LOCUS       NZ_JALAVX010000005     22954 bp    DNA     linear   CON 26-JAN-2024
DEFINITION  Bacillus subtilis strain EC49O2N-C8 contig_0000005, whole genome
            shotgun sequence.
ACCESSION   NZ_JALAVX010000005
VERSION     NZ_JALAVX010000005.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus subtilis
  ORGANISM  Bacillus subtilis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 121153)
  AUTHORS   Dunlap,C.
  TITLE     Crop Bioprotection Bacillus Genome Sequencing
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 121153)
  AUTHORS   Dunlap,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-FEB-2022) CBP, USDA-ARS-NCAUR, 1815 N. University St.,
            Peoria, IL 61604, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC NGS Cell v. 21
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 62.01322621364343x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/24/2024 02:42:56
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,133
            CDSs (total)                      :: 4,055
            Genes (coding)                    :: 3,871
            CDSs (with protein)               :: 3,871
            Genes (RNA)                       :: 78
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 184
            CDSs (without protein)            :: 184
            Pseudo Genes (ambiguous residues) :: 0 of 184
            Pseudo Genes (frameshifted)       :: 97 of 184
            Pseudo Genes (incomplete)         :: 98 of 184
            Pseudo Genes (internal stop)      :: 21 of 184
            Pseudo Genes (multiple problems)  :: 27 of 184
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:11:08
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7731
            Orig. end                         :: 30685
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JALAVX010000005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22954
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="sactipeptide"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     cand_cluster    1..22954
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="interleaved"
                     /product="sactipeptide"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..22954
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:12954](+)"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12954
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     gene            36..178
                     /locus_tag="MOE40_RS02205"
                     /old_locus_tag="MOE40_02205"
                     /pseudo=""
     CDS             36..178
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009513939.1"
                     /locus_tag="MOE40_RS02205"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="MOE40_02205"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSKRERTSTVEKWIKEGDGTGTGTDYRPWLKIQDVSSLGRSTRLK
                     GI"
     protocluster    235..21467
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10234:11467](+)"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      10235..11467
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="2"
     gene            complement(432..>698)
                     /locus_tag="MOE40_RS02210"
                     /old_locus_tag="MOE40_02210"
                     /pseudo=""
     CDS             complement(432..>698)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388061.1"
                     /locus_tag="MOE40_RS02210"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="MOE40_02210"
                     /product="DNA-3-methyladenine glycosylase"
                     /pseudo=""
                     /transl_table=11
                     /translation="QAYGLRVIGIPDLFEALCWGVLGQQINVLMRCLRFPTAFPIDDVG
                     LIHSIKILRNMNRKPTKDEILEISFSWKTWESYATFYLWRVLY"
     gene            <692..1051
                     /gene="adaB"
                     /locus_tag="MOE40_RS02215"
                     /old_locus_tag="MOE40_02215"
                     /pseudo=""
     CDS             <692..1051
                     /codon_start=1
                     /gene="adaB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388063.1"
                     /locus_tag="MOE40_RS02215"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="MOE40_02215"
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /pseudo=""
                     /transl_table=11
                     /translation="KLEPYAVEITQYLEGKRKNFTVPVEYAGTQFQLAVWNSLCEIPYG
                     QTKSYSDIANDINKPAAVRAVGAAIGANPVLITVPCHRVIGKNGSLTGYRGGFEMKTLL
                     LDLEKRASSEMDVPH"
     gene            1570..3087
                     /gene="ndhF"
                     /locus_tag="MOE40_RS02220"
                     /old_locus_tag="MOE40_02220"
     CDS             1570..3087
                     /EC_number="1.6.5.9"
                     /codon_start=1
                     /gene="ndhF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388064.1"
                     /locus_tag="MOE40_RS02220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE40_02220"
                     /product="NADH dehydrogenase subunit 5"
                     /protein_id="WP_217001285.1"
                     /transl_table=11
                     /translation="MLVSLSLSSLLTLFFIMLMASGISGLLFLHPRVPLSFVRIHIGIL
                     ALPLLVSLLILANSGVSGNVGPWHLDSLACLMTFFVLAIGFIIQRFSVRYLMGDRSYRK
                     YFTLFTFTTGAASMTWLSGDLRLMVLFWGATLVGLTLLIRLNSAWQVASEAAKISGRLF
                     LLSWFSLFFAMMWLFHATGQWQLSLVVTNESLAGLGEWERTGIQLLIVLAVIIPAAQWP
                     FQRWLVESIVAPTPVSAIMHAGLVNAGGIILTRFSPLFHGGIASIILLLLAGISVLIGT
                     GISLVQVDYKRQLVGSTIGQMGFMLIQCALGAYIAAIIHLILHGLFKATLFLQAGSSVG
                     RHEVSARTNERTSYIWVMAGRILSLFIGVAFWLAAPGEGYQFISALILGWSLSVSWTQL
                     VAFGEGRIGRIAGLTVLGGAALVYFIIHNLFYKWLHTTIFQSVQPPMSAVMIVVCLLLF
                     GSALGTWVARHRSSVFFAVLYLWLVRLGEAKPKSVESHPDYLKQYIS"
     gene            3102..5717
                     /gene="ybcC"
                     /locus_tag="MOE40_RS02225"
                     /old_locus_tag="MOE40_02225"
     CDS             3102..5717
                     /codon_start=1
                     /gene="ybcC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388065.2"
                     /locus_tag="MOE40_RS02225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE40_02225"
                     /product="YbcC family protein"
                     /protein_id="WP_217001287.1"
                     /transl_table=11
                     /translation="MGITSVLTKDNVKKIDTDIDVQERDLNVFITSASRVIAPLWPIST
                     FAARNPWMGLENQPFDQVASWLKNTRDVDIYPSASMIRSAKKKGEIDEDFVEMGLQRWL
                     DSHSFHIPGDVAERFCHAALKLDPLPSDLLSSHELEKLVGECSGLDHIENVFMQPLSSH
                     IENQDGERLVNILDHHVIKWSKLYLDDSQAGWTMPNREEGFYRAWQHLIQYDPALSKKQ
                     RERLKGWPKEAHLALQEVLFALEIPESEIQTYLEGHLLSLPGWAGMMLWRSQQSSHEHA
                     LLTEYLAVRISMEWALIKPYLPLTNERSKKTISIAPLIAAWIHWGGLTLEEWSQMTAIE
                     QNEYLSFAYSFDEKLRKKLWLEAWEQTYTDRLSQKIISKQRETGGKKSALAQLAFCIDV
                     RSEPFRRQLEKEGPFETIGIAGFFGVPIATCELGSKHSHASLPIIQKPQNKIKEFADED
                     VFKKYNQRKQAIHSLSHTFKTMKQNALSSLLLPELSGPWLTLQMAARSFVPRKAGRFIR
                     NLREAWLRKPDTKLSLHHDATEAEIPVGFTDEEKVNYARQALKMMGLTENIAPLVVICG
                     HGSQSTNNPYSAALDCGACGGAAGGFNARVLAALCNLSEVREALLAEGIQIPEDTVFAA
                     AEHNTTVDELHWLYVPELSEAAQEAFEQIEAVMPKVRHHVNAERLDQLPNFQSKLKNPK
                     AEANRFAEDWSEIRPEWGLARNAAFIIGKRELTQDCDLEGRAFLHNYDWKQDESGELLA
                     NIIAGPGTVAQWINLQYYASTVAPHYYGSGNKATQTVTAGLGVMQGNASDLLAGLPWQS
                     VMESDHEAYHSPLRLLILIQAPREYVERLLNHDSAFLQKVQNGWVRLASIDPEGCWESW
                     "
     gene            5794..6321
                     /gene="ybcF"
                     /locus_tag="MOE40_RS02230"
                     /old_locus_tag="MOE40_02230"
     CDS             5794..6321
                     /codon_start=1
                     /gene="ybcF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388067.1"
                     /locus_tag="MOE40_RS02230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE40_02230"
                     /product="carbonic anhydrase"
                     /protein_id="WP_217001289.1"
                     /transl_table=11
                     /translation="MNVNQNKKVLFLTDIENGLEPILQEATNTSAENMLTIQSYGAGIS
                     HPYGEIMRSVIFAIYQEDVEEIFVVGTKDKKTSAGNGLTQLETMKDKIQTLDYLFQNCK
                     PEFLGGTVDEWLNENSSDTIEKSVDMIRRHPLVPSYVKVRGLLVNHKDGRPSIVEDPAI
                     KTGQAIPDHCLS"
     gene            6383..6673
                     /gene="ybcH"
                     /locus_tag="MOE40_RS02235"
                     /old_locus_tag="MOE40_02235"
     CDS             6383..6673
                     /codon_start=1
                     /gene="ybcH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388068.1"
                     /locus_tag="MOE40_RS02235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE40_02235"
                     /product="DUF6407 family protein"
                     /protein_id="WP_015252954.1"
                     /transl_table=11
                     /translation="MSANLTDFVTKTIEDMNSFDRENMECMKKLIRKAIDFYHLKSYEE
                     VEETHSGNVRFLHVHSMMEENMLSKMIVVTRNGKTDLDIEGVYEGYVVREY"
     gene            6730..7092
                     /gene="ybcI"
                     /locus_tag="MOE40_RS02240"
                     /old_locus_tag="MOE40_02240"
     CDS             6730..7092
                     /codon_start=1
                     /gene="ybcI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019257313.1"
                     /locus_tag="MOE40_RS02240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE40_02240"
                     /product="DUF2294 domain-containing protein"
                     /protein_id="WP_015715144.1"
                     /transl_table=11
                     /translation="MKKSKGSIESEISKSITQWEKDYLGRGSVSVKTDILRDMIIVNLK
                     GILTPAEYVVCGSKEGMLSIKQTRSELVESGIEGLKDIILKITGEKVKSFHTDLSSRTG
                     ERVMVFKLCNDLEKNL"
     gene            7553..7855
                     /gene="ybzH"
                     /locus_tag="MOE40_RS02245"
                     /old_locus_tag="MOE40_02245"
     CDS             7553..7855
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="ybzH"
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_003097670.1"
                     /locus_tag="MOE40_RS02245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE40_02245"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_003234907.1"
                     /transl_table=11
                     /translation="MEPIEVFKALSNESRLQILQWLKEPDRHFAPHEGIDMNTIGVCVS
                     QITDKLKMTQSTASQYLTILLRAGLIKAERIGKYTYYKRDEEAIGKLADFLKTEI"
     gene            7982..9154
                     /gene="ybcL"
                     /locus_tag="MOE40_RS02250"
                     /old_locus_tag="MOE40_02250"
     CDS             7982..9154
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="ybcL"
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388070.1"
                     /locus_tag="MOE40_RS02250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE40_02250"
                     /product="MFS transporter"
                     /protein_id="WP_187954594.1"
                     /transl_table=11
                     /translation="MSNTWKIYILAIVSFLVGTSEYIISGILDQIAHTLGITLAAAGQL
                     ITIFSLVYALSTPVLMALTASMDRRKLMMYALGLFVFGNVLAFVLPGYGWFIAARIIMA
                     MGAGVVVVTALTIAAKIASEGKQGSAIATVVMGFTASLIIGVPLGRMIAVALGWKSVFG
                     AIALLGLIAMVVIFFTLPHTEGDKPVPLLQQLALFKKRKVAMGLSITFFWLGGYSVAYT
                     YLSPYLLNISGINGKLLSGVLLIFGIASLVGSKFGGYSTDKWGVSFTLVGGMTLHIVTL
                     ILLSLVTHSYIGVLVILILWSFAAWSTGPTQQFHLATIEPEMSGVLLSMNQSMMQFAMA
                     VGAGIGGVFVENVSLTSITWVGALGVMIAIITSLTIFHSQPKQTLKDINQ"
     gene            <9255..>9602
                     /locus_tag="MOE40_RS02255"
                     /old_locus_tag="MOE40_02255"
                     /pseudo=""
     CDS             9255..>9602
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003223659.1"
                     /locus_tag="MOE40_RS02255"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="MOE40_02255"
                     /product="glutamine--fructose-6-phosphate aminotransferase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MCVEGALKLKGIS"
     gene            10001..10168
                     /gene="skfA"
                     /locus_tag="MOE40_RS02260"
                     /old_locus_tag="MOE40_02260"
     CDS             10001..10168
                     /codon_start=1
                     /gene="skfA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: TIGR04404"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388072.1"
                     /locus_tag="MOE40_RS02260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE40_02260"
                     /product="sporulation killing factor"
                     /protein_id="WP_009966416.1"
                     /sec_met_domain="TIGR04404 (E-value: 1.3e-38, bitscore:
                     123.7, seeds: 3, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRNQKEWESVSKKGLMKPGGTSIVKAAGCMGCWASKSIAMTRVC
                     ALPHPAMRAI"
     aSDomain        10235..10537
                     /aSDomain="Other_Sactipeptide_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a sactipeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_MOE40_RS02265_Other_Sactipeptide_rSAM
                     _RRE.1"
                     /evalue="1.70E-16"
                     /identifier="RREFam021.1"
                     /label="MOE40_RS02265"
                     /locus_tag="MOE40_RS02265"
                     /protein_end="101"
                     /protein_start="0"
                     /score="51.4"
                     /tool="antismash"
                     /translation="MSYDRVKDFDLPELAVHLQPHGAVMIDRKSMFYFRLSGRGAQLAF
                     LLSKNKNLHKTARIWEIMKKEEMSADQLKEELSAHPFTEAWTEGLLDQPLHVSGSL"
     gene            10235..11467
                     /gene="skfB"
                     /locus_tag="MOE40_RS02265"
                     /old_locus_tag="MOE40_02265"
     CDS             10235..11467
                     /codon_start=1
                     /gene="skfB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Other_Sactipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388073.2"
                     /locus_tag="MOE40_RS02265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE40_02265"
                     /product="sporulation killing factor system radical SAM
                     maturase"
                     /protein_id="WP_268548093.1"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     7.4e-16, bitscore: 51.4, seeds: 13, tool:
                     rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 2.9e-32, bitscore:
                     104.9, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 7.8e-23, bitscore: 74.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.4e-07, bitscore: 24.8,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.4e-06, bitscore: 21.7,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYDRVKDFDLPELAVHLQPHGAVMIDRKSMFYFRLSGRGAQLAF
                     LLSKNKNLHKTARIWEIMKKEEMSADQLKEELSAHPFTEAWTEGLLDQPLHVSGSLDSY
                     LPISCTLQLTNACNLSCSFCYASSGKPYPEELSSEQWILVMQKLAAHGVADITLTGGEA
                     KLIKGFKELVVVASSLFTNVNVFSNGLNWRDEEVELLSHLGNVSVQISIDGMDNTHDQL
                     RGRKGGFKESMNTIKKLSEANIPVIVAMTINESNADEVSDVVEQCANAGAFIFRAGKTL
                     SVGRASEGFKALDIDFEEMVQIQLREARHKWGDRLNIIDWEHEESSFTTDFCTPGYLAW
                     YIRADGYVTPCQLEDLPLGHILEDSMADIGSPARLLQLKCEAKNCKCIGKIELSEPDLP
                     FQKEFKAGIQE"
     gene            11464..12954
                     /gene="skfC"
                     /locus_tag="MOE40_RS02270"
                     /old_locus_tag="MOE40_02270"
     CDS             11464..12954
                     /codon_start=1
                     /gene="skfC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: skfc"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_003097671.1"
                     /locus_tag="MOE40_RS02270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE40_02270"
                     /product="sporulation killing factor biosynthesis protein
                     SkfC"
                     /protein_id="WP_268548094.1"
                     /sec_met_domain="skfc (E-value: 3.1e-289, bitscore: 952.9,
                     seeds: 3, tool: rule-based-clusters)"
                     /sec_met_domain="Abi (E-value: 3.1e-14, bitscore: 46.2,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSLSLVFWSILAVVGLLLFIKFKPPTIASLLLSKDEAKEISIQF
                     IKEFVGIDVENWDFYSVYWYDHDTVNKLHHLGILKKNRKVLYDVGLVESWRVRFVHQNQ
                     SFVVGVNANREITFFYADVPKKTLSGKFEQVSPETLKQRLMASPDGLWSRANMTGTGKK
                     EEDFREVSTYWYIAEAGDIRLKVTVELQGGRISYVGTEQEILTDQMSKVIRDEQVESTF
                     GVSGMLGSALAMILAILILVFMDVQTSIIFSLVLGLLIIICQSLTLKEDIQLTIVNAYD
                     ARMSVKTVSLLGILSTLLTGLLTGFVVFICSLAGNALAGDFGWKTFEQPIVQIFYGIGA
                     GLISLGVTSLLFNLLEKKHYLRISPELSNRTVFLSGFTFRQGLNMSIQSSIGEEVIYRL
                     LMIPVIWWMSGNILISIIVSSFLWAVMHQVTGYDPRWIRWLHLFIFGCFLGVLFIKFGF
                     ICVLVAHFIHNLVLVCMPLWQFKLQKHMHHDQPKHTSL"
     gene            12973..13695
                     /gene="skfE"
                     /locus_tag="MOE40_RS02275"
                     /old_locus_tag="MOE40_02275"
     CDS             12973..13695
                     /codon_start=1
                     /gene="skfE"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388077.1"
                     /locus_tag="MOE40_RS02275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE40_02275"
                     /product="sporulation killing factor ABC transporter
                     ATP-binding protein SkfE"
                     /protein_id="WP_268548095.1"
                     /transl_table=11
                     /translation="MQLMQVQNLSKCYRNGDGVEHLSFSIQRGEIVALLGPNGAGKTTT
                     IRCLTGLYKPDKGDILIEGSPPGHINVQKKVALIPDQPYLYPALTAAEHIQFRARGYHP
                     GKKDVKERVYHALKEVHLEEKANQLCGQLSRGQKQRVVLAGAIVQDALLYILDEPTVGL
                     DIPSKQWLSNWLKTKTDQGCSAFVSTHSLEFVIETADRVILIRDGKLMQDLYVPQFEEE
                     QAEWRKEVIRLLGEWSDE"
     gene            13688..15103
                     /gene="skfF"
                     /locus_tag="MOE40_RS02280"
                     /old_locus_tag="MOE40_02280"
     CDS             13688..15103
                     /codon_start=1
                     /gene="skfF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019257319.1"
                     /locus_tag="MOE40_RS02280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE40_02280"
                     /product="sporulation killing factor system integral
                     membrane protein"
                     /protein_id="WP_268548096.1"
                     /transl_table=11
                     /translation="MNNIISFLWLQSKRRFVSQGQEKKMPFLIMLLFVGAIGFQVSFVS
                     RSTTWDMSIAGWVLTGVFILYTAFGLFSNRLPSQMADIIWLYGTATSFSKVVYSVLFFS
                     VTWKALLWIISAIFGDVLIVLLSGEHINLLGRSIIFVGLFFIAEVWLMSVSCARTVKKM
                     KRVYVLVFLLMLGIYSICLYHFFFLQHSSGIWESIARFISGVGLVFDTLSPLYVVVFIG
                     IITVSFMTIAFTSRQVEMKESLVKEAEFWEEFQERQFGSGQIIQKPKTTWWGLQGLNGI
                     WSFLWLELLLFKKYLFFHSIHTVMLSGVFYVVIFMYPEWFYLLFFLIVSAVMLSSYYSG
                     IVRHSQSGTLHLFPGALWKKIIILELTNTVWLYILYCVSITFMAVGNLVYWYIYGLGIY
                     IWFMTIRLFAFTHTNRNDIKLSLPQYYKSFFMALGLSGICLYVIHLLTADWYTLVVVVC
                     IGSLSWCLFYRFR"
     gene            15150..15665
                     /gene="skfG"
                     /locus_tag="MOE40_RS02285"
                     /old_locus_tag="MOE40_02285"
     CDS             15150..15665
                     /codon_start=1
                     /gene="skfG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388079.2"
                     /locus_tag="MOE40_RS02285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE40_02285"
                     /product="sporulation killing factor biosynthesis/export
                     protein SkfG"
                     /protein_id="WP_003234897.1"
                     /transl_table=11
                     /translation="MNSNGDKLSLSVQNLANTNEITIVQAIGELKKSGKDAIPVLVEAL
                     KEEGSLCNIAAAVLGEFGEDASEAAEELSCLLKSHAEDTRMAAAISLMRIGKPSLPFVI
                     KIAQESEGQSCFWASWCIAWIDPSCIEPKMYKCLKYEHEHPSGIVAPFAAEEALGKLIA
                     FQLKDKED"
     gene            15670..16095
                     /gene="skfH"
                     /locus_tag="MOE40_RS02290"
                     /old_locus_tag="MOE40_02290"
     CDS             15670..16095
                     /codon_start=1
                     /gene="skfH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388080.2"
                     /locus_tag="MOE40_RS02290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE40_02290"
                     /product="sporulation killing factor biosynthesis/export
                     protein SkfH"
                     /protein_id="WP_003246390.1"
                     /transl_table=11
                     /translation="MKDEQMLTEWPSHLPWLNQSQNDFTFPSDTYLLLYFWSMSCPNCH
                     QLTDKVLQDIKDMNVKVIGVHVPYIEEEKSMEVVLTYALDRGLAIPIVLDQNYEIVTTC
                     HVQGIPSFCLLSQYGQIITKTMGDVGWDKMLKKIAGL"
     misc_feature    15688..15703
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.76"
                     /tool="antismash"
     gene            16344..17321
                     /gene="ybdG"
                     /locus_tag="MOE40_RS02295"
                     /old_locus_tag="MOE40_02295"
     CDS             16344..17321
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="ybdG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388081.2"
                     /locus_tag="MOE40_RS02295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE40_02295"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_015382623.1"
                     /sec_met_domain="PF00561 (E-value: 1.6e-08, bitscore: 27.4,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTLWKVLKIVFVSLAALVLLVSVSVFIYHHFQLNKEAALLKGKG
                     TLVDVDGKKMNVYQEGSGKDTFVFMSGSGIAAPAYEMKGLYSKFSKENKIAVVDRAGYG
                     YSEVSHDDRDIDTVLEQTRKALMKSGNKPPYILMPHSISGIEAMYWAQKYPKEIKAIIA
                     MDIGLPQQYVTYKLSGVDRLKVRGFHLLTSIGFHRFMPSAVYNPEAIRQSFLTDEEKEI
                     YKAINFKQFFNADMEHELLQSYQNGSKSVNLPAPKETPVLILDAVSDQNRHSKYAIQNR
                     KDYEAFAAQFNTADIKELRGTHSIYLYQPDQIYKLSMEFMRKVR"
     gene            17323..17994
                     /gene="ybdJ"
                     /locus_tag="MOE40_RS02300"
                     /old_locus_tag="MOE40_02300"
     CDS             17323..17994
                     /codon_start=1
                     /gene="ybdJ"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388082.1"
                     /locus_tag="MOE40_RS02300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE40_02300"
                     /product="two-component system response regulator YbdJ"
                     /protein_id="WP_268548097.1"
                     /transl_table=11
                     /translation="MKGYHILIVEDDVMIGDLLQKILQREGYRVIWKTDGADVLSVIQK
                     VDLVIMDVMLPGEDGYQMSAKIKELGLGIPVIFLSARNDMDSKLQGLQIGEDYMVKPFD
                     PRELLLRLRNMLEHHYGTFTQIKHLYIDAVTKKVFNESLHDEVLFTAIERKIFFYLYEN
                     RDSILTKEHFFEYLWQLEDRNPNIVNVHIKKIRAKINDQAGEMIENIYGEGYRLNTVVK
                     K"
     gene            17991..18977
                     /gene="ybdK"
                     /locus_tag="MOE40_RS02305"
                     /old_locus_tag="MOE40_02305"
     CDS             17991..18977
                     /codon_start=1
                     /gene="ybdK"
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234894.1"
                     /locus_tag="MOE40_RS02305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE40_02305"
                     /product="two-component system sensor histidine kinase
                     YbdK"
                     /protein_id="WP_268548098.1"
                     /transl_table=11
                     /translation="MKLKTKYQLLLFTAVISVPVLLLAVSVLMSVIYDSMFKTMNHGMP
                     FHRSFAYPAMIVVFLISLLLLAFLFSKSIHSLLHKINLLNQTIRHLASDQRVPDKIEVK
                     RADEIGELIKSVNLLIERTTYRELELRQQEEIKKELLQKLRHDINTPLTALRLQLFYLE
                     DQCHGQAVFESLYQQIEYISELTNEFNLYSAETLESSYIVNEEVRLNELLETAVKKWDY
                     LYSMSGIELHYKPADQDVIWMSNALWMQRLFDNIFQNTLKHSKAEKMEVTIEHGDVFIR
                     DDGIGFDRNESSEGLGLKIIEDTCRLLAITYELHTNDNGTGFLFSKE"
     gene            19017..19298
                     /locus_tag="MOE40_RS02310"
                     /old_locus_tag="MOE40_02310"
     CDS             19017..19298
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_003097672.1"
                     /locus_tag="MOE40_RS02310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE40_02310"
                     /product="hypothetical protein"
                     /protein_id="WP_268548133.1"
                     /transl_table=11
                     /translation="MGERNGVNSICLKKSSKRLSTSQAVLVTDIADTGITAAVGADIIA
                     ATAAVRAKEDTTTVMAAVIVTNAGATAAVNPKKVLVPLLGQGFFYVTD"
     gene            complement(19283..20053)
                     /gene="ybdM"
                     /locus_tag="MOE40_RS02315"
                     /old_locus_tag="MOE40_02315"
     CDS             complement(19283..20053)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="ybdM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388085.1"
                     /locus_tag="MOE40_RS02315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE40_02315"
                     /product="protein kinase"
                     /protein_id="WP_268548099.1"
                     /sec_met_domain="Pkinase (E-value: 7.4e-34, bitscore:
                     110.2, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALKLLKKLLFDRPLKNGVILNHQYKIEECLGMGGYGLVYLCTDI
                     LTQTPYVLKQLRPTKAKKEKEKVRFQQEIKLLKSIHHPQIPGFIDEFIIDGQAYYVMQF
                     IEGENIEELLFFRKQPFTELMALQLISQLLEIIEYLHDRLIFHSDIRTPNIIINDGRLC
                     LIDFGLAKQLTPEEMEEIKVRKQDDFFDLGETLLFLLYSQYKGKKKKNGTWLEELTLTK
                     EVTLLLKRLLGIEEEYQHTASIREDLNWAIQSVT"
     gene            complement(20139..20996)
                     /locus_tag="MOE40_RS02320"
                     /old_locus_tag="MOE40_02320"
     CDS             complement(20139..20996)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388086.1"
                     /locus_tag="MOE40_RS02320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE40_02320"
                     /product="hypothetical protein"
                     /protein_id="WP_123374006.1"
                     /transl_table=11
                     /translation="MVKKWLIPFAVMLSVLFTFTYSASAVGVTAITGNNSFDTAMPIGY
                     WKYKNIDTTILEAGQDEAYFTFTANKGEKVYVRSTYQSAYTGMKIEIYDKNRIPVSQGT
                     EVINPNTFSSFIYANADAQNTTDTFYVKVSRGTYTGNMYFTLSIEDRIKSGSGTFQFSG
                     VAENKGNTSLSPSGSDSSVIKVDLTNQSGIPRDAIVTRVQTTATQTPSQGNTRHLIMTS
                     ENNEWRRALVNSSTSGSYDISLSDQLSVAKVWSFKYNTLATARSTMSNVKAKIDYEYDV
                     TKQF"
     misc_feature    21053..21062
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     gene            21128..22312
                     /gene="ybdO"
                     /locus_tag="MOE40_RS02325"
                     /old_locus_tag="MOE40_02325"
     CDS             21128..22312
                     /codon_start=1
                     /gene="ybdO"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388087.1"
                     /locus_tag="MOE40_RS02325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE40_02325"
                     /product="DUF4885 domain-containing protein"
                     /protein_id="WP_268548100.1"
                     /transl_table=11
                     /translation="MRLNRQFIRTQLMAQNILSKNAPAKRENATENPAAVLEKAYSRLK
                     SQSSTGGINQFNYSKTGVSGNSGTFSKVYQSANDRTVTDTGEETVIQSQNPYESESDIR
                     IKILDEKYSRMNAINKTKSDPLGYIKDKYQNSKSPYFRSDLSAAERQAAYDNETEWLFK
                     GKAQNYNLQDAAFRNVTFHGEVEAENEKVYQRGQVNQQLQVLLNRNHIHIPEGTELTFT
                     ITPIDYQVRVSGTDDQDLIKQIEQVLQSGDNSKELFLHIMKSQSPDSAQFSEEAYQKYQ
                     AAREMYEVTGYHLKDLEVIDGRYVTPDGRDLIDVYKEELEKDPVQKQTASYAISYYRSE
                     LSKIAEAGYNAIPDFILSIDYSNGSLRDVGQSKSYGTGDTGWLEALKRQTGVNY"
     misc_feature    22373..22387
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.38"
                     /tool="antismash"
     misc_feature    22393..22406
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.64"
                     /tool="antismash"
     misc_feature    22852..22866
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 18.76"
                     /tool="antismash"
ORIGIN
        1 cccctttgga taagattgtc taaaggggtg tttttatgtc caaaagagaa agaacatcta
       61 cagtggaaaa atggattaaa gaaggtgacg gtacaggaac aggtacagac tatcggccat
      121 ggctaaagat tcaagatgtt tcctcattag gtcggtcaac gaggttaaaa ggcattaaga
      181 cttggagcaa aactgttttg cctaactgag ttttctgatg ttattacaga tataagagag
      241 cagttcctca ttaagatacg cttttgatag cagttggaat aaagcatgct aaaatccgaa
      301 aaacggagag cctattgtaa tgacaccgat tttttattga caattaataa aggcaaagaa
      361 ttcttgaagt cgtacgcaca atgtacttgt gggatgtagg ttttaaagtt cattctttaa
      421 gttgaaatga ttcagtaaag gacacgccat aaataaaagg tagcgtatga ctcccatgtt
      481 ttccatgaaa acgatatttc taagatttca tctttcgtag gctttcgatt catattacgt
      541 aatattttta tcgaatgaat tagacccaca tcatcgattg gaaaagctgt cgggaaccta
      601 aggcagcgca ttagaacgtt aatttgttgt cctaaaactc cccaacataa agcttcaaat
      661 aaatcgggaa tgccgataac tcgcaaccca taagcttgaa ccctatgctg ttgaaatcac
      721 tcaatatcta gaaggaaagc ggaaaaactt tactgttcca gttgagtacg ccggtacgca
      781 atttcagctt gcagtctgga attcactttg tgaaattcct tatggacaga cgaaatccta
      841 ttccgacatt gcaaatgata taaataaacc agcagctgtt cgtgctgtag gtgcggctat
      901 tggggctaat ccggtattaa ttactgtacc gtgccatcgt gtaataggaa agaatggctc
      961 attaactggc tatcggggcg gatttgaaat gaagacactg ctcctcgatc tggaaaagcg
     1021 agcttcatct gaaatggatg ttcctcattg aaagtgaatc atctataatg ggttggatta
     1081 ttttagagga aagtaaagac cagtttactg ataaacttga caacttttaa aatttagcat
     1141 atcttatacg taacttaata atcgatgccg atgtttattt ttccttttaa aatatgtagg
     1201 cctttagcat tcttttcata tttaatttta aatattgata ggatgaaaaa gcatcctaac
     1261 taaaaaggaa gagaaacata agtcgattta tttgataatc aggactatat taaaggaaat
     1321 taaacatagc ataaagtaaa gaccaataat aaggtagctc ttcaaaaaac ttcgctgaag
     1381 ttagttgaag tgaagccgac aattttcagg attcaatgat ctaacataat cattgaaatt
     1441 ttgaagttgt cggctttttt gttggaaaaa aatagagata aataaaaatt gaaataaata
     1501 ataaacaaat atgatctgat tgaaaggtct tttgaccaat aatgagtttt aaaaaaggga
     1561 gaatttagaa tgttagtttc gctgagtttg tcatcattat taacattgtt ttttattatg
     1621 cttatggctt ctgggattag tggactattg tttttacatc cgcgagtacc cttgagtttt
     1681 gttcgcattc atattgggat cttggcttta ccacttttgg tttccttact gattcttgcc
     1741 aatagtggtg tgagtggaaa tgttggccct tggcacttag attccttagc ttgtttaatg
     1801 actttctttg ttcttgcaat tggattcatc attcagcgtt tttctgtacg ttacttaatg
     1861 ggggatcgat cttatcgaaa atattttacg ctttttactt tcacaacagg agctgcttca
     1921 atgacatggt taagtggtga tctccgcttg atggttctat tttggggagc aactcttgtt
     1981 ggtttaacct tacttataag gttaaacagt gcttggcaag tggctagtga agcagccaaa
     2041 atttctggcc ggttattttt gttaagttgg ttttctttgt tttttgcgat gatgtggctt
     2101 tttcatgcca caggtcaatg gcagttatca ttggttgtaa caaatgaaag tttagctggg
     2161 ctgggagaat gggagagaac agggattcag ctattgattg tactggcggt gatcattcct
     2221 gcagctcaat ggccgttcca aagatggttg gttgagtcta ttgttgctcc aacccctgtt
     2281 tctgcaatta tgcatgcagg tttagtaaat gctggaggaa taatactaac tcgattttca
     2341 cctctatttc atggtggtat cgcttcgatt atcttacttc tgcttgctgg catttctgta
     2401 ttgattggaa ctggaattag tttagtccag gttgattata aacgccagtt agtaggctcc
     2461 acgattggac aaatggggtt tatgctcatt cagtgtgcat taggcgccta tatagcagcc
     2521 attattcatc ttattttaca tggtttattc aaagctacgt tgtttctaca agctggttca
     2581 tcagtagggc gtcatgaagt atcggctcgt actaatgaaa gaacatccta tatatgggtc
     2641 atggctggtc ggattttatc cttatttata ggcgttgctt tttggctcgc tgctcctgga
     2701 gaggggtatc aattcattag tgcgctgatc ttagggtggt cattgtccgt ttcttggact
     2761 cagcttgtcg cttttggaga gggccgaatt ggccgaattg ccggcttaac tgttttagga
     2821 ggagcagccc tcgtatattt tatcattcat aaccttttct ataagtggct gcatacaacc
     2881 atttttcaaa gtgttcaacc tccaatgtca gctgtcatga ttgtcgtatg tctcttacta
     2941 tttggcagtg ctttaggtac gtgggttgct cgtcatcgtt cttccgtttt tttcgcggta
     3001 ctctatcttt ggttagttcg attaggtgaa gcaaaaccaa agtcagtaga gagtcaccca
     3061 gactacctta aacaatatat ttcataagga gctaatctga gatgggcatt acatccgtat
     3121 taacgaaaga taatgtaaaa aagatagata cagatattga tgttcaagaa agggatctta
     3181 acgttttcat tacatctgcc agccgagtga ttgcgccact ttggcctatt tctacatttg
     3241 ctgcacgtaa tccgtggatg ggacttgaaa accaaccttt tgatcaggtt gcaagttggt
     3301 tgaaaaacac tcgcgatgtt gatatatacc ctagtgcgtc tatgatccgt tcagcaaaga
     3361 aaaaaggtga gattgatgaa gattttgtgg aaatggggct gcagcgttgg cttgattcac
     3421 attcctttca catcccaggg gacgtggcag agcgattttg tcatgctgca ttaaagttag
     3481 atcccctgcc ttccgacctt ttatcatcac atgagctgga gaaattagta ggtgaatgta
     3541 gtggattgga tcatatcgag aatgttttta tgcagccact aagttcgcat atagagaatc
     3601 aagatggtga aaggctagtc aatatactag atcatcatgt cattaagtgg agtaaattat
     3661 atcttgatga ctctcaagca ggctggacaa tgcctaatcg tgaggaaggt ttctatcgtg
     3721 cttggcagca tctcattcaa tatgatccag cacttagcaa aaagcagcga gaaaggttaa
     3781 agggttggcc gaaagaggca catttggctt tacaggaagt cttattcgca ctagaaatcc
     3841 cagagtcaga aatccagact tatcttgaag gtcatttact ttccttacct ggatgggcag
     3901 ggatgatgct ttggcgctcc cagcaatcga gccacgaaca tgcactccta acagaatatt
     3961 tagcggttcg aatatccatg gagtgggctc ttataaagcc atacttacct ttgactaatg
     4021 aacgatctaa gaaaacaatt tcaattgctc cccttatagc agcttggatt cattggggtg
     4081 ggcttacatt agaagaatgg tcacagatga cggccattga acaaaacgaa tatttatcat
     4141 ttgcctacag ctttgatgag aaacttcgca agaaactttg gttagaagct tgggaacaaa
     4201 cgtacactga tcgattaagc cagaagatca tctcgaaaca acgtgaaacc ggcggtaaaa
     4261 aatctgcatt agctcaatta gcattctgca tcgatgtacg atcagaacct tttcgtcgtc
     4321 aactagaaaa agaaggcccg tttgaaacga ttggtattgc tggtttcttc ggggtgccga
     4381 ttgcaacttg tgaacttggc agtaaacaca gtcatgcttc cttgccgatc atacaaaaac
     4441 ctcaaaataa aataaaagag ttcgcagatg aggatgtatt caaaaaatac aatcaacgga
     4501 agcaagcaat tcattcttta agccatacct ttaaaacgat gaagcagaat gcgctttcga
     4561 gcttactact gcctgagcta agcggacctt ggcttactct gcaaatggca gcccgtagct
     4621 ttgtgccaag aaaggcgggt cgtttcattc gtaatctccg tgaggcttgg ttgcgcaaac
     4681 ctgatacaaa actctcgctt catcatgatg ctacagaggc agaaatacct gtgggtttta
     4741 ctgatgaaga aaaagtgaac tatgctcgcc aagcattaaa aatgatgggg ttaacagaga
     4801 acatcgcacc cttggtcgtg atctgcgggc atggcagtca aagtactaat aatccttatt
     4861 ccgcagccct tgattgtggt gcctgcggtg gagcggccgg tggattcaat gctagagttt
     4921 tagctgcttt atgtaatcta tcagaggtac gagaagctct tttagctgaa ggaattcaaa
     4981 ttcctgagga tacggttttt gcagcagccg aacataatac aacagtagat gaattacatt
     5041 ggctttatgt accagagctt tccgaagctg cacaagaagc atttgaacaa attgaagctg
     5101 ttatgccgaa agtgagacat catgtaaacg cagaacgtct ggaccaatta ccgaatttcc
     5161 aatcgaagct aaaaaatccg aaggctgagg caaaccgatt tgcggaggat tggagtgaga
     5221 tacgtccgga atggggactg gctcgtaatg ccgcttttat tatcggtaaa cgtgaactaa
     5281 ctcaggattg tgatttggaa ggcagagcct ttctccataa ttatgattgg aagcaggatg
     5341 aaagcggtga actcctagca aatattattg caggacctgg tactgtagcc caatggatta
     5401 atttacaata ttacgcatca acggtagcac ctcattatta tggcagcgga aataaagcaa
     5461 ctcaaaccgt tactgcaggt ctcggcgtta tgcaggggaa tgcaagcgac ttgttagccg
     5521 gactgccttg gcaatccgtc atggaatcag atcacgaggc ctatcattct cctcttcgtt
     5581 tattgatact catccaagca cctagagaat atgtggaacg gttattaaat catgactcag
     5641 catttctgca aaaagttcaa aatggatggg tccgactggc tagtattgat ccagaaggat
     5701 gttgggaaag ctggtaatga tgaatctaag catttatcaa atggatttgt tactcaatac
     5761 aaaaatgata aacataagga agaggtgtgc tgtatgaatg taaaccaaaa taaaaaagta
     5821 ttatttttga cggatattga aaacggtttg gagcctattt tacaagaagc gactaacact
     5881 tctgcagaga atatgttgac tatacaaagc tatggtgccg gtatctcaca tccttatgga
     5941 gaaatcatga ggtctgttat ttttgcgatt taccaggagg atgttgagga gatttttgta
     6001 gtaggaacaa aagataagaa gacttccgca ggtaatggac taactcaact tgaaacaatg
     6061 aaagataaaa tacaaacatt ggattatctc tttcaaaatt gcaagcctga atttttaggt
     6121 ggtacggtcg atgaatggct aaatgaaaat agcagtgaca ccattgaaaa aagtgttgat
     6181 atgattcgac gtcatcccct agtgccgtca tatgttaaag ttcgaggttt actcgttaat
     6241 cataaggatg gaagaccctc aattgtggag gatcctgcta ttaaaacagg tcaagccata
     6301 cctgatcatt gcttgtcatg aaaatgcagg ttcaacttct aaacgcacct atatatggag
     6361 aaagcagttc taaggagatt gtatgagcgc taatttaact gattttgtca cgaaaacaat
     6421 agaggacatg aactcgtttg atcgtgaaaa tatggaatgt atgaaaaaac taattagaaa
     6481 agcaattgat ttttatcatc taaagtctta tgaagaagtt gaggaaaccc attcaggaaa
     6541 cgttcgattt ttgcatgtcc actctatgat ggaagaaaat atgttatcca aaatgatagt
     6601 ggtcacaaga aacggtaaaa ctgatttgga tattgaaggt gtatatgaag gatatgttgt
     6661 aagagaatat taatgagacg aaaccacaaa tagaatatgc aatttttttg ctcaggagat
     6721 gtattagata tgaaaaaatc gaagggttct attgaatcag agatcagtaa gtccattact
     6781 caatgggaga aggattatct tgggcggggg tctgtatctg ttaagactga tatactgcgg
     6841 gacatgatca tcgtcaattt aaaagggatt ttaacaccag ccgaatatgt agtttgtggg
     6901 tcaaaagagg gtatgttatc tatcaaacaa actcgttcag aattagtcga atcaggtata
     6961 gaaggcctta aggatattat cttaaaaata accggagaaa aagtgaaaag ttttcatact
     7021 gatttaagct cccggacagg tgaacgagtg atggtgttta aattatgtaa tgatctagag
     7081 aaaaatcttt aatgtaaatg ttttatgatc actgatattc aagccagcag agggctgaag
     7141 gcattctggt tattcataag ttgtaatatt ttttattcat aacctaagcg gacataaaga
     7201 gatgtcaatt catagtacac tgacttgtta ttcctgtcga aagatctaac atccgctgtt
     7261 gttatgagcg gatgtttttt acatctaaat ttgctgctgg tgattagtca cttgaacaat
     7321 accaaattca ttttaattga aaacatcctt gtcacctgct gggttcctcc aagtgtttag
     7381 tgacatgatt atgagaccaa tttcgtaaag cttgctgata aatttaagcg gtgaacaaaa
     7441 ttgatatgct gtcttcagtt tcatttcacg gaattagtca gagataaacc tttaattaaa
     7501 tatatccaaa aaacggattg acatatcgaa atataacgat ataataatcg atatggaacc
     7561 aattgaagta ttcaaagcct tatcaaatga atcaaggctg caaattttac aatggctgaa
     7621 ggagcccgat cgtcattttg caccccatga agggattgat atgaacacaa tcggggtatg
     7681 tgtcagtcaa ataacagaca aattgaaaat gacgcaatcg acagcttctc aatatcttac
     7741 catcctttta agagccggct tgattaaggc ggagcgtatt ggaaagtaca catattacaa
     7801 aagagatgaa gaagccattg ggaaacttgc tgactttctt aaaacagaga tataaaaata
     7861 aacatcaaaa gatgtttatt tttacaccat acatatcgac atattacgat gtgtttattt
     7921 tttataataa catatcgata attcgtgata tgtttattaa taattaagga gtgaatgttt
     7981 tatgtctaac acttggaaaa tttatatttt agccattgtc agctttttag ttggaacctc
     8041 agagtacatc atttccggaa ttttggatca aattgctcat actctcggga tcactttagc
     8101 tgccgcgggc cagcttatta ccattttctc acttgtatat gctctttcta cacccgtact
     8161 tatggcgtta acagcaagta tggatagacg caaattgatg atgtatgccc taggtttgtt
     8221 tgtgttcggt aatgtcctgg cttttgtact gcctggttat ggatggttta ttgcagcgcg
     8281 gatcattatg gcgatgggag caggtgtggt ggttgtcacc gccttaacga ttgccgctaa
     8341 aattgcatcg gaagggaagc agggaagtgc catcgctacg gtcgtgatgg gatttaccgc
     8401 ttctttaatc ataggtgttc cgcttggaag aatgatagca gtagcattag gctggaagtc
     8461 tgtatttgga gcaattgctt tgttgggatt gatcgcaatg gtcgttattt tctttactct
     8521 tccgcatact gaaggggata agcctgtgcc tttgcttcaa cagcttgctc ttttcaaaaa
     8581 acggaaagtg gctatgggat tatcaatcac tttcttctgg ctcgggggat attctgttgc
     8641 ttacacttat ttgtcaccgt atctcttgaa catctcaggt ataaatggca agctgctcag
     8701 tggtgttttg cttatatttg gaattgccag tttggttgga tcaaagtttg ggggatatag
     8761 caccgataaa tggggagtgt cctttacact cgttggcggg atgacgttgc atatcgtcac
     8821 actgattctt ctgtcacttg ttactcattc ctatatcgga gtgttggtga ttctcatatt
     8881 atggtcgttt gccgcatggt ctaccggtcc gacacagcaa tttcacctgg ctacaataga
     8941 accggaaatg tcaggtgttt tgcttagcat gaatcagtca atgatgcaat tcgccatggc
     9001 ggtcggcgca ggtataggag gggtttttgt ggaaaacgta tcattgacct cgattacctg
     9061 ggttggtgcg ttaggggtta tgattgcaat tattacatca ttgacgattt ttcattcaca
     9121 accgaaacag acgttaaaag atatcaatca ataatttcga aagatctaac atccgctcgt
     9181 tatacaagcg ggtgtttttt ataagcgttc aaagtcagtc catgtatgag ccttccaagg
     9241 gccgacatcg ttctgtatgt gtcgagggcg cactgaagct gaaagggatt tcttaaggct
     9301 ttgccgctga agtacggtac gattgccttg atcgaacact ggaaacacaa gagaacgtaa
     9361 acctgaacat ccgcgtaaac gtcaaggaag ttgccacttg gggagtaaac acttgcatca
     9421 tctcgctgaa aggcctagac aatgcggatg acatattcgt attgccggaa gtaaacacag
     9481 cgcttgctct gtttccgttg gtttctgttg tcggttgcag ctgattgctt actaatgctg
     9541 ccctgcatct cggttgtgat gtcgataagc agcgtaacct tatgaagagt gttactgtag
     9601 acttcattca tttaactaaa gtcattgctt tcttaatcac taaagtttat ttgaaaataa
     9661 tctcttgatt taatttcctc gaagagattg tttgtcaatc tattaggcat cagaattttt
     9721 ataacagaat ggatcgtctt tttgacgttt tgtttataga acaagaaaat attcaaaaca
     9781 taagtggaaa attaggggtg agctcctgtt tttctcgaga ggatagcttg tcagcttttc
     9841 tatttttaaa gggttaaaat attctattta tactaattaa tgtaattttt aggataatat
     9901 acaaaatccc ccttacttcg acaattgcaa tctggtatta tcgtatcgca tgggagctat
     9961 gtcaatagac tctatgcaaa aattgagagg aggtttactt atgaaaagaa accaaaaaga
    10021 atgggaatct gttagtaaaa aaggacttat gaagccggga ggtacttcga ttgtgaaggc
    10081 tgctggctgc atgggctgtt gggcctcgaa gagtattgct atgacacgtg tttgtgcact
    10141 tccgcatcct gctatgagag ctatttaaca tttgagaata gggagttgag cgtatttgct
    10201 tatactcctt attttctctt aagggggatt ttatatgtca tatgatcgtg ttaaagattt
    10261 tgatttgcca gagttagcgg ttcatttaca gcctcatggt gctgtaatga ttgatagaaa
    10321 aagtatgttt tatttcagac tcagtggacg tggagcacag ttggcgtttc tgttatcaaa
    10381 aaacaaaaac cttcataaaa cggcacgtat ttgggagatt atgaaaaaag aagagatgag
    10441 tgctgaccaa ttaaaagaag agcttagtgc ccatccattt acggaggctt ggacggaagg
    10501 gctgttagat cagcctttac acgtttcggg ttcgctagat tcatatttac ctattagttg
    10561 taccttgcag ttgacaaatg cttgtaattt aagctgttcg ttttgctatg ccagctcagg
    10621 taaaccatat cctgaggaac tatctagtga acaatggata ttggttatgc aaaagttagc
    10681 agcccatgga gttgctgata ttacgctgac cgggggtgaa gcaaagctga tcaaagggtt
    10741 taaagaatta gtcgttgttg caagttcgtt gtttaccaat gtgaatgtat ttagtaatgg
    10801 attgaactgg cgagatgaag aagttgaatt acttagtcac ttaggcaatg tttctgtaca
    10861 gattagtatt gatggtatgg ataatacaca tgaccaatta agaggcagaa aaggcggctt
    10921 taaagaaagt atgaatacca ttaaaaaatt atcagaagca aacattccag tgattgtcgc
    10981 tatgaccatt aatgagtcca atgctgatga agtatcagat gtggtggagc aatgtgccaa
    11041 tgcgggtgct tttatctttc gtgcaggaaa aacgttatct gttggacgtg cgtcagaagg
    11101 ctttaaggct ttggatattg attttgaaga aatggttcaa atacagctta gggaagcacg
    11161 tcataaatgg ggagatcgcc tgaacataat tgattgggag cacgaagaga gttcgttcac
    11221 aacagatttt tgtacaccag gatatcttgc ttggtatata agagcagatg gatacgtaac
    11281 tccttgccaa ttagaagatt tgccgctagg gcatatttta gaagatagca tggctgacat
    11341 tggttcacct gctcgtttgc ttcagttaaa atgtgaagct aaaaattgca aatgtatagg
    11401 gaaaattgag ctatctgaac cggacttgcc ttttcaaaaa gaattcaagg cagggattca
    11461 ggaatgaata gtctatcatt ggtgttctgg agtattttag cagttgttgg attactgtta
    11521 tttattaaat tcaaaccccc aacaattgct tcactactct taagcaaaga tgaggcaaaa
    11581 gaaataagca ttcaatttat aaaagagttt gttgggatag atgtagagaa ctgggatttt
    11641 tattcggtat attggtatga ccacgataca gtaaataaac ttcatcactt aggcatactt
    11701 aagaaaaata gaaaggtttt atatgatgtt gggttggtcg aatcatggag agtccgtttc
    11761 gttcaccaga atcaatcatt tgtagttggt gtcaatgcca atcgagaaat cacttttttt
    11821 tatgcggatg ttccgaaaaa aaccctttcg gggaagtttg aacaagtttc tccagagaca
    11881 ctcaagcaga ggttaatggc ttcacctgat ggactttggt ctagagcaaa tatgactggt
    11941 actggtaaaa aagaggagga ttttcgcgag gtcagtactt attggtacat agcggaagcg
    12001 ggagatattc ggctcaaggt gactgttgaa ttacagggcg gccgaatttc ttatgttggt
    12061 actgaacaag aaatactaac agatcaaatg agtaaagtca ttcgagatga acaagtggaa
    12121 tcgacattcg gagtatctgg tatgctgggt tcagctttag cgatgatcct tgcgattctc
    12181 atccttgtat ttatggatgt gcaaacaagc ataatcttca gtcttgttct gggtttgttg
    12241 attataatat gccagtcatt gacgctgaaa gaagatattc aattaacaat tgtaaatgct
    12301 tatgatgcaa gaatgagtgt caaaacggtc agtttattag gtattttgtc tacacttctt
    12361 acaggattat taacaggatt tgtagtattt atatgttcat tggcaggaaa tgcgcttgct
    12421 ggtgattttg gatggaaaac gtttgaacaa ccaatagttc agattttcta tggaatagga
    12481 gcagggctca ttagtttagg agtgacttct ctgctgttta acttattgga gaaaaagcat
    12541 tatttacgaa tttcacctga gctttctaac cgaactgtct ttctatcagg ttttaccttt
    12601 aggcaaggat tgaatatgag catacaaagt tcaattggag aagaggtcat ctatcggcta
    12661 ttaatgattc cagtcatttg gtggatgagt ggaaatatcc tcatctccat tattgtatct
    12721 tcctttttat gggcggtgat gcaccaagta actggatatg acccaaggtg gatacgttgg
    12781 ctgcatctat ttatattcgg ttgctttctg ggagttctct tcatcaaatt tggttttatt
    12841 tgtgtattag tagctcattt cattcataat ttagtactcg tctgtatgcc gctgtggcag
    12901 ttcaagcttc agaaacatat gcatcatgat cagccaaagc atacttcact ctaatgatta
    12961 ggagaagatt tgatgcaatt gatgcaagtg caaaatttaa gcaaatgcta tcgaaatggt
    13021 gatggggttg aacatttgtc tttctcaatt caacgaggag aaatcgtggc gctattgggg
    13081 ccaaatggag ctggaaaaac aacgacaatt cgatgtttga caggtctcta taagccggat
    13141 aaaggagata tcctcattga gggttctcct ccaggacata taaatgttca aaaaaaagtc
    13201 gcgcttattc ctgatcagcc atatctgtat cccgctttaa ccgctgctga acatattcag
    13261 tttagggcaa gaggatatca tccaggtaaa aaagatgtaa aagaaagggt ttatcatgca
    13321 ttgaaggaag tgcacttgga ggagaaagca aaccaattgt gtggtcagct gtcaagaggc
    13381 caaaagcagc gggttgtcct ggcgggggcg attgttcaag acgctttgct gtatatatta
    13441 gacgaaccga ctgtgggcct tgatatccca tcaaaacagt ggctctctaa ctggttaaaa
    13501 actaaaaccg atcaagggtg ttcagcattt gtatcaactc atagtctaga gtttgttata
    13561 gagacagcag acagggtgat attaattaga gacggcaaac tcatgcagga tttgtatgtt
    13621 cctcaattcg aagaagaaca agcggaatgg agaaaagaag tgattcgtct tctaggagaa
    13681 tggtcagatg aataatatca tttctttttt atggcttcag tcaaaaaggc gttttgtcag
    13741 tcaaggtcag gaaaaaaaaa tgcctttttt gatcatgctc ctttttgttg gggccatcgg
    13801 atttcaagta agttttgttt ctagatctac gacatgggat atgagtattg ctggttgggt
    13861 acttacaggt gtttttatcc tttatacggc atttggactt ttttcaaatc gattaccaag
    13921 tcaaatggca gatattatat ggctttatgg cactgccaca tctttttcaa aagttgtgta
    13981 tagtgtttta ttttttagcg tcacttggaa ggcgttgctt tggatcatct cagccatatt
    14041 cggtgatgta ttaattgtgc ttctgtctgg tgagcatatc aatttattag gccgatccat
    14101 aatttttgta gggctctttt ttatcgctga agtgtggttg atgtcggtct cttgtgccag
    14161 aacagtgaag aaaatgaaaa gggtatacgt tttagtcttt cttctaatgt taggcattta
    14221 ctccatatgt ctttatcact tcttctttct ccaacattca tctgggatat gggagagcat
    14281 tgcccgtttt attagtggcg ttggattagt gtttgataca ttgtcaccgt tgtatgtggt
    14341 tgtatttatt gggatcatca cagtctcttt tatgacaatt gcttttacga gccgtcaggt
    14401 agaaatgaag gaatcgttgg tgaaagaagc tgaattctgg gaggaatttc aagaacgtca
    14461 atttggttca ggtcaaatta tacagaaacc aaaaacgact tggtggggct tgcaaggtct
    14521 aaatggcatt tggtcttttc tgtggttgga actgttgctt tttaaaaaat atttattttt
    14581 tcatagcatt catacggtca tgctcagtgg cgtcttttat gtcgtcattt tcatgtatcc
    14641 agaatggttt tatcttcttt tctttcttat cgtctcggca gtcatgttaa gttcctatta
    14701 ttcaggaatt gtcagacatt ctcaatcagg cacccttcat ttattccccg gtgccctttg
    14761 gaaaaaaatc attattctag agctgacgaa tacagtctgg ttgtatattc tttactgtgt
    14821 ctctattact tttatggcag ttgggaattt agtttattgg tatatatatg gcttagggat
    14881 atatatatgg ttcatgacaa taaggctttt tgcttttacc catacaaacc gaaacgatat
    14941 taagctttca ttgcctcaat actacaagtc attttttatg gcattaggcc tgagcggcat
    15001 ttgtttgtat gtcattcatt tattgactgc tgactggtat acattagtgg tggtcgtctg
    15061 tatagggagt ctaagttggt gcctgtttta tcgtttcaga tagtggttat gtagagttat
    15121 tgttttaaaa cgaggagagg ggctctttta tgaattcaaa tggtgataaa ttgtcgttat
    15181 ctgttcagaa tttagcgaat acaaatgaga tcacaattgt tcaagcgata ggtgagctaa
    15241 agaaatcggg aaaagatgca ataccagttt tggttgaggc cttaaaagag gaaggctctt
    15301 tgtgtaatat tgctgcagct gttttaggtg agtttgggga agacgcgagt gaagcagcgg
    15361 aggagctatc atgtttatta aaaagtcatg ccgaagatac aagaatggca gcggcgattt
    15421 cattaatgag aatcgggaag cccagtctgc cctttgtcat caaaatcgct caagaaagtg
    15481 aagggcaatc gtgcttttgg gcatcttggt gtattgcatg gattgatccg tcttgcattg
    15541 aacctaagat gtataaatgt ctaaaatacg agcatgaaca tccttcagga atagttgctc
    15601 cgtttgcggc tgaagaggca ttaggaaagc tgattgcttt tcagctgaaa gataaggagg
    15661 actgaaagga tgaaagatga acaaatgttg actgaatggc caagtcattt accatggttg
    15721 aatcaatcac agaatgattt tacatttcca agtgacacat atcttcttct ttatttttgg
    15781 tcaatgagct gtccaaactg tcaccaatta acagacaaag tccttcaaga tataaaggat
    15841 atgaatgtga aagtaatcgg agtacatgtc ccctatatag aagaagagaa atctatggag
    15901 gttgtcttga cgtatgctct tgatagggga ctagctattc cgattgtatt agaccaaaac
    15961 tatgagatcg tcacaacttg tcacgtacaa ggcatcccca gcttttgtct attaagccaa
    16021 tacggtcaga tcattactaa aacgatggga gatgttggtt gggataagat gttaaaaaag
    16081 attgcaggct tgtgaaattt tccgtcttgt atgtgcgaca aacggttgaa tattatgatg
    16141 aaacggtcct tcctataagc aggaaggttt tttaatgaaa tattttttta ttagtaggta
    16201 aattcatcaa atgttctgct atgctccaaa tgtacacctt tccgtaaggg caaagttaaa
    16261 tgtgaaaata aaactgttcc aaagttaatc agaaatttat tttcatattg tatcctttcg
    16321 gtatcaagtg aaaggagcat catatgaaaa cattatggaa agtcctaaaa attgtttttg
    16381 tcagcttggc tgctttggtt ttgcttgtat ccgtctcggt atttatttat caccatttcc
    16441 agctaaataa ggaggcggca ctgctgaaag gtaaaggcac attagtcgat gttgacggta
    16501 aaaagatgaa tgtgtatcaa gagggaagcg ggaaggatac gtttgtgttt atgtccggtt
    16561 cggggattgc tgcgcctgct tatgaaatga aggggctgta cagcaagttt tcaaaagaaa
    16621 ataagattgc tgttgtagat cgggcaggtt atggatacag tgaagtgtct cacgatgaca
    16681 gagatattga tacggtattg gaacagacga ggaaagcgct tatgaaaagc ggaaataagc
    16741 ctccttatat tttaatgcct cattcgatat ccgggattga agcgatgtat tgggcacaga
    16801 aatatcctaa ggaaatcaag gccattattg cgatggatat tggattgccc cagcagtacg
    16861 tcacgtataa attgagcgga gttgacagat tgaaagtgag agggttccac ctgttaacct
    16921 cgattggctt tcatcggttt atgccttccg ctgtatataa tcctgaggcg attcggcagt
    16981 cgtttttaac tgatgaagaa aaagaaatct ataaagccat taactttaag cagtttttta
    17041 atgcagatat ggagcatgag cttttacaat cttaccaaaa cggcagcaaa tctgtgaatc
    17101 tgccggcacc aaaggaaact cccgtcttga ttttagatgc ggtctctgac caaaatagac
    17161 attcaaagta tgctatacaa aaccgaaaag attatgaagc gtttgcggct caattcaata
    17221 ctgccgatat aaaggaactg aggggaacac acagtattta tttatatcag cctgatcaaa
    17281 tatataaact gtccatggag tttatgagaa aggttcgcta ggatgaaggg ttatcatatt
    17341 ttaatcgttg aagacgatgt gatgattggt gatttgctgc aaaagatttt gcagcgtgag
    17401 ggatatcgtg tgatatggaa aacagatgga gcggatgtgc tttcggtgat tcagaaggtg
    17461 gatttggtca ttatggatgt gatgctgccg ggtgaagacg ggtatcaaat gtctgcaaaa
    17521 atcaaagagc tggggctggg cattccggtt atttttcttt cggcccgtaa tgatatggac
    17581 agcaagcttc aaggtttgca gatcggcgag gattatatgg taaagccctt tgatccgaga
    17641 gagctgctat taagattgcg gaatatgctt gagcatcatt atggcacctt tacgcaaatc
    17701 aaacatttgt atattgatgc ggtaacgaaa aaagtgttca atgaaagcct gcatgatgag
    17761 gtattgttta ctgcgattga gcggaaaatt ttcttttatt tatatgaaaa tagagacagt
    17821 atcctgacaa aggaacattt ctttgaatat ctatggcagc tcgaagatag aaacccgaat
    17881 attgtcaatg tgcatattaa aaaaatcaga gctaaaatca atgatcaagc gggtgagatg
    17941 attgaaaata tatatggaga agggtatcgg ctgaataccg ttgtgaagaa atgaagctca
    18001 agacaaaata tcagttgtta ttgtttacgg cggtcattag tgttccggtg ctattgctgg
    18061 cggtcagtgt tttgatgtcg gtgatttatg acagcatgtt taaaacgatg aatcatggta
    18121 tgccctttca caggtcgttt gcgtacccgg caatgatcgt tgtatttttg atatcgctct
    18181 tattgttagc ttttttattt tcaaagtcga ttcattctct gttgcataaa atcaatctat
    18241 taaatcaaac cattcggcat ttggcgagtg atcaaagggt gcccgataaa attgaagtga
    18301 agcgtgcgga tgaaatcgga gaactgatca agtcggtcaa tttgttaatt gaacggacga
    18361 catatcgtga actggagctg agacagcagg aggaaatcaa aaaggagctt ttgcaaaaac
    18421 tgcggcatga cattaataca cctttaacgg ctctcaggct gcagttattt tatttggaag
    18481 accaatgtca tggtcaggct gtattcgaat cattgtatca gcaaatcgaa tatatctcgg
    18541 aattaaccaa tgaattcaat ctatattccg ctgagacgct ggaaagctct tatattgtaa
    18601 atgaagaagt gcgtctaaac gagctattag aaacagcggt gaaaaagtgg gattatttat
    18661 acagtatgag tgggattgag ctgcactata agccggcaga tcaagatgtg atatggatga
    18721 gcaacgcgtt atggatgcaa aggctgtttg ataatatttt tcaaaatacg ttaaagcatt
    18781 caaaagctga aaagatggaa gtcacgattg aacatggcga tgtttttatt cgtgatgacg
    18841 gtattggatt tgatcggaat gagagcagtg agggacttgg gttaaagatt attgaggata
    18901 catgcaggct gcttgcgatt acttatgagc tgcatacaaa tgataacgga acggggttct
    18961 tgttttcaaa agagtgaccc cgctgatgtt tttctttctc ctataaaatt tatataatag
    19021 gagaaagaaa tggggtcaac agcatatgtt taaaaaaatc atcaaaacga ttaagtacct
    19081 ctcaagcagt tctagtgacc gatatcgcag acaccggcat tacagcagca gtcggcgcag
    19141 acattatcgc agctacagca gcagttcggg caaaagaaga cactacgacc gttatggcgg
    19201 cagtcatcgt tacaaacgcc ggagctacag cagcagttaa tccaaaaaaa gttcttgttc
    19261 cgcttttggg acaagggttt ttttatgtga ccgattgaat ggcccagttt agatcctcgc
    19321 gaatggaagc ggtgtgctga tactcttcct caatgcccaa taatcttttc agcagcaagg
    19381 ttacttcctt tgtcagtgtt aattcctcca gccaagtgcc gtttttcttc ttttttcctt
    19441 tatattgaga gtacagcagg aataacagcg tttctccgag atcgaagaag tcatcctgtt
    19501 ttcgtacctt tatttcctcc atttcttcag gagtcaattg tttggcaagg ccgaaatcga
    19561 tgaggcagag cctgccgtca ttgatgatga tattaggcgt tctgatgtcg ctgtggaaga
    19621 taaggcgatc atgcaggtat tctataatct caagcagctg cgaaatcagt tgtaatgcca
    19681 taagctctgt gaacggctgt tttcgaaaaa ataataattc ttctatattc tctccctcaa
    19741 tgaactgcat gacataataa gcctgtccgt ctatgatgaa ctcatctatg aagcccggaa
    19801 tttgcgggtg gtgaatgctt ttgagaagtt ttatttcctg ctggaaccgg actttttctt
    19861 tttccttttt cgcttttgtc ggccgaagct gttttaagac ataaggtgtt tgagttagga
    19921 tatcggtgca caaataaacc aaaccgtagc ctcccatacc gaggcactct tcgattttgt
    19981 attgatgatt taagataacg ccgttcttta gagggcggtc aaatagcagt ttttttagaa
    20041 gttttaatgc catgtctgca cttcccttgg ttgtactgac tatagtttac cttctagact
    20101 gagaataaaa aagagccgga taaccggctc ggtataagtt aaaactgctt tgtcacgtcg
    20161 tattcataat ctatttttgc ttttacgttg ctcatcgtcg atctggctgt cgctaatgta
    20221 ttatatttaa aactccatac ctttgccaca ctgagttgat ctgacaaaga gatatcataa
    20281 gaccctgaag tcgagctgtt tacaagagca cggcgccatt cgttgttttc gctcgtcatg
    20341 atcaggtggc gtgtatttcc ctggcttggt gtttgagtgg cggttgtctg aactctggtt
    20401 acaatggcat cacgcggtat cccagattgg tttgttaaat caaccttgat cacgctggag
    20461 tcagaacctg aggggctaag gcttgtattt cctttatttt cagcaacgcc gctgaattgg
    20521 aacgttccgc tgcctgattt gattcggtct tcaattgaaa gtgtaaaata catgtttccg
    20581 gtataggtgc ctcgtgacac tttcacataa aaggtatctg tcgtgttttg ggcgtctgca
    20641 tttgcataaa taaaagaaga aaacgtatta gggttaatga cttctgtccc ttgagaaaca
    20701 ggtattctat tcttatcata aatttcaatt ttcatccctg tatacgcgct ctggtatgta
    20761 ctcctcacgt atactttttc tcccttatta gctgtaaaag tgaaataggc ttcatcttga
    20821 ccagcttcca gtattgttgt atcgatattt ttatatttcc aataaccgat cggcattgcg
    20881 gtatcaaatg aattgtttcc tgtgatagca gtgactccga cagctgatgc cgaatacgta
    20941 aaggtgaata agacagacag cataacagcg aatggaataa gccatttttt caccatgcaa
    21001 acaacctcct tttatttcca tcatacataa taacgattta ggtgtaaata aatgtttttt
    21061 gaggttaata tatacattat ctttgccgat aaaaaagaat aagagagaat actcgggagg
    21121 gaattcaatg cgtctgaatc ggcaatttat ccgcactcag ctgatggcac agaacatatt
    21181 gagcaagaat gcgcctgcca aacgggagaa tgcgactgaa aatccagcag cagttctgga
    21241 aaaggcatac agcaggctta agtcacaatc ttcaactggg ggaatcaatc agttcaatta
    21301 ttctaaaacc ggcgtgtcgg gaaacagcgg gacgttcagc aaagtgtatc aatcagcgaa
    21361 tgatcgaaca gtgacagaca caggggaaga aacagtgatt caatcccaaa acccctatga
    21421 atctgagagt gatatcagaa tcaaaatact agatgaaaaa tacagcagga tgaatgcgat
    21481 taataaaaca aagtctgatc cattaggcta tattaaggat aagtaccaaa attcaaagtc
    21541 tccttatttc agaagtgatc tgtcagctgc agaaagacag gccgcttacg ataatgaaac
    21601 agaatggtta ttcaaaggga aggcgcaaaa ctataacctt caggatgctg cgtttcggaa
    21661 tgtcacattt catggggaag tggaagctga gaatgaaaag gtgtatcagc ggggacaggt
    21721 taaccagcag ctacaagtgc tgttgaatcg aaaccatatt catattccag aggggacaga
    21781 gctgacgttt acgattacgc cgattgacta tcaggtgcgg gtgagcggga cagacgatca
    21841 ggatctgatc aagcaaattg agcaagtgct gcaatctgga gacaacagca aagagctatt
    21901 tttgcatatc atgaaaagcc agagtcctga ttcagcacaa ttttctgaag aggcatatca
    21961 aaagtatcag gctgctcgtg agatgtatga agttacaggc taccatttga aggatttgga
    22021 agtgattgac gggcggtacg tcacgcctga tggacgtgac ttaatagatg tatataagga
    22081 agagcttgaa aaagatccag tgcagaagca aacggcttct tatgctatat cttactatcg
    22141 ttcagagctc agtaaaatcg cggaagccgg gtataatgcc attccggatt tcatcctatc
    22201 aattgattac agcaatggat ctctgagaga tgtgggacaa agcaagagct atgggaccgg
    22261 agataccggg tggcttgaag cattaaagcg tcaaacgggt gtgaattatt aggtaagctg
    22321 ttcatgtaga acagcttatt ttttatgaga atctaagggg tgtattaatt tcaatattca
    22381 aataatttta ttatttttat ataaaagatt ttaaaagaag tgaacgattc aaaactctga
    22441 acaaaggtgt ttacctgaaa aaaacaattg tattttccag agaaatttat tatgatgaaa
    22501 taagtaattt aggagattat ataacaattt taagtttgaa ttttctgatt gttatcactg
    22561 attcatgtga aggcaagcag gtctgctgtt ttctcattta tgagtatttt gttaggagga
    22621 ggaagaggag tggcaaataa agaattaaag aggggcctgg gcgcgcgcca tattcagatg
    22681 atcgccttgg gcggtacaat cggtgttggc ttgtttatgg gttctgccag cacgatttca
    22741 tggactggcc catctgtcct tctggcttat gcaatatgcg gaatttttat cttttttatt
    22801 atgcgtgcga tgggtgaaat gctgtatgtc gagccgagca caggctcttt tgcgacgttc
    22861 ggccatcaat atattcatcc gatggcaggt tatataacag catggagcaa ctggttccag
    22921 tggattatcg tcggcatgtc agaaattatc gctg
//
