LOCUS       NZ_CP114040            20882 bp    DNA     circular CON 26-AUG-2024
DEFINITION  Nannocystis poenicansa strain FL3 chromosome, complete genome.
ACCESSION   NZ_CP114040
VERSION     NZ_CP114040.1
KEYWORDS    RefSeq.
SOURCE      Nannocystis poenicansa
  ORGANISM  Nannocystis poenicansa
            Bacteria; Myxococcota; Polyangia; Nannocystales; Nannocystaceae;
            Nannocystis.
REFERENCE   1  (bases 1 to 13228663)
  AUTHORS   Ahearne,A., Stevens,C. and Dowd,S.
  TITLE     Minimal conservation of predation-associated metabolite biosynthetic
            gene clusters underscores biosynthetic potential of Myxococcota
            including descriptions for ten novel species: Archangium lansinium
            sp. nov., Myxococcus landrumus sp. nov., Nannocystis bai
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 13228663)
  AUTHORS   Ahearne,A., Stevens,C. and Dowd,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-NOV-2022) Biomolecular Sciences, University of
            Mississippi, Faser Hall 407, Oxford, MS 38655, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2021
            Assembly Method                   :: IPA v. 10.1.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 250x
            Sequencing Technology             :: PacBio Sequel IIe
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_026965555.1-RS_2024_08_26
            Annotation Date                   :: 08/26/2024 12:45:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,229
            CDSs (total)                      :: 10,129
            Genes (coding)                    :: 10,068
            CDSs (with protein)               :: 10,068
            Genes (RNA)                       :: 100
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 9 of 61
            Pseudo Genes (incomplete)         :: 52 of 61
            Pseudo Genes (internal stop)      :: 2 of 61
            Pseudo Genes (multiple problems)  :: 2 of 61
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:28:22
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1256891
            Orig. end                         :: 1277773
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP114040.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20882
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="2"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20882
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20882
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10882](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10882)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            1118..1309
                     /locus_tag="O0S08_RS04855"
                     /old_locus_tag="O0S08_04855"
     CDS             1118..1309
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS04855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_04855"
                     /product="hypothetical protein"
                     /protein_id="WP_269037809.1"
                     /transl_table=11
                     /translation="MTPLVLLLLLFLGFGLFGVLSDRACRAESLRRGREERRVTLKDFV
                     VPVVPVRHRWLRPRVHRG"
     gene            complement(1239..4172)
                     /locus_tag="O0S08_RS04860"
                     /old_locus_tag="O0S08_04860"
     CDS             complement(1239..4172)
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012298.5"
                     /locus_tag="O0S08_RS04860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_04860"
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_269037810.1"
                     /sec_met_domain="Pkinase (E-value: 1.5e-44, bitscore:
                     151.6, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFPPLPTEDIASTLPQLARTRPLDAEAMRRRIGARLFGEDTAPMQ
                     LGRFRILRSLGVGGMGVVYAAEDDTLGRVVALKMIRDDVLVSDADRRRLLHEARALARL
                     SHPNVVQLHEVVTAGEAVCLVMEYVAGTTLSQWLRTEPRDVAAIVDVFVAAARGLAAAH
                     RAGIVHRDVKPGNILVGDDGRVRIVDFGLARGAAAVDSPTIAELSGSTTDPGARATDTG
                     TVAGTPAYMAPEAFSTGRVDASSDQFSFCVALHECLYGDRPFGPRSVPGRELAYRAIEL
                     PAGAGQRRIPRALRRLLARGLAVRPADRFTSMDVLLGALEKQSFRLVRSLLLPLVLLLT
                     GGLIAAAIIPFDAFSPGLCPEPRDQLEGIWDFQTKAAVRTAILATAQPFSLQTADFVQS
                     RLDAYVEEWLDAHVQVCEEIQGRNEQALLLFERSELCLAHRRSALDALIEQLRHADAAL
                     VASVPELVHRLPDIRVCRDREALLDGSYKRPRDPRLAPAEAALAHATSLHAARLGVEAL
                     AQVDAALAAIRAVGDPLLEADALRLRGVLLGHHLGDVRGGLQHLHAAGVLATGSALDGL
                     AWRVWNDLAVFAARVEQDGERARQYLEYARAAATRHARLTPNDRADLLDTDGHILFLED
                     QNLEALSRHREAYELRRDFLDARHPELIWAGLRLANATANAGEPELAMKLFDELKRDAL
                     EIFGREHPAVVRVELAEAQLLAELDQTGPARSCFADARPILLRTYGPDTILLARVELEL
                     AHIDFAERQFALATARARTVLGYPESSVPAQHQLRVEALALLSDIFLEAHQPSTSVEVY
                     RALLTWHDDGRVELDLEALLYSLGAALCELQRCGEGFGYFSRLNALYTNNPPEHPEHRA
                     FVLYGLASYHLENRQPEIALPHLEEARRLTETDDADRYVRMDVARLLSRCLTALKREPQ
                     RARRLQLEADALARRSSTAASLDALSRDGPAAAASGVAPAPPAPRSP"
     gene            complement(4179..4565)
                     /locus_tag="O0S08_RS04865"
                     /old_locus_tag="O0S08_04865"
     CDS             complement(4179..4565)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O0S08_RS04865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O0S08_04865"
                     /product="hypothetical protein"
                     /protein_id="WP_269037811.1"
                     /transl_table=11
                     /translation="MNDSTSTTVDRYEDLPAGELPTIRYDKGGYVERSFDVAGARVSAV
                     KLEPVAPEHAQQAKSLQITPVEGSGWVELGHGTILVFFTHPPLGQEHAWRLCFFDGTKP
                     TGTKITVKIRKTRIGDRDLESKDS"
     gene            4657..5271
                     /locus_tag="O0S08_RS04870"
                     /old_locus_tag="O0S08_04870"
     CDS             4657..5271
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006976627.1"
                     /locus_tag="O0S08_RS04870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_04870"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_269037812.1"
                     /transl_table=11
                     /translation="MASDIELFRAWRAGERQAGSVLFARHFDSIYRFFRNKVDGEVEDL
                     VQRTFVACVEGRERFREESSFRTYLFAVAHNLLRDHLRRKKRAAEQLDLEEVSVVDLGA
                     SPLSFLAAHAEERVLLHALRRIPVASQIILELYFWEQMTGPEIGAFLGVIEDTARSRIR
                     RAKLQLEAMIRTLEATPAELESTLSNLDGWAEAIRRQLAPT"
     gene            complement(5466..6569)
                     /locus_tag="O0S08_RS04875"
                     /old_locus_tag="O0S08_04875"
     CDS             complement(5466..6569)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012321.5"
                     /locus_tag="O0S08_RS04875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_04875"
                     /product="VWA domain-containing protein"
                     /protein_id="WP_269037813.1"
                     /transl_table=11
                     /translation="MVAVMAGCGGVGGTPGTDTDTGSSTTGIPGVTSVSAGATETGPTT
                     GSTTDEAVKFDLGGGPGSATDSEGASDTSVCADADVTFEPQIPTVLLLIDQSGSMTTQF
                     GNTDRWEAVYNALLDEDDGLVPHLEGQVRFGMALYTSFEGDQGGECPVITETPPALDNY
                     QAIAASWDASQPEDETPTGESIAAVTPTLVMDPTEGNKIIVLATDGEPDTCAEPNPQNG
                     QEESVEAAAAAFAQGVRTYVISVGNEVSDQHLQDVANAGAGVGPGDPDAPFYKADDAQA
                     LADAFADIVDGVRDCKLTLDGTVSEGGEDQCTVYVNGMVVPFGDEDGWQLNNPGEVELV
                     GDACDAIQNGEVQVSIKCACGVVVPPG"
     misc_feature    complement(6806..6815)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.08"
                     /tool="antismash"
     gene            complement(7117..8682)
                     /locus_tag="O0S08_RS04880"
                     /old_locus_tag="O0S08_04880"
     CDS             complement(7117..8682)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014380757.1"
                     /locus_tag="O0S08_RS04880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_04880"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_269037814.1"
                     /sec_met_domain="DAO (E-value: 4.3e-13, bitscore: 48.8,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLGISRRPANTPDRRAPVALPRPLDVLVVGGGIAGLAAATILAER
                     GARVTVLEPETYLGGRAGAWTDTLADGTEFEMERGFHAFFRQYYNLREWLRRIDPELGF
                     LRPVEDYPLLGPDGLRESFAGLPKLPIWNLVSLIRRSSTMTWRDALRVDDTCGRAIMAY
                     DPLATYAQFDREDARSFLDRLGFPPRARQMLFDVFAHSFFNPEQEFSAAELLMMFHFYF
                     VGNPEGIVFDVARGPFSTTLWRPMAAVLERRGVRLRLAEAAVNFDRGPDGRHRVTSSRG
                     QVYHADACILAASVPGLQQLVAESPHLGYPRGVAPEDPCIGHCWREQVAAQTVTARFAV
                     WRLWLDRPPAPGRAAFVGTTGLGLVDNISLYPLFEDESRDWAARSGGSVVELHAYALPD
                     ELDEAEIKADLLRALHDLYPETRDAATLDERFLLSQDCPAFRPGTHPLRLRVDTPDPTL
                     YLAGDCIHTPFPTALMERAASTGILAANHILHHHGAAEEPLWSVPPRGPLARLIHRKAL
                     RDRG"
     misc_feature    8684..8697
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.08"
                     /tool="antismash"
     misc_feature    8685..8694
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.85"
                     /tool="antismash"
     misc_feature    complement(8685..8698)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 18.43"
                     /tool="antismash"
     misc_feature    complement(8686..8699)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.58"
                     /tool="antismash"
     misc_feature    complement(8687..8700)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.22"
                     /tool="antismash"
     misc_feature    8688..8701
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 17.65"
                     /tool="antismash"
     misc_feature    8689..8702
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 17.22"
                     /tool="antismash"
     misc_feature    8690..8703
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.96"
                     /tool="antismash"
     gene            complement(8915..9637)
                     /locus_tag="O0S08_RS04885"
                     /old_locus_tag="O0S08_04885"
     CDS             complement(8915..9637)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019510370.1"
                     /locus_tag="O0S08_RS04885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_04885"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_269037816.1"
                     /transl_table=11
                     /translation="MTRPPPSLRAQKQAVPHAFDRVAARYDLLTGMNPGYHRHLERSAE
                     RMRVPEDAALLDLCCGTGLSTLALVRTYPRARITGLDASVGMLDLARKKRELTGVRFLQ
                     GDAMDPAAYGASGPFDGILMAYGIRNMPDPDLCLRRLLPLLKPGGVICFHEYSVRDSLR
                     AHLVWNAVCLGIIIPAGLVTSPGSNIYRYLRRSVNAFDGAAAFLRRLQAAGFCDTQSAT
                     MDGWQEGIVHTFLARRPA"
     misc_feature    complement(9446..9448)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(10001..10882)
                     /locus_tag="O0S08_RS04890"
                     /old_locus_tag="O0S08_04890"
     CDS             complement(10001..10882)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013503665.1"
                     /locus_tag="O0S08_RS04890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_04890"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_269037817.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.5e-42, bitscore:
                     144.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDSRRRIDRALKSCLDQATAAPCPPRLGEAMRHAVFPGGARFRPE
                     FCLAVAEACGDAHPALVDAAAAAVELLHCASLVYDDLPCFDDAAVRRGHATVHAAFGEE
                     LAILAGNALIVLAFETLARAGGPHPHLLPGLLRVVARGVGGPAGIVAGQGWESEVGLDD
                     LGRYHRAKTGALFEAAVIAGAMTGGGDPLQWTGLGYRLGEAYQIADDIRDAYGRPELLG
                     KPVGQDRTHHRPSAVRELGLSGATLHLGELVDQAAGRIPTCAGRNDLLAHLRRWSEQLL
                     AAPPPLAASLRS"
     gene            11029..12594
                     /gene="crtD"
                     /locus_tag="O0S08_RS04895"
                     /old_locus_tag="O0S08_04895"
     CDS             11029..12594
                     /EC_number="1.3.99.27"
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017664708.1"
                     /locus_tag="O0S08_RS04895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_04895"
                     /product="1-hydroxycarotenoid 3,4-desaturase CrtD"
                     /protein_id="WP_269037818.1"
                     /sec_met_domain="DAO (E-value: 3.4e-10, bitscore: 39.2,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVVAKQSPRVVVVGGGAGGLAAAVDCARRGATVVLLERGAEVGGK
                     VRQEWVGGQSIDAGPTVLTMRWVFEGLFADAGAALAEHVQLQALTVLARHAWQDGERLD
                     LYADREATAAAITRFASAADASGYLAFCRHTEAIYQKVQGPFIRTAQPTLATLVGSLGL
                     RGLPGALGLDFHRTMWKALGDFFQDPRLRQLFARYATYYGSSPFEAPATLNLIAHVEQA
                     GVWAPAGGMSALTRAIAELARRHGAEIRCGAEVAAIEADDRVRAVRLTSGERLPADAVI
                     FAGDLAALAGGLLGAAPARAVKTPPKSRRSLSAMTWCLRGTAGGWPLAYHNVLFSRDYA
                     AEFTALMDRRALPAEPTVYVCAPDRRGGPPPAAAERLFVLVNAPPRGGEGWLTAREIEA
                     CERATWRVIERCGLSMAPAEPPRVTTPDDFAARFPGSGGGLYGTATRGLLDALGRPTAA
                     TKLPGLYVAGGSVHPGAGVPMATLSGRFAAATACAGLCSTGWSLRAATAGGTSTRSATT
                     APTG"
     gene            12525..13439
                     /locus_tag="O0S08_RS04900"
                     /old_locus_tag="O0S08_04900"
     CDS             12525..13439
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008064750.1"
                     /locus_tag="O0S08_RS04900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_04900"
                     /product="carotenoid 1,2-hydratase"
                     /protein_id="WP_269037819.1"
                     /transl_table=11
                     /translation="MVPPGGYGWWYIDALSDDGAHGLTIIAFVGSVFSPYYARARARAP
                     AGAADPMAHCAINVALYGPGVDAWVFTEYGASEVERRPEQLQVGGSSLTWEGDCLVVRF
                     DERTAVLGQRVAGTVRLYPSAFPDRPEPIDAHGRHTWFPAAPHAHVVAELTAPALTLRG
                     TGYHDANFGDEPLEAGFVEWSWSRAALSDRTVVLYDAHRCDGSQLQLGRVFHADGRVEP
                     LAAAHAMKLGRTRWWIARSTRTDGAPATVIRTLEDTPFYARTQVATRVGEVPVRAVHES
                     LSLSRFCSPLVQTMLPFRIRRVS"
     gene            complement(13485..14885)
                     /locus_tag="O0S08_RS04905"
                     /old_locus_tag="O0S08_04905"
     CDS             complement(13485..14885)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013811.5"
                     /locus_tag="O0S08_RS04905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_04905"
                     /product="alkaline phosphatase family protein"
                     /protein_id="WP_269037820.1"
                     /transl_table=11
                     /translation="MVDGLGHEAARTMGAIALLREHGQCRKTAVGVPSMSRPVYATIST
                     GLEQDRTGARGNDDESPLFAQSVWSLARGAGLSVAAVSELTWWRELFPGAFTSYDVLPL
                     DVDYFAAVPPADLQLVHPLYVDEAGHEFGAASREYAEAVARVDRELTGFLRTVDFSRDL
                     VILTADHGHSPRGGHGGAQEPIANVMTCHAGLGVRRDPEYGHLQITTVAPSLALLLGLP
                     FPAHMRAGDDDLDALWDLVDPAAFPPAYFEDRRAAVERFRRANEAAVRAWLPDSDGSWD
                     AFYEAHRAGHRRGARVLVAALALVFLLQLHLHRRRERQGEARSAALFGLGFVAVFGAVT
                     YALQVGLRGSFDLSSVAGRGEFIGFTLTLGLGWTSLAALVHWLVRRDRCALMLDLAAIL
                     LAGAVLSAAHPLVLGWHLGFPVPSPTVYFFPYFAALMFPAVAGVAVVVAALVGLRPLRR
                     RSDMLSRT"
     misc_feature    15075..15089
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.32"
                     /tool="antismash"
     gene            15096..16415
                     /locus_tag="O0S08_RS04910"
                     /old_locus_tag="O0S08_04910"
     CDS             15096..16415
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024662.5"
                     /locus_tag="O0S08_RS04910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_04910"
                     /product="DUF4056 domain-containing protein"
                     /protein_id="WP_269037821.1"
                     /transl_table=11
                     /translation="MRSAHANADDRREPPTTAARRLLAPLVAAITACAPTWKAPLTVDS
                     REVARALNDPADVVTDFDPAAVPVFDPPKKLRPCCAFGQDLRAEVGPVPVPLYKNENIR
                     SPEEIGPHGYDKGELTRERNGLVYTCRGGFLDIAHVRDTADRTLFLTLQLVRRLPEGAT
                     VEWPEEGTKRRVVVKPLPPGLLERHGRWKTATALASWAVYQLSTWHEVVTWYGFESVPG
                     VSERLSSFSPEDVYSNVLGINLAAGLILDGEIRSREEYDVAMQAWIREALRRLGAVPKD
                     KARAAMQAVDGLWWDSSKRVPEFTLVTRRYIHTDSPIPAWLVRDPAVREGCAGQPPPLP
                     LVIDHRLGDREISELASVEFEFGKWRPKNFPMPLAEGTTVTQADFPTITADIRHEGAAV
                     FGPDFDQPGEAQADRPDAKEKIVHRAVTDRRRRATTSAGP"
     gene            17090..18172
                     /locus_tag="O0S08_RS04915"
                     /old_locus_tag="O0S08_04915"
     CDS             17090..18172
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025167.5"
                     /locus_tag="O0S08_RS04915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_04915"
                     /product="HupE/UreJ family protein"
                     /protein_id="WP_269037822.1"
                     /transl_table=11
                     /translation="MGMAVGTCLLGLAIPRLAEAHQVGLSRGVYTVDGAVVEGDLTFAR
                     GELRALAPGLDGDGDGTLSEAEVAAGGAALAPVVAGIGVASDGEACVGTLTRASLTEED
                     GASLAIRFACPQPPESLTLTWSLFDALSTGHRHLGQFVRPGAGPEDILAEPVLHARAPA
                     ATVALAGGEAEAPARPVSAYFELGVEHILIGTDHLVFLLGLVVVGGRLRSLVAVITAFT
                     IGHSLSLALATLGIWTPSGAWVEPAIALSIAYVGVENFFVPDAAGRWRITLPFGFIHGF
                     GFAGVLAELGLPAGEVAPALLLFNLGVEAGQLAVLALVLPLLMALGRLPAYRQLQGARW
                     ISGAIVLAGLWWFFERVFGG"
     gene            complement(18304..19695)
                     /locus_tag="O0S08_RS04920"
                     /old_locus_tag="O0S08_04920"
     CDS             complement(18304..19695)
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S41"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015531.5"
                     /locus_tag="O0S08_RS04920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O0S08_04920"
                     /product="S41 family peptidase"
                     /protein_id="WP_269037823.1"
                     /sec_met_domain="Peptidase_S41 (E-value: 3e-21, bitscore:
                     74.9, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRSGSKLLFTAVVILTACAAPRSARVVRDHPGVWQSQGYGYVLT
                     VARGRVRLFDVAGDVCVEQRDLDASVLPFFDQVRLEPSGTTMVLSSALDPYEFRFTRLT
                     ALPPACTPPTADTPPANFAAFAEFFAHHYAFFSLYGVDWPSRVAAARERVSDATDDAAL
                     FAILRELVQPLTDSHIKIEAEFAGATHVHDGDEGPLERFLAADAARRGADPRQALQEFR
                     RTYWLDGIGRELLAGGGTIAANQRIQYGMLPGGVGYLAAVSMGGFVDGDYDSLRAELPT
                     LDAVMNDALALFEARNARAVIVDASLNIGGYDFIGLALAGRFAAAPAVAYTRRAADDPQ
                     SRGFAVRVEPAKGRRFTGPVYVVTSAETVSAGEILTLALRALPNVRHAGQSTRGAFSTV
                     LEKRLPNGWFVGLSNEHYTDPQGENWEGRGIPPQLPLAVFGPEGHDGHVAAIRTLLAQI
                     ADEVQ"
     misc_feature    20141..20154
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.4"
                     /tool="antismash"
ORIGIN
        1 acccggcgag cgcggagctc ctcgccgtcg cgcatgcgca ccccgaccgc ggtccccttc
       61 tcgagcaaga tctgggcgac gtcggccgag atccgcgtgt agccgccggc gtcggcgact
      121 gtctgcagca gctcgcgggc gatcgccgag gagccgccga ccgggtaata cccgccccac
      181 tggaagtgct tggtgacgag cgcctggatc gccagggagg cgcggctcgg ggtggcgccg
      241 tggtaggccc actgggcggc caggacggtc ttgagccggt ggtcgccgct gagccggtcg
      301 agcgcgtgct gggcggtctc gccgaaggcg cgacgggctg tcctcgtgaa catgtccgtg
      361 agtacatgtg cggaaggtgg ggcgagccgg gccaggtagt acgaccgcat cgccgccgag
      421 acctcgcgga cgcgcgcgaa gtaggcgtcg acggcctgcc gaccctcagg aaaagtgtcg
      481 tgcaggaggg cgcggaaggc ctgcgggttg tcggggaagc cgagctgcag gccgtccggg
      541 aaggcgaagg cgtcgtagac cgggcccagc gaggcccact gcaggcgacg cccggtgagg
      601 ccggcgagca gccgcccggg catgctgcgc tcggtgacct cgccgacggc gtggacgccg
      661 acgtcccagt ggtacttgcc gcgcttgaag ctgtgggtga agccgcccgg gacgtagtgc
      721 tgctcgagca cgaggacccg ctggccgagc gcggcgagca gcgcggcgca ggtcatgccg
      781 cccatgccgg agccgatgac gatgctgtcc cagaggacag gcgcggcgaa gccggacggg
      841 aggttcttcg accaggggtg acgcacaggg cggtcggaca tgcgtgccca gcatacagcg
      901 cgcggcggcc gcggagcggt ggcggtgcaa aacagcggtc gaggccgccg cggccgcaga
      961 tcgaccgagg cgcggagcgg gacgccggcg cccgtggcga cgccggcgag cacgacggta
     1021 cgaggccgcg aaggggggcc tgtgtgggcg atcgcgcgat cacgagggcg cggcggagct
     1081 ttcggtccca cgctcgaggc gaaggaggct acacacgatg actccgctcg tcctgttgct
     1141 cctgctgttc ctcggcttcg gcctgttcgg agtgctcagc gaccgtgcct gtcgcgccga
     1201 gtcgctccgc cgcggacgcg aggagcgccg cgtgacgctc aaggacttcg tggtgccggt
     1261 ggtgccggtg cgacaccgct ggctgcggcc gcgggtccat cgcggctgag ggcgtcaagg
     1321 gaggcagctg tgctcgaccg acgcgcgaga gcatcggcct cgagctgcaa acgccgagca
     1381 cgctgcggct cacgcttgag ggcggtcagg caacgcgaca gcaggcgtgc gacgtccatg
     1441 cgcacgtatc gatcggcgtc gtcggtttca gtcaggcggc gcgcttcttc gagatgcggg
     1501 agggcgatct ccggttgccg attctccaaa tgataagagg cgaggccgta gaggacaaag
     1561 gccctgtgtt cggggtgttc gggcggatta ttggtataga gcgcgttcag gcgtgagaaa
     1621 tagccgaatc cttcgccaca gcgttgcagc tcgcagagag cggcgcccag gctgtagagt
     1681 agcgcctcca gatcgagctc cacgcggcca tcatcgtgcc aggtaaggag agctcggtag
     1741 acctccaccg atgtggaggg ttgatgggcc tcgaggaata tgtcgcttag cagggccagg
     1801 gcctcgacac gcagttggtg ctgcgcgggc acggatgact ctggatatcc gaggaccgtt
     1861 cgggcccggg ccgtcgccag tgcgaactga cgctcggcga aatcgatatg ggcgagctcg
     1921 agttcgactc gcgcgaggag gatggtgtcc ggaccgtagg ttcgcagcaa gatcggtcga
     1981 gcatccgcaa agcaactgcg tgccggcccc gtctggtcga gctcggcgag gagctgggcc
     2041 tcggcgagct cgacccgcac gacggccgga tgctcgcggc cgaaaatctc gagtgcgtct
     2101 cgcttgagct cgtcgaacag cttcatggcc agctccggct cgcccgcgtt cgcggtcgcg
     2161 ttggcgaggc gcaggccggc ccagatcagc tcaggatggc gggcgtcgag aaaatcgcgg
     2221 cgcagctcgt aggcttctcg atgacgtgag agcgcctcaa ggttctgatc ctccagaaac
     2281 aggatatgac catcggtatc caggagatcg gcgcggtcgt tgggagtgag acgagcatgg
     2341 cgggtcgcgg cagcgcgggc gtattcgagg tactggcgcg ctcgttctcc gtcctgttcg
     2401 actcgtgccg cgaagacagc gagatcgttc cagacccgcc aggccaagcc gtcgagggcc
     2461 gatcccgtgg ccagtacgcc ggcggcgtgc aggtgttgga ggccgccgcg cacgtcgccg
     2521 agatggtggc cgagcaggac gccgcgcagg cgcaaggcgt ctgcttccag cagcggatcg
     2581 ccgacagctc ggatcgccgc gagggcggcg tctacctgcg cgagcgcttc gactcccagc
     2641 ctggccgcgt gaaggctcgt ggcgtgggcc agcgcggcct ctgcgggcgc gaggcgtgga
     2701 tcgcgagggc gcttgtagga cccatcgagg agagcctcgc ggtcgcggca aacacggata
     2761 tcgggcagcc ggtggacgag ctccgggaca gaggcgacca gggcggcgtc cgcatgacgg
     2821 agctgttcga tcagagcatc cagggcgctt cgccggtgcg cgagacagag ctcgctacgc
     2881 tcgaagagca gcagtgcttg ttcgttgcgg ccctgtatct cctcgcagac ttggacgtgg
     2941 gcgtcgagcc actcctcgac atacgcatcg aggcgactct ggacgaaatc ggcggtttgg
     3001 agggagaatg gctgcgctgt ggcgaggatg gccgtgcgga ctgctgcttt cgtttgaaag
     3061 tcccagatgc cttcgagctg gtccctgggc tcggggcaga ggccggggga aaatgcgtcg
     3121 aacggtatga tcgcggccgc aatgaggccg ccggtgagga gcagcacgag cggaaggagg
     3181 agcgagcgga ccagtcggaa ggattgcttc tcgagggcac cgagcagcac gtccatcgag
     3241 gtgaagcgat cggcagggcg cacggcgagg ccgcgggcga ggaggcggcg cagcgccctc
     3301 gggatccgtc tttgcccggc gccggccgga agctcgatcg ctcggtaggc cagctcacgc
     3361 ccgggaacgc tccggggtcc gaaggggcgg tcgccgtaga ggcactcatg cagggcgacg
     3421 cagaaggaga actggtcgct gctggcgtcc acacggccgg tgctgaaggc ctcgggggcc
     3481 atatacgccg gggttcctgc gactgtgccg gtatcggtgg cgcgggcgcc gggatcggtg
     3541 gtcgaacccg agagctcggc gatcgtcggc gagtcgactg ccgcggcgcc gcgagcgagg
     3601 ccgaagtcga cgatccggac gcgtccgtcg tcgccgacca aaatgtttcc gggcttgacg
     3661 tcgcggtgca cgatgccggc ccggtgcgcc gctgccagac ctcgcgcggc ggcgacgaag
     3721 acgtcgacga tcgcggcgac gtcacggggc tcggtccgca gccactgtga cagcgtcgta
     3781 ccggcgacgt actccatgac gaggcagacg gcctcgccgg cagtgacgac ctcgtggagc
     3841 tggacgacgt tggggtgcga gagacgcgcg agcgcccggg cctcgtggag gaggcgccgg
     3901 cgatcggcgt ccgagacgag gacgtcgtcc cggatcatct tcaatgcgac gacgcggccg
     3961 agggtgtcgt cctcggccgc gtagacgacg cccatgccac cgaccccgag cgagcgcagg
     4021 atccggaatc gtccgagctg catcggcgcg gtgtcctcgc cgaagaggcg agcgccgatc
     4081 ctccgtcgca tcgcctcggc gtcgagcgga cgagttcggg cgagctgcgg gagggtcgac
     4141 gcgatgtctt cggtcgggag cggtggaaac atcgaagatc aggagtcttt gctctcgagg
     4201 tccctgtcac cgatgcgggt cttgcgaatc ttgactgtga tcttggtgcc ggtaggtttc
     4261 gtaccatcaa agaagcaaag gcgccacgcg tgctcttgcc cgagcggagg atgagtgaag
     4321 aagaccaaga ttgttccatg tcccaattcg acccaccccg atccctcgac cggggtgatt
     4381 tgcagacttt tcgcctgctg tgcatgttct ggcgcgacag gctcgagctt cacagccgat
     4441 acacgggcgc cggcgacatc gaaagatctc tcgacgtacc cgcccttatc gtatcttatg
     4501 gtgggaagct cgcctgcagg caaatcttca tatctatcca cggtggtcga ggtcgagtcg
     4561 ttcatgtgtc ctccgtctgg ttgggtgtac ttggggtagt gtcgccggtt tcgggatccg
     4621 ttagcgactt cgcgaggtcg tgctaacttt gtacggatgg cgagcgatat cgagctgttt
     4681 cgggcctggc gtgctggcga gcgtcaggcg ggtagcgttt tgttcgcgcg gcacttcgac
     4741 tcgatctacc ggttcttccg caacaaggtc gacggggagg tcgaggacct cgtccagcgg
     4801 accttcgtcg cttgcgtgga ggggcgggag aggttccggg aggagtcctc atttcggacg
     4861 tatctgttcg cggtcgcgca caacctgctg cgagaccatc tgcgccggaa gaagcgggcc
     4921 gcggagcagc tcgacctcga ggaggtctcg gtggtcgacc tcggggcgtc gccgctgtcc
     4981 ttcctggccg cgcatgccga ggagcgggtg ctgctgcacg cgttgcggcg gatccccgtc
     5041 gcgtcgcaga tcatcctcga gctttatttc tgggagcaga tgacggggcc ggagatcggc
     5101 gcgttcctcg gggtcatcga ggacaccgcg cgcagccgga tccgccgggc caagctgcag
     5161 ctcgaggcga tgatccgcac cctcgaggcc acgcccgccg agctcgagag cacgctgtcg
     5221 aacctcgacg gctgggccga ggcgatccgt cgtcaactcg cgccgacctg agccggcgag
     5281 ccgccgtcgg tccgggctgg ctttctttca gcggtgagac gccattcgca ccggagcgag
     5341 tcgagcgctc gctccggatc gcggatgcgg acatgcgcgc tgggaggcgg ctcgacccac
     5401 acacatgcgc tgcgaggtcg ccttcgtcag gcagagaggc tcgacgtggg acctcgcggt
     5461 ggcgctcagc cgggcgggac gaccacgccg caggcgcact tgatcgagac ctggacctcg
     5521 ccgttctgga tggcgtcgca ggcgtcgccg accagctcga cctcgccggg gttgttgagc
     5581 tgccagccgt cctcgtcgcc gaaggggacg accatgccgt tgacgtagac ggtgcactgg
     5641 tcctcgccgc cctcggagac ggtgccgtcg agggtgagct tgcagtcgcg gacgccgtcg
     5701 acgatgtcgg cgaacgcgtc ggccagcgcc tgcgcgtcgt cggccttgta gaacggcgcg
     5761 tcggggtcgc cggggccgac gccggcgccg gcgttggcga cgtcctgcag gtgctggtcg
     5821 ctgacctcgt tgccgacgct gatcacgtag gtgcgcacgc cctgggcgaa cgcggcggcg
     5881 gcggcctcga ccgactcctc ctggccgttc tgcgggttgg gctcggcgca ggtgtcgggc
     5941 tcgccgtcgg tggcgaggac gatgatcttg ttgccctcgg tcgggtccat gaccagcgtc
     6001 ggcgtgaccg cggcgatcga ttcgccggtc ggggtctcgt cctcgggctg gctggcgtcc
     6061 cagctggcgg cgatcgcctg gtagttgtcg agcgccggcg gggtctcggt gatgacgggg
     6121 cactcgccgc cctggtcgcc ctcgaagctg gtgtagagcg ccatgccgaa gcggacctgg
     6181 ccctcgaggt gggggacgag gccgtcgtcc tcgtcgagca aggcgttgta gacggcctcc
     6241 cagcggtcgg tgttgccgaa ctgggtggtc atgctgcccg attgatcgat gagcagcagg
     6301 acggtgggga tctgcggctc gaaggtcacg tcggcgtcgg cacacacgct ggtgtcgctg
     6361 gcgccctcgc tgtcggtcgc gctgccggga ccgcccccga ggtcgaactt gacggcctcg
     6421 tcggtggtcg aaccagtggt cggcccggtc tcggtcgcgc cggcgctgac gctggtgacc
     6481 ccgggaatgc cggtggtgct gctgccggta tccgtgtcgg tcccgggagt gccaccgacg
     6541 ccgccgcagc cggccatcac cgcgaccatt gcccacattg tcccgcatga atggttaatt
     6601 cgcgcaagca tcagtgcaag catagtgagg tcgaccgggc gcgctagccg gattgtacct
     6661 gccgctttcc tcgtcctccg gacggggttc atggaccctc gctcgagatc gatacctgcg
     6721 agcgcgcgta tagcccgcag ctccgcgcgc agatcatgcc acactgcgct gcatcgacgg
     6781 cgcggcggag gattgctcga tcgcggcaaa aatcgccgtc tcgcggcgtt ctcgggccgt
     6841 ctcggcgcgg ccgcgaccgg cgacgcgccg gggcgagcgc gagcgacgag gcgctcgcgc
     6901 gtccgcgacg gcggggtcgg ggattcgtcc tgtcgcgcgc gaccgacaag caatgcggcg
     6961 aggcggcgac gcatcgcggt ggtgcgcgga ttgctgtcga tcgtcgcgcc gaagcgccgc
     7021 gacgggcgat ctaccaccgt tcgatggtga gggcgcgaat tgatattcca ggtcgagaag
     7081 ggtcttttat ggcgaccgat cgcgcagcga ggcccgctag ccgcggtcgc gcagggcctt
     7141 gcggtggatc agccgcgcca gcgggccgcg cggcgggacg gaccacagcg gctcctcggc
     7201 ggcgccatgg tggtgaagaa tgtgattggc ggcgaggatg cccgtgctgg cggcgcgctc
     7261 catgagggcc gtggggaacg gagtgtggat gcagtcgccg gcgaggtaga gggtcgggtc
     7321 cggggtgtcg acgcgcaggc gcagggggtg ggtgccgggg cggaaggcgg ggcagtcctg
     7381 gctcaggagg aagcgctcgt cgagcgtggc ggcgtcgcgg gtctcggggt agaggtcgtg
     7441 gagggcgcgc agcaggtcgg ccttgatctc ggcctcgtcg agctcgtcgg ggagggcgta
     7501 ggcgtgcagc tcgacgacgc tgccgccgct gcgcgcggcc cagtcgcggc tctcgtcctc
     7561 gaacaacggg tagagcgaga tgttgtcgac gaggccgagg ccggtggtgc cgacgaacgc
     7621 ggcgcggcca ggcgcgggcg gccgatcgag ccacaacctc cacaccgcga agcgagcggt
     7681 gacggtctgg gcggcgacct gctcgcgcca gcagtggccg atgcaaggat cctcgggggc
     7741 gacgcctcgc gggtagccga gatgcggcga ctcggcgacg agctgctgca ggccggggac
     7801 gctggcggcg aggatgcagg cgtcggcgtg atagacctgt cctctggagc tggtgacgcg
     7861 atggcgaccg tccggcccgc ggtcgaagtt gacggcggcc tcggcgaggc gcaagcggac
     7921 gccgcggcgc tcgagcacgg ccgccatcgg ccgccagagc gtggtcgaga acgggccgcg
     7981 ggcgacgtcg aagacgatgc cctccgggtt gccgacgaag tagaagtgaa acatcatcag
     8041 cagctcggcg gcgctgaact cctgctcggg gttgaagaag gagtgggcga agacatcgaa
     8101 cagcatctgc cgggcgcgcg gcgggaagcc gaggcggtcg aggaagctgc gcgcgtcctc
     8161 gcggtcgaac tgggcgtagg tggcgagcgg gtcgtaggcc atgatcgcgc gcccgcaggt
     8221 gtcgtcgacc cgcaaggcgt cgcgccaggt catggtgctg ctgcgccgga tcaggctgac
     8281 gaggttccag atcggcagct tcggcaggcc cgcgaacgac tcgcgcaggc cgtcggggcc
     8341 gagcagcggg tagtcctcga ccgggcgcaa gaagccgagc tccggatcga tccgccgcag
     8401 ccactcgcgc aaattgtagt actggcggaa gaaggcgtga aagccccgct ccatctcgaa
     8461 ctcggtgccg tcggcgaggg tgtccgtcca cgcgccggcg cgaccgccca ggtaggtctc
     8521 gggctcgagc accgtgacgc gggcgccccg ctccgcgagg atcgtggccg ccgcgagccc
     8581 ggcgatcccg ccgccgacga cgaggacgtc gagcggccgc ggcagggcga ccggcgcgcg
     8641 ccggtcaggg gtgttggcag gtcggcggga gattcccagc atggtgttta tttaaaaaag
     8701 aagggtgagg cgcgcggatg gcggatgtcc cgggggacag gttcggcgaa agggtggaga
     8761 tgtccttggg gacaggcgaa tggccgcggg ggcgaaggat gtccttgggg acaggtagga
     8821 aggtgagccg ccgcgggcgc agggaggatg tcccggggga caggtggtgc gcggcgtcgg
     8881 cgtcggcgcg cctcgcggct ccttcaggta tggctcaggc cgggcggcgg gccaggaagg
     8941 tgtggacgat gccctcctgc cagccgtcca tggtggccga ctgggtgtcg cagaagccgg
     9001 ccgcttgcag gcggcgcagg aaggcggcgg cgccgtcgaa ggcgttcacg ctgcggcgca
     9061 ggtagcggta gatgttcgag cccggcgagg tgacgaggcc ggcggggatg atgatgccga
     9121 ggcacaccgc gttccacacc aggtgggccc gcagcgagtc gcgcacgctg tactcgtgga
     9181 agcagatcac gccgccgggc ttgaggagcg ggagcagccg ccgcagacac aggtccgggt
     9241 cgggcatgtt gcggatcccg taggccatca ggatgccgtc gaacggcccg ctcgcgccgt
     9301 acgccgccgg gtccatggcg tcgccctgca ggaagcggac gccggtgagc tcgcgcttct
     9361 tgcgggccag gtcgagcatg cccaccgagg cgtcgaggcc ggtgatccgc gcgcgcggat
     9421 aggtgcgcac gagcgcgagg gtggataaac ctgtcccaca gcacaggtcc aaaagggcag
     9481 catcctccgg gacccgcatg cgctcggcgc tgcgctcgag gtgccggtgg tagccggggt
     9541 tcatgccggt gaggaggtcg tagcgggccg cgacgcggtc gaaggcgtgc gggacggcct
     9601 gcttctgcgc gcgcagggac ggcggcggtc gagtcatggc ttggatcggg tgaggacgag
     9661 ccgggcgatc ggcccgtggt ggagagagtc tgcgcgagga tcgagctcga gcgagggcga
     9721 atcgcggcga gacgatcgag gcatcgcagc ctcgccggga gcgggtggcc ggaatgcagg
     9781 tgcgggtgtg aggcgcgccc ggaggcgacg tttgggcggc ccgcgacggg cattcgggcc
     9841 ccgagaggcg ctcgaatgcg gggctcggcg ccggcgcgac ggagagcgag ggaccgcggg
     9901 cctcgcgggg catacgaggg cttgtgcagg gcggctgcgg acgaatcgct cgcgggcgcg
     9961 tggatgggcc atgcgagccg ctcctttggc ctcgccgacg tcacgagcgg aggctggcgg
    10021 cgagcggcgg gggggcggcg aggagctgct cggaccagcg gcggaggtgg gcgaggaggt
    10081 cgttgcggcc ggcgcaggtg gggatccgtc cggcggcctg gtcgacgagc tcgccgaggt
    10141 ggagggtggc gccgctgagc ccgagctcgc ggacggccga gggccggtga tgggtgcggt
    10201 cctggccgac cggcttgccg agcagctcgg gccggccgta ggcgtcgcgg atgtcgtcgg
    10261 cgatctggta ggcctcgccc aggcgatagc cgaggccggt ccactgcaag gggtcgccgc
    10321 cgcctgtcat ggccccggcg atcacggcgg cctcgaacag ggcgcccgtc ttggcccggt
    10381 gatagcggcc gaggtcgtcg aggccgacct cggactccca cccctggccg gcgacgatgc
    10441 ccgcaggccc gccgacgccg cgcgcgacca cccgcaagag gccgggcaag aggtgcgggt
    10501 gcggcccgcc ggcccgcgcg agggtctcga aggcgaggac gatcagggcg ttgccggcga
    10561 ggatcgccag ctcctcgccg aatgcggcgt ggacggtggc gtggccgcgc cggacggcgg
    10621 cgtcgtcgaa acacggcaaa tcgtcgtaga ccagcgaggc gcagtgcagc agctcgactg
    10681 cggccgccgc cgcatccacc agcgcaggat gcgcgtcccc gcacgcctcg gccaccgcca
    10741 ggcagaactc ggggcgaaat cgcgcgccgc ccgggaagac cgcgtggcgc atggcctccc
    10801 cgaggcgcgg gggacagggc gctgcggtcg cctggtcgag gcagctcttg agggctcggt
    10861 cgatgcgccg tcgcgaatcc atgactgctc tcaggcccgc ccgggccgcc gatacaacaa
    10921 agataggcgc aaaagtgtgc ctgcgtgttc aagcattgtc aatgaatcga gctgatcgtt
    10981 ggacaaagac ttgaaacctg gagtggtcgc gataatttgg cgacagtcat ggtggtggcg
    11041 aagcagagcc cccgcgtggt ggtggtcggt ggcggggccg gaggtctggc ggcggccgtg
    11101 gactgtgccc gccgcggggc gaccgtggtg ctgctcgagc gcggcgcgga ggtcggcggc
    11161 aaggtgcgcc aggagtgggt cggaggccag tcgatcgacg ccgggcccac ggtgctgacg
    11221 atgcgctggg tgttcgaggg gctgttcgcc gacgcgggcg cggctctggc ggagcacgtg
    11281 caactgcaag cattgacggt gctggcgcgc cacgcgtggc aagacggcga gcggctcgac
    11341 ctgtacgccg accgcgaggc cacggcggcg gccatcaccc gcttcgcctc ggcggccgac
    11401 gcctccgggt acctcgcgtt ctgccgccac acagaggcga tctaccagaa agtccagggt
    11461 ccgttcatcc gcacggcgca gccgacgttg gcgaccctgg tcggctcgct cggcctccgc
    11521 gggctgccgg gcgccctcgg cctcgacttc caccggacga tgtggaaggc cctcggcgat
    11581 ttcttccagg atccgcggct gcgccagctg ttcgcccgct acgcgacgta ttacggctca
    11641 agcccgttcg aggccccggc cacgctcaac ctgatcgccc acgtcgagca ggctggagtg
    11701 tgggcccccg cgggcgggat gtcggcgctg actcgggcga tcgccgagct ggcccgccgc
    11761 cacggggcgg agatccgctg cggggccgag gtcgcggcga tcgaggccga cgaccgggtc
    11821 cgggcggtcc gcctgacgtc cggggagcgg ctgccggccg acgcggtgat cttcgccggc
    11881 gacctggcag ccctggccgg cggcctgctc ggcgcggctc cggcgcgggc cgtgaagacg
    11941 cccccgaagt cgcgacgctc gctgtcggcg atgacgtggt gcctgcgcgg cacggccggc
    12001 ggctggccgc tggcgtatca caacgtactg ttctcgcggg actacgcggc cgaattcacg
    12061 gcgctgatgg accgcagggc gctcccggcc gagcccacgg tctacgtctg cgcgccggat
    12121 cgccgcggcg gtcccccacc ggccgcggcg gagcgcctgt tcgtcctggt gaacgcgccg
    12181 ccccgcggcg gcgaagggtg gctcacggcg agggagatcg aggcatgcga acgagcgaca
    12241 tggcgagtga tcgagcgctg cgggctgtcg atggcgccgg cggagccgcc gcgggtgacg
    12301 acgcccgacg acttcgcggc gaggttcccc ggctcgggcg gggggctgta cgggacggcg
    12361 acgcggggcc tgctggacgc gctggggcgg ccgacggcgg cgacgaagct gccggggctc
    12421 tacgtggccg ggggcagcgt gcatccgggg gcgggggtgc cgatggcgac gctgagcggg
    12481 cggttcgccg cggcgacggc gtgcgcgggc ctctgttcga ccgggtggtc cctccgggcg
    12541 gctacggctg gtggtacatc gacgcgctca gcgacgacgg cgcccacggg ctgacgatca
    12601 tcgccttcgt cggcagcgtg ttctcgccgt actacgccag ggcccgcgcc agagcccccg
    12661 ccggcgcggc cgacccgatg gcccactgcg cgatcaacgt ggcgctctac gggcccggcg
    12721 tggacgcgtg ggtgttcacc gagtacggcg ccagcgaggt cgagcgccgg ccggagcagc
    12781 tgcaggtcgg cggcagctcg ctgacctggg agggcgactg cctggtggtc cgcttcgacg
    12841 agcgcacggc ggtgctcggc cagcgggtgg ccgggacggt gcgcctgtac ccgtcggcgt
    12901 tccccgaccg cccggagccg atcgacgccc acggccgcca cacgtggttc cccgcggccc
    12961 cgcacgcgca cgtggtggcc gagctgacgg cgccggcgct gaccctgcgc gggaccggct
    13021 accacgacgc gaacttcggc gacgagccgc tcgaggcggg cttcgtcgag tggagctggt
    13081 cgcgcgcggc gctgtccgac cgcaccgtgg tgctgtacga cgcccaccgc tgcgacggca
    13141 gccagctgca gctcgggcgg gtgttccacg ccgacggccg ggtcgagccg ctggccgccg
    13201 cgcacgcgat gaagctcggc cgcacgcgct ggtggatcgc ccgctccacc cggaccgacg
    13261 gcgcccccgc cacggtgatc cgcacgctcg aggacacgcc gttctatgcg cgcacccagg
    13321 tggccacccg cgtcggcgag gtgccggtgc gcgcggtcca cgagtcgctg tcgctgtcgc
    13381 gcttctgctc gccgctggtg cagacgatgc tgccgttccg gatccgccgg gtgagctgaa
    13441 gtacatgttt taaggataat gcccgatcgg gcatgttcga tggttcatgt ccgagagagc
    13501 atgtccgatc ggcggcggag cgggcgcagg ccgaccaggg cggcgacgac cacggcgacg
    13561 ccggcgaccg cggggaacat cagggcggcg aagtagggga agaagtagac ggtgggcgag
    13621 gggaccggga agccgaggtg ccagccgagc accagcgggt gggccgcgga gagcaccgcg
    13681 ccggccagca agatcgccgc gaggtcgagc atcagggcgc agcgatcgcg gcgcaccagc
    13741 cagtggacca gcgcggcgag gctggtccag ccgaggccga gagtgagggt gaagccgatg
    13801 aactcgccgc ggcccgcgac cgagctgagg tcgaagctgc cgcgcaggcc gacctgcagg
    13861 gcgtaggtga cggccccgaa caccgccacg aagccgaggc cgaacagcgc ggcgctgcgg
    13921 gcctcgccct gccgctcgcg gcggcggtgg aggtggagct gcagcaggaa caccagcgcc
    13981 agggcggcga ccaggacccg ggcgccgcgg cggtggccgg cccggtgggc ctcgtagaag
    14041 gcgtcccagc tgccgtcgct gtccggcagc cacgcgcgca cggccgcctc gttggcccgg
    14101 cggaaccgct cgacggcggc gcggcgatcc tcgaaatacg cgggcgggaa ggcggcgggg
    14161 tcgacgaggt cccacagggc gtcgaggtcg tcgtcgccgg cgcgcatgtg ggccgggaac
    14221 ggcaggccga gcagcagcgc cagcgagggc gcgactgtgg tgatttgcaa atggccgtac
    14281 tcggggtcgc ggcgcacgcc gaggccggcg tggcaggtca tgacattggc gatcggctcc
    14341 tgcgcgccgc cgtggccgcc gcgcggcgag tgcccgtggt cggcggtgag gatcacgagg
    14401 tcccgcgaga agtcgacggt gcgcaagaag ccggtgagct cgcggtcgac ccgcgcgacc
    14461 gcctcggcgt actcgcgcga ggcggccccg aactcgtggc cggcctcgtc gacgtagagc
    14521 gggtggacca gctggaggtc ggccggcggg accgcggcga agtagtcgac gtcgaggggg
    14581 aggacgtcgt agctggtgaa ggcgccgggg aacagctcgc gccaccaggt cagctcgctg
    14641 acggcggcga ccgacaggcc ggcgccgcgg gccaggctcc acacggactg ggcgaacagg
    14701 ggcgactcgt cgtcgttgcc gcgggcgccg gtgcggtcct gctcgaggcc ggtggagatc
    14761 gtcgcgtaga ccggtcgcga catcgacggc acgccgacgg cggtcttgcg gcactggccg
    14821 tgctcgcgca ggagcgcgat cgcgcccatg gtcctggcgg cctcgtgccc gagcccgtcg
    14881 accaccacga ggacgctgcg gcgcggtcta cgcggctccg cgtccggcgc gatcgcgtcc
    14941 tcgacctgca ccgcgaagaa gccggtggcg tgcgacgaca gccgcgcgga gtaggtgact
    15001 cccagcagca gcgggacgcc caggccgagc gcgctgcagg cgaggaggag caccaggcat
    15061 tgccggacgg tcatgtctca gttagagcat ggaccgtgcg gagcgcccac gcgaatgccg
    15121 acgatcgaag ggaaccgccg acgaccgccg cgcggcgatt gctggcaccg ctcgtcgcgg
    15181 cgatcacggc ctgcgcgccg acgtggaagg cgccgctgac ggtcgacagc cgcgaggtcg
    15241 cgcgcgccct caacgacccg gccgacgtcg tgaccgactt cgacccggcc gcggtgccgg
    15301 tgttcgaccc gccgaagaag ctccggccgt gctgcgcctt cggccaggat ctgcgggcgg
    15361 aggtcgggcc ggtgccggtg ccgctctaca agaacgagaa catccgctcg ccggaggaga
    15421 tcgggccgca cggctacgac aagggcgagc tgacgcgcga gcgcaacggg ctggtgtaca
    15481 cctgccgcgg cggcttcctc gacatcgccc acgtgcgcga caccgccgac cgcacgctct
    15541 tcctgacgct gcagctggtg cgacgattgc cggagggggc gaccgtcgaa tggcccgagg
    15601 agggcacgaa gcggcgggtg gtggtgaagc cgctgccgcc cggcctgctc gagcgccacg
    15661 gccggtggaa gacggcgacg gcgctggcga gctgggcggt ctatcaattg tcgacgtggc
    15721 acgaggtggt cacgtggtac ggcttcgaga gcgtgccggg ggtgtcggag cggctgtcgt
    15781 cgttctcgcc ggaggacgtg tactcgaacg tgctcggcat caacctcgcg gccgggctca
    15841 tcctcgacgg ggagatccgc tcgcgcgagg agtacgacgt ggcgatgcag gcgtggatcc
    15901 gcgaggccct gcgccgcctc ggcgcggtgc ccaaggacaa ggcgcgggcg gcgatgcagg
    15961 cggtcgacgg cctgtggtgg gactcgagca agcgcgtgcc ggagttcact ctggtgacgc
    16021 gtcgctatat ccataccgat tcgccgatcc cggcctggct ggtccgcgac cccgccgtcc
    16081 gcgagggctg cgccggccag ccgcccccgc tcccgctggt catcgaccac cgcctcggcg
    16141 accgcgagat ctccgagctg gcgagcgtcg agttcgagtt cggcaagtgg cggccgaaga
    16201 atttccccat gccgctcgcc gagggcacga cggtgaccca ggccgacttc ccgaccatca
    16261 ccgccgacat ccgccacgag ggcgcggcgg tgttcggccc cgatttcgac cagcccggcg
    16321 aggcgcaggc cgaccggccg gacgcgaagg aaaaaattgt gcatcgagcc gtgacggatc
    16381 ggcgacggcg ggcgactacc tccgcgggac cgtgatgccg gagtcgcgcc ggcagcacgc
    16441 acactatcct cgcgacgtat ccctccccgg tcgccccggt tcgccgcttc aggccctcac
    16501 caggctttga agcctttttt aattcggcgg caggccgggc tggagggcct cgacccggcc
    16561 ccgcagcagg gcctagcggc ccaggggctg cgaacctgcg aggtcgaccc ggtgccgttc
    16621 tgcgcgttgc gcacggagcg accgagcgac gagtcgaggg gctgtctctg gcacgcggcc
    16681 gtcgcgggcg agcgggtcga gggggggctt gtggcctgtc ccgaagacca gaatcatcgg
    16741 gcggaccgaa gaggccgtgc gcagcgaggc ccggtaggcc ttgggtcggg agcggtctcg
    16801 caacaaaggc gggggagatc tccggcgagg atcttttcgc gctcgcggag cgcggtgcag
    16861 aagatctgca aggtcgctcg gcatcggcga ggtccgctcg gggcctggaa ccactcagag
    16921 cgccgcggcc gcagcccggg cgcgtcgatc cggccggcat caccgctttt taaaagggcg
    16981 ggctccggcg gggcgtcggg tatcctcgcg gcacaggccc atggacgcgc cgcgcgagcc
    17041 cggatccgag caggtgtttg ataagacagg gctcttgggg catgtcgcga tgggcatggc
    17101 cgttgggaca tgtcttttgg ggctggccat cccgcggctg gcggaggcgc accaggtcgg
    17161 gctgtcgcgc ggggtctaca cggtcgacgg ggcggtggtc gagggcgatt tgacgttcgc
    17221 gcggggcgag ctgcgggcgc tggcgccggg gctcgacggc gacggggacg ggacgctgag
    17281 cgaggccgaa gtggcggcgg ggggcgcggc gctggctccg gtggtcgcgg ggatcggtgt
    17341 ggcgagcgac ggcgaggcgt gcgtcgggac gctgacgcgg gcgtcgctga cggaggagga
    17401 cggggcttcg ctggcgatcc gcttcgcctg tccgcagccg ccagagtcgc tgacgctgac
    17461 gtggtcgctg ttcgacgcgc tgtcgacggg gcaccggcac ctggggcagt tcgtccgacc
    17521 cggagctggc cccgaggaca tcctcgccga gccggtgctg cacgcgcgcg cgccggcggc
    17581 gaccgtggcg ctcgcgggcg gggaggcgga ggcgccggcg cggccggtgt cggcctactt
    17641 cgagctcggg gtcgagcaca tcctgatcgg gaccgatcac ctggtgttcc tgctcggtct
    17701 ggtggtggtc ggcggccggc tgcgctcgct ggtcgcggtg atcactgcgt tcacgatcgg
    17761 ccactcgctg agcctggcgc tggcgactct ggggatctgg acgccgagcg gggcgtgggt
    17821 cgagccggcg atcgcgctgt cgatcgcgta cgtcggcgtc gaaaatttct tcgtccccga
    17881 cgcggccggg cgctggcgga tcacgctgcc gttcgggttc attcacgggt tcgggttcgc
    17941 cggggtgctg gccgagctcg ggctgccggc cggcgaggtg gcgccggcgc tgctgctgtt
    18001 caacctcggg gtcgaggcgg ggcagctcgc agtgctggcg ctggtgctgc cgctgctcat
    18061 ggcgctcggg cgcttgccgg cgtaccgaca attgcagggc gcgcggtgga tctcgggggc
    18121 catcgtgctc gcggggctgt ggtggttctt cgagcgcgtg ttcggcgggt gagcccgcgg
    18181 ttcgagtcgt gagtgtcggt gcggcgccgg ctcattcgcc gcgccgactg cgagttccgg
    18241 ggggctcatc gtcacgcgcg agggcgagtc gccggcgcgc ttggtcgacg aaggcaccct
    18301 cgatcactgc acctcgtcgg cgatctgcgc gagcagggtg cgaatcgccg cgacgtggcc
    18361 gtcgtgcccc tcggggccga acaccgcgag cgggagctgc ggcgggatcc cgcggccctc
    18421 ccagttctcg ccctgcggat cggtgtagtg ctcgttcgac aggcccacga accagccgtt
    18481 cggcagccgc ttctccagca ccgtcgagaa ggcgccgcgc gtcgactggc cggcgtggcg
    18541 cacgttgggc agggcgcgca gcgcgagggt gaggatctcg ccggcgctga ccgtctcggc
    18601 gctcgtcacc acgtagacgg gcccggtgaa gcggcgaccc ttcgcgggct cgacgcggac
    18661 agcgaagccg cgcgactgcg ggtcgtcggc cgcgcggcgc gtgtaggcca cggccggcgc
    18721 ggcggcgaag cgaccggcga gcgcgagccc gatgaagtcg tagccgccga tgttgaggct
    18781 ggcgtcgacg atcaccgcgc gcgcgttcct ggcctcgaac agcgccagcg cgtcgttcat
    18841 caccgcgtcg agcgtcggca gctccgcgcg cagcgaatcg tagtcgccgt cgacgaagcc
    18901 gcccatgctg accgcggcga gatagccgac gccgcccggc agcatgccgt actggatccg
    18961 ctgattggcc gcgatcgtgc cgccgccggc cagcagctcg cggccgatgc cgtcgagcca
    19021 gtaggtgcgg cggaactcct ggagcgcctg ccgcgggtcg gcgccgcggc gggccgcatc
    19081 ggcggcgagg aagcgctcca gcgggccctc gtcgccgtcg tgcacgtgcg tcgcgccggc
    19141 gaactcggcc tcgatcttga tgtgggagtc ggtcagcggc tgcaccagct cgcgcaagat
    19201 cgcaaacagg gcggcgtcgt cggtcgcgtc gctcacgcgc tcgcgcgccg cggcgacccg
    19261 gctcggccag tcgacgccgt acagcgagaa gaacgcgtag tgatgggcga agaactcggc
    19321 gaacgcggcg aagttggcgg gcggggtgtc ggcggtcggc ggcgtgcagg ccggcggcag
    19381 ggcggtcagg cgggtgaagc ggaactcgta gggatcgagc gcgctcgaca gcaccatcgt
    19441 ggtgccgctc ggctcgaggc ggacctggtc gaagaacggc aagaccgacg cgtcgaggtc
    19501 gcgctgctcg acgcagacgt cgccggcgac gtcgaacagg cgcacgcggc cgcgggccac
    19561 ggtcagcacg tagccgtagc cctgcgactg ccacacgccc gggtggtcgc ggacgacgcg
    19621 ggccgagcgc ggggcggcgc acgccgtgag gattacaacc gcggtgaaca ggagcttcga
    19681 gccggagcgc gtcatggtcg gacccgccgt ctcttaccag aactcgcgcg gctcccggtc
    19741 gcgatgcagc gagctcgctg ccggcgcacc ggcacgcgcg cgctcgtcct gatgcagggg
    19801 cgttgattcg gcgtcgagct cggcggtgca ggggctgcgc ctggatcggc acacctcctg
    19861 cgacgcgctg gacgccggct ggcgtcgcgg cgccgacgaa gcggtcgact tctcgaccag
    19921 gagcgaggcg gcacacgtgt ccttcgggac atctgcgaac acagggagat gccccgagag
    19981 acagacgcgc gcggaggccg gcggcggggc cgcgaggggc gcgccgggtg atgcgggctg
    20041 cgaggatgtg cgcgggcccg acgcccgcgg gcgcgggctt tcgcggcggg gcggggcgcg
    20101 atagggtggc ttcatggcgc tgctgaacct gcccgacggc gagctttatt atgaggtgca
    20161 cggcagcggg ccgccgctcg tgttcgccca cgggctcggg ggcgggtttt tgtcgtggtg
    20221 gcagcaggtg ccgcactttc gcaagcggtt cagctgcgtg gtgttctcgc accgggggtt
    20281 cgcgccgtcg cgcgatgggt cgggacaggg gccgcggagg ttcgtcgacg acctcgacgc
    20341 gctgctgcag cacctgcacg tggacgacgt gcggctggtg gggcagtcga tgggcgggtg
    20401 gagctgcctc ggctacgcgc tgcggcggcc ggagaaggtg cgggcgctgg tgatggcctg
    20461 tacgacggga caggtgacga cgccggagat cgacgcggcg atcaaccggc tgcgcgggcg
    20521 ggcgaccgcg gcgttcatga agggggtgca cccggccgcc ggcgagcgga tggtgcgcga
    20581 ccagccggcg atgcacgagc tctaccgcgg gatggacatc ctcggcggcg cggacaagcg
    20641 ggcgatccgc gacgtcctgc tggggatgcg gacggtgacc gcgcgcgacc tcgagggctt
    20701 cgaggtgccg acgctgtgca tgacgtccga cgaggacttc gtgtgcgcgc cggactcggt
    20761 ggcccacctg gcgcgcatgc tggtcggcgg ccgctttatc aaggtgccgg agaccgggca
    20821 ctcgatctac tgggagcgcc cggcgctgtt caaccagctg gtcgacgagt tcctcgactc
    20881 gg
//
