LOCUS       NZ_JALAXV010000025     14751 bp    DNA     linear   CON 26-JAN-2024
DEFINITION  Bacillus inaquosorum strain T18B2 contig_0000025, whole genome
            shotgun sequence.
ACCESSION   NZ_JALAXV010000025
VERSION     NZ_JALAXV010000025.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus inaquosorum
  ORGANISM  Bacillus inaquosorum
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 14751)
  AUTHORS   Dunlap,C.
  TITLE     Crop Bioprotection Bacillus Genome Sequencing
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 14751)
  AUTHORS   Dunlap,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-FEB-2022) CBP, USDA-ARS-NCAUR, 1815 N. University St.,
            Peoria, IL 61604, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC NGS Cell v. 21
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 556.3003030959693x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/24/2024 02:40:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,343
            CDSs (total)                      :: 4,261
            Genes (coding)                    :: 4,152
            CDSs (with protein)               :: 4,152
            Genes (RNA)                       :: 82
            rRNAs                             :: 3, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2, 1 (5S, 16S)
            tRNAs                             :: 71
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 74 of 109
            Pseudo Genes (incomplete)         :: 58 of 109
            Pseudo Genes (internal stop)      :: 22 of 109
            Pseudo Genes (multiple problems)  :: 35 of 109
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:22:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 14751
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JALAXV010000025.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..14751
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     gene            <1..3750
                     /locus_tag="MOF15_RS21630"
                     /old_locus_tag="MOF15_21585"
     CDS             <1..3750
                     /NRPS_PKS="Domain: AMP-binding (191-596). E-value:
                     4.9e-100. Score: 326.9. Matches aSDomain:
                     nrpspksdomains_MOF15_RS21630_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (701-765). E-value: 8.7e-23. Score:
                     72.3. Matches aSDomain: nrpspksdomains_MOF15_RS21630_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (777-1088). E-value:
                     5.4e-143. Score: 469.4. Matches aSDomain:
                     nrpspksdomains_MOF15_RS21630_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (1097-1241). E-value: 1.9e-43.
                     Score: 139.9. Matches aSDomain:
                     nrpspksdomains_MOF15_RS21630_TIGR01720.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389716.2"
                     /locus_tag="MOF15_RS21630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOF15_21585"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_268284469.1"
                     /sec_met_domain="AMP-binding (E-value: 2.1e-110, bitscore:
                     356.8, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.4e-17, bitscore:
                     51.8, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 5.4e-87, bitscore:
                     279.3, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="AGRPHKDLEPILGMFVNTLALRTRPEGGKPFVEYLQEVRDTALGA
                     YEHQDYPFEELVDKLELTRDMSRNPVFDAMFILQNMEKQDMDLEEIKVQPANFAHHISL
                     FDITLIATETDGAICCELEFSTEVFLKATIERWAAHFIEFLHAALSNPETNLSQINILS
                     DKEKQNIVFEFNKTQVEFSQKDVPFHRIFEARAEETPEHIAVIDDETQISYQLLNERAN
                     RLARTLQKRKGTKPTVAVLAKRSIDAIVGILAVMKAGGVYIPIDSHYPKARIEYLLRDS
                     EADILLLQQELKHLISNSSECDISHICFDDESSYEENSCNLDLSPAPEDVAYIIYTSGT
                     TGAPKGVIVTYRNFTYAALAWRQIYELDRKPVRLLQMASFSFDVFSGDLARTLTNGGTL
                     IVCPDEKRLEPAELYGIMNSRRITIMESTPALIIPIMEYVYRNKLKLPDLDILILGSDM
                     VKAQDFKTLTERFGQSMRIINSYGVTEATIDSSCYETRMGEEYTGDNVPIGSPLPNVHM
                     YVLSQTNQIQPIGVAGELCISGAGVAKGYHNKPDLTQMKFTENPFVSGERLYRTGDRAC
                     WLPNGTIKLLGRMDYQVKINGYRIETEEIESVLLQTGLVREAAVAVQHDKNGHAGLAAY
                     IVPSDVSTNTLRAALTKELPAYMIPAHLIPIEKLPLTLNGKLDKNALPAPNDVFTRPYT
                     APVNDIQKTIAEIWEDVLSIARVGIHDSFFELGGDSIKALQVAARLAAEGWSMTIRDLF
                     RYPTIQELSGHITPLASQADQGPAEGEADLAPIQRRFFGQVHAFHYHYNQSVILFSEKG
                     FNTNALRRALRKITEHHDAIRMVFQRNQNGHVVQYNRGMNYNDHELFGLHIADWTKESL
                     ERTQFDEKLAAEEIGIQSKMNVQKGPLLQAGLFKTAEGDHLLIALHHLVIDGVSWRILL
                     EDLAAAYQQALEKQEIQLPPKTDSYLSYANGLAQIAENKQLLAEKSYWQSILDAHTAFL
                     PKDTENVPGRLQMNSDTAAFVLSGDWTEKLLFETQQAYGTNANELLLTALGMALSEWTG
                     HDQIVISTEGHGREGHVPNIDISRTVGWFTSIYPILLDMSIPEPFEDQLAFRIKTTKDM
                     LRRVPNKGTGYGLLTQIGELQYKEPEVSFNYLGQFSEEKEAETFQLSFYRPRYEIAGGR
                     EREYELDINALITDGRLQVKAVYTQVFSQHSIECFMDRFHRHLIEMIEHCSQKKIREKT
                     LSDFSNKELTLSALSSIEDLVKDL"
     source          1..14751
                     /db_xref="taxon:483913"
                     /mol_type="genomic DNA"
                     /organism="Bacillus inaquosorum"
                     /strain="T18B2"
                     /submitter_seqid="contig_0000025"
     cand_cluster    1..14751
                     /SMILES="NC(CCCN)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(C(O)C)C(=O)NC
                     (CCC(=O)O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..14751
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<0:>14751](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      <1..>14751
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     CDS_motif       4..69
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21630_0001"
                     /evalue="3.00E-09"
                     /label="C5_LCL_267-296"
                     /locus_tag="MOF15_RS21630"
                     /protein_end="22"
                     /protein_start="0"
                     /score="29.3"
                     /tool="antismash"
                     /translation="AGRPHKDLEPILGMFVNTLALR"
     CDS_motif       118..237
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21630_0002"
                     /evalue="2.30E-21"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="MOF15_RS21630"
                     /protein_end="78"
                     /protein_start="38"
                     /score="68.2"
                     /tool="antismash"
                     /translation="RDTALGAYEHQDYPFEELVDKLELTRDMSRNPVFDAMFIL"
     aSDomain        577..1791
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOF15_RS21630_AMP-binding.1"
                     /evalue="4.90E-100"
                     /label="MOF15_RS21630_AMP-binding.1"
                     /locus_tag="MOF15_RS21630"
                     /protein_end="596"
                     /protein_start="191"
                     /score="326.9"
                     /specificity="substrate consensus: Orn"
                     /tool="antismash"
                     /translation="FEARAEETPEHIAVIDDETQISYQLLNERANRLARTLQKRKGTKP
                     TVAVLAKRSIDAIVGILAVMKAGGVYIPIDSHYPKARIEYLLRDSEADILLLQQELKHL
                     ISNSSECDISHICFDDESSYEENSCNLDLSPAPEDVAYIIYTSGTTGAPKGVIVTYRNF
                     TYAALAWRQIYELDRKPVRLLQMASFSFDVFSGDLARTLTNGGTLIVCPDEKRLEPAEL
                     YGIMNSRRITIMESTPALIIPIMEYVYRNKLKLPDLDILILGSDMVKAQDFKTLTERFG
                     QSMRIINSYGVTEATIDSSCYETRMGEEYTGDNVPIGSPLPNVHMYVLSQTNQIQPIGV
                     AGELCISGAGVAKGYHNKPDLTQMKFTENPFVSGERLYRTGDRACWLPNGTIKLLGRMD
                     YQVKIN"
     aSModule        577..3726
                     /complete
                     /domains="nrpspksdomains_MOF15_RS21630_AMP-binding.1"
                     /domains="nrpspksdomains_MOF15_RS21630_PCP.1"
                     /domains="nrpspksdomains_MOF15_RS21630_Epimerization.1"
                     /domains="nrpspksdomains_MOF15_RS21630_TIGR01720.1"
                     /locus_tags="MOF15_RS21630"
                     /monomer_pairings="Orn -> D-Orn"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       760..801
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21630_0003"
                     /evalue="7.40E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="MOF15_RS21630"
                     /protein_end="266"
                     /protein_start="252"
                     /score="16.0"
                     /tool="antismash"
                     /translation="LAVMKAGGVYIPID"
     CDS_motif       997..1053
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21630_0004"
                     /evalue="2.40E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="MOF15_RS21630"
                     /protein_end="350"
                     /protein_start="331"
                     /score="26.2"
                     /tool="antismash"
                     /translation="AYIIYTSGTTGAPKGVIVT"
     CDS_motif       1585..1674
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21630_0005"
                     /evalue="8.50E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="MOF15_RS21630"
                     /protein_end="557"
                     /protein_start="527"
                     /score="46.9"
                     /tool="antismash"
                     /translation="PIGVAGELCISGAGVAKGYHNKPDLTQMKF"
     CDS_motif       1759..1821
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21630_0006"
                     /evalue="2.50E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="MOF15_RS21630"
                     /protein_end="606"
                     /protein_start="585"
                     /score="29.3"
                     /tool="antismash"
                     /translation="LGRMDYQVKINGYRIETEEIE"
     aSDomain        2107..2298
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOF15_RS21630_PCP.1"
                     /evalue="8.70E-23"
                     /label="MOF15_RS21630_PCP.1"
                     /locus_tag="MOF15_RS21630"
                     /protein_end="765"
                     /protein_start="701"
                     /score="72.3"
                     /tool="antismash"
                     /translation="KTIAEIWEDVLSIARVGIHDSFFELGGDSIKALQVAARLAAEGWS
                     MTIRDLFRYPTIQELSGHI"
     aSDomain        2335..3267
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOF15_RS21630_Epimerization.1"
                     /evalue="5.40E-143"
                     /label="MOF15_RS21630_Epimerization.1"
                     /locus_tag="MOF15_RS21630"
                     /protein_end="1088"
                     /protein_start="777"
                     /score="469.4"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLVIDG"
                     /tool="antismash"
                     /translation="EGEADLAPIQRRFFGQVHAFHYHYNQSVILFSEKGFNTNALRRAL
                     RKITEHHDAIRMVFQRNQNGHVVQYNRGMNYNDHELFGLHIADWTKESLERTQFDEKLA
                     AEEIGIQSKMNVQKGPLLQAGLFKTAEGDHLLIALHHLVIDGVSWRILLEDLAAAYQQA
                     LEKQEIQLPPKTDSYLSYANGLAQIAENKQLLAEKSYWQSILDAHTAFLPKDTENVPGR
                     LQMNSDTAAFVLSGDWTEKLLFETQQAYGTNANELLLTALGMALSEWTGHDQIVISTEG
                     HGREGHVPNIDISRTVGWFTSIYPILLDMS"
     CDS_motif       2440..2511
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21630_0007"
                     /evalue="1.40E-04"
                     /label="C2_LCL_024-062"
                     /locus_tag="MOF15_RS21630"
                     /protein_end="836"
                     /protein_start="812"
                     /score="14.3"
                     /tool="antismash"
                     /translation="FNTNALRRALRKITEHHDAIRMVF"
     CDS_motif       2737..2802
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21630_0008"
                     /evalue="2.50E-11"
                     /label="NRPS-E2"
                     /locus_tag="MOF15_RS21630"
                     /protein_end="933"
                     /protein_start="911"
                     /score="35.7"
                     /tool="antismash"
                     /translation="LLIALHHLVIDGVSWRILLEDL"
     CDS_motif       3208..3258
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21630_0009"
                     /evalue="4.40E-09"
                     /label="NRPS-E5"
                     /locus_tag="MOF15_RS21630"
                     /protein_end="1085"
                     /protein_start="1068"
                     /score="28.2"
                     /tool="antismash"
                     /translation="DISRTVGWFTSIYPILL"
     aSDomain        3295..3726
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOF15_RS21630_TIGR01720.1"
                     /evalue="1.90E-43"
                     /label="MOF15_RS21630_TIGR01720.1"
                     /locus_tag="MOF15_RS21630"
                     /protein_end="1241"
                     /protein_start="1097"
                     /score="139.9"
                     /tool="antismash"
                     /translation="AFRIKTTKDMLRRVPNKGTGYGLLTQIGELQYKEPEVSFNYLGQF
                     SEEKEAETFQLSFYRPRYEIAGGREREYELDINALITDGRLQVKAVYTQVFSQHSIECF
                     MDRFHRHLIEMIEHCSQKKIREKTLSDFSNKELTLSALSS"
     CDS_motif       3313..3369
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21630_0010"
                     /evalue="2.50E-08"
                     /label="NRPS-E6"
                     /locus_tag="MOF15_RS21630"
                     /protein_end="1122"
                     /protein_start="1103"
                     /score="26.2"
                     /tool="antismash"
                     /translation="TKDMLRRVPNKGTGYGLLT"
     aSDomain        3775..3858
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOF15_RS21635_NRPS-COM_Nterm.1"
                     /evalue="1.20E-15"
                     /label="MOF15_RS21635_NRPS-COM_Nterm.1"
                     /locus_tag="MOF15_RS21635"
                     /protein_end="28"
                     /protein_start="0"
                     /score="48.5"
                     /tool="antismash"
                     /translation="MAQSAQIQDIYPLSHMQEGMLFHSLMDV"
     gene            3775..11457
                     /locus_tag="MOF15_RS21635"
                     /old_locus_tag="MOF15_21590"
     CDS             3775..11457
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (0-28). E-value: 1.2e-15.
                     Score: 48.5. Matches aSDomain:
                     nrpspksdomains_MOF15_RS21635_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (7-309). E-value:
                     2.6e-110. Score: 360.2. Matches aSDomain:
                     nrpspksdomains_MOF15_RS21635_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (474-865). E-value:
                     3.1e-109. Score: 357.2. Matches aSDomain:
                     nrpspksdomains_MOF15_RS21635_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (970-1036). E-value: 3e-22. Score:
                     70.6. Matches aSDomain: nrpspksdomains_MOF15_RS21635_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1054-1341). E-value:
                     8.5e-106. Score: 345.2. Matches aSDomain:
                     nrpspksdomains_MOF15_RS21635_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1505-1903). E-value:
                     2.1e-117. Score: 384.1. Matches aSDomain:
                     nrpspksdomains_MOF15_RS21635_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2011-2078). E-value: 1.8e-20.
                     Score: 64.9. Matches aSDomain:
                     nrpspksdomains_MOF15_RS21635_PCP.2"
                     /NRPS_PKS="Domain: Epimerization (2088-2393). E-value:
                     1.2e-154. Score: 508.0. Matches aSDomain:
                     nrpspksdomains_MOF15_RS21635_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (2403-2553). E-value: 8.4e-53.
                     Score: 170.3. Matches aSDomain:
                     nrpspksdomains_MOF15_RS21635_TIGR01720.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389715.1"
                     /locus_tag="MOF15_RS21635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOF15_21590"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_268284470.1"
                     /sec_met_domain="Condensation (E-value: 8.5e-96, bitscore:
                     308.2, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 3.8e-127, bitscore:
                     411.9, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 7.1e-18, bitscore:
                     52.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQSAQIQDIYPLSHMQEGMLFHSLMDVSSKAYVEQTSFTITGNL
                     CIDSFQKSLNLLVSRYDIFRTIFIKEVQDLTGPQQIVLSNRELTVYREDFSHLADHEQQ
                     ALIDAFMTKDREKGFNLQKDPLMRLALFDRGNSQYTCIWTHHHIIMDGWCLGIILKEFF
                     SMYDSLKNNSPVRLGSTVPYSRYIEWLGEQDQEETAAYWSEYLKEYGNTATIPRINPRP
                     ADGDYKADQISFSLAPEMVEKLTEAAQNWGVTLNTLFMSMWGVLLHRYNATDDAVFGSV
                     ISGRPSAIDGIESMVGLFINTIPVRIRSAEGMTFSSLAKAVQEDILASEQHGYYPLYEI
                     QNHSPLKQGLIDHIFVFENYPVQLDQALSIESENEENALKLGDISMSEQTNYDFNIVIV
                     PGESFYIKFSYNAAVYEQEEMLRIQRHLKQALDCILAHPDIAVSDINIVPPEEQQVIQL
                     FNETERPYVNKTISQLFEEQARKTPEAAALKLGDDCWTYRQLNIRANQIAHALIEKGVG
                     SGDIVAVMMNRSMEKPAALLGIWKAGGAYMPLDPNFPEERLSFLLKDSQAAQLLIEENL
                     MSFIPPHYKGNMIMIEHTESHQTAAPDVPLGDLAYLIYTSGTTGRPKGVLVNHQGIANT
                     LQWRREEYGMTEQDISLHLFSYVFDGCVTSLFTPLISGACVLLTTDDEAKDVLALKRKI
                     ARYKVSHMIIVPSLYRVLLEVMTADDAKSLRIVTFAGEAVTPDLLEMSEKICPSAELAN
                     EYGPTENSVATTILRQLNEKERITIGHPIANTKVFVLHGNQMQPIGAAGELCISGTGLA
                     RGYYKQPELTEKAFSDHPFLEGERLYRTGDAGRFLPDGTIEYIGRFDDQVKIRGYRIEL
                     KEIETVLRQAPGVKEAAVLARDVSAEEKELVAYIVLEKGNNLPDLHRLLAGTLPPYMIP
                     ASFINISRMPLTSSGKLDRSALPEPENNASLTYMPPRTLIEADLAHIWGDVLNKQQIGI
                     RDDFFQLGGQSLKAAALVSRIHKKLNIELPISEVFSNPTVESMAVKLMSLKEHAFTQIE
                     PADQRDVYPLSFSQKRLYALHQLADDSTGYNMPAVLELRGNLDRQRLRSVLTELVNRHE
                     ALRTVFVLDRGEPVQIIHPEMAFDLKELEMESEQMLESAIESFIKPFDLSSGPLFRACV
                     ITMGNNRGFLLLDMHHIIADGVSMSTLVQEFTDLYCEKELPALNLHYKDFAVWQQEKYP
                     KELYKKQEAYWLDQLGGSLPVLELPLDKTRPRLPDFSGGTIEVNIDKDTADELHRLMVE
                     TGTTLYMILLAVYSILLSKLSGQEDIVVGSPAAGRPHADLERVIGMFVNTLAMRSQPEG
                     HKTFSSYLQDIRHLALTAYEHQDYPFEELADKLDTHREVNRNPLFDAMLVLQSSEDFQF
                     EVPGLSISSVTPKHDISKFDLTLHAEEHSGGIHCRFEYSTALFEEETIARWASHFIELV
                     KGVTADTKMRISEMQLLPAAERNLLLEKMGQYAAYPRNENIVSLFEKKAAEHPEHLAVV
                     YGHSQLTYRDLNEKAERTAAMLIKQGVRTGDIVGLMLDRSPDMIIGILSILKAGGAYLP
                     IDPEYPQERISFMLNDSGAEMLLTERGQNKPADYNGPIMYIDEGDSDSIPDDLNIQETL
                     SDQPAYVIYTSGTTGQPKGVIVEHRNVISLLKHQNLPFKFGHEDVWTFFHSYCFDFSVW
                     EMFGALLNGSTLVVVSKETARDPHAFRLLLKKERVTVLNQTPTAFYGLMHEDQNHTDRL
                     NIRYVIFGGEALQPGMLQSWNKKYPDTDLINMYGITETTVHVTFKKLSAADIAKNKSNI
                     GRPLSTLQAYVMDAHMNLQPIGVPGEMYIGGEGVARGYLNRDELTADRFVPNPYLPGDR
                     LYRTGDLAKRLSNGELEYLGRIDDQVKVRGHRIELGEIQAALLQLPAIKEAAVITRTDE
                     QGQAAVYAYIVTKDQQAANASEIRTSLKTMLPDFMLPARLIQIDSIPLTVNGKLDQKAL
                     PEPDKHGYIADDIRPRNEIEKVIAEIWEELLDVEELGVSANFFELGGDSIKALQVCARL
                     KQRGFETTVREMFEHQTLGELSARVRKAVHVIDQGPVEGEITWTPIQQWFFSQSLEINH
                     FNQSVMLYRTERFDETALKKVLKSLVTHHDALRIVCRYEDGRPVQINRGIDLPDKELYA
                     LELFDVKDNLTEAHNRIKEAASQMQEHLRLETGPLLHAGLFRTENGDHLFLTIHHLVVD
                     AVSWRILFEDFSTAYKQAVSGETIKLPQKTDSYLTYSQSIADYSKSRQMQREAAYWDER
                     ENRHIQPIPKDNEAAPNTFKDTEVIDFNLSRHHTELLLTAANKAYSTEMNDILLTALGL
                     ALQQWTGYDQFKISMEGHGRESYLEDIDISRTVGWFTSIYPVWLDMSHSDHKNKDERLG
                     HLIKQTKDMLHRIPHKGAGYGVLKYTNKKWDSEKGSPDISFNYLGQFDQDIQSKAFEVS
                     DIKPGNEISPNWERPHALDISGAVSSGCLNMHMIYNRLQFEKKTIQTFAEHFKQTLENI
                     IEHCTGKENREWSASDFTDEDLTLDELSEIMGAVNKL"
     aSDomain        3796..4701
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOF15_RS21635_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="2.60E-110"
                     /label="MOF15_RS21635_Condensation_DCL.1"
                     /locus_tag="MOF15_RS21635"
                     /protein_end="309"
                     /protein_start="7"
                     /score="360.2"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIIMDG"
                     /tool="antismash"
                     /translation="QDIYPLSHMQEGMLFHSLMDVSSKAYVEQTSFTITGNLCIDSFQK
                     SLNLLVSRYDIFRTIFIKEVQDLTGPQQIVLSNRELTVYREDFSHLADHEQQALIDAFM
                     TKDREKGFNLQKDPLMRLALFDRGNSQYTCIWTHHHIIMDGWCLGIILKEFFSMYDSLK
                     NNSPVRLGSTVPYSRYIEWLGEQDQEETAAYWSEYLKEYGNTATIPRINPRPADGDYKA
                     DQISFSLAPEMVEKLTEAAQNWGVTLNTLFMSMWGVLLHRYNATDDAVFGSVISGRPSA
                     IDGIESMVGLFINTIPVRIRS"
     aSModule        3796..6882
                     /complete
                     /domains="nrpspksdomains_MOF15_RS21635_Condensation_DCL.1"
                     /domains="nrpspksdomains_MOF15_RS21635_AMP-binding.1"
                     /domains="nrpspksdomains_MOF15_RS21635_PCP.1"
                     /locus_tags="MOF15_RS21635"
                     /monomer_pairings="Tyr -> Tyr"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       3805..3846
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21635_0001"
                     /evalue="9.00E-05"
                     /label="C1_DCL_004-017"
                     /locus_tag="MOF15_RS21635"
                     /protein_end="24"
                     /protein_start="10"
                     /score="14.5"
                     /tool="antismash"
                     /translation="YPLSHMQEGMLFHS"
     CDS_motif       3868..3981
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21635_0002"
                     /evalue="1.70E-14"
                     /label="C2_DCL_024-062"
                     /locus_tag="MOF15_RS21635"
                     /protein_end="69"
                     /protein_start="31"
                     /score="46.1"
                     /tool="antismash"
                     /translation="AYVEQTSFTITGNLCIDSFQKSLNLLVSRYDIFRTIFI"
     CDS_motif       4207..4272
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21635_0003"
                     /evalue="2.50E-11"
                     /label="C3_DCL_135-156"
                     /locus_tag="MOF15_RS21635"
                     /protein_end="166"
                     /protein_start="144"
                     /score="35.9"
                     /tool="antismash"
                     /translation="HHHIIMDGWCLGIILKEFFSMY"
     CDS_motif       4597..4692
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21635_0004"
                     /evalue="4.20E-19"
                     /label="C5_DCL_263-294"
                     /locus_tag="MOF15_RS21635"
                     /protein_end="306"
                     /protein_start="274"
                     /score="61.0"
                     /tool="antismash"
                     /translation="DAVFGSVISGRPSAIDGIESMVGLFINTIPVR"
     CDS_motif       4741..4857
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21635_0005"
                     /evalue="6.20E-20"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="MOF15_RS21635"
                     /protein_end="361"
                     /protein_start="322"
                     /score="63.7"
                     /tool="antismash"
                     /translation="QEDILASEQHGYYPLYEIQNHSPLKQGLIDHIFVFENYP"
     aSDomain        5197..6369
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOF15_RS21635_AMP-binding.1"
                     /evalue="3.10E-109"
                     /label="MOF15_RS21635_AMP-binding.1"
                     /locus_tag="MOF15_RS21635"
                     /protein_end="865"
                     /protein_start="474"
                     /score="357.2"
                     /specificity="substrate consensus: Tyr"
                     /tool="antismash"
                     /translation="FEEQARKTPEAAALKLGDDCWTYRQLNIRANQIAHALIEKGVGSG
                     DIVAVMMNRSMEKPAALLGIWKAGGAYMPLDPNFPEERLSFLLKDSQAAQLLIEENLMS
                     FIPPHYKGNMIMIEHTESHQTAAPDVPLGDLAYLIYTSGTTGRPKGVLVNHQGIANTLQ
                     WRREEYGMTEQDISLHLFSYVFDGCVTSLFTPLISGACVLLTTDDEAKDVLALKRKIAR
                     YKVSHMIIVPSLYRVLLEVMTADDAKSLRIVTFAGEAVTPDLLEMSEKICPSAELANEY
                     GPTENSVATTILRQLNEKERITIGHPIANTKVFVLHGNQMQPIGAAGELCISGTGLARG
                     YYKQPELTEKAFSDHPFLEGERLYRTGDAGRFLPDGTIEYIGRFDDQVKIR"
     CDS_motif       5383..5424
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21635_0006"
                     /evalue="6.80E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="MOF15_RS21635"
                     /protein_end="550"
                     /protein_start="536"
                     /score="16.1"
                     /tool="antismash"
                     /translation="LGIWKAGGAYMPLD"
     CDS_motif       5602..5661
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21635_0007"
                     /evalue="2.20E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="MOF15_RS21635"
                     /protein_end="629"
                     /protein_start="609"
                     /score="29.3"
                     /tool="antismash"
                     /translation="AYLIYTSGTTGRPKGVLVNH"
     CDS_motif       6034..6066
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21635_0008"
                     /evalue="1.20E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="MOF15_RS21635"
                     /protein_end="764"
                     /protein_start="753"
                     /score="5.7"
                     /tool="antismash"
                     /translation="EYGPTENSVAT"
     CDS_motif       6163..6252
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21635_0009"
                     /evalue="1.40E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="MOF15_RS21635"
                     /protein_end="826"
                     /protein_start="796"
                     /score="46.1"
                     /tool="antismash"
                     /translation="PIGAAGELCISGTGLARGYYKQPELTEKAF"
     CDS_motif       6334..6399
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21635_0010"
                     /evalue="2.70E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="MOF15_RS21635"
                     /protein_end="875"
                     /protein_start="853"
                     /score="35.4"
                     /tool="antismash"
                     /translation="YIGRFDDQVKIRGYRIELKEIE"
     aSDomain        6685..6882
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOF15_RS21635_PCP.1"
                     /evalue="3.00E-22"
                     /label="MOF15_RS21635_PCP.1"
                     /locus_tag="MOF15_RS21635"
                     /protein_end="1036"
                     /protein_start="970"
                     /score="70.6"
                     /tool="antismash"
                     /translation="EADLAHIWGDVLNKQQIGIRDDFFQLGGQSLKAAALVSRIHKKLN
                     IELPISEVFSNPTVESMAVKL"
     aSDomain        6937..7797
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOF15_RS21635_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="8.50E-106"
                     /label="MOF15_RS21635_Condensation_LCL.1"
                     /locus_tag="MOF15_RS21635"
                     /protein_end="1341"
                     /protein_start="1054"
                     /score="345.2"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIIADG"
                     /tool="antismash"
                     /translation="VYPLSFSQKRLYALHQLADDSTGYNMPAVLELRGNLDRQRLRSVL
                     TELVNRHEALRTVFVLDRGEPVQIIHPEMAFDLKELEMESEQMLESAIESFIKPFDLSS
                     GPLFRACVITMGNNRGFLLLDMHHIIADGVSMSTLVQEFTDLYCEKELPALNLHYKDFA
                     VWQQEKYPKELYKKQEAYWLDQLGGSLPVLELPLDKTRPRLPDFSGGTIEVNIDKDTAD
                     ELHRLMVETGTTLYMILLAVYSILLSKLSGQEDIVVGSPAAGRPHADLERVIGMFVNTL
                     AMRSQP"
     aSModule        6937..11433
                     /complete
                     /domains="nrpspksdomains_MOF15_RS21635_Condensation_LCL.1"
                     /domains="nrpspksdomains_MOF15_RS21635_AMP-binding.2"
                     /domains="nrpspksdomains_MOF15_RS21635_PCP.2"
                     /domains="nrpspksdomains_MOF15_RS21635_Epimerization.1"
                     /domains="nrpspksdomains_MOF15_RS21635_TIGR01720.1"
                     /locus_tags="MOF15_RS21635"
                     /monomer_pairings="Thr -> D-Thr"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       7006..7116
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21635_0011"
                     /evalue="2.80E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="MOF15_RS21635"
                     /protein_end="1114"
                     /protein_start="1077"
                     /score="55.1"
                     /tool="antismash"
                     /translation="YNMPAVLELRGNLDRQRLRSVLTELVNRHEALRTVFV"
     CDS_motif       7312..7377
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21635_0012"
                     /evalue="1.90E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="MOF15_RS21635"
                     /protein_end="1201"
                     /protein_start="1179"
                     /score="30.0"
                     /tool="antismash"
                     /translation="MHHIIADGVSMSTLVQEFTDLY"
     CDS_motif       7408..7443
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21635_0013"
                     /evalue="5.60E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="MOF15_RS21635"
                     /protein_end="1223"
                     /protein_start="1211"
                     /score="12.6"
                     /tool="antismash"
                     /translation="HYKDFAVWQQEK"
     CDS_motif       7699..7788
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21635_0014"
                     /evalue="8.90E-17"
                     /label="C5_LCL_267-296"
                     /locus_tag="MOF15_RS21635"
                     /protein_end="1338"
                     /protein_start="1308"
                     /score="53.4"
                     /tool="antismash"
                     /translation="DIVVGSPAAGRPHADLERVIGMFVNTLAMR"
     CDS_motif       7843..7956
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21635_0015"
                     /evalue="2.60E-14"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="MOF15_RS21635"
                     /protein_end="1394"
                     /protein_start="1356"
                     /score="45.5"
                     /tool="antismash"
                     /translation="LALTAYEHQDYPFEELADKLDTHREVNRNPLFDAMLVL"
     aSDomain        8290..9483
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOF15_RS21635_AMP-binding.2"
                     /evalue="2.10E-117"
                     /label="MOF15_RS21635_AMP-binding.2"
                     /locus_tag="MOF15_RS21635"
                     /protein_end="1903"
                     /protein_start="1505"
                     /score="384.1"
                     /specificity="substrate consensus: Thr"
                     /tool="antismash"
                     /translation="FEKKAAEHPEHLAVVYGHSQLTYRDLNEKAERTAAMLIKQGVRTG
                     DIVGLMLDRSPDMIIGILSILKAGGAYLPIDPEYPQERISFMLNDSGAEMLLTERGQNK
                     PADYNGPIMYIDEGDSDSIPDDLNIQETLSDQPAYVIYTSGTTGQPKGVIVEHRNVISL
                     LKHQNLPFKFGHEDVWTFFHSYCFDFSVWEMFGALLNGSTLVVVSKETARDPHAFRLLL
                     KKERVTVLNQTPTAFYGLMHEDQNHTDRLNIRYVIFGGEALQPGMLQSWNKKYPDTDLI
                     NMYGITETTVHVTFKKLSAADIAKNKSNIGRPLSTLQAYVMDAHMNLQPIGVPGEMYIG
                     GEGVARGYLNRDELTADRFVPNPYLPGDRLYRTGDLAKRLSNGELEYLGRIDDQVKVR"
     CDS_motif       8476..8517
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21635_0016"
                     /evalue="1.70E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="MOF15_RS21635"
                     /protein_end="1581"
                     /protein_start="1567"
                     /score="15.0"
                     /tool="antismash"
                     /translation="LSILKAGGAYLPID"
     CDS_motif       8701..8760
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21635_0017"
                     /evalue="4.50E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="MOF15_RS21635"
                     /protein_end="1662"
                     /protein_start="1642"
                     /score="31.4"
                     /tool="antismash"
                     /translation="AYVIYTSGTTGQPKGVIVEH"
     CDS_motif       9139..9162
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21635_0018"
                     /evalue="2.50E+00"
                     /label="NRPS-A_a5"
                     /locus_tag="MOF15_RS21635"
                     /protein_end="1796"
                     /protein_start="1788"
                     /score="2.0"
                     /tool="antismash"
                     /translation="YGITETTV"
     CDS_motif       9277..9366
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21635_0019"
                     /evalue="2.30E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="MOF15_RS21635"
                     /protein_end="1864"
                     /protein_start="1834"
                     /score="55.0"
                     /tool="antismash"
                     /translation="PIGVPGEMYIGGEGVARGYLNRDELTADRF"
     CDS_motif       9448..9513
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21635_0020"
                     /evalue="6.90E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="MOF15_RS21635"
                     /protein_end="1913"
                     /protein_start="1891"
                     /score="37.3"
                     /tool="antismash"
                     /translation="YLGRIDDQVKVRGHRIELGEIQ"
     aSDomain        9808..10008
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOF15_RS21635_PCP.2"
                     /evalue="1.80E-20"
                     /label="MOF15_RS21635_PCP.2"
                     /locus_tag="MOF15_RS21635"
                     /protein_end="2078"
                     /protein_start="2011"
                     /score="64.9"
                     /tool="antismash"
                     /translation="EKVIAEIWEELLDVEELGVSANFFELGGDSIKALQVCARLKQRGF
                     ETTVREMFEHQTLGELSARVRK"
     aSDomain        10039..10953
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOF15_RS21635_Epimerization.1"
                     /evalue="1.20E-154"
                     /label="MOF15_RS21635_Epimerization.1"
                     /locus_tag="MOF15_RS21635"
                     /protein_end="2393"
                     /protein_start="2088"
                     /score="508.0"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLVVDA"
                     /tool="antismash"
                     /translation="EGEITWTPIQQWFFSQSLEINHFNQSVMLYRTERFDETALKKVLK
                     SLVTHHDALRIVCRYEDGRPVQINRGIDLPDKELYALELFDVKDNLTEAHNRIKEAASQ
                     MQEHLRLETGPLLHAGLFRTENGDHLFLTIHHLVVDAVSWRILFEDFSTAYKQAVSGET
                     IKLPQKTDSYLTYSQSIADYSKSRQMQREAAYWDERENRHIQPIPKDNEAAPNTFKDTE
                     VIDFNLSRHHTELLLTAANKAYSTEMNDILLTALGLALQQWTGYDQFKISMEGHGRESY
                     LEDIDISRTVGWFTSIYPVWLDMS"
     CDS_motif       10054..10080
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21635_0021"
                     /evalue="2.90E-03"
                     /label="NRPS-E1"
                     /locus_tag="MOF15_RS21635"
                     /protein_end="2102"
                     /protein_start="2093"
                     /score="10.8"
                     /tool="antismash"
                     /translation="WTPIQQWFF"
     CDS_motif       10138..10203
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21635_0022"
                     /evalue="8.70E-03"
                     /label="C2_LCL_024-062"
                     /locus_tag="MOF15_RS21635"
                     /protein_end="2143"
                     /protein_start="2121"
                     /score="8.5"
                     /tool="antismash"
                     /translation="RFDETALKKVLKSLVTHHDALR"
     CDS_motif       10426..10491
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21635_0023"
                     /evalue="1.60E-11"
                     /label="NRPS-E2"
                     /locus_tag="MOF15_RS21635"
                     /protein_end="2239"
                     /protein_start="2217"
                     /score="36.3"
                     /tool="antismash"
                     /translation="LFLTIHHLVVDAVSWRILFEDF"
     CDS_motif       10894..10944
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21635_0024"
                     /evalue="5.10E-09"
                     /label="NRPS-E5"
                     /locus_tag="MOF15_RS21635"
                     /protein_end="2390"
                     /protein_start="2373"
                     /score="28.0"
                     /tool="antismash"
                     /translation="DISRTVGWFTSIYPVWL"
     aSDomain        10984..11433
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOF15_RS21635_TIGR01720.1"
                     /evalue="8.40E-53"
                     /label="MOF15_RS21635_TIGR01720.1"
                     /locus_tag="MOF15_RS21635"
                     /protein_end="2553"
                     /protein_start="2403"
                     /score="170.3"
                     /tool="antismash"
                     /translation="LGHLIKQTKDMLHRIPHKGAGYGVLKYTNKKWDSEKGSPDISFNY
                     LGQFDQDIQSKAFEVSDIKPGNEISPNWERPHALDISGAVSSGCLNMHMIYNRLQFEKK
                     TIQTFAEHFKQTLENIIEHCTGKENREWSASDFTDEDLTLDELSEI"
     CDS_motif       11005..11064
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21635_0025"
                     /evalue="5.20E-08"
                     /label="NRPS-E6"
                     /locus_tag="MOF15_RS21635"
                     /protein_end="2430"
                     /protein_start="2410"
                     /score="25.2"
                     /tool="antismash"
                     /translation="TKDMLHRIPHKGAGYGVLKY"
     gene            11477..>14751
                     /locus_tag="MOF15_RS21640"
                     /old_locus_tag="MOF15_21595"
     CDS             11477..>14751
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (2-30). E-value: 2.6e-16.
                     Score: 50.5. Matches aSDomain:
                     nrpspksdomains_MOF15_RS21640_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (7-305). E-value:
                     3e-116. Score: 379.7. Matches aSDomain:
                     nrpspksdomains_MOF15_RS21640_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (469-870). E-value: 1e-111.
                     Score: 365.4. Matches aSDomain:
                     nrpspksdomains_MOF15_RS21640_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (972-1041). E-value: 2.1e-26. Score:
                     83.9. Matches aSDomain: nrpspksdomains_MOF15_RS21640_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389714.1"
                     /locus_tag="MOF15_RS21640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOF15_21595"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_268284471.1"
                     /sec_met_domain="Condensation (E-value: 4.3e-93, bitscore:
                     299.3, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.5e-123, bitscore:
                     400.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.2e-17, bitscore:
                     52.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQQPEIQDIYPLSFMQEGMLFHSLYDEQSRAYFEQASFTIHGQL
                     DLERFQKSMDAVFERYEIFRTAFIYKNVAKPRQVVLKHRHCHVHFEDISHLNERDKEHC
                     TEAFKEQDKSRGFDLQTDVLMRISILKWAPNRYVCIWSHHHILMDGWCLGIVIKDFLHI
                     YQALGKGQLPDLHPVQSYGTYIKWLMQQDREEAAEYWKKRLQHFEKATPLPKRTDQIPD
                     GTLEQITFTISEKETSELQKIAAASGATLNTVFQALWGIMLQKFNRCGDAVFGSVISGR
                     TSELRDVENMVGLFINTIPIRVQSDSLSFSDLVSRMQRDMTEAEAYSYFPLYDIQAQSA
                     LKQELIDHIIVFENTPTQQEIEGLNQAGSFDFSVKDFDMEEVTNYSCSVKVIPGRTLYV
                     RIHFHTGAYQPSMMSEIKDYLQHMVSDVISDPSLPVSKMTLLDENKTRKIVSQNNGAVS
                     VSPEAPTLHGLFERQAAFTPERPAIRFSSGSLTYAELDMYASRLAARLAARGVTKESIV
                     GVLSERSPEMLIAVLAVLKAGGAYLPLDPAYPKERLSYMLKDSGAALLLAQPGCSAPGF
                     SGEMLEVDMASLASEKAENDVFTPADGCSLAYVIYTSGSTGKPKGVAVEHRQAVSFLTG
                     MQRQFPLQEDDIVMVKTSFSFDASVWQLFWWSLSGASAYLLPPGWEKDPALIVKAIHQE
                     KVTTAHFIPAMLNSFLDQAEMKALGDGTSLKRVFAGGEPLAPHVAARFASLLPQVSLIH
                     GYGPTEATVDAAFYVLDPGRDRDRLRIPIGKPVPGARLYVLDAHLAVQPCGVAGELYIA
                     GAGVARGYLNRPALTEERFLEDPFYPGERMYKTGDLARWLPEGHVEFLGRLDDQVKIRG
                     YRIEPGEIEAVLRGIEGIREAAVTVRTDSGEPELCAYTEGLRRNEVRTQLERLLPSYMI
                     PAHMIEMERWPVTPSGKLDRNALPAPGGAADEEAYTAPRNVTEMKLAQLWEDVLKNGPV
                     GIHDNFFDRGGHSLKATALVSRIAKEFDVQVPLKDVFAHPTVEGLASVIREGTDSPYEA
                     MKLAEKREAYPVSSAQKRIYVLQQLEDGGIGYNMPAMLELEGKL"
     aSDomain        11483..11566
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOF15_RS21640_NRPS-COM_Nterm.1"
                     /evalue="2.60E-16"
                     /label="MOF15_RS21640_NRPS-COM_Nterm.1"
                     /locus_tag="MOF15_RS21640"
                     /protein_end="30"
                     /protein_start="2"
                     /score="50.5"
                     /tool="antismash"
                     /translation="QQPEIQDIYPLSFMQEGMLFHSLYDEQS"
     aSDomain        11498..12391
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOF15_RS21640_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="3.00E-116"
                     /label="MOF15_RS21640_Condensation_DCL.1"
                     /locus_tag="MOF15_RS21640"
                     /protein_end="305"
                     /protein_start="7"
                     /score="379.7"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHILMDG"
                     /tool="antismash"
                     /translation="QDIYPLSFMQEGMLFHSLYDEQSRAYFEQASFTIHGQLDLERFQK
                     SMDAVFERYEIFRTAFIYKNVAKPRQVVLKHRHCHVHFEDISHLNERDKEHCTEAFKEQ
                     DKSRGFDLQTDVLMRISILKWAPNRYVCIWSHHHILMDGWCLGIVIKDFLHIYQALGKG
                     QLPDLHPVQSYGTYIKWLMQQDREEAAEYWKKRLQHFEKATPLPKRTDQIPDGTLEQIT
                     FTISEKETSELQKIAAASGATLNTVFQALWGIMLQKFNRCGDAVFGSVISGRTSELRDV
                     ENMVGLFINTIPIRVQS"
     aSModule        11498..14599
                     /complete
                     /domains="nrpspksdomains_MOF15_RS21640_Condensation_DCL.1"
                     /domains="nrpspksdomains_MOF15_RS21640_AMP-binding.1"
                     /domains="nrpspksdomains_MOF15_RS21640_PCP.1"
                     /locus_tags="MOF15_RS21640"
                     /monomer_pairings="Glu -> Glu"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       11507..11548
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21640_0001"
                     /evalue="6.70E-05"
                     /label="C1_DCL_004-017"
                     /locus_tag="MOF15_RS21640"
                     /protein_end="24"
                     /protein_start="10"
                     /score="14.8"
                     /tool="antismash"
                     /translation="YPLSFMQEGMLFHS"
     CDS_motif       11570..11686
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21640_0002"
                     /evalue="4.80E-18"
                     /label="C2_DCL_024-062"
                     /locus_tag="MOF15_RS21640"
                     /protein_end="70"
                     /protein_start="31"
                     /score="57.4"
                     /tool="antismash"
                     /translation="AYFEQASFTIHGQLDLERFQKSMDAVFERYEIFRTAFIY"
     CDS_motif       11903..11968
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21640_0003"
                     /evalue="7.20E-11"
                     /label="C3_DCL_135-156"
                     /locus_tag="MOF15_RS21640"
                     /protein_end="164"
                     /protein_start="142"
                     /score="34.5"
                     /tool="antismash"
                     /translation="HHHILMDGWCLGIVIKDFLHIY"
     CDS_motif       12287..12382
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21640_0004"
                     /evalue="8.60E-19"
                     /label="C5_DCL_263-294"
                     /locus_tag="MOF15_RS21640"
                     /protein_end="302"
                     /protein_start="270"
                     /score="59.9"
                     /tool="antismash"
                     /translation="DAVFGSVISGRTSELRDVENMVGLFINTIPIR"
     CDS_motif       12428..12544
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21640_0005"
                     /evalue="9.70E-19"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="MOF15_RS21640"
                     /protein_end="356"
                     /protein_start="317"
                     /score="59.8"
                     /tool="antismash"
                     /translation="QRDMTEAEAYSYFPLYDIQAQSALKQELIDHIIVFENTP"
     aSDomain        12884..14086
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOF15_RS21640_AMP-binding.1"
                     /evalue="1.00E-111"
                     /label="MOF15_RS21640_AMP-binding.1"
                     /locus_tag="MOF15_RS21640"
                     /protein_end="870"
                     /protein_start="469"
                     /score="365.4"
                     /specificity="substrate consensus: Glu"
                     /tool="antismash"
                     /translation="FERQAAFTPERPAIRFSSGSLTYAELDMYASRLAARLAARGVTKE
                     SIVGVLSERSPEMLIAVLAVLKAGGAYLPLDPAYPKERLSYMLKDSGAALLLAQPGCSA
                     PGFSGEMLEVDMASLASEKAENDVFTPADGCSLAYVIYTSGSTGKPKGVAVEHRQAVSF
                     LTGMQRQFPLQEDDIVMVKTSFSFDASVWQLFWWSLSGASAYLLPPGWEKDPALIVKAI
                     HQEKVTTAHFIPAMLNSFLDQAEMKALGDGTSLKRVFAGGEPLAPHVAARFASLLPQVS
                     LIHGYGPTEATVDAAFYVLDPGRDRDRLRIPIGKPVPGARLYVLDAHLAVQPCGVAGEL
                     YIAGAGVARGYLNRPALTEERFLEDPFYPGERMYKTGDLARWLPEGHVEFLGRLDDQVK
                     IR"
     CDS_motif       13070..13111
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21640_0006"
                     /evalue="6.80E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="MOF15_RS21640"
                     /protein_end="545"
                     /protein_start="531"
                     /score="19.1"
                     /tool="antismash"
                     /translation="LAVLKAGGAYLPLD"
     CDS_motif       13295..13354
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21640_0007"
                     /evalue="3.00E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="MOF15_RS21640"
                     /protein_end="626"
                     /protein_start="606"
                     /score="35.0"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGKPKGVAVEH"
     CDS_motif       13880..13969
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21640_0008"
                     /evalue="8.40E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="MOF15_RS21640"
                     /protein_end="831"
                     /protein_start="801"
                     /score="56.4"
                     /tool="antismash"
                     /translation="PCGVAGELYIAGAGVARGYLNRPALTEERF"
     CDS_motif       14051..14116
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF15_RS21640_0009"
                     /evalue="5.70E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="MOF15_RS21640"
                     /protein_end="880"
                     /protein_start="858"
                     /score="40.6"
                     /tool="antismash"
                     /translation="FLGRLDDQVKIRGYRIEPGEIE"
     aSDomain        14393..14599
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOF15_RS21640_PCP.1"
                     /evalue="2.10E-26"
                     /label="MOF15_RS21640_PCP.1"
                     /locus_tag="MOF15_RS21640"
                     /protein_end="1041"
                     /protein_start="972"
                     /score="83.9"
                     /tool="antismash"
                     /translation="EMKLAQLWEDVLKNGPVGIHDNFFDRGGHSLKATALVSRIAKEFD
                     VQVPLKDVFAHPTVEGLASVIREG"
ORIGIN
        1 gccggccggc cgcacaagga tcttgagccg atactcggca tgtttgtgaa cacgctggcg
       61 ctgcggacac gcccggaggg cgggaagccg tttgtggagt atttgcagga agtgcgcgac
      121 acagcattgg gagcctacga gcatcaggat tatccgttcg aagagctcgt cgacaagctt
      181 gaattgacgc gggatatgag ccggaatcca gtttttgatg cgatgtttat ccttcaaaat
      241 atggaaaagc aggacatgga tctggaagag ataaaagtcc agcccgccaa tttcgcacat
      301 cacatttctt tattcgatat cacactaata gcaacggaaa cagatggagc tatttgctgc
      361 gaattggaat ttagtacaga agtattcctg aaagctacga ttgagcgctg ggcagctcat
      421 tttatcgaat ttctgcatgc ggcactttct aatcctgaaa caaacctttc acaaataaac
      481 attcttagtg ataaagaaaa acaaaatata gtctttgaat tcaacaaaac tcaagttgaa
      541 ttttctcaaa aagatgttcc ttttcatcgc atatttgaag cgagagctga agaaacacca
      601 gaacatatag ctgttattga tgacgaaaca cagattagtt atcagcttct aaacgaaaga
      661 gccaatcgac tggcacggac gttgcaaaaa agaaaaggga cgaagccaac tgtggctgtt
      721 ttagccaagc ggtccattga tgcaattgtt ggaatcctag cagtgatgaa agctggcgga
      781 gtgtatatcc caatcgattc acattatcca aaagctagaa ttgaatacct tctccgtgat
      841 agcgaagcag acattcttct tttgcagcag gagttgaagc atttgatttc aaactcatct
      901 gaatgtgata tatctcacat ctgctttgat gatgagagct cttatgaaga aaacagctgc
      961 aaccttgact tatctcctgc tcctgaggat gtagcataca tcatttatac gtcaggaact
     1021 acgggcgcgc ctaaaggcgt tattgtcacc tatcggaact ttacctatgc agctcttgct
     1081 tggcggcaaa tttatgaact ggatcggaag cctgtcagac tgctccaaat ggcgagcttt
     1141 tcatttgatg tcttttcagg agatttagcg agaacattga ccaacggtgg gactctaatc
     1201 gtttgcccag atgaaaagcg gctggaacct gctgaattat atggaatcat gaactctcgg
     1261 cgaatcacga taatggagtc aacgccggct ctcattatcc caattatgga gtatgtatac
     1321 cgtaacaagc tcaagcttcc tgacttagac atattgattc ttggttccga catggtgaaa
     1381 gctcaagatt tcaaaacatt gacagaacgc tttggccaaa gcatgcgcat cattaatagt
     1441 tatggcgtca cagaagcgac gatcgattcc agctgctatg aaacaaggat gggagaagag
     1501 tatacgggag ataacgtccc aattggcagt ccgctaccga atgtacacat gtacgtactc
     1561 agccagacta atcaaattca gccgattggc gttgccggcg agctatgcat cagcggagca
     1621 ggtgttgcga aaggctatca taataaacct gacttaacgc aaatgaaatt tacagaaaat
     1681 ccatttgtct ccggagaaag gctgtacaga accggtgatc gagcctgctg gcttccaaac
     1741 ggaacgatca agcttcttgg ccgaatggat tatcaggtga agataaatgg atacagaatt
     1801 gaaacagaag aaattgaaag tgttctgctt caaaccgggc tggtcagaga agctgctgtt
     1861 gccgttcagc atgataagaa tggacatgct ggtttagcag catatattgt gccttcagac
     1921 gtcagtacga atactctccg tgctgcttta acaaaggagc tgccggcata tatgattcct
     1981 gcgcatctga ttcctataga aaaactgccg ctgaccctaa acggaaagct ggacaaaaac
     2041 gccttgccgg ctccaaatga tgtgttcaca cgtccatata cggcaccagt taacgacata
     2101 caaaaaacga tagcggaaat atgggaagat gtcctgtcca ttgctcgagt cggcattcac
     2161 gattcctttt ttgagcttgg cggagactca ataaaagcat tacaagtggc agcacggctg
     2221 gccgctgaag gctggagcat gacaatacgt gacttattcc gttatccaac gattcaggag
     2281 ctaagcggac atatcacacc attggcatct caagctgatc agggacctgc ggaaggtgaa
     2341 gctgatctcg ccccgattca gcgaagattt ttcggacagg ttcatgcttt tcactaccat
     2401 tacaaccagt ccgtcatact tttcagtgaa aaaggattca atactaatgc gcttcgtcgg
     2461 gcgctgcgta aaataaccga gcatcacgat gcaattcgca tggtttttca acgaaatcaa
     2521 aacggccatg tcgttcagta taatcgcgga atgaattaca acgatcatga actgttcggc
     2581 cttcacatag cagactggac aaaagaatca ctggaaagga ctcagtttga tgaaaaacta
     2641 gccgctgagg aaatcggcat tcaaagcaaa atgaatgtac aaaaagggcc tctgctgcaa
     2701 gcaggtttgt ttaaaacggc agaaggggac catttgctga ttgcgcttca tcatcttgtg
     2761 atagatggcg tttcttggag aatactgctt gaggatttag ctgcagcata ccagcaggct
     2821 ttagaaaaac aagagatcca attaccgcca aaaacggatt cttatttgtc ctacgccaat
     2881 ggtcttgcac aaattgctga aaacaaacaa ttgcttgcag aaaaatcata ttggcaatca
     2941 attttggacg ctcacactgc ttttctgcct aaggacacgg aaaatgtgcc aggaagactg
     3001 caaatgaaca gcgatacagc ggcgtttgta ctatccgggg actggactga aaaattgctg
     3061 tttgaaaccc agcaagccta tggcactaat gccaacgaac ttttgcttac ggcgttagga
     3121 atggcgcttt ctgaatggac aggacatgac caaatcgtga ttagcactga gggacacggt
     3181 agagaggggc atgtgccaaa cattgatatt tcacggacag ttggatggtt tacttccatt
     3241 tatcctattc tgctggacat gagtattccc gagcctttcg aggatcagct cgcattccga
     3301 attaagacga caaaagatat gctgagaagg gtaccgaaca aaggaactgg ttacggattg
     3361 ttaacacaga taggagaact gcagtataaa gagcctgagg tcagctttaa ttatctcggc
     3421 caattcagcg aagagaagga agctgaaacg tttcaattat cattttaccg gcctcgttac
     3481 gaaatagcgg gtgggagaga acgagagtat gagctggaca tcaatgctct tattacagac
     3541 ggacggcttc aagtaaaagc ggtatacacc caagtgttca gccaacactc aattgagtgt
     3601 tttatggatc gttttcacag gcatcttatc gagatgattg agcattgttc tcagaaaaaa
     3661 atacgcgaaa aaacgctgag tgatttcagc aataaggaat taacgttgtc tgcattatct
     3721 agcatcgaag atctcgtgaa agatctttaa cttttgaaaa ggtgtgtgga attgatggca
     3781 caatcggcac agattcaaga tatttatccg ttatcgcaca tgcaggaagg aatgctgttt
     3841 cattcactga tggatgtcag ctcaaaagcc tatgtcgaac agacctcgtt tacgatcaca
     3901 gggaatctat gcatcgactc gtttcaaaag agcttaaacc ttcttgtttc ccggtatgat
     3961 attttcagaa cgatttttat taaagaagtc caagatctta caggtccgca gcagatagtc
     4021 ctgtcaaacc gggaattgac agtgtataga gaagattttt ctcacctggc cgatcatgaa
     4081 cagcaggctc tgatcgatgc ttttatgacc aaggatcggg aaaaaggatt taatttgcaa
     4141 aaagatccgt taatgcgtct tgcccttttt gatagaggca acagccaata tacatgtatc
     4201 tggacacatc accatatcat catggatggc tggtgtctcg gcattattct taaagagttt
     4261 ttcagcatgt atgattcgct caaaaataac tcacctgtac ggcttggcag cacggtaccg
     4321 tacagccgct atattgaatg gctcggagaa caagatcaag aagagactgc tgcttactgg
     4381 agcgaatatt tgaaggagta cggcaatact gcaactatcc cccggataaa tccccgcccg
     4441 gcggacgggg attataaagc cgaccagatc agcttttctt tagcaccgga aatggttgag
     4501 aaactgactg aggccgccca aaattgggga gtgacattaa acacgttgtt tatgagtatg
     4561 tggggcgtgc tcctccatcg atataatgcc acagatgacg cagtttttgg ctccgtcatt
     4621 tcgggacgcc cgtcagcgat tgacggtatt gaatcaatgg tcggcttgtt tattaatact
     4681 atcccagtgc gaattcgatc tgcggagggt atgacgtttt cttcgctggc caaagccgtg
     4741 caggaggata ttttagcatc tgaacagcat gggtattatc cgctttatga aattcaaaac
     4801 catagtccat tgaagcaagg gttgatcgat catatttttg tctttgaaaa ttatcctgta
     4861 cagcttgatc aggcgttaag cattgagagt gaaaacgagg aaaatgcact gaagcttggt
     4921 gacatttcaa tgtccgaaca aaccaattac gactttaata tcgttattgt tccgggagaa
     4981 tcattttata tcaaattcag ctacaacgca gccgtttatg aacaggagga gatgctgagg
     5041 attcagaggc atctaaaaca agctctagat tgcattttgg cacatcccga tattgccgtc
     5101 agtgacatca atatcgtccc gccggaggag caacaggtta tccaattgtt taacgaaact
     5161 gagcgtcctt atgtgaacaa aacgatatcc caattgttcg aggaacaagc ccgcaaaaca
     5221 cctgaagctg ctgcattaaa attgggagac gattgctgga cctatcgcca attaaatata
     5281 agagccaatc agattgcgca cgccctgata gaaaaaggcg ttggatctgg agatatcgtg
     5341 gctgtgatga tgaaccggtc aatggaaaag cctgcagctc tacttgggat ttggaaagca
     5401 ggcggcgctt atatgccgct tgatccaaat ttcccagaag aacgtctttc ttttctgctg
     5461 aaggacagtc aagcagctca attgctgata gaagaaaacc ttatgtcatt catcccgccg
     5521 cactataaag gaaatatgat aatgatagaa catacagaaa gtcaccaaac agcagctcca
     5581 gatgtgccgc ttggtgatct cgcctatttg atctatacgt cgggaacgac agggcgccct
     5641 aaaggtgttc tagttaatca tcaaggcatt gccaatacat tgcaatggag acgggaagag
     5701 tatggcatga ccgaacagga tatatccctc catttgtttt catatgtgtt tgacggttgt
     5761 gtgacgagct tgtttacccc gcttatatcc ggtgcgtgcg tattgctgac aacggatgac
     5821 gaagcgaagg atgtgctagc ccttaaacga aaaatagccc gttataaggt cagtcacatg
     5881 atcattgttc cttccctgta ccgggtgtta ttggaagtga tgactgctga cgatgcaaaa
     5941 agtcttcgta ttgtgacatt cgctggtgaa gcggtcacgc ctgacctgct tgagatgagc
     6001 gaaaagattt gtccttctgc agaattggca aatgaatacg ggcccacaga aaatagtgtg
     6061 gcaacaacaa tattgcgtca actgaacgaa aaagagagga tcacgatcgg acacccgatt
     6121 gcgaacacaa aagtatttgt tttacacgga aatcaaatgc agccgatcgg cgcggcgggt
     6181 gaactgtgta tttccggcac ggggcttgcc agaggatact acaaacagcc agagctgaca
     6241 gagaaagcat tctccgatca tccgttcctt gaaggggagc gtttataccg aacaggtgat
     6301 gcaggccgct ttttgccgga tggaacgatt gaatatatag gacgttttga tgatcaagtg
     6361 aaaattaggg gttaccgcat tgaactgaaa gaaattgaaa cggttcttcg acaggcgcca
     6421 ggagtgaagg aagcagcagt actggcccgt gatgtttctg ctgaggaaaa agagcttgtt
     6481 gcttatatcg ttctggaaaa gggaaacaat ctcccggatt tgcatcggct tcttgccggg
     6541 acattgcctc cctatatgat tccagcaagt ttcatcaaca tcagccggat gccattaaca
     6601 tccagcggga agcttgaccg ctcagcactt cctgaaccag aaaacaatgc gagcctcaca
     6661 tatatgccgc cccgaacttt aatcgaggct gatctcgcac atatttgggg agatgtgctg
     6721 aataaacagc aaatcggcat tcgtgatgat ttctttcaat taggcggaca gtccttaaaa
     6781 gcggccgcac tggtatcaag aatacataaa aagcttaata tcgagctgcc gatcagtgag
     6841 gttttttcta atccgacagt tgaaagcatg gcagtcaaat tgatgagctt aaaagaacat
     6901 gcttttacac agattgagcc tgcggatcaa agagatgtct atccgctgtc tttctcacaa
     6961 aaacgattat atgctctcca tcagctggca gatgacagca caggctataa catgcccgct
     7021 gtacttgaat tacgcggaaa tctggatcgc cagcggttga gaagcgttct cacagaactt
     7081 gtgaatcggc atgaagcatt gcggactgtt tttgtgcttg acagaggaga gcccgtgcag
     7141 atcattcatc cagagatggc ttttgatctg aaagagcttg aaatggaatc agaacaaatg
     7201 cttgagtccg caatcgaatc ttttatcaaa ccgtttgatc tatcgtccgg tccgcttttt
     7261 agagcatgtg tcattacaat gggcaataat cgcggctttt tgctgctcga tatgcaccat
     7321 attattgccg acggtgtctc gatgagcact cttgtccaag aatttactga cttgtattgc
     7381 gaaaaagagt tgccagcttt aaacctgcat tataaggatt ttgctgtttg gcagcaagaa
     7441 aagtacccga aagagctata caaaaaacag gaggcctact ggctcgatca gcttggcggg
     7501 agtcttccag tattagaatt accgcttgat aaaacaagac cgcgtctccc tgatttcagc
     7561 ggcggaacaa tcgaagtaaa cattgataaa gacacggcag atgagctgca ccgtttaatg
     7621 gttgaaacgg gaacaacgtt gtatatgatt cttctggctg tctattctat tttgctatcc
     7681 aagctaagcg ggcaagagga tattgtcgtc ggctcgcctg ctgccggaag accgcacgcc
     7741 gatctggagc gcgtcatcgg gatgttcgta aatactttag cgatgcgcag ccagcccgag
     7801 ggccacaaaa cgttcagctc gtatttgcag gatattcgcc acctggctct gacggcttac
     7861 gagcatcagg attatccttt tgaggagctg gcagataagc tcgatacaca tcgagaggta
     7921 aatcgcaacc cgctgttcga tgcgatgctc gtgcttcaaa gcagtgagga tttccagttc
     7981 gaagtgcctg gtctatcaat ttcgtctgtc actccaaaac acgatatatc taaattcgat
     8041 ttgacattac acgctgagga gcattcgggc gggattcact gccggtttga atacagcacc
     8101 gctctttttg aagaagagac cattgcgcga tgggcatccc attttattga gctggtgaaa
     8161 ggtgtaacgg ctgataccaa gatgagaatt tcggaaatgc aattgcttcc tgctgcagag
     8221 cgcaatttgc tccttgaaaa aatgggacag tatgccgctt atccgagaaa tgaaaacatt
     8281 gtaagcttat ttgaaaaaaa agccgctgaa catccggagc atctcgcagt ggtgtacggt
     8341 cactctcagc ttacttatcg agacctgaat gaaaaagctg agcggacagc tgctatgctg
     8401 atcaaacaag gggtcagaac tggcgatatc gtaggtctga tgctcgatcg gtcacctgat
     8461 atgatcattg gcattttatc gattttaaaa gctggagggg cctacttgcc gattgatcct
     8521 gaatatcctc aggagcgtat cagttttatg ctcaatgaca gcggggcaga aatgttgctg
     8581 acagagcgcg gccaaaacaa acctgcagac tataacgggc ctattatgta tatcgatgaa
     8641 ggtgatagcg actcaattcc ggatgattta aacattcaag aaaccctatc ggatcagccg
     8701 gcatacgtga tatacacatc cggaacgact ggccagccaa agggcgtcat tgtcgagcac
     8761 cgcaatgtga tcagtctctt aaagcatcaa aacctgcctt ttaaatttgg ccatgaagac
     8821 gtctggacgt tctttcattc atattgcttt gatttctctg tatgggaaat gttcggtgcg
     8881 ttattaaacg gaagtacact agtcgtggtc tctaaagaaa cagcccgtga tccccatgca
     8941 ttccgattat tgttaaaaaa agaacgcgtc actgtactca atcagacccc gacagctttt
     9001 tacggcctga tgcatgaaga tcaaaaccat acggatcgat taaacatccg atacgtgatt
     9061 tttggcggcg aagctttaca gcccggcatg cttcaaagct ggaataaaaa atatcctgat
     9121 actgatctga tcaatatgta tgggattaca gaaacgacgg tacatgtaac attcaaaaaa
     9181 ttgtccgcag cagacattgc aaaaaataaa agcaatatcg gacggccgct ttcaactctg
     9241 caggcttatg tgatggatgc tcatatgaat ctgcagccga tcggagttcc aggggagatg
     9301 tatataggcg gtgaaggtgt ggcacgggga tatctcaaca gagatgagct gaccgctgac
     9361 cgttttgtgc ctaatcctta tcttccgggg gatagattat accgaacagg agatcttgct
     9421 aaacgcctgt caaatggcga gctggaatac ttaggccgca ttgatgatca ggttaaagtc
     9481 agaggacacc gtattgagtt aggcgaaatc caggcggctc ttcttcagct tccagctatt
     9541 aaagaggcgg ctgtcatcac aagaacagat gagcaagggc aagcagctgt atatgcatac
     9601 atcgtgacaa aagatcaaca ggccgcgaat gcatcagaaa tccggacttc tctaaaaacc
     9661 atgctgcctg actttatgct accggcccgt ttgatacaga ttgacagcat cccgctgact
     9721 gttaatggaa aacttgatca gaaagccctg ccggaacctg ataaacacgg ttatattgct
     9781 gatgatatca gaccaagaaa tgagattgaa aaggtgatag ctgaaatttg ggaggagctt
     9841 cttgatgtgg aggagctggg cgtaagcgcc aatttctttg agcttggcgg agattctatt
     9901 aaagcactgc aagtttgtgc cagactgaag cagcgcggct ttgaaacgac agtacgtgag
     9961 atgtttgaac atcagactct tggcgaactg tccgcacgtg ttcgaaaagc cgtacacgtc
    10021 attgaccaag gtccggtcga aggcgagatc acttggacac ctatccagca atggtttttc
    10081 tcgcaatctc tggaaatcaa tcattttaac cagtccgtta tgctctaccg gactgaacga
    10141 tttgacgaga cagcgcttaa aaaggtgcta aaaagcctgg tgactcatca tgacgcacta
    10201 agaatcgtat gccggtatga agatggcagg ccggtacaga taaacagagg gatagatctt
    10261 ccagataagg agctatatgc tcttgaactg tttgatgtaa aggataactt aacagaagcg
    10321 cataacagga ttaaggaagc agccagccag atgcaggagc atttacgttt ggaaactggt
    10381 cccttgcttc acgctggatt gttcaggacc gagaatggtg accatttgtt tctgacgatt
    10441 catcacttag ttgttgatgc ggtttcgtgg cgcattttgt tcgaggattt ttcaacagct
    10501 tacaaacagg cagtctcagg agaaactatt aaactgccgc aaaaaacaga ttcatattta
    10561 acgtattcac aaagtatagc tgactactct aagagccgcc agatgcagcg cgaagcagcg
    10621 tattgggatg agcgagagaa ccgtcacatt caacctattc ctaaagacaa tgaagcagca
    10681 ccaaacacat tcaaagatac agaagtgatt gattttaatc tgtcccgcca tcacacagaa
    10741 ttattgttaa cggctgcaaa taaagcatac agcacggaga tgaatgatat tcttctgaca
    10801 gctttaggcc ttgctttgca gcaatggaca ggctatgacc agtttaaaat cagcatggag
    10861 ggccatggaa gggaatcata tcttgaggat attgacatta gcagaacagt cggctggttc
    10921 acctcgattt atcctgtatg gcttgatatg agccattctg atcataagaa caaagatgag
    10981 cgtctgggcc acctcattaa acagacaaaa gatatgctgc accgtatacc gcataagggc
    11041 gcaggctacg gtgtgctgaa atataccaac aaaaaatggg actctgagaa aggcagcccg
    11101 gacatcagct ttaattattt aggccagttt gatcaggata ttcaatcaaa agcttttgag
    11161 gtttctgaca tcaagccagg gaatgagatc agcccgaact gggagcgtcc tcatgcactg
    11221 gatatcagcg gcgccgtttc ttcgggatgc ctgaacatgc acatgatcta taacaggctt
    11281 caatttgaga aaaaaacaat ccaaacattt gcagagcatt ttaaacagac tctggaaaat
    11341 atcattgagc attgtacggg caaagaaaac cgagaatgga gcgcatctga tttcactgat
    11401 gaagatttaa cacttgatga attgagtgag attatgggtg ccgtcaacaa actataggga
    11461 gaggagattc acactgatgc cgcagcaacc cgaaatacag gatatatacc ctttgtcttt
    11521 tatgcaggaa gggatgcttt ttcattcact gtatgatgaa cagtcaagag cttattttga
    11581 acaggcttct tttacgatcc atggacagct tgacttggag cgtttccaga aaagtatgga
    11641 tgctgttttt gaaagatacg aaatcttccg aacggcgttc atctataaaa atgtagccaa
    11701 accacgtcaa gtcgtgctca agcatcgtca ttgccatgtt cattttgaag atatttctca
    11761 tctcaacgaa agagataaag aacattgtac cgaggcattc aaagagcagg ataaatccag
    11821 gggattcgat ctccaaacag atgtactgat gagaatatct attttaaaat gggcgcctaa
    11881 tcgttatgtc tgtatctgga gccatcatca tattttaatg gatggctggt gtttaggcat
    11941 cgtcattaaa gattttcttc acatttatca agcgctgggt aaaggtcagc ttccggattt
    12001 gcatcccgtt cagtcgtacg ggacgtatat taaatggctg atgcagcaag accgagaaga
    12061 agcagctgag tattggaaaa agaggcttca gcatttcgaa aaagctacgc ctctgccgaa
    12121 aagaacagat caaataccgg atgggacatt agagcagatc acgttcacca tttctgaaaa
    12181 agaaacctcc gaattacaga aaatcgcagc agcttctgga gcgacactaa acactgtttt
    12241 ccaagcttta tggggaatca tgctccaaaa gttcaatcgc tgcggcgatg ctgtgttcgg
    12301 atccgttata tcaggcagaa cttctgagct aagagatgtg gaaaacatgg tcggactttt
    12361 tatcaatacc attcctattc gagtccaaag tgattctctt tctttttctg acctagtcag
    12421 caggatgcaa agggacatga ctgaagcaga agcatatagt tacttccctt tatatgacat
    12481 tcaggcgcag agtgctctca aacaagagct tatcgatcat attatcgtct ttgaaaatac
    12541 acctacccag caagagattg aagggctgaa tcaggctgga tcatttgatt tctccgtgaa
    12601 ggattttgat atggaagagg tgaccaatta tagctgcagt gtcaaagtga tcccaggccg
    12661 tacgttgtac gttcggattc attttcatac cggcgcctat caaccaagca tgatgtccga
    12721 gataaaagat tatttacagc acatggtctc tgacgtcatc tctgatccat ctcttcccgt
    12781 gtcaaagatg acattgctag atgagaacaa aacacggaaa atcgtttctc aaaacaacgg
    12841 ggcagtatct gtttcgcctg aagccccaac cctgcacgga ctgtttgaac gacaggcggc
    12901 tttcacaccg gagcggccag ccatccgctt ttccagcggt tcgctgacgt acgctgagct
    12961 tgacatgtat gccagccggc tggccgcgcg cctcgcggca cgcggcgtca cgaaggaaag
    13021 catcgtcggt gtcctgtctg aacggtcacc tgaaatgctg atagctgtac ttgctgtatt
    13081 gaaggcaggc ggggcgtatt tgccgcttga tcctgcatat ccaaaggagc ggctgagcta
    13141 catgctgaaa gacagcgggg ccgcgctctt gctggcacag ccgggatgtt ccgcaccggg
    13201 cttttccgga gagatgcttg aagtggacat ggcatctctt gcgagcgaaa aagcagaaaa
    13261 cgatgtgttt actcctgctg acggctgttc tctcgcctat gtcatctata catcgggctc
    13321 caccgggaag ccaaaaggag tggccgtcga gcaccgccag gctgtttcct ttctgactgg
    13381 catgcagcgt cagtttccgc ttcaggaaga tgacattgtt atggtgaaaa cctctttttc
    13441 ctttgatgcg tctgtgtggc agctgttttg gtggtccctt tctggcgctt cggcttacct
    13501 gcttccgccc ggctgggaga aagacccggc attgattgta aaagccattc atcaggaaaa
    13561 agtgacaacg gctcatttta ttccggctat gctgaacagc tttctggatc aagcggaaat
    13621 gaaagcgctc ggtgatggga caagcctgaa gcgtgtattc gccggaggtg aaccgcttgc
    13681 gccccatgtg gcagcccgtt ttgcttcttt attgccgcag gtatcgctga ttcatggcta
    13741 cgggccgaca gaagcgacgg ttgacgcggc attttacgtg ttggacccag ggcgggacag
    13801 ggatcgcttg cggattccga tcgggaagcc cgtacccggt gcgcgtttgt atgttttaga
    13861 tgcgcattta gccgtacagc cttgcggtgt cgccggcgaa ctgtacatag ccggagcggg
    13921 tgtggccaga ggctatttga atcggccggc cttaacggag gagcgttttc tcgaggaccc
    13981 gttttacccg ggggaacgaa tgtataaaac tggggatttg gcgcgctggc tccctgaagg
    14041 acacgttgag ttccttggcc ggttagatga tcaggtgaaa atccgcggct accggattga
    14101 gcccggagaa attgaagcag tgctaagagg catagagggc atcagagagg cagccgttac
    14161 cgtacggaca gacagcggcg agccggaatt atgcgcctat acagaaggac taagaagaaa
    14221 cgaagtgcgg acgcagcttg aaagactgct gccgagctac atgatcccag ctcatatgat
    14281 agagatggaa cggtggccgg ttacgccaag cggaaagctg gaccgaaacg ccctgccagc
    14341 tcctggcgga gcggcagatg aggaggccta cacggcgccg agaaatgtga cagagatgaa
    14401 gcttgcccag ctgtgggagg acgtgctgaa aaacggccct gtcgggattc acgacaactt
    14461 ttttgatcgc ggaggacatt ccttaaaagc aaccgcactt gtgtcccgga tcgccaaaga
    14521 attcgatgta caggtgccgc tgaaagatgt gtttgcccat ccgactgttg aagggctggc
    14581 ttccgttatc cgtgaaggaa cggacagtcc atatgaagcg atgaaactgg ctgaaaagcg
    14641 cgaggcctat ccggtttcct ccgcccaaaa aaggatctat gtccttcagc agctggagga
    14701 cggagggata ggctacaata tgccggctat gttagagctg gaagggaagc t
//
