LOCUS       NZ_CP113837            24696 bp    DNA     linear   CON 26-JAN-2024
DEFINITION  Kitasatospora sp. YST-16 chromosome, complete genome.
ACCESSION   NZ_CP113837
VERSION     NZ_CP113837.1
KEYWORDS    RefSeq.
SOURCE      Kitasatospora sp. YST-16
  ORGANISM  Kitasatospora sp. YST-16
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Kitasatospora.
REFERENCE   1  (bases 1 to 7659304)
  AUTHORS   Mo,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-NOV-2022) College of Life and Environment Science,
            Hunan University of Arts and Science, No. 3150 Dongting Avenue,
            Changde, Hunan 415000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 8.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 95.0x
            Sequencing Technology             :: Oxford Nanopore PromethION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/24/2024 04:37:03
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,903
            CDSs (total)                      :: 6,801
            Genes (coding)                    :: 6,649
            CDSs (with protein)               :: 6,649
            Genes (RNA)                       :: 102
            rRNAs                             :: 9, 9, 9 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 9, 9 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 152
            CDSs (without protein)            :: 152
            Pseudo Genes (ambiguous residues) :: 0 of 152
            Pseudo Genes (frameshifted)       :: 59 of 152
            Pseudo Genes (incomplete)         :: 103 of 152
            Pseudo Genes (internal stop)      :: 5 of 152
            Pseudo Genes (multiple problems)  :: 14 of 152
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:05:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6247962
            Orig. end                         :: 6272658
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP113837.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Mo Ping.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24696
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="18"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..24696
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24696
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14696](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14696
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    137..152
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.16"
                     /tool="antismash"
     gene            complement(350..1126)
                     /locus_tag="OU787_RS28160"
                     /old_locus_tag="OU787_28160"
     CDS             complement(350..1126)
                     /EC_number="4.2.1.17"
                     /NRPS_PKS="Domain: ECH (9-250). E-value: 4.7e-79. Score:
                     257.1. Matches aSDomain:
                     nrpspksdomains_OU787_RS28160_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014139237.1"
                     /locus_tag="OU787_RS28160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_28160"
                     /product="enoyl-CoA hydratase"
                     /protein_id="WP_030462501.1"
                     /transl_table=11
                     /translation="MTEYETILVDRKGRVGIITLNRPKALNALSTELMNEVVAAAKSFD
                     RDPEIGALVITGSAKAFAAGADIKEMQDNRFPEVYLDDWLGPWDELGRLRKPVIAAVAG
                     YALGGGCELAMLCDILIAADTAKFGQPEITLGVIPGIGGSQRLTRAVGKAKAMDLCLTG
                     RTMGAEEAERAGLVSRIVPADQLLPEALATAEKVAAMSLPAAVMMKESVNRAFETTLAE
                     GVRFERRLFHAAFATADQKEGMTAFAEKRPASFTNK"
     aSDomain        complement(377..1099)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_OU787_RS28160_ECH.1"
                     /evalue="4.70E-79"
                     /label="OU787_RS28160_ECH.1"
                     /locus_tag="OU787_RS28160"
                     /protein_end="250"
                     /protein_start="9"
                     /score="257.1"
                     /tool="antismash"
                     /translation="DRKGRVGIITLNRPKALNALSTELMNEVVAAAKSFDRDPEIGALV
                     ITGSAKAFAAGADIKEMQDNRFPEVYLDDWLGPWDELGRLRKPVIAAVAGYALGGGCEL
                     AMLCDILIAADTAKFGQPEITLGVIPGIGGSQRLTRAVGKAKAMDLCLTGRTMGAEEAE
                     RAGLVSRIVPADQLLPEALATAEKVAAMSLPAAVMMKESVNRAFETTLAEGVRFERRLF
                     HAAFATADQKEGMTAFAEK"
     gene            complement(1235..2290)
                     /locus_tag="OU787_RS28165"
                     /old_locus_tag="OU787_28165"
     CDS             complement(1235..2290)
                     /EC_number="3.1.2.-"
                     /NRPS_PKS="Domain: ECH (17-197). E-value: 4.1e-28. Score:
                     90.3. Matches aSDomain: nrpspksdomains_OU787_RS28165_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031412.1"
                     /locus_tag="OU787_RS28165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_28165"
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="WP_268661024.1"
                     /transl_table=11
                     /translation="MGTPQGGQDVLIGRAGPLGRITLNRPRALNSLTRPMLETVRAALD
                     AWAADDTVTAVLLDGAGERGLCAGADIRAIHDDAKHGGAGGRAFFRVEYPLNELVSRYP
                     KPYVALMDGITMGGGVGLAGHAGIRVVTERSAVAMPETRIGLVPDVGGSRLLALAPGEL
                     GTHVALTAATMTAGDALHCGFADHYLPSTDLPALTDRLAAGDTPAKAVAELAAPAPPSA
                     LAEQHEWIDHCYAADSVEEILERLHATGLPAAADAAAQLRAKSPTMLKVTLAALRRART
                     LPSLAATLDQEYRISCAALAHHDLVEGIRAQVVDKDRDPHWSPATLAEVTPADVARFFA
                     APESGDLHLAG"
     aSDomain        complement(1700..2239)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_OU787_RS28165_ECH.1"
                     /evalue="4.10E-28"
                     /label="OU787_RS28165_ECH.1"
                     /locus_tag="OU787_RS28165"
                     /protein_end="197"
                     /protein_start="17"
                     /score="90.3"
                     /tool="antismash"
                     /translation="LGRITLNRPRALNSLTRPMLETVRAALDAWAADDTVTAVLLDGAG
                     ERGLCAGADIRAIHDDAKHGGAGGRAFFRVEYPLNELVSRYPKPYVALMDGITMGGGVG
                     LAGHAGIRVVTERSAVAMPETRIGLVPDVGGSRLLALAPGELGTHVALTAATMTAGDAL
                     HCGFADHYLPSTDLPAL"
     gene            complement(2419..2601)
                     /locus_tag="OU787_RS28170"
                     /old_locus_tag="OU787_28170"
     CDS             complement(2419..2601)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="OU787_RS28170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="OU787_28170"
                     /product="hypothetical protein"
                     /protein_id="WP_030462499.1"
                     /transl_table=11
                     /translation="MMKLRTLVCGAALAAANLLLPVPQAQAAPLTPHPVMLCGFAPRPA
                     VPAAPVLLATPLRPC"
     misc_feature    2699..2719
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.43"
                     /tool="antismash"
     gene            complement(2849..4069)
                     /gene="fahA"
                     /locus_tag="OU787_RS28175"
                     /old_locus_tag="OU787_28175"
     CDS             complement(2849..4069)
                     /EC_number="3.7.1.2"
                     /GO_function="GO:0004334 - fumarylacetoacetase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006559 - L-phenylalanine catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fahA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014139240.1"
                     /locus_tag="OU787_RS28175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_28175"
                     /product="fumarylacetoacetase"
                     /protein_id="WP_030462498.1"
                     /transl_table=11
                     /translation="MSTTATWLDLPADSPYGVHNLPYGVFTAADRPGRRRIGVRIGELV
                     LDAGAAARAVGAPSALLDAESLNPLMASGRSTWRAVRAALTSWLTDEAHRDAVGPCLLP
                     LADVRLHLPFEVADYVDFYASEHHATNLGKIFRPGQEPLTPNWKHLPIGYHGRAGTVVV
                     SGTPVARPHGQRKAPADAAPSFGPSLRLDIEAEVAFVVGTPSELGRPVALDGFAEHVFG
                     VCLLNDWSARDLQAWEYVPLGPFLGKSFATSVAPWVVPLEALEHARVEPPARDVEPLPY
                     LDDRKAEPWGLDLAMEVSLNGHPVSRPPFAGMYWTAAQQLAHLTVNGANLRTGDLYGSG
                     TVSGPEPEQRGSLIELSWNGTRPLELPDGTSRTFLEDGDEVSITATAPGPGGLRVGFGE
                     VTGRITG"
     gene            complement(4066..4878)
                     /locus_tag="OU787_RS28180"
                     /old_locus_tag="OU787_28180"
     CDS             complement(4066..4878)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009080542.1"
                     /locus_tag="OU787_RS28180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_28180"
                     /product="hypothetical protein"
                     /protein_id="WP_232795119.1"
                     /transl_table=11
                     /translation="MDLGEAMNVPELYRGLFDDAAVFPPGDLPLAEAVPAHRAHRAARY
                     AAAVGPLLAPVDLLAELRELEPEFEVGLVVGPGRLAEALKAADGLRVATVEYAPGPDVR
                     AAVAELDALLPEGVGAAVELPRSERLEDGLDALAGTRYRAKYRTGGLGYAAFPSVTELA
                     GFLRGCAERALPYKCTAGLHHAVRHTDLGTGYEHHGFLNLLLAAGSPSREQAVELLAER
                     DGARLATAVESLTERQILDIRASFTSFGTCSITEPLEDLARLGLLETP"
     gene            complement(4857..6044)
                     /locus_tag="OU787_RS28185"
                     /old_locus_tag="OU787_28185"
     CDS             complement(4857..6044)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014139242.1"
                     /locus_tag="OU787_RS28185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_28185"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_268661025.1"
                     /transl_table=11
                     /translation="MAYYRQLGSVPPKRHTQHRTPEGGLYYEELMGEEGFSSDSSLLYH
                     RYIPSAVTAAAVWELPSQATTANLPLLPRHLKLHELFPGEEWKSADAVTGRRLVLGNAD
                     VRISYVAAGAPSELYRNGLGDECVYVESGTAVLETVFGTIAVGQGDYVLIPRATTHRWV
                     PTGDAPLRAYCIEANSHITPARRYLSKFGQLLEHAPFCERDLRGPQGPLLVEGGEVDVL
                     VKHRGPGGVVGTRYTVPNHPFDVVGWDGCLYPYAFNIADYEPITGRVHQPPPAHQVFEG
                     NNFVICNFVPRKVDYHPLSIPVPYYHANVDSDEVMFYCGGNYEARKGSGIGQGSISLHP
                     GGHTHGPQPGAYERSIGVEFFDELAVMVDTFRPLELGEAATASEDPNYAWTWARR"
     misc_feature    6068..6081
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.85"
                     /tool="antismash"
     gene            complement(6079..7290)
                     /gene="hppD"
                     /locus_tag="OU787_RS28190"
                     /old_locus_tag="OU787_28190"
     CDS             complement(6079..7290)
                     /EC_number="1.13.11.27"
                     /GO_function="GO:0003868 - 4-hydroxyphenylpyruvate
                     dioxygenase activity [Evidence IEA]"
                     /GO_process="GO:0006559 - L-phenylalanine catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hppD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014139243.1"
                     /locus_tag="OU787_RS28190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_28190"
                     /product="4-hydroxyphenylpyruvate dioxygenase"
                     /protein_id="WP_030462495.1"
                     /transl_table=11
                     /translation="MTADAAVELTPEELQAGLTAEQLRTLVGLVEYDASTDPFPVTAQD
                     AVVFVVGNATQTAQFYQAVFGMELVAYSGPETGRRDRKSFVLRSGSCRFVIEGGVTPDS
                     PLLDHHRRHGDGVVDLAMEVPDVDKCIAHARAQGATVLEEPNDVSDEHGTVRRAAIAAY
                     GETRHTLVDRSRYTGPYLPGYVARESTVVRPEGAPKRLFQALDHAVGNVELGKMDEWVS
                     FYNRVMGFVNMAEFVGDDIATDYSALMSKVVASGNHRVKFPLNEPAIAKKKSQIDEYLE
                     FYTGPGCQHMALATNDILTTVDVLRSRGVEFLSTPDSYYEDPELRERIGHVRAPIEELQ
                     SRGILVDRDEDGYLLQIFTKPIGDRPTVFYEFIERHGSLGFGKGNFKALFEAIEREQDR
                     RGNL"
     misc_feature    7370..7384
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.13"
                     /tool="antismash"
     misc_feature    complement(7370..7388)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.34"
                     /tool="antismash"
     gene            complement(7424..8728)
                     /locus_tag="OU787_RS28195"
                     /old_locus_tag="OU787_28195"
     CDS             complement(7424..8728)
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019436034.1"
                     /locus_tag="OU787_RS28195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_28195"
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="WP_268661026.1"
                     /transl_table=11
                     /translation="MHFTDRADAGRRLAAALLSEAPELRGAVVVALPRGGAPVAAEVAA
                     ALGAELDVCVVRKVGVPGQPEVAMGAVGEDGARVVNQQVVDAAGVPPEAFAAAEARERS
                     ELARRAALYRGGRAPVPLAGRTVLVVDDGVATGASARAACRIVRARGAARVVLAVPVAP
                     PGWARQLGDAADGYLAVDTPDGFAAVGAFYRDFRQTTDAEVLAALDRAGPPKAAGPAGQ
                     ELRLGTGAADLAVPEHPRGVVLFAHGSGSGRNSPRNRAVAAHLHRERLATVLFDLLTPG
                     EADERWKVFDPGLLGGRLAGATREALRHPALAGLPYGWFGASTGAAAALWAAAEPDSAP
                     AAIVARGGRPDLAEARLPLVTVPTLLIVGGADQEVLEWNRQARAELGGESALQVVPGAG
                     HLFEEPGALEAVAALAAGWFVRHFPPGRGGDRVEH"
     misc_feature    complement(8778..8787)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 15.81"
                     /tool="antismash"
     gene            8901..9317
                     /locus_tag="OU787_RS28200"
                     /old_locus_tag="OU787_28200"
     CDS             8901..9317
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014139245.1"
                     /locus_tag="OU787_RS28200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_28200"
                     /product="SPW repeat protein"
                     /protein_id="WP_232795118.1"
                     /transl_table=11
                     /translation="MEHHPDILALREHAERVTSTTAGQGTEALAVCAGLFLAISPWVVG
                     FSGFTGLAISNLVLGIAYAVLMAGYGSAFGRTHARAWACVAIGAWTVIAPWAVNGGAHV
                     RRTILTNVITGGVMTCLALAAVGMVFAGMTARRR"
     misc_feature    9681..9694
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.13"
                     /tool="antismash"
     gene            9752..9907
                     /gene="lanA"
                     /locus_tag="OU787_RS28205"
                     /old_locus_tag="OU787_28205"
     CDS             9752..9907
                     /codon_start=1
                     /gene="lanA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) strep_PEQAXS"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978597.1"
                     /locus_tag="OU787_RS28205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_28205"
                     /product="SCO0268 family class II lanthipeptide"
                     /protein_id="WP_063765064.1"
                     /sec_met_domain="strep_PEQAXS (E-value: 1.1e-26, bitscore:
                     91.2, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTETTVQSDTTDFDLDLRIADVAEQTEEFGRGTYTSPSSYAIGT
                     RCPVCC"
     gene            10001..13096
                     /locus_tag="OU787_RS28210"
                     /old_locus_tag="OU787_28210"
     CDS             10001..13096
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014179519.1"
                     /locus_tag="OU787_RS28210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_28210"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_268661027.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 3.1e-165,
                     bitscore: 549.6, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 1.5e-17,
                     bitscore: 62.7, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 4.1e-33, bitscore:
                     113.9, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAEPDPFDVREPVLVRTAGTPRTGTETRIDPADPVPGARRLAAD
                     PLLRQAVEVASGSLALSLQRLGEPGGAAALGRKRTASAARTLTRYARRSGGRPTPFGLF
                     AGVGRARFGAAADVPPPGPGQVRVRLDGGWLHRRVLDWLAVPEVRRRVDVVLDDLTVLR
                     DGRLLRHTGEREVSVRDNPLVTRVREAAARPVGYADLLADLTARFPAVAPERIDGLLAG
                     LVQHGFLLTSLTPHRVDDALLDRIDTALDGAVPAAAEGLRAVRAAATAHERDRPGEGLA
                     SWRHLLEQVRALDPDDRAGERPPVQVDLRTGADLVLPAAVGEEVRRYAAAIWAITPEWT
                     TLDHLRDYRDRFVEHYGTASAVPLADLADPHRGLGLPPEYGGAAPAHSRSGPGDDADRP
                     RRNAVAELVQQAVLAGTDLVLDDADLARLADAAGHTPGSSRPPRTLELCFQLLADSAAA
                     LDRGEFLLLGSPHTGSWTAGATAGRFADLTGLTADLAALAAGPADDGALPVQVELAPRD
                     PRSLNIVQVPPLLPHRLPIGVAADRGDPHCLDWRTLLVAAGEDGLRLLHPDTGRPVVPV
                     FPHMLALDAQAPPVARFLADLAAARPRVWSGWDWAGLDTLPYLPAVRHGRVLAAPRRWL
                     PGRRLRDAARTAGPAAWTEGLRTWRERYRVPDRLQIASNDRMFPIDLREDWDTDLLRAE
                     LTAPEPRFQLFQDLTADGAGLGWNHGRSTEIVVPLLRAPRPAPAGTRPPLARSAVRTAP
                     TRIHLPGEDWLFAKLYAEPGTHDTLLADHLPALLADVEPHVDRWFFLRYRDPEPHLRLR
                     LHGDPAALAGHVLPALARHVRRLVGTGALRTTALDTYRPETDRYLGPGAQEAAERLFQT
                     DSRSALLQLRARRAGAAAVPDEVLAATGHAVLLDSLGDWDWCAWVVHLFEKGADHRAHQ
                     RHRALADRLIRPDDTARHAAEHLGIPDLAPLWTDTPAPRDFGRLLLAAPEADRDEALMS
                     LLHMRHNRLFGIDPAAEARGYAVLRGAARALIGRKSHAGEGK"
     aSDomain        10460..10708
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_OU787_RS28210_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="6.10E-20"
                     /identifier="RREFam001.1"
                     /label="OU787_RS28210"
                     /locus_tag="OU787_RS28210"
                     /protein_end="236"
                     /protein_start="153"
                     /score="62.7"
                     /tool="antismash"
                     /translation="VVLDDLTVLRDGRLLRHTGEREVSVRDNPLVTRVREAAARPVGYA
                     DLLADLTARFPAVAPERIDGLLAGLVQHGFLLTSLTPH"
     gene            13347..14696
                     /locus_tag="OU787_RS28215"
                     /old_locus_tag="OU787_28215"
     CDS             13347..14696
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978595.1"
                     /locus_tag="OU787_RS28215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_28215"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_268661028.1"
                     /sec_met_domain="LANC_like (E-value: 2.7e-52, bitscore:
                     176.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTVQATAVSAERARLRAAAGQLSDLILDRLADPAATVAATRIP
                     AEAADDGVAENVWAELTLGSGSPGLSLAFSGGARPGTERAARAHGYLAVATRAAGAGDT
                     VPSGIFKGPGALAFAVLAAHRATGGYTGALHRLDAYQRQLVRTALPAVPDGPLATIGHY
                     EVVRGMTGVGRYLLARAESCGEELELVLGYLIELARGTTAHRGARVPRWWALDAPRIGS
                     EHLLPDGHLNLGLSHGVAGPLMLLALAWRDGVRLPGHREALESTADLLVRWAVRDEHGS
                     YWPGYLGLDAYLAGPDAYREPAGWPSWCYGAPGVSRALQTAGAALGRPEWTAVARDSVE
                     RLLRVPLDDWGVTDHALCHGWAGALHQLGRLNEHFGEERIERRRDETAARLLAGHDPDA
                     PFGLRFTMTRRPFASDVSGYLDGAAGVALALDSYAAGGTPHDWDMPLLLS"
     gene            complement(14724..16163)
                     /locus_tag="OU787_RS28220"
                     /old_locus_tag="OU787_28220"
     CDS             complement(14724..16163)
                     /EC_number="4.2.1.2"
                     /GO_function="GO:0004333 - fumarate hydratase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /GO_process="GO:0006106 - fumarate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006108 - malate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063: argininosuccinate lyase/adenylosuccinate lyase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014139246.1"
                     /locus_tag="OU787_RS28220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_28220"
                     /product="class II fumarate hydratase"
                     /protein_id="WP_268661029.1"
                     /transl_table=11
                     /translation="MADGQQDRQHGQQDGQQWRTEHDSMGEVRVPAAAKWRAQTQRAVE
                     NFPVSGQRLERAHIAALARIKAAAATVNAGLGVLDEETAAAIRSAAEEVAEGRWDDQFP
                     VDVFQTGSGTSSNMNANEVIATLAAERLGRPVHPNDQVNASQSSNDVFPSSIHVAATGA
                     VLHELVPALEHLARALEAKSAEFAGVVKSGRTHLMDATPVTLGQEFSGYAAQVRYGVER
                     LRATLPRVAELPLGGTAVGTGINTPPGFSAAVIAEVARATGLPLTEARDHFEAQGARDG
                     LVELSGQLRTIAAGFTKIANDLRWMGSGPRTGLAEINLPDLQPGSSIMPGKVNPVLPEV
                     VLMVAAQVIGNDTTVTVAGASGNFELNVMLPVIARNVLESVRLLTTSARLLADRTVDGI
                     TANAERTREYAESSPSVVTPLNRYLGYEEAAKVAKQSLAERRTIRQVVLDRGYVERGLL
                     TEAQLDEALDVLRMTRPQDAD"
     misc_feature    16299..16312
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.31"
                     /tool="antismash"
     gene            16337..17524
                     /locus_tag="OU787_RS28225"
                     /old_locus_tag="OU787_28225"
     CDS             16337..17524
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018558937.1"
                     /locus_tag="OU787_RS28225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_28225"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_030463568.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.6e-29, bitscore:
                     101.4, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 2.6e-24, bitscore:
                     83.9, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 6e-30, bitscore:
                     103.1, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATAAPAGRPDPLDLLGVDELLTEDERLVRDSVRAFTDRHVRPHL
                     ADWYERGTFPVRELAPELGKLGVLGMHLEGYGCTGSTATEYGVACMELEAADSGLRSFV
                     SVQGSLAMRSIHAYGSEEQKRHWLPELAAGRAVGCFGLTEPEAGSDPASMRTRARRDGG
                     DWILDGAKMWITNGSVSDVAVVWAGTEDGVRGFLVPRGTPGLTARDIPGKLSLRASVTS
                     ELAFDGVRLPADAQLPQARGLRAPLASLGEARYGILWGTVGAARDCYRAAVDYARDRVQ
                     FGRPIGGFQLTQAKLVDMALELEKAYLVAVRIGRLKDAGRAQAAHISFGKLNNVRTALE
                     IARTARTILGANGITTAYPVLRHANNLESVLTYEGTSEVHTLVLGEAITGESAYR"
     gene            17728..18195
                     /locus_tag="OU787_RS28230"
                     /old_locus_tag="OU787_28230"
     CDS             17728..18195
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="OU787_RS28230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="OU787_28230"
                     /product="hypothetical protein"
                     /protein_id="WP_268661030.1"
                     /transl_table=11
                     /translation="MGGERSRRAAATVVVGGAAAAMLLVMVAPAAIQRVQDRLDQTVRY
                     PNGSAAKADRTEVPRWLPDSATGIAFLASGDGGERLIRATVPDRALPTACTTTGHTLDD
                     PHLRAHWFPTDTPRRATAHCGQYDVALVGDQLYGWRGAPAAAGARTAGPTG"
     gene            18285..19556
                     /locus_tag="OU787_RS28235"
                     /old_locus_tag="OU787_28235"
     CDS             18285..19556
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014139249.1"
                     /locus_tag="OU787_RS28235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_28235"
                     /product="multidrug effflux MFS transporter"
                     /protein_id="WP_030463570.1"
                     /transl_table=11
                     /translation="MPGPTVDPDGDQTAPDVPLRPAQEAAQAPQRAPFATATVITLGCL
                     VALGPFTTDLYLPALPDLTADLGSTAAAAQLTLTGSLLGMVLGQLLFGPLSDRLGRRRP
                     MLAGLAAFTAASLLCAFADSMPLLVAGRVVQGAAGSAALVIARATVRDRLEGTAMIRFL
                     ATMGLISGLAPIVAPLAGAQLLHVTDWRGTFVALALLGAVLTVACGFGIGETLPPERRH
                     GGGLGTTVRAIGGLLRDRVFLGYLLVSTFAFGALFAYVGGSSVVLQEVYRITPQTYSLV
                     FAVNSVSLLAVTQFNGRFLVQRYSERTLLVCGLGAAALAGAAVVLCTTVWDTGLAGVWP
                     ALTVLMGAMGVILPNANGQALTMAPHAAGSASALLGTGTYLCGAVVAPLSSLGGHPSAT
                     VLGAVVLGCALLALGSFLPLCRGR"
     gene            complement(19641..21683)
                     /locus_tag="OU787_RS28240"
                     /old_locus_tag="OU787_28240"
     CDS             complement(19641..21683)
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014139252.1"
                     /locus_tag="OU787_RS28240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_28240"
                     /product="glycosyl hydrolase family 18 protein"
                     /protein_id="WP_268661031.1"
                     /transl_table=11
                     /translation="MRLHRPLQALLATGAMAAASLGLISAPAQAATPLPQHVFAPYFEA
                     WTGDNPATLAAQSGAKNLTMAFLQAATKGSCTALWNGDTSMPVSNSVFGADIATIRANG
                     GDVIPSFGGYTADNTGTEIADSCTDVNQIAAAFENVITTYDVSRIDLDIEDNSLTNTAG
                     IDRRNKAIKIVEDWAAANGRNIQFSYTLPTTTSGLASSGLAVLKNAVSNNARIDVVNMM
                     TFDYYDNQPHDMAADTQTSAQGLYNQLAKLYPTKTSTQLWNSIGIIEMIGIDDFGAAET
                     FTVANANTVYDWAVSKGINTLSFWALQRDNGGCAGTAGSDSCSGIAQGTWDFSHIFSKF
                     TSSSVPANDFSVSLSPATGSVTAGASTSATVSTAVTSGSAQSVNLSVTGAPAGVTASLS
                     ASTVTAGGSATLNVATTAGVANGSYPLTVTGTGASGTHSATYTLTVTGGTTASDFSVAL
                     APAAGSVQAGSAASSTVNTAVTSGTAATVNLTVSGAPAGVTASLSASSVTAGGSATLNV
                     ATTAAAAPGTYTLTVTGTGAGKTHTATYALTVTGTTPTGGLVNGDLEGGLAPWTCQSGG
                     GVVSTPVHGGSKALQAAPTAGTTGECDQTVTLAPNHAYTLTAWVQGPYSYVGVSGGATA
                     STWANGSSWTKVSVPFTTGANGTVTVYLHGWYGQGSVYGDDFSIA"
     misc_feature    21854..21869
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 23.25"
                     /tool="antismash"
     misc_feature    21880..21898
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.9"
                     /tool="antismash"
     gene            complement(22014..22940)
                     /locus_tag="OU787_RS28245"
                     /old_locus_tag="OU787_28245"
     CDS             complement(22014..22940)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014139253.1"
                     /locus_tag="OU787_RS28245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_28245"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_268661032.1"
                     /transl_table=11
                     /translation="MTTRPVRTALAVLLLAGAAACSSSGGGDPLAAKSSGPAASAPAGG
                     SGKTVVVGSANFPENVLLASIYSQALKAKGVPVEEKFNIGSRELLYGQLQSGALTVLPE
                     YNGALLGYLDAKSTATGKDAVNTELKAKLPAGLAILDSSAAEDKDSLTVTQETADKLGV
                     KSIADLAGKAQDLVVGGPPEFKSRREQQFKDAYGLTFKEWKPTGDTTANALKDGTVQVG
                     NVFTTDPKLVQLKLVSLADPKNVFSAQNVTPLVNQAGLDATGTAALNAVSAKLDTAGLT
                     ALMKRVAVDKEDPAAVAAAWLKSSGLN"
     gene            complement(22937..23719)
                     /locus_tag="OU787_RS28250"
                     /old_locus_tag="OU787_28250"
     CDS             complement(22937..23719)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014139254.1"
                     /locus_tag="OU787_RS28250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_28250"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_232795185.1"
                     /transl_table=11
                     /translation="MNWLGWLHDFFADPAHRSGPDSIVHRVLEHLAFSAEALGLAALVA
                     LPLGLLIGYSGRGLFLVTALAGVARALPTLGLVTLAVLLAGVGETAVLLPLTALAAPPM
                     LVAAAEGVRGTDPDVRDAARGIGLTHPQTLLRVCVPAAAPTLLAGVRTASVQVIATATV
                     AAYVGLGGLGRYVIDGLATRNYPTTVGGALLVVLLAVAVQLLFALFVRLASPPGARPVR
                     AVRRVRAAGSAGGGGASAGGSAPDDDPAGSPALVKESP"
     gene            complement(23716..24378)
                     /locus_tag="OU787_RS28255"
                     /old_locus_tag="OU787_28255"
     CDS             complement(23716..24378)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014139255.1"
                     /locus_tag="OU787_RS28255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_28255"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_030463574.1"
                     /transl_table=11
                     /translation="MLDGEPLIRWRWLGDHLGYLGDLTADHAVIALVPVLLALLLAVPL
                     GLACARFPRLYQPLAAVFNVVYALPSLAVFVVLIPYTGLATRETVMVPLTCYALAVLLP
                     TAVDGLRAVPEPVRQAATAMGYGPWRRLAAVELPASVPYLIGGLRVAAVSSISLAAVGA
                     LVGRGGLGYLFVDGFQRTFPTPILAGIVLVALLALAADLLLLAARRVLAPWSRGVAR"
ORIGIN
        1 cctgatccgc tgccgcggcc tcggcccccg ctcccccctg accgccgcgg ccaccatccg
       61 cgccctcacc gccctcggcg gcccggacgc ccgcaccgaa ctggaacgcc tcgccggcac
      121 gctcacctac aagccgaccc tgaaggcgat caccaccgcc ctcaccaccc gcaacagctg
      181 accccccacc agaaccccgc aggagccccc accggcaccc ctgcggggtt ttcccctgcg
      241 ggggtttccc ctgcgggggt ttcccctgcg ggggtttccc ctgcgggggt ttcccctgcg
      301 ggggtttccc ctgcgggggt ttcccctgcg gggctttccc ctgcgggggt tacttgttgg
      361 tgaaggaggc cgggcgcttc tcggcgaagg cggtcatgcc ctccttctgg tcggcggtgg
      421 cgaaggcggc gtggaagagg cggcgttcga agcggacgcc ctcggcgagg gtggtttcga
      481 aggcgcggtt gacggattcc ttcatcatga cggcggcggg gagggacatg gcggcgacct
      541 tctcggcggt ggcgagggcc tcggggagga gttggtcggc ggggacgatc cgggagacca
      601 ggccggcccg ttcggcctcc tcggcgccca tggtgcggcc ggtcaggcac aggtccatgg
      661 ccttggcctt gccgacggcg cgggtcaggc gctgggagcc gccgatgccg gggatgacgc
      721 cgagggtgat ctcgggctgg ccgaacttcg cggtgtcggc ggcgatcagg atgtcgcaga
      781 gcatcgccaa ctcgcagccg ccgccgagcg cgtagcccgc gaccgcggcg atgaccggct
      841 tgcgcaggcg gccgagctcg tcccaggggc cgagccagtc gtcgaggtag acctcgggga
      901 agcggttgtc ctgcatctcc ttgatgtcgg cgccggcggc gaacgccttg gcggagccgg
      961 tgatcaccag ggcgccgatc tccgggtcgc ggtcgaagga cttggcggcc gccaccacct
     1021 cgttcatgag ttcggtgctg agcgcgttga gcgccttggg ccggttgagg gtgatgatgc
     1081 cgacccggcc cttgcggtcg accaggatcg tctcgtactc ggtcatcgcc gtttcttcct
     1141 ctccacgctg agcggaacct ctgccgctgg atacgatctc cgaacgccgc gccggatgcc
     1201 agtctcgaca ggcgagacga tggtcacccc ggtgtcatcc ggccaggtgc aggtcgccgc
     1261 tctcgggggc ggcgaagaag cgggccacgt cggcgggggt gacctcggcc agggtggcgg
     1321 gggaccagtg cgggtcgcgg tccttgtcga cgacctgggc gcggatgccc tcgaccaggt
     1381 cgtggtgggc cagggcggcg caggagatcc ggtactcctg gtcgagggtg gcggccagcg
     1441 agggcagggt gcgggcccgg cgcagcgcgg ccagggtcac cttgagcatg gtgggggact
     1501 tggcgcgcag ctgggcggcg gcgtccgcgg cggcgggcag gccggtggcg tgcaggcgtt
     1561 ccaggatctc ctcgacgctg tcggcggcgt agcagtggtc gatccactcg tgctgctcgg
     1621 cgagcgcgga gggcggggcg ggggcggcga gttcggcgac ggccttggcg ggggtgtcgc
     1681 cggcggcgag acggtcggtg agggcgggca ggtcggtgga gggcaggtag tggtcggcga
     1741 agccgcagtg cagggcgtcg ccggcggtca tggtggcggc ggtgagggcg acgtgggtgc
     1801 cgagttcgcc gggggcgagg gcgagcagcc ggctgccgcc gacgtcgggg accaggccga
     1861 tccgggtctc gggcatggcg acggcggagc gctcggtgac gacccggatg ccggcgtgtc
     1921 cggcgaggcc gacgccgccg cccatggtga tgccgtccat cagggcgacg tacggcttgg
     1981 ggtagcggga gacgagttcg ttgagcgggt actcgacccg gaagaaggcc cggccgccgg
     2041 cgccgccgtg cttggcgtcg tcgtggatgg cccggatgtc ggcgcccgcg cacaggccgc
     2101 gttcgcccgc gccgtcgagc aggacggccg tcacggtgtc gtcggcggcc caggcgtcca
     2161 gggcggcgcg gacggtctcc agcatcgggc gggtgaggga gttgagggcg cgcggccggt
     2221 tgagggtgat ccggccgagc gggccggccc gcccgatcag cacgtcctgc ccgccctgtg
     2281 gggttcccat cgccaccgct cccatcgctc ccaccgctcc cgtccgtccg gaaagtacga
     2341 agatccttcg gtgcaccgta ccgggcccgc cgggcaggtc ggcgggcccg ggtgcggcgg
     2401 tggcggggac ggggccggtc agcaggggcg cagcggggtg gcgagcagca cgggggcggc
     2461 ggggacggcg gggcgcgggg cgaagccgca gagcatcacg gggtgcgggg tcagcggggc
     2521 ggcctgggcc tgggggacgg gcagcagcag gttggcggcg gcgagcgcgg ctccgcagac
     2581 cagggtgcgc agcttcatca tcgggggttc ctccggggaa gagagttgtc cgcgaacggt
     2641 cgcggtccgc tccttcggcg ccgggcgtgg gaggcccggc tcgggggcgg ccgcggggtt
     2701 ttcgtcgggt caacttctag tggcggaggg gtttgcggcc ccggaacctc acccgttcgg
     2761 cggcgtgctg cggacgcgcc gttgacgctt ccgcagcacg ccggacgacc ggcctgctgt
     2821 caggtcggcc gatcgcccgg tcggcgggtc agccggtgat ccttccggtg acctcgccga
     2881 acccgacccg caggcccccc ggcccggggg cggtggcggt gatggacacc tcgtcgccgt
     2941 cctccaggaa ggtgcggctg gtgccgtcgg gcagttcgag cggccgggtg ccgttccagg
     3001 acagctcgat cagcgagccg cgctgttccg gctcggggcc ggagaccgtg ccggagccgt
     3061 acaggtcgcc ggtgcgcagg ttggcgccgt tgacggtgag gtgggcgagc tgctgggcgg
     3121 cggtccagta catgccggcg aacggcggcc gggagaccgg gtggccgttc agcgagacct
     3181 ccatcgccag gtccaggccc cagggctcgg ccttgcggtc gtccaggtag ggcagcggtt
     3241 ccacgtcgcg ggccgggggc tcgacccggg cgtgctccag cgcctccagc ggcaccaccc
     3301 agggggcgac cgaggtggcg aaggacttgc cgaggaacgg gccgagcggc acgtactccc
     3361 aggcctggag gtcgcgcgcg gaccagtcgt tgagcaggca gacgccgaac acgtgctcgg
     3421 cgaagccgtc cagcgcgacc ggccggccca gttcgctggg cgtgccgacc acgaaggcga
     3481 cctcggcctc gatgtccagg cgcagggacg ggccgaagct cggcgcggcg tcggcggggg
     3541 ccttgcgctg gccgtgcggg cgggccaccg gggtgccgga gaccaccacg gtgccggccc
     3601 ggccgtggta gccgatcggc aggtgcttcc agttcggggt cagcggttcc tggcccgggc
     3661 ggaagatctt cccgaggttg gtggcgtggt gctcggaggc gtagaagtcg acgtagtcgg
     3721 cgacctcgaa cggcaggtgc agccggacgt ccgccagcgg cagcaggcag ggcccgacgg
     3781 cgtcccggtg cgcctcgtcg gtgagccagg aggtgagcgc cgcgcgcacc gcccgccagg
     3841 tcgaacggcc ggacgccatc agcgggttga ggctctccgc gtccagcagc gcggacggcg
     3901 cgccgaccgc ccgggcggcc gccccggcgt ccagcaccag ctccccgatc cggacgccga
     3961 tccgccgccg gccgggccgg tcggcggcgg tgaacacgcc gtaggggagg ttgtggacgc
     4021 cgtacgggga gtcggcgggc aggtcgagcc aggtggcggt ggtgctcaag gggtctccag
     4081 gaggccgagt cgggcgaggt cttccagcgg ctcggtgatg ctacaggtgc cgaacgaggt
     4141 gaaagaggcg cggatgtcga ggatctgacg ctccgtcagc gactcgacgg cggtggccag
     4201 tcgggcccca tcccgttcgg cgagcagctc gacggcctgc tcgcggctcg gactcccggc
     4261 cgccagaagg aggttgagga agccgtggtg ctcgtagccg gtgcccaggt cggtgtgccg
     4321 caccgcgtgg tgcagccccg ccgtgcactt gtacggcagg gcgcgctcgg cgcagccccg
     4381 caggaagccg gccagctcgg tcaccgacgg gaaggcggcg taaccgaggc cgccggtacg
     4441 gtacttggcg cggtagcggg tgccggccag ggcgtccagg ccgtcctcca gccgctccga
     4501 gcggggcagt tcgacggccg ccccgacgcc ctcgggcagc agcgcgtcca gttcggcgac
     4561 cgcggcccgg acgtccgggc ccggcgcgta ctcgacggtg gcgacccgca ggccgtccgc
     4621 ggccttcagc gcctcggcca gccggcccgg gccgaccacc aggccgacct cgaactccgg
     4681 ctccagctcc cgcagttcgg ccagcaggtc gacgggggcg agcagcgggc cgaccgccgc
     4741 cgcgtaccgg gcggcgcggt gcgcccggtg cgcggggacg gcctcggcca gcggcaggtc
     4801 gccgggcggg aagaccgccg cgtcgtcgaa cagcccccgg tacagctcgg gtacgttcat
     4861 cgcctcgccc aggtccacgc gtagttcggg tcctcgctgg cggtggcggc ctcgccgagc
     4921 tccagcgggc ggaaggtgtc caccatcacc gccagctcgt cgaagaactc cacgccgatc
     4981 gagcgctcgt aggcgcccgg ctgcggcccg tgggtgtggc cgccggggtg cagcgagatc
     5041 gacccctgtc cgatgccgga gcccttgcgg gcctcgtagt tgccgccgca gtagaacatc
     5101 acctcgtcgc tgtccacgtt cgcgtggtag tacggcacgg ggatcgacag cgggtggtag
     5161 tccaccttgc gcggcacgaa gttgcagatc acgaagttgt tgccctcgaa cacctggtgg
     5221 gccggcggcg gctggtgcac ccgcccggtg atcggctcgt agtccgcgat gttgaacgcg
     5281 tacgggtaca ggcagccgtc ccagcccacc acgtcgaacg ggtggttcgg caccgtgtag
     5341 cgggtgccga ccacgccgcc cgggccgcgg tgcttgacca gcacgtccac ctcgccgccc
     5401 tcgaccagca gcgggccctg cggcccgcgc aggtcccgtt cgcagaacgg ggcgtgctcc
     5461 agcagctggc cgaacttcga caggtagcgg cgggccgggg tgatgtggct gttcgcctcg
     5521 atgcagtacg cgcgcagcgg ggcgtccccg gtcggcaccc agcggtgggt ggtggcccgc
     5581 gggatcagca cgtagtcgcc ctgcccgacc gcgatcgtcc cgaacaccgt ctccagcacg
     5641 gccgttccgg actccacgta cacgcactcg tcgccgagcc cgttgcggta cagctcgctg
     5701 ggcgcgcccg ccgcgacgta ggagatccgg acgtccgcgt tgccgaggac gagccggcgg
     5761 ccggtgacgg cgtccgccga cttccactcc tcgccgggga acagctcgtg cagcttgagg
     5821 tggcggggga gcagcgggag gttggcggtg gtcgcttggc tcggcagctc ccacaccgcg
     5881 gcggccgtca ccgccgaggg gatgtaccgg tggtacagca gcgaggagtc cgaggagaag
     5941 ccctcctcgc ccatcagctc ctcgtagtac aggcccccct cgggggtgcg gtgctgggtg
     6001 tgccgcttgg gcggcaccga gcccagctgc cggtagtacg ccatcgccct gtctctccct
     6061 gtcgtccgtg actctccgtc agaggttgcc gcgccggtcc tgctcgcgct cgatggcctc
     6121 gaagagcgcc ttgaagttgc ccttgccgaa gcccagcgaa ccgtgccgct cgatgaactc
     6181 gtagaagacg gtcggccggt cgccgatcgg cttggtgaag atctgcagca ggtagccgtc
     6241 ctcgtcgcgg tccaccagga tgccgcgcga ctgcagctcc tcgatcggcg cccggacgtg
     6301 gccgatccgc tcgcgcagct ccgggtcctc gtagtacgag tccggggtgg agaggaactc
     6361 gacgccgcgc gagcgcagca cgtccacggt ggtcaggatg tcgttggtgg ccagcgccat
     6421 gtgctggcag cccgggccgg tgtagaactc caggtactcg tcgatctgcg acttcttctt
     6481 cgcgatcgcc ggctcgttca gcgggaactt cacccggtgg ttgccgctcg ccacgacctt
     6541 cgacatcagc gccgagtagt cggtggcgat gtcgtcgccg acgaactccg ccatgttcac
     6601 gaagcccatc acccggttgt agaacgacac ccactcgtcc atcttgccga gctccacgtt
     6661 gcccacggcg tggtccagcg cctggaacag ccgcttcggc gcgccctcgg ggcggaccac
     6721 cgtcgactcg cgggcgacgt agccgggcag gtacgggccg gtgtagcggg agcggtcgac
     6781 cagggtgtgc cgggtctcgc cgtacgcggc gatggccgcg cggcgcacgg tgccgtgctc
     6841 gtccgagacg tcgttgggct cctccaggac ggtggcgccc tgggcgcggg cgtgcgcgat
     6901 gcacttgtcc acgtccggga cctccatcgc caggtcgacc acgccgtcgc cgtgccggcg
     6961 gtggtggtcc agcagcgggc tgtccggcgt cacgccgccc tcgatcacga agcggcagga
     7021 gcccgagcgc agcacgaacg acttgcggtc gcggcggccg gtctccgggc ccgagtaggc
     7081 gaccagctcc atgccgaaca cggcctggta gaactgcgcc gtctgggtcg cgttgccgac
     7141 cacgaagacg accgcgtcct gggcggtcac cgggaacggg tcggtcgagg cgtcgtactc
     7201 caccaggccc accagggtgc gcagctgctc ggccgtcaga ccggcctgca gctcctcggg
     7261 ggtcagttca acagcggcgt cggcggtcat ggggcattcc tccacgtcga ggtcggttgc
     7321 gcagagcttg ctcctgctcg gtggggtggg caacaggtcc gattccggct gctcaatgtg
     7381 tacaagatga gcagccggac cgggtccggg ctgtacggat tgctcagtgc tccacccgat
     7441 cgcctccccg gccgggcggg aagtgccgga cgaaccagcc cgccgccagt gcggcgaccg
     7501 cctccagcgc gccgggctcc tcgaacaggt ggccggcgcc cgggacgacc tgcagggcgc
     7561 tctcgccgcc cagttcggcc cgggcctgcc ggttccactc cagcacctcc tggtccgcgc
     7621 cgccgacgat cagcagcgtc ggcaccgtca ccagcggcag ccgggcctcc gcgaggtccg
     7681 gccggccgcc gcgggccacg atcgccgccg gggcgctgtc cggctcggcc gccgcccaca
     7741 gcgccgccgc cgcgccggtg ctcgccccga accagccgta cggcaggccc gccagcgccg
     7801 ggtggcgcag cgcctcccgg gtcgccccgg ccagccgccc gcccagcagg cccgggtcga
     7861 acaccttcca gcgctcgtcc gcctcgccgg gcgtcagcag gtcgaacagc acggtcgcca
     7921 gccgctcccg gtgcaggtgc gcggcgaccg cgcggttgcg cgggctgttc cgccccgagc
     7981 cgctgccgtg cgcgaacagc acgacgcccc gcgggtgttc gggcacggcg aggtcggccg
     8041 ccccggtgcc gagccggagc tcctgcccgg cgggcccggc tgccttcggc ggtccggccc
     8101 ggtcgagcgc ggccagcacc tcggcgtccg tggtctgccg gaagtcccgg tagaacgcgc
     8161 cgaccgcggc gaacccgtcc ggggtgtcca ccgccaggta gccgtccgcc gcgtcgccca
     8221 actgccgggc ccagccgggc ggggcgaccg gcaccgccag caccacccgg gcggcgccgc
     8281 gggcccggac gatccggcag gccgcccgcg cggacgcgcc ggtcgccacc ccgtcgtcca
     8341 ccaccagcac cgtccgcccg gccagcggca ccggcgcccg accgccccgg tagagcgccg
     8401 cgcgccgggc cagctcggac cgctcccggg cctcggccgc cgcgaacgcc tccggcggga
     8461 cgcccgccgc gtccaccacc tgctggttca ccacccgggc gccgtcctcg cccaccgccc
     8521 ccatcgccac ctcgggctgc cccggcaccc ccaccttgcg caccacgcac acgtccagct
     8581 ccgcgcccag cgcggccgcc acctcggcgg ccaccggcgc gccgccgcgc ggcagcgcga
     8641 ccacgacggc gccgcgcagt tcgggcgcct cggacagcag ggccgcggcg aggcggcggc
     8701 ccgcgtcggc ccggtcggtg aagtgcatgg cgggaacctc tccacttccc acggtacgcg
     8761 cccgttccgg ggcataagaa aaaaataagg acaaaccggt gggtagcgtt atttaccgcc
     8821 cagggcgggt agcgaccaat tggctcgcat gtcctgacta cgaggaggtg gtcccggtgt
     8881 cgacccacac gccctcgggc atggaacacc atccggacat cctggccctg cgtgaacacg
     8941 cggagcgcgt cacatccacc accgccggac aggggacgga agcactcgcc gtctgcgccg
     9001 gactcttcct ggccatctcc ccctgggtgg tcggcttctc cggcttcacc gggctggcca
     9061 tcagcaacct ggtgctcggc atcgcctacg ccgtcctgat ggccggctac ggctccgcct
     9121 tcggccgcac ccacgcccgg gcctgggcgt gcgtggcgat cggcgcctgg acggtcatcg
     9181 ccccctgggc ggtcaacggc ggtgcgcacg tccgccggac catcctgacc aacgtcatca
     9241 ccggcggcgt catgacctgc ctggccctgg ccgcggtcgg catggtcttc gcgggcatga
     9301 cggcacgccg caggtagggc acggcgcagg ggcccggagg cccccacggc ggcgggaccc
     9361 cggacggggt cccgccgccg tgcagtgaca ggttttcgtc aagtttcggt caagccgccg
     9421 gccgcggtcg tggacacccg tcgcgcgcgc ccccgaagtg gttcgtgcgc ggccgggagc
     9481 agtggtgatc ccggtttccg gtactgaaac cccgaaccgg tccggtcacc gggaacggac
     9541 accccccgga cgcggcgcga gggacggaag tgcaggccgg gggcgccggg ggcggagcgg
     9601 tacgggtggg gcggaggttg gccgggacgg cactcaccac atcgtgggaa gccggggaac
     9661 agtggtgcct cgcgccggac cggacaaccg ttcgagccgg ccgcggcccg gaccaccgtc
     9721 cgggcggacc cacgagccct caggagggga tatgcgcacc gagaccaccg tgcagtccga
     9781 caccaccgac ttcgacctgg acctgcgcat cgcggacgtc gcggagcaga ccgaggagtt
     9841 cggccggggc acctacacct cgccgagcag ctacgccatc ggcacccgtt gcccggtctg
     9901 ctgctgaccg gcccccggta gtcctcgcgc ggggcgggct gcggcccgcc ccgcgctctc
     9961 cgctccctcc ccacccgcga acccgaggag cccgacgaac gtgcgcgcag agcccgaccc
    10021 gttcgacgtc cgggaaccgg tcctggtccg gacggccggc accccgcgga ccggcaccga
    10081 gacccggatc gacccggccg accccgtccc gggcgcgcgc cgcctcgccg ccgacccgct
    10141 gctgcgccag gccgtcgagg tcgccagcgg cagcctcgcg ctcagcctgc aacggctcgg
    10201 cgaacccggc ggcgccgccg ccctcggccg caagcgcacc gccagcgccg cccgcaccct
    10261 cacccgctac gcccgccgct ccggcggccg ccccaccccg ttcggcctgt tcgccggcgt
    10321 cggccgggcc cggttcgggg ccgccgccga cgtcccgccg cccggccccg gacaggtcag
    10381 ggtccgcctc gacggcggct ggctgcaccg ccgggtgctg gactggctcg ccgtgcccga
    10441 ggtccgccgc cgggtcgacg tcgtcctcga cgacctgacc gtgctgcgcg acggccgcct
    10501 gctgcggcac accggcgaac gcgaggtctc ggtgcgcgac aacccgctgg tcacccgggt
    10561 ccgcgaggcc gccgcccgcc ccgtcgggta cgccgacctg ctcgccgacc tcaccgcgcg
    10621 cttccccgcc gtcgcccccg aacggatcga cggcctgctc gccggactcg tccagcacgg
    10681 cttcctgctc acctcgctca ccccgcaccg cgtcgacgac gccctgctgg accggatcga
    10741 caccgccctc gacggcgccg tccccgccgc cgccgaagga ctgcgcgccg tccgcgccgc
    10801 cgccaccgcc cacgaacgcg accgccccgg cgaaggactc gcctcctggc ggcacctgct
    10861 ggaacaggtc cgcgccctcg accccgacga ccgggccggc gaacgcccgc ccgtccaggt
    10921 cgacctgcgc accggcgccg acctggtgct gcccgccgcg gtcggcgagg aggtgcgccg
    10981 ctacgccgcc gcgatctggg cgatcacccc cgagtggacc accctcgacc acctgcgcga
    11041 ctaccgggac cgcttcgtcg agcactacgg caccgccagc gccgtcccgc tcgccgacct
    11101 cgccgacccg caccgcggcc tcggcctgcc gcccgagtac ggcggcgccg cgcccgccca
    11161 ctcccgctcc ggccccggcg acgacgccga ccggccgcgc cgcaacgccg tcgccgaact
    11221 cgtccagcag gccgtgctgg ccggcaccga cctggtcctc gacgacgccg acctcgcccg
    11281 gctcgccgac gccgccggcc acaccccggg cagcagccgc ccgccgcgca ccctggaact
    11341 ctgcttccaa ctcctcgccg actccgccgc cgccctcgac cgcggcgagt tcctgctgct
    11401 cggcagcccg cacaccggct cctggacggc cggcgccacc gccggccggt tcgccgacct
    11461 caccggcctc accgccgacc tggccgccct cgccgccgga cccgccgacg acggcgccct
    11521 gcccgtccag gtcgaactcg ccccgcgcga cccgcgctcg ctcaacatcg tccaggtgcc
    11581 gccactgctc ccgcaccgcc tgccgatcgg cgtcgccgcc gaccgcggcg acccgcactg
    11641 cctggactgg cgcaccctgc tggtcgccgc cggcgaggac ggcctgcgcc tgctccaccc
    11701 cgacaccggc cgccccgtcg tcccggtctt cccgcacatg ctcgccctgg acgcccaggc
    11761 cccgcccgtc gcccgcttcc tggccgacct ggccgccgcc cgcccccggg tctggtccgg
    11821 ctgggactgg gcgggcctgg acaccctgcc ctacctgccc gccgtccgcc acggccgggt
    11881 cctcgccgcc ccgcgccgct ggctgcccgg ccgccgcctg cgcgacgccg cccgcaccgc
    11941 cggacccgcc gcctggaccg agggcctgcg gacctggcgc gagcgctacc gggtgcccga
    12001 ccggctgcag atcgccagca acgaccggat gttcccgatc gacctgcgcg aggactggga
    12061 caccgacctg ctgcgcgccg aactcaccgc ccccgaaccg cggttccagc tcttccagga
    12121 cctcaccgcg gacggcgccg gactcggctg gaaccacggc cgcagcaccg agatcgtcgt
    12181 cccgctgctg cgcgcccccc gccccgcccc cgccggcacc cgccccccgc tggccaggtc
    12241 cgcggtccgc accgccccca cccggatcca cctgcccggc gaggactggc tgttcgccaa
    12301 gctgtacgcc gaacccggca cccacgacac cctgctcgcc gaccacctgc ccgccctgct
    12361 cgccgacgtc gaaccccacg tcgaccgctg gttcttcctc cgctaccgcg accccgaacc
    12421 ccacctgcgg ctgcgcctgc acggcgaccc cgccgccctg gccggccacg tcctgcccgc
    12481 cctcgcccgg cacgtgcgcc ggctcgtcgg gaccggcgcg ctgcgcacca cggcgctcga
    12541 cacctaccgg cccgagaccg accgctacct cggccccggc gcccaggaag ccgccgaacg
    12601 gctcttccag accgacagcc gctccgcgct gctccagctg cgcgcccgcc gggccggcgc
    12661 cgccgccgtc cccgacgagg tcctcgccgc caccggccac gccgtgctgc tggactcgct
    12721 cggcgactgg gactggtgcg cctgggtggt ccacctcttc gagaagggcg ccgaccaccg
    12781 cgcccaccag cgccaccgcg ccctcgccga ccggctgatc cgccccgacg acaccgcccg
    12841 gcacgccgcc gaacacctcg gcatccccga cctcgccccg ctctggaccg acacccccgc
    12901 cccgcgcgac ttcggccggc tgctgctcgc cgcacccgag gccgaccgcg acgaggccct
    12961 catgtcgctg ctgcacatgc ggcacaaccg cctgttcggc atcgacccgg ccgccgaggc
    13021 ccgcggctac gccgtcctgc gcggcgcggc cagggccctg atcgggcgca agtcacatgc
    13081 aggggaaggg aagtgacgat gcctcagttc cttccggtcc gcccggccgc cgaccggggc
    13141 cgcggacgga gcggcggggc gacgtcgtgc cggttcccgt ccgggcgagc cgtcatcggt
    13201 ccgggccccg gtggctgccg ctgctgctgc gcgggccgga gcaggtgcgg tgttgcgccg
    13261 gttcccgccc gtccgtcccg ccgccgagcc gggcaggtgg ggcgccagtt cccgtccgtc
    13321 cgaaccgcca ccgaccggag cccccgatga ccgacaccgt gcaggcgact gccgtttccg
    13381 cggaacgggc ccggttgcgg gcggccgccg ggcagttgtc cgacctgatc ctggaccggc
    13441 tcgccgaccc ggccgcgacc gtggccgcca cccggatccc cgccgaggcc gccgacgacg
    13501 gggtggccga gaacgtctgg gcggaactga cgctcggcag cggcagcccc gggctgtcgc
    13561 tggcgttcag cggcggggcc cggccgggca ccgagcgggc cgcccgggcg cacgggtacc
    13621 tggcggtggc gacccgggcc gcgggggccg gcgacaccgt gcccagcggg atcttcaagg
    13681 ggcccggtgc gctggccttc gccgtgctgg ccgcccaccg cgccaccggc ggctacaccg
    13741 gggcgctgca ccggctcgac gcctaccagc ggcaactcgt gcgcaccgcg ctgcccgccg
    13801 tcccggacgg gccgctggcc accatcgggc actacgaggt ggtgcgcggg atgaccggcg
    13861 tcggccggta cctgctggcc cgcgcggaga gctgcggcga ggagctggaa ctggtcctcg
    13921 gctacctgat cgagctggcc cgcggcacca ccgcgcaccg cggggcgcgc gtcccgcgct
    13981 ggtgggcgct ggacgcgccc cggatcggct ccgagcacct gctgccggac ggccacctca
    14041 acctcggcct ctcgcacggc gtcgcgggcc cgctgatgct gctcgcgctg gcctggcgcg
    14101 acggcgtccg gctgcccggc caccgggagg ccctggagag caccgccgac ctgctggtgc
    14161 gctgggcggt gcgcgacgag cacggcagtt actggcccgg ttacctcggc ctggacgcct
    14221 acctggccgg gcccgacgcg taccgcgaac ccgccggctg gccgtcctgg tgctacggcg
    14281 cgcccggcgt ctcgcgcgcc ctgcagaccg ccggggccgc gctcggccgg ccggagtgga
    14341 cggccgtcgc tcgcgactcg gtcgagcggc tgctgcgggt gccgctcgac gactggggcg
    14401 tcaccgacca cgcgctgtgc cacggctggg ccggggcgct gcaccaactc gggcggctga
    14461 acgagcactt cggcgaggag cggatcgagc ggcggcgcga cgagaccgcc gcccggctgc
    14521 tggccgggca cgacccggac gccccgttcg gcctgcgctt caccatgacc cgcaggccgt
    14581 tcgccagcga cgtctccggc tacctggacg gggcggccgg cgtcgcgctc gccctcgatt
    14641 cgtacgcggc cggcggcacc ccgcacgact gggacatgcc gctgctgctg tcctgaccgg
    14701 ccctgaccgg ccgtcagtcg gcgtcagtcg gcgtcctgcg ggcgggtcat ccgcaggacg
    14761 tcgagcgcct cgtcgagctg ggcctcggtg agcaggccgc gctcgacgta gccgcggtcg
    14821 aggaccacct ggcggatcgt ccggcgctcg gccagcgact gcttggcgac cttcgccgcc
    14881 tcctcgtagc cgaggtagcg gttgagcggg gtgacgacgg agggcgagga ctcggcgtac
    14941 tcgcgggtgc gctcggcgtt ggcggtgatg ccgtcgacgg tgcggtcggc cagcaggcgg
    15001 gcggaggtgg tgagcaggcg gaccgactcc agcacgttgc gggcgatcac cgggagcatc
    15061 acgttgagct cgaagttgcc gctcgcgccg gccaccgtga cggtggtgtc gttgccgatc
    15121 acctgcgcgg cgaccatcag gaccacctcg ggcagcaccg ggttgacctt gccgggcatg
    15181 atcgaggaac cgggctgcag gtcggggagg ttgatctcgg cgaggccggt gcgcgggccg
    15241 gagcccatcc agcgcaggtc gttggcgatc ttggtgaagc cggcggcgat cgtgcggagc
    15301 tgtccgctga gctcgaccag gccgtcccgg gcgccctggg cctcgaagtg gtcgcgggcc
    15361 tcggtcagcg gcaggccggt ggcgcgggcg acctcggcga tgacggccgc cgagaagccc
    15421 ggcggggtgt tgatgccggt gcccaccgcc gtgccgccga gcggtagttc ggcgacccgg
    15481 gggagcgtgg cgcgcaggcg ctcgacgccg taccggacct gggccgcgta gccgctgaac
    15541 tcctggccga gcgtcaccgg agtggcgtcc atcaggtggg tgcggccgga cttgacgacg
    15601 cccgcgaact cggcggactt ggcctccagc gcccgcgcca ggtgctccag cgccgggacc
    15661 agctcgtgca ggaccgcgcc ggtggccgcc acgtggatcg aggacgggaa gacgtcgttc
    15721 gacgactgcg aggcgttgac ctggtcgttc gggtgcaccg ggcggcccag gcgctcggcg
    15781 gccagggtgg cgatcacctc gttggcgttc atgttcgacg aggtgccgga gccggtctgg
    15841 aacacgtcca ccgggaactg gtcgtcccag cggccctcgg ccacctcctc ggccgccgac
    15901 cggatcgccg ccgcggtctc ctcgtccagc acccccagcc cggcgttgac ggtggccgcg
    15961 gccgccttga tccgggccag cgccgcgatg tgggcgcgct ccaggcgctg ccccgacacc
    16021 gggaagttct ccaccgcgcg ctgggtctgc gcccgccact tggccgccgc cgggaccctg
    16081 acctcgccca tcgagtcgtg ctcggtccgc cactgctgcc cgtcctgctg cccgtgctgc
    16141 cggtcctgct gtccgtccgc catggtcggt acacctcctg gatcggtcag ccttccacgg
    16201 gcgcccggca ttcccggccc ggccggaccg cgtgtcgccg acggccgccg ccgcggcgcc
    16261 cttgaccggg cggcgtaccg accggtaggg acagcggtgg caccaccctt gcccacaccc
    16321 tccgaggagc ccgcccatgg ccaccgccgc acccgccggc cgacccgacc cgctcgacct
    16381 gctcggcgtc gacgaactgc tcaccgagga cgagcggctg gtccgcgaca gcgtccgggc
    16441 cttcaccgac cggcacgtcc gcccgcacct cgccgactgg tacgagcggg gcaccttccc
    16501 ggtgcgcgaa ctcgcccccg aactcggcaa gctgggcgtc ctcggcatgc acctggaggg
    16561 ctacggctgc accggctcca ccgccaccga gtacggggtg gcctgcatgg agctcgaagc
    16621 cgccgactcc gggctgcgca gcttcgtctc ggtgcagggc tcgctcgcca tgcgctccat
    16681 ccacgcctac ggctccgagg agcagaagcg gcactggctc ccggagttgg ccgccggacg
    16741 ggccgtcggc tgcttcggcc tcaccgaacc ggaggccggc tccgacccgg cctcgatgcg
    16801 cacccgggcc cggcgcgacg gcggcgactg gatcctggac ggcgccaaga tgtggatcac
    16861 caacggctcg gtctccgacg tcgccgtggt ctgggcgggc accgaggacg gcgtgcgcgg
    16921 cttcctcgtc ccgcgcggca cccccggtct caccgcccgc gacatccccg gcaagctctc
    16981 cctgcgcgcc tccgtcacca gcgaactcgc cttcgacggc gtccggttgc ccgccgacgc
    17041 gcagctcccg caggcccgcg gcctgcgcgc cccgctggcc tcgctcggcg aggcccgcta
    17101 cggcatcctg tggggcaccg tcggcgccgc ccgggactgc taccgggccg ccgtcgacta
    17161 cgcccgcgac cgggtccagt tcggccgccc gatcggcggc ttccagctca cccaggccaa
    17221 actcgtcgac atggccctgg agttggagaa ggcctacctg gtcgcggtgc ggatcggccg
    17281 gctcaaggac gcgggccgcg cccaggccgc gcacatctcc ttcggcaagc tcaacaacgt
    17341 ccgcaccgcg ctggagatcg cccgcaccgc ccgcaccatc ctcggcgcca acggcatcac
    17401 caccgcctac ccggtgctcc ggcacgccaa caacctcgaa tcggtcctca cctacgaggg
    17461 cacctcggag gtgcacaccc tggtcctcgg cgaggcgatc accggcgagt ccgcctaccg
    17521 ctgatcgccc ggcccggtcc caccgcccgc tcccaccgct cggtcctcct gccgggaggg
    17581 gcgggtccgc cggaagtcgg gggtcggggg gccggggtcc gacttccggc tgacccgggt
    17641 cggtacctgg tgcgcatgga tccgggggac gggcgcgccg aggatggagg gtaagggttc
    17701 ggagcggcgg aaaaggggtg cggggcgatg ggcggcgagc ggagcaggcg ggcggcggcg
    17761 acggtggtgg tcggcggggc ggccgcggcg atgctgctgg tgatggtggc tccggcggcg
    17821 atccagcggg tgcaggaccg gctggaccag accgtccgct accccaacgg gtccgcggcc
    17881 aaggccgacc ggaccgaggt gccgcgctgg ctgcccgact cggccaccgg catcgccttc
    17941 ctggcgtccg gggacggggg cgagcggctg atccgggcca ccgtcccgga ccgggcgctg
    18001 cccacggcct gcaccaccac cggccacacc ctggacgacc cgcacctgcg cgcgcactgg
    18061 ttccccaccg acaccccgcg gcgggccacc gcgcactgcg ggcagtacga cgtcgcgctg
    18121 gtcggcgacc agctctacgg ctggcggggc gccccggccg ccgccggggc ccgcaccgcc
    18181 ggtccgaccg gctgacgggg gcgccccggg cgggggtcgg cttccccggc ggcgggcgga
    18241 tgggatagga cggtgcgcac accccgccat ccgtgaggag ccccatgcca ggcccgaccg
    18301 tcgaccccga cggcgaccag accgcacccg acgtcccgct ccgtccggcg caggaggccg
    18361 cgcaggcccc gcagcgtgcc ccgttcgcca ccgccaccgt gatcaccctg ggctgcctgg
    18421 tcgcgctcgg gccgttcacc accgacctgt acctgcccgc gctgcccgac ctgaccgcgg
    18481 acctgggctc caccgccgcg gccgcccagc tcaccctgac cggttcgctg ctcggcatgg
    18541 tgctcggcca gctgctgttc ggcccgctca gcgaccggct cggccgccgc cgcccgatgc
    18601 tggcgggcct ggccgcgttc accgccgcca gcctgctgtg cgcgttcgcc gactcgatgc
    18661 cgctgctggt ggcgggccgg gtggtgcagg gcgcggcggg ctcggccgcg ctggtgatcg
    18721 cccgggcgac cgtccgggac cggttggagg ggaccgcgat gatccggttc ctggcgacca
    18781 tgggcctgat ctccggcctg gccccgatcg tcgcgccgct ggccggtgcc cagctgctgc
    18841 acgtcaccga ctggcgcggg accttcgtcg cgctggcgct gctgggcgcg gtgctcaccg
    18901 tggcctgcgg gttcggcatc ggggagacgc tgccgccgga gcggcggcac ggcggcgggc
    18961 tgggcaccac ggtccgggcg atcggcgggc tgctgcgcga ccgggtgttc ctcggctacc
    19021 tgctggtcag caccttcgcg ttcggcgcgc tgttcgcgta cgtcggcggc tcctcggtgg
    19081 tgctgcagga ggtgtaccgg atcaccccgc agacctacag cctggtgttc gcggtcaact
    19141 cggtctcgct gctggccgtc acccagttca acgggcggtt cctggtgcag cgctactcgg
    19201 agcggacgct gctggtctgc ggcctgggcg cggcggcgct ggccggggcc gccgtggtgc
    19261 tgtgcaccac ggtgtgggac accgggctgg ccggggtgtg gcccgcgctg acggtgctga
    19321 tgggcgcgat gggcgtcatc ctgccgaacg ccaacgggca ggcgctgacc atggccccgc
    19381 acgccgccgg gtcggcgtcc gcgctgctgg gcaccggcac ctacctgtgc ggcgcggtgg
    19441 tcgccccgct cagcagcctg ggcgggcacc cgtccgcgac ggtgctcggc gcggtggtgc
    19501 tgggctgcgc gctgctggca ctgggatcct tcctgccgct gtgccggggg cgctgagacc
    19561 gcggggacgg gggaggaagc ggccgggccc ggccggtggc gggtgccacc ggccgggccc
    19621 ggttcgtgga gcggggggtg tcaggcgatc gagaagtcgt cgccgtagac cgagccctgg
    19681 ccgtaccagc cgtgcaggta gaccgtgacg gtgccgttgg cgccggtggt gaacgggacg
    19741 ctcaccttgg tccaggagga gccgttggcc caggtggagg cggtggcgcc gccgctgacg
    19801 ccgacgtacg agtacgggcc ctggacccag gcggtcaggg tgtacgcgtg gttcggggcc
    19861 agggtgacgg tctggtcgca ctcaccggtg gtgccggcgg tgggcgccgc ctgcagggcc
    19921 ttggagccgc cgtgcaccgg agtggagacc acgccgccgc cgctctggca ggtccacggg
    19981 gcgaggccgc cctccaggtc gccgttgacc aggccgccgg tcggggtggt gccggtgacg
    20041 gtcagcgcgt aggtggcggt gtgggtcttg cccgcgccgg tgccggtgac ggtcagggtg
    20101 taggtgcccg gggccgcggc ggcggtggtg gcgacgttca gggtggcgga gccgcccgcg
    20161 gtgacgctgg aggcgctcag cgaggcggtg acgcccgccg gggcgccgga gacggtcagg
    20221 ttgacggtcg cggcggtgcc ggaggtgacc gcggtgttca cggtgctgga ggcggctgag
    20281 ccggcctgga ccgagcccgc ggcgggggcg agcgcgaccg agaagtcgga ggcggtggtg
    20341 ccgccggtga cggtcagggt gtaggtcgcc gagtgggtgc cgctcgcgcc ggtgccggtc
    20401 acggtcagcg ggtagctgcc gttggcgacg cccgcggtgg tggcgacgtt cagggtggcg
    20461 gagccgcccg cggtgacggt ggaggcgctc agcgaggcgg tgacgcccgc cggggcgccg
    20521 gtgaccgaca ggttgacgct ctgcgccgag ccggaggtga ccgcggtgct gacggtcgcc
    20581 gaggtggacg cgccggcggt gaccgagccg gtggccgggc tcagcgacac cgagaagtcg
    20641 ttggccggga cggaggagct ggtgaacttc gagaagatgt ggctgaagtc ccaggtgccc
    20701 tgcgcgatgc cggagcagct gtccgacccg gcggtgcccg cgcagccgcc gttgtcacgc
    20761 tgcagcgccc agaaggacag ggtgttgatg cccttggaga cggcccagtc gtagaccgtg
    20821 ttggcgttgg cgacggtgaa ggtctcggcg gcgccgaagt cgtcgatgcc gatcatctcg
    20881 atgatgccga tcgagttcca cagctgggtg gaggtcttcg tcgggtacag cttggccagc
    20941 tggttgtaca ggccctgggc ggaggtctgg gtgtccgcgg ccatgtcgtg cggctggttg
    21001 tcgtagtagt cgaacgtcat catgttgacg acgtcgatcc gcgcgttgtt gctgaccgcg
    21061 ttcttcagca ccgcgaggcc gctggaggcc aggccgctgg tggtggtcgg cagggtgtag
    21121 ctgaactgga tgttgcggcc gttggcggcg gcccagtcct cgacgatctt gatcgccttg
    21181 ttgcggcggt cgatgccggc cgtgttggtc agcgagttgt cctcgatgtc caggtcgatc
    21241 cgggagacgt cgtaggtggt gatgacgttc tcgaacgcgg cggcgatctg gttgacgtcc
    21301 gtgcaggagt cggcgatctc ggtgccggtg ttgtcggcgg tgtagccgcc gaaggacggg
    21361 atcacgtcgc cgccgttggc gcggatggtg gcgatgtcgg cgccgaagac cgagttggac
    21421 accggcatcg aggtgtcgcc gttccacagc gcggtgcagg agcccttggt ggcggcctgc
    21481 aggaacgcca tggtcaggtt cttggcgccg gactgggcgg ccagggtggc cgggttgtcg
    21541 ccggtccacg cctcgaagta cggggcgaag acgtgctgcg gcagcggggt ggcggcctgc
    21601 gcgggggcgg agatcagccc cagcgaggcg gccgccatcg cgccggtggc gagcagcgct
    21661 tggagtggtc ggtgaaggcg catcgagtct ccatcaggca tgggaggagg gcccgcgtgc
    21721 cggtgttcgg gcacggggcg tgggtctggc ctggtacagg gagtgccggg gtggtgcggg
    21781 gcagtactgc ttgccccggc cggtggtcac acccccacga tgcgttccgg tcgggaagta
    21841 cagcggactc atggttggtc tggaccactg cgtctgtcaa gactctttac agttcactgg
    21901 agcacaggtc ggagcaggcc cggagagctt taccaagcct tgtacatcag ggccttgacg
    21961 tgccgtcggc cccgcacccg actgctcggt gcggggccga cgggcggcgc gggtcagttc
    22021 aggccgctgc tcttcagcca ggccgcggcg accgccgccg ggtcctcctt gtcgaccgcg
    22081 acgcgcttca tcagcgcggt cagcccggcc gtgtcgagct tcgccgagac cgcgttcagc
    22141 gcggccgtcc cggtggcgtc cagaccggcc tggttcacca gcggggtgac gttctgcgcg
    22201 ctgaacacgt tcttcgggtc agccagcgac accagcttca gctggaccag cttcgggtcg
    22261 gtggtgaaca cgttgccgac ctggacggtg ccgtccttca gcgcgttggc ggtggtgtcg
    22321 ccggtcggct tccactcctt gaaggtcagc ccgtaggcgt ccttgaactg ctgctcgcgg
    22381 cgggacttga actccggcgg gccgccgacc accaggtcct gcgccttgcc cgccaggtcg
    22441 gctatcgact tcacgcccag cttgtcggcg gtctcctggg tgaccgtcag cgagtccttg
    22501 tcctcggcgg ccgaggagtc caggatcgcc agcccggccg gcagcttggc cttcagctcg
    22561 gtgttcaccg cgtccttgcc ggtggcggtc gacttggcgt ccaggtagcc cagcagcgcg
    22621 ccgttgtact ccggcagcac cgtcagcgca cccgactgca gctgcccgta cagcagttcg
    22681 cggctgccga tgttgaactt ctcctccacc ggcacgccct tggccttcag ggcctgcgag
    22741 tagatcgagg cgagcagcac gttctccggg aagttcgccg agccgaccac cacggtcttc
    22801 ccggagcccc cggccggggc ggacgccgcc gggccggagg acttcgcggc cagcgggtcg
    22861 ccgccgccgg aggaggagca ggccgccgcg cccgccagca ggaggacggc gagggcggtt
    22921 cggaccggac gggtcgtcat ggggattcct tcacgagagc gggggagccc gcgggatcgt
    22981 cgtcgggagc ggagccgccc gcggacgcgc ccccgccacc ggcggaaccg gcggcacgga
    23041 cacggcggac ggcacggacc ggtcgcgcgc cgggcggcga cgcgagccgg acgaacaggg
    23101 cgaacagcag ttggacggcc accgccagca gcaccaccag cagggcgccg ccgaccgtgg
    23161 tcgggtagtt ccgggtggcc agcccgtcga tcacgtaccg gcccagcccg ccgaggccga
    23221 cgtacgcggc gaccgtggcg gtggcgatca cctgcaccga cgccgtccgc acccccgcca
    23281 gcagggtcgg cgcggcggcc ggcacgcaca cccgcagcag ggtctgcggg tgcgtcaggc
    23341 cgatgccgcg ggccgcgtcc cggacgtccg ggtcggtgcc gcgcaccccc tcggcggcgg
    23401 ccaccagcat cggcggcgcg gccagcgcgg tcagcggcag cagcaccgcc gtctcgccga
    23461 cgcccgccag cagcaccgcc agcgtcacca ggcccagggt cggcagggcg cgcgccacgc
    23521 cggccagcgc cgtcaccagg aacagcccgc gccccgagta gccgatcagc aggcccagcg
    23581 gcagcgccac cagcgcggcc aggccgagcg cctcggcgga gaacgccagg tgctccagca
    23641 cccggtggac gatcgagtcc ggcccggagc ggtgcgccgg atcggcgaag aagtcgtgca
    23701 gccagcccag ccagttcacc gcgccacccc ccgcgaccac ggcgccagca cccggcgggc
    23761 cgccagcagc agcaggtcgg cggccagcgc gagcagagcc accagcacga tcccggccag
    23821 gatcggcgtc gggaaggtcc gctggaagcc gtccacgaac aggtagccca ggccgccccg
    23881 gccgaccagc gcccccaccg ccgccagcga gatcgaggac accgcggcca cccgcagccc
    23941 cccgatcaag tacggcacgg acgccgggag ttcgaccgcc gccagccgcc gccacgggcc
    24001 gtagcccatc gcggtggccg cctgccgcac cggctccggc accgcccgca gcccgtccac
    24061 cgcggtcggc agcagcaccg ccagcgcgta gcaggtcagc ggcaccatca cggtctcccg
    24121 ggtggccagc cccgtgtacg ggatcagcac cacgaacacc gccagcgagg gcagcgcgta
    24181 caccacgttg aacaccgccg ccagcggctg gtacagccgc gggaagcgcg cgcaggccag
    24241 gcccagcggc accgccagca gcagcgccag cagcaccggc accagggcga tcaccgcgtg
    24301 gtcggccgtc aggtcgccca ggtagccgag gtggtcgccg agccagcgcc agcggatcag
    24361 cggctcaccg tccagcatgc ggcacctgcg cagcgtcggg ggcctccggg gtcgccgggg
    24421 tcgccgtccg ggtcttcccg gtctccgggg tcgtcggggt gctaccggtc tgcggggccg
    24481 ggccggtctc cggggccttc gcctggggct gtgcggcctc ctgggaccgg gccagtgcct
    24541 cgacgacggc ggcgcggctc gcggtgccga ccgcgcggcc cgcgtcgtcc accgcgacgg
    24601 ccaggccgga cggggcgagc agggccgcgt ccagcgcgga gcgcagcgag tcccgggacg
    24661 gggcgaacac cggggccggg tggcgctcgg cgccgc
//
