LOCUS       NZ_CP114040            20987 bp    DNA     circular CON 26-AUG-2024
DEFINITION  Nannocystis poenicansa strain FL3 chromosome, complete genome.
ACCESSION   NZ_CP114040
VERSION     NZ_CP114040.1
KEYWORDS    RefSeq.
SOURCE      Nannocystis poenicansa
  ORGANISM  Nannocystis poenicansa
            Bacteria; Myxococcota; Polyangia; Nannocystales; Nannocystaceae;
            Nannocystis.
REFERENCE   1  (bases 1 to 13228663)
  AUTHORS   Ahearne,A., Stevens,C. and Dowd,S.
  TITLE     Minimal conservation of predation-associated metabolite biosynthetic
            gene clusters underscores biosynthetic potential of Myxococcota
            including descriptions for ten novel species: Archangium lansinium
            sp. nov., Myxococcus landrumus sp. nov., Nannocystis bai
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 13228663)
  AUTHORS   Ahearne,A., Stevens,C. and Dowd,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-NOV-2022) Biomolecular Sciences, University of
            Mississippi, Faser Hall 407, Oxford, MS 38655, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2021
            Assembly Method                   :: IPA v. 10.1.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 250x
            Sequencing Technology             :: PacBio Sequel IIe
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_026965555.1-RS_2024_08_26
            Annotation Date                   :: 08/26/2024 12:45:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,229
            CDSs (total)                      :: 10,129
            Genes (coding)                    :: 10,068
            CDSs (with protein)               :: 10,068
            Genes (RNA)                       :: 100
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 9 of 61
            Pseudo Genes (incomplete)         :: 52 of 61
            Pseudo Genes (internal stop)      :: 2 of 61
            Pseudo Genes (multiple problems)  :: 2 of 61
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:28:22
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2051531
            Orig. end                         :: 2072518
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP114040.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20987
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20987
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20987
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10987](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10987
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    149..164
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 20.92"
                     /tool="antismash"
     misc_feature    303..318
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.27"
                     /tool="antismash"
     gene            932..1132
                     /locus_tag="O0S08_RS07935"
                     /old_locus_tag="O0S08_07935"
     CDS             932..1132
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS07935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_07935"
                     /product="hypothetical protein"
                     /protein_id="WP_269038422.1"
                     /transl_table=11
                     /translation="MSPVVVSVVVGVAVVDPVGSTVSPLEVDEDDEVDEVEVSVTVSLA
                     GLSPHPAVMRPVQAIALDIRE"
     misc_feature    1070..1072
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(1539..2219)
                     /locus_tag="O0S08_RS07940"
                     /old_locus_tag="O0S08_07940"
     CDS             complement(1539..2219)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS07940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_07940"
                     /product="hypothetical protein"
                     /protein_id="WP_269038423.1"
                     /transl_table=11
                     /translation="MANPLPRSFALAETRRRYEATPRGLDDDLQRMARGDRGCLGDAVA
                     GVGALGILVSGVLGYLGFLGMGFMAVFAGLLIAGFVLSAAAQTRSGPARLKALTEGPLA
                     LGRVLRADPALFEPGDVPYPALVVFAVDAPHRFDAPYLQGVAAALLALRDAATAPADQA
                     EVAAMLRDPNRVAPLPVPPALAGAGEAWLGVVSVDPRRLPARRVEDHLVPVIAAPGLGF
                     VEHV"
     gene            complement(2504..4306)
                     /locus_tag="O0S08_RS07945"
                     /old_locus_tag="O0S08_07945"
     CDS             complement(2504..4306)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS07945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_07945"
                     /product="hypothetical protein"
                     /protein_id="WP_269038424.1"
                     /transl_table=11
                     /translation="MADDRKSNSARDSRPRAAGPGPAGGPQQDRPRRERGRGPREGGES
                     AGGGAAGAEARPPREGGAEARPPRDGERGERRDGPRGDRPRQGDGPRGDRRDDRRGAPP
                     PRRDTSSPLTASLFSAVQDKEMPCRIAGCENTWTWFAAQQIRGFGQKPPERMCDQHLAQ
                     FSELSDREVHCRTPGCPNTWLWKRGAQLAELQRHGRLKKPARLCNECVAAERDTHDAEM
                     PCKVEGCRRGWVWSRDAQLRHRLWVLRQRARARAVEARAHEAVAAEAGPPAVEAAPSDL
                     SAETAVEAGAPVLEAMSPATDEAAAPGEAHEHGEAGKAGPGKKRRRRRKQHARAVPDPE
                     GPPQRMCGLCAQKLGRLAAREIPCKVHGCVRTWTWDRAGQLRAWVQSGSDDVDFDPPAP
                     KRMCETCREFCRKHPDREIHCGRPGCESVWMYKTGAQLQAFLAGRLQDPLKLCDECAKG
                     EFAKTIEEAGLPEGAEIMPCVVPACDGTWVYMPGQKLMHVPDGELAPDRMCLKCKRERG
                     LAAPEEVAAEPAAELEISPEDTEAPDDDGEELLADDPEPPADVDGAPDDGAHADDDGAH
                     ADDDEALAGDEPTEGDEAQVATSD"
     gene            4409..4642
                     /locus_tag="O0S08_RS07950"
                     /old_locus_tag="O0S08_07950"
     CDS             4409..4642
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS07950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_07950"
                     /product="hypothetical protein"
                     /protein_id="WP_269038425.1"
                     /transl_table=11
                     /translation="MLLALLIGCGTAGATYAYSKQRQATNGAAAGAAALTGVSSAAVAY
                     AALVFWPLVLLGGVGYLWMRGSGPKALGPGRS"
     gene            5058..6749
                     /locus_tag="O0S08_RS07955"
                     /old_locus_tag="O0S08_07955"
     CDS             5058..6749
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021597.5"
                     /locus_tag="O0S08_RS07955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_07955"
                     /product="DUF2330 domain-containing protein"
                     /protein_id="WP_269041944.1"
                     /transl_table=11
                     /translation="MCAGLVAGLAAWLPATQAHACGGFFCDLVNNQPTPVDQTGENILF
                     AIDEAAGTVEAHIQIQYTGDPLKFGWVIPVSAEPDFAVGSELLFTNLLAATVPTYSFTT
                     ARDCSDDDDRSLGCVAIALDGGFAGSGGVETDGSTEDSGGFEVVKREIVGPFEIVVLKG
                     GSADEVWQWLDAAGYYQDPAAGPIMQEYLDEGFYFAAAKLLHGAGVEELQPIVMTYEGT
                     TPCVPLRLTAIAAMPDMPVRVFGLGHSRYAPSTYRHVELNDVAIDWTTNASNYTEVVAR
                     ALDAPMADGHGFVTEYAGGSNVVSREGIFSDRWDAETFVEAAPINAGVSVIDALALQGL
                     VDCSFNPCSYNHPQLLPLLRTYLPAPPGIPEDLFYSDMAAYEDMIDLDAWSGPAFANAL
                     RERIIDPGRRAVDLLARWPYLSRLLTILSPEEMTVDPEFIQNPDLGDVSNLRQGVMQLP
                     CAGSNRMRMPNGRGVLLDEFGNWPTFKDMPAAQRVEQIAPAGAPQVLQDFDAAIVASLK
                     ASNARFDYDDGDGVSCALRRGSWSAALGLGVVFVFAWRGRRRRPAA"
     gene            complement(6876..7550)
                     /locus_tag="O0S08_RS07960"
                     /old_locus_tag="O0S08_07960"
     CDS             complement(6876..7550)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS07960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_07960"
                     /product="hypothetical protein"
                     /protein_id="WP_269038426.1"
                     /transl_table=11
                     /translation="MRPRRSFLRLAAGALALTAGRARAQAPVVDRQLARRLELWAKAAA
                     GTRVLVARYALTRQSTLLQEPLKTAGTLLARAPDTLVLRDDTRAGVTTRLSRGRLEIRP
                     NDPALPALAEAPSPTVTWLFEHVLALFSVPEGAGEPAAALQLDARLTVPRGPGHLLAIT
                     PRRDHPARREIRDLVVHLDPHTGDVDQLDLVEAGGDKVVITFSQRRRDAPEDEITALLQ
                     PT"
     gene            complement(7680..9869)
                     /locus_tag="O0S08_RS07965"
                     /old_locus_tag="O0S08_07965"
     CDS             complement(7680..9869)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS07965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_07965"
                     /product="hypothetical protein"
                     /protein_id="WP_269038427.1"
                     /transl_table=11
                     /translation="MPPRPTLTALAWLAVCAALGLVAGARGTEAQVWGLIPAAHRPVIE
                     IDLRVHLDDGAPDEALEAAIAALEPLAGRCPLAPPPAEARRWLDAHALSLLPREHHSAL
                     ADRLAPEALRTAIAGARARLASPFAGLVGDDLRRDPLRLAELAPQRSASLGFLAAAGPE
                     PTVRGDLVSPDGRSALLCFHTGAPVHELRASAAALVAGHPVSLAVVGAPARDEAAAAAL
                     AAAPRVLTTLAAALTLVLALAFRSVRPVVALLLAILGPAALLAALVAPLGLLDLPLLAL
                     AVGISAAPARPDWTITALSALALTPLLLTPYPAWQTWGLAWAAGLAAAGLARRLVQPAL
                     AAWLGKPAAERAPFGRPDPPPLRLRAALPAAAACAVVLSLGAWSSRHVRFDSPSPLPLA
                     DPELAAAEAAVRAEFFRPEEVATIHSPGATPEEALSRAAELLPSLLALVPTQIDRLDAP
                     GAFVVAEPELKARVDGLLALDIRGRLELLRATIAEFGMRPDAFGEFIRGAGDDLRDPPS
                     PESALAGPLGPWLTAKFGPDGVLTRVYLAGEQAALPAALDLRGPGVFARAEHDRFSARA
                     GAVAAAGAWLSALVVWLATRRLALALALALAAIVAQCGLLVLLHLLHRSFGPLTLPVFL
                     LAGSAAVVAGLRAVQALAAGRPWIDPGRLANALGPLAAALALLAAPEPVWRSLGIAAGL
                     AVLAAHGVGGLVGPLLYSLTSRAADRFVRRPTRDA"
     gene            10001..10987
                     /locus_tag="O0S08_RS07970"
                     /old_locus_tag="O0S08_07970"
     CDS             10001..10987
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.4"
                     /locus_tag="O0S08_RS07970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_07970"
                     /product="hypothetical protein"
                     /protein_id="WP_269038428.1"
                     /sec_met_domain="T1TS (E-value: 3.1e-65, bitscore: 220.4,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSLLQPSIFEPQAAPINRYAELVEREGIAWVLRFFPSVALSPGR
                     LRKLQAAKFARLAARGLPRAPLAELRLVCDWITWLFFYDDALCDDVVAAPEPLKRLHEA
                     QVRMSAVLRGSPALEDDEPLVHMLAELGARTAAWAAPGFMPRFVAEVERYFQSNVWELR
                     NLLHQLRPALPIYLKMRPFTGAAGVVFALIELIRHESLGEVRQHVVVQQLELLANNAIC
                     WANDIGSLEKEMVEQNPHNLVLVLQADQGITLDEALARAVAMQGAEEDAFDALAASLRD
                     YDGLSSPAVLGYVADLGSFVRGNFVWMQETMRYRARLSMRSYGSAAA"
     gene            11547..13004
                     /locus_tag="O0S08_RS07975"
                     /old_locus_tag="O0S08_07975"
     CDS             11547..13004
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.5"
                     /locus_tag="O0S08_RS07975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_07975"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_269038429.1"
                     /transl_table=11
                     /translation="MLWGVPYTGSPALAARVMLTNQVFVVCLAVILAYICLFVALGLYT
                     EALTVIPFWLSYLACMFANKFGWFNVSRIGLCICCCTAIVFFASMLGEPSGLQFIMFPI
                     IGFPLVCFEARERTQIVFCMAVVVISFFVGELSDYSLAPRSAVTSAAQHWIYLLMILTT
                     FTLTLGPTLLFFLASHRAEGRLIHSNTELQRVNDQLNRARDEAIRANQAKSFFLANMSH
                     ELRTPLNAIIGYAELLRDELEDEGVRAASVDLEKIRGAGKYLLNIINDVLDLSKIEAGR
                     IDMFWETFALDDLVDDVAGMIRPQAEARRNRLELVRPPAGLGAVTVDKTRLRQALVNLL
                     HNACKFTEAGVVKLAVAREPGRQGDAIDEWVVFKISDSGIGMSPEIVRELFQPFSRGDL
                     ESSRKYEGTGLGLAISRRLVRMMGGDITVESTPGMGSTFTVRIPAHATLANSSGSGSQT
                     ATGSQVAVVSSSYSASASSSFSWIGGS"
     gene            13127..14002
                     /locus_tag="O0S08_RS07980"
                     /old_locus_tag="O0S08_07980"
     CDS             13127..14002
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS07980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_07980"
                     /product="hypothetical protein"
                     /protein_id="WP_269038430.1"
                     /transl_table=11
                     /translation="MKTAPSKRGPTSNKYALELHGKPCGWLTDVSGALAVGELGGEGRP
                     DRYEELTLRCWPGMPHEFYAWVAASMTSRPTPARGEVILADDGNAEMSRLSFVGGVITE
                     LALASYEYGFRDSLKLNLKFSPHSSKRSYAGGHLGGEVIEARRPLPATDPELHIDGLEE
                     ACSQVRRIEGLTIRQRIERPPGDDGIYTVRRVAPAVVGRLALVLAENKALGFTRWLEAV
                     EAGRSNGRAATLTLGAPAVGFTVVLQQVRPARIVEEPGEVGDSRRRELRVELDARGVEF
                     AFAPVREAVV"
     gene            14013..16343
                     /locus_tag="O0S08_RS07985"
                     /old_locus_tag="O0S08_07985"
     CDS             14013..16343
                     /EC_number="3.6.4.-"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024754.5"
                     /locus_tag="O0S08_RS07985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_07985"
                     /product="ATP-dependent helicase"
                     /protein_id="WP_269038431.1"
                     /transl_table=11
                     /translation="MQLNPAQQAAVEHRGSPLLVLAGAGTGKTRVITHRVAALMDEGVP
                     PWRILAVTFTNKAAAEMRARIEKMCEGKVDVSQLWVGTFHSISARILRRHGESVGLSRN
                     FAIYDTDDQTRLMKRVFKELNRDEDQVKPRAILGHLDQLKNRGLTIDQVDQLGLEGFMT
                     RLTALLGRRYQELLRAADAADFGDLLVLAVKLLEKAGTEQPRPGAQLVDVDPVIGLKRR
                     FLHVVVDEYQDTNPVQARLVELLSGRAQLCVVGDDDQAIYGWRGADVSQILGFPDRQPG
                     CELIRLEQNYRSTGHILRCADAIIRRNEGRLGKTLWSELGDGALVTLRACEDEREEARF
                     VVNEILDALNEDIPPDEIAVFYRTHAQSRVIEQQLTDNGMRYAIFGGLGFFERKEIKDA
                     LAYLRLLQNPNSDLDFTRIVNEPARGIGDTTVGRLTTLAANRNVSLLTVARSPEEAGVS
                     GAAAKRLHVFVAMIDELTARLHAKVPLGQLAAEVLERTGYRDALVHEGSEESEARVENL
                     DEFVGALNDFAQDNPDQTLADYLEQVSLVSDADGGGHGEVRAVRLMTIHSAKGLEFEKV
                     ILTGMEEKVFPHSRVIAGEEAAREEGRRLRPEERAQIEEERRLAYVAVTRAKRQLVVTW
                     AKRRRLYNQEFIGTPSRFVRDLPPDSVRGRVPGVVRREAVGVPAGLSLPSAPPRAPAPA
                     RESSWNSDIVYDEGVAAAPTRRGPAAVQGDAPTLYKGMAVRHRQYGEGTLVGWDGTGSN
                     LKLAINFPVVGVKTILARFCEPL"
     gene            16377..16946
                     /locus_tag="O0S08_RS07990"
                     /old_locus_tag="O0S08_07990"
     CDS             16377..16946
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS07990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_07990"
                     /product="hypothetical protein"
                     /protein_id="WP_269038432.1"
                     /transl_table=11
                     /translation="MLRAIVVVVLAAVAATPACKGSESALPAGEVGGGEPSRVPLVPKD
                     HALYARFEGTAFENACSDDAACSKGGCSSEVCASGDQPPGTCDVPEVQIPAAANCGCVA
                     GECVWWSDGSLTLAAAAEKPTPAEQAGPRCGDVTCAAGETCIEYYGIAGPRGPKFQTCG
                     IPCPHGKCADGKKCITIADGPGPVCQ"
     misc_feature    complement(17024..17039)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.08"
                     /tool="antismash"
     gene            17220..18194
                     /locus_tag="O0S08_RS07995"
                     /old_locus_tag="O0S08_07995"
     CDS             17220..18194
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF026220.5"
                     /locus_tag="O0S08_RS07995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_07995"
                     /product="YCF48-related protein"
                     /protein_id="WP_269038433.1"
                     /transl_table=11
                     /translation="MKLRSLTPLLVVLMAPIVGCTKDDNKNTSTSDGSGGGAWAVGEDA
                     TMVRLNPAGDVWYYPLEIEGDLLAIACKGQETGMAVGEDGVVLRTDDSGESWTQIDVGT
                     RARLRSVIFSGTTPAYIAGDGIVLRSDDDGRSFTPVPDAEGDFTAVTTTAKGTLAWLTT
                     ASGQIWQLDGETLTPVFTTSEGPLSGIAATPDGGSVVAVGAGGLVLRSDDGGAKWASVT
                     TPTSRDLHAVRISRTADLVVAVGAAGVVLRLDDELGASAEELLEPGLALRALHLSIDGH
                     GHAVGDHGVVVHSNDAGLAWEALDLGLEEALFGLDDLHGEAHL"
     gene            complement(18798..19160)
                     /locus_tag="O0S08_RS08000"
                     /old_locus_tag="O0S08_08000"
     CDS             complement(18798..19160)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS08000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_08000"
                     /product="hypothetical protein"
                     /protein_id="WP_269038434.1"
                     /transl_table=11
                     /translation="MTSLRNTLENSMQELRTLRDEIRVRLNLAGKEARDRWEQQMEPRI
                     EKLEQQIRTATDATLESIRDAIERARTSFHEYRAQLTQGSAGGVTGSEGGEERREQTRA
                     ESGDEPDFTRVEPEKR"
     gene            19260..20951
                     /locus_tag="O0S08_RS08005"
                     /old_locus_tag="O0S08_08005"
     CDS             19260..20951
                     /EC_number="3.5.-.-"
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019397599.1"
                     /locus_tag="O0S08_RS08005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_08005"
                     /product="amidohydrolase"
                     /protein_id="WP_269038435.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 2.5e-06, bitscore:
                     26.2, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRARGLTRRTWLAGASALIACRPGGGKTAATCPPDQAGGLLVVRN
                     GTIWTGDPAEPNTRAIAAVGGRVIARGAAAESLARDCPRGQVLDLAGGSAVPGLTDAHA
                     HLVGLGSALVEVDLRGARSVEEVVDRVRRGAPPDGWITGRGWDQNLWPGAAMPTHDPLT
                     TAFPERPVWLRRVDGHAGWANAAALRAGDITAATEVPTGGEILLREGPSGREPTGVLVD
                     AAMDLMPVLPPPGPELRRRLLLAQDYALARGLVGVHEMGVGRHVDALLRELAAEGLLKL
                     RLVGYADESWFRRGDGLPDLADRPAMDDRYALQGVKIYVDGALGSRGAALLQPYSDRPG
                     HTGMFQHAPGELAAVVTRALAHQYQVAAHAIGDAAIRAVLEALAGARPPADHRLRVEHA
                     QIVDLADIPRFAELGAIASMQPTHATSDMPWAEQRIGAQRLAGAYAWRRFLDAKVTLAF
                     GSDFPVEEVEPTFGLYSAITRQDAAGNPPGGWLPDQRLTLAEALAAFTRGAAYASRRER
                     WAGTLAAGMLADVTCFEGDITKMQPLELRTAKVRATIVGGEVVAPK"
ORIGIN
        1 gaacggcgtg ccgaactgga cgccgttgtt gttctggttc cacaccacga ggccgtcgtg
       61 atcgaggatc atcgccccga gcgcgacctc ggcctcggga tcgtcgtcga ggttggccac
      121 ggtcaccgag gcgttgtcga cccggacctt ggcgatctgg tcgttcgcca gccgcgccgt
      181 ccacagcagc tggccctggc cgtcgaccgc gtggatcggc gcgagctgca tgactccctc
      241 gggccgcccg gcgtagatga tgtcggggac gccgtcgccg ctcacgtcgc cgacggcgag
      301 ggtcgagcgc ccgtgcgagc cgaactgcat gttgcccggg tcgtgggcga tccgccactt
      361 ctcctccccc gtcgcgccgt cgaggaggac gatctcgcct accggccagg tccccgtccc
      421 cgccgtggcc gagacgacga catcgggcac gccgtcgtcg tcgacatcgg cgatgatcgg
      481 cgtcgtcgcc acctgatcgg tcgtccactc ccacgcgagg gcgacgtcga gcggaccggg
      541 ttcgcagccg agcgagtccg gcagcggcag gcactgaccg agcagcgggt cgcaggattg
      601 cccggcctcg cactcgctgg agtcctggca ggggccgagc gggagctggc acgcgtcgcc
      661 gaggcagacc tcgccggcgg cgcagcagat cgagtcgtcg gggccgcagt ggacgccgcc
      721 ttcgcacgcg gggacgcagg cgccgctcag gcactcctcg cccgcagcgc agcagccggc
      781 cggtagaccg cagagcagcg cgcacgactc ggcgccgccg ctggtcgtcg agtcggtggt
      841 cgtcgaggtc tcggtcgtcg actcggtggt cgtcgaggtc tcggtcgtcg agtcggtggt
      901 cgtcgaggtc tcggtcgtcg agccggtggt catgtcgccg gtcgtggtgt cggtggtcgt
      961 cggcgtggcc gtggtcgatc cggtcggctc cacggtttcg ccgctcgagg tcgacgagga
     1021 cgacgaggtc gacgaggtcg aagtgtcggt gactgtctca ttggcagggt tatcgccgca
     1081 tcccgccgtc atgaggccgg tgcaggcgat cgcgctcgat atcagggaat agcgagaaag
     1141 gaagctcatg ccagtagtaa gccacaggcg cctgcgactg tcgcgttcga tcgcctgacc
     1201 gtgcgcggga gggcagtttg gaaccgtcgg cgctgcctgt gttcgagccc tggtgcttcg
     1261 cccgatcggc tcgtgccccg tgatccacgc gcgtcgagag ggcgggctcg tgggcgctcg
     1321 tgtcgagttg gacggcgagg gcgcgtggag gcggccgcgg gaagtgctcg catcggcgcg
     1381 caccgacgca tcgagcacgt gccgtctcat ccctggcgcc gcgagtcgta cggggtcgac
     1441 ggggccgaac cctggtgtcg tctcgacgac tcgcgcagcg gctcacacgt cgtcgaagga
     1501 gccgaacctc gcgtcgtctc gtcgacgcgc gccgcggctc acacgtgttc gacgaagccg
     1561 agccccggcg ctgcgatcac cggcaccaga tgatcctcga cgcggcgcgc gggcagccga
     1621 cgcgggtcca cgctgacgac gcccagccag gcctcgcccg cgcccgcgag cgcggggggc
     1681 acgggcaggg gcgccacgcg gttggggtcg cgcagcatcg cggccacctc ggcctgatcg
     1741 gcgggcgcgg tcgcggcgtc gcgcagggcc agcagcgccg cggcgacccc ctgcaggtac
     1801 ggtgcgtcga agcggtgcgg cgcgtcgacg gcgaacacca ccagggcggg gtagggcacg
     1861 tcgccgggct cgaacagggc cgggtcggct cgcagcacgc ggccgagcgc cagcggcccc
     1921 tcggtcagcg ccttgaggcg ggccgggccg ctgcgggtct gggcggccgc gctgagcacg
     1981 aagccggcga tcagcaggcc cgcgaacacg gccatgaagc ccatgccgag gaagcccagg
     2041 tagccgagca cgcccgacac caggatcccc agcgcgccga cgccggcgac cgcgtcgccg
     2101 aggcagccgc ggtcgccgcg ggccatccgc tgcaggtcgt cgtcgaggcc ccgcggggtg
     2161 gcctcgtagc ggcgccgggt ctcggccagg gcgaaggaac gcgggagcgg gttggccatg
     2221 gccgaaagga cctgtctcga agtgcctgtg cggagggacc tggtcgagag gacctgtgcg
     2281 ttcggccctg gtccgaacga caggtgcccc gcgacgatcg cggggcgggc gagggaccgg
     2341 acctgggcgc gaggctcgag gtcaggtcgg agagggcgcg cacgcgggag cggtcggagt
     2401 cgctgggacg agcgtcgggc gcggggcccg ggagcgtgag gacgcggtcg agagagcagc
     2461 gtcgcgtgcg cccgcggagg ctcgcacgcg acgctgcggc ccgtcaatcc gaagtcgcga
     2521 cctgggcctc gtcgccctcg gtcggctcgt cgcccgcgag cgcctcgtcg tcgtcggcgt
     2581 gcgcgccgtc gtcgtcggcg tgcgcgccgt cgtcgggcgc gccgtcgacg tcggccggcg
     2641 gctcggggtc gtcggccagg agctcttcgc cgtcgtcgtc gggcgcctcg gtgtcctccg
     2701 gcgagatctc gagctcggcg gcgggctcgg cggcgacctc ctcgggggcg gcgaggccgc
     2761 gctcacgctt gcatttgagg cacatgcggt cgggcgcgag ctcgccgtcg ggcacgtgca
     2821 tcagcttctg gccgggcatg tagacccagg tgccgtcgca ggccgggacc acgcagggca
     2881 tgatctccgc gccctcgggc aggccggcct cctcgatcgt cttggcgaac tcgcccttgg
     2941 cgcactcgtc gcacagcttg agcgggtcct gcagccgacc ggccaggaag gcctgcagct
     3001 gggcgccggt cttgtacatc cacaccgact cgcagccggg ccggccgcag tggatctcgc
     3061 ggtcggggtg cttgcggcag aactcgcggc aggtctcgca catgcgcttg ggcgccggcg
     3121 ggtcgaagtc gacgtcgtcg ctgcccgact gcacccacgc ccgcagctga ccggcgcggt
     3181 cccacgtcca cgtgcgcacg cagccgtgca ccttgcacgg gatctcgcgc gcggccaggc
     3241 gcccgagctt ctgcgcgcac aggccacaca tgcgctgcgg cgggccctcc gggtccggca
     3301 cggcccgcgc gtgctgcttg cgccgacgcc ggcgcttctt gcccggcccg gccttgccgg
     3361 cctcgccgtg ctcgtgcgcc tcgccgggcg ccgcggcctc gtctgtcgcc ggggacatgg
     3421 cctcgaggac aggcgcgccg gcctcgacgg ctgtctcggc ggacaggtcc gaaggggcag
     3481 cttcgaccgc cggcggccca gcctcggccg cgaccgcctc gtgcgcgcgg gcctcgacgg
     3541 cgcgggcgcg ggcccgctga cgcaggaccc acaggcggtg gcgcagctgg gcgtcgcgcg
     3601 accagaccca cccgcgccgg cagccctcga ccttgcacgg catctcggcg tcgtgggtgt
     3661 cgcgctcggc ggccacgcac tcgttgcaca ggcgggccgg cttcttcagc cggccgtggc
     3721 gctgcagctc ggcgagctgg gccccgcgct tccacagcca ggtgttgggg cagccggggg
     3781 tgcggcagtg gacctcgcgg tcactgagct cgctgaactg cgccaggtgc tggtcgcaca
     3841 tgcgctcggg cggcttctgg ccgaagccgc ggatctgctg ggcggcgaac caggtccagg
     3901 tgttctcgca gccggcgatc cggcacggca tctccttgtc ctggacggcg ctgaacagcg
     3961 aggcggtcag cggcgacgag gtgtcgcgcc gcggcggcgg ggcgccgcgt cggtcgtcgc
     4021 gacgatcgcc gcgcgggccg tcgccctggc gcggacgatc gccgcgcggg ccgtcgcgcc
     4081 gctcgccacg ctcgccgtcg cgcggcgggc gagcctcggc tccaccctcg cgcggcgggc
     4141 gagcctcggc tccagccgcg ccgccacccg ccgactcgcc gccctcgcgc ggacctctgc
     4201 cgcgctctcg cctggggcgg tcctgctgcg gtccgcccgc ggggcccggg cccgcggccc
     4261 tcggccgcga atcgcgggcg ctgttgctct tccggtcgtc tgccacggcc ggaagtatca
     4321 gccgccgtcc gcccggcgtc cagtccgctc gccccgcccc tcgaaagcac tatactgcga
     4381 cacaccgctt tttccggagg tcccgctcat gctcctcgcg ctactcatcg gctgcggcac
     4441 cgccggcgcc acctacgcct acagcaagca gcgacaggcg accaacggcg ccgcggcagg
     4501 cgccgccgcg ctgaccggcg tgagctcggc cgccgtggcc tacgcagcgc tcgtattctg
     4561 gccgctcgtg ctgctcggtg gggtcggcta cctgtggatg cgcggctccg gcccgaaggc
     4621 gctcggcccc ggtcgcagct gaggcgctgc agagcgcgag aagacgctgt cccgctccgc
     4681 ggcgcgcacc tcggcgagca tggccggccc ggtcgaaggc cgcgagctcg gtgcgcgcga
     4741 gcagggcgcg ccgtgagctc ggtccgcgag gcgggaggcc gtgagctccg cggcagcgcg
     4801 cgggcgtcgg cgacgtgagc tccatcctgc gagagcggtg ttcagcgccg ctccgggcgc
     4861 ttcgagatct ccgcgcgcgg cgagaacggc gtcccgccgc cgcaatcggc ggtgcgccgg
     4921 agcggagccc gaagcggggg tcgccgatgg atcgcaggac gggcggcgcc tcgcctgggg
     4981 atctgcgtcc ccctggacgc cgcgccgggg atcgcgtgtc atcaggtccg atgtggcgtg
     5041 gctttcgtcc cttgttcgtg tgcgccgggc tggtcgcagg tctcgcagca tggttgccgg
     5101 cgacccaggc acacgcgtgc ggcggcttct tctgcgacct ggtcaacaac cagccgaccc
     5161 ccgtcgacca gaccggcgag aacatcctgt tcgccatcga cgaagccgcg ggcacggtcg
     5221 aggcgcacat ccagatccag tacaccggag atccactgaa gttcgggtgg gtcatccccg
     5281 tgagcgcgga gccggacttc gccgtcggct ccgagctgct gttcaccaac ctgctggcgg
     5341 cgaccgtgcc gacctacagc ttcaccaccg cgcgcgactg ctcggacgac gacgaccggt
     5401 cgctcggctg cgtcgcgatc gccctcgacg gcggcttcgc cggcagcggc ggcgtcgaga
     5461 ccgacggcag caccgaggac tccggcggct tcgaggtcgt caagcgcgag atcgtcgggc
     5521 cgttcgagat cgtggtgctc aagggcggct cggccgacga ggtgtggcag tggctcgacg
     5581 cggccggcta ctaccaggat cccgccgccg ggccgatcat gcaggagtac ctcgacgagg
     5641 ggttctactt cgcggcggcg aagttgctcc acggggccgg ggtcgaggag ctgcagccga
     5701 tcgtgatgac ctacgagggc acgaccccgt gcgtgccgct gcggttgacg gcgatcgcgg
     5761 cgatgcccga catgcccgtg cgcgtgttcg gcctcggcca cagccgctac gcgccgtcga
     5821 cgtaccgcca cgtcgagctc aacgacgtgg cgatcgactg gaccacgaac gccagcaact
     5881 acaccgaggt ggtggcgcgg gcgctcgacg ccccgatggc cgacggccac ggcttcgtca
     5941 ccgagtacgc cggcgggtcg aacgtggtca gcagagaggg catcttcagc gaccgctggg
     6001 acgcggagac cttcgtcgag gcggcgccga tcaacgccgg cgtgtcggtg atcgacgcgt
     6061 tggcgctcca gggcctggtc gactgctcgt tcaacccttg ctcgtacaac cacccgcagc
     6121 tgctgccgct gctgcgcacg tacctgccgg cgccgccggg gatccccgaa gacctgtttt
     6181 attccgacat ggcggcctac gaggacatga tcgacctcga cgcgtggagc gggccggcgt
     6241 tcgccaacgc cctgcgcgag cggatcatcg accccggccg ccgcgcggtc gacctgctgg
     6301 cccgctggcc gtacctgtcg cgcctgctga cgatcctctc gcccgaggag atgaccgtcg
     6361 acccggagtt catccagaac cccgacctcg gcgacgtctc gaacctccgc cagggggtca
     6421 tgcagctccc ctgcgccggc tcgaaccgca tgcgcatgcc caacggccgc ggcgtgctgc
     6481 tcgacgagtt cggcaactgg ccgactttta aagacatgcc cgccgcccag cgcgtcgagc
     6541 agatcgcccc ggccggcgcg ccgcaggtgc tgcaggactt cgacgcggcg atcgtcgcca
     6601 gcctcaaggc ctcgaacgcc cgcttcgact acgacgacgg cgacggcgtc agctgtgcgc
     6661 tgcgccgcgg ctcgtggagc gccgccctcg gcctcggggt ggtgttcgtg ttcgcctgga
     6721 ggggccgccg gcgccggcca gcggcgtgag ccgggtgtcc gaagggacag gcgcgcgctc
     6781 gcggcggcgt cgtcgcgggc tcggctggca cggacgatgt cctcgcggac aggtttgaag
     6841 agacaggccg ccggtccgtg ccaggcgcgg ccgtctcagg tcggctgcag gagcgcggtg
     6901 atctcgtctt cgggcgcgtc gcggcggcgc tggctgaagg tgatgaccac cttgtcgccg
     6961 ccggcttcga ccaggtcgag ctggtcgacg tcgccggtgt gcgggtcgag gtggaccacg
     7021 aggtcgcgga tctcccggcg ggcggggtgg tcgcggcgcg gggtgatcgc cagcaggtgg
     7081 ccggggccgc gggggaccgt caggcgggcg tcgagctgca gcgcggcggc cggctcgccg
     7141 gcgccctcgg ggacgctgaa gagcgcgagg acatgttcga acagccaggt gaccgtcggg
     7201 ctcggggcct cggcgagggc aggcagggcg gggtcgttgg gccggatctc cagccgcccg
     7261 cgcgacaggc gggtggtcac ccccgcgcgg gtgtcgtcgc gcaggaccag agtgtcgggg
     7321 gcgcgcgcga gcagcgtgcc cgccgtcttg agcggctcct gcagcagcgt cgactggcgc
     7381 gtgagcgcgt agcgggccac cagcacccgc gtgcccgcgg ccgccttggc ccacagctcc
     7441 agccgtcgcg ccagctggcg atcgacgacc ggggcctggg cgcgggcgcg gccggccgtc
     7501 agcgcgaggg cgccggcggc gaggcggagg aacgagcggc gcgggcgcat ggggtcaggc
     7561 gggcggagcg gggcgggtcg agaggacatg tgtcatggga caggttcttt tcgacatggc
     7621 gcaatgggcc tgtccctggg ggcctgtgcg gacgaacatg tcttgaggga cctggcgcat
     7681 caggcatctc gggtggggcg gcggacgaag cggtcggcgg cgcggctggt gagggagtag
     7741 agcagggggc cgacgaggcc gccgacgccg tgggcggcga ggacggccag gccggcggcg
     7801 atgccgagcg agcgccagac cggctcgggg gcggccagga gggccagggc ggcggcgagc
     7861 gggccgaggg cgttggccag gcggccgggg tcgatccacg ggcggccggc ggccagggcc
     7921 tggacggcgc gcaggccggc gaccaccgcg gccgagccgg ccagcaggaa cacggggagc
     7981 gtcagcgggc cgaacgagcg gtggagcagg tggagcagga cgagcaggcc gcactgggcg
     8041 acgatggccg ccagggccag ggccagggcc agggccaggc gccgcgtcgc cagccacacc
     8101 accagcgccg acagccacgc gccggcggcc gcgacggcgc cggcgcgggc ggagaagcgg
     8161 tcgtgttcgg cgcgggcgaa cacgccgggg ccgcggaggt cgagcgcggc cggcagggcg
     8221 gcctgttcgc cggccaggta gacgcgggtg agcacgccgt cggggccgaa cttggcggtc
     8281 agccacgggc cgagcgggcc ggccagcgcc gactcggggc tcggcgggtc gcgcaggtcg
     8341 tcgccggcgc cgcggatgaa ctcgccgaac gcgtcggggc gcatgccgaa ctcggcgatc
     8401 gtcgcgcgca gcagctcgag ccggccgcgg atgtcgagcg ccagcaggcc gtcgacgcgg
     8461 gccttgagct cgggctccgc gaccacgaac gcccccggcg cgtcgagccg atcgatctgc
     8521 gtcggcacca gcgccagcag cgacggcaac agctccgccg cccgcgacag cgcctcctcc
     8581 ggggtcgcgc cggggctgtg gatcgtcgcc acctcctcgg ggcggaagaa ctcggcgcgc
     8641 accgccgcct cggccgccgc cagctcgggg tcggccagcg gcagcgggct cgggctgtcg
     8701 aaacggacat gtctggaaga ccatgccccg agggacagga ccaccgcgca cgcggccgcg
     8761 gccgggaggg ccgcgcgcag gcgcagcggc ggcgggtcgg ggcggccgaa gggggcccgc
     8821 tccgcggccg gtttgccgag ccaggcggcg agcgcgggct ggaccaggcg gcgggccagc
     8881 ccggcggccg cgaggcccgc ggcccaggcg agaccccagg tctgccaggc cgggtacggc
     8941 gtgagaagga gtggggtcag cgcgagggcg gagagagccg taatcgtcca gtcggggcgc
     9001 gccggagcgg cggagatgcc gacggcgagc gcgagcagcg gcaggtcgag caggccgagc
     9061 ggcgcgacca gggccgccag cagggccgca gggccgagga tcgccagcag cagggcgacc
     9121 acggggcgca cgctgcggaa cgcgagggcg aggaccaggg tgagcgcggc ggcgagggtg
     9181 gtgagcaccc gcggagcggc ggccagggcc gcggcggccg cttcgtcgcg ggccggggcg
     9241 ccgaccacgg cgagcgagac ggggtggccg gcgacgagcg cggctgcgct ggcgcggagt
     9301 tcatgaaccg gagcgccggt gtggaagcac aggagggcgc tgcgcccgtc ggggctcacc
     9361 aggtcgccgc gaaccgtcgg ctcggggccg gcggcggcca ggaagccgag gctcgcggag
     9421 cgctgggggg cgagctctgc gaggcgcagc gggtcgcggc gcaggtcgtc gccgacgagc
     9481 ccggcgaacg ggctggcgag cctggcccgg gccccggcga tcgccgtacg cagggcctcg
     9541 ggcgcgagcc ggtcggcgag ggcggagtgg tgctcgcgcg gcagcagcga gagcgcgtgc
     9601 gcgtcgagcc agcggcgcgc ctcggccggc ggcggggcca gcgggcaccg tccggcgagc
     9661 ggctccagtg ccgcgatcgc ggcctcgagg gcctcgtcgg gcgcgccgtc gtcgaggtgg
     9721 acccgcaagt cgatctcgat cacaggtcga tgcgctgcgg ggatcagacc ccacacctgc
     9781 gcttcggtgc ctcgagcccc cgcgacgagc cccagcgcgg cgcaaacggc gagccacgcg
     9841 agggccgtga gggtcgggcg agggggcacc tgtgcagaag tatatcacca ccgaatggtg
     9901 aggttgaagc ggctgcgata cgtgccatga agtggcatca tcacgggata agcttggaat
     9961 gggttgggat ggatcaccgg gaccgctctt cggaaccaag atgtcctcgc tgctacagcc
    10021 ctcgatcttc gagccgcaag ccgcccctat caatcgctac gccgagctcg tggagcgcga
    10081 gggcatcgcg tgggtgctgc ggttcttccc ctcggtggcg ctgagcccgg gccgcctgcg
    10141 caagctgcag gccgcgaagt tcgcccgcct ggcggcgcgc gggctgccgc gggcgccgct
    10201 cgccgagctg cgcctggtgt gcgactggat cacctggctc ttcttctacg acgacgcgct
    10261 gtgcgacgac gtcgtcgccg cccccgagcc gctcaagcgt ctgcacgagg cgcaggtgcg
    10321 gatgtccgcg gtgctccgcg gcagccctgc gctcgaggac gacgagccgc tcgtgcacat
    10381 gctcgcggag ctcggcgcac gcaccgctgc gtgggctgcg ccaggcttca tgccgcggtt
    10441 cgtcgccgag gtggagcgct attttcagag caacgtgtgg gagctgcgga acctgctgca
    10501 ccagctccga cccgcgctgc cgatctacct gaagatgcga cccttcaccg gcgcggcggg
    10561 cgtggtgttc gcgctcatcg agctcatccg tcacgagtcg ctcggagagg tccgccagca
    10621 cgtggtcgta caacagctcg agctgctggc caacaacgcc atctgctggg ccaacgacat
    10681 cggctcgctc gagaaggaga tggtcgagca gaacccgcac aacctcgtgc tcgtgctgca
    10741 ggccgaccag ggcatcacgc tcgacgaggc cctggcccgc gcggtggcga tgcaaggcgc
    10801 cgaggaggac gcgttcgacg ccctcgccgc cagcctgcgc gactacgacg ggctctcctc
    10861 acccgcagtc ctcggctacg tcgccgacct ggggtctttc gtccgcggca acttcgtgtg
    10921 gatgcaggag acgatgcgct accgcgcccg cctcagcatg cgcagctacg gcagcgctgc
    10981 ggcctgaaac cagcgctgcg gctcgcggcc cgcgctacgg ctggagctgc cgctcgagag
    11041 ggcgctgctg cagcttcgcg actcgaggca ggcctgcagc gccagcgtcg cggcgctcgg
    11101 ggcagcgtgc tggacgctgc ggtggatgcg tcctcgaggc tcgcgcggca ctggagtgtg
    11161 tgacgggcga gtcctcggca ggcgaaggtc gcgagtccgc ggcgaggcgc gaggtgacgg
    11221 ctcgcaacgc gactcgagtc gcgaccgcga gcccctggcg ggcgacgcgg gggccagggg
    11281 gcaggcgctg cgcgaggacg gcagcggcag cggggagcgg cgcaggcctc gcgagctgcg
    11341 gcgcggcgca cacagcagcg ccgatgctgg aggaccagcg ttgccgccgg tgacgtcgcg
    11401 gccgctcggg gcgcgggggc cgtgagggcc gcgggggacc tgcggcgctc gcggcggcag
    11461 gttcgctagt ccggcggggt cgtgctaaag aggacgggtc gtccaggcct gtgccgagct
    11521 ccctctggaa cagactccgc gccgcgatgc tctggggggt cccctatacg ggctcgccgg
    11581 ccctcgcggc gcgcgtgatg ttgaccaacc aagtcttcgt cgtctgcctc gcggtcatcc
    11641 tcgcgtacat ctgcctgttc gtcgcgctcg gcctgtacac ggaggcgctg acggtcatcc
    11701 cgttctggct gtcgtacctc gcgtgcatgt tcgccaacaa gttcgggtgg ttcaacgtgt
    11761 cgcgcatcgg cctgtgcatc tgctgctgca ccgcgatcgt gttcttcgcc tcgatgctgg
    11821 gcgagccgtc gggcctgcag ttcatcatgt tcccgatcat cggcttcccg ctggtctgct
    11881 tcgaggcgcg tgagcggacg cagatcgtgt tctgcatggc ggtggtggtc atcagcttct
    11941 tcgtcggcga gctgtccgac tactcgctgg cgccgcgctc ggcggtcacc tcggcggccc
    12001 agcactggat ctacctgctg atgatcctga cgaccttcac gctgacgctc gggccgacgc
    12061 tgctgttctt cctcgccagc caccgcgccg agggccggct catccactcg aacaccgagc
    12121 tgcagcgcgt caacgaccag ctgaaccgcg cccgcgacga ggccatccgc gccaaccagg
    12181 ccaagagctt cttcctcgcc aacatgagcc acgagctgcg cacgccgctc aacgcgatca
    12241 tcggctacgc cgagctgctg cgcgacgagc tcgaggacga gggcgtgcgc gcggccagcg
    12301 tcgacctcga gaagatccgc ggcgccggca agtacctcct caacatcatc aacgacgtcc
    12361 tcgacctgtc gaagatcgag gccgggcgca tcgacatgtt ctgggagacg ttcgcgctcg
    12421 acgacctcgt cgacgacgtc gccggcatga tccgcccgca ggccgaggcc cggcgcaacc
    12481 gcctcgagct ggtccgcccg cccgcggggc tcggggcggt cacggtcgac aagacccgcc
    12541 tgcgccaggc gctggtcaac ctgctgcaca acgcctgcaa gttcaccgag gccggcgtgg
    12601 tcaagctcgc ggtcgcgcgc gagcccggcc gccagggcga cgcgatcgac gagtgggtgg
    12661 tcttcaagat cagcgactcg ggcatcggca tgtcgccgga gatcgtgcgc gagctgttcc
    12721 aaccgttctc gcgcggcgat ctcgagtcgt cgcgcaagta cgagggcacc gggctcggcc
    12781 tggcgatcag ccgccgcctg gtgcggatga tgggcggcga catcaccgtc gagagcaccc
    12841 cgggcatggg ctcgaccttc accgtgcgga tccccgctca cgcgaccctg gcaaattcga
    12901 gcggcagcgg ctcgcagacc gcgaccggct cgcaggtcgc cgtcgtgagc agctcctact
    12961 cggccagcgc cagcagctcc ttctcgtgga tcgggggctc gtgaggcggt ccccggcccg
    13021 aagccgcgcc cggcccgcga tccggcgagc cgatgctccg gtgatttcgg ggctcgacgg
    13081 cccgcggcat ccccgtgcta aggtcggccc cggggggcgg tgaacggtga agacggcgcc
    13141 gagcaagcgg gggccgacgt cgaacaagta cgcgctcgag ctccacggca agccgtgcgg
    13201 gtggctcacc gacgtctcgg gcgccctcgc cgtcggtgag ctcggcggcg aaggccggcc
    13261 cgaccgctac gaggagctga cgctgcgctg ctggccgggc atgccgcacg agttctacgc
    13321 atgggtcgcg gcgtcgatga cgagccggcc gacgccggcc cgcggcgagg tgatcctcgc
    13381 cgacgacggc aacgccgaga tgagccgcct cagcttcgtc ggcggcgtga tcaccgagct
    13441 ggcgctggcc tcgtacgaat atggctttcg ggacagcttg aagctcaacc tcaagttcag
    13501 cccgcacagc tcgaagcgca gctacgcggg cggccacctc ggcggcgagg tgatcgaggc
    13561 ccgaaggccg ctgcccgcca ccgaccccga gctgcacatc gacggcctcg aggaggcgtg
    13621 cagccaggtg cggcggatcg agggcctgac gatccgccag cgcatcgagc ggccgcccgg
    13681 cgacgacggg atatacacgg tccgccgggt cgcgccggcg gtggtcggcc ggctcgcgct
    13741 ggtgctggcg gagaacaagg cgctcgggtt cacgcgctgg ctcgaggcgg tcgaggccgg
    13801 gcgcagcaac gggcgcgccg cgaccttgac gcttggcgcg cccgcggtcg gcttcaccgt
    13861 ggtgctgcag caggtgcgcc cggcgcggat cgtcgaggag ccgggcgagg tcggcgacag
    13921 ccgccggcgc gagctgcggg tcgagctcga cgcccgcggc gtggagttcg cgttcgcgcc
    13981 ggtccgcgaa gccgtggtat aggcccggca tcgtgcagct gaacccggcc cagcaggcgg
    14041 cggtcgagca ccgcggctcg ccgctcctcg tgctcgccgg cgcgggcacc ggcaagaccc
    14101 gcgtgatcac ccaccgcgtc gccgcgctca tggacgaggg cgtgccgccg tggcggatcc
    14161 tcgccgtcac cttcaccaac aaggccgccg ccgagatgcg cgcgcgcatc gagaagatgt
    14221 gcgagggcaa ggtcgacgtg tcgcagctgt gggtcggcac gttccactcg atctcggcgc
    14281 ggatcctccg tcgccacggc gagtcggtcg gcctgtcgcg caacttcgcc atctacgaca
    14341 ccgacgacca gacccgcctg atgaagcgcg tgttcaagga gctgaaccgc gacgaggacc
    14401 aggtcaagcc gcgggcgatc ctcggccacc tcgaccagct gaagaaccgc ggcctcacca
    14461 tcgaccaggt cgaccagctc gggctcgagg gcttcatgac ccgcctgacg gcgctgctcg
    14521 gccgccgcta ccaggagctg ctccgcgccg ccgacgcggc cgacttcggc gacctgctgg
    14581 tgctcgcggt caagctgctc gagaaggcag gtacggagca gccgcggccc ggggcgcagc
    14641 tggtcgacgt cgacccggtg atcgggctca agcggcggtt cctccacgtc gtggtcgacg
    14701 agtaccagga caccaacccg gtgcaggcgc ggctggtcga gctgctgtcg ggccgggcgc
    14761 agctgtgcgt ggtcggcgac gacgaccagg cgatctacgg ctggcgcggc gccgacgtgt
    14821 cgcagatcct cggcttcccc gaccgccagc ccggctgcga gctgatccgc ctcgagcaga
    14881 actaccgcag caccggccac atcctccgct gcgccgacgc gatcatccgc cgcaacgagg
    14941 gccggctcgg caagacgctg tggagcgagc tcggcgacgg cgcgctggtg accctgcgcg
    15001 cctgcgagga cgagcgcgag gaggcccgct tcgtcgtcaa cgagatcctc gacgcgctca
    15061 acgaggacat cccgccggac gagatcgcgg tcttctaccg cacgcacgcg cagtcccgcg
    15121 tcatcgagca gcagctcacc gacaacggca tgcgctacgc gatcttcggc ggcctcgggt
    15181 tcttcgagcg caaggagatc aaggacgcgc tggcctacct gcgcctgctg cagaacccga
    15241 acagcgacct cgacttcacc cgcatcgtca acgagccggc ccgcgggatc ggcgacacca
    15301 ccgtcggccg cctcaccacg ctggcggcca accgcaacgt ctcgctgctc accgtggcca
    15361 ggagccccga ggaggccggg gtcagcggcg ccgcggccaa gcgactgcac gtgttcgtcg
    15421 ccatgatcga cgagctcacc gcccgcctgc acgcgaaggt gccgctcggt cagctcgccg
    15481 ccgaggtgct cgaaaggaca ggttatcgcg acgccctggt ccacgagggc agcgaggagt
    15541 cggaggcgcg ggtcgagaac ctcgacgagt tcgtcggcgc gctcaacgac ttcgcgcagg
    15601 acaacccgga ccagacgctg gccgactacc tcgagcaggt cagcctggtc agcgacgccg
    15661 acggcggcgg ccacggcgag gtccgagccg tgcggttgat gacgatccac agcgccaagg
    15721 ggctcgagtt cgagaaggtc atcctcaccg gcatggaaga gaaggtcttc ccgcactcgc
    15781 gggtgatcgc cggcgaggag gcggcgcgcg aggagggccg gcggctgcgg cccgaggagc
    15841 gggcgcagat cgaggaggag cggcggctcg cctacgtcgc ggtcacgcgg gccaagcggc
    15901 agctggtggt gacgtgggcc aagcggcggc ggctctacaa ccaggagttc atcggcacgc
    15961 cgtcgcgatt cgtgcgcgac ctgccgccgg actcggtgcg ggggcgggtg cccggggtgg
    16021 tccgccgcga ggcggtcggg gtgccggcgg ggctgtcgtt gccgagcgcg ccgccgcgag
    16081 cgccggcgcc cgcgcgcgag tcgtcgtgga acagcgacat cgtctacgac gagggggtcg
    16141 cggccgcgcc gacgcgccgc gggcccgccg cagtccaggg cgacgcgccg acgctgtaca
    16201 agggcatggc ggtgcgtcac cgccagtacg gcgagggaac gctggtcggg tgggacggca
    16261 ccggcagcaa cctcaagctc gccatcaact tccccgtcgt cggcgtgaag acgatcctgg
    16321 cccgcttctg cgagccgctg tgatcctctc ccggccacag tgctaagctc ccggcgatgc
    16381 tgcgcgccat cgtcgtcgtc gtcctcgccg ccgtcgcggc cacccccgcc tgcaagggct
    16441 cggaatccgc gttgccggcc ggcgaggtcg gcgggggcga gccgtcgcgg gtccccctgg
    16501 tgcccaagga ccatgccctt tacgccaggt tcgaagggac agcttttgag aacgcctgca
    16561 gcgacgacgc cgcctgcagc aagggcggct gctcgagcga ggtgtgcgcc agcggcgatc
    16621 agccgcccgg cacctgtgac gtgccggagg tccagatccc cgcggcggcg aactgcggct
    16681 gcgtcgccgg cgagtgcgtg tggtggtccg acggcagcct cactctggcg gccgccgccg
    16741 agaagccgac ccccgccgag caggccggcc cgcgctgcgg cgacgtcacc tgcgccgccg
    16801 gtgagacctg catcgagtac tacggcatcg ccggcccgcg cggccccaag ttccagacct
    16861 gtgggatccc ctgtccccac ggcaagtgcg ccgatggcaa gaagtgcatc accatcgccg
    16921 acgggcccgg gcccgtgtgt cagtgacgac gcacggccga gcccgctgtc acgcggacgc
    16981 gtccgccgat gcgtgtgcca tgaatgtcgc gaatgccggg atctcgagcg tgctttcgag
    17041 gtccgcgagg ctgtctgaag ggacaggccc gaagcgccag gcgatccacc gggagtgacg
    17101 gccagacgcg aacgagagca gttcgcccgg acgtggggtc cgtgagggac acccgcgggg
    17161 ccggcgaaac cgcgcaactc tgcttgtggg gccgcgcgcg ggcagttagc gtcgcgagca
    17221 tgaagctccg atcgctcacc ccgctcctcg tcgtcctgat ggcgccgatc gtcggttgca
    17281 ccaaggacga caacaagaac acctcgacct ccgacggctc cggcggcggc gcgtgggcgg
    17341 tcggcgagga cgcgacgatg gtccgcctca accccgcggg cgatgtctgg tactacccgc
    17401 tcgagatcga gggcgacctg ctggcgatcg cgtgcaaggg ccaggagacc ggcatggcgg
    17461 tcggcgagga cggggtggtg ctgcgcaccg acgacagcgg cgagagctgg acgcagatcg
    17521 acgtcggcac gcgcgcccgc ctgcgctcgg tgatcttctc cggcacgacc ccggcgtaca
    17581 tcgccggcga cggcatcgtg ctccgctcgg atgacgacgg ccgcagcttc acgccggtgc
    17641 ccgacgccga gggcgacttc acggcggtga cgacgacggc gaaggggacg ctcgcgtggc
    17701 tgacgacggc gagcgggcag atctggcagc tcgacgggga gacgctgacg cccgtgttca
    17761 cgacgtcgga gggcccgctg tcgggcatcg cggcgacgcc cgacggcggg agcgtggtgg
    17821 ccgtgggcgc cggcggcctg gtgctccgct ccgacgacgg cggcgcgaag tgggcgagcg
    17881 tgacgacccc caccagccgc gacctgcacg cggtacgaat ctcccgcacc gccgacctcg
    17941 tggtcgcagt gggcgcggcc ggcgtggtgc tgcgcctcga cgacgagctc ggcgccagcg
    18001 ccgaggagct gctcgagcct ggcctcgcgc tgcgagccct gcacctgtcg atcgacggcc
    18061 acggccacgc ggtcggcgac cacggggtgg tcgtgcactc gaacgacgcg gggctggcat
    18121 gggaggcgct cgacctcggc ctcgaggagg cgctgttcgg cctcgacgac ctgcacggcg
    18181 aggcgcacct gtgagaattt ttaaagatta acaagtaggc gcgagggaca ggcacctcat
    18241 gcctcgcccg ctctcgtgcg gagagcggtg gcgtggatgg cgggcgggac atgtccctcg
    18301 cgtcatgaga gaaagggcat gtccgtgagg acatgccctt tcgtcatggt agaccagcgg
    18361 cgcctcggtc acgcctgcag ccgcaagccg cggcgcgagg atggcgcgaa ggagtggccg
    18421 tcaggttgtc cggcgaggtt gtcgtcgtgg cgcggcgagc cggcgatccc cgcgtggaat
    18481 tcgagtcgcc gcgagaatgg cgcgctgcgc catcgcatgt ccgggaggcc atgggctggt
    18541 gcggcgctcc gtcgatcccg cgtgcgatgc gagtcgcggc gagctgtcga cccgcgtgca
    18601 gggtcgcagc gagaagggtg cgacgtggcc accgcgccat ggtttgtgcg gggacatgcg
    18661 cagcaagtcg cggcgcggcg agccatcgtg cagctgcaag ccgcggcgag aagggcgcga
    18721 aggacgtggt cctcgcgccc ctctctcggg acatgttttg agagacatgt cttcggcgcg
    18781 gcgagcggcg cgctgggtca gcgcttctcg ggctcgacgc gggtgaagtc gggctcgtcg
    18841 ccgctctcgg cgcgggtctg ctcgcgccgc tcctcgccgc cttcgctgcc ggtcacgccg
    18901 ccggcgctgc cctgcgtcag ctgggcgcgg tactcgtgga aggaggtgcg ggcgcgttcg
    18961 atggcgtcgc ggatcgactc gagggtggcg tcggtggcgg tacggatctg ctgctcgagc
    19021 ttctcgatcc ggggctccat ctgctgctcc cagcggtcgc gggcctcctt gccggcgagg
    19081 ttgagtcgga cgcggatctc gtcgcggagc gtccgtagct cctgcatgct gttctccagg
    19141 gtatttctca gggaggtcat cgcagtctcc ttggcgccgg tggttcggcg cggccgcggt
    19201 ggttatgctg cgcctcgcat gcagcgcaac cgaactggac cacagcgacg gagggcgacg
    19261 tgcgcgcccg cggtctgacc cgccggacct ggctcgccgg ggcatcggcg ctgatcgcgt
    19321 gccggccggg cgggggcaag accgcagcga cctgtcctcc ggaccaggcc ggtggtctgc
    19381 tggtcgtccg caacggcacg atctggaccg gcgatccggc cgagccgaac acccgggcga
    19441 tcgcggccgt cggcgggcgg gtgatcgctc gcggggccgc ggccgagtcg ctggcgcgcg
    19501 actgtccccg aggacaggtc ctcgatctgg ccggcggcag cgcggtgccc ggcctcaccg
    19561 acgcccacgc ccacctggtc gggctcggct cggcgctggt cgaggtcgac ctccgcgggg
    19621 cgcgatcggt cgaggaggtg gtcgaccgcg tgcgccgcgg cgccccgccg gacggctgga
    19681 tcaccggccg cggctgggat cagaacctgt ggccgggcgc ggcgatgccg acccacgatc
    19741 cgctgacgac cgcgttcccc gagcgaccgg tgtggctgcg tcgggtcgac ggccacgccg
    19801 gctgggccaa cgcggcagcg ctgcgcgcgg gcgacatcac cgcggcgacg gaggtgccga
    19861 caggcgggga gatcttgctg cgcgaggggc catcggggcg cgagccgacg ggggtgctgg
    19921 tcgacgcggc gatggacctg atgccggtgc tgccgccgcc ggggccggag ctgcgccggc
    19981 ggctgctgct ggcccaggac tacgcgctgg cccgcgggct ggtgggggtg cacgagatgg
    20041 gcgtgggccg ccacgtggac gcgctgctgc gcgagctggc ggccgagggc ctgctcaagc
    20101 tgcgcctggt cggctacgcc gacgagtcgt ggttccgccg gggagatggc cttccggacc
    20161 tggccgatcg gccagccatg gacgaccgct acgcgctgca gggggtcaag atctacgtcg
    20221 acggggcgct cggcagccgc ggggcggcgc tgctgcagcc ctacagcgac cggccgggcc
    20281 acaccgggat gttccagcac gcgccgggcg agctggccgc ggtggtgacg cgggcgctgg
    20341 cgcaccagta tcaggtggcg gcgcacgcga tcggcgacgc ggccatccgc gcggtgctcg
    20401 aggcgctcgc gggcgcacgg ccgccggccg atcaccgcct gcgggtcgag cacgcgcaga
    20461 tcgtggacct cgccgacatc ccgcgcttcg ccgagctcgg ggcgatcgcc agcatgcagc
    20521 cgacccacgc gaccagcgac atgccgtggg ccgagcagcg catcggcgcc cagcgcctgg
    20581 ctggggcgta cgcgtggcgc cgcttcctcg acgcgaaggt gacgctggcg ttcggctccg
    20641 acttcccggt cgaggaggtc gagccgacgt tcggcctcta ttctgcgatc acccgccagg
    20701 acgccgccgg caacccgccc ggcggctggc tgcccgacca gcgcctgacc ctcgccgagg
    20761 cgctggcggc gttcacccgc ggggccgcgt acgcgagccg acgcgagcgc tgggccggga
    20821 cgctggccgc ggggatgctc gccgacgtga cctgcttcga gggcgacatc acgaagatgc
    20881 aaccgctcga gctgcgcacc gcgaaggtgc gcgcgacgat cgtcggcggg gaggtcgtcg
    20941 cgccgaagtg agggcgggcc gcggagagct tttgtccggg cgtcgac
//
