LOCUS       NZ_CP113837            21107 bp    DNA     linear   CON 26-JAN-2024
DEFINITION  Kitasatospora sp. YST-16 chromosome, complete genome.
ACCESSION   NZ_CP113837
VERSION     NZ_CP113837.1
KEYWORDS    RefSeq.
SOURCE      Kitasatospora sp. YST-16
  ORGANISM  Kitasatospora sp. YST-16
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Kitasatospora.
REFERENCE   1  (bases 1 to 7659304)
  AUTHORS   Mo,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-NOV-2022) College of Life and Environment Science,
            Hunan University of Arts and Science, No. 3150 Dongting Avenue,
            Changde, Hunan 415000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 8.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 95.0x
            Sequencing Technology             :: Oxford Nanopore PromethION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/24/2024 04:37:03
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,903
            CDSs (total)                      :: 6,801
            Genes (coding)                    :: 6,649
            CDSs (with protein)               :: 6,649
            Genes (RNA)                       :: 102
            rRNAs                             :: 9, 9, 9 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 9, 9 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 152
            CDSs (without protein)            :: 152
            Pseudo Genes (ambiguous residues) :: 0 of 152
            Pseudo Genes (frameshifted)       :: 59 of 152
            Pseudo Genes (incomplete)         :: 103 of 152
            Pseudo Genes (internal stop)      :: 5 of 152
            Pseudo Genes (multiple problems)  :: 14 of 152
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:05:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1697403
            Orig. end                         :: 1718510
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP113837.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Mo Ping.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21107
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="8"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21107
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21107
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11107](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11107
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            816..3236
                     /locus_tag="OU787_RS07685"
                     /old_locus_tag="OU787_07685"
     CDS             816..3236
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF023418.4"
                     /locus_tag="OU787_RS07685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_07685"
                     /product="DUF3488 and transglutaminase-like
                     domain-containing protein"
                     /protein_id="WP_268658913.1"
                     /transl_table=11
                     /translation="MTTRAKLTLCAALATALAALCLSPLFRDSFALAPHGLLMIAVTAG
                     AGAGLRALPLPRALVTPLQLLVVLYVLMLTTVQSAMSFGVLPGPGALDAVSTLLSSGGT
                     DIQEYAIPAPATDGLRLIVVGAIALVAVLVDALAVTYRRAAAAGLPLLALYSVAGGLVD
                     SPGGMWLWFLFGAAGFLALLYTEGQDRLTRWGRVFHGTGRSAVTLSNGGRRIGVIALAA
                     ALLLPVFAPAVGPGLFGSVGGHSGEGGGNGNGKGDERSLNLVVALTANLRSSDDTPLLS
                     FSTDSPDADQLYLRIAALSEFNGQEWLPGEQNAQPLPATVPAPEGLAPNLPTTTVRTKV
                     TVTEQLSTAWLPMPYPMSWLEVPNTGNWRFDPAGRTVSGANGQKSKGLTYSVGSVAVNA
                     TPAQLRAAGPAPEDITKRYLGLPSNLPPVVAETAKDVTKGKSTPYDQAVALQQYFTSGG
                     FTYNTKIEARTGPDAIAKFLQDKEGFCVHFAATMAAMSRSLGIPARVAIGFTPGTGNGT
                     DRVVRSSNYHAWPELYFDGYGWMRFEPTPNRGSTPLYSVQQTTPTSAPSTAPSSAAPSD
                     QPSAQPSSSSSCPPQQHRIGDCADEQAQAAHQGDSTSWWLSWPGLVTVLAVLLLLAALA
                     FPLLWRTRLRRRRLGAGRHLSGADGPRLTDEQVLAAWAELVDSAWDLGIPPDEARTPRN
                     AARRLAEDAGLDADAAAAAGRVALATERVMYARESEAPAHLGGDVRTARQALLVRATRT
                     RRLRALLLPASAVRLWWRAQDRAAARRERTAERAAAVRAALAGPFRRRKKEQE"
     gene            complement(3406..3783)
                     /locus_tag="OU787_RS07690"
                     /old_locus_tag="OU787_07690"
     CDS             complement(3406..3783)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135277.1"
                     /locus_tag="OU787_RS07690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_07690"
                     /product="DUF3040 domain-containing protein"
                     /protein_id="WP_030461029.1"
                     /transl_table=11
                     /translation="MPLSEHEQRLLEQMERALYAEDPKFASALEGTGLHTYTRRRVYLA
                     VAGFVAGVALLMGGLVTQVIWVSVVGFLVMLGCAVLAVTAWRRGPAGPGPRQAAAPRRR
                     TGVMDRMEQRWQRRRDEQSGL"
     misc_feature    3887..3900
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.41"
                     /tool="antismash"
     misc_feature    3894..3907
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.11"
                     /tool="antismash"
     gene            complement(4013..4765)
                     /locus_tag="OU787_RS07695"
                     /old_locus_tag="OU787_07695"
     CDS             complement(4013..4765)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018090237.1"
                     /locus_tag="OU787_RS07695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_07695"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_030461028.1"
                     /transl_table=11
                     /translation="MYPTRPRSALRTAVVWEVLREALERRSAELGRPVLEVVDTGGGTG
                     NFAVPVARLGHRVTVVDPSPDALFALERRAAEAGVTELVRAVQGDTQTLPDLVPAGSVD
                     AVLCHGVLEVVDDPAEALGNLVGTLGGGGLVSLLAANRNGAVLARAVAGQFTEARTALD
                     AADGRWGAGDPMPRRFTGEQLDALAAGAGLRVTSVHGIRVFADLVPGVLVDTEPGALDA
                     LLKLELAAAEQPAFHAVATQLHLLAEAI"
     gene            complement(4890..5435)
                     /locus_tag="OU787_RS07700"
                     /old_locus_tag="OU787_07700"
     CDS             complement(4890..5435)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135279.1"
                     /locus_tag="OU787_RS07700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_07700"
                     /product="SAV_6107 family HEPN domain-containing protein"
                     /protein_id="WP_244256735.1"
                     /transl_table=11
                     /translation="MTISRPEPVARPAVDQSAADRPAAGRPDPGRPAVEQPTLPAGRGG
                     DAHPVLRRSSASPAALELLRHAHRTLVHARGRQDPLERYATAHLAALRATAAVLAVRGR
                     PVRHPRRRQAIRPAWELLPEVAPELAEWAAYFAAGARRRAAAEAGIAGAAGPRDADDLI
                     RNTALYLRIVERILALHP"
     misc_feature    5809..5823
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 15.55"
                     /tool="antismash"
     gene            5939..6538
                     /locus_tag="OU787_RS07705"
                     /old_locus_tag="OU787_07705"
     CDS             5939..6538
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018848773.1"
                     /locus_tag="OU787_RS07705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_07705"
                     /product="DUF4126 domain-containing protein"
                     /protein_id="WP_030461026.1"
                     /transl_table=11
                     /translation="MGAVPLIFTSGWASGINAYAVVLLLGLFGRFGGADSVPPVLERTD
                     VLVAAGVLFLCEAVLDKIPYVDSVWDVVHTFVRPVAGATVGALLAAHDPGSLGEVAAGA
                     LGGTTALVSHGVKAGLRMAANTSPEPASNILLSLAEDLSVAGLVTLAIFHPWLAASTAA
                     VLLALGVLVVWFAVSRIRRFWLRRRERRLARAAAAA"
     misc_feature    5975..5988
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 17.74"
                     /tool="antismash"
     gene            6584..7972
                     /locus_tag="OU787_RS07710"
                     /old_locus_tag="OU787_07710"
     CDS             6584..7972
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014141981.1"
                     /locus_tag="OU787_RS07710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_07710"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_268658914.1"
                     /transl_table=11
                     /translation="MARIIVVGAGMGGLAAASRLGTLGHRVTVLEAAGTHGGQVGAYRR
                     DGFGFNTGPGLLALPAVYRDLALKTGREPLEQLVGLRPVDPESRHLFPDGTELLLPNAS
                     RGGVGQALDAAFGAGTGARWGELLNRGRTVWEATRRPLLEEPRPAADPADPYPVPPRRG
                     LSRLLPRGRHTLADAARELGGGPGPAALLGEYALRYGLDPRSAPASATVLPYMEQSFGV
                     WYVDGGLRALADAVFERCGKRGVEFRFDTPVRALEQDGDRVVGVRTDQGVLAADAVLSA
                     VPGLGVAEPAAPAPGRFTVLLALDGARPAGTAHRTVVHAADPAAEARAVFAGRALPDRP
                     TVQVLRPDDPALVPGPDAEAAVLTVTVPAGLTLSDAERDAYAGRLLDHLAAAGLDLRPR
                     VRWRETRLTASVPVPSLAGGHLAQANRPGPAGLYLIGAHAHPGGGLARVGMSASITAGL
                     IGPA"
     misc_feature    6593..6607
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     gene            complement(7980..8798)
                     /locus_tag="OU787_RS07715"
                     /old_locus_tag="OU787_07715"
     CDS             complement(7980..8798)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="OU787_RS07715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="OU787_07715"
                     /product="hypothetical protein"
                     /protein_id="WP_268658915.1"
                     /transl_table=11
                     /translation="MSFGYLLLYGALALVALWLTAELLLQHRAPLHWRALALLGFLGVV
                     AGMRTSSLPVIAAGAAAFGLGQVLVTGSVKRGRPVGWSLRRPDGALPGPLAKVPLLAAA
                     TGATAAAAAEPEPVAPVGEVGPIEDESADPFDDRSAGYEEFQQLDAGVYADDPNAYQVP
                     QQPQYAQQAPQEYGYQQQDHGYAQQEQWADQQQYQQQYQPQFQQPQFQQQPEQQPQLQL
                     IGYDQYGQPVYQDPYTQQQYQQPWIPQQPQPQQQSQQQSPDQNWYYQQQY"
     gene            complement(8904..9818)
                     /gene="metF"
                     /locus_tag="OU787_RS07720"
                     /old_locus_tag="OU787_07720"
     CDS             complement(8904..9818)
                     /EC_number="1.5.1.20"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135283.1"
                     /locus_tag="OU787_RS07720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_07720"
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="WP_030461023.1"
                     /transl_table=11
                     /translation="MALGIPSTRSDRAQTVRDLLAAGDRSFSFEFMPPRNDEGERKLWD
                     AIRRVECLEPNFVCMTYGAGGSSRGRTVDLVGRIATETTLTPVAHLTAVDHSVAELRNI
                     IGQYADQNVRNVLAVRGDPPGDPMGEWVRHPEGVSYAAELVGLIKDIGDFCVGVAAFPQ
                     MHPRSENWDEDIRHFVAKCRAGADYAITQMFFEVEDYLRLRDRVAAAGCDTPIIPEIMP
                     VTNIRQLVRFPQLSGSDFPPDFRRKLESVADDPVAVRAAGLEHATAMAERLLAEGAPGL
                     HFITLNHSTSTLEIYQNLGLHTR"
     misc_feature    9974..9988
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.56"
                     /tool="antismash"
     gene            10001..11107
                     /locus_tag="OU787_RS07725"
                     /old_locus_tag="OU787_07725"
     CDS             10001..11107
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135284.1"
                     /locus_tag="OU787_RS07725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_07725"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_268658916.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 8.3e-45, bitscore:
                     151.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPSIRLPRNPVDAEDVRERVNTTLGAFMAERAALLSGISDDLGP
                     VADALRDFLLDGGKRLRPAFCYWGWRAAGGADDEPGIERAAAALELLQASALVHDDLMD
                     RSDTRRGLPAVHRRFENLHRAGGWRGDREQYGASAAVLLGDLLLIWCDELFQRSGLPVA
                     AVSAAKPAFDLMRTEVMLGQYLDVLEPVAGDSTDAGAIDRARTVLHYKSAKYTIERPLQ
                     VGALLAGAGPDLVDALGCFGLPLGEAFQLRDDLLGVFGDPAVTGKPAGDDLREGKRTLL
                     VAHAMRSLCPADAARLDARLGAPGLDAGEIAALRDLITRSGAPELVEARIDALLAEALT
                     ALDAAPIADGPTREVLRALADAATVRKY"
     gene            complement(11115..11780)
                     /locus_tag="OU787_RS07730"
                     /old_locus_tag="OU787_07730"
     CDS             complement(11115..11780)
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_process="GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /GO_process="GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018384160.1"
                     /locus_tag="OU787_RS07730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_07730"
                     /product="VanZ family protein"
                     /protein_id="WP_268658917.1"
                     /transl_table=11
                     /translation="MDQTLSAARRARRVALLVPALLGAAAVAFLAQRPLGDHAGWNGWV
                     GTVNGIVFLAAAALPVAVLAVWALARRRRAAGVAAGWARRSALAEVGMVYGTVPWVWMI
                     LLPGVDPGGPRRRVNLVPLHDIAEIVGAGPPATAVAQIVGNMLVFAAFGFLAPLRFAAL
                     ASVRRVLALGAAGSVLVETAQYVLRLDRVSSVDDVLLNAVGAALAALASRRWWRRRAS"
     misc_feature    11762..11775
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.61"
                     /tool="antismash"
     misc_feature    complement(11822..11836)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.31"
                     /tool="antismash"
     misc_feature    11887..11900
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.61"
                     /tool="antismash"
     misc_feature    complement(11887..11901)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: strong, score: 22.02"
                     /tool="antismash"
     gene            complement(11999..12646)
                     /gene="thiE"
                     /locus_tag="OU787_RS07735"
                     /old_locus_tag="OU787_07735"
     CDS             complement(11999..12646)
                     /EC_number="2.5.1.3"
                     /GO_function="GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1280: thiamine-phosphate pyrophosphorylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135286.1"
                     /locus_tag="OU787_RS07735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_07735"
                     /product="thiamine phosphate synthase"
                     /protein_id="WP_030461020.1"
                     /transl_table=11
                     /translation="MTAAPTARQRLADARLYLCTDARREQGDLPEFLDAVLSGGVDIVQ
                     LRDKGLEAKQELEHLEVFADAARRHGKLLAVNDRADVAYGARPDVLHLGQDDLPVAVAR
                     RILGEDVLIGRSCHSETEVDTALTEPGVDYFCTGPVWPTPTKPGRHAPGLDLVRHAAAR
                     RPDRPWFAIGGIDAGNLDQVLAAGATRIVVVRALTAAEDPRAAATALAARLR"
     gene            complement(12643..13008)
                     /locus_tag="OU787_RS07740"
                     /old_locus_tag="OU787_07740"
     CDS             complement(12643..13008)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606129.1"
                     /locus_tag="OU787_RS07740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_07740"
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_030461019.1"
                     /transl_table=11
                     /translation="MSEIDPKIDALVPAWLYLPDISERWGVVITEVRAMVKNRTLLAVR
                     RGPNNSLQVPADFIEDDGLVKHLAGTLTVLRDCGFSDQEILEWMFTEDDSLPGSPIQAL
                     RENRGTEVKRRAQAMAL"
     gene            complement(13025..14224)
                     /locus_tag="OU787_RS07745"
                     /old_locus_tag="OU787_07745"
     CDS             complement(13025..14224)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017238820.1"
                     /locus_tag="OU787_RS07745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_07745"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_268658918.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.9e-54, bitscore:
                     182.9, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVAELKATDRVVVVGAGMAGAQTALNLRQGGWNGPLALVGAELHL
                     PYDRPPLSKDVLLGKTDATAFEIDWHGLGVDLLTGRRATGLADGVLHTDRGELPYDALV
                     IATGAAPRTLPGLPGARTLRTVDDAHALRAALTPGRRIVLVGAGWIGAETATVARHLGC
                     EVTVVEAAATPLAGALPAELGALMADWYAAAGVDLRCGAGVAGAADGGVLLADGTHLPA
                     DEVLVGIGAAPATDWLRGGPLVPDPDGTIPVDDRLRTALPGVLAVGDCASYPSARSGTR
                     LAVQHWDHALHSGAAAAASLLGTLDAPYDPVPYFWSEQFGRMVQYAGRHAGADHLLWRG
                     SPSDPDWTVLWLREGALVALLAVDRPRDLAQGRRLIERGGALDPARAADPAVQLKAAAR
                     "
     regulatory      14303..14415
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(14372..14385)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.18"
                     /tool="antismash"
     gene            14411..15565
                     /gene="thiO"
                     /locus_tag="OU787_RS07750"
                     /old_locus_tag="OU787_07750"
     CDS             14411..15565
                     /EC_number="1.4.3.19"
                     /GO_function="GO:0016647 - oxidoreductase activity, acting
                     on the CH-NH group of donors, oxygen as acceptor [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="thiO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007448517.1"
                     /locus_tag="OU787_RS07750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_07750"
                     /product="glycine oxidase ThiO"
                     /protein_id="WP_268658919.1"
                     /sec_met_domain="DAO (E-value: 4.6e-65, bitscore: 219.1,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPSDAPDVLVVGGGIIGLGVAWRTAQRGLSVAVVDPHPGGGAAQ
                     VAAGMLAPVTELQYGEEPLLRLGMASNERYAAFAAELTELTGLDTGYRATGTLAVALDS
                     DDRAELRELHAFHGRLGLASEWLTGRECRRLEPMLAPGVRGGLHVADDHQVDGRRLAAA
                     LVAACALAGVAFHRAEAAELLVADGRAAGVRLSTGERLAAGRTVLAAGSRSHLLPGLPD
                     GVLPAIRPVKGQVLRLRMPTAYGPFLSRNVRAVVRGQHLYLVPRADGELVVGATTEELG
                     HDTTVTAGGVYELLRDAHELVPGITELPLVETCAGLRPGSPDNAPVLGPTALAGLAAAT
                     GHYRNGVLLTPVTADLLADYLATGELPALAADFTPDRFAPKVPA"
     misc_feature    complement(14457..14472)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.03"
                     /tool="antismash"
     gene            15562..15771
                     /gene="thiS"
                     /locus_tag="OU787_RS07755"
                     /old_locus_tag="OU787_07755"
     CDS             15562..15771
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015608023.1"
                     /locus_tag="OU787_RS07755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_07755"
                     /product="sulfur carrier protein ThiS"
                     /protein_id="WP_030461016.1"
                     /transl_table=11
                     /translation="MNTVALTVNGEPRTLPATTTLDVVVAEVSAANTGVAAAVNEAVVP
                     RSSWPATTLGEGDRVEILTAVQGG"
     gene            15775..16566
                     /locus_tag="OU787_RS07760"
                     /old_locus_tag="OU787_07760"
     CDS             15775..16566
                     /EC_number="2.8.1.10"
                     /GO_function="GO:1990107 - thiazole synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135291.1"
                     /locus_tag="OU787_RS07760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_07760"
                     /product="thiazole synthase"
                     /protein_id="WP_030461015.1"
                     /transl_table=11
                     /translation="MADDALVIGGTTFDSRLIMGTGGAPSLEVLEQALRVSGTELTTVA
                     MRRVDTATQGSVLEVLARNGIRVLPNTAGCYTAGEAVLTARLAREALGTDWVKLEVIAD
                     ERTLLPDPIELLDAAETLVDDGFTVLPYTNDDPVLARKLEDVGCAAIMPLGSPIGSGLG
                     IRNPHNFQLIVEAANVPVVLDAGAGTASDVALAMELGCSAVMLASAVTRAQEPVLMAEA
                     MRKAVEAGRLAHRAGRIPRRYYAEASSPTAGLADTRERPAF"
     gene            16682..16999
                     /locus_tag="OU787_RS07765"
                     /old_locus_tag="OU787_07765"
     CDS             16682..16999
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="OU787_RS07765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="OU787_07765"
                     /product="hypothetical protein"
                     /protein_id="WP_268658920.1"
                     /transl_table=11
                     /translation="MGADSREADVLGAVLACGPVALLDGWALSQALGTRAAGLVLVLMV
                     PVLIGAGIGAGTARPGSPPSVRLLRAGIGALVAHLLLAALLLVLFALRRPADGPVPIPN
                     P"
     gene            17015..18751
                     /gene="pknB"
                     /locus_tag="OU787_RS07770"
                     /old_locus_tag="OU787_07770"
     CDS             17015..18751
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pknB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF033483.0"
                     /locus_tag="OU787_RS07770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_07770"
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="WP_268661829.1"
                     /sec_met_domain="Pkinase (E-value: 4.2e-51, bitscore:
                     172.4, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLDDPLHGVLLDGRYRVEQRIAVGGMSTVYRGTDTRLDRTVALK
                     VMHPSLAGDGEFTARFIREAKAVARLAHPNVVNVLDQGADPQAVFMAMEYVPGRNLRDV
                     LRDRGALSVRAALDVLEPVLAALGAAHRAGLVHRDVKPENVLITDTGMVKVADFGLVRV
                     LAGADSTAASTTGTGQLLGTVSYLAPEQIRQEPTDQRVDVYATGILLYEMLTGGKPHTG
                     ENAAQVMYRHLHEDVPPPSRTAPAVGPELDAIVAAATARDPQARPWDAVELLASVQRAR
                     RSLPAAQLDAEPPASTRPTPRYGPGEATAVIEKVPALERTSVLEVPPELLPPVRPVVND
                     DPPRGLPGRALRSGFGRRPLIWSAVLAVVLLLVGGVTYALSSAVYATVPSVLGQSREQA
                     SATLDGQGLHGAFSEQFSESVQAGRVISTDPGVGVRVRKSDPVKVVLSRGPERVQVPDL
                     AGRPLADATKALGGARLVAGGTTEEFSDTVPKGSVISTEPAAGAALSPNSPVALTVSQG
                     MHPVPDVGGMSKEDASKAIQDAGFVPQVAGLIPIGKVTGQSPQAGTPARQGSTVTITVS
                     LF"
     gene            complement(18762..19391)
                     /locus_tag="OU787_RS07775"
                     /old_locus_tag="OU787_07775"
     CDS             complement(18762..19391)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135294.1"
                     /locus_tag="OU787_RS07775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_07775"
                     /product="sulfite oxidase-like oxidoreductase"
                     /protein_id="WP_030461012.1"
                     /transl_table=11
                     /translation="MGQHRSEPQPPTDPRLPPGQRPQRGWPVLHYGPVPRFKPESWDFQ
                     VFGATADAEKASWDFTAFHALPKTTVRGDFHCVTKFSMLGNEWTGVAARTVLDLVPPDP
                     AVTHVMVWAEYGYSANLRLADFADPATVFATHHDGRPLTLEHGFPVRLVVPHLYAWKGP
                     KWVRAVEYMRADRRGFWEERGYHNLADPWREQRYSYQEQPGDGPLR"
     gene            19690..20172
                     /gene="bfr"
                     /locus_tag="OU787_RS07780"
                     /old_locus_tag="OU787_07780"
     CDS             19690..20172
                     /EC_number="1.16.3.1"
                     /GO_function="GO:0004322 - ferroxidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0008199 - ferric iron binding [Evidence
                     IEA]"
                     /GO_process="GO:0006880 - intracellular sequestering of
                     iron ion [Evidence IEA]"
                     /codon_start=1
                     /gene="bfr"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019433713.1"
                     /locus_tag="OU787_RS07780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_07780"
                     /product="bacterioferritin"
                     /protein_id="WP_030461011.1"
                     /transl_table=11
                     /translation="MQGDPEVIEFLNEQLTAELTAINQYFLHAKMQENFGWTKLAKYTR
                     HESFDEMKHAEVLTDRILFLDGLPNYQRLFHVRIGQTVKEMFEADRQVEVEAIDRLRRG
                     IVVMRAKNDVTSANIFESILADEEHHIDYLDTQLELLDKLGEALYIAQLIEQPESS"
     gene            complement(20215..20463)
                     /locus_tag="OU787_RS07785"
                     /old_locus_tag="OU787_07785"
     CDS             complement(20215..20463)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer2_BFD"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135296.1"
                     /locus_tag="OU787_RS07785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_07785"
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_030461010.1"
                     /sec_met_domain="Fer2_BFD (E-value: 2.7e-13, bitscore:
                     48.7, seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYVCMCHAVTEAQVKQKIDEGASTPRQIAQGCRAGTDCGSCVRRI
                     QALLGEHGARPCPTARLAERLGLADPGAAPEGAPRAA"
     misc_feature    complement(20623..20637)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.35"
                     /tool="antismash"
     misc_feature    21070..21083
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 17.7"
                     /tool="antismash"
ORIGIN
        1 ctgaccgtcg tcccgcaggt ccaggacctg ccgccggtcc ggctgcccgg cgagtccggc
       61 gggcagggcg agtccaacac ccacaccctg gcgctggccg gcgacgacga cgtcatcccg
      121 cgcgagtacc ggcacggcga cgacctgcgc cgggtgcact ggaagtccac cgcccggtac
      181 ggcgagctga tggtccgccg ggaggagcag ccgctgcagg cccgcgccac cgtgctgctg
      241 gacacccggg agaccgcgca ccgcggctcc ggcccggcgt cctcgttcga gtgggcggtg
      301 tcctgcgccg cctcggtcgc cgtcgacctg gtgcagcgcg gctaccgcac ccggctgctc
      361 accgacaccg gcttctcggt gcccgacccc ggcaccggcg gcaccggggc cggggcggcc
      421 gaggcggtcg ggatgctgct ggacgcgctg gccgtggtcg agcactccga cggcggcacc
      481 ctggcccggg ccgaggaggt gctccggctc ggcggcgagg gcctgctggt ggcggtggtc
      541 ggcgacctcg acgaggagca ggccgagcgg ctggcccggc tgcgccgccg caccggcggc
      601 gccgtcgccc tgctgctgga caccggcacc tggtccgggc tgcggctcct gctgccggac
      661 acccccgacg aggaggccgc cgcccgggtc gcccggctgc gcgagtccgg ctggacggtg
      721 ctgccggtgc gggccggcga ctcgctgccc gccctgtggc gggccgcgga ccgcacccag
      781 aacaccaccg ttccctaccg agacgaggtc ggcgcgtgac cacccgggcc aagttgacgc
      841 tctgcgcggc cctggcgacc gccctggcgg cgctgtgcct gtccccgctg ttccgggact
      901 ccttcgcgct ggccccgcac ggcctgctga tgatcgccgt cacggccggc gccggcgccg
      961 ggctgcgcgc cctgccgctg ccccgggccc tggtgacgcc gctgcagctg ctcgtggtgc
     1021 tgtacgtgct gatgctcacc accgtgcagt ccgcgatgag cttcggcgtg ctgcccggcc
     1081 cgggcgccct ggacgccgtc tccaccctgc tgagcagcgg cggcaccgac atccaggagt
     1141 acgcgatccc cgccccggcc accgacggcc tgcggctgat cgtggtcggc gcgatcgccc
     1201 tggtcgccgt gctggtcgac gcgctggcgg tcacctaccg ccgggccgcc gccgcgggcc
     1261 tgccgctgct cgccctgtac tcggtggccg gcggcctggt cgactccccc ggcggcatgt
     1321 ggctgtggtt cctgttcggc gcggcgggct tcctggccct gctgtacacc gagggccagg
     1381 accggctcac ccgctggggc cgggtcttcc acggcaccgg ccgctcggcc gtgacgctct
     1441 ccaacggcgg ccgccggatc ggcgtgatcg cgctggccgc cgccctgctg ctgccggtgt
     1501 tcgcccccgc ggtcggcccc ggcctgttcg gcagcgtcgg cggccacagc ggcgagggcg
     1561 gcggcaacgg gaacggcaag ggcgacgagc gctcgctcaa cctggtcgtc gcgctcaccg
     1621 ccaacctgcg ctccagcgac gacaccccgc tgctgagctt ctccaccgac tcgcccgacg
     1681 ccgaccagct ctacctgcgg atcgccgcgc tcagcgagtt caacggccag gagtggctgc
     1741 ccggcgagca gaacgcccag ccgctgcccg ccaccgtgcc cgcccccgag ggcctcgcgc
     1801 cgaacctccc caccaccacg gtccgcacca aggtcaccgt caccgagcag ctcagcaccg
     1861 cctggctgcc gatgccgtac ccgatgtcct ggctggaggt gccgaacacc gggaactggc
     1921 gcttcgaccc ggccggacgc accgtcagcg gcgccaacgg ccagaagagc aagggcctga
     1981 cgtactcggt cggctcggtc gcggtcaacg ccacccccgc ccagctgcgc gcggccggcc
     2041 cggcccccga ggacatcacc aagcgctacc tgggcctgcc gtccaacctg ccgcccgtgg
     2101 tcgccgagac cgccaaggac gtcaccaagg gcaagagcac cccgtacgac caggcggtcg
     2161 ccctccagca gtacttcacc agcggcggct tcacctacaa caccaagatc gaggcccgca
     2221 ccgggccgga cgccatcgcc aagttcctcc aggacaagga gggcttctgc gtccacttcg
     2281 ccgccaccat ggccgcgatg tcccgctcgc tgggcatccc ggcccgggtc gccatcggct
     2341 tcaccccggg caccggcaac ggcaccgacc gggtggtgcg cagctccaac taccacgcct
     2401 ggcccgagct gtacttcgac ggctacggct ggatgcgctt cgagccgacc ccgaaccggg
     2461 gcagcacccc gctctactcc gtccagcaga ccacgcccac cagcgcgccc agcaccgccc
     2521 cgagcagcgc cgcgccgagc gaccagccct ccgcccagcc gtcctcctcc agcagctgcc
     2581 ccccgcagca gcaccggatc ggcgactgcg ccgacgagca ggcccaggcc gcccaccagg
     2641 gcgacagcac ctcgtggtgg ctgtcctggc cgggcctggt caccgtgctc gccgtcctgc
     2701 tgctgctggc cgcgctggcc ttcccgctgc tctggcgcac caggctgcgc cgccgccgcc
     2761 tcggcgccgg ccgccacctg tccggcgcgg acgggccgcg gctcaccgac gagcaggtgc
     2821 tcgccgcctg ggccgaactc gtcgactccg cctgggacct gggcatcccg ccggacgagg
     2881 cccgcacccc ccgcaacgcc gcccgacggc tcgccgagga cgccggactc gacgccgacg
     2941 ccgcggccgc cgcgggccgg gtcgcgctgg ccaccgagcg ggtcatgtac gcccgcgagt
     3001 ccgaggcgcc cgcgcacctc ggcggggacg tccgcaccgc ccggcaggcg ctgctggtcc
     3061 gcgccacccg cacccgccgg ctgcgcgccc tgctgctgcc cgcctccgcg gtccgcctct
     3121 ggtggcgcgc ccaggaccgg gccgccgccc gccgggagcg caccgccgag cgggcggccg
     3181 cggtgcgggc cgcgctggcc gggccgttcc ggcggcggaa gaaggagcag gagtgagacc
     3241 ccgccccgcc gggtgaccac cggggaacgc ggggcccggc cggggccccg ggcgccttgg
     3301 gtgccccggg ctccctgggc tccccgagcg ccctgggcgc acacgaaaga tccgcccggc
     3361 ggagggtttc ccctcgccgg gcggatcacg tctcggtggg tgctgctaca gcccgctctg
     3421 ctcgtcgcgg cgccgctgcc agcgctgttc catacggtcc atgacgccgg tccgccggcg
     3481 tggcgctgcc gcctgccgtg ggccgggccc ggccgggccg cgccgccacg cggtgaccgc
     3541 gaggaccgca caaccaagca tcaccaggaa cccgaccaca ctgacccaga tgacctgcgt
     3601 gaccaggccg cccatgagca gcgcgacgcc cgccacgaac cccgccacgg ccaggtagac
     3661 ccgccgacgg gtgtaggtgt gcaggccggt tccctcgagc gctgacgcga acttgggatc
     3721 ttcggcgtac agcgctcgct ccatctgctc gagcagtcgc tgctcgtgct ccgagagcgg
     3781 cacggagtcc tcctactcgt cggtcgcggg gcgaccggtc cgccacccct ggctcgggcc
     3841 tgtgtggtcc atatgcccca ccggtctggc cgtcatgctt accggcttta cccagatcat
     3901 acggtccacg gccctggttc ggcgtggtca atcaggcgtg gctcgggcca cctcggcggt
     3961 ggtcccaccc gtgcaacgag cggggggccc gcttggtgcc ccccgccggg ggtcagatcg
     4021 cctcggcgag caggtgcagc tgggtggcga cggcgtggaa agcgggctgt tcggcggccg
     4081 cgagctcgag cttgagcagg gcgtcgagcg cgccgggctc ggtgtcgacc agcacgccgg
     4141 ggacgaggtc ggcgaagacc cggatgccgt gcacggaggt gacccgcagc ccggcgccgg
     4201 cggccagggc gtccagctgc tcgccggtga agcggcgggg catcgggtcg ccggcgcccc
     4261 agcggccgtc ggcggcgtcc agcgcggtgc gggcctcggt gaactggccg gccaccgcac
     4321 gggccagcac ggcgccgttg cggttggcgg cgagcaggct gaccaggccg cccccgccga
     4381 gggtgccgac caggttgccg agcgcctcgg cggggtcgtc gacgacctcc aggacgccgt
     4441 ggcagagcac cgcgtcgacc gatccggccg ggacgaggtc gggcagcgtc tgagtgtcgc
     4501 cctggacggc ccggaccagc tcggtgacgc ccgcctcggc ggcccggcgc tccagcgcga
     4561 acagcgcgtc ggggctcggg tcgaccaccg tcacccggtg gcccagccgg gccaccggca
     4621 ccgcgaagtt gccggtgccg ccgccggtgt cgacgacctc caggaccggc cgtccgagct
     4681 cggcggagcg ccgctccagc gcctcccgca gcacctccca caccacggcg gtacgcagcg
     4741 cactgcgggg acgagtcgga tacaaggcgg cacccctctt ggcaggttct tccacggcgg
     4801 tcttccacgc cgggaacggc tcccagctta tccgccgggg ccggacggct ccggcgcggc
     4861 gcagccgccg cggccgccgg gcgctgcggt caggggtgca gggccaggat ccgctccacg
     4921 atgcgcaggt acagggcggt gttgcggatc aggtcgtccg cgtcccgcgg cccggcggcg
     4981 ccggcgatgc ccgcctcggc ggcggcccgg cggcgggcgc cggccgcgaa gtaggcggcc
     5041 cactcggcga gttcgggggc gacctcgggc agcagctccc aggccgggcg gatcgcctgg
     5101 cggcggcgcg ggtggcgcac cgggcggccg cggacggcga gcacggcggc ggtggcgcgc
     5161 agcgcggcga ggtgtgcggt ggcgtagcgc tccagcgggt cctgtcggcc ccgggcgtgc
     5221 accagggtgc ggtgcgcgtg ccggagcagt tcgagcgcgg cgggcgaggc cgagctgcgg
     5281 cgcagcaccg ggtgcgcgtc cccgccgcgg ccggccggca gggtgggctg ctcgacggcg
     5341 ggccgcccgg ggtcgggccg cccggcggcg ggtcggtcgg cggcggattg atcgacggca
     5401 gggcgggcga caggctcagg acggctgatg gtcatgggtc tcccccgttc actccggacc
     5461 tttgcccgga ccggtcggtc cgcgcatgca tccatcgtga acggggggtc tgacaactcg
     5521 gagtcccccg actccgcggg gtcccccgac cccgtcccgt cgtccccgtc cggccggatc
     5581 cccaggatcc ccccccgggg gagggagggc cgggctccgc cgccccgtgt cggcggtgcc
     5641 cggccctccc gctccggccg ctggtcgcgc tccgggcctg tggtgcgggc cgtcgttccc
     5701 ccggaccggc ggcctgccca gagcgctccc gggtggctcc gcccggcggc ggccttcccg
     5761 gtgcgcacta ctctgccgcc gggcgggagc ggtgggtatc cgtgcgggta ctcaaccggc
     5821 gatctgagta cggatactca gtccgcccgg tcggcctccc ctcccgggcc gtcggccggg
     5881 ccgggtacgg tggccgcgtc ccgtccgagg tccgggcggg tacggggagg gggccgcggt
     5941 gggagccgtt ccgctgatct tcaccagcgg ctgggcgagc gggatcaacg cctacgccgt
     6001 ggtgctgctg ctgggcctgt tcggccgctt cggcggggcc gactcggtgc cgccggtgct
     6061 ggagcgcacc gacgtgctcg tcgccgccgg ggtgctgttc ctgtgcgagg cggtgctgga
     6121 caagatccct tacgtggaca gcgtctggga cgtcgtccac accttcgtcc ggccggtcgc
     6181 gggcgcgacg gtgggcgccc tgctggccgc ccacgacccg ggctcgctcg gcgaggtcgc
     6241 ggccggggcc ctcggcggca ccaccgccct ggtcagccac ggcgtcaagg cgggcctgcg
     6301 gatggccgcc aacacctcgc ccgagcccgc ctccaacatc ctgctcagcc tcgccgagga
     6361 cctctcggtc gcgggcctgg tcaccctggc gatcttccac ccctggctgg ccgcgtccac
     6421 cgccgcggtg ctgctcgccc tcggcgtgct ggtggtctgg ttcgcggtct cccggatccg
     6481 ccgcttctgg ctccgccgcc gggagcgccg gctggcccgc gccgccgcgg cggcctgagg
     6541 ccgggaccgg ggcccggccc gggggcgcat aggatctgct gccatggctc ggatcatcgt
     6601 cgtcggtgca ggcatgggcg gactggccgc cgcttcgcgg ttgggcacgc tcgggcaccg
     6661 ggtgacggtg ctggaggccg ccgggacgca cggggggcag gtcggggcgt accggcggga
     6721 cgggttcggg ttcaacaccg ggccggggct gctcgcgctg cccgccgtct accgggacct
     6781 ggcgctgaag accgggcggg agccgttgga gcagctggtc gggctgcggc cggtcgaccc
     6841 ggagagccgg cacctgttcc cggacgggac ggaactgctg ctgccgaacg cctcccgggg
     6901 cggggtgggc caggcactgg acgcggcgtt cggcgcgggg acgggcgccc gctggggcga
     6961 actgctcaac cgggggcgga cggtgtggga ggccacccgg cgcccgctgc tggaggagcc
     7021 gcgcccggcc gccgacccgg cggacccgta cccggtgccg ccgcggcgcg ggctgtcccg
     7081 gctgctgccg cgcgggcggc acaccctggc cgacgcggcc cgggagctgg gcggcggccc
     7141 gggcccggcc gcgctgctgg gcgagtacgc gctgcggtac ggcctggacc cgcggtccgc
     7201 gcccgcctcg gcgacggtgc tgccgtacat ggagcagtcg ttcggcgtct ggtacgtgga
     7261 cggcgggctg cgggcgctgg ccgacgcggt gttcgagcgg tgcgggaagc gcggggtgga
     7321 gttccggttc gacaccccgg tgcgggccct ggagcaggac ggcgaccggg tggtcggcgt
     7381 ccgcaccgac cagggggtgc tggccgcgga cgcggtgctc tccgccgtcc ccggcctggg
     7441 ggtggccgag cccgccgcgc ccgcgccggg ccggttcacg gtgctgctcg cgctggacgg
     7501 cgcccgcccg gccggcaccg cgcaccgcac cgtggtgcac gccgcggacc cggcggccga
     7561 ggcccgcgcg gtgttcgccg gacgggcgct gccggaccgg ccgaccgtgc aggtgctgcg
     7621 cccggacgac ccggcgctgg tgcccggccc ggacgcggag gcggccgtgc tgaccgtcac
     7681 ggtgcccgcc ggactcaccc tctccgacgc cgaacgggac gcctacgccg ggcggttgct
     7741 cgaccacctg gccgccgcgg gcctggacct gcgcccccgg gtgcgctggc gggagacccg
     7801 gctgaccgcc tcggtgccgg tgccctcgct ggccggcggc cacctcgccc aggccaaccg
     7861 gccgggcccg gcgggcctgt acctgatcgg cgcgcacgcc cacccgggcg gcgggctggc
     7921 ccgggtcggg atgtccgcct cgatcaccgc cgggctgatc ggcccggcct gacggggcgt
     7981 cagtactgct gctggtagta ccagttctgg tccggcgact gctgctgcga ctgctgctgg
     8041 ggctgcggct gctgcgggat ccagggctgc tggtactgct gctgggtgta cgggtcctgg
     8101 tagaccggct gcccgtactg gtcgtagccg atcagctgca actgcggctg ctgctccggc
     8161 tgttgctgga actgcggctg ctggaactgc ggttggtact gctgctggta ctgctgctgg
     8221 tcggcccact gctcctgctg ggcgtagccg tggtcctgct gctggtagcc gtactcctgc
     8281 ggcgcctgct gggcgtactg cggctgctgc gggacctggt aggcgttcgg gtcgtcggcg
     8341 tagacgcccg cgtcgagctg ctggaactcc tcgtagccgg ccgagcggtc gtcgaacggg
     8401 tcggcggact cgtcctcgat cgggccgacc tcgccgaccg gggcgaccgg ttccggctcg
     8461 gccgcggcgg cggccgtcgc gccggtggcg gcggccagca gcgggacctt cgccagcggg
     8521 ccgggcaggg cgccgtcggg gcggcgcagc gaccagccga ccgggcggcc gcgcttgacc
     8581 gagccggtca ccagcacctg gccgagtccg aacgcggcgg cgcccgccgc tatcaccggc
     8641 agcgaggagg tgcgcatccc ggcgaccacg ccgaggaagc cgagcagcgc gagcgcccgc
     8701 cagtgcagcg gggcccggtg ctggagcagg agttcggcgg tcagccagag cgcgaccagg
     8761 gccagcgcgc cgtagaggag caggtacccg aagctcatcc cgcaacctcc agacgccacc
     8821 atcaccgcgc ggttgcgggc gactgtacag cctccgggcg aacagcaccg catcccggac
     8881 cgggccgtcc gcgcggcccg tgctcagcgg gtgtgcaggc ccaggttctg gtagatctcc
     8941 agcgtcgagg tggagtggtt gagggtgatg aagtgcagac cgggggcgcc ctccgcgagg
     9001 aggcgctcgg ccatcgcggt ggcgtgctcc aggcccgccg cgcggaccgc gaccgggtcg
     9061 tcggcgacgg actccagctt gcgccggaag tcgggcggga agtcggagcc ggacagctgc
     9121 gggaagcgca ccagctggcg gatgttggtg accggcatga tctccgggat gatcggggtg
     9181 tcgcagccgg ccgcggcgac ccggtcgcgc agccgcaggt agtcctcgac ctcgaagaac
     9241 atctgggtga tcgcgtagtc cgcgccggcc cggcacttgg cgacgaagtg ccggatgtcc
     9301 tcgtcccagt tctccgaacg cgggtgcatc tgtgggaacg ccgcgacgcc cacgcagaag
     9361 tcgccgatgt ccttgatcag tccgaccagt tcggcggcgt agctgacgcc ctcggggtgg
     9421 cgcacccact cgcccatcgg gtcgccgggc gggtcgccgc ggaccgcgag cacgttgcgc
     9481 acgttctggt cggcgtactg gccgatgatg ttgcgcagtt cggccaccga gtggtcgacg
     9541 gcggtgaggt gggcgaccgg ggtcagggtg gtctcggtgg cgatccggcc gaccaggtcg
     9601 acggtgcggc cgcgcgagga gccgccggcg ccgtacgtca tgcagacgaa gttcggttcc
     9661 aggcactcga cccggcggat cgcgtcccag agcttgcgct cgccctcgtc gttgcgcggc
     9721 ggcatgaact cgaaggagaa ggagcggtcg cctgccgcca gcaggtcgcg cacggtctgt
     9781 gcgcggtcgc ttctggtgga gggaatgccg agtgccatgc aggcaggtta gccgtcggcg
     9841 gcgcggcccg gacaaacgac gtccagcaat tgagacacca tgtgagattt ccggccgcgg
     9901 gccgggccgc cccgcgcgcg ccgggcccgg cctcggtgga acggggcacc cgaccgcgca
     9961 cgttaatctg actgtcagcc ccctcgatcc ggagttccag gtgcccccct ccatccgcct
    10021 tccccgcaac cccgtcgacg cggaggacgt gcgcgagcgc gtgaacacca ccctcggcgc
    10081 gttcatggcc gagcgggccg ccctgctctc cggcatctcc gacgacctcg gcccggtcgc
    10141 cgacgccctg cgcgacttcc tgctcgacgg cggcaagcgg ctgcgccccg cgttctgcta
    10201 ctggggctgg cgggcggccg gcggcgccga tgacgaaccc ggcatcgaac gggccgccgc
    10261 cgcactggaa ctgctgcagg ccagcgccct ggtccacgac gacctgatgg accgcagcga
    10321 cacccgccgc ggcctgcccg ccgtccaccg ccgtttcgag aacctgcacc gggccggcgg
    10381 ctggcgcggc gaccgcgaac agtacggggc gagcgcggcg gtcctgctcg gcgacctgct
    10441 gctgatctgg tgcgacgaac tgttccagcg ctccgggctg ccggtcgccg ccgtctcggc
    10501 cgccaagccc gccttcgacc tgatgcgcac cgaggtcatg ctcggccagt acctggacgt
    10561 gctggagccg gtcgcgggcg actccaccga cgccggcgcg atcgaccggg cccgcaccgt
    10621 cctgcactac aagtccgcga agtacaccat cgaacgcccg ctccaggtcg gcgcgctgct
    10681 ggccggcgcc ggacccgacc tggtcgacgc cctcggctgc ttcggcctgc cgctcggcga
    10741 ggcgttccag ctccgcgacg acctgctcgg cgtcttcggc gaccccgccg tcaccggcaa
    10801 gcccgccggc gacgacctgc gcgagggcaa gcgcaccctg ctcgtcgccc acgccatgcg
    10861 cagcctgtgc ccggccgacg ccgcccgcct ggacgcccgg ctcggcgccc ccggcctgga
    10921 cgccggcgag atcgccgccc tgcgcgacct gatcacccgc agcggcgccc ccgaactcgt
    10981 cgaggcccgg atcgacgccc tgctcgccga ggccctgacc gccctcgacg ccgccccgat
    11041 cgccgacggc ccgacccgcg aagtgctccg ggcgctggcc gacgccgcca ccgtccgcaa
    11101 gtactgacgg gccgtcagga agcccggcgc cgccaccagc ggcgcgaggc cagcgccgcc
    11161 agcgccgccc cgaccgcgtt cagcagcacg tcgtccaccg aggagacccg gtccagccgc
    11221 agcacgtact gggccgtctc caccagcacc gaacccgccg cccccagcgc cagcacccgc
    11281 cgcaccgagg ccagcgccgc gaaccgcagc ggcgccagga acccgaacgc cgcgaacacc
    11341 agcatgttgc cgacgatctg cgccaccgcg gtcgccggcg gcccggcgcc gacgatctcc
    11401 gcgatgtcgt gcagcggcac caggttcacc cggcggcgcg gaccgcccgg gtcgacgccc
    11461 ggcagcagga tcatccacac ccacggcacc gtcccgtaga ccatgccgac ctcggccagc
    11521 gccgaacgcc gcgcccaccc cgccgccacc ccggccgccc ggcggcgacg ggccagcgcc
    11581 cacaccgcca gcaccgccac cggcagcgcg gccgccgcca ggaacacgat cccgttgacc
    11641 gtccccaccc agccgttcca cccggcgtgg tcaccgagcg gccgctgggc gaggaacgcg
    11701 acggcggcgg cgccgagcag cgccggcacg aggagcgcca cccggcgggc gcgacgggcg
    11761 gcggacaggg tctgatccat gcctgcacgg agtaccgccc ggccccgccc ggttcccgcc
    11821 cgggaccgga tcttccccgg ctgccctccg ctccgcggtt cccgaccggg gacggggctt
    11881 tcctcttgga ccggatcttc ccccgactgc ccttccgccc cgcgcagttc cccgcgcccc
    11941 tgacggggct cggggcgcgg gagttgacag gggcggggag cggtcgggcc ggaaggccct
    12001 agcggaggcg ggccgccagg gcggttgcgg cggcgcgggg gtcttcggcg gcggtgaggg
    12061 cgcggacgac gacgatgcgg gtggcgccgg cggccaggac ctggtcgagg ttgccggcgt
    12121 cgatgccgcc gatggcgaac caggggcggt cggggcggcg ggcggcggcg tggcggacca
    12181 ggtcgaggcc gggcgcgtgg cggccgggct tggtgggggt gggccagacc gggccggtgc
    12241 agaagtagtc gacgccgggt tcggtgagcg cggtgtcgac ctcggtctcg ctgtggcagg
    12301 agcggccgat cagcacgtcc tcgccgagga tgcggcgggc gacggcgacc ggcaggtcgt
    12361 cctggccgag gtgcagcacg tcggggcggg ccccgtacgc gacgtcggcg cggtcgttga
    12421 cggcgagcag cttgccgtgg cgccgggcgg cgtcggcgaa gacctccagg tgctccagct
    12481 cctgcttggc ctccaggccc ttgtcgcgga gctggacgat gtcgacgccg ccgctgagca
    12541 ccgcgtccag gaactcgggc aggtcgccct gttcgcggcg ggcgtcggtg cagaggtaga
    12601 gccgggcgtc ggccaggcgc tgccgggcgg tgggtgcggc ggtcacaggg ccatggcctg
    12661 ggcgcggcgc ttgacctcgg tgccgcggtt ctcgcgcagg gcctggatcg ggctgccggg
    12721 cagggagtcg tcctcggtga acatccactc gaggatctcc tggtcggaga agccgcagtc
    12781 gcgcagcacg gtgagggtgc cggccaggtg cttgaccagg ccgtcgtcct cgatgaagtc
    12841 ggcggggacc tgcagggagt tgttggggcc gcggcggacg gccagcaggg tgcggttctt
    12901 caccatggcg cggacctcgg tgatcaccac gccccaccgc tccgagatgt cgggcaggta
    12961 cagccacgcg gggaccaggg cgtcaatctt gggatcaatc tcgctcactc ccccagccta
    13021 ggcgctaccg ggccgccgcc ttcaactgga cggccgggtc ggcggcccgg gccgggtcga
    13081 gtgcgccgcc gcgttcgatc aggcggcggc cctgggccag gtcgcgcggc cggtcgacgg
    13141 cgagcagcgc gacgagtgcg ccctcgcgca gccagagcac cgtccagtcg gggtcggacg
    13201 gggagccgcg ccacagcagg tggtcggccc cggcgtgccg gccggcgtac tggaccatgc
    13261 ggccgaactg ctcggaccag aagtagggga cggggtcgta gggggcgtcc agggtgccga
    13321 gcagcgaggc cgcggcggcg gcgccggagt gcagggcgtg gtcccagtgc tggacggcga
    13381 gccgggtgcc ggagcgggcg gaggggtagg aggcgcagtc gccgaccgcg aggacgccgg
    13441 gcagggcggt gcgcagccgg tcgtcgaccg ggatcgtgcc gtcggggtcg gggacgagcg
    13501 ggccgccgcg cagccagtcg gtggcggggg cggcgccgat gccgaccagg acctcgtcgg
    13561 cgggcaggtg ggtgccgtcg gcgagcagca ccccgccgtc ggcggctccg gcgacgccgg
    13621 cgccgcagcg caggtcgacg ccggcggcgg cgtaccagtc ggccatcagg gcgccgagtt
    13681 cggcgggcag ggcgccggcc agcggggtgg cggcggcttc gacgacggtg acctcgcagc
    13741 cgaggtggcg ggccacggtg gcggtctcgg cgccgatcca gccggcgccg accagcacga
    13801 tccggcggcc gggggtgagg gcggcgcgca gcgcgtgggc gtcgtcgacg gtgcgcaggg
    13861 tccgggcgcc gggcaggccg gggagggtgc ggggtgcggc gccggtggcg atcaccaggg
    13921 cgtcgtacgg gagttcgccg cggtcggtgt gcaggacgcc gtcggccagg ccggtggcgc
    13981 ggcggccggt gagcaggtcg acgccgaggc cgtgccagtc gatctcgaag gcggtggcgt
    14041 cggtcttgcc gagcagcacg tccttggaga gcgggggccg gtcgtagggg aggtggagtt
    14101 ccgcgccgac cagggcgagc gggccgttcc agccgccctg ccgcaggttg agggcggtct
    14161 gggcgcccgc catgcccgcg ccgaccacga cgacccggtc cgttgccttc agctcagcca
    14221 ccacggcgtc caccctactc accggcgccg tccaccctgc gtacgcgcct tcgggcggcg
    14281 gcgggggcgg cgttaaggtg gggggtactt acacgggagc ccggtgcacc gggctgagag
    14341 gcgggctgtg gcggcccgcg accgtccgaa cctgatccgg gtcatgccgg cgaagggaga
    14401 atcagcggct gtggcacctt ccgacgcgcc tgacgtgctg gtggtcggcg gcggcatcat
    14461 cggtctcggc gtggcctggc gcaccgcgca gcgcggcctg tccgtcgcgg tggtcgaccc
    14521 gcacccgggt ggcggtgcgg cgcaggtcgc cgcgggcatg ctcgcccccg tcaccgaact
    14581 gcagtacggc gaggagccgt tgctgcggct ggggatggcg tcgaacgagc ggtacgccgc
    14641 gttcgccgcc gaactgaccg aactgaccgg gctggacacc ggctaccggg ccaccggcac
    14701 gctggcggtg gcgctggact ccgacgaccg cgcggagctg cgcgaactgc acgccttcca
    14761 cggccggttg ggcctggcct cggagtggct gaccggccgc gagtgccgcc ggctggagcc
    14821 gatgctggcg ccgggcgtgc gcggcgggct gcacgtcgcc gacgaccacc aggtggacgg
    14881 gcgccggctg gccgccgcgc tggtcgccgc ctgcgcgctg gcgggcgtgg ccttccaccg
    14941 ggcggaggcc gccgagctgc tggtggcgga cggccgggcc gccggcgtgc ggctgtcgac
    15001 cggcgagcgg ctggcggcgg ggcgcacggt gctggccgcc ggttcgcgca gccacctgct
    15061 gccgggcctg ccggacgggg tgctgccggc gatccgcccg gtcaaggggc aggtgctgcg
    15121 gctgcggatg cccaccgcgt acgggccgtt cctgtcccgg aacgtgcggg cggtggtgcg
    15181 cgggcagcac ctgtacctgg tgccgcgggc cgacggcgag ctggtggtcg gcgcgaccac
    15241 cgaggagctg ggccacgaca ccaccgtcac cgcgggcggc gtctacgagc tgctccgcga
    15301 cgcgcacgaa ctggtgcccg gcatcaccga gttgccgctg gtggagacct gcgcgggcct
    15361 gcgtccgggc tcccccgaca acgctccggt gctgggcccg accgcgctgg ccggcctggc
    15421 cgccgccacc gggcactacc gcaacggcgt gctgctcacc ccggtcaccg ccgacctgct
    15481 cgccgactac ctggccaccg gcgaactgcc cgccctggca gccgacttca cccctgaccg
    15541 cttcgccccg aaggtccccg catgaacacc gtcgccctga ccgtcaacgg cgagccgcgc
    15601 accctgcccg ccaccaccac gctggacgtg gtggtcgccg aggtgtcggc cgccaacacc
    15661 ggcgtcgccg ccgccgtcaa cgaggccgtg gtgccccgca gttcgtggcc cgccacgacc
    15721 ctcggcgagg gcgaccgggt cgagatcctc accgccgtcc agggaggctg aaccatggcg
    15781 gacgacgcac tcgtcatcgg cgggaccacc ttcgactccc gcctgatcat gggcaccggc
    15841 ggcgccccca gcctggaggt gctggagcag gcgctgcggg tctccggcac cgagctgacc
    15901 acggtggcga tgcgccgggt cgacaccgcc acccagggct cggtcctgga ggtgctggcc
    15961 cgcaacggca tccgggtgct gcccaacacc gcgggctgct acaccgcggg cgaggcggtg
    16021 ctgaccgccc ggctggcccg cgaggcgctc ggcaccgact gggtgaagct ggaggtgatc
    16081 gccgacgagc ggaccctgct gcccgacccg atcgaactgc tggacgccgc cgagacgctg
    16141 gtcgacgacg gcttcaccgt gctgccgtac accaacgacg acccggtgct ggcccgcaag
    16201 ctggaggacg tgggctgcgc ggcgatcatg ccgctgggct cgccgatcgg ctccggcctg
    16261 ggcatccgca acccgcacaa cttccagctg atcgtcgagg cggcgaacgt cccggtggtg
    16321 ctggacgcgg gcgcgggcac cgccagcgac gtcgcgctgg cgatggaact cggctgctcc
    16381 gccgtcatgc tggcctccgc ggtgacccgc gcccaggagc cggtgctgat ggcggaggcg
    16441 atgcgcaagg ccgtcgaggc gggccggctg gcccaccgcg cgggccggat cccgcgccgc
    16501 tactacgccg aggcgtcctc ccccaccgcg ggcctggccg acacccgcga gcgccccgcg
    16561 ttctgacgcc cccggccgcc gcgtgtcccg gttcgggaac ggttcgcccg gcggccgtgc
    16621 ccggaccgcg ggcgggctgc cagcatggca gcaccgtacg ggaaccgggg gggatctcat
    16681 ggtgggggcg gacagccgcg aggcggacgt gctgggcgcg gtgctggcct gcggcccggt
    16741 ggcgctgctc gacggctggg cgctgtccca ggccctgggc acccgggcgg cggggctggt
    16801 cctggtgctg atggtcccgg tgctgatcgg cgccgggatc ggtgcgggca ccgcgcggcc
    16861 gggctcgccg ccctcggtgc ggctgctgcg ggccgggatc ggcgccctgg tcgcgcacct
    16921 gctgctggcc gccctgctgc tggtgctgtt cgcgctgcgc cgccccgccg acgggcccgt
    16981 cccgataccg aacccctaga ctcctcaggt ggacatgacc ctcgacgacc ccctgcacgg
    17041 cgtgctgctc gacggccgct accgggtcga gcagcggatc gcggtgggcg gcatgtcgac
    17101 cgtctaccgg ggcaccgaca cccggctgga ccgcaccgtg gcgctgaagg tgatgcaccc
    17161 ctccctggcg ggggacggcg agttcacggc ccgcttcatc cgggaggcga aggcggtggc
    17221 ccgactcgcg cacccgaacg tggtgaacgt gctggaccag ggcgccgacc cgcaggcggt
    17281 gttcatggcg atggagtacg tccccggccg caacctgcgc gacgtgctgc gcgaccgcgg
    17341 cgcgctgtcg gtgcgggccg cgctggacgt gctggagccg gtgctggcgg cgctcggcgc
    17401 ggcgcaccgg gccgggctgg tgcaccggga cgtcaagccg gagaacgtgc tgatcaccga
    17461 caccggcatg gtgaaggtcg ccgacttcgg cctggtccgg gtgctggcgg gcgccgactc
    17521 gacggccgcc tcgaccaccg ggaccgggca gctgctgggc accgtctcct acctggcgcc
    17581 ggagcagatc cgccaggagc ccaccgacca gcgggtggac gtctacgcga cgggcatcct
    17641 gctgtacgag atgctgaccg gcggcaagcc gcacaccggg gagaacgccg cccaggtgat
    17701 gtaccggcac ctgcacgagg acgtcccgcc gccgtcccgg accgcccccg cggtgggccc
    17761 ggagctggac gcgatagtgg ccgccgcgac cgcccgcgac ccgcaggccc gcccgtggga
    17821 cgcggtggag ctgctggcct cggtgcagcg ggcccgccgc tcgctgcccg ccgcgcagct
    17881 ggacgccgag ccgcccgcct cgacccggcc caccccgcgc tacggcccgg gcgaggccac
    17941 cgccgtgatc gagaaggtcc cggcactgga gcgcaccagc gtgctggagg tcccgccgga
    18001 actgctgccg ccggtgcgcc cggtggtgaa cgacgacccg ccgcgcggcc tgcccggccg
    18061 ggccctgcgc tcgggcttcg gccgccgccc gctgatctgg tcggcggtgc tggcggtggt
    18121 gctgctgctg gtcggcgggg tgacgtacgc gctgtccagc gcggtgtacg cgacggtgcc
    18181 gagcgtgctg gggcagagcc gggagcaggc gtcggcgacg ctggacgggc agggcctgca
    18241 cggggcgttc agcgagcagt tcagcgagtc ggtgcaggcc ggccgggtga tctccaccga
    18301 cccgggggtg ggcgtccggg tccgcaagag cgacccggtg aaggtggtgc tctcgcgcgg
    18361 cccggagcgg gtccaggtcc cggacctggc gggccgtccg ctggcggacg ccaccaaggc
    18421 gctgggcggg gcccggctgg tggcgggcgg gaccaccgag gagttcagcg acaccgtgcc
    18481 gaagggctcg gtgatctcca ccgagccggc ggcgggcgcc gccctgtcgc cgaactcgcc
    18541 ggtggcgctg accgtctcgc agggcatgca cccggtgccg gacgtcggcg ggatgagcaa
    18601 ggaggacgcg agcaaggcga tccaggacgc cgggttcgtg ccgcaggtcg ccgggctgat
    18661 cccgatcggc aaggtcaccg gccagtcccc gcaggcgggc accccggccc ggcagggcag
    18721 caccgtgacg atcaccgtca gcctgttcta gccggtcggc ctcagcgcag cgggccgtcc
    18781 ccgggctgct cctggtagga gtagcgctgc tcgcgccagg ggtcggccag gttgtggtag
    18841 ccgcgctcct cccagaagcc gcgccggtcg gcccgcatgt actcgacggc gcgcacccac
    18901 ttggggccct tccaggcgta caggtggggc accaccaggc ggaccgggaa gccgtgttcg
    18961 agggtgagcg ggcggccgtc gtggtgggtg gcgaagacgg tggccgggtc ggcgaagtcg
    19021 gcgagccgca ggttggcgct gtagccgtac tcggcccaga ccatcacgtg ggtgacggcc
    19081 gggtcgggcg ggacgaggtc gagcacggtc cgcgcggcga cgccggtcca ctcgttgccg
    19141 agcatcgaga acttggtgac gcagtggaag tcgccgcgga cggtggtctt gggcagcgcg
    19201 tggaaggcgg tgaagtccca actggccttc tccgcgtcgg cggtggcccc gaacacctgg
    19261 aagtcccagc tctccggctt gaaccggggc accggcccgt agtgcaggac cggccagccg
    19321 cgctgcgggc gctgccccgg ggggagcctc gggtcagtcg gcggctgcgg ttccgatcgg
    19381 tgctgaccca tgcctccatg gtgacagacg gcggacggcg aatcgcgcgc gcccccgccg
    19441 cgcacccccg gcggaaatcc gaccgccgga ggggggcacc gcaccccgaa tccgcgcgcg
    19501 cgttcgggcc agataccgcc gaacggccta atcgatccga catcaccgca ggtcagagcg
    19561 gtgcgaagcg ggcggaaata ccgcccgcga ccgcgtctgt aagcgtgaac ttactggaag
    19621 cgcacccgtt caactgccac gatgcggggc atccggacag cgaccggaat gcgcacagga
    19681 aggcaggcca tgcagggcga ccccgaggtc atcgagttcc tcaacgagca gttgaccgcc
    19741 gaactcaccg ccatcaacca gtacttcctg cacgcgaaga tgcaggagaa cttcggctgg
    19801 accaagctcg ccaagtacac ccggcacgag tccttcgacg agatgaagca cgccgaggtg
    19861 ctgaccgacc ggatcctctt cctggacggc ctgccgaact accagcggct gttccacgtc
    19921 cggatcgggc agaccgtcaa ggagatgttc gaggccgacc ggcaggtcga ggtcgaggcg
    19981 atcgaccggc tgcgccgcgg gatcgtggtg atgcgcgcca agaacgacgt cacctcggcg
    20041 aacatcttcg agtcgatcct cgccgacgag gagcaccaca tcgactacct ggacacccag
    20101 ctggagctgc tggacaagct cggcgaggcg ctctacatcg cgcagttgat cgagcagccc
    20161 gagagcagct gagccgggag cagccgagcg ggggcagccg agccgggggc tgcgtcaggc
    20221 ggccctgggg gcgccctccg gggcggctcc cgggtcggcc aggccgaggc gctcggccag
    20281 ccgggcggtg gggcaggggc gggcgccgtg ctcgccgagc agcgcctgga tgcgccgcac
    20341 gcaggaaccg cagtcggtgc cggcccggca gccctgggct atctggcgcg gggtgctggc
    20401 cccctcgtcg atcttctgct tgacctgggc ctcggtgacc gcatggcaca tgcacacgta
    20461 catgtgcggc cccttccacg ttcggtgcgg tgtactgagc cttaccttac ctggcgctcc
    20521 gggtacgaag aaggcccctc cgcaccggat cgcccggaaa cggaggggcc ttcgtcacat
    20581 ctgccgctac ggcctcactg gccgcggtac atctcggcga ccaggaacgc caggtccagc
    20641 gactggctgc ggttgagccg cgggtcgcag gccgtctcgt agcgctggtg caggtcgtcg
    20701 accagcacct cgtcgccgcc gccgacgcac tcggtgacgt cgtcgccggt cagctcgacg
    20761 tggatgccgc ccgggtgggt gccgagcgcg cggtgcacct cgaagaagcc ccggacctcg
    20821 tccagcacgt cgtcgaactt gcgggtcttg tggccgctgg aggcctcgta ggtgttgccg
    20881 tgcatcgggt cggtgatcca cacgacctgg gcgccggacg cggtgacctt ctccaccagg
    20941 gtgggcaggt ggtcgcggat cttgcccgcg cccatccggg tgatgaaggt gagccggccg
    21001 ggctcgcgct ccgggtcgag ccggtcgatc agggtcagcg cgtcgtccac cgtggtggtc
    21061 gggccgagct tgacgccgat cgggttgcgg atcctggacg cgaactc
//
