attctcatgg cttcctccgg ctcaatccca cagcgtgaag gcaaaggcga tgttggcgaa
    14701 gaggccgatt cctcgccggt gttcggccga ggacaggacg ctcacctgct ccgccgaggg
    14761 gccggaccac agcgccctgc cggccggccc ggcgtgctcc tcgaacgcca ggatggcgcg
    14821 gtcgagccga tcctcgaagt cagggtcctc cgcggcgcgg cactcggtct ccagcaccaa
    14881 ctgactgaag aatcgcggtc ccagctcctc gagcctggcc tggaggtgct ggatcgccag
    14941 gtcgacccgc tccccggtca gccagctgga gacgtgcggg aggctctctt cgagcgagaa
    15001 ccagccgttg cgcaggacgt ggagcgcgcg cgcgtagacg acggcgaggt agctcttgac
    15061 gggcgtgtag cccggcaggc gccagtgatt ggcgatgacc aggtggaggt cggagacggg
    15121 ttggctcgcg aactcggcga ggacatcgta gagcctggtg aagcgcgggt cgtcgtggat
    15181 gacggcctcg accatccggg cgatctgccg gaacgtcccg tgcgcctctg cctcggttcg
    15241 gccgtagcga aacaccacct cgggggcggt gatcggaacg agccatttat agacgtgcag
    15301 gctcaccggg tccagcatct gagcgttgcg aaggcgcttc atctggctgc ggctgaactg
    15361 cgacgataag ctccgcaagg gggccgtcac cgtctcatcc agaccgtggc ccatgatcga
    15421 tttactctgt ctttcgtgca tcgtgctccc tcccgggccg tccgtcggac tgcctctacc
    15481 gaccctcgac cccccatgtc ggataatact gatgcttaaa tcccaaacgc gtgtcaagcc
    15541 acgccgccaa ttcgcaccgg acgttgttta tcctcgcggc cgaggccttg gcccgacaga
    15601 gcggcgtcct acgcattccc cggatgcggc tcgggggggt aacggcccac acgcttatga
    15661 gcgatggacg ctgtgcgaga gtgcgcatga atcgagcatg tcggctcgat cggggcgcga
    15721 ggggcaggcc gccgaggagc gccatttcgg cttaccatga tcatactcgc cggataaacg
    15781 cgagcgagca acccatctgg ttccatgtgt attcgcagct ctcgccgctc agcggggagg
    15841 gagcgtccgc gggaccgatc cgagcagcga gagattggcg cgaagaggcg catcgtctcg
    15901 ccgagcccta cgcgcgcgga gcaccggcgt cggggcacga tatcgcacgg tcgtgagtat
    15961 tgactcgcgc tctccgaccc gcatatgctg agcttcggcc tggttcctgg tcggagatgg
    16021 taatgtgtcc atgatgagga tagacagggc gcagcaagac cagttcgcgg cggaggcgac
    16081 gagccggttt ccggagcgac tccggtcatt cctctctggc aggttccgcg agcacgcagg
    16141 cgcgctcgcg gggcccgcgg ggctcgagct cgtcaatggg cggatcgtcg aggcgcggac
    16201 gcgcgggttc gtcggggagc gagacattgc ccggtatgtg acgctggggt tcgtcctcgg
    16261 tgaggggttt gtggcggagc cgtgggcgag ggcggtattc gccgattcgg cgatccgcac
    16321 accgaccgag cggatcgaga cgttgtggcg gacggccgag catcgcgagc tcgacgacgc
    16381 cgccggatcg acggcgcggg ccatgagcgc ccccgagaag aggtagcgat gtcgctcgag
    16441 aaatggaggc gattgcacga gctcgagcag gcgatccgcg aggaattcgc ggacacgggc
    16501 tgtccgacgg cgaggtgtcc ggcgggtccg cgcgtgcacc tggtcttctg ccatttcggg
    16561 gccctcgtgg agccggacag gtcgctcgat tcctggcgat tcgctaccat cgatgcatac
    16621 aaggcggcag cgccgaagcc gcgcgaggcg agggtcgccg cggacttcct cgcggcgcac
    16681 ttcctgtggg tgcgggcgcg agacgttcgg ctggacgagc tcccgaagct cgagcaaccg
    16741 gtcgcgcccg ccgcggccga cggcggtact ctcgtgcatt tccaggacgc cagcttcgat
    16801 cgaacagagg tcaaggcgaa ggtgggggca cccgcgagga tcgatgactt cgcgcttgtc
    16861 tatcgctcct cgcagggttc gagcgccggg caggggagtg gggcgactgc cggggccgtg
    16921 gcaggggccg gggcggcggc aggagtggcc tcgggagcgg cgacaggcgc ggggggagct
    16981 gcggcagggg cggcgaccgg agctgcggtt gggacatgca ccgggggcgc tgcggcaggc
    17041 gcggggacgg gcgcggcggc aggggcggca ggagcggcgg ccgggacggg cgcggcggga
    17101 gcggcggcag gagcggcggc cgggacgggc gcggcgggag cggcggcagg ggcggcggcc
    17161 gggacgggcg cggcgggtgc ggtggcagga gcggcggccg ggacgggcgc ggcaggggcg
    17221 gcggggacgg gcgcggcagg ggaggacgcg accggcattc cccggcgcag gcggctctgc
    17281 ctgtccgtgc cgggcagcgc gggcgaacac aaggacgtgg acgtcgccgg ggcgacggtc
    17341 gaggcttcgc ttctgtaccc cgttcccacg caacacaacg agctccgcct gttgagcgta
    17401 tcgcccggtt tccagttcga ggtcggcgga acggccgtcg gcgcgaccga tccgtggacg
    17461 gaatcgacgc gcgcgttcac ggtcgcgcaa cggggccagc ggctcgagga gaggagctcg
    17521 tcgacctacg tcgggaaggt cgtgtcctcg cagtggggag tcggcatagc gaagtacgcg
    17581 agcgagggga ccgacacgac cgagctcgcc aatcgccacg cctgcgacct cggcgattcg
    17641 cgggtcaagg tcttcaaggc cttgagaaac gtcgagggcg ggtgcgagag cgtggcgaca
    17701 tacgacggcc ccaagatctc ctggggcatc aatcaatgga ctttgccgtc ggtgacgggc
    17761 gagctctggc agatcctggc gttcatctac gatttctacc ccgaggcgtt cgcccggcgc
    17821 ttcagctact acggcatcgg tctctggttc gccagccgcg ctgccacgtg gaccgcgcac
    17881 ggaacgtacc gcgatgtcct cgtgtatcgc ctgccctgtt gcggtccgca gacccgcgcg
    17941 gcgatcgacg cggtgttcgc cgcaggcggg gcggcggctg gtgcgactgc ggaggcgcag
    18001 gcgcagacga gcgacactcc gcccgcgccg atgaggggca tcgcccaggc gctccggctc
    18061 acccgtcgcg cgacgaccag catcgccatg tgccatgtgt tcacgaccgc cggcgcggat
    18121 gaggacatcc agaaggcgca ggcgcagtgg atgagctacc ggatctcgtc gacgaggccg
    18181 gtcggcaaga cgatcggcga cgtgatcgat ctctttctga ggagtctcgg ctcgaacatg
    18241 agcgcgaccg cccgcctaaa cacggcagtc gcgtccctgg gagacgagta ttcgccggag
    18301 caggtccaat cgctgctggg ggagacgttc tccgacgacg gcgcgagcgg cggttggatc
    18361 gactggccga cgcgctgtcg agacgccgga aagtcgacct aggccccgac gaggcccttg
    18421 cgtcctcacc cgccccggcg ggcggcggcc gaccagacct ccaaggacgc gctcgtacgt
    18481 gcggactcga agaggatggc atccaactct tgcatgaaac tcgcgcgctg ctcggccgtc
    18541 atcaccttcg tgaaggttcg aaggacccgc gggtcgtaga agcggaagaa ccatggcctc
    18601 ggctcgccct cgacctcgac cttgaggaat ttgcggaagt ggtgccgcac cttgtcgaag
    18661 ccggcgccgc tctccgcgta aatgccccag gcgtcgcccc aaccttcgag gacgaggcgc
    18721 tccagcagcc acgagctcgg ctgcaggtgc acgaggtagg gggcgatgtc atcgaaggcg
    18781 cggccctgtt cgccgtcgta gagggaggcg taggggtcga tgctctcctc gacgagctgg
    18841 agggcgcggt cggagcgggc ggcatcgatg atggcgtaga ggttgccgcc atcgcagcgg
    18901 cgctcgagct cggcgagggc ttcgagggcg gcggcggagg gggtgatggg ctcgggcggc
    18961 ggggtgcggt cctcgacgag gaagcggtag gtcgtgcggg cggcggccat ccagccgcgg
    19021 ttggccatct cgccgtacca ggcagactca ccgttgatag agaggcggtg cgagccttcg
    19081 gcctggacgt gggcgctgac gccgtcccag atgatctgaa agtgcgggga accggcgggg
    19141 tctccgtgga cgacgaagtc ggcgcgagcg ctgccgactc tgcgcgggac gccgaggtcg
    19201 aggaccagtt ttcggtaggt ctcgcgccct gaccatacct gcaagacccc ccggcggcgc
    19261 accggcgggc cggagggcaa ttgcgggtag cggcgaaatg tgtagtcgat ctcctcgagc
    19321 tgatcggcgt actcggggtc gacctcttcg aggttgcgag ctgcgagcgg gccgagggtg
    19381 gtgcgcaggc gctcgtcctc gtgaggcacg cggccgtgct tggtctgctc ggcgatgaat
    19441 tcgagctggg cctcgatctg ccgcagcagc ggccagcggg aggggtcgag cgcccgggtg
    19501 cgtcggcggg cctcggcgag cacctcggcg aaggcgtcgc gcgacagaat ccgcatcagg
    19561 tcggccatgg tgtacgcctc agacgttgcg gctggagacg tggaaggtcc gcgggacgta
    19621 cacctgcatg ccgccgccct cgcacgggat ctgctcgccg ggatcggtgg cggtctcagc
    19681 gaaggtccag gtgtcgatca cggaggcggc gatgctcttg agggcgaacg cgggggcctc
    19741 gccgaactcg acggtgcgcc tgtctcttgg gacacgtgta ccgttcggcc cggggacgat
    19801 cgaggaggtg ccgagctgtt cgggcgtcag atccgggtcg aacgcgaagt attcgccgtt
    19861 tttgccgcca ggatagccgc gctggtggag gacctgagcg gcgatggcga tcacctcgac
    19921 gggctgcgac aggtcgatcg cgcggatatg agaggtcagc ttgctcggct tgaatttctc
    19981 gccggcgtgg gcggcgtaga actgataggc gacggcgatt ctggcggcga cccgctccgt
    20041 gtcgagaccg tcgttcaggt tgggctgggc ggcgagttcc tgcttgttga gcagtgagct
    20101 cgagagcagg tcccgaccga gctcggcgcc gggcgggggc gtctcgtcgt cgagggttgc
    20161 agtgtcggga gcgggtggct ctgccgagtc gtctttctcg tcgaactgac ggcgcttgcg
    20221 ctcgcactcc tcgcacagcg gaacacctcg tttggcggca gagcggaagg tgaaggcctg
    20281 ggtggagtcg ccgatcacga ccgtcgggca gccggcggcg atcaggtcgc cggagatgtg
    20341 agagcccgga tcggacctgc gggcggcggg tcggccgttg atcaccacgg tcgaagagcc
    20401 ctgcttgatc cggtcggccg cgccgagcgg gaagcagacc acgctgtcgc cctcgcgagc
    20461 ggcgggcaag aagccgatga tcacattggc gctgccgctg aaaatcggac cgccgacgtg
    20521 cgggacgggg cccggctcga cctttgggca cacatggaag tcgctgatcc gagcggcgtc
    20581 gggcataaac gccgccatcc tatcacatgc cggatccatt gggtcgggtc gaggtcgcgc
    20641 ggcgcggagg cgaacatgtg cggcgccagg gcccacgagg tattcgggcg gtcgatggac
    20701 aaccagggcg gccgcgtata tggtcgacaa caacccggtg tgtcgacctc gttttctccc
    20761 caaataggcg agcggttcgc cggccgctac gagctcaaat cgccgctgcg ggccgacggc
    20821 gcgctgcagg cattcctggc gttcgaccac catgcgggcc tcgatgtcgc gctgctgttg
    20881 ttcgattcgg cttgcgctca cccgatcgcg tggagcgcgt tcgcgcggat cgtcggggca
    20941 gcgacggccg ccaaaatcgc gggcctggtg ctgccgcagg gggtcgctcc cacgccgcct
    21001 gtgccgccgt tctgcctggc cgagccgctg gcgctccgcg gattcgaccg attgcgcgat
    21061 caagggccga tgccgtggca gcgcgccttg actctcggcg agcgggcgac ggagatcctg
    21121 caagcggcgc acgcagcgac gggcgtcgcg caccgcgttc tgacgccgtc gcgctgcgca
    21181 gtgacgatgc gcgacgatgt cagggtgctc gacttcggag tggcggagct ggagctggga
    21241 cgcccggagg gggcaggcta tcgggcgccg gagcagcagc agggcggcgg cgatgcacgc
    21301 agcgacgtgt acacgctcgc ggtgatcctg ttcgagctga tctcgggcca gaagtcggcc
    21361 ggaaagcctc ctccgcgcct ccgctcgctc gtcgcggtac cgcggccggt cgacgaattc
    21421 atggcgaagg cgctgtcgca ggattcagcg cagaggcccg atctcggggc gatgcgcgcg
    21481 tcgcttcggg aactgctggg tgtcgccgcg gcaccggccg agccgacgct tccgcccgga
    21541 cccaaacccg gggccagccc ggtctcaatc atctcggcgc cgccggaggc gagcgtggtg
    21601 tcgccggcga cggcgccgga gagatcgaaa tccgcggtcg ggccagggcc ggctccgaca
    21661 atcgagaagg cttcgccggc acggccacct gctctctccg cgctgtcact gtcatctccg
    21721 tcgccgccca aaccggaggt cgtttcgccg cggccccgtc aagcagctgc gcagtcggat
    21781 ggcctgccga gcctgccgga gcttcaagag tccgatgggc cgggtttgat ggttcatggc
    21841 ctggaggaca ggacggagaa gctggatgcg cggcgctatc cggcacctgc ggccgacgac
    21901 aggacggagg tcctcgcagc cgtctcgctc cgggctccgg cggtcgccga caggacggag
    21961 gccctcgccg ccgcctccct tccgaagcgg gaagatcccg agcggaccga gatggtgagg
    22021 ctggacgtcc caactgttca agatgaggag acgacggcgt tcagaagacc cctcaagggt
    22081 ttgctcgcgg cgcttgcgtc atccaaggcg agtgccgcgg acccggttgc cacgccgctc
    22141 gcggtcacgg gcgacgatgc accgacagag aagagcgtca aactgctgtc cctggccgac
    22201 aggacgcggc tgtcgtcgtc cgaaccaccg gcggcgacgg ttgcgtctcg gccgaatgcg
    22261 gaggttcggc cgtcgcccga gccggcgcgt ccggtggacg tcacgtctcg gccggctccg
    22321 gaggccctgt cggggtctcc cgaaccggcg ggcctgaaat cgttcgaggt tcagcctgcc
    22381 gcggaggatc ggcccgcacc cggcgatcag gacgaggcga cgacggtgtt cacgccggtc
    22441 caggtgccgg cgagcccgaa gccggcggtg gatccgctga agaaggcgtt gatctggatc
    22501 aacgtcgtgt gcttcgcggc gtttctgctc gcaatgctgt ggctgctgat cgcctgagtt
    22561 cgcggccggc gtcagcctcc gacgaagacg tcgcgcggcg gtcgtccgcc atgtgccgag
    22621 acatcgcttc atttcggcgg aggaaagttc gccgccggca tgctctgatc atccccgaac
    22681 acgaggagcg gcgcattgag tcgcctgcga tacgcccaca agtagacgtc ggtggagcgg
    22741 tcgtcgattc tcacgtatct gtccttgttg gtcgagaagt aggcgtaccc cgtctggccg
    22801 tacacggtca ctcgctgcga ggcggcgagc acctgcgccg gtgaccaccc gcgcccgccg
    22861 acgatccccg aattgcagct gtgcaggtga aggctggcat ccgtcgccca gttgaggcgc
    22921 tgcaggctct gcaactcgac gcggttcgtg gtgccgtcgt tcccgccgcc ggcttcgaac
    22981 tccaggccgt cctggcggtc gcccttggaa gcgtggctga agatccggcc ttccttgatg
    23041 acgtgatagg gctccttgct tatcgtcaaa atctgggtcc acgcggtctt gaagtccgtc
    23101 tcggtcgaga cggcgatcgg cgggatgaat cggtcccgcc ccgcgaggaa ttccggcgat
    23161 gccttgacgg cgcgctccca cgtcgcggcg gcgcgctcga acgcacggtc gcctaccacg
    23221 aagaatatgg cgaagtagac atagatcggg cgaatatctc gaatgatgac ccggacattt
    23281 gaatagtaag agctgtttgt gtatgtctcg gcgccgtcgt aggtcgtccg agtctcgagc
    23341 cgtccatact tgcggatctc ccgttcgagc tcggcgagtt tgtccctgct gccagccttg
    23401 acggccgggt acacgtcgct gcgatcctcg acgccgttca gtttcttgac tcctcgctcc
    23461 tcccatccgg gacccgggca cagacatcct tcaagatccc ccggaacgtt tcccgagtgg
    23521 atgttgacca tggagcgctc accgaagctc tggtcggcca gatcctggct gagctgtacg
    23581 agccggtacg ggccttttgt ccctggattc ttgataaggg agtaggtgcc cgccagcacc
    23641 cgctgatcac tgccagccac cagactggac ggacctgcgg cttcgagcat gacaccggtg
    23701 acgagtggcg tggaatcgcc gaccttgagt agttcgaact ccgcgatcgt gccgccctgc
    23761 cttgcattcg tcccttgcgc ctgggggttc ttcggccact ccttgatccg ctgaatgatg
    23821 agggtgagct cgaccggaca cgtctccgag gtcgtagcga cgggatcgtc ggcgttcggg
    23881 tgctggcgcg cctctcgcgt cgcagcggcg agtgcggggg ccttgcccgc agccgtcgcg
    23941 tgtttgccgt cgtcgctcat ggcgcagctc caccgggttc cgcctcgagc gcccgcaaga
    24001 aagccaccgc aggctgacag aggggatcgt cgacgaagcg ggggccgaac agccacccga
    24061 gcagcaagtg acggtcgctg gctcgcccgc gcagcctcag tcgttccccg tcgatgcgag
    24121 cgagctcgag gaagcgagcg aattgcggag tgcccatgaa cccggctcgc gccggcgtca
    24181 acgttcggag cacgcgctcg agcgcgtcgg gctggactgc caggcgctgt tcgccggcga
    24241 tcacggcctc ctcgaagcct gccagcgaat cttcgctgaa gaacccggaa ccgacggccg
    24301 cttccaggtt ctcggcgaac gtgccaatat tgcagtggag cgctccgtcg acgtcgtccg
    24361 agtcgagccg cccgtgaaac agccacgcgc agcgtggatc gtcgaacacg aacaggccgc
    24421 acacgcacgc gcacgcgagg tagatcagga gctc
//
