LOCUS       NZ_JALAVI010000026      9421 bp    DNA     linear   CON 26-JAN-2024
DEFINITION  Bacillus inaquosorum strain EC30O4B-A7 contig_0000026, whole genome
            shotgun sequence.
ACCESSION   NZ_JALAVI010000026
VERSION     NZ_JALAVI010000026.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus inaquosorum
  ORGANISM  Bacillus inaquosorum
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 9421)
  AUTHORS   Dunlap,C.
  TITLE     Crop Bioprotection Bacillus Genome Sequencing
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9421)
  AUTHORS   Dunlap,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-FEB-2022) CBP, USDA-ARS-NCAUR, 1815 N. University St.,
            Peoria, IL 61604, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC NGS Cell v. 21
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 168.96085678627867x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/24/2024 02:36:42
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,244
            CDSs (total)                      :: 4,173
            Genes (coding)                    :: 4,038
            CDSs (with protein)               :: 4,038
            Genes (RNA)                       :: 71
            rRNAs                             :: 4, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 3 (5S)
            tRNAs                             :: 60
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 86 of 135
            Pseudo Genes (incomplete)         :: 70 of 135
            Pseudo Genes (internal stop)      :: 30 of 135
            Pseudo Genes (multiple problems)  :: 40 of 135
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:28:30
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 9421
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JALAVI010000026.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     gene            <1..3673
                     /locus_tag="MOE80_RS21175"
                     /old_locus_tag="MOE80_21115"
     source          1..9421
                     /db_xref="taxon:483913"
                     /mol_type="genomic DNA"
                     /organism="Bacillus inaquosorum"
                     /strain="EC30O4B-A7"
                     /submitter_seqid="contig_0000026"
     region          1..9421
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..9421
                     /SMILES="NC([*])C(=O)N1C(CCC1)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..9421
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<2:>9421](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      <3..>9421
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     CDS             <3..3673
                     /NRPS_PKS="Domain: AMP-binding (178-571). E-value: 3e-115.
                     Score: 377.0. Matches aSDomain:
                     nrpspksdomains_MOE80_RS21175_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (676-744). E-value: 1.1e-24. Score:
                     78.4. Matches aSDomain: nrpspksdomains_MOE80_RS21175_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (754-1056). E-value:
                     8.9e-167. Score: 548.1. Matches aSDomain:
                     nrpspksdomains_MOE80_RS21175_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (1062-1216). E-value: 1.3e-52.
                     Score: 169.7. Matches aSDomain:
                     nrpspksdomains_MOE80_RS21175_TIGR01720.1"
                     /codon_start=2
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389714.1"
                     /locus_tag="MOE80_RS21175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE80_21115"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_268399817.1"
                     /sec_met_domain="AMP-binding (E-value: 6.8e-124, bitscore:
                     400.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.2e-16, bitscore:
                     48.2, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 1.8e-79, bitscore:
                     254.0, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="FVNTLALRTRPEGGKPFVEYLQEVRDTALGAYEHQDYPFEELVDK
                     LKLTRDMSRNPLFDVMFVLQNMDQESIQLEELHLKPAANNGHQTSKFDLTLYAHEQPCG
                     LLTFQMEFSTDLYKKKTIEKWLQYFINMLLSITQDNKAALGTINILNEDETHYLIHELN
                     RTKIDYPRNETISRLFEMQAEQTPNAIAIVSDTQELTYADLNSRANQIASVLQRKGVGP
                     DRVVALLTGRTPELIAGMLGILKAGGAYLPIAPDLPVERIAYMLSDSGATLLLRSEKAE
                     KRQLDIACEQFIIEDIQKQGETKNIESSAGPHSLAYIIYTSGSTGKPKGVMIEQRSVIR
                     LVKNSNYITFTPADRLLMTSSIGFDVVTFEIFGPLLNGAALHLSDKEVFLDSYQLQRYI
                     EHHGITTMWLTSSLFNHLTEQNETTFSQLNHLIIGGEALSASHVNRIRNVCPEVSIWNG
                     YGPTENTTFSTCFHIQKTYELSIPIGRPVGNSTTYILNKWGMLQPIGAVGELCVGGDGV
                     ARGYLGRPDLTKEKFVPNPFAPGDRLYRTGDLARWLPDGTIEYVGRIDDQVKVRGYRVE
                     LGEIESALRQIDGVKEAAVLARTGQTGSKELFGYISVNAGTNAEQVRSLLARSLPNYMI
                     PAYIIEMETLPLTSNGKLNRKALPEPDFASKQTYVPPRDDLEEQLALIWQEVLGIQRIG
                     IEDSFFELGGDSIKALQVSARLGRHGLSLQVSDLFRHPKIKDLSPFIRKTERIIEQGPI
                     QGDVPWTPVQQWFLSQDIEERHHFNQSVMLFHSDRLSEDALRAALKKLAEHHDALRMVY
                     RNDDGRWIQINQGIQESQLYSLRISDLSQSESGWETQIKQEVADLQQSINLQEGPLLHA
                     AWFKTLTGDYLFLAIHHLVVDGVAWRILLEDLSAGYQQASSGQAIQLPPKTDSYQEYAR
                     RIQEYAQSSRLIREEAYWRTVEEQQAAELPYEMPLHENTDFSRRDSIRFSLSETDTAVL
                     LQNVNHAYGTDTQDILLTAASLAICEWTGGSKLRIAMEGHGREHILPELDISRTVGWFT
                     SMYPALISFENHRDELGTAVKTVKDTLGRIPNKGVGYGMLKYLTHPENKSIAFSKTPDI
                     SFNYLGQFNDIERQDSFRPSSLGSGKDITHTWKREQIIEMSAMAADKKLHFNLSYPPAL
                     FHRNTMEQLINRMEHFLRDIMKHCAGKQKAEKTLSDFSSQSLTAEDLDSISSLVEEL"
     CDS_motif       77..196
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS21175_0001"
                     /evalue="9.40E-24"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="MOE80_RS21175"
                     /protein_end="64"
                     /protein_start="24"
                     /score="75.9"
                     /tool="antismash"
                     /translation="RDTALGAYEHQDYPFEELVDKLKLTRDMSRNPLFDVMFVL"
     aSDomain        539..1717
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE80_RS21175_AMP-binding.1"
                     /evalue="3.00E-115"
                     /label="MOE80_RS21175_AMP-binding.1"
                     /locus_tag="MOE80_RS21175"
                     /protein_end="571"
                     /protein_start="178"
                     /score="377.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FEMQAEQTPNAIAIVSDTQELTYADLNSRANQIASVLQRKGVGPD
                     RVVALLTGRTPELIAGMLGILKAGGAYLPIAPDLPVERIAYMLSDSGATLLLRSEKAEK
                     RQLDIACEQFIIEDIQKQGETKNIESSAGPHSLAYIIYTSGSTGKPKGVMIEQRSVIRL
                     VKNSNYITFTPADRLLMTSSIGFDVVTFEIFGPLLNGAALHLSDKEVFLDSYQLQRYIE
                     HHGITTMWLTSSLFNHLTEQNETTFSQLNHLIIGGEALSASHVNRIRNVCPEVSIWNGY
                     GPTENTTFSTCFHIQKTYELSIPIGRPVGNSTTYILNKWGMLQPIGAVGELCVGGDGVA
                     RGYLGRPDLTKEKFVPNPFAPGDRLYRTGDLARWLPDGTIEYVGRIDDQVKVR"
     aSModule        539..3652
                     /complete
                     /domains="nrpspksdomains_MOE80_RS21175_AMP-binding.1"
                     /domains="nrpspksdomains_MOE80_RS21175_PCP.1"
                     /domains="nrpspksdomains_MOE80_RS21175_Epimerization.1"
                     /domains="nrpspksdomains_MOE80_RS21175_TIGR01720.1"
                     /locus_tags="MOE80_RS21175"
                     /monomer_pairings="X -> D-X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       725..763
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS21175_0002"
                     /evalue="1.60E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="MOE80_RS21175"
                     /protein_end="253"
                     /protein_start="240"
                     /score="15.0"
                     /tool="antismash"
                     /translation="LGILKAGGAYLPI"
     CDS_motif       950..1006
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS21175_0003"
                     /evalue="1.00E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="MOE80_RS21175"
                     /protein_end="334"
                     /protein_start="315"
                     /score="33.3"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGKPKGVMIE"
     CDS_motif       1511..1600
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS21175_0004"
                     /evalue="3.80E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="MOE80_RS21175"
                     /protein_end="532"
                     /protein_start="502"
                     /score="57.5"
                     /tool="antismash"
                     /translation="PIGAVGELCVGGDGVARGYLGRPDLTKEKF"
     CDS_motif       1682..1747
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS21175_0005"
                     /evalue="1.80E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="MOE80_RS21175"
                     /protein_end="581"
                     /protein_start="559"
                     /score="39.1"
                     /tool="antismash"
                     /translation="YVGRIDDQVKVRGYRVELGEIE"
     aSDomain        2033..2236
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE80_RS21175_PCP.1"
                     /evalue="1.10E-24"
                     /label="MOE80_RS21175_PCP.1"
                     /locus_tag="MOE80_RS21175"
                     /protein_end="744"
                     /protein_start="676"
                     /score="78.4"
                     /tool="antismash"
                     /translation="EEQLALIWQEVLGIQRIGIEDSFFELGGDSIKALQVSARLGRHGL
                     SLQVSDLFRHPKIKDLSPFIRKT"
     aSDomain        2267..3172
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE80_RS21175_Epimerization.1"
                     /evalue="8.90E-167"
                     /label="MOE80_RS21175_Epimerization.1"
                     /locus_tag="MOE80_RS21175"
                     /protein_end="1056"
                     /protein_start="754"
                     /score="548.1"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLVVDG"
                     /tool="antismash"
                     /translation="GDVPWTPVQQWFLSQDIEERHHFNQSVMLFHSDRLSEDALRAALK
                     KLAEHHDALRMVYRNDDGRWIQINQGIQESQLYSLRISDLSQSESGWETQIKQEVADLQ
                     QSINLQEGPLLHAAWFKTLTGDYLFLAIHHLVVDGVAWRILLEDLSAGYQQASSGQAIQ
                     LPPKTDSYQEYARRIQEYAQSSRLIREEAYWRTVEEQQAAELPYEMPLHENTDFSRRDS
                     IRFSLSETDTAVLLQNVNHAYGTDTQDILLTAASLAICEWTGGSKLRIAMEGHGREHIL
                     PELDISRTVGWFTSMYPALIS"
     CDS_motif       2366..2443
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS21175_0006"
                     /evalue="1.70E-05"
                     /label="C2_LCL_024-062"
                     /locus_tag="MOE80_RS21175"
                     /protein_end="813"
                     /protein_start="787"
                     /score="17.2"
                     /tool="antismash"
                     /translation="RLSEDALRAALKKLAEHHDALRMVYR"
     CDS_motif       2648..2713
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS21175_0007"
                     /evalue="3.10E-11"
                     /label="NRPS-E2"
                     /locus_tag="MOE80_RS21175"
                     /protein_end="903"
                     /protein_start="881"
                     /score="35.4"
                     /tool="antismash"
                     /translation="LFLAIHHLVVDGVAWRILLEDL"
     CDS_motif       3119..3166
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS21175_0008"
                     /evalue="5.80E-09"
                     /label="NRPS-E5"
                     /locus_tag="MOE80_RS21175"
                     /protein_end="1054"
                     /protein_start="1038"
                     /score="27.9"
                     /tool="antismash"
                     /translation="DISRTVGWFTSMYPAL"
     aSDomain        3191..3652
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE80_RS21175_TIGR01720.1"
                     /evalue="1.30E-52"
                     /label="MOE80_RS21175_TIGR01720.1"
                     /locus_tag="MOE80_RS21175"
                     /protein_end="1216"
                     /protein_start="1062"
                     /score="169.7"
                     /tool="antismash"
                     /translation="ELGTAVKTVKDTLGRIPNKGVGYGMLKYLTHPENKSIAFSKTPDI
                     SFNYLGQFNDIERQDSFRPSSLGSGKDITHTWKREQIIEMSAMAADKKLHFNLSYPPAL
                     FHRNTMEQLINRMEHFLRDIMKHCAGKQKAEKTLSDFSSQSLTAEDLDSI"
     CDS_motif       3215..3277
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS21175_0009"
                     /evalue="1.20E-09"
                     /label="NRPS-E6"
                     /locus_tag="MOE80_RS21175"
                     /protein_end="1091"
                     /protein_start="1070"
                     /score="30.4"
                     /tool="antismash"
                     /translation="VKDTLGRIPNKGVGYGMLKYL"
     aSDomain        3698..3787
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE80_RS21180_NRPS-COM_Nterm.1"
                     /evalue="1.80E-18"
                     /label="MOE80_RS21180_NRPS-COM_Nterm.1"
                     /locus_tag="MOE80_RS21180"
                     /protein_end="30"
                     /protein_start="0"
                     /score="57.4"
                     /tool="antismash"
                     /translation="MTKANSIQDIYPLSYMQEGMLFHSLLQKDS"
     gene            3698..>9421
                     /locus_tag="MOE80_RS21180"
                     /old_locus_tag="MOE80_21120"
     CDS             3698..>9421
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (0-30). E-value: 1.8e-18.
                     Score: 57.4. Matches aSDomain:
                     nrpspksdomains_MOE80_RS21180_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (7-304). E-value:
                     9.8e-119. Score: 387.8. Matches aSDomain:
                     nrpspksdomains_MOE80_RS21180_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (468-865). E-value:
                     1.3e-103. Score: 338.7. Matches aSDomain:
                     nrpspksdomains_MOE80_RS21180_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (971-1040). E-value: 1.1e-23. Score:
                     75.2. Matches aSDomain: nrpspksdomains_MOE80_RS21180_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1054-1333). E-value:
                     2.1e-103. Score: 337.4. Matches aSDomain:
                     nrpspksdomains_MOE80_RS21180_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1499-1897). E-value:
                     1.9e-109. Score: 357.9. Matches aSDomain:
                     nrpspksdomains_MOE80_RS21180_AMP-binding.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389713.2"
                     /locus_tag="MOE80_RS21180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE80_21120"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_268399818.1"
                     /sec_met_domain="PP-binding (E-value: 4.4e-17, bitscore:
                     49.7, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 2.6e-89, bitscore:
                     286.3, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.2e-113, bitscore:
                     366.9, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKANSIQDIYPLSYMQEGMLFHSLLQKDSQAYVEQASFTIEGKV
                     NSQFFQNSINALVARHDIFRTIFISQNVSSPQQVVLRERNIIVQENDITHLNEEKQAQF
                     IEQLKEKDRAQGFHLQKDMLMRIALIQTGESQYTCIWTFHHIMMDGWCLSIVLKEFLHI
                     YASYVNGSPISLEPVQPYGRYIKWLMEQDKEQAVSYWEHYLSGHEQQTMLPKQKKTKGR
                     SRQEHVTFSFSKEESSRLSEIAAREEVTLSTIFHTIWGILLQKYNNNDDAVFGSVISGR
                     PAEIEGIEHMVGLFINTIPIRVQGAKTPFIQLIKDMQKDSLAAEAYSYHPLYEIQARSA
                     VKQGLIDHILVFENYPVQQEIQMLNKQEHASDLFQIHNFTVADETNYSFYLMVAPGEEI
                     HIKMSYDAEQHDRSFVLSVKEHLLNAVSQILNNPNLPPEEIEITTDTEKRQLIGEIADR
                     TPVYETIHAMFEKQAEKTPDAHAVIDQACTLTYKELNKSANRLARHLRTKGVARQEPVA
                     IMMERSAALITGVLGILKAGGAIVPIDPHYPADRIRYILNDCGCSHVVSQAHLSASLDN
                     NYLITHAEDIESTEDGSNIKSVNNADDLLYMIYTSGTTGKPKGVQFEHRNMANLLKFEF
                     AHSGIDFEADVLQFATPAFDVCYQEIFSALLKGGTLHIVPEAIKRDVPQLFAFINKHQT
                     NIVFLPTAFIKMIFSERQLANSFPYGVKHLITAGEQLIISDIFQDVLRERGIHLHNHYG
                     PSETHVVSTYTIHPGDPIPEFPPIGKPIGCTDLYILNHQKQLQPCGVPGELYISGASVA
                     RGYVNHDKLTRDKFSSDPFRPGAIMYRTGDLARRLGDGNIEYIGRADKQVKIRGYRIEP
                     QEIEVTLMNHPDIKEAAILIRQDQNGEHELCAYYCSVQKLNAIDLRSYMASELPEYMIP
                     AKWIWVDSIPLTPNGKVDQAALPAPDASISGNPYAAPRNLIEAKLSQIFEDVLKNGHIG
                     IQDNFFDHGGHSLKATVLMSRIAKEFHVQVPLKDIFAHPTVEGLALIIQDAEENPYAAI
                     EPAVERKTYPVSSAQKRIYVLQQLDEGVAYNMPAVLELEGALDVAKLSAVCKELISRHE
                     PLRTSFVSGADGEPVQRIHTEVPFTLSTETAIEGFIRPFDLSQAPLFRAGLIKVTNEKH
                     VLLVDMHHIISDGVSVQLLIREFTDLYANRQLKPLRIQYKDYAVWQQQFKKGDSYQKQE
                     TYWLQQFSGDLPALELPTDKRRPAERHFTGGKVTFQLDKEITARIKRLANKNRSTLYMT
                     LLALYSAFLSRLSGQDDIVIGSPIAGRPHADLEAVLGMFVNTLALRTRPAGNMTFEEFL
                     KEVRQTALEAYEHQDYPFEELVDKLGVQREMSRNPLFDTTLVLQNMEQQKLKMKDVQLR
                     WNDLQHPISKFDISLYVTEHDSELFCQFEYSTALFEKETIQRWAGLFTTLVEHTAVSPE
                     TELDDIPLLTKEEERAFIESCHPFQETGYPMNQTLHYALEQQAAKTPDQPAVIFEHGAM
                     TYKELNEQANRIAWELIGRGVKSETTVAIIGKRSPEMLIGIYGILKAGGAYLPIDPDYP
                     EERISFLLEDSGTDILLLQSSSLHVPAFAGEIVYLNQANKHRLSNPNVDVLPKSLAYVI
                     YTSGSTGRPKGVEVEHRAAVNFLNSLQSRYRLKQSDVIMHKTSYSFDASIWELFWWPYA
                     GASVYLLPQGGEKEPEVIAKAIEEQEITAMHFVPSMLHAFLEHIKYRPVPIKINGLKRV
                     FSGGEQLGTHLVSRFCELLSGVALTNSYGPTEATVEAAFFDCPLHEKLERVPIGKSVHH
                     VRLYILNQKQRMLPAGCIGELYIAGAGVARGYLNRPALTEERFLEDPFYPGERMYKTGD
                     LARWLPDGHVEFLGRLDDQVKIRGYRIEPGEIEA"
     aSDomain        3719..4609
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE80_RS21180_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="9.80E-119"
                     /label="MOE80_RS21180_Condensation_DCL.1"
                     /locus_tag="MOE80_RS21180"
                     /protein_end="304"
                     /protein_start="7"
                     /score="387.8"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIMMDG"
                     /tool="antismash"
                     /translation="QDIYPLSYMQEGMLFHSLLQKDSQAYVEQASFTIEGKVNSQFFQN
                     SINALVARHDIFRTIFISQNVSSPQQVVLRERNIIVQENDITHLNEEKQAQFIEQLKEK
                     DRAQGFHLQKDMLMRIALIQTGESQYTCIWTFHHIMMDGWCLSIVLKEFLHIYASYVNG
                     SPISLEPVQPYGRYIKWLMEQDKEQAVSYWEHYLSGHEQQTMLPKQKKTKGRSRQEHVT
                     FSFSKEESSRLSEIAAREEVTLSTIFHTIWGILLQKYNNNDDAVFGSVISGRPAEIEGI
                     EHMVGLFINTIPIRVQ"
     aSModule        3719..6817
                     /complete
                     /domains="nrpspksdomains_MOE80_RS21180_Condensation_DCL.1"
                     /domains="nrpspksdomains_MOE80_RS21180_AMP-binding.1"
                     /domains="nrpspksdomains_MOE80_RS21180_PCP.1"
                     /locus_tags="MOE80_RS21180"
                     /monomer_pairings="Pro -> Pro"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       3728..3769
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS21180_0001"
                     /evalue="8.80E-05"
                     /label="C1_DCL_004-017"
                     /locus_tag="MOE80_RS21180"
                     /protein_end="24"
                     /protein_start="10"
                     /score="14.5"
                     /tool="antismash"
                     /translation="YPLSYMQEGMLFHS"
     CDS_motif       3791..3904
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS21180_0002"
                     /evalue="1.10E-14"
                     /label="C2_DCL_024-062"
                     /locus_tag="MOE80_RS21180"
                     /protein_end="69"
                     /protein_start="31"
                     /score="46.6"
                     /tool="antismash"
                     /translation="AYVEQASFTIEGKVNSQFFQNSINALVARHDIFRTIFI"
     CDS_motif       4124..4189
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS21180_0003"
                     /evalue="5.00E-11"
                     /label="C3_DCL_135-156"
                     /locus_tag="MOE80_RS21180"
                     /protein_end="164"
                     /protein_start="142"
                     /score="35.0"
                     /tool="antismash"
                     /translation="FHHIMMDGWCLSIVLKEFLHIY"
     CDS_motif       4235..4273
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS21180_0004"
                     /evalue="1.80E-02"
                     /label="C4_DCL_171-183"
                     /locus_tag="MOE80_RS21180"
                     /protein_end="192"
                     /protein_start="179"
                     /score="8.2"
                     /tool="antismash"
                     /translation="PYGRYIKWLMEQD"
     CDS_motif       4508..4603
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS21180_0005"
                     /evalue="8.40E-20"
                     /label="C5_DCL_263-294"
                     /locus_tag="MOE80_RS21180"
                     /protein_end="302"
                     /protein_start="270"
                     /score="63.2"
                     /tool="antismash"
                     /translation="DAVFGSVISGRPAEIEGIEHMVGLFINTIPIR"
     CDS_motif       4649..4765
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS21180_0006"
                     /evalue="3.50E-21"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="MOE80_RS21180"
                     /protein_end="356"
                     /protein_start="317"
                     /score="67.7"
                     /tool="antismash"
                     /translation="QKDSLAAEAYSYHPLYEIQARSAVKQGLIDHILVFENYP"
     aSDomain        5102..6292
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE80_RS21180_AMP-binding.1"
                     /evalue="1.30E-103"
                     /label="MOE80_RS21180_AMP-binding.1"
                     /locus_tag="MOE80_RS21180"
                     /protein_end="865"
                     /protein_start="468"
                     /score="338.7"
                     /specificity="substrate consensus: Pro"
                     /tool="antismash"
                     /translation="FEKQAEKTPDAHAVIDQACTLTYKELNKSANRLARHLRTKGVARQ
                     EPVAIMMERSAALITGVLGILKAGGAIVPIDPHYPADRIRYILNDCGCSHVVSQAHLSA
                     SLDNNYLITHAEDIESTEDGSNIKSVNNADDLLYMIYTSGTTGKPKGVQFEHRNMANLL
                     KFEFAHSGIDFEADVLQFATPAFDVCYQEIFSALLKGGTLHIVPEAIKRDVPQLFAFIN
                     KHQTNIVFLPTAFIKMIFSERQLANSFPYGVKHLITAGEQLIISDIFQDVLRERGIHLH
                     NHYGPSETHVVSTYTIHPGDPIPEFPPIGKPIGCTDLYILNHQKQLQPCGVPGELYISG
                     ASVARGYVNHDKLTRDKFSSDPFRPGAIMYRTGDLARRLGDGNIEYIGRADKQVKIR"
     CDS_motif       5288..5329
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS21180_0007"
                     /evalue="2.80E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="MOE80_RS21180"
                     /protein_end="544"
                     /protein_start="530"
                     /score="14.3"
                     /tool="antismash"
                     /translation="LGILKAGGAIVPID"
     CDS_motif       5513..5569
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS21180_0008"
                     /evalue="1.40E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="MOE80_RS21180"
                     /protein_end="624"
                     /protein_start="605"
                     /score="26.9"
                     /tool="antismash"
                     /translation="YMIYTSGTTGKPKGVQFEH"
     CDS_motif       5951..5977
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS21180_0009"
                     /evalue="4.20E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="MOE80_RS21180"
                     /protein_end="760"
                     /protein_start="751"
                     /score="4.2"
                     /tool="antismash"
                     /translation="YGPSETHVV"
     CDS_motif       6086..6175
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS21180_0010"
                     /evalue="5.20E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="MOE80_RS21180"
                     /protein_end="826"
                     /protein_start="796"
                     /score="41.2"
                     /tool="antismash"
                     /translation="PCGVPGELYISGASVARGYVNHDKLTRDKF"
     CDS_motif       6257..6322
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS21180_0011"
                     /evalue="1.60E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="MOE80_RS21180"
                     /protein_end="875"
                     /protein_start="853"
                     /score="36.1"
                     /tool="antismash"
                     /translation="YIGRADKQVKIRGYRIEPQEIE"
     aSDomain        6611..6817
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE80_RS21180_PCP.1"
                     /evalue="1.10E-23"
                     /label="MOE80_RS21180_PCP.1"
                     /locus_tag="MOE80_RS21180"
                     /protein_end="1040"
                     /protein_start="971"
                     /score="75.2"
                     /tool="antismash"
                     /translation="EAKLSQIFEDVLKNGHIGIQDNFFDHGGHSLKATVLMSRIAKEFH
                     VQVPLKDIFAHPTVEGLALIIQDA"
     aSDomain        6860..7696
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE80_RS21180_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="2.10E-103"
                     /label="MOE80_RS21180_Condensation_LCL.1"
                     /locus_tag="MOE80_RS21180"
                     /protein_end="1333"
                     /protein_start="1054"
                     /score="337.4"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIISDG"
                     /tool="antismash"
                     /translation="KTYPVSSAQKRIYVLQQLDEGVAYNMPAVLELEGALDVAKLSAVC
                     KELISRHEPLRTSFVSGADGEPVQRIHTEVPFTLSTETAIEGFIRPFDLSQAPLFRAGL
                     IKVTNEKHVLLVDMHHIISDGVSVQLLIREFTDLYANRQLKPLRIQYKDYAVWQQQFKK
                     GDSYQKQETYWLQQFSGDLPALELPTDKRRPAERHFTGGKVTFQLDKEITARIKRLANK
                     NRSTLYMTLLALYSAFLSRLSGQDDIVIGSPIAGRPHADLEAVLGMFVNTLALRTRP"
     aSModule        6860..9388
                     /domains="nrpspksdomains_MOE80_RS21180_Condensation_LCL.1"
                     /domains="nrpspksdomains_MOE80_RS21180_AMP-binding.2"
                     /incomplete
                     /locus_tags="MOE80_RS21180"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       6926..7039
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS21180_0012"
                     /evalue="6.70E-15"
                     /label="C2_LCL_024-062"
                     /locus_tag="MOE80_RS21180"
                     /protein_end="1114"
                     /protein_start="1076"
                     /score="47.4"
                     /tool="antismash"
                     /translation="AYNMPAVLELEGALDVAKLSAVCKELISRHEPLRTSFV"
     CDS_motif       7211..7276
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS21180_0013"
                     /evalue="1.70E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="MOE80_RS21180"
                     /protein_end="1193"
                     /protein_start="1171"
                     /score="30.1"
                     /tool="antismash"
                     /translation="MHHIISDGVSVQLLIREFTDLY"
     CDS_motif       7307..7339
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS21180_0014"
                     /evalue="9.50E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="MOE80_RS21180"
                     /protein_end="1214"
                     /protein_start="1203"
                     /score="11.9"
                     /tool="antismash"
                     /translation="QYKDYAVWQQQ"
     CDS_motif       7598..7687
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS21180_0015"
                     /evalue="2.50E-16"
                     /label="C5_LCL_267-296"
                     /locus_tag="MOE80_RS21180"
                     /protein_end="1330"
                     /protein_start="1300"
                     /score="51.9"
                     /tool="antismash"
                     /translation="DIVIGSPIAGRPHADLEAVLGMFVNTLALR"
     CDS_motif       7736..7855
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS21180_0016"
                     /evalue="6.20E-21"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="MOE80_RS21180"
                     /protein_end="1386"
                     /protein_start="1346"
                     /score="66.8"
                     /tool="antismash"
                     /translation="RQTALEAYEHQDYPFEELVDKLGVQREMSRNPLFDTTLVL"
     aSDomain        8195..9388
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE80_RS21180_AMP-binding.2"
                     /evalue="1.90E-109"
                     /label="MOE80_RS21180_AMP-binding.2"
                     /locus_tag="MOE80_RS21180"
                     /protein_end="1897"
                     /protein_start="1499"
                     /score="357.9"
                     /specificity="substrate consensus: Glu"
                     /tool="antismash"
                     /translation="LEQQAAKTPDQPAVIFEHGAMTYKELNEQANRIAWELIGRGVKSE
                     TTVAIIGKRSPEMLIGIYGILKAGGAYLPIDPDYPEERISFLLEDSGTDILLLQSSSLH
                     VPAFAGEIVYLNQANKHRLSNPNVDVLPKSLAYVIYTSGSTGRPKGVEVEHRAAVNFLN
                     SLQSRYRLKQSDVIMHKTSYSFDASIWELFWWPYAGASVYLLPQGGEKEPEVIAKAIEE
                     QEITAMHFVPSMLHAFLEHIKYRPVPIKINGLKRVFSGGEQLGTHLVSRFCELLSGVAL
                     TNSYGPTEATVEAAFFDCPLHEKLERVPIGKSVHHVRLYILNQKQRMLPAGCIGELYIA
                     GAGVARGYLNRPALTEERFLEDPFYPGERMYKTGDLARWLPDGHVEFLGRLDDQVKIR"
     CDS_motif       8384..8422
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS21180_0017"
                     /evalue="8.10E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="MOE80_RS21180"
                     /protein_end="1575"
                     /protein_start="1562"
                     /score="15.9"
                     /tool="antismash"
                     /translation="GILKAGGAYLPID"
     CDS_motif       8600..8659
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS21180_0018"
                     /evalue="2.70E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="MOE80_RS21180"
                     /protein_end="1654"
                     /protein_start="1634"
                     /score="32.1"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGRPKGVEVEH"
     CDS_motif       9044..9073
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS21180_0019"
                     /evalue="4.00E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="MOE80_RS21180"
                     /protein_end="1792"
                     /protein_start="1782"
                     /score="7.0"
                     /tool="antismash"
                     /translation="SYGPTEATVE"
     CDS_motif       9182..9271
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS21180_0020"
                     /evalue="5.30E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="MOE80_RS21180"
                     /protein_end="1858"
                     /protein_start="1828"
                     /score="57.0"
                     /tool="antismash"
                     /translation="PAGCIGELYIAGAGVARGYLNRPALTEERF"
     CDS_motif       9353..9418
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS21180_0021"
                     /evalue="1.10E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="MOE80_RS21180"
                     /protein_end="1907"
                     /protein_start="1885"
                     /score="39.8"
                     /tool="antismash"
                     /translation="FLGRLDDQVKIRGYRIEPGEIE"
ORIGIN
        1 gtttgtgaac acgctggcgc ttcggacacg cccggagggc gggaagccgt ttgtggagta
       61 tttgcaggaa gtgcgcgaca cagcattggg agcctacgag catcaggatt atccgttcga
      121 agagctcgtc gacaagctta aattgacgcg ggatatgagc cggaatccgc tgtttgacgt
      181 gatgtttgtt cttcaaaata tggatcagga atcgattcag cttgaagaac tgcatctcaa
      241 acctgcagca aacaacgggc atcaaacgtc caaatttgat ttaactctgt atgctcacga
      301 acagccctgc ggtttgctga cgttccaaat ggaatttagt acggacttat ataagaaaaa
      361 aacgatagaa aagtggcttc aatacttcat caatatgtta ctctccatca cccaagacaa
      421 caaagccgct ctcggaacaa taaatatact aaatgaggat gagacccatt accttatcca
      481 tgagctcaat cgtacaaaaa tagattatcc aagaaatgaa accatcagca ggctcttcga
      541 aatgcaggct gaacaaacac ctaatgccat tgcaattgtc agcgatacac aagaattaac
      601 ttacgcggat ctgaacagcc gggcaaatca aattgcttca gttctacaga gaaagggagt
      661 agggcctgat cgtgttgtag ccttgttgac aggacgaacg ccagaactca tagcgggaat
      721 gctgggtatt ctgaaagccg gaggagccta cctgccaatc gcacctgatc tgcctgttga
      781 acgaatagct tatatgctgt cagacagcgg ggcaacatta ctccttcgat ctgaaaaagc
      841 agaaaaacgg caattagaca ttgcatgtga acaattcata atcgaagaca ttcaaaagca
      901 aggagaaaca aagaacattg aatcgtcagc agggccacat tcacttgcat atatcattta
      961 tacctctgga tcaaccggta aaccaaaggg tgtcatgatt gagcagcgaa gtgtcattcg
     1021 tcttgttaaa aacagcaatt atattacatt tacacctgca gaccgtcttc tcatgacatc
     1081 atcaatcggt tttgatgttg tgacatttga aatatttgga ccgctgctaa atggggcagc
     1141 tttgcacctg tccgataaag aagtatttct cgattcctat cagcttcaga gatacataga
     1201 acatcatggg atcacaacga tgtggttgac atcttctcta ttcaatcatt taacagagca
     1261 aaatgagaca accttttcac agctgaatca tctgattata ggcggggaag ccttgtccgc
     1321 aagccacgtc aatcgaatcc gaaatgtctg cccggaagta tcgatatgga acggatatgg
     1381 accaaccgaa aatacaactt tttcgacatg cttccacatt caaaaaacat atgaactttc
     1441 catcccgatc gggcggccgg ttggtaattc caccacttat atcttaaata aatggggaat
     1501 gctgcagcct atcggagctg tcggtgaact ttgtgtcggc ggtgatggcg tcgccagagg
     1561 ctatttaggc cgtcctgatt taacaaaaga gaaatttgtc ccaaatccat ttgcgcctgg
     1621 cgatcgactg taccgcacag gtgatctggc gcgttggctt cccgatggca caattgagta
     1681 cgttggccgt atagatgatc aagtaaaagt cagaggctat cgggtggagc tgggtgagat
     1741 cgaatcagca cttcgccaaa tagacggggt caaagaagcc gctgtgttgg cacgtacagg
     1801 ccagacgggg agcaaagagc tgtttggcta catcagcgta aatgcaggca cgaatgctga
     1861 acaagtgcgt tctcttctcg cgcgttcact gccaaattat atgatcccgg cgtacatcat
     1921 tgaaatggag actcttccgc tcacatcaaa cggcaaattg aaccggaaag cacttcctga
     1981 accagatttc gcatctaaac aaacgtacgt cccgccacgc gatgaccttg aagaacagct
     2041 ggcattgatc tggcaggagg ttcttggcat ccagaggatc ggaatagagg attcgttttt
     2101 tgaattgggc ggagattcaa tcaaagcgct tcaagtttct gcacgccttg gacgccatgg
     2161 gctaagcttg caggtaagtg atttattccg gcatccaaag ataaaagact tatcaccatt
     2221 tatccgtaag acagagagaa tcatagaaca aggccccatt cagggagacg ttccttggac
     2281 gcctgttcag caatggtttc tttcacaaga tattgaagaa cgacaccatt ttaatcagtc
     2341 tgtcatgctt ttccattctg accgtttgtc tgaagacgcc cttagagcag ccttaaaaaa
     2401 actggcggag catcatgatg cgcttcggat ggtttatcgt aacgatgacg ggcgatggat
     2461 tcaaattaac caaggcattc aggaatcaca gctgtacagt ttaagaatat ctgatctttc
     2521 acagtccgaa agcggttggg aaacgcaaat caaacaagaa gttgcagatc ttcagcaaag
     2581 catcaatttg caggaaggac cattgttaca tgccgcgtgg tttaaaacac tgacaggaga
     2641 ttacttgttc cttgcgatcc atcatcttgt cgttgacggt gtggcatggc ggattttgct
     2701 ggaggatttg tcagcagggt accaacaagc atcttcaggc caggcgattc agcttccgcc
     2761 taaaactgat tcctaccagg aatacgcaag acggatacag gaatatgccc aaagcagcag
     2821 gctgattcgt gaggaggcgt attggcgaac tgtggaagaa cagcaagctg cggaactgcc
     2881 atatgaaatg ccgcttcatg agaacaccga cttcagcaga agggattcga tacgcttttc
     2941 actctctgaa acagacactg ccgttttgct gcaaaacgtc aatcacgcct atggtacaga
     3001 tacacaagat attctgttaa ccgcagcatc cttggcgatt tgtgaatgga caggcggaag
     3061 caagctccgt atcgctatgg aaggacacgg gagagaacac attctgccag agttagatat
     3121 cagccggacg gtcggctggt ttacatccat gtacccggcc ctcataagct ttgaaaatca
     3181 tagggatgag ctcggaaccg cagtaaaaac cgttaaagat acactgggcc ggataccaaa
     3241 caaaggggta ggttacggta tgctgaaata ccttacacac cctgaaaaca aaagcattgc
     3301 gttttcaaaa acacctgaca tcagctttaa ctatttgggc cagttcaacg acatcgaaag
     3361 acaggacagc ttccgcccat caagtcttgg gagcggaaag gatatcactc atacatggaa
     3421 gcgtgagcaa atcatcgaga tgagtgcaat ggcagcagac aaaaagctcc atttcaatct
     3481 tagttatccg ccagccctct ttcatagaaa cacaatggag cagcttatca acaggatgga
     3541 acactttttg cgggacatta tgaaacattg cgccggtaaa cagaaagcag aaaagacact
     3601 gagcgatttt agcagtcaat cattaacggc agaggatttg gacagcatat ccagcttggt
     3661 ggaagaattg tagaaaatcg gacagggaga catgaacatg acaaaagcga attcaattca
     3721 ggatatttat ccgctgtctt acatgcagga agggatgctt ttccattccc tcctgcaaaa
     3781 agattcacag gcatatgttg agcaagcttc ttttacaata gaaggaaaag tcaactcgca
     3841 gttttttcaa aacagcatca acgctcttgt agcaagacac gatattttca gaacgatttt
     3901 tatcagccaa aatgtttcct ctccccagca ggttgtcctg agagaacgga acatcatcgt
     3961 acaggaaaat gacattactc atttaaacga agagaagcaa gcacagttta tcgaacaatt
     4021 gaaagaaaaa gaccgcgccc aagggtttca cttgcaaaag gatatgctca tgcgcatcgc
     4081 tctgattcaa acaggagaga gccagtacac ttgtatttgg acctttcatc acatcatgat
     4141 ggacggctgg tgcctcagca ttgtgctaaa ggagtttctc catatttacg catcttatgt
     4201 aaatggctcc cctatatcat tggagccggt ccagccatac ggaaggtata tcaaatggct
     4261 gatggagcaa gacaaagagc aggcagtttc atattgggaa cattatcttt ccggccatga
     4321 acagcaaacc atgctcccga agcagaaaaa aacaaagggg agaagcaggc aggaacacgt
     4381 tacgttttca ttctctaagg aagaaagcag caggctttcg gagattgcgg caagagaaga
     4441 agtaacactc agtacgattt tccataccat ttggggtatt ctgcttcaaa aatataataa
     4501 taacgatgac gccgtattcg gttctgtcat ttcaggaaga cccgcagaaa tcgaaggcat
     4561 tgaacatatg gtaggtcttt tcattaacac gataccgatt agggtgcaag gggcaaaaac
     4621 accatttata cagctcataa aagatatgca aaaagacagt cttgccgctg aagcatacag
     4681 ctaccaccct ttatatgaga ttcaagcccg ttcagctgtt aaacaagggc tgattgatca
     4741 tattctcgta tttgaaaact atcctgttca gcaagagatt cagatgctga acaagcagga
     4801 acatgcttct gatctttttc agattcataa cttcactgtg gcagatgaaa ccaactacag
     4861 cttttatctt atggtggcgc caggagaaga aatccatatt aaaatgagct atgatgcgga
     4921 gcagcatgat cggtcttttg tgctttctgt caaggagcat cttctgaatg ctgtatcaca
     4981 aatcttaaat aatccgaatc ttccgcctga agaaatcgag atcacgacag atactgaaaa
     5041 gcggcagctg attggggaaa tcgcggatcg aacgccagtt tacgaaacca tccatgcgat
     5101 gtttgaaaaa caagcggaaa agaccccaga tgctcatgca gtaattgatc aagcctgcac
     5161 gttaacatac aaagaactga ataaatcggc taacagattg gcacggcatt tgcgaacgaa
     5221 gggtgttgcg aggcaggagc ctgttgcgat catgatggaa cgctctgcgg cattgatcac
     5281 cggggttctt ggtatcttga aagcaggcgg cgccatagtt ccaattgatc cgcattaccc
     5341 ggctgacaga atccgttata ttctaaatga ctgcggctgt tcgcatgttg tttcacaagc
     5401 gcacctttcc gcatcgcttg ataacaatta ccttatcact catgccgaag atattgaaag
     5461 cacagaagac ggcagtaaca taaagtcagt caacaatgcg gacgatttgc tgtatatgat
     5521 ttatacatca ggtacaacag gtaaaccaaa gggcgttcaa tttgaacatc gaaacatggc
     5581 taacttgctg aagttcgaat ttgctcactc tgggattgac tttgaagcag atgttctgca
     5641 atttgcgaca cctgcctttg acgtctgtta tcaagaaata ttttctgcgc ttctgaaagg
     5701 cggcaccctg cacatcgtgc cagaagccat aaaaagagat gtgcctcagc tgtttgcatt
     5761 tataaacaag catcagacga atattgtgtt tctcccaacg gcttttatca aaatgatttt
     5821 cagcgagcgg caacttgcga actcgtttcc ttatggcgtc aaacacttga ttacagctgg
     5881 ggaacaatta attatttcag acattttcca agacgtgtta cgtgaacgcg gcatacacct
     5941 gcacaatcat tacggacctt cagaaactca tgtggtatct acgtacacca ttcatccggg
     6001 agaccctatt cctgagtttc cgccaatcgg taaaccgata ggctgtactg atctatatat
     6061 tttgaatcac caaaaacagc tacagccatg cggtgtacca ggtgaactct atatttccgg
     6121 cgcaagtgtt gccagaggat atgtcaatca cgataaactg acacgcgaca aattttcatc
     6181 tgacccattc aggcctggtg cgatcatgta ccgtacaggt gatttggcca gacggcttgg
     6241 agacggcaac atcgaatata taggacgggc agacaagcaa gtgaaaatca gaggttatcg
     6301 aatcgagccg caagaaatcg aagtcacgtt aatgaatcat ccggacatta aagaggctgc
     6361 cattctcatc agacaagatc aaaacggaga acatgaatta tgcgcttact attgcagtgt
     6421 acaaaagctg aatgcaatag atttacgcag ctatatggct agtgagctac cagaatacat
     6481 gattccggcg aaatggatat gggttgacag catacctctt accccaaacg gaaaagtaga
     6541 tcaagcagcg cttccagcgc cagatgcttc aatcagcgga aatccatatg ctgcccctcg
     6601 taatctgata gaggcaaagc tttcacaaat atttgaagat gtgctgaaga atggtcatat
     6661 aggcatccaa gacaactttt ttgaccatgg aggccactct ctaaaagcaa cagtactgat
     6721 gtcacggatc gcaaaggaat ttcatgtaca agttccgctt aaggacatct ttgcccatcc
     6781 gactgtagaa ggattggctt taatcattca agatgcagag gaaaatccgt atgcagcaat
     6841 tgagccggca gtagaaagga agacatatcc tgtatcttcg gcacaaaaac ggatatatgt
     6901 gcttcagcag cttgatgagg gtgtcgccta caatatgcct gcggtcttag aactggaagg
     6961 ggcactggat gtcgctaaac tgtctgctgt atgtaaagaa ctgatcagcc ggcatgagcc
     7021 tcttcgaact tcctttgtat ccggggcaga tggcgagcct gttcagcgta tccacaccga
     7081 agtgccgttt acattaagta cagagaccgc tatcgagggg tttatccgcc cctttgatct
     7141 cagccaggcg ccattattta gagcgggcct tataaaagtg acgaacgaga agcatgtatt
     7201 gctggttgac atgcatcata tcatttcaga tggcgtatcc gttcagctcc taatccgaga
     7261 attcaccgat ctttatgcaa accgccagct taagccattg cggatccagt ataaagatta
     7321 cgccgtttgg cagcagcaat ttaaaaaggg agactcgtac caaaagcagg agacttactg
     7381 gctgcagcag tttagcgggg acctccctgc actagagctt ccgacagata aacgccgccc
     7441 ggcagaacgg cactttacag gcggaaaagt aacctttcaa ttggataaag agatcacggc
     7501 ccgcataaag cggcttgcca ataaaaacag aagcacgctt tatatgacgc ttcttgcttt
     7561 gtattcagcc tttttgtcgc ggttaagcgg tcaggatgat atcgtaattg gttcacctat
     7621 cgccggacgg ccccatgccg accttgaagc tgttcttggg atgttcgtca atacattggc
     7681 tctccgcaca cgcccggccg gtaatatgac atttgaagag tttctgaaag aagtcagaca
     7741 gacagcatta gaagcgtatg agcatcagga ttacccgttt gaagagcttg tggataaact
     7801 cggtgtgcag cgagaaatga gccgaaatcc attgtttgac acaacgctag tccttcagaa
     7861 tatggaacag caaaagctga aaatgaaaga tgtacagctt cgatggaacg atttgcagca
     7921 tccaatatcg aaatttgata tttctctgta tgttacagaa cacgattccg agcttttctg
     7981 tcagtttgaa tacagtacag ctttgtttga gaaagaaacc atccaaaggt gggccggcct
     8041 tttcaccacg cttgtggaac atacagctgt cagccctgaa acagaattgg acgatattcc
     8101 actcttaaca aaagaagaag agagagcttt cattgaatca tgccatccgt ttcaggagac
     8161 gggctatccg atgaatcaaa ctctccacta tgcacttgaa cagcaggcag caaaaacgcc
     8221 tgatcagccg gccgttatct ttgaacatgg agcgatgacc tataaagagt tgaacgaaca
     8281 ggctaaccgt atcgcctggg agctgatcgg acgaggagta aaatctgaaa cgactgttgc
     8341 cattatagga aagcgttcgc ctgaaatgct gattggcatt tatggcattc ttaaagctgg
     8401 cggcgcttat cttcctattg acccggatta cccggaagaa cgaatcagct ttctgctgga
     8461 ggacagcggt acagacattc tcctgcttca gtcttccagc ctgcatgttc cggcatttgc
     8521 aggagagatt gtctacctca atcaggcaaa taaacatcgt ttgtccaatc cgaatgtgga
     8581 cgttctccct aaatctttag cctatgtcat ctatacatcc ggctctaccg gcaggcctaa
     8641 gggtgtggaa gttgaacatc gagctgcggt gaattttttg aattcccttc agtcccgcta
     8701 tcggctgaag caatcagatg tgattatgca taaaacatct tactcatttg acgcttccat
     8761 atgggagctg ttttggtggc cttatgccgg tgcttccgtt tatctgcttc ctcagggagg
     8821 ggaaaaagaa cctgaagtga tcgcgaaggc catagaagaa caagagatca cagctatgca
     8881 ttttgtgcca tctatgcttc atgcattttt agaacatata aaatatcgcc ctgtaccgat
     8941 taaaataaac ggactcaaac gggtgttttc cgggggagaa cagctgggga cccatctcgt
     9001 ctcccgtttt tgcgagttac tttcaggtgt tgcattaacc aattcttacg gaccaacgga
     9061 ggcaactgta gaagctgcgt tctttgattg tccgctgcat gaaaagcttg aacgcgttcc
     9121 aattggaaaa tctgttcatc atgtcagatt gtatatcctc aatcagaagc agcggatgct
     9181 gcctgctgga tgtatcggag aactgtacat tgccggagcg ggtgtggcca gaggctattt
     9241 gaatcggccg gccttaacgg aggagcgttt tcttgaggac ccgttttacc cgggtgaacg
     9301 catgtacaaa accggggatt tggcgcgctg gcttcctgac ggacatgttg aattcctcgg
     9361 ccgtttggat gatcaagtca aaatcagggg ctaccgtatc gagcctggag aaattgaagc
     9421 a
//
