LOCUS       NZ_JAPTYM010000001     10405 bp    DNA     linear   CON 29-AUG-2024
DEFINITION  Streptomyces noursei strain ATCC 12757
            contig_1_pilon_pilon_pilon_pilon, whole genome shotgun sequence.
ACCESSION   NZ_JAPTYM010000001
VERSION     NZ_JAPTYM010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces noursei
  ORGANISM  Streptomyces noursei
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 10059690)
  AUTHORS   Koduru,L. and Wong,F.T.
  TITLE     Cost-effective hybrid long-short read genome sequencing and assembly
            protocol for GC-rich Streptomyces
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 10059690)
  AUTHORS   Koduru,L. and Wong,F.T.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-DEC-2022) Institute of Molecular and Cell Biology,
            A*STAR, 61 Biopolis Dr, Proteos, Singapore 138673, Singapore
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 03-AUG-2022
            Assembly Method                   :: Flye v. 2.8; Pilon v. 1.24
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 1x
            Sequencing Technology :: Oxford Nanopore GridION; Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_026913165.1-RS_2024_08_29
            Annotation Date                   :: 08/29/2024 08:44:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,375
            CDSs (total)                      :: 9,278
            Genes (coding)                    :: 8,845
            CDSs (with protein)               :: 8,845
            Genes (RNA)                       :: 97
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 433
            CDSs (without protein)            :: 433
            Pseudo Genes (ambiguous residues) :: 0 of 433
            Pseudo Genes (frameshifted)       :: 168 of 433
            Pseudo Genes (incomplete)         :: 311 of 433
            Pseudo Genes (internal stop)      :: 17 of 433
            Pseudo Genes (multiple problems)  :: 60 of 433
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:08:00
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2888068
            Orig. end                         :: 2898473
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAPTYM010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..10405
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ectoine"
                     /region_number="19"
                     /rules="ectoine_synt"
                     /tool="antismash"
     cand_cluster    1..10405
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="ectoine_synt"
                     /kind="single"
                     /product="ectoine"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10405
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:5405](+)"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5405
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
     gene            complement(192..1178)
                     /locus_tag="O1M07_RS12835"
                     /old_locus_tag="O1M07_12830"
     CDS             complement(192..1178)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018536882.1"
                     /locus_tag="O1M07_RS12835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1M07_12830"
                     /product="SCO1860 family LAETG-anchored protein"
                     /protein_id="WP_189857977.1"
                     /transl_table=11
                     /translation="MSTRSTTFAGSTGTTGRIGAVLAAAVLTAGPAVALAAAPAAYATG
                     DDARGHGTSGAVVLRTALDVNLLDKSLNVPVRAVLDEVHAPASADKTALTVRLDGIDGG
                     RPVSLLRADVATARATADGRTTEGHADLVRAKVQLPGLPALPLAEVQQVTARAVCTAGQ
                     RPRAESQVLGDVVVLGKRVALRAGGTTEVDVPGVGDVRLDLSQKSTTSASAAATALQLR
                     VSVNPLKLNVAEVHGQVTLAQATCTTPHGTPDKPGTPAHPGQAHEPGTGTQAHTGGGAR
                     PATENLAETGGSAATPYLVGGAVLLVAGGAGAMVHTRRRSAAPDGRG"
     gene            complement(1443..2534)
                     /locus_tag="O1M07_RS12840"
                     /old_locus_tag="O1M07_12835"
     CDS             complement(1443..2534)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016576771.1"
                     /locus_tag="O1M07_RS12840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1M07_12835"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_189858340.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 1.6e-16, bitscore:
                     59.5, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEGAVLHLKGRVLVGPDDVRDELWVIDGRVSFERPTLARDARTV
                     TGWVLPGLVDAHCHVGLDAHGPVDAATSEKQALTDRDAGTLLIRDAGSPSDTRWIDDRP
                     DLPRIIRAGRHIARTRRYIRNYAHEIEPADLVAYVAQEARRGDGWVKLVGDWIDRSTGD
                     LAACWPPGEVAAAIAEAHRLGARVTAHCFAEESLAPLVEAGIDCIEHATGLTEDTIPLF
                     AERQVAIVPTLVNIATFPQLAAGGEAKFPRWADHMRRLHARRYDTVRAAYDAGVPIFAG
                     TDAGGSLPHGLVADEVAELMKAGLPVEAALSATTWGAREWLGRPGLTEGASADLVVYEA
                     DPRADVRVLAAPRLVVLRGRVVG"
     misc_feature    2837..2851
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.87"
                     /tool="antismash"
     misc_feature    complement(2861..2876)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.62"
                     /tool="antismash"
     misc_feature    complement(2871..2886)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.52"
                     /tool="antismash"
     misc_feature    2924..2936
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 16.37"
                     /tool="antismash"
     misc_feature    3005..3017
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.04"
                     /tool="antismash"
     misc_feature    3028..3042
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.04"
                     /tool="antismash"
     gene            3042..3608
                     /gene="ectA"
                     /locus_tag="O1M07_RS12845"
                     /old_locus_tag="O1M07_12840"
     CDS             3042..3608
                     /EC_number="2.3.1.178"
                     /GO_function="GO:0033816 - diaminobutyrate
                     acetyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0019491 - ectoine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ectA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018536877.1"
                     /locus_tag="O1M07_RS12845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1M07_12840"
                     /product="diaminobutyrate acetyltransferase"
                     /protein_id="WP_189857979.1"
                     /transl_table=11
                     /translation="MTAAQADHAGARSEIREIPEGFKLDTPRVEDGAAIWRIARDSKTL
                     DLNSSYSYLLWCRDFAATSAVARDATGEPAAFITGYLRPDRPDTLVVWQVAVDAAHRGR
                     GLAAALLDGLTTRAADELGVRRVETTVSPGNTASNRLFASFAERHSVPIEREVLFDAAL
                     FPEQGHEAEVLHLIGPFEAPPGGRR"
     gene            3677..4945
                     /gene="ectB"
                     /locus_tag="O1M07_RS12850"
                     /old_locus_tag="O1M07_12845"
     CDS             3677..4945
                     /EC_number="2.6.1.76"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_function="GO:0047307 - diaminobutyrate-pyruvate
                     transaminase activity [Evidence IEA]"
                     /GO_process="GO:0019491 - ectoine biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (28-365). E-value: 4.2e-74.
                     Score: 241.5. Matches aSDomain:
                     nrpspksdomains_O1M07_RS12850_Aminotran_3.1"
                     /codon_start=1
                     /gene="ectB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007448159.1"
                     /locus_tag="O1M07_RS12850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1M07_12845"
                     /product="diaminobutyrate--2-oxoglutarate transaminase"
                     /protein_id="WP_189857981.1"
                     /sec_met_domain="Aminotran_3 (E-value: 4.4e-76, bitscore:
                     255.1, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLTQPDLSVFETVESEVRSYCRGWPTVFDRAQGSRLTDEDGHTY
                     LDFFAGAGSLNYGHNNAVLKRALLDYIERDGITHGLDMSTTAKRAFLESFQNIILRPRD
                     LPYKVMFPGPTGANSVEAALKLARKVKGRESIVSFTNAFHGMSLGALAVTGNSMKRAGA
                     GIPLVHGTPMPFDNYLDGQTPDFLWFERLLEDQGSGLNKPAAVIVETVQGEGGINVART
                     EWLRALAALCQRQDMLLIVDDIQMGCGRTGAFFSFEEAGIVPDIVTVSKSISGYGLPMA
                     LTLFKPELDIWEPGEHNGTFRGNNPAFVTAAAALDTYWADGQMEKQTLARGEIVEAHLK
                     AIAEEHPGTFAEYRGRGLVWGLECTDKSLANKIAGRAFELGLLIETSGPESEVVKLLPA
                     LTTTPEELDEGLRILARAVRDCA"
     aSDomain        3761..4771
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_O1M07_RS12850_Aminotran_3.1"
                     /evalue="4.20E-74"
                     /label="O1M07_RS12850_Aminotran_3.1"
                     /locus_tag="O1M07_RS12850"
                     /protein_end="365"
                     /protein_start="28"
                     /score="241.5"
                     /tool="antismash"
                     /translation="FDRAQGSRLTDEDGHTYLDFFAGAGSLNYGHNNAVLKRALLDYIE
                     RDGITHGLDMSTTAKRAFLESFQNIILRPRDLPYKVMFPGPTGANSVEAALKLARKVKG
                     RESIVSFTNAFHGMSLGALAVTGNSMKRAGAGIPLVHGTPMPFDNYLDGQTPDFLWFER
                     LLEDQGSGLNKPAAVIVETVQGEGGINVARTEWLRALAALCQRQDMLLIVDDIQMGCGR
                     TGAFFSFEEAGIVPDIVTVSKSISGYGLPMALTLFKPELDIWEPGEHNGTFRGNNPAFV
                     TAAAALDTYWADGQMEKQTLARGEIVEAHLKAIAEEHPGTFAEYRGRGLVWGLECT"
     gene            5001..5405
                     /locus_tag="O1M07_RS12855"
                     /old_locus_tag="O1M07_12850"
     CDS             5001..5405
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ectoine: ectoine_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016907220.1"
                     /locus_tag="O1M07_RS12855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1M07_12850"
                     /product="ectoine synthase"
                     /protein_id="WP_067352988.1"
                     /sec_met_domain="ectoine_synt (E-value: 1.6e-51, bitscore:
                     172.4, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVRSFQEIEGTDRHVKAKSGTWESKRIVLAKERVGFSLHETVLY
                     AGTETSMWYANHIEAVVCVEGVAELTNDETGEKHLITPGVMYLLDGHEKHTMRIKEDFR
                     CLCVFNPPVTGREDHDENGVYPLLTEPEAD"
     gene            5477..6379
                     /gene="thpD"
                     /locus_tag="O1M07_RS12860"
                     /old_locus_tag="O1M07_12855"
     CDS             5477..6379
                     /EC_number="1.14.11.55"
                     /GO_function="GO:0016706 - 2-oxoglutarate-dependent
                     dioxygenase activity [Evidence IEA]"
                     /codon_start=1
                     /gene="thpD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606339.1"
                     /locus_tag="O1M07_RS12860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1M07_12855"
                     /product="ectoine hydroxylase"
                     /protein_id="WP_189857983.1"
                     /sec_met_domain="PhyH (E-value: 3.7e-38, bitscore: 130.9,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTAPERTADLYPTRGTSEVITPRKDPVVWSRPGVEGPFAAAELS
                     DFDRDGFFALPELLTADEVAVYRAELDRLVGDPAMRADPRSIVEPTSQAVRSVFEVHRI
                     SEVFARLVADPRVVGRARQILGSDVYVHQSRINVKPGFGASGFYWHSDFETWHAEDGLP
                     RMRTVSVSIALTENYDTNGGLMIMPGSHRYFVGCEGATPKDNYKKSLQMQDAGTPSDEA
                     LTTMADRHGIRLFTGRAGSATWFDCNAMHGSGDNITPYPRSNVFIVFNSVENAAVEPFA
                     APVRRPEYIGARAPFVPVK"
     gene            complement(6486..>6755)
                     /locus_tag="O1M07_RS12865"
                     /old_locus_tag="O1M07_12860"
                     /pseudo=""
     CDS             complement(6486..>6755)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016574047.1"
                     /locus_tag="O1M07_RS12865"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="O1M07_12860"
                     /product="alkene reductase"
                     /pseudo=""
                     /transl_table=11
                     /translation="ELLARLRKRFGGTLLLNPATEGRPTGPEELPLVERGEADLLAYGA
                     LFLANPDLPRRLAAGGPFNTPDRDGFYGGDDRGYLDYPALDDEN"
     gene            complement(6877..7950)
                     /locus_tag="O1M07_RS12870"
                     /old_locus_tag="O1M07_12865"
     CDS             complement(6877..7950)
                     /NRPS_PKS="Domain: Aminotran_5 (16-349). E-value: 1.6e-18.
                     Score: 58.7. Matches aSDomain:
                     nrpspksdomains_O1M07_RS12870_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018536872.1"
                     /locus_tag="O1M07_RS12870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1M07_12865"
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="WP_189857985.1"
                     /sec_met_domain="Aminotran_5 (E-value: 8.5e-11, bitscore:
                     40.4, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQRHMALGGDEFAPETVYLNSASCGLLPARSAAALTAAAAESASH
                     GTMGRDYLGTGARVRGAFARLMGVPEERVALGSSVAVQSAFVAGSLPVGSEVLVAEGDF
                     SSLVNPLAARAGCTVRVVPREALADAVRPGTALVAVSAVHALDGRIADLAAIRDAARAH
                     GALTYVDITQAAGWLPLRLADFDYTVCGAFKWLLCPRGTTFMVFGGERGEPGGPGWPVP
                     VHAGWVAGEDPGESNYGPIDRPAVTARRYDEPHAHYSYVAAEHSLGLLAELGVDTVHAH
                     NVALAQQYRAGLEAAGFTPRAAPGSAIVSTPGLADAEPRLAQAGVRVSVRGGLLRAAFH
                     LYNSTEDVSRALSLLVP"
     aSDomain        complement(6904..7902)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_O1M07_RS12870_Aminotran_5.1"
                     /evalue="1.60E-18"
                     /label="O1M07_RS12870_Aminotran_5.1"
                     /locus_tag="O1M07_RS12870"
                     /protein_end="349"
                     /protein_start="16"
                     /score="58.7"
                     /tool="antismash"
                     /translation="VYLNSASCGLLPARSAAALTAAAAESASHGTMGRDYLGTGARVRG
                     AFARLMGVPEERVALGSSVAVQSAFVAGSLPVGSEVLVAEGDFSSLVNPLAARAGCTVR
                     VVPREALADAVRPGTALVAVSAVHALDGRIADLAAIRDAARAHGALTYVDITQAAGWLP
                     LRLADFDYTVCGAFKWLLCPRGTTFMVFGGERGEPGGPGWPVPVHAGWVAGEDPGESNY
                     GPIDRPAVTARRYDEPHAHYSYVAAEHSLGLLAELGVDTVHAHNVALAQQYRAGLEAAG
                     FTPRAAPGSAIVSTPGLADAEPRLAQAGVRVSVRGGLLRAAFHLYNSTEDVS"
     gene            complement(8029..8724)
                     /locus_tag="O1M07_RS12875"
                     /old_locus_tag="O1M07_12870"
     CDS             complement(8029..8724)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018536871.1"
                     /locus_tag="O1M07_RS12875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1M07_12870"
                     /product="DsbA family oxidoreductase"
                     /protein_id="WP_102923837.1"
                     /transl_table=11
                     /translation="MRVEIWSDIACPWCYIGKARFEAGLAAFAQRADVEVVHRSFELDP
                     AAPPATDVPILDMLATKYGVSREQAEAMEARVAEAAAGEGLGYRSDRIHGNTFDLHRLL
                     HLAKAHGVQDALLTALYHANFAEARQLADPAVLTGIAVGAGVPEAEAARVLADPDAYAD
                     EVRADERAAAELGATGVPFFVIDRRYGVSGAQPADVFRQALERAHADSAVQVLAADDAD
                     SCGDGSCAV"
     gene            8900..9598
                     /locus_tag="O1M07_RS12880"
                     /old_locus_tag="O1M07_12875"
     CDS             8900..9598
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /GO_function="GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA]"
                     /GO_process="GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018536870.1"
                     /locus_tag="O1M07_RS12880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1M07_12875"
                     /product="bifunctional 2-polyprenyl-6-hydroxyphenol
                     methylase/3-demethylubiquinol 3-O-methyltransferase UbiG"
                     /protein_id="WP_189857987.1"
                     /transl_table=11
                     /translation="MGTPPPHATDGFWESTGATKTFTHPLDAELLAEFVPRTARVLDYG
                     CGYGRLTAELVGSGYRAVRGVDRSAALIARGRREHPGLALMRWAGFPLPFTDRSFDAAL
                     LFAVLTCVPDDAGQRAIVGELGRLVRPGGVLYVSDVPLQDDAFHVGQYERFAARYGMYG
                     VYGVFETEDGGVFRHHPPEWLRGLLREAGFAVLRERRTVVPTLDGRTAERLQIMARREP
                     AGAPAESGTG"
     gene            complement(9546..10112)
                     /locus_tag="O1M07_RS12885"
                     /old_locus_tag="O1M07_12880"
     CDS             complement(9546..10112)
                     /EC_number="2.3.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018536869.1"
                     /locus_tag="O1M07_RS12885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O1M07_12880"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_189857989.1"
                     /transl_table=11
                     /translation="MNAAAPHLTPQVRRATPADLEQIAALHTAARAAYLRGRVPDAPFD
                     APAEHARWRDAWARVLHRDEAPTLCAVHRDTVLGAASYRPHRGHSPRTAPGTTVVLHQL
                     HVDPAHWGTGVGRALHSACLHAWRAAGHSRAVLDVLWHNHRARTFYTRLGWRPDPDRRP
                     APDATHLALTLCLTPPEHRPAPAGP"
ORIGIN
        1 cgggaccggg cgaccaccga ccgcttcgtg gccgccctgg cggacgtgct cggcgagccg
       61 gcccggtaga gcgggcgggg tgcgccgcgc gggcccgcgc ggcgcacccg tccccaccag
      121 cgcccggcgc cccccacggc accgatgcgc tggggatgcc tcccccgccg tgcgggcgaa
      181 gggagggtcc gtcagccgcg cccgtccggc gcggcgctcc ggcggcgggt gtggaccatc
      241 gccccggcgc cgccggcgac cagcaggacc gcaccgccga cgaggtacgg ggtggcggcg
      301 ctgccgccgg tctcggcgag gttctcggtg gccgggcggg cgccgccccc ggtgtgcgcc
      361 tgggtgccgg tgcccggctc gtgggcctga ccggggtgcg ccggggtgcc gggcttgtcc
      421 ggggtgccgt gcggggtggt gcaggtggcc tgggccagcg tgacctggcc gtgcacctcc
      481 gcgacgttga gcttcaacgg gttgacggag acccggagtt ggagcgcggt ggcggcggcg
      541 ctcgccgagg tggtgctctt ctgcgacagg tcgagccgga cgtcgccgac gccgggcacg
      601 tcgacctcgg tggtcccgcc ggcacggagc gcgacccgct tgcccagcac cacgacgtcg
      661 cccagcacct gggactcggc ccgcggacgc tgtcctgccg tgcagacggc gcgggcggtg
      721 acctgctgga cctcggccag cggcagcgcc ggcaggccgg ggagctggac cttggcccgg
      781 acgaggtcgg cgtggccctc ggtggtccgc ccgtcggcgg tggcccgggc ggtggcgacg
      841 tcggcccgca gcaggctgac cggccggccg ccgtcgatgc cgtccagccg gacggtgagc
      901 gcggtcttgt cggccgaggc cggggcgtgg acctcgtcga ggacggcccg gacggggacg
      961 ttcaggctct tgtcgagcag gttgacgtcc agggcggtgc gcagcaccac cgcccccgag
     1021 gtgccgtggc cacgggcgtc gtcgccggtg gcgtacgcgg cgggcgcggc ggcgagggcg
     1081 acggcgggac cggccgtcag gacggcggcg gccagcacgg cgccgatccg cccggtggtg
     1141 ccggtcgagc cggcgaatgt ggtggaacgg gtggacacgg gtgtggaacc cccacaggag
     1201 agatggcgcc gccgaccgcg ccaatggggg acatcacgcg ggccgacggc atcgactcgc
     1261 acatcgtgta cgcacggagg gtgaacggtt agccacgcga ggtcagttca ccccaatggg
     1321 ttattttcgc gccttcattc gatttccccc cgacgcctcc gccccggcgg gcctcccccg
     1381 tcacagccgt accgggccat gggggcccgg cacggcccgc cgggcggggt gccgaaggtc
     1441 gctcagccca cgacccggcc gcgcagcacc accaggcgcg gcgccgccag cacccggacg
     1501 tcggcccgcg ggtcggcctc gtagacgacc agatccgcgg aggcgccctc ggtgagcccg
     1561 gggcggccga gccactcccg ggcgccccag gtcgtcgccg agagggcggc ctcgacgggc
     1621 agccccgcct tcatcagctc ggcgacctcg tcagcgacca ggccgtgcgg cagcgagccg
     1681 ccggcgtcgg tgccggcgaa gatcgggacg ccggcgtcgt aggcggcccg cacggtgtcg
     1741 tagcgccggg cgtgcagccg gcgcatgtgg tccgcccagc gcgggaactt cgcctcgccg
     1801 ccggccgcga gctgcgggaa ggtcgcgatg ttgaccagcg tggggacgat cgcgacctgg
     1861 cgctcggcga agagcgggat ggtgtcctcg gtcaggccgg tggcgtgctc gatgcagtcg
     1921 atgccggcct cgaccagcgg ggcgagggac tcctcggcga agcagtgggc ggtgacccgc
     1981 gcgccgagcc ggtgcgcctc ggcgatggcg gcggccacct cgccgggcgg ccagcaggcg
     2041 gccaggtcgc cggtggagcg gtcgatccag tcgccgacga gcttgaccca gccgtcgccg
     2101 cgccgggcct cctgggcgac gtaggcgacc aggtcggccg gctcgatctc gtgcgcgtag
     2161 ttgcggatgt agcgcctggt gcgggcgatg tgccggccgg cgcggatgat ccgcggcagg
     2221 tcggggcggt cgtcgatcca gcgggtgtcc gagggcgagc cggcgtcccg gatcaggagg
     2281 gtgccggcgt cccggtcggt gagcgcctgc ttctcgctgg tggcggcgtc caccggcccg
     2341 tgcgcgtcca gtccgacgtg gcagtgggcg tcgaccaggc ccggcagcac ccagccggtc
     2401 acggtcctgg catcgcgtgc cagggtcggc cgctcgaagc tgacccggcc gtcgatgacc
     2461 cacagctcgt cgcggacgtc gtccggcccg acgaggaccc tccccttgag gtgcagcacc
     2521 gcaccttcac tcatggacgt catgcacgca ctgtatgcgg gggcccgagc cggcggccac
     2581 ggtgtgcgaa gggcccgcgc cgaccatgct ccggggggct tttcgaaaac ccgcggcgcg
     2641 cccgggacgc acccaggcgc ggggtttccg ccatctcgcc ggaagcgctt gacggaactt
     2701 ctcgcacggc tttcaaggaa gcgcctggaa cgccttctac cggcgaattc cctattcctc
     2761 agaagagcag cttcccgtat tcttatgccc gctttcccca agctcaaacg ccaagatttc
     2821 gctagtaccg agtctcataa ttcaggcact tcgcgggagc gttacgaagc tgtgactgac
     2881 tacacagcgt gtccatttcg ccccgaacta tcggaccaaa ccatgacact ttgcaaccgg
     2941 ttcgcgcgct cgtgcgcccc cgcgtgataa cacagatcag gttctcacgt aacccctgcc
     3001 cgcgatgcaa tttgcttttc gcctcggtaa atttaatttc catgaccgcc gcacaagcag
     3061 accatgccgg tgcccgaagc gaaatcagag aaataccgga gggcttcaag ctcgacaccc
     3121 cccgggtgga ggacggggcc gcgatctggc gcatcgcccg cgactcgaag acgctggacc
     3181 tgaactcctc ctacagctac ctcctgtggt gccgcgactt cgccgccacc tccgccgtcg
     3241 cccgcgacgc gacgggcgag ccggccgcgt tcatcaccgg ctatctgcgc ccggaccgcc
     3301 cggacaccct cgtcgtctgg caggtcgccg tcgacgcggc gcaccgcggg cggggcctgg
     3361 ccgccgccct gctggacggg ctgaccaccc gtgccgccga cgaactgggc gtccgccgcg
     3421 tggagaccac ggtctcgccc ggcaacaccg cctccaaccg gctgttcgcc tccttcgccg
     3481 agcggcactc ggtgccgatc gagcgcgagg tgctcttcga cgcggcgctc ttccccgagc
     3541 agggccacga ggcggaggtc ctgcacctca taggcccgtt cgaggcgccg cccggcggca
     3601 gacgctgacc ctggccgcac gcacggcgcc acccccggac ttctccctcc ccgcactcat
     3661 ctcccaggag catgctgtga ccctcaccca gcccgatctg agcgtcttcg aaaccgtcga
     3721 gtcggaggtg cgcagctact gccgtggctg gcccaccgtc ttcgaccgcg cccagggcag
     3781 ccgcctgacc gacgaggacg gccacaccta cctggacttc ttcgccggtg ccggttcgct
     3841 caactacggg cacaacaacg cggtcctcaa acgcgccctg ctcgactaca tcgagcggga
     3901 cggcatcacc cacggcctgg acatgtccac cacggccaag cgggccttcc tggagtcgtt
     3961 ccagaacatc atcctgcggc cccgcgacct gccctacaag gtcatgttcc cgggcccgac
     4021 gggcgccaac tccgtcgagg ccgcgctcaa gctggcccgg aaggtcaagg gccgcgagtc
     4081 gatcgtgtcc ttcaccaacg ccttccacgg catgtcgctg ggcgccctcg cggtcaccgg
     4141 caactccatg aagcgggccg gcgccggcat cccgctggtg cacggcaccc cgatgccgtt
     4201 cgacaactac ctcgacggcc agacgccgga cttcctgtgg ttcgagcggc tgctggagga
     4261 ccagggctcg ggcctgaaca agcccgcggc cgtgatcgtg gagaccgtgc agggcgaggg
     4321 cgggatcaac gtcgcccgca ccgagtggct gcgcgccctg gccgccctgt gccagcgcca
     4381 ggacatgctg ctgatcgtcg acgacatcca gatgggctgc ggccgtacgg gtgccttctt
     4441 ctccttcgag gaggcgggca tcgtgccgga catcgtcacc gtctccaagt ccatcagcgg
     4501 ctacggactg ccgatggcgc tcaccctgtt caagccggag ctggacatct gggagcccgg
     4561 cgagcacaac ggcaccttcc gcggcaacaa cccggcgttc gtcaccgcgg ccgccgccct
     4621 ggacacgtac tgggccgacg gtcagatgga gaagcagacg ctggcccgcg gtgagatcgt
     4681 cgaggcgcac ctgaaggcca tcgccgagga gcacccgggc accttcgccg agtaccgcgg
     4741 ccgcggtctg gtgtggggcc tggagtgcac cgacaagagc ctcgccaaca agatcgcggg
     4801 gcgcgccttc gagctgggtc tgctgatcga gacctccggc ccggagagcg aggtcgtcaa
     4861 actgctgccc gcgctgacga ccacccccga ggaactggac gagggcctgc ggatcctcgc
     4921 ccgcgcggtc cgcgactgcg cctgaccgcg gccccgcgcc gacatccctc gccgaaccac
     4981 agaaaggcat ccgacgcacc atgatcgtcc gctcgttcca ggagatcgaa ggcaccgacc
     5041 gccacgtcaa ggccaagtcc ggcacgtggg agagcaagcg catcgtgctc gccaaggagc
     5101 gggtcggctt ctcgctccac gagacggtcc tctacgccgg caccgagacg tccatgtggt
     5161 acgccaacca catcgaggcc gtggtctgcg tcgagggcgt cgccgagctg accaacgacg
     5221 agaccggcga gaagcacctc atcacgcccg gcgtgatgta cctgctcgac gggcacgaga
     5281 agcacaccat gcggatcaag gaggacttcc gctgcctgtg cgtcttcaac ccgccggtca
     5341 ccggtcgcga ggaccacgac gagaacggcg tctacccgct gctcaccgag cccgaggcgg
     5401 actgagctgc accgctaccg ccgcgggccg ccgcgatgcc atgagattcc gtacgagagg
     5461 agaggaaggc accaccatga ccaccgcacc cgagcgcacc gccgacctgt acccgacccg
     5521 tgggacctcc gaggtcatca ccccgcggaa ggacccggtg gtgtggtcgc ggcccggagt
     5581 cgaggggccc ttcgccgctg ccgagctgag cgacttcgac cgtgacggct tcttcgcgct
     5641 gccggagctg ctcaccgcgg acgaggtcgc ggtgtaccgc gccgagctgg accggctggt
     5701 gggcgacccg gcgatgcgcg ccgacccgcg ctcgatcgtc gagccgacgt cgcaggccgt
     5761 ccgctcggtc ttcgaagtcc accggatcag cgaggtgttc gcgagactgg tcgccgaccc
     5821 ccgggtggtc ggccgggccc ggcagatcct cggctcggac gtctacgtcc accagtcgcg
     5881 gatcaacgtc aagcccgggt tcggtgcctc cggcttctac tggcactcgg acttcgagac
     5941 ctggcacgcc gaggacgggc tgccgcgcat gcgcacggtg tcggtctcga tcgcgctgac
     6001 cgagaactac gacaccaacg gcggcctgat gatcatgccc gggtcgcacc ggtacttcgt
     6061 cgggtgcgag ggcgccaccc cgaaggacaa ctacaagaag tcgctccaga tgcaggacgc
     6121 ggggacgccg tcggacgagg cgctgacgac gatggcggac cggcacggca tccgcctgtt
     6181 caccggccgg gccggctcgg cgacctggtt cgactgcaac gccatgcacg gctccggcga
     6241 caacatcacg ccgtacccgc gcagcaacgt cttcatcgtc ttcaacagcg tggagaacgc
     6301 cgcggtggag ccgttcgcgg ccccggtccg gcgcccggag tacatcgggg cgcgcgcccc
     6361 gttcgttccg gtcaaatagg ggacggccgg tgctccggca ccgggcaggg aagcggggcg
     6421 gccccgcgcg cggccgccgc acggcaccac aggggtgcgg tgcggcggcc gccgccgacg
     6481 ctccgtcagt tctcgtcgtc cagcgcgggg tagtccagat agccgcggtc gtcgccgccg
     6541 tagaagccgt ccctgtccgg ggtgttgaac gggccgccgg cggccagccg gcggggcagg
     6601 tcggggttgg cgaggaacag cgcgccgtac gccagcaggt cggcctcgcc gcgctcgacg
     6661 agcgggagct cctcggggcc ggtgggccgg ccttcggtgg ccgggttgag caggagcgtg
     6721 ccgccgaacc gcttccgcag ccgggccagc agctctcact gacggccttt cagcggattg
     6781 tgatggtccg tcaactcggc tgtcgagccg aaccatcggc cattacctca gcggccaatg
     6841 cccgccccgt attcccctgg ggtcccgaac cgcccgtcac ggaaccaaca gggacagcgc
     6901 ccggctcacg tcctcggtcg agttgtagag gtggaacgcc gcccggagca gcccgccgcg
     6961 gaccgagacc cgcacaccgg cctgagcgag ccgcggttcg gcgtccgcca gccccggggt
     7021 ggagacgatc gcggacccgg gcgcggcccg cggggtgaag ccggcggcct ccagcccggc
     7081 ccggtactgc tgcgccagcg cgacgttgtg ggcgtggacg gtgtccacgc cgagctccgc
     7141 gagcagcccg agggagtgct cggcggccac gtaggagtag tgggcgtgcg gctcgtcgta
     7201 gcggcgggcg gtcaccgccg gccggtcgat cggaccgtag ttggactccc ccgggtcctc
     7261 cccggcgacc caccccgcgt gcaccggcac cggccacccc gggccgcccg gctccccccg
     7321 ctccccgccg aagaccatga acgtcgtccc gcgcgggcac agcagccact tgaacgcccc
     7381 gcacaccgtg tagtcgaagt ccgcgagccg cagcggcagc cagcccgccg cctgtgtgat
     7441 gtcgacatac gtcagcgccc cgtgcgcccg ggcggcgtcc cggatggcgg ccaggtcggc
     7501 gatccggccg tccagcgcgt gcaccgcgct caccgcgacc agcgccgtcc cgggccgcac
     7561 cgcgtcggcg agcgcctccc gcggcaccac ccgcaccgtg catccggcgc gcgccgccag
     7621 cgggttcacc agggagctga agtccccctc ggcgaccagc acttcgctgc cgaccggcag
     7681 cgagcccgcg acgaacgccg actgcaccgc gaccgaactg cccagcgcca cccgctcctc
     7741 gggcaccccc atcagccggg cgaaggcgcc gcgcacccgg gcgcccgtgc cgaggtagtc
     7801 gcgccccatc gtcccgtgcg acgccgactc cgccgcggcg gcggtcagcg cggcggcgct
     7861 ccgcgcgggc agcagcccgc aggacgccga gttcagatag accgtctcgg gcgcgaactc
     7921 gtcgccgccc agtgccatgt gtcgctgcat ggccccactc tgctcggtgg ccgccccggc
     7981 gtccacggga atgccgggcc gcgacgccgg ggcggaccgg ccggtgggtc agaccgcgca
     8041 gctcccgtcg ccgcagctgt ccgcgtcgtc ggcggccagc acctggacgg cggagtcggc
     8101 gtgcgcccgc tccagggcct gacggaagac gtcggcgggc tgggcgccgg agacgccgta
     8161 gcggcggtcg atgacgaaga aggggacgcc ggtggcgccc agctcggcgg cggcgcgctc
     8221 gtcggcccgg acctcgtcgg cgtaggcgtc cgggtcggcg aggacccgcg cggcctcggc
     8281 ctcgggcacg ccggccccga ccgcgatccc ggtcagcacc gcggggtccg cgagctgccg
     8341 ggcctcggcg aagttggcgt ggtagagggc ggtgagcagc gcgtcctgga cgccgtgcgc
     8401 cttggccagg tggagcagcc ggtgcaggtc gaaggtgttg ccgtggatgc ggtcggagcg
     8461 gtagcccagc ccctcgccgg ccgccgcctc ggccacgcgg gcctccatcg cctcggcctg
     8521 ttcccggctg acgccgtact tcgtcgcgag catgtccagg atcgggacgt cggtggccgg
     8581 cggggcggcc gggtccagtt cgaaggaacg gtggacgacc tcgacgtccg cccgctgggc
     8641 gaaggccgcc agaccggcct cgaaccgggc cttgccgatg tagcaccagg ggcaggcgat
     8701 gtccgaccag atttcgacgc gcatggggat gactctcgat gactttcctc ggggggaccg
     8761 gcccgcggcc gatcaggggt acgaaggggt gcaacggtgc cggcgggggg cttattccgg
     8821 aagccccccg ggcgtcccga acgggtcggc cgccgcgcga tgcgccggat gcgcgtcggc
     8881 cgggcggtac cgtcccgcta tgggcacgcc accaccgcac gcgaccgacg ggttctggga
     8941 gtcgaccggg gccaccaaga cgttcacgca tccgctcgac gccgagctgc tggcggagtt
     9001 cgtaccgcgg accgcgcggg tgctggacta cggctgcggg tacgggcggc tcaccgccga
     9061 actggtcggg tcggggtacc gggcggtgcg cggggtggac cggtccgcgg cgctgatcgc
     9121 gcgggggcgg cgggagcatc cggggctggc cctgatgcgc tgggccgggt tcccgctgcc
     9181 gttcacggac cgcagtttcg acgcggcgct gctgttcgcg gtgctgacct gtgtgccgga
     9241 cgacgccggc cagcgggcga tcgtcgggga gctggggcgg ctggtgcggc ccggtggggt
     9301 gctctacgtg agcgatgtgc cgctgcagga cgacgcgttc cacgtcgggc agtacgagcg
     9361 gttcgcggcg cggtacggga tgtacggggt gtacggggtg ttcgagacgg aggacggcgg
     9421 ggtgttccgg caccatccgc cggagtggct gcgggggctg ctgcgggagg cgggtttcgc
     9481 ggtgctgcgg gagcgccgca cggtggtgcc gacgctggac ggccgcaccg ccgagcggct
     9541 gcagatcatg gcccggcggg agccggccgg tgctccggcg gagtcaggca cagggtgagt
     9601 gccaggtggg tggcgtcggg ggcggggcgg cggtccgggt cggggcgcca gcccagccgg
     9661 gtgtagaagg tgcgggcgcg gtggttgtgc cagagcacgt cgaggacggc ccgggagtgg
     9721 ccggcggcgc gccaggcgtg cagacaggcg gagtgcaggg cacggcccac gccggtgccc
     9781 cagtgggcag gatcgacgtg cagttggtgc aacacgacgg tggtcccggg ggcggtgcgc
     9841 ggggagtgtc cccgatgggg gcggtaggag gcggcgccga ggacggtgtc gcggtggacg
     9901 gcgcagaggg tgggggcctc gtcgcggtgc agcaccctgg cccaggcgtc ccgccagcgg
     9961 gcgtgctcgg ccggcgcgtc gaacggcgcg tccggcaccc ggccgcggag gtaggcggcg
    10021 cgggcggcgg tgtgcagtgc ggcgatctgc tccaggtcgg cgggggtggc gcggcggacc
    10081 tgcggggtga ggtgcggcgc ggcggcgttc acgggccggt cccgtcccct gccggcgggc
    10141 caccggcccg gcgcccgccc ggctcctcgg cccggccgtc gacccggcgc ggcagcccca
    10201 gcgggttggc gtcgcgcagc tcgggcggga ggagggccgg cggggtgtcc tggtaggcga
    10261 ccgggcgcag ccagcgctcg acggcggtgg cgccgacgga ggtggcggtg gaggtggtgg
    10321 ccgggtaggg gccgccgtgg tgctgggcgg gggcgaccgc gacgccggtg ggccagccgt
    10381 tgaccacgac ccggccggcg agcgg
//
