LOCUS       NZ_CP113950            23321 bp    DNA     circular CON 28-JAN-2024
DEFINITION  Myxococcus sp. NMCA1 chromosome, complete genome.
ACCESSION   NZ_CP113950
VERSION     NZ_CP113950.1
KEYWORDS    RefSeq.
SOURCE      Myxococcus sp. NMCA1
  ORGANISM  Myxococcus sp. NMCA1
            Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
            Myxococcaceae; Myxococcus.
REFERENCE   1  (bases 1 to 9502182)
  AUTHORS   Ahearne,A., Stevens,C. and Phillips,K.
  TITLE     Minimal conservation of predation-associated metabolite biosynthetic
            gene clusters underscores biosynthetic potential of Myxococcota
            including descriptions for ten novel species: Archangium lansinium
            sp. nov., Myxococcus landrumus sp. nov., Nannocystis bai
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9502182)
  AUTHORS   Ahearne,A., Stevens,C. and Phillips,K.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-NOV-2022) Biomolecular sciences, University of
            Mississippi, Faser Hall 407, Oxford, MS 38655, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 10.1.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200x
            Sequencing Technology             :: PacBio Sequel II
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/28/2024 03:49:16
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,878
            CDSs (total)                      :: 7,793
            Genes (coding)                    :: 7,662
            CDSs (with protein)               :: 7,662
            Genes (RNA)                       :: 85
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 56 of 131
            Pseudo Genes (incomplete)         :: 88 of 131
            Pseudo Genes (internal stop)      :: 13 of 131
            Pseudo Genes (multiple problems)  :: 24 of 131
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:28:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3359010
            Orig. end                         :: 3382331
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP113950.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23321
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="6"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..23321
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23321
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13321](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13321)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            complement(646..1533)
                     /locus_tag="OZ403_RS14485"
                     /old_locus_tag="OZ403_14485"
     CDS             complement(646..1533)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002635001.1"
                     /locus_tag="OZ403_RS14485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OZ403_14485"
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="WP_268784435.1"
                     /transl_table=11
                     /translation="MPGSRRPSHARAILFGRNPTQDDPFDVEADAAEALGVDTYQADLG
                     ALLSGNAEQALSTLPERGRLRLLYRGWMLTEEEYMALDEAVSALGHRLTTTPEQYAAAL
                     YLPNWYPQLSRYTARSVWTEGMDAAEAWHAAQALGSQPWLVKDHVKSAKERWDEACFIP
                     EGTTQARFEQICANLVDERGDRFERGLVVRKFLPFKTYGRTPAGPAHLEFRLFFGSGRL
                     LAAEPYHELDVDVPDFTGFEPLARRIDSPFLTLDVAMLQDGGWAVVEVNDGGVSGLPPG
                     LDPRTLFEALLDPR"
     misc_feature    1547..1561
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.4"
                     /tool="antismash"
     gene            complement(1681..3495)
                     /locus_tag="OZ403_RS14490"
                     /old_locus_tag="OZ403_14490"
     CDS             complement(1681..3495)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013939435.1"
                     /locus_tag="OZ403_RS14490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OZ403_14490"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_237078289.1"
                     /transl_table=11
                     /translation="MRIPHALSLGAAALLALSAQAAAPSRPSPALPPGYWPEEKVAEVL
                     AKTQEVRLSPDLSRLTPDEQAAVKDLLEVGAIFQGLYESSRHHQALPALAKLEALDKKL
                     GGPKRTQDLLALYRLYQGPIASTLSNAREAFLPVDAQVAARNVYPVDVTRAEVDAFLAA
                     NPGERQSLLSEKTVVRRATAANLRQDVKVLQTHPVLDTLHPGLRQALQAKAKRPDAKAL
                     YAVPYAVAYGPELVKAYGLVMRAAQRLEASDVELARYLRNRARDLLTNDYESGDAAWVT
                     GRFQKLNVQLGAYETYDDALFGVKAFHSLSVLLSNESATQELRKRLGGLQAVEDALPYA
                     AKKRVREDIPVGVYDVIADFGQSRGTNTASILPNDALAARRYGRTILLRENIMRNPDLF
                     ASDERIWRAAVADAHVRELVSEGNFQRTLWHEVGHYLGPDRDQKGRTLDDALEDYAGAV
                     EEMKADLVSLFSLHDFHKKGTLDAAGLRAVQASGIRRTLQNVRPREDQPYQRMQLVQFN
                     WFLEHGLLQADPQTARLSIQYDKYPAVVTSLLEKVLALQHGGDKAATAAFFQRWSAWTP
                     ELHEKLAARIREAQGARFRLVRYDALGD"
     gene            3685..4830
                     /locus_tag="OZ403_RS14495"
                     /old_locus_tag="OZ403_14495"
     CDS             3685..4830
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013939436.1"
                     /locus_tag="OZ403_RS14495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OZ403_14495"
                     /product="proprotein convertase P-domain-containing
                     protein"
                     /protein_id="WP_237078290.1"
                     /transl_table=11
                     /translation="MDAEHEAVELGTQTQALATGTPAGEGVLSFLNEYSISLSVLDQEV
                     PLNALAAQALIDFREGPDGVLRTGDDRRFVSIEQVDAVPYVGPAALAALEAYAKGTGRV
                     ELPVDGHVGTFHGVAFNMAEARRAIHAANTESASNLQTLFGIPAAAVQSLVAARPILHM
                     VQLSRLTNVNAVTMGQLKAHTQQAAEGDPCTGPGICQPGLICEGRPGDGSSPYGRCVDA
                     SYLSGNGDVCSRFVACPSEKLICIGLASGWVEGYCAPAWMGASFIEYSDLRLQSTNPLV
                     TAPLTVVGLATVPMDINVELDVVHTAPHRLVLTLEDPGGETALLWDGPNEGTPPSRIVV
                     TRGIPRDGVINGRWKLHVANPSGVGSGTLRSWTLKLTSRYD"
     gene            complement(4893..6338)
                     /locus_tag="OZ403_RS14500"
                     /old_locus_tag="OZ403_14500"
     CDS             complement(4893..6338)
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105: amidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011552913.1"
                     /locus_tag="OZ403_RS14500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OZ403_14500"
                     /product="amidase"
                     /protein_id="WP_268784436.1"
                     /transl_table=11
                     /translation="MNLDDYSRFDAVGLAELVRRKEVTPEELLRVAVEAIHRVNPAINA
                     VIDTRDTQAHEALKQGLPDGPFRGVPFLIKDIGVHAAGVPTDLGSRLTQGTVFPYDSAL
                     MARYRRAGLVLLGRTNAPEFGNNATTEPLLHGPTRNPWDVGRSPGGSSGGSAAAVAAGI
                     VPVAHGNDGGGSLRIPASLCGVFGLKPTRGRNSLGPNSGDFICGMGIEHVLSRTVRDSA
                     AVLDATQGPEAGDPYFAPPPRRPYLEEVGRTPGRLRIALMTASPMGGPVSPQCIEAARL
                     AARLCEELGHDVTEDAPAHDGLLLHEAVTTVWSATIASLVAMASHYSGREAEPDSLEAT
                     TWAVVRHGQALTATDLQRALGVFNFVSRKVGLFFEKYDVLLSPTVAAPPFPLGLLDANA
                     PRTAREWYDHAFGHCPFTALFNVTGQPAMSVPLHWSAEGLPIGVQFAGRYADEATLFQL
                     AGQLEQARPWAQRRPPVHVTRPA"
     gene            complement(6426..8627)
                     /locus_tag="OZ403_RS14505"
                     /old_locus_tag="OZ403_14505"
     CDS             complement(6426..8627)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011552914.1"
                     /locus_tag="OZ403_RS14505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OZ403_14505"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_268784437.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.1e-35, bitscore:
                     121.2, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAEAPQQPQRRWRLGLRKRVPEVRQMTMTDCGAACLAMVLAYHG
                     REMSLEAVRELTGPGRDGASAKSLKAAAQKLGLRVRAISVDLDRLPFLPPATILHWRFT
                     HYVVFERLGRGWVEVVDPDQGRRRVSMEQFSQCFTGVALLMEPSEDFQPGQSRRGPYRY
                     LVPLVKRQAGTLAKVLALSAVLQVLTLAVPMLTGMVVDRVVPRQDYSLMGVLSAALAGV
                     LLFELLSSVVRGQLLVELRTRLDSQMTQGLLDHLVSLAYPFFQLRPAGDLLTRLGSQQA
                     IRDLLSTGLLSSALDGALVLLYLGLLLVADASLGLLVVGLGLLQVLVFALPRAKQRSQL
                     SRSLDMGVRSQSYLMAMLSGMQTLKAFGVEGRMVGSYSNLYVDLLNVELERGRLSAWLD
                     ALTGTLRRVSPLVLLCVGAWRVLDGAVSLGQMLSINALATALLVPLSNLLGTGGQLQFL
                     STYLERINDVLDTPPERDAAHQGRAPTLRGAVNLEDVRFRYNPHSAWVVQGVSVSVEPG
                     QMVALVGRSGAGKSTLAHLLLGLYLPTSGHVRYDGAELGELDLRAVRNQLGVVLQDASF
                     FNASLRENITLSDPDLDMDRVVEAAKLAHIHDDIMAMPMQYDTPLTDRGLSMSGGQRQR
                     LALARALVRRPAILLLDEATSALDATTEAHVQQALASLKCTRVVIAHRLSTVRNADTIL
                     VMEAGRVVEVGRHQELLERQGAYASLVNAQREERTQAVG"
     gene            complement(8624..8839)
                     /locus_tag="OZ403_RS14510"
                     /old_locus_tag="OZ403_14510"
     CDS             complement(8624..8839)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011552915.1"
                     /locus_tag="OZ403_RS14510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OZ403_14510"
                     /product="hypothetical protein"
                     /protein_id="WP_140790400.1"
                     /transl_table=11
                     /translation="MQPPTDGRPSIFRKEALAHYQRVVQDEGDLLRIGGRWTRWTFALL
                     FVFGLALALGVLAWPALIAPEGNVSP"
     gene            complement(8934..9146)
                     /locus_tag="OZ403_RS14515"
                     /old_locus_tag="OZ403_14515"
     CDS             complement(8934..9146)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011552917.1"
                     /locus_tag="OZ403_RS14515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OZ403_14515"
                     /product="mersacidin/lichenicidin family type 2
                     lantibiotic"
                     /protein_id="WP_140790402.1"
                     /transl_table=11
                     /translation="MSQKKEHILRAWRDPEYFNSLSSEERASLPANPAAELELSDEVLE
                     NISGADTCEQFGSYYCTPCPPYHCL"
     CDS_motif       complement(8997..9146)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MSQKKEHILRAWRDPEYFNSLSSEERASLPANPAAELELSDEVLENISGA"
                     /locus_tag="OZ403_RS14515_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(8934..8996)
                     /prepeptide="core"
                     /locus_tag="OZ403_RS14515_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-1.40"
                     /molecular_weight="2273.5"
                     /monoisotopic_mass="2271.9"
                     /core_sequence="DTCEQFGSYYCTPCPPYHCL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSQKKEHILRAWRDPEYFNSLSSEERASLPANPAAELELSD
                     EVLENISGA"
                     /leader_location="[8996:9146](-)"
     misc_feature    9119..9133
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.85"
                     /tool="antismash"
     gene            complement(9177..9392)
                     /locus_tag="OZ403_RS14520"
                     /old_locus_tag="OZ403_14520"
     CDS             complement(9177..9392)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011552917.1"
                     /locus_tag="OZ403_RS14520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OZ403_14520"
                     /product="mersacidin/lichenicidin family type 2
                     lantibiotic"
                     /protein_id="WP_140790404.1"
                     /transl_table=11
                     /translation="MSQKKDHILRAWRDPEYFNSLTAEERAALPANPAAELDLGDDVLE
                     SITGGCGCKPGQSSAICTPCPPYHCL"
     CDS_motif       complement(9243..9392)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MSQKKDHILRAWRDPEYFNSLTAEERAALPANPAAELDLGDDVLESITGG"
                     /locus_tag="OZ403_RS14520_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9177..9242)
                     /prepeptide="core"
                     /locus_tag="OZ403_RS14520_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-2.00"
                     /molecular_weight="2111.5"
                     /monoisotopic_mass="2109.9"
                     /core_sequence="CGCKPGQSSAICTPCPPYHCL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSQKKDHILRAWRDPEYFNSLTAEERAALPANPAAELDLGD
                     DVLESITGG"
                     /leader_location="[9242:9392](-)"
     gene            complement(9483..9698)
                     /locus_tag="OZ403_RS14525"
                     /old_locus_tag="OZ403_14525"
     CDS             complement(9483..9698)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002635009.1"
                     /locus_tag="OZ403_RS14525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OZ403_14525"
                     /product="mersacidin/lichenicidin family type 2
                     lantibiotic"
                     /protein_id="WP_140790406.1"
                     /transl_table=11
                     /translation="MSQKKDHILRAWRDPEYFNSLSSEERASLPANPAAELELGDDLLE
                     VITGGDFCLPGQSSPQCTPCPPRHCF"
     CDS_motif       complement(9549..9698)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MSQKKDHILRAWRDPEYFNSLSSEERASLPANPAAELELGDDLLEVITGG"
                     /locus_tag="OZ403_RS14525_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9483..9548)
                     /prepeptide="core"
                     /locus_tag="OZ403_RS14525_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-2.80"
                     /molecular_weight="2266.6"
                     /monoisotopic_mass="2265.0"
                     /core_sequence="DFCLPGQSSPQCTPCPPRHCF"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSQKKDHILRAWRDPEYFNSLSSEERASLPANPAAELELGD
                     DLLEVITGG"
                     /leader_location="[9548:9698](-)"
     gene            complement(9789..10004)
                     /locus_tag="OZ403_RS14530"
                     /old_locus_tag="OZ403_14530"
     CDS             complement(9789..10004)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002635009.1"
                     /locus_tag="OZ403_RS14530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OZ403_14530"
                     /product="mersacidin/lichenicidin family type 2
                     lantibiotic"
                     /protein_id="WP_140790406.1"
                     /transl_table=11
                     /translation="MSQKKDHILRAWRDPEYFNSLSSEERASLPANPAAELELGDDLLE
                     VITGGDFCLPGQSSPQCTPCPPRHCF"
     CDS_motif       complement(9855..10004)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MSQKKDHILRAWRDPEYFNSLSSEERASLPANPAAELELGDDLLEVITGG"
                     /locus_tag="OZ403_RS14530_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9789..9854)
                     /prepeptide="core"
                     /locus_tag="OZ403_RS14530_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-2.80"
                     /molecular_weight="2266.6"
                     /monoisotopic_mass="2265.0"
                     /core_sequence="DFCLPGQSSPQCTPCPPRHCF"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSQKKDHILRAWRDPEYFNSLSSEERASLPANPAAELELGD
                     DLLEVITGG"
                     /leader_location="[9854:10004](-)"
     gene            complement(10001..13321)
                     /locus_tag="OZ403_RS14535"
                     /old_locus_tag="OZ403_14535"
     CDS             complement(10001..13321)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011552918.1"
                     /locus_tag="OZ403_RS14535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OZ403_14535"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_268784438.1"
                     /sec_met_domain="DUF4135 (E-value: 9.6e-110, bitscore:
                     366.1, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.3e-57, bitscore:
                     194.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEITQRQDEATPGANAPSRFARWARATTLAERAVFTLKTSTTQPD
                     ASAAARKRLDAWRQQEPFGQADWWQRRLQSSGLTETELLMLLEVPAEAPWTTPAEVPGW
                     VQVLERAYAEPSHAPVIWPERTEGPDRSAFLPLVEPLVSRAVTQLTAALKPLKHAAPGL
                     DLEPSVVVSTMLGHLPQVLAPALGRAMVVELHAAQLEGLLAGDTPEARFQDFTKRLRQP
                     RFALDILERYPVLARCVVLRIAEWESNCLGLMKRLTRDAPLLWQRFNAGQSPGALVEAR
                     GGFSDPHRGGQGVFILRFESGLRIVYKPRSLGAEAGLQQLLTWLNARGATPVMKGAEAL
                     DRGEYGWMEYVAPAPCASTEEVRRFYERQGAYVALMHALDGTDLHFENLIAAGEHPVLV
                     DVETLFHPLSGTRTLRDSEHAVEAPPVSVLRSGLLPQQFWGTRKKAGVDLSGLGARAGQ
                     LTPQAYLMTAERGTDRMRFERRPVELPGSNNLPRLEGETAPVLAYRDALADGFTRMYSL
                     LLEHREALLAEDGPLAAFAPVPMRILFRNTAVYGALLFESYHPHVLTDGLERQRFFDHL
                     WRAVVPVPDFAALVPLETEQLERGDLPYFTARADSKDLEAGSGQRLPDFFQETGMARVR
                     RRLKGLSPEDQTRQRWVLERSLDVLLLSSQTVARPTYPFREHTQPGLRDALLAEARRAG
                     ERLLPLAFERRDEAHWLGLDAGDGGWRLGSPGPDVFQGRAGIALALGYLGDVTQDARFT
                     RLARATLRTQARLLAEEPAGVVGLGILNGWGGILYALTHLGVLWKDDALLDEAAGYVRR
                     LRPLVEKDTVLDVGAGAAGCLLALLVLGEHRPSDTLWATVDACGQRLLETSTPQARGAA
                     WICEAAGNRYLAGMAHGAAGISLALLRLFARTGDTRLRDAAVAGMEFERGLYTPEERNW
                     PDLRVGAKELAAAEGAEHFLWAWCTGAPGIGLARLSGLPFVDDAAVREEIAIALDSTLA
                     RGFGRNHGLCHGDLGNADFLLEAAATLGDSKLQERTNAVAGGILRGISEHGYLFGLQGS
                     TETPGMMVGLAGIAYGLARLAMPERLPSLLTVAPPRIVRGEGLGTPDGRPSSRDQEQS"
     misc_feature    complement(13276..13291)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.9"
                     /tool="antismash"
     gene            13457..15052
                     /locus_tag="OZ403_RS14540"
                     /old_locus_tag="OZ403_14540"
     CDS             13457..15052
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012935.4"
                     /locus_tag="OZ403_RS14540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OZ403_14540"
                     /product="GMC family oxidoreductase"
                     /protein_id="WP_268784439.1"
                     /transl_table=11
                     /translation="MREGGSDLYDALIIGSGAGGGPLALKFSQAGLRVLVLERGPRHSP
                     REYAHDATGLGPQDLIPRVEDDPHTVVTRKTSVPLRTALGWTASCVGGGTVHMGGYFYR
                     FHPDDLRMRSRFGDYEELADWPYDYAALEPWYAVAEQEVGVSGLAGVNPFEGPRSTPFP
                     LPPLDAHPLAAALEEACARRGLHAFSTPRSINSRPYQGRPACAYCLECSGLGCPVGARG
                     SSQAALLPRAEATGHCEVRARCHVREVTVGPDGRATGCVYLDAEGQEHRVTARVVCVCC
                     SSVESARLLLLSRSPRFPNGLANGSGRVGRHLQFHAVTMAQARLPRDRLPGALLENPHP
                     FIGRSVMDHYFLPDGVSDLPKGGILRFGRGPPVPESRDGAKASDVLFCEVFHDFLPNAG
                     TFVELDPEVKDRWGLPVARIHLDRPRHHVRAGQWLLARTFELFRDLGAEECVPLIVGGT
                     SSYLVQGTCRAGDDPETSVLDGHCQTHEVDNLFVVDGSFMPTSGGAAPTLTILANSFRS
                     ADHIVRRFQAGDFA"
     gene            15144..18095
                     /locus_tag="OZ403_RS14545"
                     /old_locus_tag="OZ403_14545"
     CDS             15144..18095
                     /EC_number="3.6.4.-"
                     /GO_function="GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013939442.1"
                     /locus_tag="OZ403_RS14545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OZ403_14545"
                     /product="DEAD/DEAH box helicase"
                     /protein_id="WP_140790413.1"
                     /transl_table=11
                     /translation="MSATAQLLETVRKEAKPGIWSNGVNLARSGAVVLQSQKGGELELR
                     VRAKGRPVALTVVLYPNDDAWECDCPSQVDPCEHVVAAAISIQQAEKQDTPMETAATRW
                     ARVVYHFTRMDGGLELRRSIVQVDSTETPLEGSLTSLMARPAEAAKLQVENADLLADRI
                     LEQRRTRGTLAPETLEAVLKVLESARNVLLDGRPVAVSDEQVLPRAVVEDRSGQIVVTV
                     TKDPRIQEVVSPGVALASDTLVRLGETSMSGPWLQNLPIVRTYSADHLGDLTSKIMPEL
                     GRRLPVEVRSKRLPRLDRELKPRILLELNQLDAGLSVLPTLVYGAPPVVRIDNGRMVYL
                     RGAVPLRDESAEQRLIHQLRDELNLVPGRRLTVQGSEMVRWADKLRRWRGDLAGDAAGL
                     VSPDVKLRPSLHLESSVTGQGVPDVRFQLSFQVEGAKGEVKAVDAAAVIRAWTEGLGLV
                     PLDGGGWAPLPRAWLDKHGQRVADLLNARQEDGKVSNHALPELTALCETLEQPPPPGLD
                     RLAPLISGFEKLPPPELPAELNATLRQYQLQGVSWLGFLRGAGLGGILADDMGLGKTLQ
                     TICALGPGSLVVCPTSVLPNWAAELKRFRPSLKVCVYHGPGRALEPSADVTLTTYAIMR
                     LDAAVLGAKTWDSLVLDEAQAIKNPDSQVARAAFGLKANFRLALSGTPLENRLEELWSL
                     MHFTNPGLLGGRKHFEDKIARPISEGRQDAAEGLRRRIRPFVLRRLKRDVAPELPPRIE
                     SVMHVQMDERERSVYDAVMAATRKEVVALLNEGGSVLKALEALLRLRQAACHTALVPGQ
                     RANTSSKVETLVDALETAVSEGHKALVFSQWTSLLDLIEPRLKAAGIGFGRLDGTTANR
                     GEVTERFQSTEGEPVLLMSLKAGGTGLNLTAADHVFLVDPWWNPAAEAQAADRAHRIGQ
                     ERTVMVYRLVSQGTVEERILGLQEKKRAIFEAALSEAAAATAITREDLLELFS"
     gene            18092..19912
                     /locus_tag="OZ403_RS14550"
                     /old_locus_tag="OZ403_14550"
     CDS             18092..19912
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011552921.1"
                     /locus_tag="OZ403_RS14550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OZ403_14550"
                     /product="DUF885 domain-containing protein"
                     /protein_id="WP_268784440.1"
                     /transl_table=11
                     /translation="MTRAVLLFAVGFLTMLPESADARPQAAATLHALIQQEWQYQLEHS
                     PTYASVQGDRRWNDRWDDLSLKSIEADHQHNLQVLAKLKKVDRKALSAADQLNYDLFRR
                     DYETWVEEHRFKTYLMPVNHMGGIPEGIKQPPGVQTAYQLADNLRFETVKDYEDWVARL
                     QGFGTYVDQVLALLREGLREKRIHPQVVLQRIPPQVAKQLVADPADSGFFAPFRRFPKG
                     IASAEQQRLSAAGRAAIAQGVLPALKRFHQFLTEEYVPKGTEVVGIWQLPDGAELYDFL
                     ARKFTTTGLGAEEIHALGLAEVQRLRAEMEAVKVQTGFKGTLAEFFRFLRTDARFYARD
                     GDELLMRYRALSKRIDPLLVRLFKTLPRQPYGVEPTPEAMAPDATTGFYYPGASDGSRP
                     GTYLVNLYRPETRPLWEMVPLTLHEAVPGHHLQTALAAEQPGLPEFRRYGYYVAYGEGW
                     ALYCETLGDELGLYSSPYDKFGQLAYDMWRAVRLVVDTGMHVKKWTRQQALDFFMENSP
                     RQELDTTNEIDRYIAWPGQALAYKVGQLKIRELRTRAEQALGPSFDVREFHDVVLLDGA
                     LPLDILEARVQAWVAARQHEAAAPKPPRAP"
     gene            complement(19926..21203)
                     /locus_tag="OZ403_RS14555"
                     /old_locus_tag="OZ403_14555"
     CDS             complement(19926..21203)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013939444.1"
                     /locus_tag="OZ403_RS14555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OZ403_14555"
                     /product="P1 family peptidase"
                     /protein_id="WP_268784441.1"
                     /transl_table=11
                     /translation="MTPRHEPVRLPLRLGIVSCLLLWSLPAEAQSTQARPRARDLGITF
                     GGQSGPNNAITDVSGVEVGHTTLISGDTRGPRGKGAVRTGVTAVLPRGKDGVSEDVFAA
                     IYALNGNGEMTGSHWLTESGQLAGPVMLTNTNDVGTVRDSVISWAMKRGLEWELGLPVV
                     AETWDGLLNDIYGFHVKATHAHRALDGAKGGPVAEGSVGGGTGMVCHSFKAGIGTASRK
                     LPASEGGYTVGVLLQCNYGARHLFTVEGVPVGEELNDLRPCYTGPKKPSHSMFEKMPAC
                     ATSRGDTQPRTPEGAGSIIVVVATDAPLLPHQLERLAKRVPLGIGKMGGLGGNSSGDIF
                     LAFSTQRLKPPTGTDVASVSSLDNERMTPLFEATIQATQEAILNSMLASDTMTGAESSR
                     VYGLPQERLIQVMKKYGRLAPPAPAP"
     gene            21314..22981
                     /locus_tag="OZ403_RS14560"
                     /old_locus_tag="OZ403_14560"
     CDS             21314..22981
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020478808.1"
                     /locus_tag="OZ403_RS14560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OZ403_14560"
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="WP_268784442.1"
                     /transl_table=11
                     /translation="MAEHEDLDALWRKARPDDLASLRRLDAALVRSGYQVEGKTVREWI
                     AALAGDRIRWFDGRDAHDRVCQAGLAAVPALIEALARADQEASWQATRNMLGQCVAALG
                     TIDPLPTCAIPALLDVLRQPVARVRRMVLAVLTRMRPRATPMALRAVLSCLKERGDTPT
                     RLHAAQVLAAMQDPLPEKVRVVALSLLGDAHRAVRREGLHVLARFPRDEEVLTALEEQA
                     ILDDENRNEALRVLSLLAPARAIPRLLEVASSARSRRQEDGPPPPSWRGPLGETRRLED
                     GKRALLFIARLGVRGAEALASLDALRAVEVLAPYVDAIMDDITRAVLRNRAPPLRTERF
                     QEPLCAALLTDVAWPVERTEEPSLALRPWLESLAAFGTEVEVRVALAAARHVLWLWESQ
                     DPNNDWSRRAVMAMDRWLCEPSEAHAAQVAAVGNFTPSQFCAPDAFSAAWSVNYACGCV
                     PRPSAPDAPRRPEEDPLGACVHAACRALSRRSVITFALGASEESPEPLSPRESARQVHR
                     AIVDEVLPWACGAWDPVKDTPRLRDALRADGWRIPGAP"
     misc_feature    complement(21319..21333)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.93"
                     /tool="antismash"
ORIGIN
        1 ttggcgttga cggcttcgta cttcgcctgt tcgagctggg cgtcggccac gtccagctcc
       61 cgctggcgca tgacctccag cgacttcaac gtcgtcaccg cgtcgtcgcg ccaggccgtc
      121 tccgcctcgg ccagggtgag ggcgtgctgg gccgtgcagg cggcgttctg ggcccgctcg
      181 agggccgcga cgtcacccgt tgcctgcgcg gcctcgagcg ctgcctcact tgcttcgtgg
      241 cgggacttcg cggcgtcctc gttgcgttgg gcgacttctc gctccgtctc ggcgtcctgt
      301 ctggccacct gggtgcgggt gatctgctcc cgggcatggt cctccgtgag ctgcgcctcg
      361 cgcacgtttc ccagctcgcc gggtgggacg cgcgccaccc attgcttgtc caccttcgcg
      421 ctggagcgat gggaggcaca gcctcccaac agcatcacgg ccgtgccggc catccccagg
      481 tacatgcgac gcctgcctgg ctgcgccatg ccttcctccc ggtcataggg tcctgtccga
      541 aactgtgcgc atccgggggg agggtgaaag cagcggcgca ccgctcggcg cgtcacacgc
      601 ccctgcccac ggggcagggt ccgcgcgagc acgccgaacg ccgcgctagc gagggtcgag
      661 cagggcctcg aagagcgtgc gtgggtccag cccgggtggc agtccggaga cgccgccgtc
      721 gttcacctcg accaccgccc agcccccgtc ctggagcatg gccacgtcca gggtgaggaa
      781 gggcgagtcg atgcgccggg ccaggggctc gaagccggtg aagtccggca cgtcgacgtc
      841 gagctcgtgg tacggctcgg cggcgaggag ccggccgctt ccgaagaaga gccggaactc
      901 gaggtgggcc gggcccgcgg gtgtccgtcc gtacgtcttg aaggggagga acttccggac
      961 gacgaggccc cgctcgaagc ggtctccgcg ctcatcgacg aggttggcgc aaatctgttc
     1021 gaagcgcgcc tgcgtcgtgc cctcggggat gaagcaggct tcatcccaac gctccttggc
     1081 cgacttcacg tggtccttca ccagccaggg ttgcgagccg agcgcctggg ccgcgtgcca
     1141 ggcttccgcc gcgtccatgc cctccgtcca gacgctgcgc gccgtgtagc gggagagctg
     1201 ggggtaccag ttgggcaggt agagcgccgc cgcgtactgc tcgggcgtgg tcgtcagccg
     1261 gtgccccagg gcggacacgg cttcgtccag cgccatgtac tcctcctccg tcaacatcca
     1321 gccgcggtag aggagccgga gcctgccgcg ctccgggagg gtggacagcg cctgctcggc
     1381 attgccggag agcagggcgc ccaggtctgc ctggtaggtg tcgaccccca gcgcttcggc
     1441 cgcgtcggcc tccacgtcga aggggtcgtc ctgggtggga ttccggccga agaggatggc
     1501 gcgcgcgtga gacggacgtc gggagcctgg catccagaag cctcgcatca agggtggcgg
     1561 tgtgtggggg gcacctccga cgcgtgcgcg cgcgaaccct gacacggcca gatgacgccc
     1621 tggccggagc gctctgtccc ggtccccgcg cggatttcgc ggggaccgga agcgggacgc
     1681 tcagtccccc agcgcgtcgt accggaccag ccggaagcgg gcgccctgcg cctcgcggat
     1741 gcgcgccgcc agcttctcgt gcagctccgg cgtccaggcg ctccaccgct ggaagaaggc
     1801 cgcggtggcc gccttgtcac cgccgtgctg gagcgcgagc accttctcca gcagcgacgt
     1861 cacgacggct gggtacttgt cgtactggat gctcaggcgc gccgtctgcg ggtccgcctg
     1921 gaggaggccg tgctccagga accagttgaa ctgcaccaac tgcatgcgct ggtagggctg
     1981 gtcctcgcgc gggcgcacat tctggagcgt gcggcggatg ccggaggcct gcaccgcgcg
     2041 cagcccggcg gcgtcgagcg tgcccttctt gtggaagtca tgcagcgaga agaggctcac
     2101 caggtccgcc ttcatctcct ccacggcgcc cgcgtagtcc tccagcgcgt cgtccagcgt
     2161 gcgccccttc tggtctcggt ccggccccag gtagtggccc acttcgtgcc acagggtgcg
     2221 ctggaagttg ccttcggaga ccagctcccg gacgtgggcg tccgccaccg cggcgcgcca
     2281 gatgcgctcg tcggacgcga acaggtccgg gttccgcatg atgttctccc gcaggaggat
     2341 ggtgcggccg tagcgacgcg cggcgagcgc gtcgttgggg aggatgctcg cggtgttggt
     2401 gccgcgcgac tggccgaagt cggcgatgac gtcgtagacg cccacgggga tgtcctcgcg
     2461 cacgcgcttc ttcgcggcgt agggcagcgc gtcctccacc gcttggagcc cgcccaggcg
     2521 cttgcgcagc tcctgcgtgg ccgactcatt gctcagcagc accgacaggc tgtggaacgc
     2581 cttcacaccg aagagcgcgt cgtcatacgt ctcatacgcg cccaactgta cgttgagctt
     2641 ctggaagcgg cccgtcaccc aggccgcgtc gccgctctcg tagtcgttgg tgagcaagtc
     2701 ccgcgcgcgg ttgcgcaggt agcgcgccag ctccacgtcg ctggcctcca gccgctgcgc
     2761 cgcgcgcatc accagcccgt aggccttcac caactccggc ccataggcca cggcataggg
     2821 caccgcgtag agcgccttgg cgtcgggccg cttcgccttc gcttgcaggg cctggcgaag
     2881 gcccggatgc agcgtgtcca gcaccgggtg cgtctggagg accttcacgt cctggcgcag
     2941 gttggccgcc gtggcgcggc ggaccaccgt cttctcgctc agaagggact ggcgctcgcc
     3001 ggggttcgcg gccaggaatg cgtccacctc cgcccgcgtg acgtccaccg ggtacacgtt
     3061 gcgcgcggcc acctgcgcgt ccactgggag gaacgcctct cgcgcgttgc tcagggtgct
     3121 ggcgatgggg ccctggtaca ggcggtacag cgcgagcagg tcctgcgtgc gcttggggcc
     3181 gcccagcttc ttgtccaacg cttccaactt cgcgagtgcc gggagcgcct ggtggtggcg
     3241 cgaggactcg tagaggccct ggaagatggc gcccacctcc agcaggtcct tcaccgctgc
     3301 ctgctcgtcg ggcgtgaggc gggagaggtc cggcgacagg cggacctcct gcgtcttggc
     3361 gaggacttcg gccactttct cctctggcca gtagcccgga ggcagggcgg gggagggacg
     3421 gctgggggcg gcggcctgtg ccgacagcgc caggagggcg gcggcgccca gggacagcgc
     3481 gtgggggatt cgcatggcgc gcaagactgc cacggaggtg ggcgtattcc ccacggcttc
     3541 ggttggattg cgtcacgcac gagtgacgtc ctgtgcgccg ggcaagtctt gcgctacatg
     3601 gtgcgcatga aactcaaact tcacttgttt ctttcgctat ccacgtttct cccggcgctg
     3661 atcagctgtg gtgccccgac gtccatggac gccgagcacg aggccgttga gctcgggacg
     3721 cagacgcagg cgctggccac ggggacgccc gctggcgagg gcgtgctgtc cttcctcaac
     3781 gaatactcca tctccctctc cgtgctcgac caggaggtgc cgctgaacgc cctggcggcg
     3841 caggcgctga ttgacttccg cgaggggccg gacggcgtgc tccgcacggg tgatgaccgc
     3901 cgcttcgtga gcatcgagca ggtggacgcg gtgccatacg tgggccccgc ggcgctcgcg
     3961 gcgctggagg cgtacgccaa gggcacgggc cgcgtggagc tgccggtcga tgggcacgtg
     4021 gggaccttcc acggcgtggc cttcaacatg gccgaggccc gccgcgccat ccacgcggcg
     4081 aacacggaga gcgcgtcgaa tctgcagacg ctcttcggca tccccgcggc ggcggtgcag
     4141 agcctggtcg cggcgcgtcc catcctccac atggtgcagt tgtcgcggct gacgaacgtg
     4201 aatgccgtca cgatgggaca gctcaaggct cacacgcagc aggcggccga aggtgacccg
     4261 tgcacgggcc ctggcatctg tcagcccggg ctcatctgcg agggccggcc cggtgacggc
     4321 tccagcccct acggccgctg tgtcgacgct tcgtacctct ccggcaacgg ggacgtgtgc
     4381 tcccgcttcg tggcgtgccc gtcggagaag ctcatctgca tcggcctggc gtcgggctgg
     4441 gtggagggct actgcgcccc ggcgtggatg ggcgcatcct tcatcgagta ctcggacctg
     4501 cggctccagt cgacgaaccc gctggtgacg gcgccgctca ccgtggtggg gctggccacc
     4561 gtgcccatgg acatcaacgt ggaactggac gtcgtccaca ccgcgccgca ccggctggtg
     4621 ctgacgctgg aggacccggg tggtgagacg gccctgctgt gggatggccc gaacgagggc
     4681 acgccgccct cgcgcatcgt cgtgacgcgg ggcatcccgc gcgacggcgt catcaacgga
     4741 cgttggaagc tgcacgtcgc caacccgtcc ggcgtgggca gcggcacgct gcgctcgtgg
     4801 acgctgaagc tcaccagccg ctacgactga gccagtgtat tcgcggtggg cccccgcggt
     4861 tcttcagggg cccaccgcgc gtttcacggt ggctacgcgg gccgggtgac gtgcactgga
     4921 ggccgccgct gggcccaggg ccgcgcctgc tcgagctgtc ccgccagttg gaatagcgtg
     4981 gcctcgtcgg cataccggcc ggcgaactgg acgccgatgg gcaggccctc cgcgctccag
     5041 tgcagcggca cggacatggc gggctgcccg gtgacgttga acagcgcggt gaaggggcag
     5101 tggccgaacg cgtggtcgta ccactcgcgg gccgttcggg gcgcgttggc gtccagcagg
     5161 cccagtggga agggcggcgc cgccaccgtg ggcgacagca gcacgtcgta cttctcgaag
     5221 aagagcccca ccttcctcga cacgaagttg aatacgccga gcgcccgttg aaggtccgtg
     5281 gccgtcaacg cctggccgtg gcgtactacc gcccacgtgg tggcttcgag cgagtccggt
     5341 tcggcctcgc gcccggaata gtggctggcc atcgccacga gggacgcaat ggtcgcggac
     5401 cagacggtgg tgacggcctc gtgcagcagg aggccgtcat gggcgggcgc gtcttcggtg
     5461 acgtcgtggc ccagttcctc gcacaggcgc gccgccagtc gcgcggcttc gatgcactga
     5521 gggctcaccg ggccccccat gggcgaagcc gtcatcagcg cgatgcgcag ccggccaggc
     5581 gtgcggccca cttcctccag gtacgggcgc cgtgggggcg gcgcgaagta ggggtccccg
     5641 gcctctggcc cttgggtggc gtccagtacc gccgcgctat cgcgcacggt gcgcgacagc
     5701 acgtgctcga tgcccatgcc gcagatgaag tcgccggagt tcggtcccag cgagttgcgg
     5761 ccccgtgtgg gcttcagccc gaagacgccg cagagggaag cggggatgcg cagggagccg
     5821 ccgccgtcgt tgccatgcgc caccggcacg atgcctgccg ctaccgccgc cgccgagcca
     5881 ccgctggagc cgcccgggct gcgtcccacg tcccacgggt tgcgagtggg gccgtggagg
     5941 aggggctccg tggtggcgtt gtttccgaac tcgggggcat tcgtccggcc cagcaggacc
     6001 agtcccgcgc gccggtagcg cgccatcaat gcactgtcgt aggggaacac cgttccctgg
     6061 gtcagccggc tcccgaggtc ggtggggacg cccgccgcat gcacgccgat gtccttgatg
     6121 aggaagggca cgccccggaa ggggccgtcg gggaggcctt gcttcagcgc ttcgtgtgcc
     6181 tgggtgtcgc gcgtgtcgat gacggcgttg atcgccgggt tgactcggtg gatggcctcc
     6241 accgccaccc ggagcagctc ctcgggcgtg acttccttcc gacgtaccag ctccgccaat
     6301 cccactgcgt caaagcggct gtagtcatcc aggttcatga atccctcaca ggcgccggtg
     6361 gacatgcggc ggaccgggca cgggaagcag gatacccatg agtcccgggt agtgctccag
     6421 gcgcctcagc ccaccgcctg ggtgcgctcc tcccgttgcg cattcaccag ggacgcgtag
     6481 gcgccctggc gttccagcag ctcctggtgc cgacccacct ccaccacccg gcctgcctcc
     6541 atgacgagga tggtatcggc gttgcgcacc gtgctgagcc ggtgggcgat gacgacgcgc
     6601 gtgcacttca aggacgccag cgcctgctgc acgtgcgcct cggtggtggc gtccagggcg
     6661 ctggtggctt catccaacaa gaggatggcg ggcctgcgca ccagggcgcg ggccagggcc
     6721 agtcgctgcc gctggccgcc ggacatggag aggccccggt ccgtcagcgg cgtgtcgtac
     6781 tgcatgggca tggccatgat gtcgtcgtgg atgtgggcca gcttcgcggc ctccacgaca
     6841 cggtccatgt ccaggtccgg gtcgctcagg gtgatgttct ccctcagcga cgcgttgaag
     6901 aacgaggcat cctgcaacac cacgcccaac tggttgcgca ccgcgcgcag gtccagctcg
     6961 cccagctccg cgccgtcgta ccggacgtgt ccggaggtgg gcaggtagag ccccagcagc
     7021 aggtgcgcca gggtgctctt gcccgcgccc gagcggccga cgagcgccac catctgcccc
     7081 ggctccacgc tgaccgacac gccctgcacc acccaggcgg agtgggggtt gtagcggaag
     7141 cgcacgtcct caaggttaac ggcgccgcgc aacgtgggcg cgcgcccctg gtgcgccgcg
     7201 tcgcgctcgg ggggcgtgtc cagcacgtcg ttgatgcgct ccaggtaggt gctcaggaac
     7261 tggagctgcc cgccggtgcc cagcaggttg gacaggggca ccagcagcgc ggtggccagc
     7321 gcgttgatgc tcagcatctg tcccagggac accgcgccgt ccagcacgcg ccacgcgccc
     7381 acgcacagca ataccagcgg ggacacgcgg cgcagcgtgc ccgtcagcgc gtccagccac
     7441 gcggagaggc ggcctcgctc cagctccacg ttgagcaggt ccacgtagag gttggagtag
     7501 ctgcccacca tgcggccctc cacgccgaag gccttgagcg tctgcatgcc ggacagcatg
     7561 gccatcaggt agctctggct gcgcacgccc atgtccaggc tgcgcgacag ctggctgcgt
     7621 tgtttggccc ggggcagtgc gaacaccagc acctgcaaca ggcccagtcc caccaccagc
     7681 agcccgagcg acgcatccgc caccagcagc aggcccaggt ataggagcac cagcgccccg
     7741 tcgagcgcgc tggacagcag gccggtggag agcagatcgc ggatggcctg ctgcgagccc
     7801 agccgcgtga gcaggtcgcc cgcgggccgg agctggaaga acgggtaggc caggctcacc
     7861 aggtggtcca gcagcccttg cgtcatctgc gagtccagcc gggtgcgcag ctccaccagg
     7921 agctgtccgc gcaccaccga cgagagcagc tcgaagagca acacgcccgc gagcgccgcg
     7981 gacaacacgc ccatcaggga gtagtcctgc cggggcacca cgcggtccac caccatgccg
     8041 gtgagcatcg gcaccgccag cgtcagcacc tggagcacgg cggacagcgc gagcaccttt
     8101 gccagtgtgc cggcctgtcg cttcaccagc ggcaccaggt agcggtacgg cccgcgccgc
     8161 gattggcccg gctggaagtc ctcggacggc tccatcagca gggccacgcc ggtgaagcac
     8221 tggctgaact gctccatgga cacgcggcgg cggccctggt cggggtccac cacctcgacc
     8281 cagccgcggc ccaggcgttc gaagacgacg tagtgcgtga agcgccagtg gaggatggtg
     8341 gccggaggca ggaagggcag ccggtccagg tccacggaga tggcgcgcac gcgcaggccc
     8401 agcttctggg ccgcggcctt cagcgacttc gcgctggcgc cgtcgcgtcc ggggcccgtc
     8461 agctcgcgca ccgcctccag gctcatttcg cggccgtggt aggccagcac catggccaga
     8521 caggcggcgc cgcagtccgt catcgtcatc tgccgcactt cgggcacgcg cttgcgcagg
     8581 ccgagtcgcc accggcgctg gggctgctgc ggagcctcgg ccgtcatggc gacacgtttc
     8641 cttccggggc aatgagcgcc ggccacgcca ggacaccgag cgccagcgcg aggccaaaga
     8701 cgaacaggag cgcgaacgtc caccgcgtcc accggccacc gatgcgcagc aggtcaccct
     8761 cgtcctgcac gacgcgctgg tagtgcgcca gggcttcctt gcggaagatg gagggtcggc
     8821 cgtcggtggg tggctgcatc gcaggggacg ttagcgcatg ggggagggga ctggcctggg
     8881 actgagccag tccccccagg ctcggttcag gaccgagccc taacgcattg tcattagagg
     8941 cagtgatacg gcgggcacgg cgtgcagtag tagctgccga actgctcgca ggtgtccgcg
     9001 cccgagatgt tctccaggac ctcgtcgctc aactccagct cggcggcggg gttggcgggc
     9061 agggacgcgc gctcctccga cgacaggctg ttgaagtact cggggtcacg ccacgcacgg
     9121 aggatgtgtt ccttcttctg gctcatgact tctcctgggc aggaaagggg tttgaatcag
     9181 agacagtggt acggcgggca cggcgtgcag atggcgctgg actgaccggg cttgcagcca
     9241 cagccgccgg tgatgctctc caggacgtcg tcgcccaggt ccagctcggc ggcgggattc
     9301 gcggggagcg cggcgcgctc ctcggcggtc aggctgttga agtactcggg gtcacgccac
     9361 gcacggagga tgtggtcctt cttctggctc atgactgctc ctggaaaggg ctggggaaac
     9421 aacctccgcg gtggccagcc caccaccgtg gaagaggggg atgattcgaa gacggcctcg
     9481 aatcagaagc agtgccgcgg cgggcacggc gtgcactggg ggctggactg gccgggcagg
     9541 cagaagtcgc cgccggtgat gacctccagg aggtcgtccc ccagctccaa ctcggcggcg
     9601 gggttggcgg gcagggatgc gcgctcctcc gacgacaggc tgttgaagta ctcggggtca
     9661 cgccacgcgc ggaggatgtg gtccttcttc tggctcatga ctgctcctgg aaagggctgg
     9721 ggaaacaacc tccgcggtgg ccagcccacc accgtggaag agggggatga ttcgaagacg
     9781 gcctcgaatc agaagcagtg ccgcggcggg cacggcgtgc actgggggct ggactggccg
     9841 ggcaggcaga agtcgccgcc ggtgatgacc tccaggaggt cgtcccccag ctccaactcg
     9901 gcggcggggt tggcgggcag ggatgcgcgc tcctccgacg acaggctgtt gaagtactcg
     9961 gggtcacgcc acgcgcggag gatgtggtcc ttcttctggc tcatgactgc tcctggtcac
    10021 ggctggaggg acggccatcc ggggtgccca gcccttcacc tcggacgatt cgtggaggcg
    10081 cgaccgtcag cagcgagggc aaccgctccg gcatggccag ccgcgccagt ccgtaggcga
    10141 tgcccgccag gcccaccatc atgcccggcg tctccgtgct gccttgcagg ccgaagaggt
    10201 agccgtgctc ggagatgccg cgcaggatgc cgcccgccac cgcgttcgtg cgctcctgga
    10261 gctttgagtc ccccagcgtg gccgccgctt ccaacaggaa gtccgcgttg cccaggtcgc
    10321 cgtgacacag accgtggttg cgtccgaagc cccgagccag cgtggagtcc agcgcgatgg
    10381 caatctcctc gcgcaccgcg gcgtcgtcca cgaaggggag cccggacagt cgtgccaggc
    10441 cgatgccggg ggcgccggta caccaggccc agaggaagtg ctccgcgcct tccgccgccg
    10501 ccagttcctt cgcgcccacg cgcaggtcgg gccagttgcg ctcctcgggc gtgtagagcc
    10561 cgcgctcgaa ctccatgccc gccaccgcgg cgtcacgcag gcgcgtatcg cccgtccgcg
    10621 cgaacagccg cagcagcgcc aggctgatgc cggcggctcc gtgcgccatg cctgcgaggt
    10681 aacggtttcc ggcggcttcg caaatccagg ccgcgcctcg ggcctggggc gtggacgtct
    10741 ccagcagccg ctggccgcag gcgtccaccg tggcccacaa cgtgtccgac gggcggtgct
    10801 caccgagcac cagcagcgcc agcaggcagc ccgcggcgcc cgcgcccacg tccaacaccg
    10861 tgtccttctc caccaggggc cgcagccgcc gtacgtatcc ggcggcttcg tccaaaaggg
    10921 cgtcgtcctt ccaaagcacg cccaggtgcg tcagcgcgta gaggatgccg ccccagccgt
    10981 tgaggatgcc caaccccacc acgccggcgg gctcctccgc gaggaggcgc gcctgggtgc
    11041 gcagcgtggc ccgcgccagc cgcgtgaagc gcgcgtcttg cgtgacgtcc cccaggtagc
    11101 ccagcgcgag cgcgatgcca gcacggccct ggaacacgtc cggccctggc gaaccgagcc
    11161 tccatccgcc gtctcccgca tccaggccga gccagtgcgc ttcgtcacgg cgctcgaagg
    11221 ccaagggcag cagccgttcg cccgcgcgtc gtgcttccgc gagcaacgcg tcgcggaggc
    11281 ccggctgggt gtgctccctg aagggatacg tcggacgcgc caccgtctgc gagctcagca
    11341 gcaggacatc cagcgagcgc tccagtaccc agcgctgccg cgtctggtcc tccggcgaca
    11401 ggcccttcag ccggcggcgc acgcgcgcca tgcccgtctc ctggaagaag tccggcaggc
    11461 gctggcccga gcccgcctcc aggtccttcg agtcggcgcg cgcggtgaag tacggcaggt
    11521 ctccccgctc caactgctcc gtctccaggg gcacgagcgc cgcgaagtcc gggacaggca
    11581 ccacggcgcg ccacaggtgg tcgaagaagc gttggcgctc gagcccatcc gtcagcacgt
    11641 gcgggtggta gctctcgaag aggagcgcgc catacaccgc cgtgttgcgg aagaggatgc
    11701 gcatgggcac gggcgcgaag gcggccagcg gcccgtcctc ggcgagcagc gcctcgcggt
    11761 gctccagcag caggctgtac atgcgggtga agccgtcggc cagcgcgtcg cggtaggcca
    11821 ggacgggcgc ggtctcgccc tccaggcgcg gcaggttgtt ggacccgggt agctccaccg
    11881 gacgccgctc gaagcgcatc cggtccgttc ctcgctccgc cgtcatcaag taggcctgcg
    11941 gcgtgagctg acctgcacga gcgcccagtc cgctcaggtc caccccggcc ttcttgcgcg
    12001 tgccccagaa ctgctgcggc agcagtccgc tgcgtagcac cgacaccggc ggcgcctcta
    12061 ccgcgtgctc ggagtctcga agcgtgcgcg tgcctgacag cgggtggaag agcgtctcca
    12121 cgtccaccag caccgggtgc tcaccggcgg cgatgaggtt ctcgaagtgc aggtccgtgc
    12181 cgtccagcgc gtgcatcagc gcgacgtagg caccctggcg ttcgtagaag cgccggacct
    12241 cctccgtcga cgcgcacggc gcgggggcca cgtactccat ccacccgtac tcgccccggt
    12301 ccagcgcctc cgcgcccttc atgacgggcg tggcgccgcg cgcgttgagc cacgtgagga
    12361 gttgctggag cccggcctct gctcccagcg agcgcggctt gtagacgatc cgcagcccgg
    12421 actcgaagcg gaggatgaag acgccctgac cgccccggtg cggatcggag aagccgccac
    12481 gtgcctccac cagcgcgccg ggagactggc ccgcgttgaa ccgctgccag agcaggggcg
    12541 cgtcgcgtgt cagccgcttc atcagtccca ggcagttgga ctcccactcc gcgatgcgca
    12601 ggacgacgca gcgggccagc acggggtagc gctccaggat gtccagggcg aaccgcggct
    12661 ggcgcagccg cttcgtgaag tcctggaagc gcgcctccgg tgtgtctccc gcgagcagtc
    12721 cctccaactg ggcggcatgg agctccacca ccatggcgcg gcccaacgct ggtgccagca
    12781 cttggggcag gtggcccagc atcgtggaga cgacgacgct cggctccagg tcgagcccag
    12841 gcgcggcgtg cttcaggggc ttcagcgcgg cggtgagctg cgtcacggcg cgcgacacca
    12901 gcggctccac caggggcagg aaggccgagc ggtccgggcc ctccgtgcgc tcgggccaga
    12961 tgacgggcgc gtgcgagggc tccgcgtagg ctcgctccag cacctgcacc cagccgggga
    13021 cttcagcagg cgtggtccag ggtgcctcgg cgggcacctc cagcagcatg agcagctccg
    13081 tctctgtcag cccagaggat tgcaatctgc gctgccacca gtccgcctgt ccgaagggct
    13141 cctgctgacg ccacgcatcc aatcgcttgc gcgccgcggc ggatgcatcg ggttgcgtcg
    13201 tactggtttt gagagtgaat acggctcgct cggcgagtgt ggtggcccgt gcccagcgtg
    13261 cgaaccgcga cggagcgttg gctcccggcg tcgcctcgtc ctgcctctgc gtgatttcca
    13321 cgcgtcctct cgtttcctgg gcaaagcccg gtgagctggc ttcgttggag tatcagggag
    13381 acgactgtga tacaggtaag gcatttcgtc tttgcatgtc aatgctgagc gcccgtgtcc
    13441 gcatggcatg caatacatgc gggaaggtgg gagtgatttg tacgacgcac tcatcatcgg
    13501 cagtggcgcg ggcggcgggc cgctggcgtt gaagttttcc caggcagggc ttcgcgtgct
    13561 ggtgttggag cgaggcccgc ggcactcgcc gcgggaatac gcgcacgatg cgacggggtt
    13621 ggggccgcag gacctcatcc cccgcgtcga agacgaccca cataccgtgg tgacacggaa
    13681 gacgtccgtg ccgctgcgca ccgcgctggg ctggacggcc agctgcgtgg gcggcggcac
    13741 cgtgcacatg ggtggatatt tctatcgctt ccatccggat gacctgcgca tgcgcagccg
    13801 tttcggtgac tacgaggagc tggcggactg gccttatgac tacgccgcgc tggagccctg
    13861 gtatgccgtg gcggagcaag aggtgggcgt ctccgggctc gcgggtgtga atcctttcga
    13921 gggacctcgc tcgacaccgt ttccgctgcc tccgctggat gcgcatcccc tggccgccgc
    13981 gttggaggag gcctgcgcgc ggcgggggct gcatgccttt tcaacgccgc gctccatcaa
    14041 ctcgcggccc tatcaggggc gccccgcgtg cgcttactgc ctggagtgtt ccggcctggg
    14101 atgtccggtg ggcgcgcgag gaagctcgca ggccgcgctg ctgcctcgcg ccgaggccac
    14161 gggccactgt gaggtccgcg cgcggtgtca tgtccgcgaa gtcacggtgg ggccggatgg
    14221 ccgcgccacc gggtgcgtgt acctggacgc ggaggggcag gagcaccgcg tgacggcccg
    14281 cgtggtgtgc gtgtgctgtt cgtccgtgga gtccgcgcgg ctcttgttgc tgtcgcgctc
    14341 gccgcgcttt cccaacgggt tggcgaatgg cagcgggcgg gtggggcggc acctccagtt
    14401 ccacgccgtc accatggcgc aggcgcgcct gccgcgcgac cgcctccccg gtgcgctgct
    14461 ggagaatccg cacccgttca tcggccgctc ggtgatggac cactacttcc tgcccgatgg
    14521 cgtgtcggac ctgcccaagg gcggcatcct ccgcttcgga cgcgggccgc ccgtgcccga
    14581 gtcccgggac ggggcgaagg cgtcggacgt gctcttctgc gaggtgttcc acgacttcct
    14641 cccgaacgcc ggaaccttcg tggagctgga cccggaggtg aaggaccggt gggggctgcc
    14701 ggtggcgcgc atccacctgg accggccacg gcaccacgtc cgcgcggggc aatggctgct
    14761 ggcgcgcacc ttcgagttgt tccgcgactt gggcgccgag gagtgtgtcc ccctcatcgt
    14821 gggcggcacc tcgtcgtacc tggtccaggg gacgtgccgc gccggagacg acccggagac
    14881 gtcggtgctg gacggccact gccagacgca cgaggtggac aacctgttcg tggtggacgg
    14941 cagtttcatg cccacctccg gcggggcggc ccccacgttg accatcctgg ccaacagctt
    15001 ccggagcgcg gaccacatcg tccgccgctt ccaggcgggg gacttcgcct gagccggggc
    15061 agggggaggc cgcctgccac gcgacggtac gcgctcatgg ccgttgcgcg acgcatcctc
    15121 ggggcgtagg gaaacaacgc cccatgtccg ccaccgccca actgctcgaa accgtccgga
    15181 aggaagccaa gccgggaatc tggtccaacg gcgtgaacct cgcccgctcc ggagccgtgg
    15241 tgctccagtc ccagaaaggg ggcgagctgg agctgagggt gcgcgccaag gggcgcccgg
    15301 tcgctctcac ggtcgtcctg tacccgaacg acgacgcctg ggagtgtgac tgccccagtc
    15361 aggtggaccc ctgcgagcac gtggtggcgg cggccatctc catccagcag gcggagaagc
    15421 aggacacgcc catggagacg gcggccaccc gctgggcccg cgtcgtctac cacttcaccc
    15481 gcatggacgg cggcctggag cttcgccgct ccattgtcca ggtggacagc acggagacgc
    15541 cgctggaggg cagcctgacg tcgctgatgg cccggcccgc ggaggccgcg aagctccagg
    15601 tggagaacgc ggacctgctg gccgaccgca tcctggagca gcggcgcacg cgcggcaccc
    15661 tggcaccgga gacgctggag gcggtgctca aggtgctgga gtcggcgcgc aacgtgctgc
    15721 tcgacgggcg cccggtggcg gtgtccgacg agcaggtgct gccgcgcgcg gtggtggagg
    15781 accgcagcgg ccagattgtg gtgacggtga ccaaggaccc gcgcatccag gaggtggtca
    15841 gccccggggt ggcgctcgcg agtgacacgc tggtccgcct gggcgagacg tccatgtccg
    15901 gcccgtggct gcagaacctg cccatcgtcc gcacgtactc ggcggaccac ctgggggacc
    15961 tgacctcgaa gatcatgccc gagctggggc gccgcctgcc ggtggaggtc cgcagcaagc
    16021 ggctgccgcg cctggaccgc gagctgaagc cgcgcatcct gctggagctg aaccagctcg
    16081 acgctggctt gtccgtactg cccacgctcg tctacggcgc gccgccggtg gtgcgcatcg
    16141 acaacgggcg catggtgtac ctgcgcggcg cggtgccgct gcgcgacgag tccgccgagc
    16201 agcgcctcat ccaccagctg cgcgacgagc tgaacctggt gcctggccgc cggctgacgg
    16261 tgcagggctc ggagatggtg cgctgggcgg acaagctgcg gcgttggcga ggcgacctcg
    16321 ccggtgacgc ggcgggtctg gtgagtcccg acgtcaagct gcgcccgtcg ctccatctgg
    16381 agtccagcgt cacggggcag ggcgtccccg acgtgcgctt ccagctctcc ttccaggtgg
    16441 agggggccaa gggcgaggtc aaggccgtgg acgccgccgc cgtcatccgg gcttggacgg
    16501 aggggctggg gctggtgccg ctggacggtg gtggctgggc gccgctgccc cgggcctggc
    16561 tggacaagca cggtcagcgc gtggcggacc tgctcaacgc gaggcaggag gatgggaagg
    16621 tctccaacca cgcgttgccg gagctcaccg cgctgtgcga gacgctggag cagcctcctc
    16681 cgccgggcct ggaccggctg gcgccgctca tctccggctt cgagaagctg cccccgcccg
    16741 agctgcccgc ggagctcaac gccacgctgc gccagtacca gctccaaggc gtcagttggc
    16801 tgggcttcct gcgcggcgcg gggctgggcg gcatcctggc ggatgacatg ggtctgggta
    16861 agacgctcca gacgatttgc gccctggggc ccgggtcgct cgtggtgtgc cccaccagcg
    16921 tgctgcccaa ctgggccgcg gagctgaagc gcttccgccc gtcgctcaag gtgtgcgtgt
    16981 accacgggcc cggccgcgcg ctggagccgt ccgccgacgt gacgctcacc acctacgcca
    17041 tcatgcgcct ggacgcggcg gtgctcggcg cgaagacgtg ggactcgctg gtgctggacg
    17101 aggcgcaggc catcaagaat ccggacagcc aggtggcgcg cgcggccttc gggctcaagg
    17161 cgaacttccg gctcgcgctc agcggcacgc cgctggagaa ccggctggag gagctgtgga
    17221 gcctcatgca cttcaccaac ccgggcctgc tcggggggcg caagcacttc gaggacaaga
    17281 ttgcccggcc catctccgag ggccggcagg acgcggccga ggggctgcgg cgccgcatcc
    17341 gtcccttcgt gctccggcgc ctgaagcggg atgtcgcgcc cgagctgccg ccgcgcatcg
    17401 agtccgtcat gcacgtgcag atggatgagc gtgagcgctc cgtctacgac gcggtgatgg
    17461 cggccacgcg caaggaagtg gtggccctgc tgaacgaggg cggcagcgtg ctgaaggcgt
    17521 tggaggccct gctgcggctg cgtcaggccg cgtgtcacac cgcgctcgtt ccgggccagc
    17581 gggccaacac gtcgtccaag gtggagacgc tggtggacgc gctggagacg gccgtctccg
    17641 aaggccacaa ggcgctcgtc ttctcgcagt ggacgtcgct gctggacctc atcgagccgc
    17701 gcctgaaggc ggcgggcatc ggcttcggcc ggctggacgg caccacggcc aaccgcggcg
    17761 aagtcaccga gcgcttccag tccacggaag gtgagccggt gctgctcatg tccctcaagg
    17821 cgggcggcac gggcctcaac ctcacggcgg cggaccacgt cttcctggtg gacccgtggt
    17881 ggaacccggc ggcggaggcg caggccgcgg accgcgccca ccgcattggc caggaacgca
    17941 cggtgatggt gtaccggctg gtgtcccagg gcaccgtgga ggagcgcatc ctggggctcc
    18001 aggagaagaa gcgggccatc ttcgaggcgg ccctgagcga ggccgccgcc gcgacggcca
    18061 tcacccgtga ggatttgctc gaactcttct catgacgcgc gcagtccttc tcttcgcagt
    18121 ggggttcctc acgatgcttc ccgaatccgc cgacgcccgg ccccaggccg ccgccacgct
    18181 gcacgcgctc atccagcagg agtggcagta ccagctggag cacagcccga cgtacgcgtc
    18241 cgtgcagggt gaccggcgct ggaacgaccg ctgggatgac ctgagcctca agtccatcga
    18301 ggcggaccac cagcacaacc tccaggtgct cgcgaagctg aagaaggtgg accgaaaggc
    18361 gctctccgcc gcggaccagc tcaactacga cctgttccgc cgcgactacg agacgtgggt
    18421 ggaggagcac cgcttcaaga cgtatctgat gccggtgaac cacatgggcg gcatcccgga
    18481 gggcatcaaa cagccgccgg gcgtgcagac ggcctaccag ctcgcggaca acctgcgctt
    18541 cgagacggtg aaggactacg aggactgggt ggcccggctc cagggcttcg gcacctacgt
    18601 ggaccaggtg ctggcgctgc tgcgcgaggg actgcgcgag aagcgcatcc atccccaggt
    18661 cgtcctccag cggattccgc cgcaggtggc gaagcagctc gtggcggacc cggcggacag
    18721 cggcttcttc gcgccgttcc gccgcttccc caagggcatt gcctccgcgg agcagcaacg
    18781 cctgtccgcg gcgggccgcg cggcgattgc gcagggcgtg ctccccgcgc tgaagcgctt
    18841 ccaccagttc ctcaccgagg agtacgtccc gaagggcacg gaggtggtgg gcatctggca
    18901 gctccccgac ggcgcggagc tgtatgactt cctcgcgcgc aagttcacca ccacgggtct
    18961 gggcgcggag gagattcacg cgctcggcct ggccgaggtc cagcgcctgc gcgcggagat
    19021 ggaggcggtg aaggtccaga cgggcttcaa gggcacgctg gcggagttct tccgcttcct
    19081 gcggacggat gcgcgcttct atgcgcggga cggggacgag ctgctgatgc gctaccgggc
    19141 cttgtccaag cgcatcgacc cgctgctggt gcggctgttc aagacgctgc cccggcagcc
    19201 ctatggcgtg gagccgacgc cggaggccat ggctccggac gcgaccaccg gcttctatta
    19261 cccaggggcg tcggatggct cgcggccggg cacgtacctg gtgaacctgt accggccgga
    19321 gacgcgtccc ctgtgggaga tggtgccgct cacgctgcac gaagccgtgc ccggtcacca
    19381 ccttcagacg gccctggccg ccgagcaacc cggcctgccc gagttccgcc gctacggcta
    19441 ctacgtggcc tatggcgaag gctgggcgct ctactgcgag acgctgggcg acgagctggg
    19501 cctgtactcc agcccctacg acaagttcgg ccagctggcc tacgacatgt ggcgcgcggt
    19561 gcggctcgtc gtcgacaccg gcatgcacgt gaagaagtgg acgcggcagc aggcgctcga
    19621 cttcttcatg gagaactcac cgcgccagga gctggacacc accaacgaga ttgaccgcta
    19681 catcgcctgg ccggggcagg cgctggcgta caaggtgggg caactcaaga ttcgcgagct
    19741 gcgcacgcgc gcggagcagg ctttgggccc gagcttcgac gtgcgcgagt tccacgacgt
    19801 cgtgctgctc gacggcgccc tgccgttgga catcctggag gcgcgggtgc aggcgtgggt
    19861 ggcggcgcgg cagcatgagg ccgccgcgcc gaagcctccg cgcgcgccct gaggcgcgcg
    19921 cggcgtcacg gcgcgggcgc gggaggcgcc agccggccgt acttcttcat cacctggatg
    19981 agccgttcct ggggcaggcc gtagacgcgg ctgctctccg cgcccgtcat cgtgtcggac
    20041 gccagcatcg agttgaggat ggcctcctgc gtggcctgga tggtggcctc gaagagcggc
    20101 gtcatccgct cgttgtcgag cgacgagacg ctggccacgt ccgtgcccgt ggggggcttc
    20161 agccgctgcg tggagaaggc caggaagatg tcgccagagg agttcccccc caggccgccc
    20221 atcttcccga tgcccagcgg cacgcgcttc gccagacgct ccagttgatg cggcagcagc
    20281 ggcgcgtccg tcgccaccac cacgatgatg gagccggcgc cctcgggcgt gcggggctgg
    20341 gtgtcgccgc gcgacgtcgc gcaggccggc atcttctcga acatgctgtg gctcggcttc
    20401 ttgggcccgg tgtagcaggg gcgcaggtcg ttgagctcct cgcccacggg cacgccttcc
    20461 acggtgaaga ggtggcgcgc gccgtagttg cactgcaaca gcactcccac ggtgtagccg
    20521 ccctccgacg cgggcagctt gcgtgacgcc gtgccgatgc cggccttgaa gctgtggcac
    20581 accatccccg tgccgccgcc caccgagccc tccgcgacag ggccaccctt ggcgccgtcg
    20641 agcgcgcggt gggcgtgcgt ggccttcacg tggaagccat agatgtcatt cagcaggcca
    20701 tcccacgtct cggcgacgac aggcagcccc agctcccact ccaatccgcg cttcatcgcc
    20761 cacgagatga cggagtcgcg gacggtgccc acgtcgttgg tgttggtgag catgacgggg
    20821 ccggcgagct ggccggactc ggtgagccag tgggagcccg tcatctcacc gttgccgttg
    20881 agggcgtaga tggctgcgaa gacgtcctcg gacacgccgt ccttgccgcg aggcaacacg
    20941 gcggtgacgc cggtgcgcac cgcgcccttt ccccgcgggc cgcgggtgtc gcccgaaatc
    21001 aacgtcgtat ggcccacctc cacgccggac acgtcggtga tggcgttgtt cgggcccgac
    21061 tgtccgccaa aggtgatgcc caggtcgcgg gcgcggggcc tcgcctgggt ggactgcgct
    21121 tccgctggaa gggaccacag caacagacag gacacgattc ccagtcgcaa agggagacga
    21181 acgggttcat ggcgtggcgt catatcgcga ccgcgtcagg cccccaactg gaggtcccgt
    21241 ctggccatgt ccgttgtctc cctgccagta tctctctgag tcccctcgcc gtcgggaggc
    21301 cgccgggccg cacatggctg aacacgaaga cctcgatgcg ctgtggcgca aggcgcggcc
    21361 ggatgacctc gcctcgctgc ggcggctgga tgccgcactg gttcgttccg gctaccaggt
    21421 ggaaggaaag acggtgcgcg agtggattgc cgcgctcgcc ggagaccgca tccgctggtt
    21481 cgacggcagg gatgcacatg accgcgtgtg ccaggcgggg ctcgcggcgg tgcccgcgct
    21541 catagaggcc ctggcgcgag cggaccagga ggcttcctgg caagccacgc gcaacatgct
    21601 cgggcagtgc gtcgcggcgc tgggcaccat cgacccgctt cccacctgtg cgattccggc
    21661 gctcctcgac gtgctccgtc agcctgtggc gcgggtccgg cgaatggtgt tggcggtgct
    21721 gacgcgcatg cgcccacgcg ccacccccat ggccctgcgc gccgtcctgt cgtgtctcaa
    21781 ggagcggggc gacacaccga cgcggttgca cgcggcgcag gtgctggcgg cgatgcagga
    21841 cccgttgccg gagaaggtcc gcgtcgtcgc gctatcgctg ctcggagatg cccaccgcgc
    21901 ggtgcgccgg gaggggctcc atgtcctcgc tcgctttccg cgcgacgaag aggtcctcac
    21961 cgcgctggag gagcaggcca ttctggacga tgagaatcgg aacgaggccc tgcgcgtgct
    22021 gtcgctgctg gcgccggccc gagcgattcc aaggctgctc gaagtggcga gcagcgcgag
    22081 gtcgcgccgg caagaagacg ggccgcctcc gccttcctgg cggggcccgc tcggtgagac
    22141 ccgacggctc gaagatggga agcgagccct cttgttcatc gcccggctgg gcgtccgggg
    22201 cgcggaggcg ctggcgtcgc tcgacgcgct ccgggccgtc gaggtcctgg caccctatgt
    22261 ggacgccatc atggacgaca tcacgcgcgc ggtgctgcga aatcgagctc cgcccttgag
    22321 gacggagcgt ttccaggagc cgctctgcgc cgcgctcttg acggacgtgg cgtggcccgt
    22381 cgagcgcacc gaggagccgt ccctggcgct gcgcccgtgg ctcgagtccc tggccgcctt
    22441 cggcacggag gtggaggtgc gcgtggcgct cgccgccgcg aggcatgtgc tgtggctgtg
    22501 ggagtcccag gacccgaaca acgactggtc gcgccgcgcc gtcatggcca tggaccgctg
    22561 gctctgtgag ccctcggagg cgcacgcggc gcaggtggcc gcggtgggaa acttcacccc
    22621 cagccagttc tgcgcgccgg atgccttctc cgccgcctgg tcggtgaact acgcctgcgg
    22681 gtgtgtcccc cggccgtccg cgcccgacgc cccgcgccgg cctgaagagg accccctggg
    22741 cgcgtgcgtc catgccgcgt gccgggcgct gagccgccgg tcagtcatca ccttcgcgct
    22801 gggcgccagc gaggagtctc cagagccact cagcccgcgt gagtcggcac gacaggtcca
    22861 tcgtgccatc gtggacgagg tgctgccctg ggcctgtggt gcctgggacc ccgtgaagga
    22921 cacgccacgg ctgcgcgatg cgctgcgcgc ggacggctgg cgcatccccg gcgcgccctg
    22981 acttcgcgcg tccggctgtc cgcgggtgtg cagtggccgt gagaccgccg ggccaggaag
    23041 tgtgcacgcg tcagacgctg acgtacgtga atgccccccg agcgcgcgtg cggtccgcgg
    23101 gggcaggtga caacccgctg gccacaggcc tgaggtccgg ccccgtgact catgggggcg
    23161 tccatggcgt ggagggcagg gggcggagtc cagcggtggt gggccgccct gctgtggggg
    23221 acgtgtgtcc tgctggcggg cgtcgtccgc gcggacgggt ggcacgtgga atacgacgcg
    23281 ccggtcccgc tcttcctgga ccgcagctac atcctcgact c
//
