LOCUS       NZ_CP113837            22494 bp    DNA     linear   CON 26-JAN-2024
DEFINITION  Kitasatospora sp. YST-16 chromosome, complete genome.
ACCESSION   NZ_CP113837
VERSION     NZ_CP113837.1
KEYWORDS    RefSeq.
SOURCE      Kitasatospora sp. YST-16
  ORGANISM  Kitasatospora sp. YST-16
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Kitasatospora.
REFERENCE   1  (bases 1 to 7659304)
  AUTHORS   Mo,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-NOV-2022) College of Life and Environment Science,
            Hunan University of Arts and Science, No. 3150 Dongting Avenue,
            Changde, Hunan 415000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 8.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 95.0x
            Sequencing Technology             :: Oxford Nanopore PromethION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/24/2024 04:37:03
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,903
            CDSs (total)                      :: 6,801
            Genes (coding)                    :: 6,649
            CDSs (with protein)               :: 6,649
            Genes (RNA)                       :: 102
            rRNAs                             :: 9, 9, 9 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 9, 9 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 152
            CDSs (without protein)            :: 152
            Pseudo Genes (ambiguous residues) :: 0 of 152
            Pseudo Genes (frameshifted)       :: 59 of 152
            Pseudo Genes (incomplete)         :: 103 of 152
            Pseudo Genes (internal stop)      :: 5 of 152
            Pseudo Genes (multiple problems)  :: 14 of 152
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:05:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6550624
            Orig. end                         :: 6573118
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP113837.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Mo Ping.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22494
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="guanidinotides"
                     /region_number="21"
                     /rules="(pgm1 and pgm_amidino)"
                     /tool="antismash"
     cand_cluster    1..22494
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(pgm1 and pgm_amidino)"
                     /kind="single"
                     /product="guanidinotides"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22494
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12494](+)"
                     /cutoff="20000"
                     /detection_rule="(pgm1 and pgm_amidino)"
                     /neighbourhood="10000"
                     /product="guanidinotides"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12494
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(pgm1 and pgm_amidino)"
                     /neighbourhood="10000"
                     /product="guanidinotides"
                     /protocluster_number="1"
     misc_feature    complement(364..380)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 18.76"
                     /tool="antismash"
     misc_feature    433..446
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.09"
                     /tool="antismash"
     misc_feature    477..492
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.07"
                     /tool="antismash"
     misc_feature    complement(512..526)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.01"
                     /tool="antismash"
     gene            complement(581..1687)
                     /locus_tag="OU787_RS29545"
                     /old_locus_tag="OU787_29545"
     CDS             complement(581..1687)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (62-365). E-value: 2e-20.
                     Score: 65.2. Matches aSDomain:
                     nrpspksdomains_OU787_RS29545_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012382.4"
                     /locus_tag="OU787_RS29545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_29545"
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_268661199.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.3e-18, bitscore:
                     65.1, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFGRFSRAGTGSAKWARAGAGRIAMGVADMDLPGPPAVGAALRVR
                     AGHPAFGYPVAEAADRVLVADWYRRRHGVEVDPGWVMLLPFAPGTAVRLLLEAVRPLSG
                     PAVFVTPEWGGFARVCGAAGVAVRELPLLETGDPADPYRLPLAEVAAARPGLVLLSSPH
                     NPSGRIWPAADVRALAAAAAPGLLVSDEVHGDLRHPDAGAAQPVAVAVTGGAANVVTLN
                     SVGKTFNVSGLPSCFALVPDAGLRERLAAVMAGFGLWEGGLLGAVAQRAALAEGGPWLD
                     GLLGHLVRARELAVGALGGAVLARPQSSYLLWLDGAGLGSREELLTERHVELADGADFG
                     AAGSGRLRLNFALPLDRLRTALTRLTCE"
     aSDomain        complement(593..1501)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_OU787_RS29545_Aminotran_1_2.1"
                     /evalue="2.00E-20"
                     /label="OU787_RS29545_Aminotran_1_2.1"
                     /locus_tag="OU787_RS29545"
                     /protein_end="365"
                     /protein_start="62"
                     /score="65.2"
                     /tool="antismash"
                     /translation="LVADWYRRRHGVEVDPGWVMLLPFAPGTAVRLLLEAVRPLSGPAV
                     FVTPEWGGFARVCGAAGVAVRELPLLETGDPADPYRLPLAEVAAARPGLVLLSSPHNPS
                     GRIWPAADVRALAAAAAPGLLVSDEVHGDLRHPDAGAAQPVAVAVTGGAANVVTLNSVG
                     KTFNVSGLPSCFALVPDAGLRERLAAVMAGFGLWEGGLLGAVAQRAALAEGGPWLDGLL
                     GHLVRARELAVGALGGAVLARPQSSYLLWLDGAGLGSREELLTERHVELADGADFGAAG
                     SGRLRLNFALPLDRLRTALTRL"
     misc_feature    complement(1839..1856)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.34"
                     /tool="antismash"
     misc_feature    complement(1845..1858)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.3"
                     /tool="antismash"
     misc_feature    complement(1891..1902)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.52"
                     /tool="antismash"
     gene            1982..2323
                     /locus_tag="OU787_RS29550"
                     /old_locus_tag="OU787_29550"
     CDS             1982..2323
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="OU787_RS29550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="OU787_29550"
                     /product="hypothetical protein"
                     /protein_id="WP_268661200.1"
                     /transl_table=11
                     /translation="MPKNSTAIYLRCYPEDRWEMMSHRHALEGLADRRGLARPILYLDN
                     GTRSTERAPRLEHLLADIAVGWVDTVLIPGTWVFALCPTTARTTADRIRTTGAHLIEMT
                     SPRAILQAA"
     gene            complement(2388..2606)
                     /locus_tag="OU787_RS29555"
                     /old_locus_tag="OU787_29555"
     CDS             complement(2388..2606)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010986698.1"
                     /locus_tag="OU787_RS29555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_29555"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_268661201.1"
                     /transl_table=11
                     /translation="MAHADLKSPADDRRWRKSSYSNSDGGQCIEVDDAHPGHVRDSKDP
                     RGPILTFPPAVWNAFCRAAAAGEFGEV"
     gene            complement(2682..2900)
                     /locus_tag="OU787_RS29560"
                     /old_locus_tag="OU787_29560"
     CDS             complement(2682..2900)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135453.1"
                     /locus_tag="OU787_RS29560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_29560"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_030460658.1"
                     /transl_table=11
                     /translation="MAHDDLKSPTDERRWRKSSYSNSDGGECIEVDDAHPGHVRDSKDP
                     QGPILTFPPAAWNAFCHAAATGEFGEV"
     gene            complement(2890..3723)
                     /locus_tag="OU787_RS29565"
                     /old_locus_tag="OU787_29565"
     CDS             complement(2890..3723)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040183.3"
                     /locus_tag="OU787_RS29565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_29565"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_268661202.1"
                     /transl_table=11
                     /translation="MAWPEREVDPSKSARHFYGAEIRRLRTERGWSLARLAEEVHFSPS
                     TMSRVENGDIRVPDSLSEQLDSVLMTDGFFARMFPLARQESHPAKYQEFLSLADSARVY
                     ESYSPGIHGLLQTEACARRILRSGIPYGPDEEVEQRVQARLERQIRMYNSAECRYWFIL
                     DEAAIRRQIGTPAEMTEQLTAILTAAQLSNVVVQVLPFSAGVHSETSSMSILRLEDNRQ
                     VAYEESTRAGVFFEEERDVAERRALYDLLRAQALSKAESERLIRAAMEGLIPDGS"
     gene            3996..4349
                     /locus_tag="OU787_RS29570"
                     /old_locus_tag="OU787_29570"
     CDS             3996..4349
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018890845.1"
                     /locus_tag="OU787_RS29570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_29570"
                     /product="VOC family protein"
                     /protein_id="WP_198545009.1"
                     /transl_table=11
                     /translation="MALEWEQIMVDSADPITLGRWWAEALGWVVVDETEEIIEIRPEPD
                     RMPGLLFVGVPEGKTTKNRLHPDFRPDDQEAEVSRLISLGARRVDPVQDGQHWVTLLDP
                     EGNEFCVLSAPKG"
     misc_feature    complement(4371..4386)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.27"
                     /tool="antismash"
     misc_feature    4372..4385
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.18"
                     /tool="antismash"
     gene            4436..5464
                     /locus_tag="OU787_RS29575"
                     /old_locus_tag="OU787_29575"
     CDS             4436..5464
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1066: alpha/beta hydrolase domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014152001.1"
                     /locus_tag="OU787_RS29575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_29575"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_268661203.1"
                     /transl_table=11
                     /translation="MTTTHRTTPDFPDCPNFPDFLRGEPLDGHPLRAHLRDLDCLEETL
                     AFNRAFERAAGSRPVRRGPLDAETLARLRRNRLGGDTPPRRLPQARDRRLPGGVRVRVL
                     DPGSPEGVLLHLHGGGWAFGSADGQDERLWELARGARLAVVSVEYRLAPEHPYPAAPDD
                     CERAARWLAEHAVAEFGTDRLLIAGESAGAHLAVLTLLRLRAEHPGAYCGAQLAFGPYD
                     LAMTPSQRSFGDRALLSNTRSLQGSYEMFSPGTDAGRRRDPALSPLYADLAGLPPARLV
                     VGTEDPLLDDSVLLARRWREAGGAARLDVVAGAMHGFTLYPLTVTDRERRREREFLAAA
                     GR"
     gene            5475..6221
                     /locus_tag="OU787_RS29580"
                     /old_locus_tag="OU787_29580"
     CDS             5475..6221
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014152000.1"
                     /locus_tag="OU787_RS29580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_29580"
                     /product="WYL domain-containing protein"
                     /protein_id="WP_268661204.1"
                     /transl_table=11
                     /translation="MNRTARLYALVEELRAAAPRPLTVARLAARFEVATRTVQRDLQAL
                     MAAGLPVRSVTGRGGGWSIDPRTTLPPVRFTAQEAAALTVALAATDHGAPYAAAARTAA
                     QKLAAVLPADAAATARDLARRIVALPAAPAPPGAAAHRAAVEHALATGTVLRLHYADAA
                     GRSSERLVEPAGLLTAGGHWYLIAWCRTRRAGRGFRLDRITGADPTPEPAGPHDLAALL
                     RGSAAAGARPPAALGALDVIDVLDGQ"
     gene            complement(6239..7957)
                     /locus_tag="OU787_RS29585"
                     /old_locus_tag="OU787_29585"
     CDS             complement(6239..7957)
                     /GO_function="GO:0008171 - O-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042: O-methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018535100.1"
                     /locus_tag="OU787_RS29585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_29585"
                     /product="methyltransferase"
                     /protein_id="WP_268661205.1"
                     /transl_table=11
                     /translation="MTTTAAAPATDTELLRAAAEHVRRHDTAALLRALLPGLDGVELRA
                     LTDRCRFAHTALLVFPPDAGALHRMLADAGLPADAPARPSTVVRERLAARHGRDAPGLE
                     VGILRPPVTGADGEQRVVEVFALAVPPGSDLSELAELERELQHEAHLGFEVDRPDPLVL
                     RGLCALWERHGARPDGGGYNPHEDGTVLYFTAPAGSKAGFARVELYAPGDHRELLAEHL
                     ARHRAGQPAEALLRQLTGAWTTQALAAFAELGVPEAMDQQLPRSAEQLAQAVGADPETL
                     RSLLRYLAMLGAVVQDGGGFRLAPSGELLRADAPGSLRPLALLYAGPFYRSFGELAGTV
                     RTGQVAFDRLFGENHFDHFARDPYLAELFDRSMAASTRMFDPLPNHPAVRAAAAASTPG
                     APRTVVDLAGGTGELLTRLLTAHPALHGALLERPQVADAAREFLAQAGCGDRTECLPGE
                     FADVPPGGDVYVLSRVLHDWTDERCREILRHLSAAMPAHADLLVVERLLPEDDSPSLAT
                     AWDLHMRCNVGGRERTAEHYARLFADAGLELVGHDPLPLDAHVLHVRKSAPASRI"
     misc_feature    complement(8389..8403)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.06"
                     /tool="antismash"
     misc_feature    complement(8456..8476)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.51"
                     /tool="antismash"
     gene            8555..9679
                     /locus_tag="OU787_RS29590"
                     /old_locus_tag="OU787_29590"
     CDS             8555..9679
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="OU787_RS29590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_29590"
                     /product="cytochrome P450"
                     /protein_id="WP_051817038.1"
                     /sec_met_domain="p450 (E-value: 1.9e-12, bitscore: 45.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLENPYPHYARLREEHPIFWHEGMKSWVLTRYQDCRDVLRNHEVF
                     ARDRRRTGEEIPEFRQSLQTLDPPAQAPMRSLIMNAFHAQDLPGVGLRARRRTAGILDA
                     LAERDSFDLMREVAAPLALSITADLLGVREPDPDDYAEISAAIAERMDAGLKPENAARG
                     DRARTRLNALAEEWFADADDRPGVLRDVKQRAVKADLPPHYISNSTGMMFNASYGTVYA
                     TVGNVVLTLLQRPGLLQEFEDARLLTPGVNELIRYDGPAQGTSRVATRTVEIHGTTVRP
                     GQIVLTLMAAANRDPREFPHPDTLLLDRTPNRHLGFGWGTHACVGAVFGQVAIRELIVC
                     LLGAPGRLRLAGPPTRRPTATVRSLDVLPVAIDR"
     misc_feature    8558..8573
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.36"
                     /tool="antismash"
     gene            10001..11146
                     /locus_tag="OU787_RS29595"
                     /old_locus_tag="OU787_29595"
     CDS             10001..11146
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     guanidinotides: pgm_amidino"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018535871.1"
                     /locus_tag="OU787_RS29595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_29595"
                     /product="glycine amidinotransferase"
                     /protein_id="WP_030460665.1"
                     /sec_met_domain="pgm_amidino (E-value: 1.7e-184, bitscore:
                     611.4, seeds: 95, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLNSHDEWSPLKEIVVGSAANYTSHDRELSFDLFFHENLFRSDW
                     AYPRLRQNAHGPVGDRAWRIKQQYAEELHEDVEGLADTLTALGVTVHRPVPLPPDADPI
                     AGFGWNAAPVPPLNLRDNTLILGDEIIETAPAIRSRYLETRLLAPVFTEYFRRGARWST
                     MPRPVLTDASFDLSYARDTETTLGGPTEPISAPRPSPYDVGFEMMLDGAQCLRLGRDLI
                     VNIANANHAAACDWLERHLGGTRRVHRVHRMSDNHIDSMLLALRPGLFLARHEGLRDLL
                     PEPFRRWKLIVPPQPEEANFPVYDDGDLVLTTPYIDLNVLSVGPDRVLVNEACPELVKV
                     LEHEGFTVVPVRHRHRRLFGGGFHCFTLDTVRTGGLEDYAA"
     gene            11169..12494
                     /locus_tag="OU787_RS29600"
                     /old_locus_tag="OU787_29600"
     CDS             11169..12494
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     guanidinotides: pgm1"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF037360.4"
                     /locus_tag="OU787_RS29600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_29600"
                     /product="hypothetical protein"
                     /protein_id="WP_268661206.1"
                     /sec_met_domain="pgm1 (E-value: 1.8e-144, bitscore: 480.1,
                     seeds: 80, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLLIANEVDPMLSWVDFRSYSQRLLWFAEDGDVLVLPVAPPAAF
                     LRHATSLTGTDPASLTFLVPPPGRYQGKVIDPYSLLDPDFLDRTAEALAAAPGPATGLL
                     SCWPSPLVPRYAAALGLRHLVPGAAFIDQGGGELANSKAEFRAIAAAAGVPTAPGAVCR
                     SSHEAAREIPRLLAGTGAVLVKQAHNGAGAGNQLVVRDDDHRTDHVGAKLLHRLAPGPD
                     AIAHYLAEHWAWASRDDRYPVVVEEFQPASRTVYAEYLAEDTGVRPTATGELDYRERRL
                     VRESTPARGLPADVRQRLLAGAARLAEAYRSLGYRGHLSADAVVDATGRLVFTELNARV
                     TGSLHLYGPIAGRVVDTTRHPGLSVTQHRTPAHWPALDLDDFLAAATAADCAYRPETRR
                     GVLVSLPSVPGVRGGFDFCVVHRDRAEEDDVLRRLDGALCPS"
     gene            12482..13732
                     /locus_tag="OU787_RS29605"
                     /old_locus_tag="OU787_29605"
     CDS             12482..13732
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF017760.4"
                     /locus_tag="OU787_RS29605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_29605"
                     /product="MFS transporter"
                     /protein_id="WP_268661207.1"
                     /transl_table=11
                     /translation="MPVLTTRLLLDTAPLRDSPAFRRLWLGQGLSQIGGQMTVFAVALQ
                     VYRLTGSSAAVGALGLAVAVPVVLFAAVGGSLGDRTDRRRLVLWTSSLQAGVSVLFAAQ
                     ALAGLHSTGLLYLLVALQSLVGSVNAPARRACTPRLLPRRQLAAAAALNALTMQFGAVA
                     GPACAGLAAATWGLTACYLLDALSFAAALYGIARLPAMPPQGDRPPGRLAGAGEALALV
                     RSRGELAGAFLADLCIALVASPAALLPALCAERFGGHPQTLGLLAAAGAVGGVLASACS
                     GPAGRIARPGGAALLCCAAYGATVAALAVTRSLETALLLLALAGAADTLAVVFHSTVVQ
                     LSTPDRLRGRISAVEFVVGVGGTQLGRLRAGTLGALLGTGTAMLGGGLAAVAAAALVSV
                     AAPAFTHYRAADAPAEA"
     gene            13758..15152
                     /locus_tag="OU787_RS29610"
                     /old_locus_tag="OU787_29610"
     CDS             13758..15152
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="OU787_RS29610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="OU787_29610"
                     /product="hypothetical protein"
                     /protein_id="WP_268661208.1"
                     /transl_table=11
                     /translation="MRVVLIGARSEAIEALLADGHTVSLLYEGGEHRRVDPYRDRLAHA
                     CAVDSYLVVESLWSALHHVGALGPAGPDGDGDGDGADGSVDAVVSVQEHGMVPAALLGR
                     LLGARAIDPQVALRCRDKALQKAAWRAAGIPTADWAVVPDAGRGSVARAAAAAGVAAPY
                     VVKPTAGAATIGVAAADGPAELDALAAELVAQSETRRRLLVEHRVPGEEWHLDGLVRDG
                     ALAALLVSRYLVPLIETKRGRPAATVSLPPADHPALYREAAELTGRALAALGHRDGVFH
                     FEVFGGPGGFTAGELAARPGGHMIGALAERVLGIDLWAAAVRAVTGERPDRGGGPADPG
                     GLPESGGSAGRVVGFTDIPTLAGAVNRIGREHVERIPGVVDVEIKIKPGEVMPAMDANS
                     GIRIGTALVEAATEQDCRDALLRIADLAAELNSAPEPGSGPDSGPGSPQKQPPPQLRTS
                     PDHKEE"
     gene            15162..16160
                     /locus_tag="OU787_RS29615"
                     /old_locus_tag="OU787_29615"
     CDS             15162..16160
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018523577.1"
                     /locus_tag="OU787_RS29615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_29615"
                     /product="phosphotransferase"
                     /protein_id="WP_268661209.1"
                     /sec_met_domain="APH (E-value: 6.3e-23, bitscore: 80.6,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYQPIDRAPGAFQQAVPPQAIEEMCRRAFGPGAEVLAAVELGGG
                     MYNSTYRLEFADGRQTVLRVAPEPDRQFRSERALMRNEYATVPYLAPVAHLVPRVLAAD
                     FTHQVLGRDHLFQTFLDGLPAPQGLPLHPRPAWRGFYAQLGTVAREIHGVRGPWFGPVA
                     GPGHRTWSEAVLAGLADTAADLADTGTPFDDVEELIALAGRHRAVLDRITEPRLLHGDL
                     WNINLMIAADAPAPVITGVLDCDRAHWGDPEADWTIFMAARRPGTERDAFWDTWGPLAG
                     DPEAAWRRLLYTARHLAAVRLESVRLADPEQAAATVDDLRALLDRLAPGVR"
     gene            complement(16288..17481)
                     /locus_tag="OU787_RS29620"
                     /old_locus_tag="OU787_29620"
     CDS             complement(16288..17481)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014139518.1"
                     /locus_tag="OU787_RS29620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_29620"
                     /product="winged helix DNA-binding domain-containing
                     protein"
                     /protein_id="WP_268661210.1"
                     /transl_table=11
                     /translation="MAVRPLFDDDQRRARLARRHRLAPGTAADRAEQVVDDLVAVHATD
                     PATVFLAVAARLAAPGTADTERALYADGTVLRRHGMRKTLFVVPADLAPALYASTTAKA
                     AAAERTRLLKDFAASGRDAAWTAGAQDAVLAALTAALPDSPDGLTGSQLGDLVPQLRES
                     IDYGVGTSYQTAQPVGMRLLRLLGMEGTLVRRRPLGGWTSSRHRWVPGPPLPAAPSAAE
                     RAAAQAELAGRWLASHGPATEDDLVWWTGWGVREVRAALAACAAVEVELSGGATGFVLP
                     DDLAPVADPAPWAALLPALDPTAMGWKHRDWYLSPEHRPDLVDRSGNLGPTAWWNGRIV
                     GGWAQRPDGEVRLGLLTDPGPEARTALAAETAALRTLLADTRVTPRFRTPLERRLGD"
     misc_feature    complement(18064..18078)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 25.19"
                     /tool="antismash"
     misc_feature    18065..18079
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 26.06"
                     /tool="antismash"
     misc_feature    complement(18169..18183)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 30.11"
                     /tool="antismash"
     misc_feature    18170..18184
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 30.11"
                     /tool="antismash"
     misc_feature    18189..18203
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 21.9"
                     /tool="antismash"
     gene            18320..20479
                     /locus_tag="OU787_RS29625"
                     /old_locus_tag="OU787_29625"
     CDS             18320..20479
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0030245 - cellulose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015613099.1"
                     /locus_tag="OU787_RS29625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_29625"
                     /product="glycoside hydrolase family 6 protein"
                     /protein_id="WP_268661211.1"
                     /transl_table=11
                     /translation="MSTTAAHAATRVDNPFVGAGVYVNPEWSANAAAEPGGSAVANQPT
                     FVWLDRIAAINGVNGGMGLRDHLNAAVKQAAGKPYVFQVVIYDLPGRDCAALASNGELG
                     PTDLPRYESEFIDPIAAILADPAYANLRIVTTVELDSLPNLVTNAGGTNTSTTNCETMK
                     ANGNYINGVGYALNKLGAIPNVYNYVDAGHHGWLGWDSNLQPAIDVIKQAATASGSTLN
                     NVQGFVVNTANYGALHEPNFSVTDSVNGTTVRQSKWVDWNNYVDEASFAKAWRTKAIAS
                     GFNSNIGMIIDTSRNGWGGANRPTGPGPKTTVDAYVDGSRIDRRFQTGNWCNQSGAGLG
                     ERPKAAPEDGIAAYVWVKPPGESDGASSAIANDEGKGFDAMCDPTYTGNARNNNNMSGA
                     LPNAPLAGHWFSAQFQELLKNAYPALGTSTGDTTAPTAPTGLAATATSSSVALTWTAST
                     DNVGVTGYDVYRGGTLIGSTNSTSFSDTGLSASTAYSYTVKAKDAAGNVSAASAALSVT
                     TSAGGTTDTTAPTAPTNLAATTTSSSASLTWGASTDNVGVTGYNVYRGGTLIGSTTSTS
                     YTDSGLSAATAYSYTVKAKDAAGNLSAAAAVTATTQAGTGTGSAGCTATYKVSSDWGAG
                     FNADVTVTAGNTAIKSWKVTWTYAGNQQVTNLWNGTVSQSGQSVTVNNAGYNGAVAANG
                     TTSFGFGASYSGSNAVPTLTCTATS"
     gene            complement(20629..22422)
                     /locus_tag="OU787_RS29630"
                     /old_locus_tag="OU787_29630"
     CDS             complement(20629..22422)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009995711.1"
                     /locus_tag="OU787_RS29630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_29630"
                     /product="glycoside hydrolase family 15 protein"
                     /protein_id="WP_268661212.1"
                     /transl_table=11
                     /translation="MGGRIEDYALLSDLQTAALVGRDGSVDWLCLPRFDSPSCFAALLG
                     TPEHGAWRIAPVGAGDCTGRRYLGDTLVLESRWRTPDGEVKVTDLMPHRDRAPRLVRIV
                     EGVSGAVPVRGELRLRFHHGRVDPWVRRTEHHRVAVAGPDAAWLRVPPGVHTYGANGSA
                     AGPGTGAGLATVSEFTALPGVRVPFVLTWQPSHLATAPRTDPEALLAATLADWRAWAGQ
                     LSYRGEWRDAVLRSLLTLKALAYEPTGGIVAAPTSSLPEVPGGERNWDYRFCWLRDSAM
                     TLSALLRGGFRQEAAAWRKWLLRAVAGDPSDVQAVYGVAGERGLPETEADWLPGHLGSR
                     PVRFGNAAVGQLQLDVYGEVVDTLDLALRAGLPMERQVWGLLRTLLGSLAARWREPDEG
                     LWEVRCGRRQFTHSKVMAWVAADRAVRMAEATGLPAPLEQWRALRDAVHAEVCERAVDP
                     RRKVFVRSYGATELDAATLFVATTGFLPPDDERVVRTVEAVRRDLDHGGLVRRYRTGAA
                     DGLTGSEGAFLACSFWLADALAVIGRRAEARELFVRTASLANDLGLLSEQWDPLARRQL
                     GNTPQAFTHVALVNTAFRLGS"
ORIGIN
        1 tcgaagtagt gctccatcgc ccggtagcgc gggtgggtgg cgagcatccg gcgctcgcgg
       61 tccatcggat cggtaccgct gccggtcagc cgcaggccct cggcggccag cgccgcccgc
      121 agcaccgcct ggtcggcgct cagtccggcc gcgcagtcgg ccgggtcggc ggcgggcggg
      181 gagctgagct cgacctgccc gccgggttcg cgcgtcagcc gcgagcccgc cgggagcacc
      241 gggccgtcgg ccgagtcggg cagcaccgcc agcgcggccg ccacccggtc gggatccacc
      301 ggggagcccg gacatcggac gtcgtggacg aaccactccg cctcgacccc gaccagcgcc
      361 gggggcccga tcttgaagca gatggcgccc aggtgccgtt cggccgacgc ctcggtcaac
      421 tccgcccgaa gcgtcacgct gtgtaccgga tcggcggtcg gagcggcctg ttgcggacgt
      481 acagatgtca ccgggtttca ccatccctcg gttcgcgact tgagcccggt tgttcctgct
      541 cagtctgctc cggggcaaac ctcgatgccg cccggatcgc ctattcgcag gtcagccggg
      601 tgagggcggt gcggagacgg tccaacggca gggcgaaatt cagccgcagc cgcccggaac
      661 cggccgctcc gaaatccgca ccgtccgcca gctcgacatg acgctcggtg agcagctcct
      721 cccggctgcc gagccccgca ccgtccagcc acagcaggta cgaggactgc ggacgggcca
      781 gcaccgcacc gcccagcgcc cccaccgcca actcccgggc ccgcaccagg tgccccagca
      841 gcccgtccag ccacggcccg ccctcggcca gcgccgcccg ctgcgcgacc gcccccagca
      901 gcccgccctc ccacagcccg aaacccgcca tcaccgccgc cagccgctcc cgcagccccg
      961 cgtccggcac cagcgcgaaa cagctcggca ggcccgagac gttgaaggtc ttgccgaccg
     1021 agttcagcgt caccacgttc gccgccccgc ccgtcaccgc caccgcgacc ggctgcgccg
     1081 cgcccgcgtc cgggtgccgc aggtcgccgt gcacctcgtc cgagaccagc agccccggcg
     1141 cggccgccgc ggccagcgcc cggacgtccg cggccggcca gatccgcccg gacgggttgt
     1201 gcgggctgct cagcagcacc aggcccggcc gggccgccgc gacctcggcc aacggcagcc
     1261 ggtacgggtc ggccggatcg ccggtctcca gcagcggcag ctcccgcacc gccacccccg
     1321 ccgccccgca gacccgggcg aacccgcccc actccggcgt cacgaacacc gccggaccgg
     1381 acagcggccg caccgcctcc agcagcagcc gcaccgccgt gcccggcgcg aacggcagca
     1441 gcatcaccca gcccggatcc acctccaccc cgtgccgccg ccggtaccag tccgccacca
     1501 gcacccggtc cgcggcctcc gccaccgggt acccgaacgc cggatgcccc gcccgcaccc
     1561 gcaacgccgc ccccaccgcg ggcggccccg gcaggtccat gtccgccacc cccatggcga
     1621 tccgccccgc acccgcccgc gcccacttcg cgctgcccgt ccccgcccgc gagaaccgtc
     1681 cgaacaccga gtgctccctc cgtcgccgcc gccgtccccc tcacgctagg cccgcaccgg
     1741 tgagcggggg cagtgtgcgc ggcgggccgg gccgtcgaga actgaatcgg tacgtgtctg
     1801 tgaactggca ctcagtgagg aatttcgcca tggattactt aaacattgct taacaactat
     1861 cggctttcgg aaacgtggcc ggaatccctg gacaacgttg tccgatgccg cgcagactgg
     1921 acccacccat cgcacccgtg gtcgaaccgc ggtaggccgg acccaccttg cgaggcaccc
     1981 catgccgaag aacagcaccg ccatctacct gcgctgctac cccgaggacc gctgggagat
     2041 gatgtcccac cgccacgccc tcgagggcct ggccgaccgc cgcggactgg cccgcccgat
     2101 cctctacctg gacaacggca cccgctccac cgaacgcgcc ccccgcctcg aacacctgct
     2161 cgccgacatc gccgtcggct gggtcgacac cgtcctgatc cccggcacct gggtcttcgc
     2221 cctctgcccc accaccgccc gcaccaccgc cgaccggatc cgcaccaccg gcgcccacct
     2281 gatcgaaatg acctcccccc gcgccatcct ccaagccgcc tgaccacccg aaacgacacg
     2341 aggcccctcg cggaggaagg gcctcgggcg gcgggtgggc gggggagtca gacctcgccg
     2401 aactctccgg cggcggcggc gcggcagaag gcgttccaca cggcgggcgg gaaggtcagg
     2461 atcgggcccc gggggtcttt tgagtcccgg acgtggcccg ggtgggcgtc gtcgacttcg
     2521 atgcactgac cgccgtccga gttgctgtaa ctgctcttgc gccaacggcg gtcatcggca
     2581 ggtgacttga ggtcggcatg agccatcggg ggtcagtcct tcctcgtggg gcgaggcccc
     2641 tcgcggagga aggggcctcg ggcggcgggt gggtggggga gtcagacctc gccgaactct
     2701 ccggtggcgg cggcgtggca gaaggcgttc cacgcggcgg gcgggaaggt caggatcggg
     2761 ccctgggggt ccttggagtc ccggacgtgg ccggggtggg cgtcgtcgac ttcgatgcac
     2821 tcgccgccgt cggagttgct gtagctgctc ttgcgccaac ggcgttcatc cgtgggtgac
     2881 ttgaggtcgt catgagccat cggggattag tccttccatc gcagctctga tcagtcgctc
     2941 ggactcggcc ttggacagcg cctgagccct caatagatcg tagagtgccc ggcgttctgc
     3001 tacatcacgc tcttcttcga agaagactcc ggcccgggtg ctctcctcgt atgccacctg
     3061 ccggttgtcc tccagcctga ggatggacat ggaggaggtc tcggagtgga cgccggcgga
     3121 gaaggggagc acctgcacca cgacgttcga cagttgagcc gccgtaagga tggcggtcag
     3181 ctgctccgtc atctcggccg gagtcccgat ctgacggcgg atcgcggcct cgtcgaggat
     3241 gaaccagtac cggcactctg cgctgttgta catgcggatc tgtcgttcaa gccgagcctg
     3301 gacccgctgc tcgacctctt cgtccgggcc ataggggatg ccggaacgga ggatgcgccg
     3361 ggcacaggct tcggtctgga gcaggccgtg gataccaggg ctgtaggact cgtacaccct
     3421 ggcgctgtcg gccagggaaa ggaactcctg gtacttcgcg ggatggcttt cctgtcgggc
     3481 cagcgggaac atccgggcga agaagccgtc ggtcatgagg acgctgtcga gctgctccga
     3541 aaggctgtcg ggaaccctga tgtccccgtt ctccacccgg gacatcgtgc tcggggagaa
     3601 gtgcacctcc tcggcaagcc tggccagtga ccacccccgc tccgtccgga gccgtcggat
     3661 ctcggcgccg tagaagtgcc gggcgctctt gctcggatcc acctcgcgtt ccggccaggc
     3721 catgtccgcc cctttcccca gatgcttcgt gaggctccgt cgacacgcgc agaagcggag
     3781 agccccgccc ttccgacttt ccgatccttc acagcgtagc gccgatcagc gaccgccgga
     3841 gcacggacag tgaccatcgt ggaggccaaa cgccctgcgg agcaccgcgc ctgacgagcc
     3901 gtcatgtctt ccgctcctgc cggctcgttc aaccggcggc cgatggagat cgtccctgct
     3961 cagaggggtg gtcggccttg tctatgctca tctccatggc acttgaatgg gaacagatca
     4021 tggtcgactc cgccgacccc atcaccctcg gacgctggtg ggccgaggct ctcggatggg
     4081 tcgtggtcga cgagaccgag gagatcatcg agatccggcc cgagccggac cggatgccgg
     4141 ggctgctctt cgtcggcgtc cccgagggca agacgacgaa gaacaggctc caccccgatt
     4201 tccgccccga cgaccaggag gccgaggtct cccggctgat ctccctcggc gcccggcgcg
     4261 tcgaccccgt gcaggacggg cagcactggg tgaccctgct cgacccggag ggcaacgagt
     4321 tctgcgtcct gagtgcaccg aagggctgag cgggccccgg cagcccgccc agtgacccgg
     4381 atcacccgga aagggtgaca cgccgctgtc gccacgcccc ggcatcgtct gcggcatgac
     4441 gacgacgcac cgcaccacgc ccgacttccc cgactgccct aacttccccg acttcctgcg
     4501 cggcgagccc ctcgacgggc accccctgcg cgcccacctg cgggacctcg actgcctgga
     4561 ggagacgctc gccttcaacc gggccttcga acgggccgcg ggcagccggc ccgtccgccg
     4621 cggaccgctc gacgcggaga cgctcgcccg gctgcgccgc aaccggctcg ggggtgacac
     4681 gccgccccgg cgtcttccgc aggcccggga ccggcggctc ccgggcgggg tgcgggtccg
     4741 ggtgctcgat cccggcagcc ccgagggcgt cctgctccat ctgcacggcg ggggctgggc
     4801 gttcgggtcg gcggacgggc aggacgagcg gctgtgggag ctggcccggg gggcccggct
     4861 ggccgtcgtc agcgtcgagt accggctcgc ccccgaacac ccctaccccg ccgcccccga
     4921 cgactgcgag cgtgccgccc gctggctcgc cgagcacgcc gtcgccgagt tcggcaccga
     4981 ccggctgctg atcgcggggg agtcggccgg cgcgcacctc gccgtcctca ccctgctgcg
     5041 cctgcgggcg gagcatcccg gggcctactg cggagcccag ttggccttcg gcccctacga
     5101 cctggccatg acccccagcc agcgcagctt cggcgaccgt gcgctgctga gcaacacccg
     5161 cagtctgcaa gggagttacg agatgttcag ccccggcacc gatgccgggc ggcgccgtga
     5221 cccggcgctg tccccgctct acgcggacct cgccggtctg ccgccggccc ggctcgtggt
     5281 cggcaccgag gacccgctgc tggacgactc ggtgctgctg gcccggcgct ggcgggaggc
     5341 gggcggggcg gcccggctcg acgtggtggc cggggcgatg cacggcttca ccctctaccc
     5401 gctcaccgtc accgaccgcg aacgccgccg cgagcgggag ttcctcgccg ccgcgggccg
     5461 gtagggtcct ccgggtgaac cgaacggccc gcctgtacgc cctggtcgag gagttgcggg
     5521 ccgccgcgcc ccgcccgctg accgtcgccc ggctggcggc ccggttcgag gtcgccaccc
     5581 gcaccgtcca gcgcgacctc caggccctga tggccgcggg cctccccgtc cggtccgtca
     5641 ccggacgggg aggcggctgg tccatcgacc cgcgcaccac cctgccgccg gtccggttca
     5701 ccgcgcagga ggccgccgcg ctcaccgtcg cgctcgccgc caccgaccac ggcgcgccct
     5761 acgccgccgc ggcccgcacc gccgcgcaga aactcgccgc cgtcctgccc gccgacgccg
     5821 ccgccaccgc ccgcgacctg gcccgccgga tcgtcgccct ccccgcggca cccgccccgc
     5881 ccggcgccgc cgcccaccgg gccgccgtcg aacacgccct cgccaccggc accgtgctgc
     5941 gcctgcacta cgccgacgcc gccgggcgga gcagcgaacg cctggtcgaa ccggccgggc
     6001 tgctcaccgc gggcggccac tggtacctga tcgcctggtg ccggacccgc cgggccggcc
     6061 gcggcttccg cctcgaccgg atcaccggcg ccgacccgac ccccgaaccg gccggcccgc
     6121 acgacctcgc cgcgctgctg cgcggttcgg ccgcggcggg cgccaggccg cccgccgcgc
     6181 tcggcgcact tgacgtcatc gacgtactcg acgggcagtg aggtgagctg gcggagcgtc
     6241 agatccggga agcgggggcg gacttgcgca cgtgcaggac gtgggcgtcc agcggcagcg
     6301 ggtcgtggcc gaccagttcc agccccgcgt ccgcgaacag ccgggcgtag tgctccgcgg
     6361 tgcgttcccg gccacccacg ttgcagcgca tgtgcaggtc ccaggcggtg gccagggagg
     6421 gggagtcgtc ctcggggagc agccgttcca ccaccagcag gtccgcgtgc gcgggcatcg
     6481 cggccgacag gtgccgcagg atctcccggc agcgttcgtc cgtccagtcg tgcagcaccc
     6541 gcgagagcac gtacacgtcc ccgcccggcg ggacgtccgc gaactcgccc ggcaggcact
     6601 ccgtccggtc gccgcagccc gcttgggcca ggaactcccg ggccgcgtcc gcgacctgcg
     6661 ggcgttccag cagcgcgccg tgcagcgccg ggtgcgcggt cagcagccgg gtcagcaact
     6721 cgccggtgcc gcccgccagg tcgaccaccg tgcgcggtgc gccgggggtg gaggcggcgg
     6781 ccgcggcccg caccgccggg tggttcggca gcgggtcgaa catccgggtg ctcgccgcca
     6841 tcgaccggtc gaacagctcg gccaggtacg ggtcccgggc gaagtggtcg aagtggttct
     6901 cgccgaacag ccggtcgaac gccacctgcc cggtccggac cgtcccggcc agctcgccga
     6961 acgaccggta gaacggcccc gcgtacagca gcgccagcgg ccgcagcgaa cccggcgcgt
     7021 cggcccgcag cagttccccg gacggggcga gccggaagcc gccgccgtcc tggaccaccg
     7081 cgcccagcat cgccaggtac cgcagcagcg agcgcagggt ctccgggtcc gcccccactg
     7141 cctgggccaa ctgctcagca ctgcgcggga gttgctggtc catcgcctcc gggacgccca
     7201 gctcggcgaa ggccgccagc gcctgcgtgg tccacgcccc ggtcagctgc cgcagcagcg
     7261 cctcggcggg ctgcccggcg cggtgccggg ccaggtgctc cgccagcagc tcccggtggt
     7321 cgccgggcgc gtacagctcg acccgggcga agcccgcctt cgagccggcc ggtgcggtga
     7381 agtacagcac cgtgccgtcc tcgtgcgggt tgtagccgcc gccgtccggg cgcgcgccgt
     7441 gccgctccca cagcgcgcac aggccgcgca gcaccagcgg gtcggggcgg tccacctcga
     7501 agccgaggtg cgcctcgtgc tgcaactccc tttccaactc ggcgagttcg gacaggtcgg
     7561 agcccggcgg cacggccagc gcgaacacct cgaccacccg ctgctcgccg tccgccccgg
     7621 tcaccggcgg ccgcaggatg cccacctcca gccccggggc gtcccggccg tgccgggccg
     7681 ccagccgctc ccgcaccacc gtgctcggcc gggccggggc atcggccggc agcccggcgt
     7741 cggcgagcat ccggtgcagc gcgccggcgt ccggcgggaa gaccagcagc gcggtgtgcg
     7801 cgaaccggca gcggtcggtc agtgcccgca gctccacccc gtccagcccg ggcagcaggg
     7861 cgcgcagcag ggcggcggtg tcgtgccggc ggacgtgctc ggcggcggcc cggagcaact
     7921 ccgtgtcggt ggcgggcgcg gcggcggtgg tggtcatggc gaagtgtcct ccggcagggt
     7981 cagggagcgg gtgatgcgtg ggcgaaacgt ttctggcggg ggaggggtga gaggaggacg
     8041 cgccaccgac gcgagcgcga gcgcgaacgc gggcgcgggc aggagcgggc gcgggcacgg
     8101 gcgcgggtgg gcacgggtag gcccgagcag cgtgcatgcg tgcgtgcgtg cggatgcgca
     8161 aggcgccgtc ccccgatgtt cccccgaatc ggtctgacgc gacgtcagcc ccggtgatcc
     8221 taaccgcagt cggagcggcg cccggcccgg cttcacccga tcggcccgcc gcccgcaccg
     8281 acccgccgcg agccccggcc gcggcgcgcg acacttccgg acatttgcgg acggaatact
     8341 tccgtccggt gctatcgcaa tactttcctg gggactcttg ccagggtcat gtcgcattga
     8401 taaattcgct tacggcgcac aagaccggtc cggcgacaga cgatcattcc tggcgcattc
     8461 atcatgcgga ccaaatcatc accaactcct tgcaaaacag gcaaccgttg ggaattgtgc
     8521 tgtggacccg cactacgatc cgctggatcc ggccatgctc gaaaatccct atccgcacta
     8581 cgcccggctg cgcgaagaac acccgatctt ctggcacgag ggcatgaagt cctgggtcct
     8641 gacccgctac caggactgcc gggacgtgct gcgcaaccac gaggtgttcg cccgcgaccg
     8701 gcggcgcacc ggggaggaga tccccgagtt ccgccagagc ctgcagaccc tcgacccgcc
     8761 cgcgcaggcc ccgatgcgct cactgatcat gaacgcgttc cacgcccagg acctgccggg
     8821 agtgggactg cgcgccagac ggcgcaccgc gggaatcctc gacgcactcg ccgagcgcga
     8881 ttccttcgac ctgatgcgtg aagtcgccgc accgctcgcg ctttccatca ccgccgacct
     8941 gctgggcgtc cgggaacccg atcctgatga ttacgccgag atatccgcgg ccatcgccga
     9001 acgcatggac gccggcctca agcccgagaa cgccgcccgc ggcgaccgcg ccagaaccag
     9061 gctgaacgcg ctggccgagg agtggttcgc cgacgcggac gaccggcccg gggtgctccg
     9121 ggacgtcaag cagcgggccg tcaaggccga cctcccgccg cactacatct ccaacagcac
     9181 cggcatgatg ttcaacgcca gctacggcac ggtctacgcc acggtcggca acgtggtcct
     9241 caccctcctg caacgccccg gcctgctcca ggagttcgag gacgcgcgac tgctcacccc
     9301 cggcgtcaac gagctgatcc gctacgacgg ccccgcccag ggcaccagcc gggtcgccac
     9361 ccggacggtc gagatccacg gcacgaccgt ccggcccgga cagatcgtgc tgaccctgat
     9421 ggcggcggcc aaccgcgacc cgcgcgaatt cccccacccc gacaccctgc tgctcgaccg
     9481 cacccccaac cgtcacctgg ggttcggctg gggaacgcac gcgtgcgtcg gggccgtgtt
     9541 cggccaggtg gcgatacggg agctgatcgt ctgcctgctc ggcgcacccg ggaggctccg
     9601 cctcgcgggc ccgccgaccc ggcgcccgac ggcgaccgtt cgcagcctgg acgtgctccc
     9661 ggtcgccatc gaccggtgag cagtccggca gcccgccccc gacaggggcc ccggcaggga
     9721 aggagcgcgc catgagctac gaccactgaa ccccgtcccg cagcaccgac cgagcagacg
     9781 ttgtgaacag gcgtcgtgaa cggacgtcat gagcggacgc cgtgaacagg cgtcgtgagc
     9841 agacgtcaga cgtggggccg gcgcaccgcc cgacgcggca cgccggcccc acccacggac
     9901 cagcccacgg ccccacccac ggatcagccc acggccccac ccacggaccc gcccaccagg
     9961 cgaaagtgac cagccagccc accacgcgaa agagtggccc atgcagctga acagccatga
    10021 cgagtggtcg ccgctgaagg agatcgtcgt cggctccgcc gcgaactaca cctcgcacga
    10081 ccgcgagctc tccttcgacc tgttcttcca cgagaacctg ttccgttccg actgggccta
    10141 cccccggctg cgccagaacg cccacggccc ggtcggcgac cgcgcctggc ggatcaagca
    10201 gcagtacgcg gaggaactcc acgaggacgt cgagggcctg gccgacaccc tcaccgccct
    10261 cggcgtcacc gtgcaccgcc ccgtcccgct gccccccgac gcggacccga tcgccgggtt
    10321 cggctggaac gccgccccgg tgccgccgct caacctgcgc gacaacacgc tgatcctcgg
    10381 cgacgagatc atcgagaccg cgcccgccat ccgctcccgc tacctggaga cccggctgct
    10441 ggccccggtc ttcaccgagt acttccggcg cggcgcccgc tggtccacca tgccgcggcc
    10501 ggtcctcacc gacgcctcct tcgacctctc ctacgcccgc gacaccgaga ccaccctcgg
    10561 cgggccgacc gaaccgatct ccgccccccg accctccccg tacgacgtcg ggttcgagat
    10621 gatgctcgac ggcgctcagt gcctgcggct cggccgcgac ctcatcgtca acatcgccaa
    10681 cgccaaccac gccgccgcct gcgactggct ggaacgccac ctcggcggca cccgccgcgt
    10741 ccaccgggtg caccggatga gcgacaacca catcgacagc atgctgctgg ccctgcgccc
    10801 cggcctcttc ctggcccgcc acgagggcct gcgcgacctg ctgccggaac ccttccgccg
    10861 ctggaagctg atcgtgccgc cacagcccga ggaggccaac ttcccggtct acgacgacgg
    10921 cgacctggtc ctgaccaccc cctacatcga cctcaacgtc ctctcggtcg gccccgaccg
    10981 ggtcctggtc aacgaggcgt gcccggaact cgtcaaggtc ctcgaacacg agggcttcac
    11041 ggtcgtcccg gtccggcacc ggcaccggcg gctgttcggc ggcggcttcc actgcttcac
    11101 cctggacacc gtccgcaccg gcgggctcga agactacgcg gcctgaaccg gcggaacggg
    11161 accacgacat gcgcctgctg atcgccaacg aggtcgaccc gatgctgtcc tgggtcgact
    11221 tccggtccta ctcgcagcgg ctgctctggt tcgccgagga cggcgacgtc ctggtgctgc
    11281 ccgtcgcgcc gcccgccgcc ttcctgcggc acgccacctc gctcaccgga accgacccgg
    11341 cctcgctgac cttcctggtc ccgccgcccg gccgctacca gggcaaggtg atcgacccct
    11401 acagcctgct cgacccggac ttcctggacc ggaccgccga agcgctcgcc gccgcccccg
    11461 gccccgccac cggcctgctg tcctgctggc ccagcccgct cgtcccgcgc tacgccgccg
    11521 ccctgggcct gcgccacctg gtgcccggcg ccgccttcat cgaccagggc ggcggcgaac
    11581 tcgccaacag caaggccgag ttccgggcga tcgcggccgc cgccggcgtc ccgaccgccc
    11641 ccggcgcggt ctgccgcagc agccacgagg ccgcccggga gatcccccgg ctgctggccg
    11701 gcaccggcgc cgtcctggtc aaacaggcgc acaacggcgc cggcgccggc aaccagctcg
    11761 tggtccgcga cgacgaccac cgcaccgacc acgtcggcgc gaaactcctg caccgcctcg
    11821 cacccggccc cgacgcgatc gcccactacc tcgccgaaca ctgggcctgg gcctcccggg
    11881 acgaccgcta ccccgtggtg gtcgaggagt tccagcccgc ctcgcgcacc gtctacgccg
    11941 agtacctggc cgaggacacc ggcgtccgcc ccaccgccac cggcgaactc gattaccggg
    12001 aacggcggtt ggtccgcgaa tccacccccg cccgcggcct ccccgccgac gtccggcaac
    12061 ggctgctggc cggcgccgcc cggctcgccg aggcctaccg ctccctcggc taccgcggcc
    12121 acctcagcgc cgacgccgtc gtcgacgcca ccggccgcct ggtcttcacc gaactcaacg
    12181 cccgcgtcac cggctcgctc cacctctacg ggccgatcgc cggccgggtc gtcgacacca
    12241 cccgccaccc cggactcagc gtcacccagc accgcacccc cgcccactgg cccgccctcg
    12301 acctcgacga cttcctcgcc gccgccaccg cggccgactg cgcctaccgc cccgagaccc
    12361 gccgcggcgt cctggtctcg ctgccctccg tccccggcgt ccgcggcggc ttcgacttct
    12421 gcgtcgtcca ccgggaccgg gccgaggagg acgacgtcct gcggcgcctg gacggggcac
    12481 tgtgcccgtc ctgaccaccc ggctgctcct cgacaccgcg ccgctgcgcg actcacccgc
    12541 cttccggcgg ctctggctcg gccagggtct ctcccagatc ggcgggcaga tgacggtgtt
    12601 cgccgtcgcc ctccaggtct accggctcac cggcagctcc gccgcggtcg gcgcgctcgg
    12661 cctggcggtg gccgtccccg tggtgctgtt cgccgccgtc ggcggcagcc tcggcgaccg
    12721 caccgaccgc cgccgcctgg tgctgtggac cagcagcctg caggccggcg tctccgtgct
    12781 gttcgccgcc caggccctgg ccggcctgca ctcgaccggc ctgctctacc tgctggtcgc
    12841 cctgcagtcc ctggtcggca gcgtcaacgc ccccgcccgg cgcgcctgca ccccccggct
    12901 gctgccccgc cgccaactgg ccgccgccgc cgcactgaac gccctgacca tgcagttcgg
    12961 cgcggtcgcc ggaccggcct gcgccggact cgccgccgcc acctggggcc tgaccgcctg
    13021 ctacctgctg gacgcgctca gcttcgcggc cgcgctgtac ggcatcgccc ggctccccgc
    13081 catgccgccg cagggcgacc gcccgcccgg ccgcctcgcc ggagccggcg aggccctcgc
    13141 cctggtacgg agccggggcg aactcgccgg ggcgttcctc gccgacctgt gcatcgccct
    13201 ggtcgcctcg cccgccgccc tgctgcccgc gctctgcgcc gaacgcttcg gcggccaccc
    13261 gcagaccctc ggcctgctgg ccgccgccgg cgcggtcggc ggcgtcctcg cctccgcctg
    13321 ctccggcccg gccggccgga tcgcccgccc cggcggcgcc gccctgctct gctgcgccgc
    13381 gtacggcgcg accgtcgcgg ccctcgccgt caccaggagc ctggagaccg cactgctgct
    13441 gcttgccctc gccggagccg ccgacaccct ggcggtggtc ttccactcca cggtcgtcca
    13501 actcagcacc cccgaccggc tgcgcggccg gatcagcgcg gtcgagttcg tggtcggcgt
    13561 cggcggcacc cagctcggcc ggctccgggc cggcacgctt ggcgccctgc tcggcaccgg
    13621 caccgcgatg ctcggcggcg gcctggccgc agtggccgcg gccgccctgg tcagcgtcgc
    13681 cgcaccggcc ttcacccact accgcgccgc cgacgccccg gccgaggcgt gagcgcgaga
    13741 cgaccaggag gactgccatg cgcgtggtgc tgatcggcgc ccggtcggag gcgatcgagg
    13801 cactgctggc cgacggccac accgtctccc tgctctacga gggcggcgag caccgccggg
    13861 tcgaccccta ccgcgaccgc ctcgcccacg cctgcgccgt cgactcctac ctggtggtgg
    13921 agtcgctgtg gtccgccctg caccacgtcg gcgcgctcgg ccccgccgga ccggacgggg
    13981 acggggacgg ggacggggcg gacggatccg tggacgcggt ggtctccgtc caggagcacg
    14041 gcatggtgcc cgccgccctg ctgggccgcc tgctcggcgc ccgggcgatc gacccgcagg
    14101 tggcgctgcg ctgccgcgac aaggccctgc agaaagcggc ctggcgggcc gccggcatcc
    14161 ccaccgcgga ctgggccgtc gtccccgacg cgggccgcgg cagcgtcgcc cgggccgccg
    14221 ccgcggccgg ggtggccgcc ccgtacgtgg tcaagccgac cgccggagcg gccaccatcg
    14281 gcgtcgccgc cgccgacgga ccggccgaac tcgacgcgct cgcagccgag ttggtggcgc
    14341 agtcggagac caggcgacgg ctgctggtgg agcaccgggt gcccggcgag gagtggcacc
    14401 tggacgggct ggtccgcgac ggcgccctcg cggccctgct ggtctcgcgc tacctcgtcc
    14461 cgctgatcga gaccaagcgc ggccgccccg ccgccaccgt ctcgctgccg cccgccgacc
    14521 accccgccct ctaccgcgag gccgccgaac tcaccggccg ggcactggcc gcgctcggcc
    14581 accgcgacgg ggtgttccac ttcgaagtct tcggcggccc cggcgggttc accgcgggcg
    14641 aactggccgc ccgccccggc ggccacatga tcggcgcgct cgccgaacgc gtcctcggca
    14701 tcgacctgtg ggccgccgca gtccgcgcgg tgaccggcga acgaccggac cgcggcggcg
    14761 gacccgccga cccgggcgga ctgcccgagt cgggcggctc ggccggacgg gtggtcggat
    14821 tcaccgacat cccgaccctc gccggagcgg tcaaccggat cggccgcgag cacgtcgagc
    14881 ggatccccgg cgtggtcgac gtcgagatca agatcaagcc gggcgaggtg atgcccgcca
    14941 tggacgccaa ctccggcatc cggatcggca cggcgctggt cgaggccgcc accgaacagg
    15001 actgccggga cgccctgctg cgcatcgccg acctggccgc cgagctcaac tccgctcccg
    15061 agcccggctc cggacccgac tccgggcccg ggtccccgca gaagcagccg cccccgcagc
    15121 tccgcacgtc ccccgaccac aaggaagagt gaaccggacc catgaagtac cagcccatcg
    15181 accgcgcccc cggggcgttc cagcaggcgg tgccgccgca ggcgatcgag gagatgtgcc
    15241 ggcgcgcctt cggccccggc gccgaggtcc tggccgcggt cgaactcggc ggcggcatgt
    15301 acaactccac ctaccggctg gagttcgccg acggccggca gaccgtcctg cgggtggccc
    15361 ccgagccgga ccggcagttc cgcagcgaac gcgccctgat gcgcaacgag tacgcgaccg
    15421 tcccgtacct ggcccccgtc gcgcacctgg tgccgcgggt gctggccgcc gacttcaccc
    15481 accaggtgct gggccgcgac cacctgttcc agaccttcct ggacgggctg cccgccccgc
    15541 agggcctgcc gctgcacccg cgccccgcct ggcgcggctt ctacgcccaa ctcggcaccg
    15601 tggcccggga gatccacggc gtccggggtc cctggttcgg ccccgtggcc gggcccgggc
    15661 accgcacctg gagcgaggcc gtcctggccg gcctggccga caccgccgcc gacctggccg
    15721 acaccggcac gccgttcgac gacgtcgagg aactgatcgc gctggccggc cgccaccgcg
    15781 ccgtcctcga ccggatcacc gaacccaggc tcctgcacgg agacctgtgg aacatcaacc
    15841 tgatgatcgc cgcggacgcc cccgcccccg tcatcaccgg cgtcctggac tgcgaccggg
    15901 cccactgggg cgaccccgag gcggactgga cgatcttcat ggccgcccgc cggcccggca
    15961 ccgaacgcga cgccttctgg gacacctggg gccccctcgc cggcgacccc gaggccgcct
    16021 ggcgccgcct gctctacacc gcccgccacc tcgcggcggt ccgcctggag tccgtccggc
    16081 tggccgaccc cgaacaggcc gccgccaccg tggacgacct ccgggccctg ctcgaccgcc
    16141 tggcgccggg cgtgcgctga caccaccgag cgtgcactga aaccgggcgt gcactggaac
    16201 cgggcgccgc cgtcccgccg ccacgggctg ccggaccccg ggcccgcccg cccgcccggc
    16261 ggtccggtcc ggcccggtcc ggtccggtca gtcgccgagc cgccgttcga ggggcgtgcg
    16321 gaagcgcggg gtgacgcggg tgtcggcgag cagggtgcgc agggcggcgg tctcggcggc
    16381 gagggcggtg cgggcctcgg ggccggggtc ggtgagcagt ccgagccgga cctcgccgtc
    16441 ggggcgctgg gcccagccgc cgacgatccg gccgttccac caggcggtgg ggccgaggtt
    16501 gccggagcgg tcgaccaggt cgggccggtg ctcgggggag aggtaccagt cgcggtgctt
    16561 ccagcccatc gcggtggggt cgagggccgg gagcagggcc gcccagggcg ccgggtcggc
    16621 gaccggggcg aggtcgtcgg gcagtacgaa cccggttgcc ccgccggaga gttcgacctc
    16681 gacggccgcg cacgcggcca gcgcggcccg cacctcgcgg acgccccagc cggtccacca
    16741 gaccaggtcg tcctcggtgg cgggcccgtg ggaggccagc cagcgcccgg ccaactcggc
    16801 ctgcgcggcg gcgcgttcgg cggcggacgg ggcggcgggg aggggcgggc cgggcaccca
    16861 gcggtgccgg ctgctggtcc agccgcccag cgggcggcgg cggaccaggg tgccctccat
    16921 gccgagcagg cgcagcagcc gcatgccgac cggctgggcg gtctggtagg aggtgccgac
    16981 gccgtagtcg atgctctcgc gcaactgcgg tacgaggtca ccgagttgac tgcccgtcag
    17041 gccgtcgggc gagtcgggga gcgcggcggt cagcgccgcc aggacggcgt cctgcgcacc
    17101 ggcggtccag gcggcgtccc ggccggaggc ggcgaagtcc ttgagcagcc gggtgcgttc
    17161 ggcggcggcg gccttcgcgg tggtggaggc gtacagcgcc ggggcgaggt cggcggggac
    17221 cacgaacagg gtcttgcgca tgccgtggcg gcgcagcacc gtcccgtccg cgtacagggc
    17281 ccgttcggtg tcggcggtgc ccggtgcggc cagccgggcc gcgacggcga ggaacaccgt
    17341 ggcggggtcg gtggcgtgca cggcgaccag gtcgtccacc acctgctcgg cccggtcggc
    17401 cgcggtgccg ggcgcgagcc gatggcgccg ggcgagccgg gcccggcgct ggtcgtcgtc
    17461 gaacaggggt cgcactgcca cgggttcctc ctccggatcg agggaccagc ctgccacgcc
    17521 cccgccccgc acccggccgc gacgcgcgaa ttcgcccggc ggcccgggcc gagggcggtg
    17581 gctcgggctc cgggaggggc ggccccgggg cgccgggagg ggcgggcgtg aaagtttcgc
    17641 gccgcgggcc ggtcggcggc gccgggcggg ccggctgcgg gggcgcggcg ggctcccggc
    17701 cgggtggaag cggggcccag ggaagtgaac gggcttgtgc aggaagcaag ttcggccgga
    17761 aagcgcccgc cgaggggcgt gtccccgcgc gcgggccggc ggcgttccgt cccgccggtg
    17821 gcaggcccgg gcggcggggc ggccccgggg tgggcggtgg cggggccgcg ggccggcgcc
    17881 ccgagtgggg cgggccgggg tgcgggtgcg ggtgcgaggg ccggggccgg tggaacctgc
    17941 tggtgcggcg gtgaaccgtg gtgcccggca ggcccgttgg gccgctggtg gcgggcggcc
    18001 cggggccggg gcgggggagc ggcggggcgg ccgcccgtgg cggacggtgc ccatcgggga
    18061 tcggcgggag cgctcccacg gtttctgtcg aacttcttga cgggagtgca aggtcatggc
    18121 ttcatatcgg ttgtccccga gctgagttcg cctcagccca ggccaagtat gggagcgctc
    18181 ccattagttg ggagcgtttc cgtcgagtcc gtcccccacc cgaaaggact cccttaccgt
    18241 gtcgtcgaac ctgacgcgcc gtctccggac ggcggcagcg gctgcggtgc tcagcgccgc
    18301 gaccgtcctc ccccttgcca tgtcgaccac cgccgcccac gcggcgaccc gtgtggacaa
    18361 ccccttcgtc ggcgccgggg tctacgtgaa ccccgagtgg tccgccaacg ccgccgccga
    18421 gccgggcggt tcggcggtcg ccaaccagcc gaccttcgtc tggctggacc gcatcgcggc
    18481 catcaacggc gtgaacggcg gcatgggtct gcgcgaccac ctgaacgccg cggtgaagca
    18541 ggccgcgggc aagccgtacg tgttccaggt cgtcatctac gacctgccgg gccgcgactg
    18601 tgccgccctc gcctcgaacg gcgagctcgg ccccaccgac ctgccgcgct acgagagcga
    18661 gttcatcgac ccgatcgccg cgatcctggc cgacccggcc tacgcgaacc tgcggatcgt
    18721 caccacggtc gagctcgact cgctgccgaa cctggtcacg aacgctggtg gtacgaacac
    18781 gtcgaccacc aactgcgaga ccatgaaggc caacggcaac tacatcaacg gcgtcggcta
    18841 cgcgctgaac aagctcggtg cgatcccgaa cgtctacaac tacgtggacg cgggccacca
    18901 cggctggctc ggctgggact ccaacctgca gcccgccatc gacgtcatca agcaggccgc
    18961 cacggcgtcc ggctcgacgc tcaacaacgt gcagggcttc gtcgtcaaca ccgccaacta
    19021 cggcgcgctg cacgagccca acttcagcgt caccgactcg gtgaacggca ccacggtccg
    19081 ccagagcaag tgggtcgact ggaacaacta cgtcgacgag gcgtccttcg ccaaggcgtg
    19141 gcgcaccaag gcgatcgcgt ccgggttcaa ctcgaacatc ggcatgatca tcgacacctc
    19201 ccgcaacggc tggggcggcg ccaaccgtcc gaccggcccg ggcccgaaga ccaccgtgga
    19261 cgcgtacgtc gacggcagcc gcatcgaccg ccgcttccag accggcaact ggtgcaacca
    19321 gtccggtgcg ggcctcggcg agcgcccgaa ggcggccccc gaggacggca tcgccgcgta
    19381 cgtgtgggtg aagcctccgg gtgagtcgga cggcgcgagc tcggccatcg ccaatgacga
    19441 gggcaagggc ttcgacgcca tgtgcgaccc gacgtacacc ggcaacgcgc gcaacaacaa
    19501 caacatgtcg ggcgccctgc cgaacgcccc gctcgcgggc cactggttct cggcccagtt
    19561 ccaggagctg ctgaagaacg cctacccggc gctcggcacc agcaccggtg acaccaccgc
    19621 gccgaccgcc ccgaccggtc tcgcggcgac cgccacctcc agcagcgtcg cgctgacctg
    19681 gaccgcctcc accgacaacg tcggcgtgac cggctacgac gtgtaccgcg gcggcaccct
    19741 gatcgggtcc accaacagca cctcgttctc cgacaccggc ctgagcgcct ccaccgcgta
    19801 ctcgtacacg gtcaaggcga aggacgcggc cggcaacgtc tccgcggcct ccgcggcgct
    19861 cagcgtcacc acctccgccg gtggcaccac cgacaccacc gcgccgaccg ccccgaccaa
    19921 cctggcggcc accaccacct ccagcagcgc ttcgctgacc tggggcgcct ccaccgacaa
    19981 cgtcggcgtg accggttaca acgtgtaccg cggcggcacc ctgatcgggt ccaccaccag
    20041 cacctcgtac accgactcgg gcctgagcgc cgccaccgcg tactcgtaca cggtcaaggc
    20101 caaggacgcg gccggcaacc tctccgccgc cgcggccgtc accgccacca cccaggccgg
    20161 caccggcacc ggcagcgccg gctgcaccgc cacctacaag gtcagcagcg actggggcgc
    20221 cggcttcaac gccgacgtca ccgtgaccgc gggcaacacc gcgatcaagt cctggaaggt
    20281 cacctggacc tacgcgggca accagcaggt caccaacctg tggaacggca ccgtcagcca
    20341 gtccggccag tccgtgacgg tcaacaacgc cggctacaac ggcgcggtcg ccgcgaacgg
    20401 caccaccagc ttcggcttcg gcgccagcta ctccggcagc aacgccgtcc cgaccctgac
    20461 ctgcaccgcc accagctgac accaggcagc cggtagcacg cagcgggtag cggccgagcc
    20521 cgactgacgc gggacgaagc cgcagcgcac caccccgaag gcgccgccca cctgcagagt
    20581 ctgcaggtgg gcggttgccg ttcccgggcc gggcgatccg ggaagacctc aactccccag
    20641 ccggaaagcg gtgttgacca gggcgacgtg ggtgaacgcc tgcggggtgt tgcccagctg
    20701 gcgccgggcc agcgggtccc actgctcgct gagcagcccc aggtcgttgg ccaacgaggc
    20761 cgtccggacg aagagttcgc gcgcctcggc ccggcgcccg atcaccgcca gcgcgtccgc
    20821 cagccagaac gagcaggcca ggaacgcccc ttcggaaccg gtcaggccgt ccgccgcccc
    20881 cgtccggtag cggcgcacca gcccgccgtg gtccaggtcg cgccggacgg cctccacggt
    20941 gcgcaccacc cgttcgtcgt ccggcggcag gaagccggtg gtggcgacga acagcgtggc
    21001 ggcgtccaac tccgtcgccc cgtacgagcg gacgaacacc ttgcggcgcg ggtcgacggc
    21061 ccgctcgcac acctcggcgt gcaccgcgtc gcgcagcgcc cgccactgct ccagcggggc
    21121 gggcaggccg gtggcctcgg ccatccgcac cgcccggtcg gcggccaccc aggccatcac
    21181 cttggagtgg gtgaactgcc gccgcccgca ccgcacttcc cacaacccct cgtcgggctc
    21241 ccgccagcgg gcggccagcg agccgagcag ggtgcgcagc aggccccaga cctgccgctc
    21301 catcggcagg ccggcccgca gcgccaggtc gagggtgtcc accacctcgc cgtagacgtc
    21361 cagctggagc tgcccgacgg ccgcgttgcc gaaccggacc ggccgcgagc cgaggtgccc
    21421 gggcagccag tcggcctcgg tctccggcag gccgcgctcc ccggccaccc cgtacaccgc
    21481 ctgcacgtcg gacgggtcgc cggccaccgc ccgcagcagc catttgcgcc aggccgccgc
    21541 ctcctgccgg aagccgccgc gcagcagcgc cgagagcgtc atcgcggagt cgcgcagcca
    21601 gcagaaccgg tagtcccagt tgcgctcccc gcccggcacc tcgggcagcg agctggtcgg
    21661 cgcggcgacg atcccgccgg tcggctcgta cgccagcgcc ttcagggtca gcagcgagcg
    21721 cagcaccgcg tcccgccact cgccccggta gctcagctgc ccggcccagg cgcgccagtc
    21781 ggccagcgtc gcggccagca gcgcctccgg gtcggtgcgc ggggcggtgg ccaggtggga
    21841 gggctgccag gtcagcacga acgggacccg cacgccgggc agcgcggtga actcggagac
    21901 ggtggccagc ccggccccgg tgcccggtcc ggccgcggag ccgttcgcgc cgtaggtgtg
    21961 cacgccgggc gggacgcgca gccaggcggc gtccggcccg gcgacggcca cccggtggtg
    22021 ctcggtgcgg cgcacccacg ggtcgacccg gccgtggtgg aagcgcagcc gcagctcgcc
    22081 gcggaccggg acggcgccgc tgacgccctc gacgatccgc accagccgcg gggcgcggtc
    22141 ccggtgcggc atcaggtcgg tcaccttcac ctcgccgtcc ggggtgcgcc agcgggactc
    22201 cagcaccagg gtgtcgccga ggtagcggcg cccggtgcag tcgcccgcgc cgaccggggc
    22261 gatccgccag gcgccgtgct cgggggtgcc gagcagtgcg gcgaagcagc tgggggagtc
    22321 gaagcggggc aggcagagcc agtcgaccga gccgtccctg ccgaccaggg cggcggtctg
    22381 gagatcggag aggagcgcgt agtcctcgat gcgaccgccc atggggtgat tctgcgccga
    22441 tcgcgggcca ccgccacgcg ggacgcgcca cgccaccgtt cggacgccgt ggct
//
