LOCUS       NZ_CP113837            25113 bp    DNA     linear   CON 26-JAN-2024
DEFINITION  Kitasatospora sp. YST-16 chromosome, complete genome.
ACCESSION   NZ_CP113837
VERSION     NZ_CP113837.1
KEYWORDS    RefSeq.
SOURCE      Kitasatospora sp. YST-16
  ORGANISM  Kitasatospora sp. YST-16
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Kitasatospora.
REFERENCE   1  (bases 1 to 7659304)
  AUTHORS   Mo,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-NOV-2022) College of Life and Environment Science,
            Hunan University of Arts and Science, No. 3150 Dongting Avenue,
            Changde, Hunan 415000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 8.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 95.0x
            Sequencing Technology             :: Oxford Nanopore PromethION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/24/2024 04:37:03
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,903
            CDSs (total)                      :: 6,801
            Genes (coding)                    :: 6,649
            CDSs (with protein)               :: 6,649
            Genes (RNA)                       :: 102
            rRNAs                             :: 9, 9, 9 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 9, 9 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 152
            CDSs (without protein)            :: 152
            Pseudo Genes (ambiguous residues) :: 0 of 152
            Pseudo Genes (frameshifted)       :: 59 of 152
            Pseudo Genes (incomplete)         :: 103 of 152
            Pseudo Genes (internal stop)      :: 5 of 152
            Pseudo Genes (multiple problems)  :: 14 of 152
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:05:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 589505
            Orig. end                         :: 614618
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP113837.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Mo Ping.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..25113
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="3"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..25113
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25113
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:15113](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15113
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    1114..1129
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.99"
                     /tool="antismash"
     gene            complement(1301..1741)
                     /locus_tag="OU787_RS02675"
                     /old_locus_tag="OU787_02675"
     CDS             complement(1301..1741)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018961491.1"
                     /locus_tag="OU787_RS02675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_02675"
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="WP_268658407.1"
                     /transl_table=11
                     /translation="MPTKKKEGEQQIEPTAEAVRAATRRRLRQPVARTNRVCPRFSDPE
                     WSLLQHAARQASLAPGGYAAAATLAAAASSDPNAAVADYRRGIQELMESNRQLGGIGNN
                     LNQVAHFLNAGGQVAADLRQLLQRVEASIAAVDDAIAWMVRR"
     gene            complement(1920..2144)
                     /locus_tag="OU787_RS02680"
                     /old_locus_tag="OU787_02680"
     CDS             complement(1920..2144)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019062435.1"
                     /locus_tag="OU787_RS02680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_02680"
                     /product="hypothetical protein"
                     /protein_id="WP_268658408.1"
                     /transl_table=11
                     /translation="MRTTPATWTEADAWLTVLHQHGHLHRAETCTDGTRTVQRSRHSRP
                     WTLHHPVLALDWIEDLVRDVEQRDTEMRR"
     gene            complement(2231..2608)
                     /locus_tag="OU787_RS02685"
                     /old_locus_tag="OU787_02685"
     CDS             complement(2231..2608)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="OU787_RS02685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="OU787_02685"
                     /product="hypothetical protein"
                     /protein_id="WP_268658409.1"
                     /transl_table=11
                     /translation="MTGSPVSLVSVLPVAVTEAADLGGQSVSGGPVSDRPAEVVPVTGS
                     PVSPVSALLVTDRAADRDTEELLKIARRAVAEADNKLTRAVVATAIRGQQIPLSSDTLT
                     QLMAQLREQQRKNQLVDADRS"
     gene            complement(2719..3426)
                     /locus_tag="OU787_RS02690"
                     /old_locus_tag="OU787_02690"
     CDS             complement(2719..3426)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1151: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046809.1"
                     /locus_tag="OU787_RS02690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_02690"
                     /product="ATP-binding protein"
                     /protein_id="WP_268658410.1"
                     /transl_table=11
                     /translation="MRHHRDPQTLADGTSVLDRMARILAARGLDRTAVDALGDEPERFS
                     PEAALSAGTPPRYRDAIADHPLVLAWARQVAAQATAPSTGARRQVATGPSLLMAGVTGA
                     GKTHQAYGAIRVLVRAGLGVRWRATTAADLYAELRPSTTTDAERVLAAYSRVPLLILDD
                     LGAAKTSEFVEEQTCRLINRRYNAMLPTLITTNLRIRDLKAYLGDRVTSRLAEMTTRVE
                     FEPVDRRRHQRAA"
     gene            complement(3426..4475)
                     /locus_tag="OU787_RS02695"
                     /old_locus_tag="OU787_02695"
     CDS             complement(3426..4475)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972990.1"
                     /locus_tag="OU787_RS02695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_02695"
                     /product="hypothetical protein"
                     /protein_id="WP_268658411.1"
                     /transl_table=11
                     /translation="MARIRSVKPETWVSETLAEVSIPAMVTFLGMTNHADDHGRHRDNA
                     AIVYGLVWPMREEVTRADVEEHLRQLAAAGAVCRYTGCDGRKYFHYPTWRNHQKIDKPS
                     LSRLPACPHCEPERCGVCKGPCIQRSALAEASTPAPEVAPTAPRVFDEPSANTPAHLVP
                     LSGPVAKPSPQGSTGSGTTTALAVGESREAIPAAGRSAGQTAFAEASPKVRRSLREPST
                     PGSRILDPGSSFPTGRQAPEPEVVSANQLVGEYVAACERRPPNGVLGHLGRTVKGLLAE
                     GIDAEHVRAGLRRFAEIQGHPSRLPSLVNDAMNARNAGLARPGLRPNLPVHQAWTNPVD
                     AATVYAEEL"
     gene            4991..5608
                     /locus_tag="OU787_RS02700"
                     /old_locus_tag="OU787_02700"
     CDS             4991..5608
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019546689.1"
                     /locus_tag="OU787_RS02700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_02700"
                     /product="hypothetical protein"
                     /protein_id="WP_268658412.1"
                     /transl_table=11
                     /translation="MTFEPPAPPTFADSTLRQKAARVVTDVLAPANLVTALLLLIGWHS
                     TRSWSGLGWGLLAAIFCGVIPISIIALGVKRGGLTDRHIRVRRQRLLPMVLSLVSVATG
                     IILLHTLGAPSDVSALVVAMLVGLVSTLLVTTGWQISLHNSVAGGTVMILALALGPWLL
                     LTMLGAAAIGWSRMVLKAHTLAQILAGTALGSVTALVFGLLR"
     gene            complement(5717..6220)
                     /locus_tag="OU787_RS02705"
                     /old_locus_tag="OU787_02705"
     CDS             complement(5717..6220)
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018087691.1"
                     /locus_tag="OU787_RS02705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_02705"
                     /product="TrmO family methyltransferase"
                     /protein_id="WP_268658413.1"
                     /transl_table=11
                     /translation="MTDREVFEVEALGHVVGGRTEPTDDFWGGTRAIIRLDGTRFTPDA
                     TKGLEDFSHLEVVFRFHLTDPTDLNLGARRPRDNPDWPEVGIFGHRNMRRLNWLGVSRC
                     RLLKVDGLDLHVEDLDAVDGTPILDVKPWFVDFGPRGEIYQAQWTTDMLGEYFAPGEDG
                     LSAE"
     misc_feature    complement(6180..6194)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     gene            complement(6265..7656)
                     /locus_tag="OU787_RS02710"
                     /old_locus_tag="OU787_02710"
     CDS             complement(6265..7656)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015662459.1"
                     /locus_tag="OU787_RS02710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_02710"
                     /product="Tat pathway signal protein"
                     /protein_id="WP_268658414.1"
                     /transl_table=11
                     /translation="MAKEVRVNERLQQAIRESRMTYDRLALELGIVAGSHGDDARPGKS
                     LISHWVRYSVVPSGDMPSYLAAVLSRRLGRTVTPADLGLAEEVSDLRDWSLDTLSVLAD
                     LRRIDVDDVEVDRSTALQLMAYSVGALALPTESWWESMARTGEARGRAGGRRVGEADVE
                     AVRDMTGLFSQVDQRRGGGHARTAVVQYLTSDVARFLKGTFASEGTRRQMFSAAAELAY
                     VAGWMAFDSADHAAAQTYFGQAVRLAAEADDPAMAGHVLRAMAHQALDLGHPKQALDLA
                     AASISGDRYALACPRERALLGVIHARGLAATGRHTAATGALLQAQRDLAAAAPGDDEPA
                     RVFFFGEASLAHETASALRDIGDLAGAVKEFRHSVETRKASSFARTHAVTLGYLGAVHV
                     RLKNIEEACAVWSDALDAMEPVRSGRTRQTATHMRTALSPFRQRGIRSIDRVDSRAAAY
                     LEATA"
     gene            7832..8266
                     /locus_tag="OU787_RS02715"
                     /old_locus_tag="OU787_02715"
     CDS             7832..8266
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024970.4"
                     /locus_tag="OU787_RS02715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_02715"
                     /product="ATP-binding protein"
                     /protein_id="WP_268658415.1"
                     /transl_table=11
                     /translation="MDVTVQGLRLWEQEFPATPASARLARGAVRRSLLGWGWAPERIDD
                     MVLICSELVTNAIRHACRAGEVVPVRLQEIDGDCWLEVRDNRSELRPRPRPAGVRVDGQ
                     GLLLVADLSDDWGVTVDLGAKTVWARLSGQSQHSDVGEAA"
     misc_feature    8361..8374
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.07"
                     /tool="antismash"
     misc_feature    complement(8439..8453)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.85"
                     /tool="antismash"
     gene            8447..9679
                     /gene="fxlM"
                     /locus_tag="OU787_RS02720"
                     /old_locus_tag="OU787_02720"
     CDS             8447..9679
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006346494.1"
                     /locus_tag="OU787_RS02720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_02720"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_268658416.1"
                     /sec_met_domain="PCMT (E-value: 3.9e-34, bitscore: 116.9,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTLADSVGRSLPDGDEALRTAMVEALRSSGALRTDRVAAALLAV
                     PRHVFAPEVPVAEAYEPERALVTKRDEYGLAVSSVSAARIQAQMLEQADVRPGMRVLEV
                     GSGGYNAALIAEVVGPDGEVVTVDIDPFVTDRAQKYLAEAGYERVRVVLADGSGPVEGG
                     PFDRIIVTVGAWDLPPAWTGALVEGGTITVPLRMHGLTRSITFRREGERLVSVSATVSG
                     FVKIQGADAHDEFLVLPRGTKEIGLRFDELERPDTSRLGGVLDTPRAEWWSGVTVGNQE
                     PFDSLYLWLASSLPGFGLMSVDPELDTKTVAPANRMACPVIVDGDSLAYLALRRIADDP
                     VTFEFGAHGFGPDEGPLAALINTEVRKWDREHRTSDGPVFTAQPIGTPNDQLPDGLVVD
                     KTHVRLTISWP"
     gene            9723..9887
                     /locus_tag="OU787_RS02725"
                     /old_locus_tag="OU787_02725"
     CDS             9723..9887
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014054575.1"
                     /locus_tag="OU787_RS02725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_02725"
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_268658417.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 3.4e-16, bitscore:
                     57.5, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTTITGTAAASDFELDVTIVEGADPVAALLRSTDDGCGSTCSGT
                     ACTSFGGNV"
     CDS_motif       9723..9803
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSTTITGTAAASDFELDVTIVEGADPV"
                     /locus_tag="OU787_RS02725_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9804..9887
                     /prepeptide="core"
                     /locus_tag="OU787_RS02725_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="-0.80"
                     /molecular_weight="2407.6"
                     /monoisotopic_mass="2406.1"
                     /core_sequence="AALLRSTDDGCGSTCSGTACTSFGGNV"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSTTITGTAAASDFELDVTIVEGADPV"
                     /leader_location="[9722:9803](+)"
                     /alternative_weights="2425.6"
                     /alternative_weights="2443.6"
                     /alternative_weights="2461.6"
                     /alternative_weights="2479.7"
                     /alternative_weights="2497.7"
     gene            10001..13084
                     /locus_tag="OU787_RS02730"
                     /old_locus_tag="OU787_02730"
     CDS             10001..13084
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.4"
                     /locus_tag="OU787_RS02730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_02730"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_268658418.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.5e-161,
                     bitscore: 537.4, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 5.1e-13,
                     bitscore: 48.2, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.2e-31, bitscore:
                     109.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYAVAGPALLRAAARPAAAGPSWWPDLADTGPHATANWRAWLQHV
                     WSDADFAAAVEVGAGPQLAARVREVVFNFDHVPRRRLRRLTASVMQYALRQQRPTPFGL
                     FAGVTAVPFGEVAAAPRWGASRVVARPDARWLASVVRELEEAVGDLLPVTANQLRVRRG
                     ERVVLPVTRNPQDSEPAEVSVRATGPVLAVLEAADGPVSVTLGELADRFPAAPADKVRA
                     MLSELVRQGFLISILRLPTTVTDPLGHLLAIAHTTGLDQIPAAEATWNTLRTVREQLAR
                     HNELDDPTKQQTLRTRLTRQLTRQPGWVPGGSTPLMVDLRLDAGPAVLPERVASLVAGA
                     AEVLTRLSPFPDGHPVWVDYHRRFAERFGPGAVVPVLELVNPDTGMGFPARYRDSVLPD
                     VPPQFGRRDAQLLALAQMATVERLDQVDLNGPLLERLAPDPVPDGAVQPHAELTVRLSA
                     YGVGPFTYGAAQFAPVVQAVPRGAGTTAGRFLYLLEPERRRELEAAITAAPPLRADALV
                     VQVSAPPLYARAENVSRAPALLPLLALGEYPQIGEGLLRLEELGVCADERRMWLVRFSD
                     RRPVEVRVLNAVDFRANTDPLVRFLCEITHAHTPWLTAFNWGAAGQLPYLPRVRYGEVV
                     LSPARWHLPAADLPGKDADWEEWRAAAGEWIARYNVPATVYLSQQDLRLPLDLRVPEHL
                     VLLRDHLLREPTAILIEAPRAVDNQWCGRAHEVTVQLHSTRTPLPAARPRPGRPVTVRS
                     GHLPGASGWLSARLFGNPRRADELLARVPGLAAGWVVPPQWWFLRHTDPEPHVRLRIPV
                     SAVAAWSLASERIGRWAEQMREEGLLTRMELDTYLPESGRYGRGAALRAAEEFFSLDSR
                     TVLAQLAYQRATSTDPATMTAASMLDLATALLGREAGHAWLLERVPRHSKIALPRSASR
                     LAAELADRPDQLELTAEGRLLSLEWRVRAKKLADYRRALCRDGELEPADVLGSLLHLHH
                     ARAVGLNPASERTCHRLARAAALTLTARTARAEEGQPA"
     aSDomain        10457..10714
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_OU787_RS02730_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="2.10E-15"
                     /identifier="RREFam001.1"
                     /label="OU787_RS02730"
                     /locus_tag="OU787_RS02730"
                     /protein_end="238"
                     /protein_start="152"
                     /score="48.2"
                     /tool="antismash"
                     /translation="VTANQLRVRRGERVVLPVTRNPQDSEPAEVSVRATGPVLAVLEAA
                     DGPVSVTLGELADRFPAAPADKVRAMLSELVRQGFLISILR"
     gene            13081..14241
                     /locus_tag="OU787_RS02735"
                     /old_locus_tag="OU787_02735"
     CDS             13081..14241
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /locus_tag="OU787_RS02735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_02735"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_268658419.1"
                     /sec_met_domain="LANC_like (E-value: 6.5e-40, bitscore:
                     135.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAELLAPPAEVSAQWGQSLAKGGLATALLHIERAATGRGSWDTA
                     HEWITACLSQPVNSFTGASVFYGAPAVAHVLHLAALHGPRAYHQPRMLLDTAVEHVVEQ
                     RLAAAHRRIDAGQRPEFHEFDLLGGLTGLGAHLRVRGRQELLREVLSYLVWLTAPVHGR
                     SGWWTHLAPSGDPDDRYPGGHGNFGIAHGIPGPLTLLALTYLDGTRVPGQLEAIERILD
                     WLDAWQQNGAARAWWPEALTAAEADEGRTRQSKPLRPSWCYGTPGIATALHHAARTIGD
                     PDRARTAEAAFLDAIEDPDQAHSLTDGTVCHGTAGVRLAAQRFAERTDDHATALRILAA
                     ASNLPDPGSDATGHGLLEGTAGIALTRCSLAAECPGAGWDALLLLI"
     gene            14259..15113
                     /locus_tag="OU787_RS02740"
                     /old_locus_tag="OU787_02740"
     CDS             14259..15113
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03891.1"
                     /locus_tag="OU787_RS02740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_02740"
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_268658420.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.5e-30, bitscore:
                     105.4, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPATGDHTWTQVHLHLATDTPEEHAVRLLGPALIALEDQGLIGCW
                     HFLRKGDRWRLRYREAASGTLEATATAAAVNEVLDMCREAGMISDWTPAIYEPETYVFG
                     GAAALPAAHRLFHQDSRHALTYLTAVHRGELSDQRAELWLLLGTAAMRGAGLDWYEIGD
                     TWAQVAENRSADGPGLAVPDRRLVDAARTLLQADTTPGSALLEGRLAHAASWFGAFAAY
                     GLTLRTLADEGQLWRGQRAVLAHHQLFTANRLGLPYHQQAALASAAAGAVLDLVEANEA
                     VLR"
     gene            15110..16264
                     /locus_tag="OU787_RS02745"
                     /old_locus_tag="OU787_02745"
     CDS             15110..16264
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="OU787_RS02745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="OU787_02745"
                     /product="hypothetical protein"
                     /protein_id="WP_268658421.1"
                     /transl_table=11
                     /translation="MSAQRTAQPTGPLGDALARLPLVPRRHALAAPLEQRVHQLTDLAR
                     QATDTENPATAASVHNRAALLASDRGLPGLARVLCLNHAGFYLARRPLTVYLARLVFEP
                     LVNLAHLELRAGNGIPALAILDELLRAVADNDDATLPGGLIIPLAGLTASSTDRADVHK
                     WLTDIQVFEGTRALARAGRWTEAHFHLRQSTDRSDRLFEGRQVAVVAMAFEGRTALARA
                     LARDTPAEQPWEHAIAAALTVACTLLDGDPAADQAEVMLRAHAAVTPRQGSEVFDTRLA
                     LTVADLATAAGRLPDAARVYLTAVGRTLADPEGYSARDLARHRLADGLPAEQRHRLAAI
                     AAECGVGGPATLTTDHDDRITAALTLAAAVITKAAAKSLSPSRP"
     gene            16363..17322
                     /locus_tag="OU787_RS02750"
                     /old_locus_tag="OU787_02750"
     CDS             16363..17322
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="OU787_RS02750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="OU787_02750"
                     /product="hypothetical protein"
                     /protein_id="WP_268658422.1"
                     /transl_table=11
                     /translation="MSNTLTTARPEPGALGSFVHVGWNIQHGWKLTQAIDHLRQFAQER
                     GAERPHLLTLQELQEDQAAEVAQQLQLDFVEAPNERPGSRNALFFAPELFQADPEWIPY
                     TNAVRHRPATAKLRCIHPHTGALSKREVSVASVHLNFGDPGDREHQIRWLLANMYKDRW
                     LAFFQGDMNSWPVWGCPLRLDGAEDKAWVVDRSIVLPDGTTRPDDVPDRLMTLRGMVNI
                     GRYAATVLGQAGADGPTTWDGPKKARQRIPGEDLPPGSLGGIDHGYTAEELMRALISAT
                     IPNTPQVQEVSDHLPQVTEWDTEVWWEVMDAEVELVRH"
     gene            complement(17360..18076)
                     /locus_tag="OU787_RS02755"
                     /old_locus_tag="OU787_02755"
     CDS             complement(17360..18076)
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031441.1"
                     /locus_tag="OU787_RS02755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_02755"
                     /product="flavodoxin family protein"
                     /protein_id="WP_268658423.1"
                     /transl_table=11
                     /translation="MPAPGTSYGDLRALVINCTLKRSPERSHTQGLIDISTGIMERQGV
                     AVEVLRAVDIDIATGVWPDMTEHGWESDEWPVIYSKVMAADILTLAGPVWLGDNSSVMK
                     RVIERLYSCSSVLNQHGQYAYYGRVGGCLITGNEDGAKHCAMNVLYSLQHLGYTIPPQA
                     DAGWVGPAGPGPSYLDEGSGGPENDFTNRNTTFMTWNQLHLARMLKDAGGLPVHGNQRS
                     EWDAGCRFDFENPEHR"
     gene            complement(18186..18803)
                     /locus_tag="OU787_RS02760"
                     /old_locus_tag="OU787_02760"
     CDS             complement(18186..18803)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039495.3"
                     /locus_tag="OU787_RS02760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_02760"
                     /product="hypothetical protein"
                     /protein_id="WP_268658424.1"
                     /transl_table=11
                     /translation="MATYRCVKSGLPVAAEQISVMAEGGWCFITGSRESAVAVASALGG
                     RLDEADPRGSSPASMVRTGAHSLSITMHGAESISFRMVHRGVRGSGKVRADHRNCHRPA
                     ALEVKQCGRGTGLAEQRSAARSGHGAKPEIKIAFRLTEAPSLGVFEFATSSWTLAGMLE
                     PVLRAFSGGRASLRCELRIESRGFETSDGVQVTYHEPVLVLG"
     gene            complement(18947..20506)
                     /locus_tag="OU787_RS02765"
                     /old_locus_tag="OU787_02765"
     CDS             complement(18947..20506)
                     /GO_function="GO:0000150 - DNA strand exchange activity
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012464.4"
                     /locus_tag="OU787_RS02765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_02765"
                     /product="recombinase family protein"
                     /protein_id="WP_268658425.1"
                     /transl_table=11
                     /translation="MTDLPYVDLYLRKSRVVRDEDPRDLTSIQSQENTGRAWAAREGCR
                     VREVWVDNLSAWSDIERPEFDKALAAVLAGEVPALWCAFLDRFTRKGIDDIGPILGKAR
                     VIFDYEGLDSSIERDRRWIIDRAEQAREYSNRLSYNIKSTKATMRARGQWTQMAPYGLC
                     ADKARKLRHAPETWRIVLHVVKCVALGFSQRSVAKALNSGPNPVPGPGGGRWQANAISR
                     ILHNPVYEGWQVAPRRQKATRGRFEAFRDRDGNRVSVLAEGVEPVPADLLARARQVAAG
                     FTFASPDQAARVGTTRELLTDAVKCPGCRSGASPDSQNYRCWRAVQGDVCPAPVSVSRA
                     RLEEYVTEAWFSWMNAAEPDDLLLVKAAQRWKGLQQPDNGAELAEATAALKSAEAGIKR
                     LVEQQASGFFDPPFDTHLPVLQAEARTALENAKRRVADASPKRLDVSFLLEDAAIRQAW
                     AEADLPLRRELLRLVIRRVVVTKGRRGCNVFDGPSRVEIHWLDQPDPWLKPKDQGSFAA
                     AA"
     gene            complement(<20578..20847)
                     /locus_tag="OU787_RS02770"
                     /old_locus_tag="OU787_02770"
                     /pseudo=""
     CDS             complement(<20578..20847)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018559468.1"
                     /locus_tag="OU787_RS02770"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_02770"
                     /product="flavodoxin family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTQYTDLRAVFLNCTLKRSPERSHTQGLIDISAGILRRQGVQVEE
                     IRAVDHDIATGVWPDMTEHGWDTDEWPVLYSQLMNADILTLAGPV"
     gene            21007..21501
                     /locus_tag="OU787_RS02775"
                     /old_locus_tag="OU787_02775"
     CDS             21007..21501
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014134243.1"
                     /locus_tag="OU787_RS02775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_02775"
                     /product="glutathione peroxidase"
                     /protein_id="WP_030461702.1"
                     /transl_table=11
                     /translation="MVDSLFELPIRTLAGEPSSLGEYRSQVLLLVNVASKCGLTPQYAG
                     LERLQEKYGERGFTVLGFPCNQFMGQEPGSAEEIQEFCSTTYGVSFPLFEKIDVNGAER
                     HPLYARLTEVADATGEAGDVQWNFEKFLVSADGEVVGRFRPRTEPESAELVAAIEAQLA
                     G"
     misc_feature    21538..21556
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.3"
                     /tool="antismash"
     gene            21621..22205
                     /locus_tag="OU787_RS02780"
                     /old_locus_tag="OU787_02780"
     CDS             21621..22205
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027: isochorismatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014134244.1"
                     /locus_tag="OU787_RS02780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_02780"
                     /product="isochorismatase family protein"
                     /protein_id="WP_268658426.1"
                     /transl_table=11
                     /translation="MSVTALDPNTALVVIDLQQGILAIPGAPYPTTEVLARNVALAAAF
                     RAAKLPVVLVRVSFATDGGDVPPGRTEQNRAGGAAPRPEGWDRLAAELHDPSDLVVTKH
                     NWGAFHGTDLDVQLRRRGVTQIVLTGVATSIGVESTARAAFEHGYHVTPVVDAMTDMDA
                     EAHRHSVERIFPRLGETGTTEEVLALLAAER"
     gene            complement(22335..22568)
                     /locus_tag="OU787_RS02785"
                     /old_locus_tag="OU787_02785"
     CDS             complement(22335..22568)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056860.1"
                     /locus_tag="OU787_RS02785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_02785"
                     /product="hypothetical protein"
                     /protein_id="WP_030461700.1"
                     /transl_table=11
                     /translation="MTSNSTAEEPLVRVAEFRTDSRYRLVHFQGEGWKPLAPEEFEPEL
                     HHHFPDLDPHDPARVHWDDRPWEWPAWRPGEA"
     gene            22762..23139
                     /locus_tag="OU787_RS02790"
                     /old_locus_tag="OU787_02790"
     CDS             22762..23139
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018508.4"
                     /locus_tag="OU787_RS02790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="OU787_02790"
                     /product="YkvA family protein"
                     /protein_id="WP_081967069.1"
                     /transl_table=11
                     /translation="MGRGKGRAARVRGLDGAAVARSAWGLYRETRRPGAPGLGARALAL
                     PRLLRDVLAGRYPGVGPGKLAALTVAVGVYLLSPVDAVPDFLPLIGWGDDTALLLWFLM
                     GLTRESGRYLEWAGDRSPRND"
     misc_feature    complement(22775..22789)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 27.18"
                     /tool="antismash"
     misc_feature    23148..23164
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 17.18"
                     /tool="antismash"
     misc_feature    23744..23762
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 22.93"
                     /tool="antismash"
     misc_feature    complement(23745..23763)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 22.16"
                     /tool="antismash"
     misc_feature    24494..24510
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 19.89"
                     /tool="antismash"
     misc_feature    complement(24569..24582)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.57"
                     /tool="antismash"
ORIGIN
        1 ggcgctctgc cggtaggcgg cgcgcaggtg ttcggcggcc tggcgggagg ctgcggcctg
       61 ctgggcgtgg ccgcgggcgg agtgccagcg ggcggcggcc agggtgagca ggacgagggt
      121 ggacaggacc atcgcggtgg cgccgccgtc ctctcctcgt ccaagcgccg ttccggcgtg
      181 gactattgcg cgggcggccg aacgcagggc ccggatgtcc gccttctcgg cgcggacgtg
      241 ggagcgggtg gcgcgctcga acgcgcgcgc ggcgtcacgt agttcggtgc gggtggcggc
      301 cggggaggtc tgggcgagcg cgccgacgag ctgggcggcg gcttcgtcgc cgccctcgtc
      361 gagaagggcg gtggcgcgct cggcggtgtc ggcggcggca cgccgggtgc gggcgggggc
      421 ggaccggtcg gtacgggacg tgccggtgcg gggcgggacg gtgtcggcgg gtgcgtcggt
      481 caggcggcgg cggatgcgcg gcagggagag gtcggggcga gggtggaccc ggcgaaccag
      541 acgggctcct tgctcgcgtt gcggtcgccg ggcagggcga cgttgtagcc gagcacgtcg
      601 ccggaggggg cgtggcggag cttcacccgc aggccggcct cgcgcagccg gtcgaagaac
      661 tcggcctcgg tggccgctcc ggcgacggcc tggcggacgg cttcgcgcag ggtttcgcgc
      721 ggggtctcgg cgcgaccggt gcgctcggcc ttccagcgct cttggctggt gggtttcttg
      781 gcggcagtgc cgtcgccggg ggcgagttgg cgcaggccgt agtcctgttc gatgcggcgg
      841 gcttcggcct gggccttgcg gcggtcgaag gaaaggccag cgaggcggcc gtcctggcgc
      901 accagggtgg cggcgatgtg gatgtggtcg tcggcgtggc ggacggcgac ccagcggcag
      961 gcggtggtgt cgccgtcggg ggcgatgccg gtagcgtgga cgatacggcg ggcgatgttc
     1021 gcccagtcgg cgtcgtcgag gtggcggtcg ccggggtcgg cgcgcaccga gcagtgccag
     1081 atggtggtgg cgggggcgcg gtcgccgatg gccttgacgg gttggtcgag ctggttggcg
     1141 agttgggcga cggtgtggtg ggggttgcgg ccggggtcgg gggcgaagcc gttccaactg
     1201 gccacgacgt gctggtcggt gtgctcgtcc tgcctgccgg gtccgaagag gtagcggatc
     1261 aggccgtagg tgccgccggt gccggtgcgg atcttgggga tcaccggcgg accatccagg
     1321 cgatggcgtc gtcgaccgcg gcgatggagg cttcaacgcg ctgcaggagc tggcggaggt
     1381 cggcggccac ctggcctccg gcgttgagga agtgggcgac ctggttcaag ttgttgccga
     1441 tgcctccgag ttggcggttg gactccatga gttcctggat gccgcgccgg tagtcggcga
     1501 cagcggcgtt cggatcactg ctcgcggcgg cggccagggt cgcggcggcg gcgtagccgc
     1561 ccggggcgag gctggcctgc cgggcggcat gctggaggag ggaccactcg gggtcactga
     1621 agcgggggca gacgcggttg gtgcgcgcga cgggctggcg cagtcggcgg cgggtggcgg
     1681 cgcggacggc ttcagcggtc ggctcgatct gctgctcccc ctccttcttc ttcgtcggca
     1741 cccccgggcc gactccccgt ccggtggcag gccccctggg tctgccaccg gacggggtgc
     1801 tcccgccccc gtgggggtgg gggcggggta aggactcctt accccacaac ttgctccgcc
     1861 aggagcctgg ttgggatcgc ttaccgctcg cggtggtgtg gccttcgggt cggtgccggt
     1921 catcggcgca tctccgtgtc gcgctgctcg acgtcgcgga cgaggtcctc gatccagtcg
     1981 agggccagga ccgggtggtg gagggtccag ggccgggagt gccggcttcg ttggacggtg
     2041 cgggtgccgt cggtgcaggt ttcggcgcgg tggaggtggc catgctggtg caggacggtc
     2101 agccaggcgt ccgcttcggt ccaggtggcg ggggtggtgc gcatgacggt gctccacttc
     2161 ggtgatgcgg tggcgggtgg gtgaccggcc ggggtgacct tctgagtcgg ccccggccgg
     2221 tcggtgtcga tcagctccgg tcggcgtcga cgagctggtt cttgcgctgc tgttcgcgga
     2281 gctgggccat cagctgggtc agggtgtcgc tggacagcgg gatctgctga ccgcggatcg
     2341 cggtcgcgac cacggcgcgg gtcagcttgt tgtccgcctc cgcgaccgcc cgcctggcga
     2401 tcttcagcag ttcctcggtg tcccggtcag ccgcccggtc agtgacgagc agcgcgctga
     2461 ccgggctgac cggcgagccg gtcaccggga cgacctcggc cggacggtca ctgaccggtc
     2521 cgccgctgac cgactgaccg cccaggtcag cggcctcggt caccgccaca ggcagcacgc
     2581 tgaccaggct gaccggcgag ccggtcaccc gaaccgacct cggctgggcg gccagtgacc
     2641 gcgcaggcgg tctgctgacc ggattcgaga gcactggtga ccaccggaat gggacagcgc
     2701 ggcgggggcg gcggctgttc aggcggcgcg ctggtggcgt ctgcggtcga ccggttcgaa
     2761 ctcgacccgg gtggtcatct cggcgaggcg ggaggtgacg cggtcgccga ggtacgcctt
     2821 gaggtccctg atccgcaggt tcgtcgtgat cagggtcggg agcatcgcgt tgtaccggcg
     2881 gttgatcagc cggcaggtct gctcctcgac gaactcgctg gtcttggcgg cgccgaggtc
     2941 gtcgaggatc agcagcggca cccggctgta ggcggcgagc acccgctcgg cgtcggtggt
     3001 ggtgctgggg cggagttcgg cgtagaggtc ggcggcggtg gtcgcgcgcc agcgcacgcc
     3061 gaggccggct cgcaccagga cgcggatcgc gccgtacgcc tggtgggtct tgcccgcgcc
     3121 ggtcaccccg gccatcagca ggctggggcc ggtggcgacc tggcggcgcg cgccggtgct
     3181 cggggcggtg gcctgggcgg cgacctgccg ggcccaggcc agcaccagcg ggtggtcggc
     3241 gatggcgtcg cggtagcggg gcggcgtccc ggcggacagc gcggcctccg gcgagaaccg
     3301 ctccggctcg tcgccgaggg cgtccaccgc ggtacggtcg aggccccggg cggcgaggat
     3361 ccgggccatc cggtccagga cggaggtccc gtcggcgagg gtctgcgggt cgcggtggtg
     3421 gcgcatcaca gctcctcggc atagacggtg gcggcgtcga ccgggttggt ccacgcctgg
     3481 tgaacaggca ggttagggcg caatcccggc cgggccaaac cagcgttccg ggcgttcatg
     3541 gcgtcgttga ccaggctcgg cagccgcgac gggtggccct ggatctcggc gaagcgccgc
     3601 agcccggccc ggacgtgctc agcgtcgatg ccctcggcca gcaggccctt gacggtcctg
     3661 ccgaggtggc cgagcacgcc gttcggcggg cgccgctcgc aggcggcgac gtactcgccg
     3721 acgagctggt tggccgagac gacctccggc tcgggcgctt ggcgccccgt agggaaagaa
     3781 gatccaggat ccaagatcct agatccaggc gtcgagggct cccggaggct tcgccgaacc
     3841 ttcggagagg cttcggcaaa tgccgtctga cctgcacttc ttccagcggc gggaatggcc
     3901 tcgcggctct ccccgaccgc cagggccgtg gtcgtgccgc tgccggtgct gccctgcggg
     3961 gacggcttcg cgacaggtcc ggagaggggg acgaggtggg cgggagtgtt cgccgagggc
     4021 tcgtcgaaca ctcggggagc ggtcggggcg acctcgggcg cgggggtcga cgcctcggcg
     4081 agggcgctgc gctggatgca cggacccttg cagacgccgc accgctccgg ctcgcagtgc
     4141 gggcaggcgg gcagccggga cagcgacggc ttgtcgatct tctggtggtt gcgccaggtc
     4201 gggtagtgga agtacttccg gccgtcgcag ccggtgtagc ggcacacggc cccggcggcg
     4261 gcgagctgcc ggaggtgctc ctcgacgtcg gcgcgggtga cctcctcgcg catcggccac
     4321 accaggccgt agacgatcgc ggcgttgtcg cggtgacggc cgtggtcgtc ggcgtggttg
     4381 gtcatgccga ggaaggtgac catcgcgggg atggagacct cagcgagcgt ctcgctcacc
     4441 caggtctcgg gcttgaccga tcggatgcgc gccatgtcag cggccccgaa cggcggtccg
     4501 tgcaccgtgc accttgccaa ctggctgcac accagggcga aggcgccggc tgcgacaggg
     4561 cggtgccggg ttttccgttt ccgtcatggg tacgcgcaag ccatactccg tgcttcgtag
     4621 gagcgcgtgc ggcggtctct cgggcatgga agtccgccga gcgcgcggtg gggaatcggc
     4681 cacttcggag ggccggtgcg gcgtccagga gttggtgctt ctggacgccg gtatcgtctt
     4741 cggtcggcgt gggcagcggc ccatcagcct gcctgccgtg tgcggcagga ccagaaccat
     4801 aggccgcacc gcgggcactc atccaccctg ttaagccacc cgaccagtca cgacgaacct
     4861 tggctttccc cttcgcacgg tcttccgctc actgttgaga agctgtgcgc gaacgccgcg
     4921 ccgatgcgcg gccggagacc acacgcgtac gccgtcgcgt acgacccgac cgcccttccg
     4981 gagccacccc gtgacgttcg aaccacccgc tccgcccacc ttcgccgaca gcacacttcg
     5041 ccagaaggcc gcgcgggtcg tcacggacgt cctcgccccg gccaacctgg tgaccgcgct
     5101 cctgttgctg atcggctggc acagcacccg ctcctggtcg ggcctcggct gggggctgct
     5161 ggccgcgatc ttctgcggcg tcatcccgat aagcatcatc gcgctcggtg tgaaacgcgg
     5221 cggtctcacc gacaggcaca tccgcgtccg ccgtcagcga ctcctgccga tggtgctcag
     5281 cctggtgtcg gtcgccaccg gcatcatcct gctgcacacc ctcggcgccc cgtctgacgt
     5341 gtccgcgctg gtcgtcgcga tgctcgtggg gctggtctcc accctcctcg tcaccaccgg
     5401 gtggcagatc tccctccaca acagcgtcgc tggcggcacc gtcatgatcc tcgcgctcgc
     5461 cctcggtccc tggctgctgc tcaccatgct cggtgccgcg gcgatcggct ggtcccgcat
     5521 ggtcctcaag gcccacaccc tcgcgcagat cctggccggc accgccctcg gcagcgtcac
     5581 ggccctggtc ttcggcctcc tgcgctgaac cgtcggggcg ccctcacccg gggcgtccga
     5641 agtggggccg cccagcaggc cacttcggac gccccctttc ggattcggct tccgcggagg
     5701 gaagttaacc gctcggctac tcggcgctca ggccgtcctc gcccggggcg aagtactcac
     5761 ccagcatgtc ggtggtccac tgcgcctggt agatctcacc gcgggggccg aagtcgacga
     5821 accagggctt cacgtcgagg atcggggtgc cgtcgacggc gtcgaggtcc tccacgtgga
     5881 ggtcaaggcc atccaccttg aggagtcggc agcgcgagac gccgagccag ttcaggcggc
     5941 gcatgttgcg gtggccgaag atgccgacct cgggccagtc ggggttgtcg cgcgggcggc
     6001 gggcgccgag gttgaggtcg gtggggtcag tgaggtggaa gcggaagacg acctccaggt
     6061 gggagaagtc ctccaatccc ttggtggcgt cgggggtgaa gcgggtgccg tcgagtcgga
     6121 tgatcgcccg ggtgccgccc cagaagtcgt cggtgggttc ggtgcggccg cccaccacgt
     6181 ggccgagggc ctcgacttcg aacacctcgc ggtcggtcat gatcggttct cctcctgcgg
     6241 tcggggtggt gacggtacgt cggttcacgc ggtggcttcc aggtaggcgg ccgcccggct
     6301 gtcgacccgg tcgatgctgc ggatgccgcg ctgccggaac ggcgagaggg cggtgcgcat
     6361 gtgcgtggcg gtctgccggg tgcgcccgga ccggacgggc tccatcgcgt ccagtgcgtc
     6421 cgaccagacg gcgcaggctt cctcgatgtt cttgagccgg acgtggacgg cgcccaggta
     6481 gccgagggtg acggcgtgcg tccgggcgaa ggagctggcc ttgcgggtct cgacgctgtg
     6541 ccggaactcc ttcaccgcac cggcgagatc gcctatgtcg cgcagggcgg aggcggtctc
     6601 gtgcgccagg ctcgcctcgc cgaagaagaa cacccgggcc ggttcgtcgt cgcccggtgc
     6661 cgctgcggcg agatcgcgct gggcttggag cagggcaccg gtggcggccg tgtgccggcc
     6721 ggtcgccgcc aggccccggg cgtggatcac cccgagcagc gcgcgttcgc gcgggcaggc
     6781 gagcgcgtac cggtctccgc tgatggacgc cgcggcgagg tcgagcgcct gcttcgggtg
     6841 cccgaggtcg agtgcctggt gggccatcgc ccgcaggacg tggccggcca tcgccgggtc
     6901 gtccgcctcg gccgccagcc ggaccgcctg cccgaagtag gtctgggctg cggcgtggtc
     6961 ggcgctgtcg aaggccatcc agcctgccac gtaagcgagt tcggccgcag cggagaacat
     7021 ctgccgacgc gtcccctccg aggcgaaggt gcccttcagg aatcgtgcga cgtcgctcgt
     7081 gaggtactgc accacggcgg tgcgggcgtg gccgccgccg cgtcgctggt cgacctggga
     7141 gaacagaccg gtcatgtcgc ggaccgcctc gacgtccgct tcaccgaccc gtcggccacc
     7201 ggctcgtccg cgcgcctcgc ccgtgcgcgc catcgactcc caccagctct cggtgggaag
     7261 tgcgagcgcg ccgacggagt aggccatcag ctggagggcg gtgctgcgat ccacttccac
     7321 gtcgtccacg tcgattcgtc ggagatcggc caagacgctc agcgtatcca agctccagtc
     7381 ccgaagatcg ctcacctctt cggccaggcc gaggtcggcc ggggtgacgg tccgcccgag
     7441 ccgacgggac agcacggcgg cgaggtagga cggcatgtcc cccgacggca ccacgctgta
     7501 gcgcacccag tgactgatca acgacttgcc cgggcgggcg tcgtcaccgt ggctacctgc
     7561 gacgatgccc agctccaggg ccaggcggtc gtacgtcatc cgggattccc tgatggcctg
     7621 ctgcaggcgc tcgttgaccc gaacttcctt cgccatcacg tcccctgact tcccgttaaa
     7681 cgggttaaac cgccgggagt ggccaacacc ttactcccgg tcgccaacca cggttgtctt
     7741 gagcaagcgg gcggcaccgt ccgaacacca actgccggga acagccgtgc ggttcgtggg
     7801 gcagcgaccg gagacggcgg agggagcggg cgtggacgtg acagtacagg gactccgact
     7861 gtgggagcag gagtttccgg cgacaccggc atcggcccga ctggcccgtg gcgctgtccg
     7921 gcggagcctc ctggggtggg gatgggctcc ggagcgcatc gacgacatgg tcctgatctg
     7981 ctcggagttg gtcaccaacg ccatccgcca cgcctgccgt gccggcgagg tcgtacccgt
     8041 gcggctccag gagatcgacg gtgactgctg gttggaggtc cgcgacaacc ggtccgaact
     8101 ccgaccgcgc ccgcgccccg caggtgtgcg cgtggacggg caagggcttc tgctggtcgc
     8161 cgatctgtcc gatgactggg gggtgacggt tgatcttgga gcgaagaccg tgtgggcccg
     8221 gctgtcgggg cagtcgcaac actcggacgt cggggaggcc gcttgagtgg gggcaagcct
     8281 cggatatcgg cgccaggtct cgcatctctc ggtgacggca gctcggcgac gcggtgatct
     8341 gctccgggca cgcgctgatg actttcccag aaaagggagt tgggacgttg ccacgtcccg
     8401 gctccgggac ggtgccgcat ccgtgcggcg aatcaagagg agaacgatgt ccaccttggc
     8461 agactcggtc ggccggtcgt tgccggacgg ggatgaggcg ctgcgcaccg cgatggtgga
     8521 ggcactgcgc tccagcggcg cgctccgtac ggaccgggtg gcggccgcgc tgctggccgt
     8581 gccccggcac gtgttcgcgc ccgaggtgcc ggtcgcggag gcgtacgagc ccgagcgggc
     8641 gctggtgacc aagcgggacg agtacgggct cgcggtcagt tcggtgtcgg ccgcgcggat
     8701 ccaggcgcag atgctggagc aggcggacgt acggccgggg atgcgggtgc tggaggtcgg
     8761 ctccgggggc tacaacgcgg cgctgatcgc cgaagtcgtc ggcccggacg gcgaggtggt
     8821 gacggtcgac atcgacccgt tcgtcaccga ccgcgcgcag aagtacctcg cggaggccgg
     8881 gtacgagcgg gtgcgggtgg tgctggcgga cggctccggg ccggtggagg gcggcccgtt
     8941 cgaccggatc atcgtcacgg tcggggcgtg ggacctgccg ccggcgtgga ccggcgctct
     9001 ggtcgaaggc ggcacgatca ccgtgccgct gcggatgcac gggctgaccc gctcgatcac
     9061 cttccgccgg gagggcgagc ggctggtgag cgtgtccgcc acggtctccg ggttcgtcaa
     9121 gatccagggc gcggacgcgc acgacgagtt cctggtgctg ccgcgcggca ccaaggagat
     9181 cgggctgcgc ttcgatgagc tggagcgccc ggacaccagc cgtctgggcg gcgtgctgga
     9241 cacgccccgc gcggagtggt ggagcggggt tacggtcggc aaccaggagc ccttcgactc
     9301 gctgtacctg tggctggcgt cctcgctgcc cgggttcggc ctgatgtccg tggacccgga
     9361 gctggacacc aagacggtcg ccccggcgaa ccggatggca tgcccggtga tcgtggacgg
     9421 cgacagcctc gcctacctcg cgctgcgcag gatcgccgac gacccggtga cgttcgagtt
     9481 cggcgcgcac ggcttcggcc ccgacgaggg accgctggcc gccctgatca acaccgaggt
     9541 gcgcaagtgg gaccgcgagc accgcaccag cgacggcccg gtcttcaccg cccagccgat
     9601 cggcaccccc aacgaccagc tcccggacgg gctggtcgtc gacaagaccc acgtccgact
     9661 cacgatctcc tggccgtagt ccgcggccag gtcctgcacc accgactcaa ggaggaagca
     9721 ccatgagcac caccatcacc ggcaccgccg ccgcgagcga cttcgagctc gacgtgacga
     9781 tcgtcgaggg cgccgaccct gtggccgcgc tgctgcgctc caccgacgac ggctgcggca
     9841 gcacctgctc gggcaccgcc tgcacctcgt tcggtggcaa cgtctgaccg ttcctctccc
     9901 cgtgtgaccg gggcccggcg tgcggccgtc aagccgccgc acgccgggcc ccggcattcc
     9961 cgaaacctcc tgaaatcttc cggaatcgag gcgaataccc gtgtacgccg tcgcaggacc
    10021 ggccctgctg cgggccgccg cccgtccggc cgcggccggg ccgtcctggt ggcccgacct
    10081 ggccgacacc ggcccccacg ccaccgcgaa ctggcgggcc tggctccagc acgtctggtc
    10141 ggacgccgac ttcgcggcgg ccgtcgaggt cggagcgggc ccgcaactcg ccgcccgggt
    10201 acgcgaggtg gtcttcaact tcgaccacgt cccgaggcgg cggctgcgcc gcctgaccgc
    10261 ctcggtgatg cagtacgcgc tgcgccagca gcggcccacg cccttcgggc tgttcgccgg
    10321 ggtgaccgcg gtgcccttcg gcgaggtcgc cgccgcaccc cgctggggtg cgtcccgggt
    10381 ggtggcgcgg cccgatgcgc gctggctggc ctctgtggtg cgggagttgg aggaagcggt
    10441 cggtgacctg ctgccggtaa cggccaacca gctgcgggtg cggcgcgggg agcgcgtcgt
    10501 gctgccggtg acccgcaacc cgcaggacag cgaaccggcc gaggtgtccg tccgcgccac
    10561 cggcccggtg ctggccgtgc tggaagcggc cgacggcccg gtgtcggtga cgctcggcga
    10621 actcgccgac cgcttcccgg cagccccggc ggacaaggtc cgggcgatgc tcagcgagct
    10681 ggtgcgccag ggcttcctga tcagcatcct gcgactgccg accaccgtga ccgatccgct
    10741 cggtcacctg ctcgccatcg cccacaccac cggcctcgac cagatccccg ccgccgaagc
    10801 cacctggaac acccttcgaa cggtccgcga gcagctggcc cggcacaacg agctggacga
    10861 cccgacgaag cagcagacgc tgcgaacccg gttgacccgg cagctgaccc gccaaccggg
    10921 ctgggtcccg ggcggttcga cgccgctgat ggtggacctg cggctggacg ccggtcccgc
    10981 ggtgctaccg gagcgggtgg cgtcgctggt ggccggcgcg gccgaggtgc tgacgcggct
    11041 gtcgccgttc ccggacggcc atccggtgtg ggtggactac caccgccggt tcgcggagcg
    11101 gttcgggccg ggcgcggtgg tgccggtgct ggagttggtg aacccggaca ccgggatggg
    11161 cttccccgcc cgctaccggg actcggtgct gccggacgtg ccgccgcagt tcggacggcg
    11221 cgacgcccag cttctggcgc tggcgcagat ggccaccgtc gagcgcctgg accaggtcga
    11281 cctcaacggc ccgctgctgg agcgcctcgc cccggacccg gtgcccgacg gggcggtgca
    11341 accgcacgcc gagctgacgg tgcggctgtc ggcctacggt gtagggcctt tcacctacgg
    11401 ggccgcgcag ttcgcccccg tggtgcaggc ggtgccgcgc ggggcgggca cgaccgcggg
    11461 ccggttcctg tacctgctgg agcccgagcg ccgccgcgag ctggaggcgg cgatcaccgc
    11521 cgcgccgccg ctgcgggccg acgcgctggt ggtgcaggtc tccgcgcccc cgctgtacgc
    11581 ccgcgcagag aacgtctccc gggccccggc gctgctgccc ctgctggcac tgggggagta
    11641 cccgcagatc ggcgaagggc tgctgcggct ggaggagttg ggggtgtgcg cggacgagcg
    11701 gcggatgtgg ctggtgcggt tctccgaccg ccgcccggtg gaggtgcggg tcctcaacgc
    11761 ggtggacttc cgggcgaaca ccgacccgct ggtgcggttc ctgtgcgaga tcacccacgc
    11821 ccacaccccg tggctgaccg cgttcaactg gggagcggcc gggcagctgc cctacctacc
    11881 gcgggtgcgc tacggggagg tggtgctttc gccggcgcgc tggcacctgc ccgccgccga
    11941 cctcccgggc aaggacgccg actgggagga gtggagggcg gcggcgggcg agtggatcgc
    12001 ccggtacaac gtcccggcga cggtgtacct gtcgcagcag gacctgcggc tgccgctgga
    12061 cctgcgcgtg ccggagcacc tggtgctgct gcgcgatcac ctgctgcggg agccgaccgc
    12121 gatcctgatc gaggccccgc gggcagtcga caaccagtgg tgcggccggg cccacgaggt
    12181 caccgtgcag ctgcactcca cccgcacccc gctgcccgcc gcccgcccgc ggcccggcag
    12241 gccggtcacc gtccggtccg ggcacctgcc cggcgcgtcc gggtggctgt cggcccgcct
    12301 gttcggcaac ccgcgccgcg ccgacgaact cctcgcccgc gtacccgggt tggccgccgg
    12361 ttgggtggtc ccgccgcaat ggtggttcct gcggcacacc gaccccgagc cgcacgtgcg
    12421 cctgcgcatc ccggtctccg ccgtcgccgc gtggtcgctg gcctccgagc gcatcggccg
    12481 gtgggcggag cagatgcggg aggagggcct gctgacgcgg atggaactcg acacctacct
    12541 gccggagtcc ggccggtacg ggcgcggggc ggcgctacgg gcggcggagg agttcttctc
    12601 cctcgactcc cgcacggtgc tggcccaact cgcctaccag cgcgccacct ccaccgatcc
    12661 ggccaccatg acggcggcga gcatgctcga cctcgccacc gcgctgctgg gcagggaggc
    12721 cggccacgcc tggctgctgg agcgggtgcc caggcacagc aagatcgcgc tgccgcgctc
    12781 cgcatcgcgg ctggccgccg aactcgccga ccggcccgac cagttggaac tcaccgcgga
    12841 gggccgcctc ctctccctgg agtggcgggt gcgggccaag aagctggccg actaccgcag
    12901 ggcgctttgc cgggacgggg agttggagcc cgccgacgtc ctcggctcgc tgctgcacct
    12961 gcaccacgcc cgcgccgtcg gcctcaaccc ggccagcgag cgcacctgcc accgcctggc
    13021 ccgcgctgcc gcgctcaccc tcaccgcccg aaccgctcgc gccgaggaag gacaaccggc
    13081 atgaccgccg aactgctcgc accgcccgcc gaggtctccg cccagtgggg tcagtccctg
    13141 gccaagggcg gcctcgccac cgcgctgcta cacatcgagc gcgccgccac cggccggggg
    13201 agctgggaca ccgcgcacga gtggatcacc gcgtgcttga gccagcccgt gaactccttc
    13261 accggggcct ccgtgttcta cggcgcaccc gccgtcgccc acgtccttca cctggccgcg
    13321 ctccacggac cgcgcgccta ccaccagccg cgcatgctgc tggacaccgc ggtggagcac
    13381 gtggtggagc agcgcctggc cgccgcccac cgccgcatcg acgccgggca gcgccccgag
    13441 ttccacgagt tcgacctcct cggcgggctc accggtctcg gcgcgcacct gcgggtccga
    13501 ggccgccagg agctgctgag ggaagtgctg tcctacctgg tgtggctgac cgccccggtg
    13561 cacgggcgct cgggctggtg gacgcacctc gcgcccagcg gcgatccgga tgaccgctac
    13621 ccgggcgggc acggcaactt cggcatcgcg cacggcatcc ccggcccgct caccctgctg
    13681 gccctcacct acctcgacgg cacccgcgtc ccgggccagt tggaggcgat cgagcggatt
    13741 ctcgactggc tggacgcctg gcagcagaac ggcgccgccc gcgcctggtg gcccgaggcg
    13801 ctgaccgccg ccgaggccga tgagggccgg acccggcagt cgaagccgct gcgcccgtcc
    13861 tggtgctacg gaactcccgg catcgccacc gccctgcacc acgccgcccg caccatcggc
    13921 gaccccgacc gggcccgcac cgccgaagcc gctttcctcg acgcgatcga ggaccccgac
    13981 caggcccaca gcctcaccga cggcaccgtc tgccacggca ccgccggagt ccgcctggcc
    14041 gcccagcgct tcgccgaacg caccgacgac cacgccaccg ccctgcgcat tctcgccgcc
    14101 gccagcaacc tgcccgaccc cggcagcgac gccaccggcc acggcctgct cgaaggcacc
    14161 gccggcatcg ccctcacccg ctgctccctg gccgccgagt gccccggcgc tggctgggac
    14221 gccctgctgc tgctcatctg atccaaagga gaactctggt gcccgccacc ggcgaccaca
    14281 cctggacgca ggtccacctg cacctggcca ccgacacccc cgaagagcac gccgttcggc
    14341 tcctcggccc cgccctgata gccctggaag accaaggact gatcggctgc tggcacttcc
    14401 tgcgcaaggg cgaccgctgg cggctgcgct accgcgaggc cgcctccggc accctggagg
    14461 ccaccgccac cgcggccgcg gtcaacgagg tcctggacat gtgccgcgag gcgggcatga
    14521 tcagcgactg gaccccggcc atctacgagc cggagaccta cgtgttcggc ggggccgccg
    14581 cgctgcccgc cgctcaccgc ctcttccacc aggacagccg ccacgccctc acctacctca
    14641 ccgctgtgca ccgcggcgaa ctgtccgacc agcgagccga gttgtggctt ctgctcggca
    14701 cggccgcgat gcgcggtgcc ggactcgact ggtacgagat cggcgacacc tgggcgcagg
    14761 tcgccgagaa ccggtccgct gacggtcccg ggctggccgt cccagaccgc cgcctggtcg
    14821 acgccgcccg caccctgctg caggccgaca ccacccccgg ctccgcgctc ctggaaggcc
    14881 gactcgcgca cgccgcgtcc tggttcggcg cgttcgccgc ctacggcctg accctgcgga
    14941 cgctggccga cgagggccag ctgtggcgcg ggcagcgcgc cgtcctcgcc caccaccaac
    15001 tgttcaccgc gaaccgcctc ggcctgccct accaccagca ggccgctctt gcctccgccg
    15061 ctgccggtgc ggtcctggac ctggtcgagg ccaacgaggc ggtgctgcga tgagcgccca
    15121 gcgcactgca cagcccacgg gtccgctcgg cgacgccctc gcccgcctgc ccctcgtccc
    15181 ccgcaggcac gccctcgccg ccccgctgga gcagcgggtg caccagctca ccgacctcgc
    15241 ccggcaggcc accgacaccg agaacccggc cactgccgcc agcgtccaca accgcgccgc
    15301 gctgctcgcc tccgaccgcg gcctgccggg cctggcccgc gtgctgtgcc tcaaccacgc
    15361 cggcttctac ctcgcccgtc ggccgctgac cgtctacctg gcccgcctgg tcttcgagcc
    15421 cctcgtcaac ctcgcccacc tcgaactgcg ggcgggcaac ggcatcccgg cactcgcgat
    15481 cctggacgag ctgctgcgcg ccgtcgccga caacgacgac gccaccctcc ccggcggcct
    15541 gatcatcccc ctcgccgggc tgaccgccag cagcaccgac cgcgccgacg tccataagtg
    15601 gctcaccgac atccaggtct tcgagggcac ccgcgccctg gcccgcgccg ggcgctggac
    15661 cgaagctcac ttccacctca gacagtccac cgaccgcagc gaccgcctgt tcgagggccg
    15721 ccaggtcgcc gtcgtcgcca tggccttcga agggcgtacc gcactcgccc gtgccctggc
    15781 ccgcgacacc cccgccgaac agccgtggga gcacgccatc gccgccgccc tgaccgtcgc
    15841 gtgcacgctg ctcgacggcg acccggccgc cgatcaggcc gaggtgatgc tccgcgccca
    15901 cgccgccgtc accccgcgcc agggcagcga ggtgttcgac acccggctcg ccctgaccgt
    15961 cgctgacctc gccaccgccg ccggccgact ccccgacgcc gcccgcgtct acctcaccgc
    16021 cgtcggccgc accctcgccg accccgaggg ctacagcgcc cgcgacctcg cccgccaccg
    16081 cctcgccgac ggtctgcccg ccgaacagcg ccaccggctg gcagccatcg ccgccgagtg
    16141 cggcgtcggc ggcccggcca ccctgacgac cgaccacgac gaccggatca ccgccgccct
    16201 caccctggcc gccgccgtca tcaccaaggc cgccgccaag tccctctcgc cgtcgcggcc
    16261 gtgacccggc cgtccgttcg accgcggaca cgggcaccgc cgccggtccg gcgcactccc
    16321 cggcgcgcct tccagcagga cccgacaccg agaggcaacc gcatgagcaa taccctcacc
    16381 accgccaggc ccgagcccgg cgctctgggc tccttcgtcc acgtcggctg gaacatccag
    16441 cacggctgga agctgaccca agcgatcgat cacctgcgtc agttcgccca ggagcgcggc
    16501 gccgagcgcc cacacctgct caccctccag gaactccagg aggaccaggc cgccgaggtc
    16561 gcccagcagc tccagctgga cttcgtggag gcacccaacg agcgtcccgg cagccgcaac
    16621 gcgctgttct tcgcgcccga gctgttccag gccgaccccg agtggatccc ctacaccaac
    16681 gcggtccggc accggcccgc cacggccaaa ctgcgctgca tccaccccca caccggcgcc
    16741 ctcagcaagc gcgaggtctc ggtggcatcc gtccacctga acttcggcga ccccggcgac
    16801 cgcgagcacc agatccgctg gctgctggcc aacatgtaca aggaccggtg gctggccttc
    16861 ttccagggcg acatgaactc ctggccggtg tggggctgcc cgctccgcct cgacggggct
    16921 gaggacaagg catgggtggt ggaccgctcg atcgtcctgc ccgacggaac gacccggccc
    16981 gacgacgtgc ccgaccggct catgaccctc cgcggcatgg tcaacatcgg caggtacgcg
    17041 gccaccgtgc tcggacaggc cggcgcggac gggcccacca cctgggacgg tccgaagaag
    17101 gcccgtcagc ggatccccgg cgaagacctc ccgcccggca gcctcggcgg gatcgaccac
    17161 ggctacaccg ccgaggagct gatgcgggcg ctcatctccg caaccatccc gaacacgccg
    17221 caggtgcagg aggtttccga ccacctgccg caggtcaccg aatgggacac agaggtgtgg
    17281 tgggaagtga tggacgccga ggtcgagctc gtccgccact gatcctagga acggcgccgc
    17341 gccccgaaag cgaagatccc taccggtgct cggggttctc gaagtcgaaa cggcagcccg
    17401 cgtcccactc ggaccgctgg ttgccgtgca ccgggaggcc gcccgcgtcc ttcagcatcc
    17461 gcgccaggtg cagttggttc cacgtcatga acgtggtgtt ccggttggtg aagtcgttct
    17521 ccggcccgcc ggagccctcg tcgaggtacg acggccccgg gccggccggg ccgacccagc
    17581 ccgcatcggc ctgcggcggg atcgtgtacc ccaggtgctg gaggctgtag agcacgttca
    17641 tcgcgcagtg cttggcgccg tcctcgttgc cggtgatcag gcagccgccg acccggccgt
    17701 agtaggcgta ctggccgtgc tggttgagga ccgacgagca ggagtacagc cgctcgatga
    17761 cgcgcttcat gacggaggag ttgtctccca gccacacagg cccggctagc gtaaggatgt
    17821 cggcggccat caccttcgag tagatgaccg gccattcgtc gctctcccac ccgtgctctg
    17881 tcatgtccgg ccacacgccg gtcgcgatgt cgatgtcgac ggcacgaagg acttcgaccg
    17941 ccacgccttg gcgttccatg attcccgtgc tgatgtcgat gaggccttgg gtgtggctcc
    18001 gttccggcga tcgcttcagc gtgcagttga tcaccagggc tcgaaggtca ccgtacgacg
    18061 tgccaggcgc gggcatggct tcctctcctt cgactgctgc tcaggtcgtt cgggtcagct
    18121 caccagccac gggcccgacc ggctgacagg ctcacccggt cgggccgtga tcccgctcca
    18181 acggctcagc cgaggacgag caccggctcg tggtaggtca cttgcacgcc gtcggacgtc
    18241 tcgaagccgc gggactcgat cctgagctcg catcgcagcg acgcccggcc cccagagaac
    18301 gcccgcagta cgggttccag catcccggcc agcgtccacg acgaggtggc gaactcgaac
    18361 accccgagcg agggcgcctc ggtcagccgg aacgcgatct tgatctcggg cttcgcgccg
    18421 tggccggacc tggccgcaga gcgctgctcc gccaggcccg taccacggcc gcactgcttc
    18481 acttcgagag cagcagggcg gtgacaattc cggtgatccg cccggacctt gccactcccc
    18541 cgcacgcccc ggtgcaccat ccggaacgaa atcgactcag ccccgtgcat ggtgatcgag
    18601 agggagtggg ctccggtcct caccatgctg gcgggcgagg aaccgcgagg gtcagcttcg
    18661 tcgagcctgc cgcccagtgc cgaagcgacc gcaactgcgc tctctcggct gccggtgatg
    18721 aagcaccacc ctccctcggc catcacgctg atctgctcag cagccaccgg aagaccggac
    18781 ttcacacaac ggtacgtcgc cacaggacgc ctcctcacct ctcgtcgagt ggtgagagca
    18841 tccggatccg gcgcggtttg actcggccgt ccccccttgt ctcgaagccc agctcagccg
    18901 gggaccggcc cgccgcggcg tgacggcggc aggccagccg tgtcggtcag gctgccgcgg
    18961 cgaaggatcc ctggtccttc ggcttcaacc acgggtcggg ctggtcgagc cagtggatct
    19021 ccacgcgcga cgggccgtcg aacacgttgc atcctcgacg gcctttcgtc accacgaccc
    19081 ggcggatcac gaggcgcagc aactcgcgtc gcaggggcag gtcggcctct gcccaggcct
    19141 gccggatcgc ggcgtcctcc aggaggaacg agacgtcgag gcgcttcggg ctggcgtccg
    19201 ccaccctccg cttcgcgttc tccagggcgg tccgcgcctc ggcctgcagg accggcaggt
    19261 gcgtgtcgaa gggcgggtcg aagaagcccg aggcctgctg ttccaccagc cgcttgattc
    19321 cggcttcggc cgacttcaac gcggctgtgg cttcagcgag ttcagctccg ttgtccggct
    19381 gctggaggcc cttccagcgc tgggcggcct tcaccaggag caggtcgtcc ggctccgccg
    19441 cgttcatcca ggagaaccag gcttcggtca cgtactcctc gagccgtgcc cggctgaccg
    19501 acaccggcgc ggggcagaca tcgccctgta cggcgcgcca gcaccggtag ttctgcgagt
    19561 cgggggacgc accgctcctg cagccggggc acttcaccgc gtcggtgagg agttcgcggg
    19621 tcgtccccac ccgggcggcc tggtcggggg aggcgaaggt gaagccggcc gcgacctgcc
    19681 gggcccgggc gagcaggtcg gccggtacgg gttcgacacc ttcggcgagc acgctcaccc
    19741 ggttcccgtc gcggtcccgg aacgcctcga agcggccgcg ggtggccttc tgccgacggg
    19801 gcgccacctg ccagccctcg tagaccgggt tgtgcaggat ccgcgatatc gcgttcgcct
    19861 gccaccttcc gccgccgggc ccggggacgg ggttcgggcc ggagttgagc gccttggcca
    19921 cggatcgctg cgagaagccg agcgcgacgc acttgactac gtgcaggacg atccgccacg
    19981 tctcgggggc gtggcgcagt ttcctcgcct tgtccgcaca caggccgtag ggggccattt
    20041 gcgtccactg gccacgcgcc cgcatcgtcg ccttggtcga cttgatgttg tacgacaggc
    20101 ggttggagta ctcgcgggcc tgttcggcgc ggtcgatgat ccagcgccgg tcccgttcga
    20161 tcgaggagtc cagcccctcg tagtcgaaga tcacgcgggc cttgcccagg atcgggccga
    20221 tgtcgtcgat gcccttgcgg gtgaaccggt ccaggaaggc gcaccacagc gccggtactt
    20281 caccggccag gacggcggcc agcgccttgt cgaactcggg ccgctcgatg tcgctccagg
    20341 cggacaggtt gtccacccac acctcgcgga cccggcaccc ctcccgtgcg gcccaggccc
    20401 gaccggtgtt ctcctgggac tggatggagg tcaggtcacg cgggtcctcg tcgcggacga
    20461 cgcgcgattt gcgcaggtag aggtctacgt acggcaggtc ggtcatcact cgttctccgt
    20521 ccggggcggg ccatcatggc acgcgattgg cggcaggcag agtgttccgc cgactcagac
    20581 cgggccggcc agggtgagga tgtcggcgtt catgagctgc gagtagagga cgggccactc
    20641 gtcggtgtcc cagccgtgtt cggtcatgtc gggccagacg ccggtggcga tgtcgtggtc
    20701 gacggcgcgg atctcctcga cctggacgcc ctggcggcgc aggatgccgg cgctgatgtc
    20761 gatcaggccc tgggtgtggc tgcgttcggg gctgcgcttg agggtgcagt tgaggaagac
    20821 cgcccgcagg tcggtgtact gggtcatcgc cgtccgtccg ttcgtctcgt cgtctcgccg
    20881 ctgttccggc ggcccatcgc accacgcggg gggccggggg ccggggaccg tgcgccggac
    20941 ggcgccgtgt cgggggtagg ttcggagggc attggcacgt cgtcgtcgag aaggcaggtt
    21001 caggccatgg tggattcgtt gttcgagctc ccgatccgga cgctggcggg cgagccgtcc
    21061 tcgctgggcg agtaccggag ccaggtgctg ctgctggtga acgtggcgtc gaagtgcggg
    21121 ctgacgccgc agtacgcggg cctggagcgg ctgcaggaga agtacgggga gcgcgggttc
    21181 acggtgctcg ggttcccgtg caaccagttc atggggcagg agccggggtc ggcggaggag
    21241 atccaggagt tctgctcgac cacgtacggg gtgtcgttcc cgctgttcga gaagatcgac
    21301 gtgaacgggg cggagcggca cccgctgtac gcgcggctga ccgaggtcgc ggacgcgacc
    21361 ggcgaggccg gggacgtgca gtggaacttc gagaagttcc tggtgtcggc ggacggcgag
    21421 gtggtcgggc ggttccggcc gcggaccgag ccggagtcgg cggagctggt ggccgcgatc
    21481 gaggcgcagc tggcgggctg agcccgcgcg tggtgggccc ggggcccgga ccgtccgaac
    21541 tgtacaggta acctgcgcag tggaactgga cagtccgggc cccgggccgt ccgcgcagcc
    21601 gccccgacga aaggcccgcc gtgtccgtca ccgcgctcga cccgaacacc gccctggtcg
    21661 tcatcgacct ccagcagggc atcctcgcca tccccggcgc cccctacccg accaccgagg
    21721 tgctggcccg caacgtggcg ctggccgccg cgttccgcgc cgcgaagctg ccggtggtgc
    21781 tggtgcgggt gtccttcgcc accgacggag gggacgtgcc gcccggccgc accgagcaga
    21841 accgggccgg cggcgcggca ccccgcccgg agggctggga ccggctggcc gccgagctgc
    21901 acgacccgtc cgacctggtg gtcaccaagc acaactgggg cgccttccac ggcaccgacc
    21961 tggacgtgca gctgcgccgc cggggcgtca cccagatcgt gctgaccggc gtggccacca
    22021 gcatcggcgt ggagtccacc gcgcgggccg cgttcgagca cggctaccac gtgacgccgg
    22081 tggtcgacgc gatgaccgac atggacgcgg aggcccaccg ccacagcgtc gaacggatct
    22141 tcccgcggct gggcgagacc ggcaccaccg aggaggtgct ggcgctgctg gccgcggagc
    22201 gctgaggccc gccacgcagc accggagccc gtccgggccc ggccctcgac gggggtcggg
    22261 cccggacggg ctccggtgcg tgcagtgcgt gcggtgcgtg cagtgcgtgt ggtgcgcggt
    22321 acgcggtacg cggttcaggc ttcgccgggg cgccaggcgg gccactccca ggggcggtcg
    22381 tcccagtgca cccgggcggg gtcgtgcgga tcgaggtcgg ggaagtggtg gtgcagctcg
    22441 ggttcgaact cctcgggggc gagcggcttc cacccctcgc cctggaagtg gaccagccgg
    22501 tagcggctgt cggtgcggaa ctcggcgacc cggaccaggg gctcttcggc ggtgctgttg
    22561 ctcgtcatgc ggccagcatc ggccgggccg cggcacctcg cacgtccgca ccgccacccg
    22621 cgcgcaacgc gtcgccccgc ccagtccggc gcaccccgcc ccgcgcaccc cggcccggcc
    22681 cggcaccgcg gccgccccgg ggacgggggc gcggtcccgt accgtggagg ggaagtcggc
    22741 gggaacgttc gggaggaccg catgggcagg ggcaagggcc gggcggcccg ggtgcgcggg
    22801 ctggacgggg cggcggtggc gcgttcggcg tgggggctgt accgggagac ccggcggccg
    22861 ggtgcgcccg ggctcggggc gcgggcactg gcgctgcccc ggctgctgcg ggacgtgctg
    22921 gcggggcgct acccgggggt cgggccgggg aagctggcgg cgctgacggt ggcggtgggg
    22981 gtgtacctgc tcagtccggt ggacgcggtg ccggacttcc tgccgctgat cggctggggt
    23041 gacgacacgg cgctgctgct gtggttcctg atgggcctga cccgggagtc gggccggtac
    23101 ctggagtggg ccggcgaccg atcgccccgc aacgactgac tctcacttcg caagaatctg
    23161 acatctgcga gaaatttctg cgcaactctc ttgtggtgat gtggcgcgcg cccctactgt
    23221 cggctcactt ccaccacgcc tttcagagag ccggtccccg atgactgctg cccccgcatc
    23281 cccctcccgc tccgcgctgt cccgttcggc ccgcgcgggg gcggtggtcg tcgcctccgt
    23341 gctcgggctc ggggtggcgc tgtgcgcccc ggccgcgcag gccgcgcccg cctccggcgg
    23401 cgggggcgcc gcggtgaccc gggccgggat cgacccggcg ctgaccgcgg gccgcggcgc
    23461 ccgggtggac ttcctggagc aggaggccga gcacgccgcc accaccggca gcgtgatcgc
    23521 cgccgaccgc accgcgtaca ccctggccgc cgaggcgtcc ggccgcagcg cggtgaaact
    23581 ggccccgggc cagtacgtgg agttcaccct gccgaaggac gccaacgcga tcaccgtccg
    23641 ctacagcctc cccgacgcgg cggacggcgg cgggaccacc gccccgctgg acgtcaccgt
    23701 caacggcaag gaccggcggc agctctcggc caccagccag tactcctggc tgtacaacca
    23761 gtacccgttc agcaacgacc cgaaggccgg gctgctgcac ccggactggt ggatcaccga
    23821 gtgcggctgc gtgcccgccg ccaccacgcc cgcgcccgcg atcgccaccc cgttccggcc
    23881 cggccacatg tacgacgagc agcggctgct gctcggccgc acctaccggg cgggcgacaa
    23941 ggtgcggatc gcgctgcccg ccgggtcgaa ggccccgtgg gcggcgatcg acctgatgga
    24001 ctcccaactg gtggccgccc cgcacgtcga gctgaaggcc gtcaacgtgc tggcgaccgg
    24061 cgccgacccg accgggcggc gcgactccgc ggacgccatc gaccgggcgg tcaggctcgc
    24121 caaggccctg cacctgccgg tgtacctgcc gccgggcgtc ttccaggtca accggcacct
    24181 ggtggtcgac gacgtcaccg tgatcggcgc gggcagctgg tacaccgtgc tcaagggcac
    24241 ccagcagacc ctggccaccc ccgccccgga cggcagcgtg cacaccggcg tcggcgtcta
    24301 cggcaaggac gcggcgcagg gcggcagcca cgacgtccac ctgtccgggt tcgccatcga
    24361 gggcgacgtc cgggagcgga tcgacaccga ccaggtcaac ggcatcggcg gcgcgttcag
    24421 cgactccagc atcgagggcc tgtacatcca ccacaccaag gtcggcatct ggctggacgg
    24481 cccgatgaag aacctgcaga tcaccggcaa ccagatcgcc gaccagatcg ccgacggcat
    24541 caacttccac accggcgtgg ccgactcggt gatccgcgac aacttcctgc gcaacaccgg
    24601 cgacgacggc atcgcgctct ggtcggagaa gaccgcggac gcccgcaccg tcatcgacca
    24661 caacaccgtg cagtcgccga ccctggccaa cgccatcgcg gtgtacggcg gcaccgacac
    24721 caccgtctcg gacaacctgg tcgccgaccc ggtccgcgag ggctccggcc tgcacgccgg
    24781 ctcccggttc ggcgccgagc cgttcgccgg gtacctgcac ttcaccgaca acaccaccgt
    24841 gcgagccggc acctacgagc tgaactggaa catcggcctg ggcgcgatct ggttcgaggt
    24901 gctggaccgg gacatcgacg ccgacgtgcg ggtcaccggc gaccactacc tggactccac
    24961 ctacaacgcg atcatggcgg tcgccgagtg gggcgtgaag gaccagtaca agctgtccaa
    25021 cctggcgttc aaggacgtca agatcgacgg caccggcacc tcggtgctca gcgcccgggt
    25081 cgccgggtcg gccagcttcc agaacgtgac cgc
//
