LOCUS       NZ_CP113950            20297 bp    DNA     circular CON 28-JAN-2024
DEFINITION  Myxococcus sp. NMCA1 chromosome, complete genome.
ACCESSION   NZ_CP113950
VERSION     NZ_CP113950.1
KEYWORDS    RefSeq.
SOURCE      Myxococcus sp. NMCA1
  ORGANISM  Myxococcus sp. NMCA1
            Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
            Myxococcaceae; Myxococcus.
REFERENCE   1  (bases 1 to 9502182)
  AUTHORS   Ahearne,A., Stevens,C. and Phillips,K.
  TITLE     Minimal conservation of predation-associated metabolite biosynthetic
            gene clusters underscores biosynthetic potential of Myxococcota
            including descriptions for ten novel species: Archangium lansinium
            sp. nov., Myxococcus landrumus sp. nov., Nannocystis bai
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9502182)
  AUTHORS   Ahearne,A., Stevens,C. and Phillips,K.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-NOV-2022) Biomolecular sciences, University of
            Mississippi, Faser Hall 407, Oxford, MS 38655, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 10.1.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200x
            Sequencing Technology             :: PacBio Sequel II
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/28/2024 03:49:16
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,878
            CDSs (total)                      :: 7,793
            Genes (coding)                    :: 7,662
            CDSs (with protein)               :: 7,662
            Genes (RNA)                       :: 85
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 56 of 131
            Pseudo Genes (incomplete)         :: 88 of 131
            Pseudo Genes (internal stop)      :: 13 of 131
            Pseudo Genes (multiple problems)  :: 24 of 131
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:28:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4597812
            Orig. end                         :: 4618109
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP113950.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20297
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="12"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..20297
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20297
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10297](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10297
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     gene            complement(314..1027)
                     /locus_tag="OZ403_RS19300"
                     /old_locus_tag="OZ403_19300"
     CDS             complement(314..1027)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011553733.1"
                     /locus_tag="OZ403_RS19300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OZ403_19300"
                     /product="hypothetical protein"
                     /protein_id="WP_140791840.1"
                     /transl_table=11
                     /translation="MAGTRPGEASDEDTSSLGSDAVMFRAPLLPCPAASPAGQRNRRTN
                     MATHKVGGEVDALCTRCKLTLAHTILAMVGTKIARVRCNTCGGDHAYRGAPGATDRPSS
                     STTRTTRTSSSSSSASAKAEKIIISFEEQLAGKDVANAPRYSPKDTYKVDQVIQHPTFG
                     TGYVSAVRGDKVDITFRTDTKTLVHGRGGGPVEKPVFNPPNRQVTGPADKPQPVGDSAE
                     PAPADGAEPPPASED"
     misc_feature    complement(944..946)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    1055..1068
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.27"
                     /tool="antismash"
     gene            1058..1873
                     /locus_tag="OZ403_RS19305"
                     /old_locus_tag="OZ403_19305"
     CDS             1058..1873
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011553734.1"
                     /locus_tag="OZ403_RS19305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OZ403_19305"
                     /product="ABC transporter permease"
                     /protein_id="WP_140791842.1"
                     /transl_table=11
                     /translation="MTTQTPSKPAREPGPFTQAVTRFGQGLIDIVSTLGGIITMGLDVF
                     RWSVRRPFRLVNLFAQLDFVGVGSIFIVSLTGTFTGMVFALQTSTAFRLFDAESLVGPT
                     VALTLTRELAAVFSALMVTMRAGSAMCTELGTMRVTEQVDALETMAVNPVQYLLVPRVL
                     AGLFMVPALTMLFNTMGMGGAYVVAVGGLGISPGTFLTRTQQWLAPEDIFQGLLKGAVF
                     GLAVSLICCFKGFNASGGAKGVGQATTEAMVASALSIFILDFILGVLFF"
     gene            1915..2652
                     /locus_tag="OZ403_RS19310"
                     /old_locus_tag="OZ403_19310"
     CDS             1915..2652
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013940347.1"
                     /locus_tag="OZ403_RS19310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OZ403_19310"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_140800708.1"
                     /transl_table=11
                     /translation="MIQVVDLHKTFGDHKVLTGINLTVPAGSTCVILGGSGSGKTVLMK
                     HMIGLLKPDRGQVIVDGEDIVPMSVESLQRVRNKFGMVFQAAALFDSMTVFENVAFPLR
                     EHTKDPEDVIRQKVRARLDLMGLKKDVEDRFPADLSGGMRKRVGLARAIVMDPKVVLYD
                     EPTTGLDPITTDYVDEMILAAQKELGVTSVVISHDISSAFNVADQIAFLSKGVIVASGS
                     PEQLREADHPAVKVFLETWFGKN"
     gene            2758..4287
                     /locus_tag="OZ403_RS19315"
                     /old_locus_tag="OZ403_19315"
     CDS             2758..4287
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011553736.1"
                     /locus_tag="OZ403_RS19315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OZ403_19315"
                     /product="MlaD family protein"
                     /protein_id="WP_140791843.1"
                     /transl_table=11
                     /translation="MKKLVTPFRVGLLVIAAGAFFVTFVLFARKGGLSDSESTRVWAYF
                     RDASGLAVRGRVQIAGIPVGEIDDISLEGTRAKVWLKIRNDVDLREDAVVTKRSESLLG
                     DYLLDLNPGTEGAPSLETGGQIRRVVDTQGMEAVFESLSQITADIQEVTGALREVLGGE
                     RGAGSLQRIVENLVRLSDSVDATVRRNADRLDTIVGNVEAISADVRGITQGNQAEITRI
                     IDNIEFITRDVRQVLGSVKNIVGTGEGDVKETVASLKETLKKLDGTLGNLEEITRKVKD
                     GEGAAGVLLADEAVGRELRETVQDVSRFASRLTDLQAEIGIQSTYLAAQGNSKNVFSVR
                     LIPKPDKYYLLELVDDPRGSVTTEVLQTNPPSEGDPVVQTRKVTKESLKVSAQFAKRWY
                     FTTLRVGLIESTGGVGADLHFFNDALRFQVDAFNFADDELRYPRLRASLRAQPLDHLYL
                     IAGMDDMLNAQQRDLATRRLVAGRDFFVGGGLFFTDDDLKAILTLTGIPTP"
     misc_feature    complement(4362..4378)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 21.34"
                     /tool="antismash"
     gene            4399..5325
                     /locus_tag="OZ403_RS19320"
                     /old_locus_tag="OZ403_19320"
     CDS             4399..5325
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1276: PfkB domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011553737.1"
                     /locus_tag="OZ403_RS19320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OZ403_19320"
                     /product="PfkB family carbohydrate kinase"
                     /protein_id="WP_140791845.1"
                     /transl_table=11
                     /translation="MSLLVVGSVALDSVETPFGQKEDILGGSATYFSTSASFFSPARVV
                     AVVGEDFPEGHLNFLRGRGIDLEGLTRETGRTFRWKGRYSYELNEAQTLDTQLNVFQAF
                     SPKLPESYRDTPYVFLGNIHPELQAQVLDQVKAPKLVAADTMNFWIKGSRAALLKTLSR
                     VNLLFVNDAEARQLAGEHNVVKAARAIMAMGPQRVVIKRGEYGALLFEAEHIFACPAFP
                     LAEVFDPTGAGDTFAGGFMGALATSNGVLDQALLRRAMVMGSVMASFTVEKFSLERLRE
                     VTRPEIHARFAEFRKLTHFDDLGPLER"
     gene            5426..5779
                     /locus_tag="OZ403_RS19325"
                     /old_locus_tag="OZ403_19325"
     CDS             5426..5779
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013940350.1"
                     /locus_tag="OZ403_RS19325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OZ403_19325"
                     /product="TIGR02266 family protein"
                     /protein_id="WP_217917601.1"
                     /transl_table=11
                     /translation="MSENRKSTRIPTQLRCWCEGDNVTLYARISNLSEGGLFLRTSTPL
                     ARGARTVVKLSPAGHQDIQAQATVVWLREAEERALPAGMGLRFESLDSDTLGRLRQMIS
                     QQQQNQVKAGWAG"
     gene            5807..6538
                     /locus_tag="OZ403_RS19330"
                     /old_locus_tag="OZ403_19330"
     CDS             5807..6538
                     /GO_function="GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Metallophos_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014397091.1"
                     /locus_tag="OZ403_RS19330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OZ403_19330"
                     /product="metallophosphoesterase family protein"
                     /protein_id="WP_002640070.1"
                     /sec_met_domain="Metallophos_2 (E-value: 9.7e-21, bitscore:
                     73.3, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIAVISDIHSNIEALTEVLRVAEHQKVDRFVSLGDIVGYGASPN
                     PCCELVRSVAEVTLLGNHDAAVAGRMDYSYYYDAARHALDWSANVLTDENMAWLRSLPY
                     TYRIGDVGFCHGSPIDPKAYEYIFALEQARELTPYVAELPEVTFIGHSHLCRAFAIGNG
                     EVNDVVAQKFGIRRGYKYIISVGSVGQPRDYDNRACFVICDTDARTVEYIRVEYDIETS
                     AQKIFDADLALNFGKRLFLGV"
     gene            6597..7319
                     /locus_tag="OZ403_RS19335"
                     /old_locus_tag="OZ403_19335"
     CDS             6597..7319
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011553739.1"
                     /locus_tag="OZ403_RS19335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OZ403_19335"
                     /product="hypothetical protein"
                     /protein_id="WP_140791846.1"
                     /transl_table=11
                     /translation="MRTLVLRASLRPLVGVVSAVLLTLAPTACRREPPAPSAEYEEAAR
                     RFRELYAQKLDDAFLDPQVGEIEAKLQRVPADSLDAEGARELLQRIKDGRNRMAAAANE
                     RDEAVASARELPPGSYTAPSTEESARPAAPVEAPDAGPPDAGAGGGPQAGTAASELVAG
                     FRGCFQRGTPIDVQGRGMRETWQLADRTACRLEYPQHQDSFLLIEEGKVLTLLPKSAVQ
                     TVPVTPDGGPAPATDAGR"
     misc_feature    7242..7244
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            7335..8177
                     /gene="asd"
                     /locus_tag="OZ403_RS19340"
                     /old_locus_tag="OZ403_19340"
     CDS             7335..8177
                     /EC_number="4.1.1.65"
                     /GO_function="GO:0004609 - phosphatidylserine decarboxylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="asd"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011553740.1"
                     /locus_tag="OZ403_RS19340"
                     /note="Phosphatidylserine decarboxylase is synthesized as a
                     single chain precursor. Generation of the pyruvoyl active
                     site from a Ser is coupled to cleavage of a Gly-Ser bond
                     between the larger (beta) and smaller (alpha chains). It is
                     an integral membrane protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="OZ403_19340"
                     /product="archaetidylserine decarboxylase"
                     /protein_id="WP_140798498.1"
                     /transl_table=11
                     /translation="MNDQTFMKLMQVLPKSALSTVVGMATRLPVPAPVHQAAMRAFAKA
                     YNVDMEEAEHSFDHYPTFAQFFTRGLKPGLRPVDAGEKVVVSPVDGRVSQVGYSDYGRC
                     LQAKGIEYTVDELLGDSEAAKPFHGGAWTTIYLSPRDYHRIHAPLGGTITGYAYIPGEF
                     WPVNPASVKNKQSLFCVNERLVTYLDTVAGKCAVVKVGATCVSRIKAAYDEVTTHTGQP
                     GKVHRYGAAMPVEKGGELGRFEMGSTVILLFEPKRVTWDDSLQEEAVVRLGKRIGAIT"
     gene            8204..9451
                     /gene="hisS"
                     /locus_tag="OZ403_RS19345"
                     /old_locus_tag="OZ403_19345"
     CDS             8204..9451
                     /EC_number="6.1.1.21"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hisS"
                     /gene_functions="other (smcogs) SMCOG1162: threonyl-tRNA
                     synthetase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011553741.1"
                     /locus_tag="OZ403_RS19345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OZ403_19345"
                     /product="histidine--tRNA ligase"
                     /protein_id="WP_328285542.1"
                     /transl_table=11
                     /translation="MNDLLPGEIEIWQHVEGLARELFGRFGYGEIRTPMVEDTALFVRS
                     VGEETDIVGKEMYTFNDKADRSLSLRPEGTAPAARAYIEHSIANQEPLTRWFYTGPMFR
                     YERMKTGRYRQFYQIGAEAYGAKEGAQDVEMMDMVVQFLERLGLKDITLNINSLGDEAC
                     RPAYHTKLVEYLQAHREELCADCQKRMEKNPLRVLDCKNEKCQAIAAAGPNVLESLCEP
                     CRAHFDDVQRKLTALGIRHVVNPRMVRGLDYYTRTVFEFIASHPALGTASTVGAGGRYD
                     KLVKSLGGPDAPAVGFACGLDRLVLLLKESGQQFAVRPDVFVAVADAGSHDAALVLASR
                     LRREGLRVEFDTRGGSLKSQMKRADKSGADFTLVLGEVERTSGQAKLKPMAGGEPIPVA
                     LDEVARVVRERKAVPA"
     gene            9666..10004
                     /locus_tag="OZ403_RS19350"
                     /old_locus_tag="OZ403_19350"
     CDS             9666..10004
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013940355.1"
                     /locus_tag="OZ403_RS19350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OZ403_19350"
                     /product="S24/S26 family peptidase"
                     /protein_id="WP_174258828.1"
                     /transl_table=11
                     /translation="MWPSLRSGDHAGVEPLEGAPRPGDVLLARFDHALVLHRLRRWEAG
                     AVALRGDNSPQEDPPLAPTRVLGRVRRVRRGGVVLETGWDRGPRWLGRLRVAVKWRLAA
                     LLGRGGAR"
     gene            10001..10297
                     /locus_tag="OZ403_RS19355"
                     /old_locus_tag="OZ403_19355"
     CDS             10001..10297
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011553743.1"
                     /locus_tag="OZ403_RS19355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OZ403_19355"
                     /product="PqqD family protein"
                     /protein_id="WP_140798500.1"
                     /sec_met_domain="PqqD_RRE (E-value: 8.8e-08, bitscore:
                     30.6, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2.2e-11,
                     bitscore: 42.4, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 2.2e-14, bitscore: 52.3,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAEFAADHAPRWREGVSGQRFGSDFIVLDAEGNTLRGLNGTAIE
                     IWELCDGTRTARALVEQVAQRHGWDVEQVLTDTLKFFSELTRLGLIDELEEAR"
     aSDomain        10013..10276
                     /aSDomain="PqqD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing protein in a pyrroloquinoline
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_OZ403_RS19355_PqqD_RRE.1"
                     /evalue="3.20E-10"
                     /identifier="RREFam006.1"
                     /label="OZ403_RS19355"
                     /locus_tag="OZ403_RS19355"
                     /protein_end="92"
                     /protein_start="4"
                     /score="30.6"
                     /tool="antismash"
                     /translation="FAADHAPRWREGVSGQRFGSDFIVLDAEGNTLRGLNGTAIEIWEL
                     CDGTRTARALVEQVAQRHGWDVEQVLTDTLKFFSELTRLGLID"
     aSDomain        10037..10276
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_OZ403_RS19355_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="7.90E-14"
                     /identifier="RREFam002.1"
                     /label="OZ403_RS19355"
                     /locus_tag="OZ403_RS19355"
                     /protein_end="92"
                     /protein_start="12"
                     /score="42.4"
                     /tool="antismash"
                     /translation="WREGVSGQRFGSDFIVLDAEGNTLRGLNGTAIEIWELCDGTRTAR
                     ALVEQVAQRHGWDVEQVLTDTLKFFSELTRLGLID"
     gene            10297..10830
                     /locus_tag="OZ403_RS19360"
                     /old_locus_tag="OZ403_19360"
     CDS             10297..10830
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013940357.1"
                     /locus_tag="OZ403_RS19360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OZ403_19360"
                     /product="hypothetical protein"
                     /protein_id="WP_174258829.1"
                     /transl_table=11
                     /translation="MRTRLALLAAAVMLASCTEGVAPYAPVHAPPAQEPVAPTDVLPPR
                     EGSEARPPPAPVEEPEVPPPPPPVVPRGSATVIDLGEGRRGLLSVEQVDVDLTVSGVRG
                     RHTVSVEFVPPSGLPYERRSAEVDSRVDESRTVRFSLPVAGTAVATSGMSGTWQARFFL
                     DGAPLTAASFTLDP"
     gene            10842..13940
                     /locus_tag="OZ403_RS19365"
                     /old_locus_tag="OZ403_19365"
     CDS             10842..13940
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011553745.1"
                     /locus_tag="OZ403_RS19365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OZ403_19365"
                     /product="PQQ-binding-like beta-propeller repeat protein"
                     /protein_id="WP_268784810.1"
                     /transl_table=11
                     /translation="MRPFSAPLVAAAALLAPSLGWAQSMSPTAVLTTQPQGGDTRARVV
                     MDEASELTVDVRNNTFSWSPLFRRINEVWFALPNGYIPLASIPPPGWTVDYIANERWVI
                     FYNQDSCNGSGDYGLGQDESARFVLRVVPPTSNNDQNNERFIASQTFARDTCAGGDFTT
                     SVTTSAASWIRSGLYTQVDVRPRVMGVGGDIDARMVVENRTGTNHNNTTVEGPSTGAGA
                     VTFQVVDTEPTPFRMNIASRNAGVYSARVRTGSAGTLVARVRGVSGNGNTVSPAMDARM
                     VNVGALPVAMDVDTDDAFNNELVRVRLTVTNPTSTDTFLNVTPRAPVFQGTAAASLVSG
                     PGPASVPRLDPGASAHFVWTYQLTGSPFANYRFRGQVDATRNGASVTSNLVDSNQGRIV
                     QHRVRTNISAAAANSTNRSVIYTIQNRGPMPLHEVRLLRPALNYFTVSGVLQTPTGWRM
                     ASNNATTGITWESTNATGIPVNGERSFTVVYSNFGAGASLSGPTTFRHRFHLIDDYGGP
                     QIRIDTPMTLVQGTVPDVNRLTGVARDGSVTLAWDNPAVHGGVLILRAEGAPPNLSPTQ
                     GLTYAVGAYLGNAQVVYADDVGATTTFTDTSVTNGTTYYYRVFNSDDLRWYSPGNQPTS
                     QALVATPRARVGAAPLWCYSVGLNASQQPITELGTGIFSAFNDSVVANLTQVTNPSADG
                     AERWRPRPLAGLIGSRFPVVPLHGLSGQYILVGDQGGVASALNAATGQVLWRWDNGGQP
                     IGTIQSFPVTQLFDYANATYRAAHPNRDLVFFATRLADASRNRVVALNAATGAPVWSYQ
                     PGNLGMVAGGMVVDYTTNRLFVATRAHAGSPDTLRVLNTLTGQVLAQLPVGDVELSLVR
                     NAYTNLILVTDSDGFVHGVDAATAQLVWSLPVTTRPAPNTPAFTSFVRPQGLGFVASLA
                     AGRVALYDVSGPAQSPPVLRWSTPIASPSGAFSFNRNGAVRLYVGSSDGQVHQLELLDG
                     SDSGQVSIGGAQRIGTPTIDHTVSRLHVGSEDGRICAFPVPFP"
     gene            13973..14119
                     /locus_tag="OZ403_RS19370"
                     /old_locus_tag="OZ403_19370"
     CDS             13973..14119
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013940359.1"
                     /locus_tag="OZ403_RS19370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OZ403_19370"
                     /product="hypothetical protein"
                     /protein_id="WP_174258830.1"
                     /transl_table=11
                     /translation="MTSDAFQTPPPPDAGPAYEAPAILWEQPFVALAQISQCNIPGESE
                     CIP"
     gene            14107..14958
                     /locus_tag="OZ403_RS19375"
                     /old_locus_tag="OZ403_19375"
     CDS             14107..14958
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011553746.1"
                     /locus_tag="OZ403_RS19375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OZ403_19375"
                     /product="hypothetical protein"
                     /protein_id="WP_268784811.1"
                     /transl_table=11
                     /translation="MHSLTLPREGPTADAALCLRIAGWTGVVEVGDAGLRDSLRRMFSR
                     FVVSPARQGSEVARLVAVAPAQARPAPVIRELPRVHRTEDGTLRLAGEDYDATLSADGL
                     QAHVEGQGRFPVETVLKVMLARALARRGGLLVHGVAVAHQGRAALFTGHSGAGKSTLGG
                     LWAQAGGQVLSDELVAVWPEPGRGWRAAGTPWNVGQAVEAELRVVGTLAWDGVSTWEPQ
                     AAGDVGRMLLVNALLPEATPVGRGGLLGAAGRLLSEVSPVRLVFARDASAAAVIQGALA
                     NG"
     gene            14951..15877
                     /gene="miaA"
                     /locus_tag="OZ403_RS19380"
                     /old_locus_tag="OZ403_19380"
     CDS             14951..15877
                     /EC_number="2.5.1.75"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="miaA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IPPT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011553747.1"
                     /locus_tag="OZ403_RS19380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OZ403_19380"
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="WP_140798503.1"
                     /sec_met_domain="IPPT (E-value: 5.9e-80, bitscore: 267.2,
                     seeds: 863, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGEGGAQRPLLTVIAGPTASGKTALAIALAQRAGGEIVSADSQQV
                     YRHFDIGTAKPSSEELAAVPHHLVSAVDPMEAFSAVEYQRRADAVIAEIAARGRPVFVV
                     GGTGLYLRVLLHGVLEAPGALPELRAELEALAAGEGREAVHRKLAEVDPETAAKLPPQD
                     LVRVIRALEIHAQTGVPASAFRKAHAFAPDRYPFQLYVLSPPRDVLYGLINTRTRMLFE
                     RGLVEETRELLARGYADAAPMRSVGYVQARAVVEGRMTREEAIHDTAQETRRYAKRQLT
                     WFRKEPGAVFLAPPYEAALPRGGCCSP"
     gene            16112..16672
                     /locus_tag="OZ403_RS19385"
                     /old_locus_tag="OZ403_19385"
     CDS             16112..16672
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013940362.1"
                     /locus_tag="OZ403_RS19385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OZ403_19385"
                     /product="HdeD family acid-resistance protein"
                     /protein_id="WP_328285537.1"
                     /transl_table=11
                     /translation="MNSAAWGGPFIMGILMTLLGIVALGAAFFTSLVTAILFGAMLAAA
                     GVMEVISAFRTRKEGGPFWLYLLSGILSVVVGLFVLVYPAAGLGAMTLLLAGYFFASGL
                     FHAVTSVMDRYPRWGWDFFYGAVSIFLGIIVMRQWPISAVWLVGTLVGIGIFFRGVALM
                     AGALSVRKVLRSGGPTTPASISH"
     gene            16789..17715
                     /locus_tag="OZ403_RS19390"
                     /old_locus_tag="OZ403_19390"
     CDS             16789..17715
                     /GO_function="GO:0005254 - chloride channel activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002640058.1"
                     /locus_tag="OZ403_RS19390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OZ403_19390"
                     /product="bestrophin family protein"
                     /protein_id="WP_140798505.1"
                     /transl_table=11
                     /translation="MIDYDPHRWWSYFHYLRGSMVREIVARVLVCVLWAAGVTAVHHHI
                     KPLDIPATVHTLAGISLSLLLVFRTNASYDRFWEGRKLWGGIVNETRNLARASGVFMRR
                     DAALYGTLLRWIIAFPYAAASSLRGERDLGPVASELPRDEADAVLGSQHVPLAVSQKMS
                     VVLDEGRLRGCYPEYVQMQLDQNVQLLIDYIGGCERIHKTPIPFAYMMHLRRALLVYCY
                     TLPFALVDSFGWITVPATFVVAYVFFGIEEIGVEIEDPFGHDDNDLPLERICETIRGNL
                     KALMPGSAEAIHAPVSAVAIPGGGQDA"
     gene            complement(17703..19430)
                     /locus_tag="OZ403_RS19395"
                     /old_locus_tag="OZ403_19395"
     CDS             complement(17703..19430)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011553750.1"
                     /locus_tag="OZ403_RS19395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OZ403_19395"
                     /product="response regulator"
                     /protein_id="WP_140798506.1"
                     /transl_table=11
                     /translation="MMLGNRLATGSRVAVVGGGIAGAGLAASLLFNGRARGLALDVRVY
                     SGGTQERTAPPAVLTPECRSRLAALGCRIPSEWRAHELRGIEIIAEGRRELLSSTPGGL
                     WVVDGWPQGLGGLEQVRDVLATAASAQGARFLPRHVERVERQAPAPDAPASVRGAGSLV
                     VRAQGSGDRFHAVALATGAGPLMGDAFFKGFRPAPTIPAVQARLRHASPRLELAPVARL
                     WIAPLPTVDGLFLLPGANSVYALAFGPAVTPADLCQVLMMAARDGLVEEGFELAALETT
                     RLPYGPGRTLVAPGQIAVGPAAFGHPLQVGLSETLASCSRAAVALLDGGLDTGTLERRY
                     VREGLGEMLEDAAAGARTMTWLRRAGPRSPEAFVKAKGRRTLGGTFGGGVLGLSGPTPI
                     ALLGAARWEGLKELVGSWLRTTVEPVPSVVPELEPDLYYVVDDDPDAREALTALLESTG
                     AKVVSFADELALFCAVARRPPTAILLDVVLHWVDGLRLAEGLKQHPLTRNTRVLVMSGL
                     NRPHVRQRALDAGAEAFLPKPVDPDRLLRILTGRVPVLEPAPHAADDTRELAEDRYAS"
     misc_feature    complement(19572..19581)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     misc_feature    19612..19627
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.17"
                     /tool="antismash"
     misc_feature    complement(19613..19626)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.15"
                     /tool="antismash"
     misc_feature    complement(19948..19962)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.13"
                     /tool="antismash"
ORIGIN
        1 ggagcacggc cacctgtgga taacgcacgg aaggaggccg ccactggaag aggcggacag
       61 cacccccctc cacgcggttc gaggcgaagg tgcccgtgga tgccgcggcg tggaggggtc
      121 ccgtgccggc ggggacctgg accttcaacg tcaccggaac atcggtgccg agcacgatgc
      181 gctcgggcga ccaggacacg gtgacgtcat gctcggccgc caaccccgcc accggcatgg
      241 cgaggaccat caggaggggc agcgcgcgca gtgtcatcgt ccgtgcccct ccatgatgga
      301 tgtgcggccc cggtcaatcc tccgacgcgg ggggcggctc ggcgccgtca gcgggcgccg
      361 gctcggcgct gtcaccgacg ggctggggct tgtccgcggg tccggtcacc tgccggttgg
      421 gcgggttgaa gaccggcttc tccaccgggc caccaccacg gccgtgcacc agcgtcttgg
      481 tgtcggtgcg gaaggtgatg tccaccttgt cgccgcgaac ggccgagacg taacccgtgc
      541 caaaggtggg atgctgaatg acctgatcca ccttgtacgt gtccttcggg ctgtagcggg
      601 gcgcgttggc gacatccttg ccagcgagct gctcctcgaa ggagatgatg atcttctccg
      661 ccttcgcgga cgcgctcgag ctgctggagg acgtgcgcgt ggtgcgggtg gtgctggacg
      721 aagggcgatc cgtcgcgcca ggcgccccgc gataagcgtg atctccgcca cacgtgttgc
      781 agcgcacccg agcaatcttc gttcccacca tcgccaggat ggtgtgcgcg agagtgagct
      841 tgcagcgggt acaaagcgca tccacctcgc cgccgacctt atgagttgcc atgttcgttc
      901 gtctatttct ctgccctgcg ggggacgccg ccgggcatgg gagtaaaggg gcgcggaaca
      961 taacggcatc gcttccaagg gaggaagtgt cttcgtcgct tgcctccccg ggccttgtgc
     1021 cggccaccgg gccgccataa agagtagccc cgaacgcatg accacgcaga cccccagcaa
     1081 gccggcacgc gagcccgggc ccttcaccca ggccgtcacg cgctttggcc agggcctcat
     1141 cgacatcgtc agcaccctgg gcggcatcat caccatgggg ttggacgtgt tccgctggag
     1201 cgtgcggcgc ccctttcggc tggtcaacct cttcgcccag ctggacttcg tgggcgtggg
     1261 gtccatcttc atcgtgtcgc tcaccggcac gttcaccggc atggtcttcg cgctgcagac
     1321 gtccaccgcc tttcggctct tcgacgcgga gagcctggtg gggcccacgg tggctctgac
     1381 gctcacccgc gaactggcgg ccgtgttctc cgcgctgatg gtgaccatgc gcgcaggttc
     1441 tgccatgtgc accgagctgg gcaccatgcg cgtcaccgag caggtggacg cgctggagac
     1501 catggctgtc aacccggtgc agtacctgct ggttccccgg gtgctggccg gcctcttcat
     1561 ggtgccggcg ctcaccatgc tcttcaacac catgggcatg ggcggggcct acgtggtggc
     1621 cgtcgggggc cttggcatct cccccggaac cttcctcacc cggacgcagc agtggctggc
     1681 gcccgaggac atcttccagg gcctgctcaa gggcgccgtg ttcggcctgg cggtgtccct
     1741 catctgctgc ttcaagggct tcaacgcctc gggcggcgcc aagggtgtgg gtcaggccac
     1801 cacggaggcg atggtggcca gcgccctgtc catcttcatc ctcgacttca tcctgggcgt
     1861 cctcttcttc tgatgtcgcc cccggcctcc aacgctccgg cgtccggcac gccgatgatc
     1921 caggtggtcg acctgcacaa gacgttcggc gaccacaagg tgctcaccgg catcaacctc
     1981 accgtgccgg ccggcagcac ctgcgtcatc ctgggcggct caggctccgg caagacggtg
     2041 ctgatgaagc acatgattgg cctgctcaag ccggaccgcg gccaggtcat cgtcgatggg
     2101 gaggacatcg tccccatgag cgtcgagtcg cttcagaggg tgcgcaacaa gttcggcatg
     2161 gtgttccagg ccgccgcgct gttcgactcg atgaccgtct tcgagaacgt ggccttcccg
     2221 ctgcgggagc acacgaagga tccggaagac gtcatccgcc agaaggtccg cgcgcggttg
     2281 gacctgatgg ggctgaagaa ggacgtcgag gatcggttcc ccgcggacct gtccggcggc
     2341 atgcgcaagc gggtgggcct ggcgcgggcc atcgtcatgg acccgaaggt ggtgctctat
     2401 gacgagccga ccaccggcct ggaccccatc accacggact acgtggacga gatgatcctg
     2461 gccgcccaga aggaactggg tgtcaccagc gtggtcatca gccatgacat ctcctctgcc
     2521 ttcaacgtgg cggaccagat tgccttcctc tccaagggcg tcatcgttgc cagcggttcg
     2581 ccggagcaac tccgcgaggc ggatcacccc gcggtgaagg tgttcctgga gacctggttc
     2641 gggaagaact gaccggggcg cggggcggcg ggagggcggg gggccatagg aaaatgtggc
     2701 actcggaatg caaaacgtta gagtcgcgcc ggccggtcgc gctcggagtc acatcaggtg
     2761 aagaagctcg tcacgccctt ccgtgtgggc ctgctggtca tcgcggcggg ggcttttttc
     2821 gtcaccttcg tcctgttcgc tcgcaaaggt ggtttgagcg acagcgaatc cacgagggtg
     2881 tgggcctatt tccgggatgc gtccggcctg gccgtgcgtg ggcgcgtgca gatcgccggt
     2941 atcccggtgg gcgaaatcga cgacatctcg ctcgagggga cccgggcgaa ggtctggttg
     3001 aagatccgca acgacgtgga cctgcgcgag gacgccgtcg tcaccaagcg ctccgaatcg
     3061 ctgctgggtg actacctgct ggacctgaac cccggcacgg agggcgcccc cagcctggag
     3121 acgggtgggc agatccgccg cgtcgtcgac acccagggca tggaggccgt cttcgagtcg
     3181 ctgtcgcaga tcaccgccga catccaggag gtgacggggg cgctgcggga agtgctcggc
     3241 ggtgagcgtg gtgcggggtc gctccagcgc atcgtggaga acctggtgcg gctgtcggac
     3301 tccgtggatg ccacggtccg ccgcaacgcg gaccgcctgg acaccatcgt cggcaacgtc
     3361 gaggccatct ccgcggacgt gcgcggcatc acccagggca accaggcgga aatcacccgc
     3421 atcatcgaca acatcgagtt catcacccgc gacgtgcgcc aggtgctcgg cagcgtgaag
     3481 aacatcgtgg gcacgggtga aggcgacgtg aaggagaccg tcgccagcct caaggagacg
     3541 ctcaagaagc tggacggcac gctgggcaac ctggaggaga tcacccgcaa ggtgaaggac
     3601 ggggagggcg ccgccggcgt gctcctggcc gacgaggccg tgggccgcga gctccgcgag
     3661 acggtgcagg acgtgtcgcg cttcgcttcc cgcctgaccg acctccaggc ggagattggc
     3721 atccagagca cctacctggc cgcgcaggga aattcgaaga acgtcttctc cgtgcggctc
     3781 atccccaagc cggacaagta ctacctgctg gagctggtgg acgaccctcg cggcagcgtg
     3841 acgacggagg tgttgcagac gaacccgccg tccgagggcg accccgtcgt gcagacgcgg
     3901 aaggtgacga aggagagcct caaggtcagc gcgcagttcg ccaagcgctg gtacttcacc
     3961 accctgcgcg tgggccttat cgagtccacc ggcggcgtgg gcgccgacct gcacttcttc
     4021 aacgacgcgc tccggttcca ggtggatgcc ttcaacttcg cggacgacga gctgcgctac
     4081 ccccgcctgc gcgccagcct gcgcgcccag ccgctcgatc acctctattt gatcgcgggc
     4141 atggacgaca tgctcaacgc gcagcagcgg gacctggcga cgcggcgcct ggtggcgggc
     4201 cgcgacttct tcgtgggcgg cggcctgttc ttcacggacg atgatctgaa ggccatcctc
     4261 accttgacag gcattccgac gccctgaacc caccgctcgg cgcttgacgg aaaacgggaa
     4321 acgacgtacc cggcatgggc acggggccca ggggagcgcc gtgcctgatt tcacggcatc
     4381 tccccccagg aagctcgcat gtccctgctc gtcgtcggct ccgttgccct ggactcagtg
     4441 gaaaccccct tcggccagaa ggaggacatc ctcgggggct cggccaccta cttctctacg
     4501 tcggcctcgt tcttcagccc cgcgcgtgtc gtggcggtgg tgggcgagga cttccccgaa
     4561 gggcacctca acttccttcg cggacgggga atcgacctgg agggcctcac ccgggagacg
     4621 ggccgcacct tccgctggaa gggccgctac agctacgagc tgaacgaggc gcagacgctg
     4681 gacacccagc tcaacgtctt ccaggccttc tccccgaagc tgccggagtc gtaccgggat
     4741 acgccctatg tcttcctggg caacatccac ccggaactcc aggcgcaggt gctggaccag
     4801 gtgaaggcgc cgaagctggt ggccgccgac accatgaact tctggatcaa gggcagccgg
     4861 gccgcgctgc tcaagacgct ctcccgcgtc aacctcctgt tcgtcaacga cgcggaggcc
     4921 cgtcagctgg ccggcgagca caacgtggtg aaggccgctc gcgccatcat ggccatgggc
     4981 ccgcagcgcg tggtcatcaa gcgcggtgag tacggcgcgc tcctcttcga ggccgagcac
     5041 atcttcgcgt gtcccgcctt ccccctggcc gaggtcttcg accccaccgg cgcgggggac
     5101 accttcgccg gcggcttcat gggcgctctg gccacctcca atggtgtgtt ggaccaggcg
     5161 ttgctgcgcc gcgccatggt gatgggcagt gtcatggcct ccttcacggt ggagaagttc
     5221 agcctggagc gcctgcgcga ggtgacgcgg ccggagatcc acgcccgctt cgccgagttc
     5281 cggaagctga cccacttcga cgacctgggc cccctggagc gatgaggccg tgggcaaggg
     5341 tggggcgctc caccaccctc gaacttgact gcggaatcag gccgtcccta ggctgcggat
     5401 tcgggtgacg gaagaaggtt ccgggttgag cgaaaaccga aagtccacgc ggattcccac
     5461 ccagcttcgg tgctggtgcg agggtgacaa cgtcacgctc tatgcgcgaa tctcgaattt
     5521 gagcgaggga gggctgttcc tccgcacgag cacgcccctg gcacgagggg cgcgtacggt
     5581 ggtgaagctg tcccccgcgg gccatcagga catccaggcc caggccacgg tggtgtggct
     5641 tcgggaggcg gaggaacgag cgcttcccgc aggcatgggg ttgcgtttcg agtccctgga
     5701 cagcgatacc ctgggacggc ttcgccagat gatttcgcag cagcagcaga accaggtgaa
     5761 ggccggctgg gcgggttgag cccacgccac cggaccgagg ccccgcatgc gtatcgccgt
     5821 catttccgac atccactcca acatcgaggc gctcaccgag gtgctccgcg tcgccgagca
     5881 ccagaaggtg gaccggttcg tctcgctggg ggacatcgtc ggttacgggg cgtcgcccaa
     5941 cccgtgttgt gagttggtgc gttcggtggc ggaagtgacg ctgctgggca accacgacgc
     6001 ggcggtggcg gggcggatgg actattcgta ctactacgac gccgcccggc acgcgctgga
     6061 ctggtccgcc aacgtcctca cggacgagaa catggcctgg ctgcgcagcc tcccgtacac
     6121 gtaccggatt ggcgacgtgg gcttctgcca tggttcgccc atcgacccga aggcgtacga
     6181 gtacatcttc gcgctggagc aggcccggga gctgacgccc tacgtggcgg agttgccgga
     6241 ggtgacgttc atcggccaca gccacctgtg ccgcgccttc gccattggca atggcgaggt
     6301 gaacgacgtg gtggcccaga agttcggcat ccgtcggggc tacaagtaca tcatctccgt
     6361 gggcagcgtg gggcagccgc gcgactacga caaccgggcg tgcttcgtca tctgcgacac
     6421 ggacgcgcgc acggtggagt acatccgcgt cgagtacgac atcgagacgt cggcgcagaa
     6481 gatcttcgac gcggacctgg cgctgaactt cggcaagcgc ctgttcctgg gcgtctgagg
     6541 cccgttccgg ggcacaaaag gcggacaggc gcggggaaat gacataaacc cgtgtcgtgc
     6601 gcaccctggt cctccgagcg tccctcaggc ccctcgtggg cgtcgtctcc gcagtgctgc
     6661 tcacgctggc gcccaccgcc tgccgtcgcg agcctcccgc cccttccgcc gagtacgaag
     6721 aggccgcccg ccgcttccgc gagctgtatg cgcagaagct ggatgacgcc ttcctggatc
     6781 cgcaggtggg agaaatcgag gcaaagctcc agcgcgtccc cgcggacagc ctggacgccg
     6841 agggcgcccg cgagctgctc cagcgcatca aggacggacg gaaccggatg gcggcggccg
     6901 ccaacgagcg ggacgaggcc gtggccagtg cgcgggagct gccgccgggc tcgtacactg
     6961 cgccgtccac cgaggagtcg gcgcgtcccg cggctcccgt ggaagcgccg gatgccgggc
     7021 ctccggatgc cggtgctggc ggtggccccc aggctggcac ggccgcgtcc gagctggtgg
     7081 cgggcttccg ggggtgcttc cagcggggca ctcccatcga tgtgcaggga cggggcatgc
     7141 gggagacctg gcagctcgcc gaccgcaccg cctgccgcct ggagtacccc cagcatcagg
     7201 attcattcct cctgattgaa gaggggaagg tcctcacgct gttacccaag agtgccgtgc
     7261 agaccgtccc cgtcactccc gacggcggtc cggcacccgc gaccgacgcc ggtcgctaga
     7321 accgattcgc cgatatgaac gaccagactt tcatgaagtt gatgcaggtg ttgcccaagt
     7381 ccgcgctctc caccgtggtg gggatggcca cgcgactgcc cgtgcccgcg ccggtgcatc
     7441 aggccgccat gcgcgccttc gccaaggcct acaacgtgga catggaggag gctgagcact
     7501 ccttcgacca ctacccgacc ttcgcccagt tcttcacccg gggcctgaag cccggcctgc
     7561 gtccggtgga cgcgggggag aaggtggtgg tgtccccggt ggatggccgc gtgtcccagg
     7621 tgggctattc ggattacggg cgctgcctgc aggccaaggg catcgagtac acggtggacg
     7681 agctgctggg ggactccgag gccgccaagc ccttccacgg cggcgcctgg acgaccatct
     7741 acctgtcgcc gcgcgactat caccgcatcc acgcgccgct gggtggcacg attacgggct
     7801 acgcgtacat ccccggtgag ttctggccgg tgaaccccgc gtcggtgaag aacaagcagt
     7861 ccctgttctg cgtcaacgag cggctggtga cctacctgga caccgtggcg ggcaagtgcg
     7921 cggtggtgaa ggtgggcgcc acctgcgtgt cgcgcatcaa ggcggcctac gacgaggtga
     7981 cgacgcacac cgggcagccc ggcaaggtgc accgctacgg cgcggccatg ccggtggaga
     8041 agggtgggga gctgggccgc ttcgagatgg gctccactgt catcctcctg ttcgagccca
     8101 agcgcgtcac ctgggacgac agcctccagg aggaagccgt ggttcggctg ggcaagcgaa
     8161 tcggagccat cacgtgagtc agaaggtcgc gggcgtcaag ggcatgaacg atctcctccc
     8221 tggggagatc gagatctggc agcacgtgga ggggctggcc cgcgagctgt tcggccgctt
     8281 cggctacggt gagatccgca cgcccatggt ggaggacacc gccctgttcg tgcgcagcgt
     8341 gggcgaggag accgacatcg tcgggaagga gatgtacacc ttcaacgaca aggcggaccg
     8401 cagcctgtcc ctgcgcccgg aaggcaccgc gcccgcggcg cgcgcgtaca tcgagcactc
     8461 catcgccaac caggagccgc tcacccgctg gttctacaca gggcccatgt tccgctacga
     8521 gcggatgaag acgggccgct accgccagtt ctatcaaatc ggcgcggagg cctacggcgc
     8581 gaaggaaggc gcccaggacg tcgagatgat ggacatggtg gtgcagttcc tggagcggct
     8641 ggggctcaag gacatcaccc tgaacatcaa ctcgctgggg gacgaggcct gccggcccgc
     8701 gtaccacacg aagttggtgg agtacctcca ggcccaccgc gaggaactgt gcgcggactg
     8761 ccagaagcgc atggagaaga accccctgcg cgtcctggac tgcaagaacg agaagtgcca
     8821 ggccatcgcc gcggccggac ccaacgtgct ggagtccctg tgtgagccct gccgcgcgca
     8881 cttcgacgac gtgcagcgga agctgacggc gctgggcatc cggcacgtcg tgaatccacg
     8941 catggtgcgt gggttggact actacacgcg caccgtcttc gagttcatcg cctcgcaccc
     9001 cgcgctgggc accgccagca ccgtgggcgc cggtggccgc tatgacaagc tggtgaagag
     9061 cctgggcggg ccggacgcgc ccgcggtggg cttcgcctgc ggcctggacc ggctggtgct
     9121 gctgctgaag gagagcggcc agcagttcgc cgtgcgccca gacgtcttcg tcgcggtggc
     9181 ggacgcgggc tcgcacgatg ccgccctggt gctggccagc cgcctgcgcc gggagggact
     9241 gcgcgtggag ttcgataccc gcggaggcag cctcaagagc cagatgaagc gcgcggacaa
     9301 gagcggcgcg gacttcaccc tggtgctggg cgaggtcgag cgcaccagcg gccaggcgaa
     9361 gctgaagccc atggccggag gcgagcccat ccccgtcgcg ctcgacgagg tcgccagggt
     9421 ggtgcgggag cggaaggccg ttccggcata gcgtttcgtg ggggcgagaa cagtattccg
     9481 ggcggttctt gccaagtctg agaaactgag gtaggcgcgt aacccctgat aaacgttggg
     9541 ttattgggtc ggcgggaact cgcgggcgca ggtcgggtcg gctagactga cctgcgatgc
     9601 cgcgcgacac ttccaccccc gttgtgcctc cggccctgag ctgggtcccc gtccatgggg
     9661 acagcatgtg gccatcgctg cgctcgggcg accatgccgg cgtggagccg ctggaggggg
     9721 ctccacgacc tggtgacgtc ctgctggcgc gcttcgacca tgccctggtg ctgcaccgac
     9781 tgcggcggtg ggaggccgga gcggtggcgc tgcgaggcga caactcgccc caggaggatc
     9841 caccgctggc gccgacgcgc gtgctggggc gggtgcggcg cgtccgccgg ggcggcgtcg
     9901 tcctggagac ggggtgggac cggggtcccc ggtggctggg ccggctgcgg gtggccgtga
     9961 agtggcgcct ggcggcgttg ctgggccggg gaggtgcgcg atgagcgcgg aattcgcggc
    10021 ggaccatgcg ccgcgctggc gcgagggcgt ctccggccag cgcttcggct cggacttcat
    10081 cgtcctggat gccgagggca acaccctgcg tgggctcaac ggaacggcca ttgaaatctg
    10141 ggaactgtgc gacgggacgc gcacggcgcg ggccctggtt gagcaggtgg cccagcgtca
    10201 cggatgggac gtggagcagg tgctgaccga cacgctcaag ttcttctcgg agctgacccg
    10261 gctggggctc atcgacgagt tggaggaggc gcggtgatgc ggacgcgttt ggcgctcctg
    10321 gcggcggcgg tgatgctggc ctcgtgcacg gagggcgtgg cgccctatgc ccccgttcat
    10381 gcgcccccgg cgcaggagcc ggtggcgccc acggacgtgt tgcccccgcg cgagggttcg
    10441 gaggccaggc cgccgcccgc gccggtggag gagccggaag tgcctccgcc tccgccgccc
    10501 gtggtgccgc ggggctcggc caccgtcatt gacctgggag aggggcgccg gggcttgctg
    10561 tcggtggagc aggtggacgt ggacctgacg gtgagcggcg tgcgtggccg gcacacggtg
    10621 tcagtggagt tcgtgccgcc ttccgggctg ccgtatgagc gccgctcggc ggaggtggat
    10681 tcacgcgtgg acgagtcgcg cacggtgcgc ttctccctgc ccgtggcagg caccgccgtg
    10741 gcgacgtccg gcatgagcgg gacgtggcag gcccggttct tcctcgatgg ggcgccgctg
    10801 acggcggctt ccttcaccct ggatccgtga gggctccatt catgcgtccg ttctccgctc
    10861 ccctcgtcgc cgccgccgcg ctcctggcgc cctcgctggg gtgggcgcag tcgatgtccc
    10921 cgaccgccgt cttgaccacg cagccgcagg gtggggacac ccgcgcgcgg gtggtgatgg
    10981 acgaagcctc cgagctgacg gtcgatgtcc gcaacaacac cttcagttgg tcgccgctct
    11041 tccggcgcat caacgaggtg tggttcgcgc tgcccaatgg ctacatcccg ctcgcgtcca
    11101 tcccgccccc gggatggacg gtggactaca tcgccaatga gcggtgggtc atcttctaca
    11161 atcaggactc ctgcaacggc agcggcgact acggcctggg gcaggacgag tcggcccggt
    11221 tcgttcttcg cgtggttcca ccgacgtcga acaacgacca gaacaacgaa cgcttcatcg
    11281 cgagtcagac gttcgcgcgt gacacgtgcg cggggggcga cttcaccacg tcggtgacga
    11341 cctcggccgc gagctggatt cgctccggcc tgtacaccca ggtggacgtg cgtcctcggg
    11401 tgatgggagt tggcggcgac atcgacgcgc ggatggtggt ggagaaccgg acaggcacga
    11461 accacaacaa caccacggtt gagggaccct ccacgggcgc gggcgccgtc accttccagg
    11521 tggtggacac cgagccgacg ccgttccgca tgaacatcgc cagccggaac gcgggcgttt
    11581 attccgcgag agtgcggacg ggctcggccg gaacgctggt ggcgcgggtg cggggcgtca
    11641 gtgggaacgg caacaccgtg tcgcccgcga tggacgcgcg gatggtcaac gtgggggcgc
    11701 tcccggtggc catggacgtg gacaccgacg acgcgttcaa caatgagctc gtgcgggtgc
    11761 ggctcacggt gaccaacccg acctcgacgg acacgttcct gaacgtgacg ccgcgcgcgc
    11821 ccgtgttcca gggaacggcg gccgcgtcgc tcgtgtcggg gcctgggccc gcgagcgttc
    11881 cccggctgga cccgggcgcc tccgcgcact tcgtctggac gtaccagctc acgggctccc
    11941 cgttcgcgaa ctaccggttc cgggggcagg tggatgccac acgcaacggc gcctctgtga
    12001 catcgaacct ggtggactca aaccaggggc gcatcgtgca gcaccgcgtg cggacgaaca
    12061 tcagcgcggc ggccgccaac tccacgaacc ggtccgtcat ctacaccatc cagaaccggg
    12121 gccccatgcc gctgcatgag gtccggctgc tgcggcccgc gctcaactac ttcaccgtca
    12181 gcggcgtgct gcagacgccc accgggtggc gcatggcgtc caacaacgcc accacgggca
    12241 tcacctggga gtcgacgaac gccacgggca tcccggtcaa cggcgagcgc tccttcacgg
    12301 tggtgtattc caacttcggg gcgggcgcgt cgttgtccgg gcccaccacg ttccgtcatc
    12361 gcttccacct catcgacgat tatggcgggc cgcagattcg catcgacacc ccgatgacgc
    12421 tggtgcaggg cactgtgccg gacgtcaacc gtctcacggg cgtggcgcgc gatggcagcg
    12481 tgacgctcgc ctgggacaac ccggcggtgc acgggggcgt gctgattctt cgcgcggagg
    12541 gcgcgccgcc gaacctctct ccgacgcagg ggctgaccta cgcggtgggg gcctatctgg
    12601 gcaacgccca ggtggtgtac gcggacgacg ttggcgccac cacgacgttc accgatacgt
    12661 ccgtcaccaa cggcaccacg tactactacc gcgtcttcaa ctcggatgac ctgcggtggt
    12721 actcgccggg caaccagccg acgtcgcagg ccctggtagc cacgcctcgg gctcgcgtgg
    12781 gcgcggcgcc gctgtggtgt tactcggtgg gcctgaatgc ctcgcagcag cccatcaccg
    12841 agctgggcac gggcatcttc agcgccttca acgactccgt cgtcgccaac ctcacgcagg
    12901 tcaccaatcc gtcggcggat ggcgcggagc ggtggcggcc tcgcccgctg gcgggcctca
    12961 ttggcagccg cttcccggtg gtgccgctgc atggcctgtc cgggcagtac atcctcgtgg
    13021 gtgaccaggg tggcgtggcc agcgcgctca acgccgccac cggccaggtg ctgtggcgct
    13081 gggacaatgg tggccagccc attggcacca tccagtcgtt ccccgtcacg cagctcttcg
    13141 actacgcgaa cgccacgtac cgggccgcgc accccaaccg cgacctcgtc ttcttcgcca
    13201 cgcggctggc ggacgcttcg cgcaaccggg tggtggccct gaatgccgcc accggcgcgc
    13261 cggtttggag ctaccagccc gggaatctgg gcatggtggc gggtggcatg gtggtggact
    13321 acaccaccaa ccggctcttc gtggcgacgc gcgcgcatgc gggctcgccg gacacgcttc
    13381 gggtgctgaa cacgctgacg gggcaggtgc tggcgcagct cccggtgggc gacgtggagc
    13441 tgagcctggt tcgcaatgcg tacaccaacc tgattctcgt gacggacagc gatggcttcg
    13501 tgcacggcgt ggatgccgcc acggcgcagc tcgtgtggag cctgccggtc accacgcgcc
    13561 cggcgccgaa cacgccggcc ttcaccagct tcgtgcggcc ccagggcttg ggcttcgtgg
    13621 ccagcctcgc ggctggccgg gtggcgctgt acgacgtgtc ggggcccgct cagtcgccgc
    13681 cggtgctccg gtggagcacg ccgattgcgt ctccctctgg cgccttctcc ttcaatcgga
    13741 atggcgccgt gcgcctctac gttggcagct ccgacggaca ggtccaccag ttggaactgc
    13801 tggatggctc cgactccggt caggtctcga ttggtggtgc gcagcgtatc gggactccca
    13861 ccatcgacca cacggtgagc cgcctccacg tgggctccga agatggtcgc atctgcgcgt
    13921 tcccagtccc gttcccttga agaacgtccc ttcttcctcg ctcgcacacc ccatgacttc
    13981 ggacgccttc cagacgccgc cccctcctga cgccggccct gcctatgagg cgccggccat
    14041 tctctgggag cagcccttcg tggcactggc gcagatttcc cagtgcaaca tccccggtga
    14101 gtcggagtgc attccctgac ccttccgcgg gaaggcccca cggcggacgc ggccctctgc
    14161 ctgcgaatcg ccggttggac gggagttgtg gaagtcggcg atgcgggcct gcgagactcg
    14221 ctccggcgca tgttctcccg gttcgtggtg tccccagcgc gacagggcag tgaggtggct
    14281 cggctcgtgg ccgtggcccc cgcccaggcg cgtcctgctc ccgtcattcg cgagctgcca
    14341 cgggtccacc gcacggagga cggcacgctg cgcctggccg gcgaggacta cgacgcgacg
    14401 ctttccgccg acggcctcca ggcccacgtt gaggggcagg gacggtttcc cgtggagacg
    14461 gtgctgaagg tgatgcttgc ccgggcgctg gctcggcgtg gcgggctgct ggtgcatggc
    14521 gtggcggtgg cgcaccaggg ccgggccgcg ctcttcacgg ggcactcggg ggcggggaag
    14581 agcacgctgg ggggcctttg ggcgcaggcg ggcgggcagg tgttgtccga tgagttggtg
    14641 gccgtgtggc cggagccggg ccgtgggtgg cgggcggcgg ggactccctg gaacgtgggg
    14701 caggccgtcg aggcggagct gcgcgtggtg gggacgttgg cgtgggacgg cgtgtcgacg
    14761 tgggagccgc aggccgctgg cgacgtcgga cggatgctgc tcgtcaatgc cctgctgccc
    14821 gaggcgacgc ccgtggggcg gggtgggctg cttggcgcgg cgggacggtt gctgtcggag
    14881 gtttcgcccg tgcggttggt gttcgcgcgt gatgcgtccg cggcggcggt gattcaggga
    14941 gcgttggcga atgggtgagg gtggagcgca gcggccactg ttgaccgtga ttgccgggcc
    15001 gacggcgtcg gggaagacgg cgctggcgat tgcgctggct cagcgtgctg gtggcgaaat
    15061 tgtcagcgcg gactcgcagc aggtgtaccg gcacttcgat atcggcacgg cgaagccctc
    15121 ctcggaggag ttggccgcgg tgcctcatca cctggtgtcc gccgtggacc cgatggaggc
    15181 gttctccgct gtcgagtacc agcgccgtgc ggacgctgtc atcgcggaga ttgccgcacg
    15241 cggccggcct gtcttcgtcg tgggcggcac cgggctgtac ctgcgcgtgc tgcttcacgg
    15301 tgtgctcgag gcgcccgggg ccttgccgga gttgagggcg gagttggagg cgctggcggc
    15361 cggtgagggg cgcgaggcgg tgcaccggaa gctggcggag gtggacccgg agacggcggc
    15421 gaagcttcct ccgcaggacc tggtccgcgt catccgggcg ctggagattc atgcgcagac
    15481 gggcgtgcct gcctcggcgt tccggaaggc ccatgccttc gcgccggacc gttatccctt
    15541 ccaactgtac gtcctgtcgc caccgcggga cgtgttgtac gggctcatca acacgcgcac
    15601 gcggatgttg ttcgagcgtg ggctcgtcga ggagacccgc gagttgctgg cgcgagggta
    15661 cgccgatgcg gcgcccatgc gcagcgtggg ctacgtgcag gcgcgcgccg tcgtcgaggg
    15721 tcggatgacg cgcgaagagg ccatccacga caccgcgcag gagacgcgcc gctacgccaa
    15781 gcggcagttg acgtggttcc ggaaggagcc cggtgctgtc ttcctggctc ccccgtacga
    15841 agcggcgctt ccgcgcggcg gctgttgctc accctgacgg cccaagggcc ggggcgggcg
    15901 agggacggag cggcgtcagc gagcgttgtc ggccccaacg cggtggccca tgttcggcga
    15961 tggatgtgcc gggttccttt gtcgcctgcc gacaggcggg cgagacgcga ggcggctcgg
    16021 cctccgaagt gcactcgctt cgggagcagt caccatggcc ttcaccgatg aacgcaaacc
    16081 ggaaatcctg acccctgaca cgaggccgag ggtgaactcg gcggcctggg gtggcccctt
    16141 catcatgggg attttgatga cgctgctggg gattgtcgcg ctgggggccg ccttcttcac
    16201 cagcctggtg acggccatcc tcttcggcgc gatgctggcc gcagccggcg tcatggaagt
    16261 catctccgcc ttccggacgc gcaaggaggg cgggccgttc tggttgtacc tgctcagcgg
    16321 catcctctcc gtcgtcgtgg gtctgttcgt cctcgtctac ccggcggcgg gactgggtgc
    16381 catgacgctg ctgctggcgg gctacttctt cgccagcggg ctcttccacg ccgtcacctc
    16441 ggtgatggac cgctatcccc ggtggggctg ggacttcttc tacggcgccg tgtccatctt
    16501 cctgggcatc atcgtgatgc ggcagtggcc catctccgcc gtctggctgg tgggcacgct
    16561 ggtgggaatc ggcatcttct tccggggcgt ggcgctgatg gcgggcgccc tctccgtgcg
    16621 gaaggtgctc cgctcgggcg gtccgacaac gcctgcctcc atctcccact gacgggcagg
    16681 cggccaaggg caccggctcc cgtccagggc ggacacatcc cacgtgtccc cctggattgg
    16741 cgcttgccat gccccgcgca ggcgcggcag cgtacgcgcc ctgcgaccat gatcgactac
    16801 gacccgcacc gttggtggag ctacttccat tacctccgcg gttccatggt ccgcgagatt
    16861 gtggctcggg tcctcgtctg tgtgttgtgg gccgcgggcg tcaccgcggt ccatcatcac
    16921 atcaagcccc tggacatccc ggccacggtg cacacgctgg cgggcatctc gctcagcttg
    16981 ttgctcgtct tccggaccaa cgcctcctat gaccgcttct gggaaggccg gaagctgtgg
    17041 ggcggcatcg tcaacgagac gcgcaacctg gcccgtgcat ccggcgtctt catgcgtcgg
    17101 gacgccgcgc tctacggcac cctgctgcgg tggatcatcg ccttccccta tgccgccgcc
    17161 tcgtcactgc gaggggagcg cgacctgggc cccgtcgcct ccgagctgcc gcgcgacgaa
    17221 gcggacgcgg tgctgggcag ccagcacgtc ccgctcgcgg tgtcgcagaa gatgtccgtc
    17281 gtgctcgatg agggccggct gcggggctgc taccccgaat acgtccagat gcagctcgac
    17341 cagaatgtcc aactgctcat cgactacatc ggtggctgcg agcgcattca caagacgccc
    17401 attccgttcg cctacatgat gcacctgcgg cgagcgctgc tcgtctactg ctacacgctg
    17461 ccgttcgcgc tggtggattc gttcggctgg ataacggtgc ccgccacgtt cgtcgtcgcc
    17521 tacgtcttct tcggcatcga ggagattggc gtggagatcg aggacccgtt cggccacgac
    17581 gacaacgacc tgccgctgga gcggatctgc gagacgatcc gcggcaacct caaggcgctg
    17641 atgcccggga gcgccgaggc catccacgcc ccggtctccg cggtcgccat ccccggcggt
    17701 ggtcaggacg cgtagcggtc ctcggccagc tcgcgcgtgt cgtccgcggc gtgcggcgcg
    17761 ggctccagaa cggggactcg gccggtgagg atgcgcagca gccggtcagg gtccacgggc
    17821 ttgggcagga aggcctccgc ccccgcgtcc agggcccgct gccggacatg cggccggttg
    17881 aggccactca tcaccagcac gcgggtgttc cgggtgaggg gatgctgctt caggccctcg
    17941 gccagccgca ggccatccac ccagtgcagc accacgtcca ggaggatggc cgtgggcggc
    18001 cgccgggcca ccgcgcagaa gagggccagc tcgtcggcga aagacaccac cttcgccccg
    18061 gtgctctcca gcagcgcagt gagcgcctcg cgtgcgtccg ggtcgtcatc cacgacgtag
    18121 tagaggtccg gctccaactc cggcaccacc gaggggactg gctccaccgt ggtgcgcagc
    18181 caggagccga ccaactcctt gagtccctcc cagcgcgcgg cgccaaggag cgcgatgggc
    18241 gtggggccgc tcaggcccag caccccgccg ccgaaggtgc cacccagcgt ccgtcgcccc
    18301 ttcgccttga cgaaggcctc cggcgagcga gggcccgctc ggcgcagcca ggtcatcgtc
    18361 cgggctcccg cggcggcgtc ctccagcatt tcgcccaggc cttcgcgcac gtagcggcgc
    18421 tccagggtgc ccgtgtccag cccgccgtcg agcagcgcca ccgccgcgcg gctgcacgaa
    18481 gccagtgtct ccgacaatcc cacctggagt gggtggccga aggccgcggg ccccaccgcg
    18541 atctgccccg gcgccaccag cgtccggccc ggtccgtagg gcaggcgggt ggtctccagg
    18601 gccgccagct cgaagccttc ctccaccagg ccgtcgcgcg cggccatcat cagcacctgg
    18661 cacaggtccg cgggcgtcac cgccggcccg aaggccagcg cgtacaccga gttggcgcca
    18721 ggcagcagga acagaccatc caccgttggc aggggcgcaa tccacagccg ggccaccgga
    18781 gccagctcca gccgaggcga agcgtggcgc aggcgagcct gcaccgccgg gatggtgggg
    18841 gcagggcgga agcccttgaa gaaggcgtca cccatcagcg gcccggcgcc ggtggccagc
    18901 gccaccgcat gaaagcgatc accactgccc tgggcgcgca ccaccagcga gcccgcgccg
    18961 cgcacggagg cgggcgcatc cggcgcgggg gcctgccgct ccacgcgctc gacgtggcgg
    19021 ggaaggaagc gggcgccctg ggcgctggcc gcggtggcga gcacatcccg cacctgctcc
    19081 aggccgccca gcccctgggg ccagccgtcc accacccaga ggccaccggg cgtggaggac
    19141 agcagctcgc gccggccctc ggcgatgatt tcaatgccgc gcagctcatg ggcgcgccat
    19201 tcggagggaa tgcggcagcc cagcgcggcc aggcgtgagc ggcattccgg cgtcagcacc
    19261 gccggcggag cggtgcgctc ctgcgttcct ccggagtaga cgcgcacgtc cagcgccagc
    19321 ccgcgagccc tcccgttgaa aaggagtgag gcggcaagcc ccgctccggc aatgccgcct
    19381 cccaccaccg ccaccctcga acctgtcgcc agtctgttcc ccagcatcat ccgcgccctc
    19441 gctgctgccc cgccgttgcc tgcctcaccg cgccccgttc agtgccgctg cgccggaggc
    19501 gaattcgcgg gccggccaaa cacgacgacc cgatcccgcc cctcgcgctt cgcctcgtag
    19561 agggccgcgt ccgccgcctt catcagcgac tcggtgtcct cgcggggccc ttcgaaggta
    19621 tggtcggcga tgcccacgct cacactcagt ccgaaggggg cagggcggcc gtcgctcttc
    19681 tggacgccga cggcgcgcag cccggtgcgg atgcgctcgg cgaagacggc tgcttccaac
    19741 gccgtctggt gcggcagcag cgcgacgaac tcgtctccac cgaagcgggc cgcgaagtcc
    19801 gactcacgca gctcgtgctt caactgggtg gccagcgcga gaatcgcccg gttgcccacg
    19861 tcatggccca tgccgtcgtt gatagccttg aggtggtcca ggtcgatgat gacgacgctc
    19921 agcgggtact ggtagcgctg ggcccggcgg aactcttctt ccatccggat ggtcagcgcc
    19981 cggaagttgg ccagccccgt gaggccgtcc gtctgcgcca ggacctgcag ccggcgctgc
    20041 tgctcgctct ggcgcagcgc ccggtcgata cgggccagca gctcccgcgc gctggccggc
    20101 ttgtggatga agtccacggc gcccatctcc aggcagcgct ccagcgtggc ctcgtccgcg
    20161 tcgcccgtca ggaagatgac gggcaccgcc tccgtgcgcg actcgcgctg gagcatctcc
    20221 agcaccgcga gcccgtctcc gctgggaagg aacctatcca ggaggatgag gtccgggcgg
    20281 tgctctcgcg ccagctc
//
