LOCUS       NZ_JALAWW010000017      9401 bp    DNA     linear   CON 26-JAN-2024
DEFINITION  Bacillus inaquosorum strain T5B6 contig_0000017, whole genome
            shotgun sequence.
ACCESSION   NZ_JALAWW010000017
VERSION     NZ_JALAWW010000017.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus inaquosorum
  ORGANISM  Bacillus inaquosorum
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 9401)
  AUTHORS   Dunlap,C.
  TITLE     Crop Bioprotection Bacillus Genome Sequencing
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9401)
  AUTHORS   Dunlap,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-FEB-2022) CBP, USDA-ARS-NCAUR, 1815 N. University St.,
            Peoria, IL 61604, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC NGS Cell v. 21
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 332.12328936298655x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/24/2024 03:03:42
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,623
            CDSs (total)                      :: 4,534
            Genes (coding)                    :: 4,405
            CDSs (with protein)               :: 4,405
            Genes (RNA)                       :: 89
            rRNAs                             :: 3, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 78
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 82 of 129
            Pseudo Genes (incomplete)         :: 79 of 129
            Pseudo Genes (internal stop)      :: 22 of 129
            Pseudo Genes (multiple problems)  :: 45 of 129
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 15:01:03
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 9401
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JALAWW010000017.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     protocluster    1..9401
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<0:>9399](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(<1..>9399)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     gene            complement(<1..5653)
                     /locus_tag="MOF23_RS22865"
                     /old_locus_tag="MOF23_22810"
     CDS             complement(<1..5653)
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (0-30). E-value: 1.7e-17.
                     Score: 54.3. Matches aSDomain:
                     nrpspksdomains_MOF23_RS22865_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (7-304). E-value:
                     1.9e-116. Score: 380.3. Matches aSDomain:
                     nrpspksdomains_MOF23_RS22865_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (468-865). E-value:
                     1.8e-103. Score: 338.2. Matches aSDomain:
                     nrpspksdomains_MOF23_RS22865_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (971-1040). E-value: 1.1e-23. Score:
                     75.2. Matches aSDomain: nrpspksdomains_MOF23_RS22865_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1054-1333). E-value:
                     1.4e-103. Score: 338.0. Matches aSDomain:
                     nrpspksdomains_MOF23_RS22865_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1499-1884). E-value:
                     6.9e-101. Score: 329.7. Matches aSDomain:
                     nrpspksdomains_MOF23_RS22865_AMP-binding.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389713.2"
                     /locus_tag="MOF23_RS22865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOF23_22810"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_268411604.1"
                     /sec_met_domain="AMP-binding (E-value: 6.5e-111, bitscore:
                     357.8, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.3e-17, bitscore:
                     49.7, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 5.2e-89, bitscore:
                     285.3, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKANSIQDIYALSYMQEGMLFHSLLQKDSQAYVEQASFTIEGKV
                     NSQFFQNSINALVARHDIFRTIFISQNVSSPQQVVLRERNIIVQEKDITHLNEEKQAQF
                     IEQLKEKDRAQGFHLQKDMLMRIALIQTGESQYTCIWTFHHIMMDGWCLSIVLKEFLHI
                     YASYVNATPISLESVQPYGSYIKWLMEQDKEQAVSYWEHYLSGHGQQTMLPKQKKTKGR
                     SRQEHVTFSFSKEESSRLSELAAREEVTLSTIFHTIWGILLQKYNNNDDAVFGSVISGR
                     PAEIEGIEHMVGLFINTIPIRVQGAKTPFIQLIKDMQKDRLAAEAYSYHPLYEIQARSA
                     VKQGLIDHILVFENYPVQQEIQMLNKQEHASDLFQIHNFTVADETNYSFYLMVAPGEEI
                     HIKMSYDAEQHDRSFVLSVKEHLLNAVSQILNNPNLPPEEIEITTDTEKRQLIGEIADR
                     TPVYETIHAMFEKQAEKTPDAHAVIDQACTLTYKELNKSANRLARHLRMKGVARQEPVA
                     IMMERSAALITGVLGILKAGGAIVPIDPHYPADRIRYILNDCGCSHVVSQAHLSASLDN
                     NYLITHAEDIESTEDGSNIKSVNNADDLLYLIYTSGTTGKPKGVQFEHRNMANLLKFEF
                     AHSGIDFEADVLQFATPAFDVCYQEIFSALLKGGTLHIVPEAIKRDVPQLFAFINKHQT
                     NIVFLPTAFIKMIFSERQLANSFPYGVKHLITAGEQLIISDIFQDVLRERGIHLHNHYG
                     PSETHVVSTYTIHPGDPIPEFPPIGKPIGCTDLYILNHQKQLQPCGVPGELYISGASVA
                     RGYVNHDKLTRDKFSSDPFRPGAIMYRTGDLARRLGDGNIEYIGRADKQVKIRGYRIEP
                     QEIEVTLMNHRDIKEAAILIRQDQNGEHELCAYYCSVQKLNAIDLRSYMASELPEYMIP
                     AKWIWVDSIPLTPNGKVDQAALPAPDASISGNPYAAPRNLIEAKLSQIFEDVLKNGHIG
                     IQDNFFDHGGHSLKATVLMSRIAKEFHVQVPLKDIFAHPTVEGLALIIQDAEENPYAAI
                     EPAEERKTYPVSSAQKRIYVLQQLDEGVAYNMPAVLELEGALDVAKLSAVCKELISRHE
                     PLRTSFVSEADGEPVQSIHTEVPFTLSIETAIEGFIRPFDLSQAPLFRAGLIKVTNEKH
                     VLLVDMHHIISDGVSVQLLIREFTDLYANRQLKPLRIQYKDYAVWQQQFKKGDSYQKQE
                     TYWLQQFSGDLPALELPTDKRRPAERHFTGGKVTFQLDKEITARIKRLANKNRSTLYMT
                     LLALYSAFLSRLSGQDDIVIGSPIAGRPHADLEAVLGMFVNTLALRTRPAGNMTFEEFL
                     KEVRQTALEAYEHQDYPFEELVDKLGVQREMSRNPLFDTTLVLQNMEQQKLKMKDVQLR
                     WNDLQHPISKFDISLYVTEHDSELFCQFEYSTALFEKETIQRWAGLFTTLVEHTAVSPK
                     TELDDIPLLTKEEERAFIESCHPFQETGYPMNQTLHYALEQQAAKTPDQPAVIFEHGAM
                     TYKELNEQANRIAWELIGRGVKSETTVAIIGKRSPEMLIGIYGILKAGGAYLPIDPDYP
                     EERISFLLEDSGTDILLLQSSSLHVPAFAGEIVYLNQANSGLKHRLSNPNVDVLPKSLA
                     YVIYTSGSTGRPKGVEVEHRSAVNFLNSLQSRYRLKQSDVIMHKTSYSFDASIWELFWW
                     PYAGASVYLLPQGGEKEPEVIAKAVEEQEITAMHFVPSMLHAFLEHIKYRPVPIKINGL
                     KRVFSGGEQLGTHLVSRFCELLPGVALTNSYGPTEATVEAAFFDCPLHEKLERVPIGKS
                     VHHVRLYILNQKQRMLPAGCIGELYIAGAGVARGYLNRPALTEERFLEDPFYPGERMYK
                     TGDLARWLPD"
     source          1..9401
                     /db_xref="taxon:483913"
                     /mol_type="genomic DNA"
                     /organism="Bacillus inaquosorum"
                     /strain="T5B6"
                     /submitter_seqid="contig_0000017"
     region          1..9401
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..9401
                     /SMILES="NC([*])C(=O)N1C(CCC1)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     aSDomain        complement(2..1156)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOF23_RS22865_AMP-binding.2"
                     /evalue="6.90E-101"
                     /label="MOF23_RS22865_AMP-binding.2"
                     /locus_tag="MOF23_RS22865"
                     /protein_end="1884"
                     /protein_start="1499"
                     /score="329.7"
                     /specificity="substrate consensus: Glu"
                     /tool="antismash"
                     /translation="LEQQAAKTPDQPAVIFEHGAMTYKELNEQANRIAWELIGRGVKSE
                     TTVAIIGKRSPEMLIGIYGILKAGGAYLPIDPDYPEERISFLLEDSGTDILLLQSSSLH
                     VPAFAGEIVYLNQANSGLKHRLSNPNVDVLPKSLAYVIYTSGSTGRPKGVEVEHRSAVN
                     FLNSLQSRYRLKQSDVIMHKTSYSFDASIWELFWWPYAGASVYLLPQGGEKEPEVIAKA
                     VEEQEITAMHFVPSMLHAFLEHIKYRPVPIKINGLKRVFSGGEQLGTHLVSRFCELLPG
                     VALTNSYGPTEATVEAAFFDCPLHEKLERVPIGKSVHHVRLYILNQKQRMLPAGCIGEL
                     YIAGAGVARGYLNRPALTEERFLEDPFYPGERMYKTGDLARWLPD"
     aSModule        complement(2..2491)
                     /domains="nrpspksdomains_MOF23_RS22865_Condensation_LCL.1"
                     /domains="nrpspksdomains_MOF23_RS22865_AMP-binding.2"
                     /incomplete
                     /locus_tags="MOF23_RS22865"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(71..160)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF23_RS22865_0020"
                     /evalue="5.30E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="MOF23_RS22865"
                     /protein_end="1861"
                     /protein_start="1831"
                     /score="57.1"
                     /tool="antismash"
                     /translation="PAGCIGELYIAGAGVARGYLNRPALTEERF"
     CDS_motif       complement(269..298)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF23_RS22865_0019"
                     /evalue="4.00E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="MOF23_RS22865"
                     /protein_end="1795"
                     /protein_start="1785"
                     /score="7.1"
                     /tool="antismash"
                     /translation="SYGPTEATVE"
     CDS_motif       complement(683..742)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF23_RS22865_0018"
                     /evalue="2.70E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="MOF23_RS22865"
                     /protein_end="1657"
                     /protein_start="1637"
                     /score="32.1"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGRPKGVEVEH"
     CDS_motif       complement(929..967)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF23_RS22865_0017"
                     /evalue="7.90E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="MOF23_RS22865"
                     /protein_end="1575"
                     /protein_start="1562"
                     /score="15.9"
                     /tool="antismash"
                     /translation="GILKAGGAYLPID"
     CDS_motif       complement(1496..1615)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF23_RS22865_0016"
                     /evalue="6.20E-21"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="MOF23_RS22865"
                     /protein_end="1386"
                     /protein_start="1346"
                     /score="66.8"
                     /tool="antismash"
                     /translation="RQTALEAYEHQDYPFEELVDKLGVQREMSRNPLFDTTLVL"
     aSDomain        complement(1655..2491)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOF23_RS22865_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.40E-103"
                     /label="MOF23_RS22865_Condensation_LCL.1"
                     /locus_tag="MOF23_RS22865"
                     /protein_end="1333"
                     /protein_start="1054"
                     /score="338.0"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIISDG"
                     /tool="antismash"
                     /translation="KTYPVSSAQKRIYVLQQLDEGVAYNMPAVLELEGALDVAKLSAVC
                     KELISRHEPLRTSFVSEADGEPVQSIHTEVPFTLSIETAIEGFIRPFDLSQAPLFRAGL
                     IKVTNEKHVLLVDMHHIISDGVSVQLLIREFTDLYANRQLKPLRIQYKDYAVWQQQFKK
                     GDSYQKQETYWLQQFSGDLPALELPTDKRRPAERHFTGGKVTFQLDKEITARIKRLANK
                     NRSTLYMTLLALYSAFLSRLSGQDDIVIGSPIAGRPHADLEAVLGMFVNTLALRTRP"
     CDS_motif       complement(1664..1753)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF23_RS22865_0015"
                     /evalue="2.50E-16"
                     /label="C5_LCL_267-296"
                     /locus_tag="MOF23_RS22865"
                     /protein_end="1330"
                     /protein_start="1300"
                     /score="52.0"
                     /tool="antismash"
                     /translation="DIVIGSPIAGRPHADLEAVLGMFVNTLALR"
     CDS_motif       complement(2012..2044)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF23_RS22865_0014"
                     /evalue="9.40E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="MOF23_RS22865"
                     /protein_end="1214"
                     /protein_start="1203"
                     /score="12.0"
                     /tool="antismash"
                     /translation="QYKDYAVWQQQ"
     CDS_motif       complement(2075..2140)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF23_RS22865_0013"
                     /evalue="1.70E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="MOF23_RS22865"
                     /protein_end="1193"
                     /protein_start="1171"
                     /score="30.2"
                     /tool="antismash"
                     /translation="MHHIISDGVSVQLLIREFTDLY"
     CDS_motif       complement(2312..2425)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF23_RS22865_0012"
                     /evalue="6.60E-15"
                     /label="C2_LCL_024-062"
                     /locus_tag="MOF23_RS22865"
                     /protein_end="1114"
                     /protein_start="1076"
                     /score="47.5"
                     /tool="antismash"
                     /translation="AYNMPAVLELEGALDVAKLSAVCKELISRHEPLRTSFV"
     aSDomain        complement(2534..2740)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOF23_RS22865_PCP.1"
                     /evalue="1.10E-23"
                     /label="MOF23_RS22865_PCP.1"
                     /locus_tag="MOF23_RS22865"
                     /protein_end="1040"
                     /protein_start="971"
                     /score="75.2"
                     /tool="antismash"
                     /translation="EAKLSQIFEDVLKNGHIGIQDNFFDHGGHSLKATVLMSRIAKEFH
                     VQVPLKDIFAHPTVEGLALIIQDA"
     aSModule        complement(2534..5632)
                     /complete
                     /domains="nrpspksdomains_MOF23_RS22865_Condensation_DCL.1"
                     /domains="nrpspksdomains_MOF23_RS22865_AMP-binding.1"
                     /domains="nrpspksdomains_MOF23_RS22865_PCP.1"
                     /locus_tags="MOF23_RS22865"
                     /monomer_pairings="Pro -> Pro"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(3029..3094)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF23_RS22865_0011"
                     /evalue="1.60E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="MOF23_RS22865"
                     /protein_end="875"
                     /protein_start="853"
                     /score="36.1"
                     /tool="antismash"
                     /translation="YIGRADKQVKIRGYRIEPQEIE"
     aSDomain        complement(3059..4249)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOF23_RS22865_AMP-binding.1"
                     /evalue="1.80E-103"
                     /label="MOF23_RS22865_AMP-binding.1"
                     /locus_tag="MOF23_RS22865"
                     /protein_end="865"
                     /protein_start="468"
                     /score="338.2"
                     /specificity="substrate consensus: Pro"
                     /tool="antismash"
                     /translation="FEKQAEKTPDAHAVIDQACTLTYKELNKSANRLARHLRMKGVARQ
                     EPVAIMMERSAALITGVLGILKAGGAIVPIDPHYPADRIRYILNDCGCSHVVSQAHLSA
                     SLDNNYLITHAEDIESTEDGSNIKSVNNADDLLYLIYTSGTTGKPKGVQFEHRNMANLL
                     KFEFAHSGIDFEADVLQFATPAFDVCYQEIFSALLKGGTLHIVPEAIKRDVPQLFAFIN
                     KHQTNIVFLPTAFIKMIFSERQLANSFPYGVKHLITAGEQLIISDIFQDVLRERGIHLH
                     NHYGPSETHVVSTYTIHPGDPIPEFPPIGKPIGCTDLYILNHQKQLQPCGVPGELYISG
                     ASVARGYVNHDKLTRDKFSSDPFRPGAIMYRTGDLARRLGDGNIEYIGRADKQVKIR"
     CDS_motif       complement(3176..3265)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF23_RS22865_0010"
                     /evalue="5.10E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="MOF23_RS22865"
                     /protein_end="826"
                     /protein_start="796"
                     /score="41.2"
                     /tool="antismash"
                     /translation="PCGVPGELYISGASVARGYVNHDKLTRDKF"
     CDS_motif       complement(3374..3400)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF23_RS22865_0009"
                     /evalue="4.20E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="MOF23_RS22865"
                     /protein_end="760"
                     /protein_start="751"
                     /score="4.2"
                     /tool="antismash"
                     /translation="YGPSETHVV"
     CDS_motif       complement(3782..3838)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF23_RS22865_0008"
                     /evalue="1.10E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="MOF23_RS22865"
                     /protein_end="624"
                     /protein_start="605"
                     /score="27.3"
                     /tool="antismash"
                     /translation="YLIYTSGTTGKPKGVQFEH"
     CDS_motif       complement(4022..4063)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF23_RS22865_0007"
                     /evalue="2.80E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="MOF23_RS22865"
                     /protein_end="544"
                     /protein_start="530"
                     /score="14.3"
                     /tool="antismash"
                     /translation="LGILKAGGAIVPID"
     CDS_motif       complement(4586..4702)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF23_RS22865_0006"
                     /evalue="1.10E-20"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="MOF23_RS22865"
                     /protein_end="356"
                     /protein_start="317"
                     /score="66.2"
                     /tool="antismash"
                     /translation="QKDRLAAEAYSYHPLYEIQARSAVKQGLIDHILVFENYP"
     aSDomain        complement(4742..5632)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOF23_RS22865_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="1.90E-116"
                     /label="MOF23_RS22865_Condensation_DCL.1"
                     /locus_tag="MOF23_RS22865"
                     /protein_end="304"
                     /protein_start="7"
                     /score="380.3"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIMMDG"
                     /tool="antismash"
                     /translation="QDIYALSYMQEGMLFHSLLQKDSQAYVEQASFTIEGKVNSQFFQN
                     SINALVARHDIFRTIFISQNVSSPQQVVLRERNIIVQEKDITHLNEEKQAQFIEQLKEK
                     DRAQGFHLQKDMLMRIALIQTGESQYTCIWTFHHIMMDGWCLSIVLKEFLHIYASYVNA
                     TPISLESVQPYGSYIKWLMEQDKEQAVSYWEHYLSGHGQQTMLPKQKKTKGRSRQEHVT
                     FSFSKEESSRLSELAAREEVTLSTIFHTIWGILLQKYNNNDDAVFGSVISGRPAEIEGI
                     EHMVGLFINTIPIRVQ"
     CDS_motif       complement(4748..4843)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF23_RS22865_0005"
                     /evalue="8.30E-20"
                     /label="C5_DCL_263-294"
                     /locus_tag="MOF23_RS22865"
                     /protein_end="302"
                     /protein_start="270"
                     /score="63.2"
                     /tool="antismash"
                     /translation="DAVFGSVISGRPAEIEGIEHMVGLFINTIPIR"
     CDS_motif       complement(5078..5116)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF23_RS22865_0004"
                     /evalue="2.10E-02"
                     /label="C4_DCL_171-183"
                     /locus_tag="MOF23_RS22865"
                     /protein_end="192"
                     /protein_start="179"
                     /score="8.0"
                     /tool="antismash"
                     /translation="PYGSYIKWLMEQD"
     CDS_motif       complement(5162..5227)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF23_RS22865_0003"
                     /evalue="4.90E-11"
                     /label="C3_DCL_135-156"
                     /locus_tag="MOF23_RS22865"
                     /protein_end="164"
                     /protein_start="142"
                     /score="35.0"
                     /tool="antismash"
                     /translation="FHHIMMDGWCLSIVLKEFLHIY"
     CDS_motif       complement(5447..5560)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF23_RS22865_0002"
                     /evalue="1.10E-14"
                     /label="C2_DCL_024-062"
                     /locus_tag="MOF23_RS22865"
                     /protein_end="69"
                     /protein_start="31"
                     /score="46.6"
                     /tool="antismash"
                     /translation="AYVEQASFTIEGKVNSQFFQNSINALVARHDIFRTIFI"
     aSDomain        complement(5564..5653)
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOF23_RS22865_NRPS-COM_Nterm.1"
                     /evalue="1.70E-17"
                     /label="MOF23_RS22865_NRPS-COM_Nterm.1"
                     /locus_tag="MOF23_RS22865"
                     /protein_end="30"
                     /protein_start="0"
                     /score="54.3"
                     /tool="antismash"
                     /translation="MTKANSIQDIYALSYMQEGMLFHSLLQKDS"
     CDS_motif       complement(5582..5623)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF23_RS22865_0001"
                     /evalue="2.30E-04"
                     /label="C1_DCL_004-017"
                     /locus_tag="MOF23_RS22865"
                     /protein_end="24"
                     /protein_start="10"
                     /score="13.3"
                     /tool="antismash"
                     /translation="YALSYMQEGMLFHS"
     CDS             complement(5678..>9399)
                     /NRPS_PKS="Domain: AMP-binding (195-588). E-value:
                     2.6e-114. Score: 374.0. Matches aSDomain:
                     nrpspksdomains_MOF23_RS22870_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (693-761). E-value: 1.1e-24. Score:
                     78.4. Matches aSDomain: nrpspksdomains_MOF23_RS22870_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (771-1073). E-value:
                     7.6e-166. Score: 545.0. Matches aSDomain:
                     nrpspksdomains_MOF23_RS22870_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (1079-1233). E-value: 1.2e-52.
                     Score: 169.8. Matches aSDomain:
                     nrpspksdomains_MOF23_RS22870_TIGR01720.1"
                     /codon_start=2
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389714.1"
                     /locus_tag="MOF23_RS22870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOF23_22815"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_268411605.1"
                     /sec_met_domain="AMP-binding (E-value: 4.7e-122, bitscore:
                     394.5, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.2e-16, bitscore:
                     48.2, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 5.1e-79, bitscore:
                     252.5, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="SPIAGRPHKDLEPILGMFVNTLALRTRPEGGKPFVEYLQEVRETA
                     LEAYEHQDYPFEELVDKLKLTRDMSRNPLFDVMFVLQNMDQESIQLEELHLKPAANNGH
                     QTSKFDLTLYAHEQPCGLLTFQMEFSTDLYKKKTIEKWLQYFINMLLSITQDNKAALGT
                     INILNEDETHYLIHELNHTKIDYPRNETISRLFEMQAEQTPNAIAIVSDTQELTYADLN
                     SRANQIASVLQRKGVGPDRVVALLTGRTPELIAGMLGILKAGGAYLPIASDLPVERIAY
                     MLSDSGAALLLQSEKTEKQLLDIECEQIIIENIQKQGETKNFESSAGAHSLAYIIYTSG
                     STGKPKGVMIEQRSVIRLVKNSNYITFTPADRLLMTSSIGFDVVTFEIFGPLLNGAALH
                     LSDKQVFLDSYQLQRYIELHGITTMWLTSSLFNHLTEQNETTFSQLNHLIIGGEALSAS
                     HVNRIRNVCPEVSIWNGYGPTENTTFSTCFHIQKTYELSIPIGRPVGNSTAYILNKWGM
                     LQPVGTVGELCVGGDGVARGYLGRPDLTKEKFVPNPFAPGDRLYRTGDLARWLPDGTIE
                     YVGRIDDQVKVRGYRVELGEIESALRQIDGVKEAAVLARTGQTGSKELFGYISVNAGTN
                     AEQVRSLLARSLPNYMIPAYIIEMETLPLTSNGKLNRKALPEPDFASKQTYVPPRDDLE
                     EQLALIWQEVLGIQRIGIEDSFFELGGDSIKALQVSARLGRHGLSLQVSDLFRHPKIKD
                     LSPFIRKTERIIEQGPIQGDVPWTPVQQWFLSQDIEERHHFNQSVMLFHSDRLSEDALR
                     AALKKLAEHHDALRMVYRNDDGRWIQINQGIQESQLYSLRISDLLQSESGWETQIKQEV
                     ADLQQSINLQEGPLLHAAWFKTLTGDYLFLAIHHLVVDGVAWRILLEDLSAGYQQASSG
                     QAIQLPPKTDSYQEYARRIQEYAQSSRLIREEAYWRTVEEQQAAELPYEMPLHENTDFS
                     RRDSIRFSLSEADTAVLLQNVNHAYGTDTQDILLTAASLAICEWTGGSKLRIAMEGHGR
                     EHILPELDISRTVGWFTSMYPALISFENHRDELGTAVKTVKDTLGRIPNKGVGYGILKY
                     LTHPENKSIAFSKTPDISFNYLGQFNDIERQDSFRPSSLGSGKDITHTWKREQIIEMSA
                     MAADKKLHFNLSYPPARFHRNTMKQLINRIEHFLRDIMKHCAGKQKAEKTLSDFSSQSL
                     TAEDLDSISSLVEEL"
     gene            complement(5678..>9401)
                     /locus_tag="MOF23_RS22870"
                     /old_locus_tag="MOF23_22815"
     aSDomain        complement(5699..6160)
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOF23_RS22870_TIGR01720.1"
                     /evalue="1.20E-52"
                     /label="MOF23_RS22870_TIGR01720.1"
                     /locus_tag="MOF23_RS22870"
                     /protein_end="1233"
                     /protein_start="1079"
                     /score="169.8"
                     /tool="antismash"
                     /translation="ELGTAVKTVKDTLGRIPNKGVGYGILKYLTHPENKSIAFSKTPDI
                     SFNYLGQFNDIERQDSFRPSSLGSGKDITHTWKREQIIEMSAMAADKKLHFNLSYPPAR
                     FHRNTMKQLINRIEHFLRDIMKHCAGKQKAEKTLSDFSSQSLTAEDLDSI"
     aSModule        complement(5699..8812)
                     /complete
                     /domains="nrpspksdomains_MOF23_RS22870_AMP-binding.1"
                     /domains="nrpspksdomains_MOF23_RS22870_PCP.1"
                     /domains="nrpspksdomains_MOF23_RS22870_Epimerization.1"
                     /domains="nrpspksdomains_MOF23_RS22870_TIGR01720.1"
                     /locus_tags="MOF23_RS22870"
                     /monomer_pairings="X -> D-X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(6074..6136)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF23_RS22870_0010"
                     /evalue="7.50E-10"
                     /label="NRPS-E6"
                     /locus_tag="MOF23_RS22870"
                     /protein_end="1108"
                     /protein_start="1087"
                     /score="31.0"
                     /tool="antismash"
                     /translation="VKDTLGRIPNKGVGYGILKYL"
     aSDomain        complement(6179..7084)
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOF23_RS22870_Epimerization.1"
                     /evalue="7.60E-166"
                     /label="MOF23_RS22870_Epimerization.1"
                     /locus_tag="MOF23_RS22870"
                     /protein_end="1073"
                     /protein_start="771"
                     /score="545.0"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLVVDG"
                     /tool="antismash"
                     /translation="GDVPWTPVQQWFLSQDIEERHHFNQSVMLFHSDRLSEDALRAALK
                     KLAEHHDALRMVYRNDDGRWIQINQGIQESQLYSLRISDLLQSESGWETQIKQEVADLQ
                     QSINLQEGPLLHAAWFKTLTGDYLFLAIHHLVVDGVAWRILLEDLSAGYQQASSGQAIQ
                     LPPKTDSYQEYARRIQEYAQSSRLIREEAYWRTVEEQQAAELPYEMPLHENTDFSRRDS
                     IRFSLSEADTAVLLQNVNHAYGTDTQDILLTAASLAICEWTGGSKLRIAMEGHGREHIL
                     PELDISRTVGWFTSMYPALIS"
     CDS_motif       complement(6185..6232)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF23_RS22870_0009"
                     /evalue="5.90E-09"
                     /label="NRPS-E5"
                     /locus_tag="MOF23_RS22870"
                     /protein_end="1071"
                     /protein_start="1055"
                     /score="27.9"
                     /tool="antismash"
                     /translation="DISRTVGWFTSMYPAL"
     CDS_motif       complement(6638..6703)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF23_RS22870_0008"
                     /evalue="3.20E-11"
                     /label="NRPS-E2"
                     /locus_tag="MOF23_RS22870"
                     /protein_end="920"
                     /protein_start="898"
                     /score="35.4"
                     /tool="antismash"
                     /translation="LFLAIHHLVVDGVAWRILLEDL"
     CDS_motif       complement(6908..6985)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF23_RS22870_0007"
                     /evalue="1.70E-05"
                     /label="C2_LCL_024-062"
                     /locus_tag="MOF23_RS22870"
                     /protein_end="830"
                     /protein_start="804"
                     /score="17.2"
                     /tool="antismash"
                     /translation="RLSEDALRAALKKLAEHHDALRMVYR"
     aSDomain        complement(7115..7318)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOF23_RS22870_PCP.1"
                     /evalue="1.10E-24"
                     /label="MOF23_RS22870_PCP.1"
                     /locus_tag="MOF23_RS22870"
                     /protein_end="761"
                     /protein_start="693"
                     /score="78.4"
                     /tool="antismash"
                     /translation="EEQLALIWQEVLGIQRIGIEDSFFELGGDSIKALQVSARLGRHGL
                     SLQVSDLFRHPKIKDLSPFIRKT"
     CDS_motif       complement(7604..7669)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF23_RS22870_0006"
                     /evalue="1.80E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="MOF23_RS22870"
                     /protein_end="598"
                     /protein_start="576"
                     /score="39.0"
                     /tool="antismash"
                     /translation="YVGRIDDQVKVRGYRVELGEIE"
     aSDomain        complement(7634..8812)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOF23_RS22870_AMP-binding.1"
                     /evalue="2.60E-114"
                     /label="MOF23_RS22870_AMP-binding.1"
                     /locus_tag="MOF23_RS22870"
                     /protein_end="588"
                     /protein_start="195"
                     /score="374.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FEMQAEQTPNAIAIVSDTQELTYADLNSRANQIASVLQRKGVGPD
                     RVVALLTGRTPELIAGMLGILKAGGAYLPIASDLPVERIAYMLSDSGAALLLQSEKTEK
                     QLLDIECEQIIIENIQKQGETKNFESSAGAHSLAYIIYTSGSTGKPKGVMIEQRSVIRL
                     VKNSNYITFTPADRLLMTSSIGFDVVTFEIFGPLLNGAALHLSDKQVFLDSYQLQRYIE
                     LHGITTMWLTSSLFNHLTEQNETTFSQLNHLIIGGEALSASHVNRIRNVCPEVSIWNGY
                     GPTENTTFSTCFHIQKTYELSIPIGRPVGNSTAYILNKWGMLQPVGTVGELCVGGDGVA
                     RGYLGRPDLTKEKFVPNPFAPGDRLYRTGDLARWLPDGTIEYVGRIDDQVKVR"
     CDS_motif       complement(7751..7840)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF23_RS22870_0005"
                     /evalue="8.20E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="MOF23_RS22870"
                     /protein_end="549"
                     /protein_start="519"
                     /score="56.4"
                     /tool="antismash"
                     /translation="PVGTVGELCVGGDGVARGYLGRPDLTKEKF"
     CDS_motif       complement(8345..8401)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF23_RS22870_0004"
                     /evalue="1.10E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="MOF23_RS22870"
                     /protein_end="351"
                     /protein_start="332"
                     /score="33.3"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGKPKGVMIE"
     CDS_motif       complement(8588..8626)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF23_RS22870_0003"
                     /evalue="1.70E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="MOF23_RS22870"
                     /protein_end="270"
                     /protein_start="257"
                     /score="15.0"
                     /tool="antismash"
                     /translation="LGILKAGGAYLPI"
     CDS_motif       complement(9155..9274)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF23_RS22870_0002"
                     /evalue="9.40E-24"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="MOF23_RS22870"
                     /protein_end="81"
                     /protein_start="41"
                     /score="75.9"
                     /tool="antismash"
                     /translation="RETALEAYEHQDYPFEELVDKLKLTRDMSRNPLFDVMFVL"
     CDS_motif       complement(9323..9397)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOF23_RS22870_0001"
                     /evalue="1.50E-11"
                     /label="C5_LCL_267-296"
                     /locus_tag="MOF23_RS22870"
                     /protein_end="25"
                     /protein_start="0"
                     /score="36.6"
                     /tool="antismash"
                     /translation="SPIAGRPHKDLEPILGMFVNTLALR"
ORIGIN
        1 cgtcaggaag ccagcgcgcc aaatccccgg ttttgtacat gcgttcaccc gggtaaaacg
       61 ggtcctcaag aaaacgctcc tccgttaagg ccggccgatt caaatagcct ctggccacac
      121 ccgctccggc aatgtacagt tctccgatac atccagcagg cagcatccgc tgcttctgat
      181 tgaggatata caatctgaca tgatgaacag attttccaat tggaacgcgt tcaagctttt
      241 catgcagcgg acaatcaaag aacgcagctt ctacagttgc ctccgttggt ccgtaagaat
      301 tggttaatgc aacacctgga agtaactcgc aaaaacggga gacgagatgg gtccccagct
      361 gttctccccc ggaaaacacc cgtttgagtc cgtttatttt aatcggtaca gggcgatatt
      421 ttatatgttc taaaaatgca tgaagcatag atggcacaaa atgcatagct gtgatctctt
      481 gttcttctac agccttcgcg atcacttcag gttctttttc ccctccctga ggaagcagat
      541 aaacagaagc accggcataa ggccaccaaa acagctccca tatggaagcg tcaaatgagt
      601 aagatgtttt atgcataatc acatctgatt gcttcagccg atagcgggac tgaagggaat
      661 tcaaaaaatt caccgcagat cgatgttcaa cttccacacc cttaggcctg ccggtagagc
      721 cggatgtata gatgacatag gctaaagatt tagggagaac gtccacattc ggattggaca
      781 aacgatgttt cagtccgcta tttgcctgat tgaggtagac aatctctcct gcaaatgccg
      841 gaacatgcag gctggaagac tgaagcagga gaatgtctgt accgctgtcc tccagcagaa
      901 agctgattcg ttcttccggg taatccgggt caataggaag ataagcgccg ccagctttaa
      961 gaatgccata aatgccaatc agcatttcag gcgaacgctt tcctataatg gcaacagtcg
     1021 tttcagattt tactcctcgt ccgatcagct cccaggcgat acggttagcc tgttcgttca
     1081 actctttata ggtcatcgct ccatgttcaa agataacggc cggctgatca ggcgtttttg
     1141 ctgcctgctg ttcaagtgca tagtggagag tttgattcat cggatagccc gtctcctgaa
     1201 acggatggca tgattcaatg aaagctctct cttcttcttt tgttaagagt ggaatatcgt
     1261 ccaattctgt tttaggactg acagctgtat gttccacaag cgtggtgaaa aggccggccc
     1321 acctttggat ggtttctttc tcaaacaaag ctgtactgta ttcaaactga cagaaaagct
     1381 cggaatcgtg ttctgtaaca tacagagaaa tatcaaattt cgatattgga tgctgcaaat
     1441 cgttccatcg aagctgtaca tctttcattt tcagcttttg ctgttccata ttctgaagga
     1501 ctagcgttgt gtcaaacaat ggattccggc tcatttcccg ctgcacaccg agtttatcca
     1561 caagctcttc aaacgggtaa tcctgatgct catacgcttc taatgctgtc tgtctgactt
     1621 ctttcagaaa ctcttcaaat gtcatattac cggccgggcg tgtgcggaga gccaatgtat
     1681 tgacgaacat cccaagaaca gcttcaaggt cggcatgggg ccgtccggcg ataggtgaac
     1741 caattacgat atcatcctga ccgcttaacc gcgacaaaaa ggctgaatac aaagcaagaa
     1801 gcgtcatata aagcgtgctt ctgtttttat tggcaagccg ctttatgcgg gccgtgatct
     1861 ctttatccaa ttgaaaggtt acttttccgc ctgtaaagtg ccgttctgcc gggcggcgtt
     1921 tatctgtcgg aagctctagt gcagggaggt ccccgctaaa ctgctgcagc cagtaagtct
     1981 cctgcttttg gtacgagtct ccctttttaa attgctgctg ccaaacggcg taatctttat
     2041 actggatccg caatggctta agctggcggt ttgcataaag atcggtgaat tctcggatta
     2101 ggagctgaac ggatacgcca tctgaaatga tatgatgcat gtcaaccagc aatacatgct
     2161 tctcgttcgt cacttttata aggcccgctc taaataatgg cgcctggctg agatcaaagg
     2221 ggcggataaa cccctcgata gcggtctcta tacttaatgt aaacggcact tcggtgtgga
     2281 tactctgaac aggctcgcca tctgcctcgg atacaaagga agttcgaaga ggctcatgcc
     2341 ggctgatcag ttctttacat acagcagaca gtttagcgac atccagtgcc ccttccagtt
     2401 ctaagaccgc aggcatattg taggcgacac cctcatcaag ctgctgaagc acatatatcc
     2461 gtttttgtgc cgaagataca ggatatgtct tcctttcttc tgccggctca attgctgcat
     2521 acggattttc ctctgcatct tgaatgatta aagccaatcc ttctacagtc ggatgggcaa
     2581 agatgtcctt aagcggaact tgtacatgaa attcctttgc gatccgtgac atcagcactg
     2641 ttgcttttag agagtggcct ccatggtcaa aaaagttgtc ttggatgcct atatgaccat
     2701 tcttcagcac atcttcaaat atttgtgaaa gctttgcctc tatcagatta cgaggggcag
     2761 catatggatt tccgctgatt gaagcatctg gcgctggaag cgctgcttgg tctacttttc
     2821 cgtttggggt aagaggtatg ctgtcaaccc atatccattt cgccggaatc atgtattctg
     2881 gtagctcact agccatatag ctgcgtaaat ctattgcatt cagcttttgt acactgcaat
     2941 agtaagcgca taattcatgt tctccgtttt gatcttgtct gatgagaatg gcagcctctt
     3001 taatgtcccg atgattcatt aacgtgactt cgatttcttg cggctcgatt cgataacctc
     3061 tgattttcac ttgcttgtct gcccgtccta tatattcgat gttgccgtct ccaagccgtc
     3121 tggccaaatc acctgtacgg tacatgatcg caccaggcct gaatgggtca gatgaaaatt
     3181 tgtcgcgtgt cagtttatcg tgattgacat atcctctggc aacacttgcg ccggaaatat
     3241 agagttcacc tggtacaccg catggctgta gctgtttttg gtgattcaaa atatatagat
     3301 cagtacagcc tatcggttta ccgattggcg gaaactcagg aatagggtct cccggatgaa
     3361 tggtgtacgt agataccaca tgagtttctg aaggtccgta atgattgtgc aggtgtatgc
     3421 cgcgttcacg taacacgtct tggaaaatgt ctgaaataat taattgttcc ccagctgtaa
     3481 tcaagtgttt gacgccataa ggaaacgagt tcgcaagttg ccgctcgctg aaaatcattt
     3541 tgataaaagc cgttgggaga aacacaatat tcgtctgatg cttgtttata aatgcaaaca
     3601 gctgaggcac atctcttttt atggcttctg gcacgatgtg cagggtgccg cctttcagaa
     3661 gcgcagaaaa tatttcttga taacagacgt caaaggcagg tgtcgcaaat tgcagaacat
     3721 ctgcttcaaa gtcaatccca gagtgagcaa attcgaactt cagcaagtta gccatgtttc
     3781 gatgttcaaa ttgaacgccc tttggtttac ctgttgtacc tgatgtataa atcagataca
     3841 gcagatcgtc cgcattgtta actgacttta tgttactgcc gtcttctgtg ctttcaatat
     3901 cttctgcatg agtgataagg taattgttat caagcgatgc ggaaagatga gcttgtgaaa
     3961 caacatgcga acagccgcag tcatttagaa tataacggat tctgtcagcc gggtaatgcg
     4021 gatcaattgg aactatggcg ccgcctgctt tcaagatacc aagaaccccg gtgatcaatg
     4081 ccgcagagcg ttccatcatg atcgcaacag gctcctgcct cgcaacaccc ttcattcgta
     4141 aatgccgcgc caatctgtta gccgatttat tcagttcttt gtatgttaac gtgcaggctt
     4201 gatcaattac tgcatgagca tctggggtct tttccgcttg tttttcaaac atcgcatgga
     4261 tggtttcgta aactggcgtt cgatccgcga tttccccaat cagctgccgc ttttcagtat
     4321 ctgtcgtgat ctcgatttct tcaggcggaa gattcggatt atttaagatt tgtgatacag
     4381 cattcagaag atgctccttg acagaaagca caaaagaccg atcatgctgc tccgcatcat
     4441 agctcatttt aatatggatt tcttctcctg gcgccaccat aagataaaag ctgtagttgg
     4501 tttcatctgc cacagtgaag ttatgaatct gaaaaagatc agaagcatgt tcctgcttgt
     4561 tcagcatctg aatctcttgc tgaacaggat agttttcaaa tacgagaata tgatcaatca
     4621 gcccttgttt aacagctgaa cgggcttgaa tctcatataa agggtggtag ctgtatgctt
     4681 cagcggcaag acggtctttt tgcatatctt ttatgagctg tataaatggt gtttttgccc
     4741 cctgcaccct aatcggtatc gtgttaatga aaagacctac catatgttca atgccttcga
     4801 tttctgcggg tcttcctgaa atgacagaac cgaatacggc gtcatcgtta ttattatatt
     4861 tttgaagcag aataccccaa atggtatgga aaatcgtact gagtgttact tcttctcttg
     4921 cagcaagctc cgaaagcctg ctgctttctt ccttagagaa tgaaaacgta acgtgttcct
     4981 gcctgcttct cccctttgtt tttttctgct tcgggagcat ggtttgctgt ccatggccgg
     5041 aaagataatg ttcccaatat gaaactgcct gctctttgtc ttgctccatc agccatttga
     5101 tatagcttcc gtatggctgg accgactcca atgatatagg ggtggcattt acataagatg
     5161 cgtaaatatg gagaaactcc tttagcacaa tgctgaggca ccatccgtcc atcatgatgt
     5221 gatgaaaggt ccaaatacaa gtgtactggc tctctcctgt ttgaatcaga gcgatgcgca
     5281 tgagcatatc cttttgcaag tgaaaccctt gggcgcggtc tttttctttc aattgttcga
     5341 taaactgtgc ttgcttctct tcgtttaaat gagtaatgtc tttttcctgt acgatgatgt
     5401 tccgttctct caggacaacc tgctggggag aggaaacatt ttggctgata aaaatcgttc
     5461 tgaaaatatc gtgtcttgct acaagagcgt tgatgctgtt ttgaaaaaac tgcgagttga
     5521 cttttccttc tattgtaaaa gaagcttgct caacatatgc ctgtgaatct ttttgcagga
     5581 gggaatggaa aagcatccct tcctgcatgt aagacagcgc ataaatatcc tgaattgaat
     5641 tcgcttttgt catgttcatg tctccctgtc cgattttcta caattcttcc accaagctgg
     5701 atatgctgtc caaatcctct gccgttaatg attgactgct aaaatcgctc agtgtctttt
     5761 ctgctttctg tttaccggcg caatgtttca taatgtcccg caaaaagtgt tcaatcctgt
     5821 tgataagctg cttcattgtg tttctatgaa agcgggctgg cggataacta agattgaaat
     5881 ggagcttttt gtctgctgcc attgcactca tctcgatgat ttgctcacgc ttccatgtat
     5941 gagtgatatc ctttccgctc ccaagacttg atgggcggaa gctgtcctgt ctttcgatgt
     6001 cgttgaactg gcccaaatag ttaaagctga tgtcaggtgt ttttgaaaac gcaatgcttt
     6061 tgttttcagg gtgtgtaagg tatttcagaa taccgtaacc tacccctttg tttggtatcc
     6121 ggcccagtgt atctttaacg gtttttactg cggttccgag ctcatcccta tgattttcaa
     6181 agcttatgag ggccgggtac atggatgtaa accagccgac cgtccggctg atatctaact
     6241 ctggcagaat gtgttctctc ccgtgtcctt ccatagcgat acggagcttg cttccgcctg
     6301 tccattcaca aatcgccaag gatgctgcgg ttaacagaat atcttgtgta tctgtaccat
     6361 aggcgtgatt gacgttttgc agcaaaacgg cagtgtctgc ttcagagagt gaaaagcgta
     6421 tcgaatccct tctgctgaag tcggtgttct catgaagcgg catttcatat ggcagttccg
     6481 cagcttgctg ttcttccaca gttcgccaat acgcctcctc acgaatcagc ctgctgcttt
     6541 gggcatattc ctgtatccgt cttgcgtatt cctggtagga atcagtttta ggcggaagct
     6601 gaatcgcctg gcctgaagat gcttgttggt accctgctga caaatcctcc agcaaaatcc
     6661 gccatgccac accgtcaacg acaagatgat ggatcgcaag gaacaagtaa tctcctgtca
     6721 gtgttttaaa ccacgcggca tgtaacaacg gtccttcctg caaattgatg ctttgctgaa
     6781 gatctgcaac ttcttgtttg atttgcgttt cccaaccgct ttcggactgt aaaagatcag
     6841 atattcttaa actgtacagc tgtgattcct gaatgccttg gttgatttga atccatcgcc
     6901 cgtcatcgtt acgataaacc atccgaagcg catcatgatg ctccgccagt ttttttaagg
     6961 ctgctctaag ggcgtcttca gacaaacggt cagaatggaa aagcatgaca gactgattaa
     7021 aatggtgtcg ttcttcaata tcttgtgaaa gaaaccattg ctgaacaggc gtccaaggaa
     7081 cgtctccctg aatggggcct tgttctatga ttctctctgt cttacggata aatggtgata
     7141 agtcttttat ctttggatgc cggaataaat cacttacctg caagcttagc ccatggcgtc
     7201 caaggcgtgc agaaacttga agcgctttga ttgaatctcc gcccaattca aaaaacgaat
     7261 cctctattcc gatcctctgg atgccgagaa cctcctgcca gatcaatgcc agctgttctt
     7321 caaggtcatc gcgtggcggg acgtacgttt gtttagatgc gaaatctggt tcaggaagtg
     7381 ctttccggtt caatttgccg tttgatgtga gcggaagagt ctccatttca atgatgtacg
     7441 ccgggatcat ataatttggc agtgaacgcg cgagaagaga acgcacttgt tcagcattcg
     7501 tgcctgcatt tacgctgatg tagccaaaca gctctttgct ccctgtctgg cctgtacgtg
     7561 ccaacacagc ggcttctttg accccgtcta tttggcgaag tgctgattcg atctcaccca
     7621 gctccacccg atagcctctg acttttactt gatcatctat acggccaacg tactcaattg
     7681 tgccatcggg aagccaacgc gccagatcac ctgtgcggta cagtcgatcg ccaggcgcaa
     7741 atggatttgg gacaaatttc tcttttgtta aatcaggacg gcctaaatag cctctggcga
     7801 cgccatcacc gccgacacaa agttcaccga cagttccgac cggctgcagc attccccatt
     7861 tatttaagat ataagcagtg gaattaccaa ccggccgccc gatcggaatg gaaagttcat
     7921 atgttttttg aatgtggaag catgtcgaaa aagttgtatt ttcggttggt ccatatccgt
     7981 tccatatcga tacttcaggg cagacatttc tgattcgatt gacgtggctt gcggacaagg
     8041 cttccccgcc tataatcaga tgattcagct gtgaaaaggt tgtctcattt tgctctgtca
     8101 aatgattgaa tagagaagat gtcaaccaca tcgttgtgat cccatgaagt tctatgtatc
     8161 tctgaagctg ataggaatcg agaaatactt gtttatcgga caggtgcaaa gctgccccat
     8221 ttagcagcgg tccaaatatt tcaaatgtca caacatcaaa accgattgat gatgtcatga
     8281 gaagacggtc tgccggtgta aatgtaatat aattgctgtt tttaacaaga cgaatgacac
     8341 ttcgctgctc aatcatgaca ccctttggtt taccggttga tccagaggta taaatgatat
     8401 atgcaagtga gtgtgctcct gctgacgatt caaagttctt cgtttctcct tgcttttgaa
     8461 tattttcgat tatgatttgt tcacattcaa tgtctaatag ctgtttttct gttttttcag
     8521 attgaaggag taatgccgcc ccgctgtctg acagcatata agctattcgt tcaacaggca
     8581 ggtcagaagc tataggaaga taggctcccc cggctttcag aatgcccagc attcccgcta
     8641 tgagttctgg cgttcgtcct gtcaacaagg ctacaacacg atcaggccct accccttttc
     8701 tctgtagaac tgaagcaatt tgatttgccc ggctgttcag atccgcgtaa gttaattctt
     8761 gtgtatcgct gacaattgca atggcattag gtgtttgttc agcctgcatt tcaaagagcc
     8821 tgctgatggt ttcatttctt ggataatcta tttttgtatg attgagctca tggataaggt
     8881 aatgggtctc atcctcattt agtatattta ttgttccgag agcggctttg ttgtcttggg
     8941 tgatggagag taacatattg atgaagtatt gaagccactt ttctatcgtt tttttcttat
     9001 ataagtccgt actaaattcc atttggaacg tcagcaaacc gcagggctgt tcgtgagcat
     9061 acagagttaa atcaaatttg gacgtttgat gcccgttgtt tgctgcaggt ttgagatgca
     9121 gttcttcaag ctgaatcgat tcctgatcca tattttgaag aacaaacatc acgtcaaaca
     9181 gcggattccg gctcatatcc cgcgtcaatt taagcttatc gacgagctct tcgaacggat
     9241 aatcctgatg ctcatacgct tccaatgctg tctcgcgcac ttcctgcaaa tactccacaa
     9301 acggcttccc gccctccggg cgtgtccgca gcgccagcgt gttcacaaac atgccgagta
     9361 tcggctcaag atccttgtgc ggccggccgg cgattggcga g
//
