LOCUS       NZ_JALAVI010000016     14531 bp    DNA     linear   CON 26-JAN-2024
DEFINITION  Bacillus inaquosorum strain EC30O4B-A7 contig_0000016, whole genome
            shotgun sequence.
ACCESSION   NZ_JALAVI010000016
VERSION     NZ_JALAVI010000016.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus inaquosorum
  ORGANISM  Bacillus inaquosorum
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 14531)
  AUTHORS   Dunlap,C.
  TITLE     Crop Bioprotection Bacillus Genome Sequencing
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 14531)
  AUTHORS   Dunlap,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-FEB-2022) CBP, USDA-ARS-NCAUR, 1815 N. University St.,
            Peoria, IL 61604, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC NGS Cell v. 21
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 168.96085678627867x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/24/2024 02:36:42
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,244
            CDSs (total)                      :: 4,173
            Genes (coding)                    :: 4,038
            CDSs (with protein)               :: 4,038
            Genes (RNA)                       :: 71
            rRNAs                             :: 4, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 3 (5S)
            tRNAs                             :: 60
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 86 of 135
            Pseudo Genes (incomplete)         :: 70 of 135
            Pseudo Genes (internal stop)      :: 30 of 135
            Pseudo Genes (multiple problems)  :: 40 of 135
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:28:30
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 14531
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JALAVI010000016.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..14531
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     gene            <1..4162
                     /locus_tag="MOE80_RS17705"
                     /old_locus_tag="MOE80_17655"
     source          1..14531
                     /db_xref="taxon:483913"
                     /mol_type="genomic DNA"
                     /organism="Bacillus inaquosorum"
                     /strain="EC30O4B-A7"
                     /submitter_seqid="contig_0000016"
     cand_cluster    1..14531
                     /SMILES="NC(CCCN)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(C(O)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..14531
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<2:>14531](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      <3..>14531
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     CDS             <3..4162
                     /NRPS_PKS="Domain: Condensation_LCL (0-162). E-value:
                     1.2e-66. Score: 216.7. Matches aSDomain:
                     nrpspksdomains_MOE80_RS17705_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (328-733). E-value:
                     6.6e-101. Score: 329.8. Matches aSDomain:
                     nrpspksdomains_MOE80_RS17705_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (838-902). E-value: 9.8e-23. Score:
                     72.1. Matches aSDomain: nrpspksdomains_MOE80_RS17705_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (914-1225). E-value:
                     5.8e-144. Score: 472.6. Matches aSDomain:
                     nrpspksdomains_MOE80_RS17705_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (1233-1378). E-value: 6.9e-46.
                     Score: 147.8. Matches aSDomain:
                     nrpspksdomains_MOE80_RS17705_TIGR01720.1"
                     /codon_start=2
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389716.2"
                     /locus_tag="MOE80_RS17705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE80_17655"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_268399486.1"
                     /sec_met_domain="AMP-binding (E-value: 1.4e-110, bitscore:
                     357.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.6e-17, bitscore:
                     51.7, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 6.8e-87, bitscore:
                     278.9, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHHIISDGVSVNILIREFGELYNNRTLPALHIQYKDYAVWQEGFK
                     KGDAYQTQEAYWLKQLEGELPVLDLPADHTRPPVRSFAGDKVSFTLDQEAASGLHKLAR
                     ENGSTLYMVLLAAYTALLSRLSGQEDIIVGSPIAGRPHKDLEPILGMFVNTLALRTRPE
                     GGKPFVQYLQEVRETALEAYEHQDYPFEELVDKLKLTRDMSRNPVFDAMFILQNMEKQD
                     MDLEEIKVRPANFAHHISLFDITLIATETDGAICCELEFSTEVFLKATIERWAAHFIEF
                     LHAALSNPETNLSQINILSHQEKQKIVFEFNKTQIEFSQKDVPFHRIFEARAEETPEHI
                     AVIDDETQISYRLLNERANRLARTLQKRKGAKPTVAVLAKRSIDAIVGILAVMKAGGVY
                     IPIDSHYPKARIEYLLRDSEADILLLQQELKHLISNSSECDISHICLDDESSYEENSCN
                     LDLSPAPEDVAYIIYTSGTTGAPKGVIVTYRNFTHAALAWRQIYELDRKPVRLLQMASF
                     SFDVFSGDLARTLINGGTLIVCPDEKRLEPAELYGIMNSRRITIMESTPALIIPIMEYV
                     YRNKLKLPDLDILILGSDMVKAQDFKTLTERFGQSMRIINSYGVTEATIDSSCYETRMG
                     EEYTGDNVPIGSPLPNVHMYVLSQTNQIQPIGVAGELCISGAGVAKGYHNKPDLTQMKF
                     TENPFVSGERLYRTGDRACWLPNGTIKLLGRMDYQVKINGYRIETEEIESVLLQTGLVR
                     EAAVAVQHDKNGHAGLAAYIVPSDVNTNTLRAALTKELPAYMIPAHLIPIEKLPLTLNG
                     KLDKNALPAPNDVFTRPYTAPVNDIQKTIAEIWEDVLSIARVGIHDSFFELGGDSIKAL
                     QVAARLAAEGWSMTIRDLFRYPTIQELSGHITPLASQADQGPAEGEADLAPIQRRFFGQ
                     VHAFHYHYNQSVILFSEKGFNTNALRRALRKITEHHDAIRMVFQRNQNGHVVQYNRGMN
                     HNDHELFGLHIADWTKESLERTQFDEKLAAEEIGIQSKMNVQKGPLLQAGLFKTAEGDH
                     LLIALHHLVIDGVSWRILLEDLAAAYQQALEKQEIQLPPKTDSYLSYANGLAQIAENKQ
                     LLAEKSYWQSILDAHTAFLPKDTENVPGRLQMNSDTAAFVLSGDWTEKLLFETQQAYGT
                     NANELLLTALGMALSEWTGHDQIVISTEGHGREGHVPNIDISRTVGWFTSIYPILLDMG
                     IPEPFEDQLAYRIKTTKDMLRRVPNKGTGYGLLTHIGELPHKEPEVSFNYLGQFSEEKE
                     AETFQLSYYQPRYEIAGEREREYELDINALITDGRLQVKAVYTQVFNQHSIECFMDRFH
                     RHLIEMIEHCSQKKIREKTLSDFSNKELTLSALSSIEDLVKDL"
     CDS_motif       5..70
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17705_0001"
                     /evalue="5.10E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="MOE80_RS17705"
                     /protein_end="22"
                     /protein_start="0"
                     /score="31.8"
                     /tool="antismash"
                     /translation="MHHIISDGVSVNILIREFGELY"
     aSDomain        5..490
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE80_RS17705_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.20E-66"
                     /label="MOE80_RS17705_Condensation_LCL.1"
                     /locus_tag="MOE80_RS17705"
                     /protein_end="162"
                     /protein_start="0"
                     /score="216.7"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIISDG"
                     /tool="antismash"
                     /translation="MHHIISDGVSVNILIREFGELYNNRTLPALHIQYKDYAVWQEGFK
                     KGDAYQTQEAYWLKQLEGELPVLDLPADHTRPPVRSFAGDKVSFTLDQEAASGLHKLAR
                     ENGSTLYMVLLAAYTALLSRLSGQEDIIVGSPIAGRPHKDLEPILGMFVNTLALRTRP"
     aSModule        5..4138
                     /complete
                     /domains="nrpspksdomains_MOE80_RS17705_Condensation_LCL.1"
                     /domains="nrpspksdomains_MOE80_RS17705_AMP-binding.1"
                     /domains="nrpspksdomains_MOE80_RS17705_PCP.1"
                     /domains="nrpspksdomains_MOE80_RS17705_Epimerization.1"
                     /domains="nrpspksdomains_MOE80_RS17705_TIGR01720.1"
                     /locus_tags="MOE80_RS17705"
                     /monomer_pairings="Orn -> D-Orn"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       101..130
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17705_0002"
                     /evalue="1.30E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="MOE80_RS17705"
                     /protein_end="42"
                     /protein_start="32"
                     /score="14.6"
                     /tool="antismash"
                     /translation="QYKDYAVWQE"
     CDS_motif       329..382
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17705_0003"
                     /evalue="4.70E-02"
                     /label="Cy4"
                     /locus_tag="MOE80_RS17705"
                     /protein_end="126"
                     /protein_start="108"
                     /score="7.0"
                     /tool="antismash"
                     /translation="TLYMVLLAAYTALLSRLS"
     CDS_motif       392..481
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17705_0004"
                     /evalue="1.50E-15"
                     /label="C5_LCL_267-296"
                     /locus_tag="MOE80_RS17705"
                     /protein_end="159"
                     /protein_start="129"
                     /score="49.4"
                     /tool="antismash"
                     /translation="DIIVGSPIAGRPHKDLEPILGMFVNTLALR"
     CDS_motif       530..649
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17705_0005"
                     /evalue="8.60E-22"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="MOE80_RS17705"
                     /protein_end="215"
                     /protein_start="175"
                     /score="69.6"
                     /tool="antismash"
                     /translation="RETALEAYEHQDYPFEELVDKLKLTRDMSRNPVFDAMFIL"
     aSDomain        989..2203
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE80_RS17705_AMP-binding.1"
                     /evalue="6.60E-101"
                     /label="MOE80_RS17705_AMP-binding.1"
                     /locus_tag="MOE80_RS17705"
                     /protein_end="733"
                     /protein_start="328"
                     /score="329.8"
                     /specificity="substrate consensus: Orn"
                     /tool="antismash"
                     /translation="FEARAEETPEHIAVIDDETQISYRLLNERANRLARTLQKRKGAKP
                     TVAVLAKRSIDAIVGILAVMKAGGVYIPIDSHYPKARIEYLLRDSEADILLLQQELKHL
                     ISNSSECDISHICLDDESSYEENSCNLDLSPAPEDVAYIIYTSGTTGAPKGVIVTYRNF
                     THAALAWRQIYELDRKPVRLLQMASFSFDVFSGDLARTLINGGTLIVCPDEKRLEPAEL
                     YGIMNSRRITIMESTPALIIPIMEYVYRNKLKLPDLDILILGSDMVKAQDFKTLTERFG
                     QSMRIINSYGVTEATIDSSCYETRMGEEYTGDNVPIGSPLPNVHMYVLSQTNQIQPIGV
                     AGELCISGAGVAKGYHNKPDLTQMKFTENPFVSGERLYRTGDRACWLPNGTIKLLGRMD
                     YQVKIN"
     CDS_motif       1172..1213
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17705_0006"
                     /evalue="8.40E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="MOE80_RS17705"
                     /protein_end="403"
                     /protein_start="389"
                     /score="15.9"
                     /tool="antismash"
                     /translation="LAVMKAGGVYIPID"
     CDS_motif       1409..1465
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17705_0007"
                     /evalue="2.70E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="MOE80_RS17705"
                     /protein_end="487"
                     /protein_start="468"
                     /score="26.0"
                     /tool="antismash"
                     /translation="AYIIYTSGTTGAPKGVIVT"
     CDS_motif       1997..2086
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17705_0008"
                     /evalue="9.50E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="MOE80_RS17705"
                     /protein_end="694"
                     /protein_start="664"
                     /score="46.7"
                     /tool="antismash"
                     /translation="PIGVAGELCISGAGVAKGYHNKPDLTQMKF"
     CDS_motif       2171..2233
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17705_0009"
                     /evalue="2.80E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="MOE80_RS17705"
                     /protein_end="743"
                     /protein_start="722"
                     /score="29.2"
                     /tool="antismash"
                     /translation="LGRMDYQVKINGYRIETEEIE"
     CDS_motif       2330..2461
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17705_0010"
                     /evalue="6.60E+00"
                     /label="C2_LCL_024-062"
                     /locus_tag="MOE80_RS17705"
                     /protein_end="819"
                     /protein_start="775"
                     /score="-0.7"
                     /tool="antismash"
                     /translation="SDVNTNTLRAALTKELPAYMIPAHLIPIEKLPLTLNGKLDKNAL"
     aSDomain        2519..2710
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE80_RS17705_PCP.1"
                     /evalue="9.80E-23"
                     /label="MOE80_RS17705_PCP.1"
                     /locus_tag="MOE80_RS17705"
                     /protein_end="902"
                     /protein_start="838"
                     /score="72.1"
                     /tool="antismash"
                     /translation="KTIAEIWEDVLSIARVGIHDSFFELGGDSIKALQVAARLAAEGWS
                     MTIRDLFRYPTIQELSGHI"
     aSDomain        2747..3679
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE80_RS17705_Epimerization.1"
                     /evalue="5.80E-144"
                     /label="MOE80_RS17705_Epimerization.1"
                     /locus_tag="MOE80_RS17705"
                     /protein_end="1225"
                     /protein_start="914"
                     /score="472.6"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLVIDG"
                     /tool="antismash"
                     /translation="EGEADLAPIQRRFFGQVHAFHYHYNQSVILFSEKGFNTNALRRAL
                     RKITEHHDAIRMVFQRNQNGHVVQYNRGMNHNDHELFGLHIADWTKESLERTQFDEKLA
                     AEEIGIQSKMNVQKGPLLQAGLFKTAEGDHLLIALHHLVIDGVSWRILLEDLAAAYQQA
                     LEKQEIQLPPKTDSYLSYANGLAQIAENKQLLAEKSYWQSILDAHTAFLPKDTENVPGR
                     LQMNSDTAAFVLSGDWTEKLLFETQQAYGTNANELLLTALGMALSEWTGHDQIVISTEG
                     HGREGHVPNIDISRTVGWFTSIYPILLDMG"
     CDS_motif       2852..2923
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17705_0011"
                     /evalue="1.60E-04"
                     /label="C2_LCL_024-062"
                     /locus_tag="MOE80_RS17705"
                     /protein_end="973"
                     /protein_start="949"
                     /score="14.1"
                     /tool="antismash"
                     /translation="FNTNALRRALRKITEHHDAIRMVF"
     CDS_motif       3149..3214
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17705_0012"
                     /evalue="2.80E-11"
                     /label="NRPS-E2"
                     /locus_tag="MOE80_RS17705"
                     /protein_end="1070"
                     /protein_start="1048"
                     /score="35.5"
                     /tool="antismash"
                     /translation="LLIALHHLVIDGVSWRILLEDL"
     CDS_motif       3509..3556
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17705_0013"
                     /evalue="1.60E+00"
                     /label="Cy4"
                     /locus_tag="MOE80_RS17705"
                     /protein_end="1184"
                     /protein_start="1168"
                     /score="2.2"
                     /tool="antismash"
                     /translation="NELLLTALGMALSEWT"
     CDS_motif       3620..3670
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17705_0014"
                     /evalue="5.00E-09"
                     /label="NRPS-E5"
                     /locus_tag="MOE80_RS17705"
                     /protein_end="1222"
                     /protein_start="1205"
                     /score="28.1"
                     /tool="antismash"
                     /translation="DISRTVGWFTSIYPILL"
     aSDomain        3704..4138
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE80_RS17705_TIGR01720.1"
                     /evalue="6.90E-46"
                     /label="MOE80_RS17705_TIGR01720.1"
                     /locus_tag="MOE80_RS17705"
                     /protein_end="1378"
                     /protein_start="1233"
                     /score="147.8"
                     /tool="antismash"
                     /translation="LAYRIKTTKDMLRRVPNKGTGYGLLTHIGELPHKEPEVSFNYLGQ
                     FSEEKEAETFQLSYYQPRYEIAGEREREYELDINALITDGRLQVKAVYTQVFNQHSIEC
                     FMDRFHRHLIEMIEHCSQKKIREKTLSDFSNKELTLSALSS"
     CDS_motif       3725..3784
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17705_0015"
                     /evalue="1.00E-08"
                     /label="NRPS-E6"
                     /locus_tag="MOE80_RS17705"
                     /protein_end="1260"
                     /protein_start="1240"
                     /score="27.4"
                     /tool="antismash"
                     /translation="TKDMLRRVPNKGTGYGLLTH"
     aSDomain        4187..4270
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE80_RS17710_NRPS-COM_Nterm.1"
                     /evalue="7.40E-16"
                     /label="MOE80_RS17710_NRPS-COM_Nterm.1"
                     /locus_tag="MOE80_RS17710"
                     /protein_end="28"
                     /protein_start="0"
                     /score="49.1"
                     /tool="antismash"
                     /translation="MAQAAQIQDIYPLSHMQEGMLFHSLMDV"
     gene            4187..11869
                     /locus_tag="MOE80_RS17710"
                     /old_locus_tag="MOE80_17660"
     CDS             4187..11869
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (0-28). E-value: 7.4e-16.
                     Score: 49.1. Matches aSDomain:
                     nrpspksdomains_MOE80_RS17710_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (7-309). E-value:
                     2.1e-110. Score: 360.5. Matches aSDomain:
                     nrpspksdomains_MOE80_RS17710_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (474-865). E-value:
                     1.2e-110. Score: 361.9. Matches aSDomain:
                     nrpspksdomains_MOE80_RS17710_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (970-1036). E-value: 3e-22. Score:
                     70.6. Matches aSDomain: nrpspksdomains_MOE80_RS17710_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1054-1341). E-value:
                     8.3e-105. Score: 342.0. Matches aSDomain:
                     nrpspksdomains_MOE80_RS17710_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1505-1903). E-value:
                     6.1e-118. Score: 385.9. Matches aSDomain:
                     nrpspksdomains_MOE80_RS17710_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2011-2078). E-value: 1.8e-20.
                     Score: 64.9. Matches aSDomain:
                     nrpspksdomains_MOE80_RS17710_PCP.2"
                     /NRPS_PKS="Domain: Epimerization (2088-2393). E-value:
                     3.6e-152. Score: 499.8. Matches aSDomain:
                     nrpspksdomains_MOE80_RS17710_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (2403-2553). E-value: 2.2e-52.
                     Score: 168.9. Matches aSDomain:
                     nrpspksdomains_MOE80_RS17710_TIGR01720.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389715.1"
                     /locus_tag="MOE80_RS17710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE80_17660"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_268399488.1"
                     /sec_met_domain="Condensation (E-value: 3.1e-95, bitscore:
                     306.3, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.3e-127, bitscore:
                     413.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 7.1e-18, bitscore:
                     52.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQAAQIQDIYPLSHMQEGMLFHSLMDVSSKAYVEQTSFTITGNL
                     CIDSFQKSLNLLVSRYDIFRTIFIKEVQDLTGPQQVVLSNRELTVYREDFSHLADHEQQ
                     ALIDAFMTKDREKGFNLQKDPLMRLALFDRGNSQYTCVWTHHHIIMDGWCLGIILKEFF
                     SMYDSLKNNSPVRLGSTVPYSRYIEWLGEQDQEETAAYWSEYLKEYGNTASIPRINPRP
                     ADGDYKADQISFSLAPEMVEKLTEAAQNWGVTLNTLFMSMWGVLLHRYNATDDAVFGSV
                     ISGRPSAIDGIESMVGLFINTIPVRIRSAEGMTFSSLAKAVQEDILASEQHGYYPLYEI
                     QNHSPLKQGLIDHIFVFENYPVQLDQALSIESEDEENALKLGDISMSEQTNYDFNIVIV
                     PGESFYIKFSYNAAVYEREEMLRIQRHLKQALDCILAHPDIAVSDINIVPPEEQQVIQL
                     FNETERPYVNKTISQLFEEQARKTPEAAALKLGDDCWTYRQLNIRANQIAHALIEKGVG
                     SGDIVAVMMNRSMEMPAALLGIWKAGGAYMPLDPNFPEERLSFLLKDSQAAQLLIEENL
                     MSFIPPHYKGNMIMIEHTESHQTAAPDVPLGDLAYLIYTSGTTGRPKGVLVNHQGIANT
                     LQWRREEYGMTEQDISLHLFSYVFDGCVTSLFTPLISGACVLLTTDDEAKDVLALKRKI
                     ARYKVSHMIIVPSLYRVLLEVMTADDAKSLRIVTFAGEAVTPDLLEMSEKICPSAELAN
                     EYGPTENSVATTILRQLNEKERITIGHPIANTKVFVLHGNQMQPIGAAGELCISGTGLA
                     RGYYKQPELTEKAFSDHPFLEGERLYRTGDAGRFLPDGTIEYIGRFDDQVKIRGYRIEL
                     KEIETVLRQAPGVKEAAVLARDVSAEEKELVAYIVLEKGNNLPDLHRLLAGTLPPYMIP
                     ASFINISRMPLTSSGKLDRSALPEPENNASLTYMPPRTLIEADLAHIWGDVLNKQQIGI
                     RDDFFQLGGQSLKAAALVSRIHKKLNIELPISEVFSNPTVESMAVKLMSLKEHAFTQID
                     PADQRDVYPLSFSQKRLYALHQLADDSTGYNMPAVLELRGNLDRQRLRSVLTELVNRHE
                     ALRTVFVLDRGEPVQIIHPEMAFDLKELEMESEQMLESAIESFIKPFDLLSGPLFRACV
                     ITMGNNRGFLLLDMHHIIADGVSMRTLVQEFTDLYCEKELPALNLHYKDFAVWQQEKYP
                     KELYKKQEAYWLDQLGGSLPVLELPLDKTRPRLPDFSGGTIEVNIDKDTADELHRLMVE
                     TGTTLYMILLAVYSILLSKLSGQEDIVVGSPAAGRLHADLERVIGMFVNTLAMRSQPEG
                     HKTFSSYLQDIRHLALTAYEHQDYPFEELADKLDTHREVNRNPLFDAMLVLQSSEDFQF
                     EVPGLSISSVTAKHDISKFDLTLHAEEHSGGIHCRFEYSTALFEEETIARWASHFIELV
                     KSVTADTKMRISEMQLLPAAERNLLLEKMGQYAAYPRNENIVSLFEKQAAEHPEHLAVV
                     YGHSKLTYRDLNEKAERTAAMLIKQGVRTGDIVGLMLDRSPDMIIGILSILKAGGAYLP
                     IDPEYPQERISFMLNDSGAEMLLTERGQNKPADYNGPIMYIDEGDSDSIPDDLNIQETL
                     SDQPAYVIYTSGTTGQPKGVIVEHRNVISLLKHQNLPFKFGHEDVWTFFHSYCFDFSVW
                     EMFGALLNGSTLVVVSKETARDPHAFRLLLKKERVTVLNQTPTAFYGLMHEDQNHTDRL
                     NIRYVIFGGEALQPGMLQSWNKKYPHTDLINMYGITETTVHVTFKKLSAADIAKNKSNI
                     GRPLSTLQAYVMDAHMNLQPIGVPGEMYIGGEGVARGYLNRDELTADRFVPNPYLPGDR
                     LYRTGDLAKRLSNGELEYLGRIDDQVKVRGHRIELGEIQAALLQLPAIKEAAVITRTDE
                     KGQAAVYAYIVTKDQQAANASEIRTSLKTMLPDFMLPARLIQIDSIPLTVNGKLDQKAL
                     PEPDKHGYIADDIRPRNEIEKVIAEIWEELLDVEELGVSANFFELGGDSIKALQVCARL
                     KQRGFETTVREMFEHQTLGELSARVRKAVHVIDQGPVEGEITWTPIQQWFFSQSLEINH
                     FNQSVMLYRTERFDETALKKVLKSLVTHHDALRIVCRYEDGRSVQINRGIDLPDKELYA
                     LELFDVKDNLTEAHNRIKEAASQMQEHLRLETGPLLHAGLFRTENGDHLFLTIHHLVVD
                     AVSWRILFEDFSTAYKQEVSGETIKLPQKTDSYLTYSQRIADYSKSRQIQREEAYWDER
                     ENRHIQPIPKDNEAAPNTFKDTEVIDFNLSRHHTELLLTAANKAYSTEMNDILLTALGL
                     ALQQWTGYDQFKISMEGHGRESYLEDIDISRTVGWFTSIYPVWLDMSNSDHKNKDERLG
                     HLIKQTKDMLHRIPHKGAGYGVLKYTNKKWGSEKGSPDISFNYLGQFDQDIQSKAFEVS
                     DIKPGNEISPEWERPYALDISGAVSSGCLNMHMIYNRLQFEKKTIQTFAEHFKQTLENI
                     IEHCTGKENREWSASDFTDEDLTLDELSEIMGAVNKL"
     aSDomain        4208..5113
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE80_RS17710_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="2.10E-110"
                     /label="MOE80_RS17710_Condensation_DCL.1"
                     /locus_tag="MOE80_RS17710"
                     /protein_end="309"
                     /protein_start="7"
                     /score="360.5"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIIMDG"
                     /tool="antismash"
                     /translation="QDIYPLSHMQEGMLFHSLMDVSSKAYVEQTSFTITGNLCIDSFQK
                     SLNLLVSRYDIFRTIFIKEVQDLTGPQQVVLSNRELTVYREDFSHLADHEQQALIDAFM
                     TKDREKGFNLQKDPLMRLALFDRGNSQYTCVWTHHHIIMDGWCLGIILKEFFSMYDSLK
                     NNSPVRLGSTVPYSRYIEWLGEQDQEETAAYWSEYLKEYGNTASIPRINPRPADGDYKA
                     DQISFSLAPEMVEKLTEAAQNWGVTLNTLFMSMWGVLLHRYNATDDAVFGSVISGRPSA
                     IDGIESMVGLFINTIPVRIRS"
     aSModule        4208..7294
                     /complete
                     /domains="nrpspksdomains_MOE80_RS17710_Condensation_DCL.1"
                     /domains="nrpspksdomains_MOE80_RS17710_AMP-binding.1"
                     /domains="nrpspksdomains_MOE80_RS17710_PCP.1"
                     /locus_tags="MOE80_RS17710"
                     /monomer_pairings="Tyr -> Tyr"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       4217..4258
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17710_0001"
                     /evalue="9.00E-05"
                     /label="C1_DCL_004-017"
                     /locus_tag="MOE80_RS17710"
                     /protein_end="24"
                     /protein_start="10"
                     /score="14.5"
                     /tool="antismash"
                     /translation="YPLSHMQEGMLFHS"
     CDS_motif       4280..4393
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17710_0002"
                     /evalue="1.70E-14"
                     /label="C2_DCL_024-062"
                     /locus_tag="MOE80_RS17710"
                     /protein_end="69"
                     /protein_start="31"
                     /score="46.1"
                     /tool="antismash"
                     /translation="AYVEQTSFTITGNLCIDSFQKSLNLLVSRYDIFRTIFI"
     CDS_motif       4619..4684
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17710_0003"
                     /evalue="2.50E-11"
                     /label="C3_DCL_135-156"
                     /locus_tag="MOE80_RS17710"
                     /protein_end="166"
                     /protein_start="144"
                     /score="35.9"
                     /tool="antismash"
                     /translation="HHHIIMDGWCLGIILKEFFSMY"
     CDS_motif       5009..5104
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17710_0004"
                     /evalue="4.20E-19"
                     /label="C5_DCL_263-294"
                     /locus_tag="MOE80_RS17710"
                     /protein_end="306"
                     /protein_start="274"
                     /score="61.0"
                     /tool="antismash"
                     /translation="DAVFGSVISGRPSAIDGIESMVGLFINTIPVR"
     CDS_motif       5153..5269
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17710_0005"
                     /evalue="6.20E-20"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="MOE80_RS17710"
                     /protein_end="361"
                     /protein_start="322"
                     /score="63.7"
                     /tool="antismash"
                     /translation="QEDILASEQHGYYPLYEIQNHSPLKQGLIDHIFVFENYP"
     aSDomain        5609..6781
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE80_RS17710_AMP-binding.1"
                     /evalue="1.20E-110"
                     /label="MOE80_RS17710_AMP-binding.1"
                     /locus_tag="MOE80_RS17710"
                     /protein_end="865"
                     /protein_start="474"
                     /score="361.9"
                     /specificity="substrate consensus: Tyr"
                     /tool="antismash"
                     /translation="FEEQARKTPEAAALKLGDDCWTYRQLNIRANQIAHALIEKGVGSG
                     DIVAVMMNRSMEMPAALLGIWKAGGAYMPLDPNFPEERLSFLLKDSQAAQLLIEENLMS
                     FIPPHYKGNMIMIEHTESHQTAAPDVPLGDLAYLIYTSGTTGRPKGVLVNHQGIANTLQ
                     WRREEYGMTEQDISLHLFSYVFDGCVTSLFTPLISGACVLLTTDDEAKDVLALKRKIAR
                     YKVSHMIIVPSLYRVLLEVMTADDAKSLRIVTFAGEAVTPDLLEMSEKICPSAELANEY
                     GPTENSVATTILRQLNEKERITIGHPIANTKVFVLHGNQMQPIGAAGELCISGTGLARG
                     YYKQPELTEKAFSDHPFLEGERLYRTGDAGRFLPDGTIEYIGRFDDQVKIR"
     CDS_motif       5795..5836
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17710_0006"
                     /evalue="6.80E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="MOE80_RS17710"
                     /protein_end="550"
                     /protein_start="536"
                     /score="16.1"
                     /tool="antismash"
                     /translation="LGIWKAGGAYMPLD"
     CDS_motif       6014..6073
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17710_0007"
                     /evalue="2.20E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="MOE80_RS17710"
                     /protein_end="629"
                     /protein_start="609"
                     /score="29.3"
                     /tool="antismash"
                     /translation="AYLIYTSGTTGRPKGVLVNH"
     CDS_motif       6446..6478
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17710_0008"
                     /evalue="1.20E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="MOE80_RS17710"
                     /protein_end="764"
                     /protein_start="753"
                     /score="5.7"
                     /tool="antismash"
                     /translation="EYGPTENSVAT"
     CDS_motif       6575..6664
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17710_0009"
                     /evalue="1.40E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="MOE80_RS17710"
                     /protein_end="826"
                     /protein_start="796"
                     /score="46.1"
                     /tool="antismash"
                     /translation="PIGAAGELCISGTGLARGYYKQPELTEKAF"
     CDS_motif       6746..6811
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17710_0010"
                     /evalue="2.70E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="MOE80_RS17710"
                     /protein_end="875"
                     /protein_start="853"
                     /score="35.4"
                     /tool="antismash"
                     /translation="YIGRFDDQVKIRGYRIELKEIE"
     aSDomain        7097..7294
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE80_RS17710_PCP.1"
                     /evalue="3.00E-22"
                     /label="MOE80_RS17710_PCP.1"
                     /locus_tag="MOE80_RS17710"
                     /protein_end="1036"
                     /protein_start="970"
                     /score="70.6"
                     /tool="antismash"
                     /translation="EADLAHIWGDVLNKQQIGIRDDFFQLGGQSLKAAALVSRIHKKLN
                     IELPISEVFSNPTVESMAVKL"
     aSDomain        7349..8209
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE80_RS17710_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="8.30E-105"
                     /label="MOE80_RS17710_Condensation_LCL.1"
                     /locus_tag="MOE80_RS17710"
                     /protein_end="1341"
                     /protein_start="1054"
                     /score="342.0"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIIADG"
                     /tool="antismash"
                     /translation="VYPLSFSQKRLYALHQLADDSTGYNMPAVLELRGNLDRQRLRSVL
                     TELVNRHEALRTVFVLDRGEPVQIIHPEMAFDLKELEMESEQMLESAIESFIKPFDLLS
                     GPLFRACVITMGNNRGFLLLDMHHIIADGVSMRTLVQEFTDLYCEKELPALNLHYKDFA
                     VWQQEKYPKELYKKQEAYWLDQLGGSLPVLELPLDKTRPRLPDFSGGTIEVNIDKDTAD
                     ELHRLMVETGTTLYMILLAVYSILLSKLSGQEDIVVGSPAAGRLHADLERVIGMFVNTL
                     AMRSQP"
     aSModule        7349..11845
                     /complete
                     /domains="nrpspksdomains_MOE80_RS17710_Condensation_LCL.1"
                     /domains="nrpspksdomains_MOE80_RS17710_AMP-binding.2"
                     /domains="nrpspksdomains_MOE80_RS17710_PCP.2"
                     /domains="nrpspksdomains_MOE80_RS17710_Epimerization.1"
                     /domains="nrpspksdomains_MOE80_RS17710_TIGR01720.1"
                     /locus_tags="MOE80_RS17710"
                     /monomer_pairings="Thr -> D-Thr"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       7418..7528
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17710_0011"
                     /evalue="2.80E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="MOE80_RS17710"
                     /protein_end="1114"
                     /protein_start="1077"
                     /score="55.1"
                     /tool="antismash"
                     /translation="YNMPAVLELRGNLDRQRLRSVLTELVNRHEALRTVFV"
     CDS_motif       7724..7789
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17710_0012"
                     /evalue="1.60E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="MOE80_RS17710"
                     /protein_end="1201"
                     /protein_start="1179"
                     /score="30.2"
                     /tool="antismash"
                     /translation="MHHIIADGVSMRTLVQEFTDLY"
     CDS_motif       7820..7855
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17710_0013"
                     /evalue="5.60E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="MOE80_RS17710"
                     /protein_end="1223"
                     /protein_start="1211"
                     /score="12.6"
                     /tool="antismash"
                     /translation="HYKDFAVWQQEK"
     CDS_motif       8111..8200
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17710_0014"
                     /evalue="7.40E-16"
                     /label="C5_LCL_267-296"
                     /locus_tag="MOE80_RS17710"
                     /protein_end="1338"
                     /protein_start="1308"
                     /score="50.5"
                     /tool="antismash"
                     /translation="DIVVGSPAAGRLHADLERVIGMFVNTLAMR"
     CDS_motif       8255..8368
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17710_0015"
                     /evalue="2.60E-14"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="MOE80_RS17710"
                     /protein_end="1394"
                     /protein_start="1356"
                     /score="45.5"
                     /tool="antismash"
                     /translation="LALTAYEHQDYPFEELADKLDTHREVNRNPLFDAMLVL"
     aSDomain        8702..9895
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE80_RS17710_AMP-binding.2"
                     /evalue="6.10E-118"
                     /label="MOE80_RS17710_AMP-binding.2"
                     /locus_tag="MOE80_RS17710"
                     /protein_end="1903"
                     /protein_start="1505"
                     /score="385.9"
                     /specificity="substrate consensus: Thr"
                     /tool="antismash"
                     /translation="FEKQAAEHPEHLAVVYGHSKLTYRDLNEKAERTAAMLIKQGVRTG
                     DIVGLMLDRSPDMIIGILSILKAGGAYLPIDPEYPQERISFMLNDSGAEMLLTERGQNK
                     PADYNGPIMYIDEGDSDSIPDDLNIQETLSDQPAYVIYTSGTTGQPKGVIVEHRNVISL
                     LKHQNLPFKFGHEDVWTFFHSYCFDFSVWEMFGALLNGSTLVVVSKETARDPHAFRLLL
                     KKERVTVLNQTPTAFYGLMHEDQNHTDRLNIRYVIFGGEALQPGMLQSWNKKYPHTDLI
                     NMYGITETTVHVTFKKLSAADIAKNKSNIGRPLSTLQAYVMDAHMNLQPIGVPGEMYIG
                     GEGVARGYLNRDELTADRFVPNPYLPGDRLYRTGDLAKRLSNGELEYLGRIDDQVKVR"
     CDS_motif       8888..8929
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17710_0016"
                     /evalue="1.70E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="MOE80_RS17710"
                     /protein_end="1581"
                     /protein_start="1567"
                     /score="15.0"
                     /tool="antismash"
                     /translation="LSILKAGGAYLPID"
     CDS_motif       9113..9172
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17710_0017"
                     /evalue="4.50E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="MOE80_RS17710"
                     /protein_end="1662"
                     /protein_start="1642"
                     /score="31.4"
                     /tool="antismash"
                     /translation="AYVIYTSGTTGQPKGVIVEH"
     CDS_motif       9551..9574
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17710_0018"
                     /evalue="2.50E+00"
                     /label="NRPS-A_a5"
                     /locus_tag="MOE80_RS17710"
                     /protein_end="1796"
                     /protein_start="1788"
                     /score="2.0"
                     /tool="antismash"
                     /translation="YGITETTV"
     CDS_motif       9689..9778
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17710_0019"
                     /evalue="2.30E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="MOE80_RS17710"
                     /protein_end="1864"
                     /protein_start="1834"
                     /score="55.0"
                     /tool="antismash"
                     /translation="PIGVPGEMYIGGEGVARGYLNRDELTADRF"
     CDS_motif       9860..9925
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17710_0020"
                     /evalue="6.90E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="MOE80_RS17710"
                     /protein_end="1913"
                     /protein_start="1891"
                     /score="37.3"
                     /tool="antismash"
                     /translation="YLGRIDDQVKVRGHRIELGEIQ"
     aSDomain        10220..10420
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE80_RS17710_PCP.2"
                     /evalue="1.80E-20"
                     /label="MOE80_RS17710_PCP.2"
                     /locus_tag="MOE80_RS17710"
                     /protein_end="2078"
                     /protein_start="2011"
                     /score="64.9"
                     /tool="antismash"
                     /translation="EKVIAEIWEELLDVEELGVSANFFELGGDSIKALQVCARLKQRGF
                     ETTVREMFEHQTLGELSARVRK"
     aSDomain        10451..11365
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE80_RS17710_Epimerization.1"
                     /evalue="3.60E-152"
                     /label="MOE80_RS17710_Epimerization.1"
                     /locus_tag="MOE80_RS17710"
                     /protein_end="2393"
                     /protein_start="2088"
                     /score="499.8"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLVVDA"
                     /tool="antismash"
                     /translation="EGEITWTPIQQWFFSQSLEINHFNQSVMLYRTERFDETALKKVLK
                     SLVTHHDALRIVCRYEDGRSVQINRGIDLPDKELYALELFDVKDNLTEAHNRIKEAASQ
                     MQEHLRLETGPLLHAGLFRTENGDHLFLTIHHLVVDAVSWRILFEDFSTAYKQEVSGET
                     IKLPQKTDSYLTYSQRIADYSKSRQIQREEAYWDERENRHIQPIPKDNEAAPNTFKDTE
                     VIDFNLSRHHTELLLTAANKAYSTEMNDILLTALGLALQQWTGYDQFKISMEGHGRESY
                     LEDIDISRTVGWFTSIYPVWLDMS"
     CDS_motif       10466..10492
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17710_0021"
                     /evalue="2.90E-03"
                     /label="NRPS-E1"
                     /locus_tag="MOE80_RS17710"
                     /protein_end="2102"
                     /protein_start="2093"
                     /score="10.8"
                     /tool="antismash"
                     /translation="WTPIQQWFF"
     CDS_motif       10550..10615
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17710_0022"
                     /evalue="8.70E-03"
                     /label="C2_LCL_024-062"
                     /locus_tag="MOE80_RS17710"
                     /protein_end="2143"
                     /protein_start="2121"
                     /score="8.5"
                     /tool="antismash"
                     /translation="RFDETALKKVLKSLVTHHDALR"
     CDS_motif       10838..10903
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17710_0023"
                     /evalue="1.60E-11"
                     /label="NRPS-E2"
                     /locus_tag="MOE80_RS17710"
                     /protein_end="2239"
                     /protein_start="2217"
                     /score="36.3"
                     /tool="antismash"
                     /translation="LFLTIHHLVVDAVSWRILFEDF"
     CDS_motif       11306..11356
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17710_0024"
                     /evalue="5.10E-09"
                     /label="NRPS-E5"
                     /locus_tag="MOE80_RS17710"
                     /protein_end="2390"
                     /protein_start="2373"
                     /score="28.0"
                     /tool="antismash"
                     /translation="DISRTVGWFTSIYPVWL"
     aSDomain        11396..11845
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE80_RS17710_TIGR01720.1"
                     /evalue="2.20E-52"
                     /label="MOE80_RS17710_TIGR01720.1"
                     /locus_tag="MOE80_RS17710"
                     /protein_end="2553"
                     /protein_start="2403"
                     /score="168.9"
                     /tool="antismash"
                     /translation="LGHLIKQTKDMLHRIPHKGAGYGVLKYTNKKWGSEKGSPDISFNY
                     LGQFDQDIQSKAFEVSDIKPGNEISPEWERPYALDISGAVSSGCLNMHMIYNRLQFEKK
                     TIQTFAEHFKQTLENIIEHCTGKENREWSASDFTDEDLTLDELSEI"
     CDS_motif       11417..11476
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17710_0025"
                     /evalue="5.20E-08"
                     /label="NRPS-E6"
                     /locus_tag="MOE80_RS17710"
                     /protein_end="2430"
                     /protein_start="2410"
                     /score="25.2"
                     /tool="antismash"
                     /translation="TKDMLHRIPHKGAGYGVLKY"
     gene            11889..>14531
                     /locus_tag="MOE80_RS17715"
                     /old_locus_tag="MOE80_17665"
     CDS             11889..>14531
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (2-30). E-value: 2.1e-16.
                     Score: 50.9. Matches aSDomain:
                     nrpspksdomains_MOE80_RS17715_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (7-305). E-value:
                     1.3e-117. Score: 384.2. Matches aSDomain:
                     nrpspksdomains_MOE80_RS17715_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (469-870). E-value:
                     3.8e-113. Score: 370.1. Matches aSDomain:
                     nrpspksdomains_MOE80_RS17715_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389714.1"
                     /locus_tag="MOE80_RS17715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE80_17665"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_268399490.1"
                     /sec_met_domain="Condensation (E-value: 4.1e-93, bitscore:
                     299.3, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 6.1e-119, bitscore:
                     384.9, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQQPEIQDIYPLSFMQEGMLFHSLYDEQSRAYFEQASFTIHGQL
                     DLERFQKSMDAVFERYEIFRTAFIYKNVAKPRQVVLKHRHCHVHFEDISHLNERDKEHC
                     TEAFKEQDKSRGFDLQTDVLMRISILKWAPNRYVCIWSHHHILMDGWCLGIVIKDFLHI
                     YQALGKGQLPNLHPVQPYGTYIKWLMRQDREEAAEYWKKRLQHFEKATPLPKRTDQIPD
                     GTLEQITFTISEKETSELQKIAAASGATLNTVFQALWGIMLQKFNRCGDAVFGSVISGR
                     PSELRDVENMVGLFINTIPIRVQSDSLSFSDLVSRMQKDMTEAEAYSYFPLYDIQAQSA
                     LKQELIDHIIVFENTPTQQEIEGLNQAGSFDFSVKDFEMEEVTNYSCSVKVIPGRTLYV
                     RIHFYTGAYQPNMMSEIKDYLQHMVSDVISDPSLPVSKMTLLDENKTRKIVSQNNGAVS
                     VSPEAPTLHGLFERQAAVTPERPAIRFSGGSLTYAELDMYASRLAAGLAARGVTKESIV
                     GVLSERSPEMLIAVLAVLKAGGAYLPLDPAYPKERLSYMLKDSGAALLLAQPGCSAPSF
                     SGEMLEVDMASLASEKAENDVFTPADGGSLAYVIYTSGSTGKPKGVAVEHRQAVSFLTG
                     MQRQFPLQEDDIVMVKTSFSFDASVWQLFWWSLSGASAYLLPPGWEKDPALIVKAIHQE
                     KVTTAHFIPAMLNSFLDQAEMKALGDGTSLKRVFAGGEPLAPHVAARFASLLPQVSLIH
                     GYGPTEATVDAAFYVLDPERDRDRLRIPIGKPVPGARLYVLDPHLAVQPCGVAGELYIA
                     GSGVARGYLNRQALTEERFLEDPFYPGERVYKTGDLARWLPDGNIEFLGRTDDQVKIRG
                     YRIEPGEIEA"
     aSDomain        11895..11978
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE80_RS17715_NRPS-COM_Nterm.1"
                     /evalue="2.10E-16"
                     /label="MOE80_RS17715_NRPS-COM_Nterm.1"
                     /locus_tag="MOE80_RS17715"
                     /protein_end="30"
                     /protein_start="2"
                     /score="50.9"
                     /tool="antismash"
                     /translation="QQPEIQDIYPLSFMQEGMLFHSLYDEQS"
     aSDomain        11910..12803
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE80_RS17715_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="1.30E-117"
                     /label="MOE80_RS17715_Condensation_DCL.1"
                     /locus_tag="MOE80_RS17715"
                     /protein_end="305"
                     /protein_start="7"
                     /score="384.2"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHILMDG"
                     /tool="antismash"
                     /translation="QDIYPLSFMQEGMLFHSLYDEQSRAYFEQASFTIHGQLDLERFQK
                     SMDAVFERYEIFRTAFIYKNVAKPRQVVLKHRHCHVHFEDISHLNERDKEHCTEAFKEQ
                     DKSRGFDLQTDVLMRISILKWAPNRYVCIWSHHHILMDGWCLGIVIKDFLHIYQALGKG
                     QLPNLHPVQPYGTYIKWLMRQDREEAAEYWKKRLQHFEKATPLPKRTDQIPDGTLEQIT
                     FTISEKETSELQKIAAASGATLNTVFQALWGIMLQKFNRCGDAVFGSVISGRPSELRDV
                     ENMVGLFINTIPIRVQS"
     aSModule        11910..14498
                     /domains="nrpspksdomains_MOE80_RS17715_Condensation_DCL.1"
                     /domains="nrpspksdomains_MOE80_RS17715_AMP-binding.1"
                     /incomplete
                     /locus_tags="MOE80_RS17715"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       11919..11960
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17715_0001"
                     /evalue="5.20E-05"
                     /label="C1_DCL_004-017"
                     /locus_tag="MOE80_RS17715"
                     /protein_end="24"
                     /protein_start="10"
                     /score="15.2"
                     /tool="antismash"
                     /translation="YPLSFMQEGMLFHS"
     CDS_motif       11982..12098
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17715_0002"
                     /evalue="3.80E-18"
                     /label="C2_DCL_024-062"
                     /locus_tag="MOE80_RS17715"
                     /protein_end="70"
                     /protein_start="31"
                     /score="57.8"
                     /tool="antismash"
                     /translation="AYFEQASFTIHGQLDLERFQKSMDAVFERYEIFRTAFIY"
     CDS_motif       12315..12380
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17715_0003"
                     /evalue="5.70E-11"
                     /label="C3_DCL_135-156"
                     /locus_tag="MOE80_RS17715"
                     /protein_end="164"
                     /protein_start="142"
                     /score="34.8"
                     /tool="antismash"
                     /translation="HHHILMDGWCLGIVIKDFLHIY"
     CDS_motif       12426..12464
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17715_0004"
                     /evalue="6.80E-03"
                     /label="C4_DCL_171-183"
                     /locus_tag="MOE80_RS17715"
                     /protein_end="192"
                     /protein_start="179"
                     /score="9.4"
                     /tool="antismash"
                     /translation="PYGTYIKWLMRQD"
     CDS_motif       12699..12794
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17715_0005"
                     /evalue="1.50E-19"
                     /label="C5_DCL_263-294"
                     /locus_tag="MOE80_RS17715"
                     /protein_end="302"
                     /protein_start="270"
                     /score="62.3"
                     /tool="antismash"
                     /translation="DAVFGSVISGRPSELRDVENMVGLFINTIPIR"
     CDS_motif       12840..12956
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17715_0006"
                     /evalue="1.00E-18"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="MOE80_RS17715"
                     /protein_end="356"
                     /protein_start="317"
                     /score="59.7"
                     /tool="antismash"
                     /translation="QKDMTEAEAYSYFPLYDIQAQSALKQELIDHIIVFENTP"
     aSDomain        13296..14498
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE80_RS17715_AMP-binding.1"
                     /evalue="3.80E-113"
                     /label="MOE80_RS17715_AMP-binding.1"
                     /locus_tag="MOE80_RS17715"
                     /protein_end="870"
                     /protein_start="469"
                     /score="370.1"
                     /specificity="substrate consensus: Glu"
                     /tool="antismash"
                     /translation="FERQAAVTPERPAIRFSGGSLTYAELDMYASRLAAGLAARGVTKE
                     SIVGVLSERSPEMLIAVLAVLKAGGAYLPLDPAYPKERLSYMLKDSGAALLLAQPGCSA
                     PSFSGEMLEVDMASLASEKAENDVFTPADGGSLAYVIYTSGSTGKPKGVAVEHRQAVSF
                     LTGMQRQFPLQEDDIVMVKTSFSFDASVWQLFWWSLSGASAYLLPPGWEKDPALIVKAI
                     HQEKVTTAHFIPAMLNSFLDQAEMKALGDGTSLKRVFAGGEPLAPHVAARFASLLPQVS
                     LIHGYGPTEATVDAAFYVLDPERDRDRLRIPIGKPVPGARLYVLDPHLAVQPCGVAGEL
                     YIAGSGVARGYLNRQALTEERFLEDPFYPGERVYKTGDLARWLPDGNIEFLGRTDDQVK
                     IR"
     CDS_motif       13482..13523
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17715_0007"
                     /evalue="5.30E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="MOE80_RS17715"
                     /protein_end="545"
                     /protein_start="531"
                     /score="19.4"
                     /tool="antismash"
                     /translation="LAVLKAGGAYLPLD"
     CDS_motif       13707..13766
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17715_0008"
                     /evalue="2.30E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="MOE80_RS17715"
                     /protein_end="626"
                     /protein_start="606"
                     /score="35.3"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGKPKGVAVEH"
     CDS_motif       14292..14381
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17715_0009"
                     /evalue="9.80E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="MOE80_RS17715"
                     /protein_end="831"
                     /protein_start="801"
                     /score="53.0"
                     /tool="antismash"
                     /translation="PCGVAGELYIAGSGVARGYLNRQALTEERF"
     CDS_motif       14463..14528
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE80_RS17715_0010"
                     /evalue="4.70E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="MOE80_RS17715"
                     /protein_end="880"
                     /protein_start="858"
                     /score="40.9"
                     /tool="antismash"
                     /translation="FLGRTDDQVKIRGYRIEPGEIE"
ORIGIN
        1 tatgcatcac attatttcag acggtgtttc cgtcaatatt ctgattcggg aattcgggga
       61 gctttacaac aaccggaccc ttccggccct tcacattcaa tataaagact acgccgtatg
      121 gcaagaagga tttaaaaaag gagacgcgta ccagacgcag gaggcgtact ggctgaagca
      181 gctcgagggc gaactgccgg tgctggatct cccggctgat catacccgcc cgccggtgcg
      241 gagcttcgcg ggtgacaagg tctcatttac gcttgatcaa gaggccgcat caggccttca
      301 taagctggca cgggaaaacg gaagcacact gtacatggtg cttctagcgg cttacacagc
      361 gttattgtcc cgcttaagcg gacaggaaga tatcatcgtc ggatcgccaa ttgccggccg
      421 gccgcacaag gatcttgagc cgatactcgg catgtttgtg aacacgctgg cgctgcggac
      481 acgcccggag ggcgggaagc cgtttgtgca gtatttgcag gaagtgcgcg agacagcatt
      541 ggaagcctac gagcatcagg attatccgtt cgaagagctc gtcgacaagc ttaaattgac
      601 gcgggatatg agccggaatc cagtttttga tgcgatgttt atccttcaaa atatggaaaa
      661 gcaggacatg gatctggaag agataaaagt ccggcccgcc aatttcgcac atcacatttc
      721 tttattcgat atcacactaa tagcaacgga aacagatgga gccatttgct gcgaattgga
      781 atttagtacg gaagtattcc tgaaagctac gattgagcgc tgggcagctc attttatcga
      841 atttctgcat gcggcacttt ctaatcctga aacaaacctt tcacaaataa acattcttag
      901 tcatcaagaa aaacaaaaga tagtctttga attcaacaaa actcaaattg aattttctca
      961 aaaagatgtt ccttttcatc gcatatttga agcgagagct gaagaaacac cagaacatat
     1021 agctgttatt gatgacgaaa cacagattag ttatcggctt ctaaacgaaa gagccaatcg
     1081 actggcacgg acgttgcaaa aaagaaaagg ggcgaagcca actgtggctg ttttagccaa
     1141 gcggtccatt gatgcaattg ttggaatcct agcagtaatg aaagctggcg gagtgtatat
     1201 cccaatcgat tcacattatc caaaagctag aattgaatac cttctccgtg atagcgaagc
     1261 agacattctt cttttgcagc aggagttgaa gcatttgatt tcaaactctt ctgaatgtga
     1321 tatatctcac atctgccttg atgatgagag ctcttatgaa gaaaacagct gcaaccttga
     1381 cttatctcct gctcctgagg atgtagcata tatcatttat acgtcaggaa ctacgggcgc
     1441 gcctaaaggc gttattgtca cctatcggaa ctttacccat gcagctcttg cttggcggca
     1501 aatttatgaa ctggatcgga agcctgtcag actgctccaa atggcgagct tttcatttga
     1561 tgtcttttca ggagatttag cgagaacatt gatcaacggc gggactctaa tcgtttgccc
     1621 agatgaaaag cggctggaac ctgctgaatt atatggaatc atgaactctc ggcgaatcac
     1681 gataatggag tcaacgccgg ctctcattat cccaattatg gagtatgtat accgtaacaa
     1741 gctcaagctt cctgacttag acatattgat tcttggttcc gacatggtga aagctcaaga
     1801 tttcaaaaca ttgacagaac gctttggcca aagcatgcgc atcatcaata gttatggcgt
     1861 cacagaagcg acgatcgatt ccagctgcta tgaaacaagg atgggagaag agtatacggg
     1921 agataacgtc ccaattggca gcccgctacc gaatgtacac atgtacgtac tcagccagac
     1981 taatcaaatt cagccgattg gcgttgccgg cgagctatgc atcagcggag caggtgttgc
     2041 gaaaggctat cataataaac ctgacttaac gcaaatgaaa tttacagaaa atccatttgt
     2101 ctccggagaa aggctgtaca gaaccggtga tcgagcctgc tggcttccaa acggaacgat
     2161 caagcttctt ggccgaatgg attatcaggt gaagataaat ggatacagaa ttgaaacaga
     2221 agaaattgaa agtgttctgc ttcaaaccgg gctggtcaga gaagctgctg ttgccgttca
     2281 gcatgataag aatggacatg ctggtttagc agcatatatt gtgccttcag acgtcaatac
     2341 gaatactctc cgtgctgctt taacaaagga gctgccggca tatatgattc ctgcgcatct
     2401 gattcctata gaaaaactgc cgctgaccct aaacggaaag ctggacaaaa acgccttgcc
     2461 ggctccaaat gatgtgttca cacgtccata tacggcacca gttaacgaca tacaaaaaac
     2521 gatagcggaa atatgggaag atgtcctgtc cattgctcga gtcggcattc acgattcctt
     2581 ttttgagctt ggcggagact caataaaagc attacaagtg gcagcacggc tggccgctga
     2641 aggctggagc atgacaatac gtgacttatt ccgttatcca acgattcagg agctaagcgg
     2701 acatatcaca ccattggcat ctcaagctga tcagggacct gcggaaggtg aagctgatct
     2761 cgccccgatt cagcgaagat ttttcggaca ggttcatgct tttcactacc attacaacca
     2821 gtccgtcata cttttcagtg aaaaaggatt caatactaat gcgcttcgtc gggcgctgcg
     2881 taaaataacc gagcatcacg atgcaattcg catggttttt caacgaaatc aaaacggcca
     2941 tgtcgttcag tataatcgcg gaatgaatca caacgatcat gaactgttcg gccttcacat
     3001 agcagactgg acaaaagaat cactggaaag gactcagttt gatgaaaaac tagccgctga
     3061 ggaaatcggc attcaaagca aaatgaatgt acaaaaaggg cctctgctgc aagcaggttt
     3121 gtttaaaacg gcagaagggg accatttgct gattgcgctt catcatcttg tgatagatgg
     3181 cgtttcttgg agaatactgc ttgaggattt agctgcagca taccagcagg ctttagaaaa
     3241 acaagagatc caattaccgc caaaaacgga ttcttatttg tcctacgcca atggtcttgc
     3301 acaaattgct gaaaacaaac aattgcttgc agaaaaatca tattggcaat caattttgga
     3361 cgctcacact gcttttctgc ctaaggacac ggaaaatgtg ccaggaagac tgcaaatgaa
     3421 cagcgataca gcggcgtttg tactatccgg ggactggact gaaaaattgc tgtttgaaac
     3481 ccagcaagcc tatggcacta atgccaacga acttttgctt acggcgttag gaatggcgct
     3541 ttctgaatgg acaggacatg accaaatcgt gattagcact gagggacacg gtagagaggg
     3601 gcatgtgcca aacattgata tttcacggac agttggatgg tttacttcca tttatcctat
     3661 tctgctggac atgggtattc ccgagccttt cgaggatcag ctcgcatacc gaattaagac
     3721 gacaaaagat atgctgagaa gggtaccgaa caaaggaact ggttacggat tgttaacaca
     3781 cataggagaa ctacctcata aagagcctga ggttagcttt aattatctcg gccaatttag
     3841 cgaagagaag gaagctgaaa cgtttcaatt atcatattac cagcctcgtt acgaaatagc
     3901 gggtgagaga gaacgagagt atgagctgga catcaatgcc ctcattacgg acggaaggct
     3961 tcaagtaaaa gcggtataca cccaagtgtt caaccaacac tcaattgagt gttttatgga
     4021 tcgttttcac aggcatctta tcgagatgat tgagcattgt tctcagaaaa aaatacgcga
     4081 aaaaacgctg agtgatttca gcaataagga attaacgttg tctgcattat ctagcatcga
     4141 agatctcgtg aaagatcttt aacttttaaa aaggtgtgtg gaattgatgg cacaagcggc
     4201 acagattcaa gatatttatc cgttatcgca catgcaggaa ggaatgctgt ttcattcact
     4261 gatggatgtc agctcaaaag cctatgtcga acagacctcg tttacgatca cagggaatct
     4321 atgcatcgac tcgtttcaaa agagcttaaa ccttcttgtt tcccggtatg atattttcag
     4381 aacgattttt attaaagaag tccaagatct tacaggtccg cagcaggtag tcctgtcaaa
     4441 ccgggaattg acagtgtata gagaagattt ttctcacctg gccgatcatg aacagcaggc
     4501 tctgatcgat gcttttatga ccaaggatcg ggaaaaagga tttaatttgc aaaaagatcc
     4561 gttaatgcgt cttgcccttt ttgatagagg caacagccaa tatacatgtg tctggacaca
     4621 tcaccatatc atcatggatg gctggtgtct aggcattatt cttaaagagt ttttcagcat
     4681 gtatgattcg ctcaaaaata actcacctgt acggcttggc agcacggtac cgtacagccg
     4741 ctatattgaa tggctcggag aacaagatca agaagagact gctgcttact ggagcgaata
     4801 tttgaaggag tacggcaata ctgcatctat cccccggata aatccccgcc cggcggacgg
     4861 ggattataaa gccgaccaga tcagcttttc tttagcaccg gaaatggttg agaaactgac
     4921 tgaggccgcc caaaattggg gagtgacatt aaacacgttg tttatgagta tgtggggcgt
     4981 gctcctccat cgatataatg ccacagatga cgcagttttt ggctccgtca tttcgggacg
     5041 cccgtcagcg attgacggta ttgaatcaat ggtcggcttg tttattaata ctatcccagt
     5101 gcgaattcga tctgcggagg gcatgacgtt ttcttcgctg gccaaagccg tgcaggagga
     5161 tattttagca tctgaacagc atgggtatta tccgctttat gaaattcaga accatagtcc
     5221 attgaagcaa gggttgatcg atcatatttt tgtctttgaa aattatcctg tacagcttga
     5281 tcaggcgtta agtattgaga gtgaagacga ggaaaatgca ctgaagcttg gtgacatttc
     5341 aatgtcggag caaaccaatt acgactttaa tatcgttatt gttccgggag aatcatttta
     5401 tatcaaattc agctacaacg cagccgttta tgaacgggag gagatgctga ggattcagag
     5461 gcatctaaaa caagctctag attgcatttt ggcacatccc gatattgccg tcagtgacat
     5521 caatatcgtc ccgccggagg agcaacaggt tatccaattg tttaacgaaa ctgagcgtcc
     5581 ttatgtgaac aaaacgatat cccaattgtt cgaggaacaa gcccgcaaaa cacctgaagc
     5641 tgctgcatta aaattgggag acgattgctg gacctatcgc caattaaata taagagccaa
     5701 tcagattgcg cacgccctga tagaaaaagg cgttggatct ggagatatcg tggctgtgat
     5761 gatgaaccgg tcaatggaaa tgcctgcagc tctacttggg atttggaaag caggcggcgc
     5821 ttatatgccg cttgatccaa atttcccaga agaacgtctt tcttttctgc tgaaggacag
     5881 tcaagcagct caattgctga tagaagaaaa ccttatgtca ttcatcccgc cgcactataa
     5941 aggaaatatg ataatgatag aacatacaga aagtcaccaa acagcagctc cagatgtgcc
     6001 gcttggtgat ctcgcctatt tgatctatac gtcgggaacg acagggcgcc ctaaaggtgt
     6061 tctagttaat catcaaggca ttgccaatac attgcaatgg agacgggaag agtatggcat
     6121 gaccgaacag gatatatccc tccatttgtt ttcatatgtg tttgacggtt gtgtgacgag
     6181 cttgtttacc ccgcttatat ccggtgcgtg cgtattgctg acaacggatg acgaagcgaa
     6241 ggatgtgcta gcccttaaac gaaaaatagc ccgttataag gtcagtcaca tgatcattgt
     6301 tccttccctg taccgggtgt tattggaagt gatgactgct gacgatgcaa aaagtcttcg
     6361 tattgtgaca ttcgctggtg aagcggtcac gcctgacctg cttgagatga gcgaaaagat
     6421 ttgtccttct gcagaattgg caaatgaata cgggcccaca gaaaatagtg tggcaacaac
     6481 aatattgcgt caactgaacg aaaaagagag gatcacgatc ggacacccga ttgcgaacac
     6541 aaaagtattt gttttacacg gaaatcaaat gcagccgatc ggcgcggcgg gtgaactgtg
     6601 tatttccggc acggggcttg ccagaggata ctacaaacag ccagagctga cagagaaagc
     6661 attctccgat catccgttcc ttgaagggga gcgtttatac cgaacaggtg atgcaggccg
     6721 ctttttgccg gatggaacga ttgaatatat aggacgtttt gatgatcaag tgaaaattag
     6781 gggttaccgc attgaactga aagaaattga aacggttctt cgacaggcgc caggagtgaa
     6841 ggaagcagca gtactggccc gtgatgtttc tgctgaggaa aaagagcttg ttgcttatat
     6901 cgttctggaa aagggaaaca atctcccgga tttgcatcgg cttcttgccg ggacattgcc
     6961 tccctatatg attccagcaa gtttcatcaa catcagccgg atgccattaa catccagcgg
     7021 gaagcttgac cgctcagcac ttcctgaacc agaaaacaat gcgagcctca catatatgcc
     7081 gccccgaact ttaatcgagg ctgatctcgc acatatttgg ggagatgtgc tgaataaaca
     7141 gcaaatcggc attcgtgatg atttctttca attaggcgga cagtccttaa aagcggccgc
     7201 actggtatca agaatacata aaaagcttaa tatcgagctg ccgatcagtg aggttttttc
     7261 taatccgaca gttgaaagca tggcagtcaa attgatgagc ttaaaagaac atgcttttac
     7321 acagattgat cctgcggatc aaagagatgt ctatccgctg tctttctcac aaaaacgatt
     7381 atatgctctc catcagctgg cagatgacag cacaggctat aacatgcccg ctgtacttga
     7441 attacgcgga aatctggatc gccagcggtt gagaagcgtt ctcacagaac ttgtgaatcg
     7501 gcatgaagca ttgcggactg tttttgtgct tgacagagga gagcccgtgc agatcattca
     7561 tccagagatg gcttttgatc tgaaagagct tgaaatggaa tcagaacaaa tgcttgagtc
     7621 cgcaatcgaa tcttttatca aaccgtttga tctattgtcc ggtccgcttt ttagagcatg
     7681 tgtcattaca atgggcaata atcgcggctt tttgctgctc gacatgcacc atattattgc
     7741 cgacggtgtc tcgatgcgca ctcttgtcca agaatttact gacttgtatt gcgaaaaaga
     7801 gttgccagct ttaaacctgc attataagga ttttgctgtt tggcagcaag aaaagtaccc
     7861 gaaagagcta tacaaaaaac aggaggccta ctggctcgat cagcttggcg ggagtcttcc
     7921 agtattagaa ttaccgcttg ataaaacaag accgcgtctc cctgatttca gcggcggaac
     7981 aatcgaagta aacattgata aagacacggc agatgagctg caccgtttaa tggttgaaac
     8041 gggaacaacg ttgtatatga ttcttctggc tgtctattct attttacttt ccaagctaag
     8101 cgggcaagag gatattgtcg tcggctcgcc tgctgccgga agactgcacg ccgatttgga
     8161 gcgcgtcatc gggatgttcg taaatacttt agcgatgcgc agccagcccg agggccacaa
     8221 aacgttcagc tcgtatttgc aggatattcg ccacctggct ctgacggctt acgagcatca
     8281 ggattatcct tttgaggagc tggcagataa gctcgataca catcgagagg taaatcgcaa
     8341 cccgctgttc gatgcgatgc tcgtgcttca aagcagtgag gatttccagt tcgaagtgcc
     8401 tggtctatca atttcgtctg tcactgcaaa acacgatata tctaaattcg atttgacatt
     8461 acacgctgag gagcattcgg gcgggattca ctgccggttt gaatacagca ccgctctttt
     8521 tgaagaagag accattgcgc gatgggcatc ccattttatt gaactggtga aaagtgtaac
     8581 ggctgatacc aagatgagaa tttcggaaat gcaattgctt cctgctgcag agcgcaattt
     8641 gctccttgaa aaaatgggac agtatgccgc ttatccgaga aatgaaaaca ttgtaagctt
     8701 atttgaaaag caagccgctg aacatccgga gcatctcgca gtggtgtatg gtcactctaa
     8761 gcttacttat cgagacctga atgaaaaagc tgagcggaca gctgctatgc tgatcaaaca
     8821 aggggtcaga actggcgata tcgtaggtct gatgctcgat cggtcacctg atatgatcat
     8881 tggcatttta tcgattttaa aagctggagg ggcctacttg ccgattgatc ctgaatatcc
     8941 tcaggaacgt atcagtttta tgctcaatga cagcggggca gaaatgttgc tgacagagcg
     9001 cggccaaaac aaacctgcag actacaacgg gcctattatg tatatcgatg aaggtgatag
     9061 cgactcaatt ccggatgatt taaacattca agaaacccta tcggatcagc cggcttacgt
     9121 gatatacaca tccggaacga ctggccagcc aaagggcgtc attgtcgagc accgcaatgt
     9181 gatcagtctt ttaaagcatc aaaacctgcc ttttaaattt ggccatgaag acgtctggac
     9241 gttctttcat tcatattgct ttgatttctc tgtatgggaa atgttcggtg cgttattaaa
     9301 cggaagtaca ctagtcgtgg tctctaaaga aacagcccgt gatccccatg cattccgatt
     9361 attgttaaaa aaagaacgcg tcactgtcct caatcagacc ccgacagctt tttacggcct
     9421 gatgcatgaa gatcaaaacc atacggatcg attaaacatc cgatacgtga tttttggcgg
     9481 cgaagcttta cagcccggca tgcttcaaag ctggaataaa aaatatcctc atactgatct
     9541 gatcaatatg tatggtatta cagaaacgac ggtacatgta acattcaaaa aattgtccgc
     9601 agcagacatt gcaaaaaata aaagcaatat cggacggccg ctttcaactc tgcaggctta
     9661 tgtgatggat gctcatatga atctgcagcc gatcggagtt ccaggggaga tgtatatagg
     9721 cggtgaaggt gtggcacggg gatatctcaa cagagatgag ctgaccgctg accgttttgt
     9781 gcctaatcct tatcttccgg gggatagatt ataccgaaca ggagatcttg ctaaacgcct
     9841 gtcaaatggc gagctggaat acttaggccg cattgatgat caggttaaag tcagagggca
     9901 ccgtattgag ttaggcgaaa tccaggcggc tcttcttcag cttccagcta ttaaagaggc
     9961 ggctgtcatc acaagaacag atgagaaagg gcaagcagct gtatatgcat acatcgtgac
    10021 aaaagatcaa caggccgcga atgcatcaga aatccggact tctctaaaaa ccatgctgcc
    10081 tgactttatg ctaccggccc gtttgataca gattgacagc atcccgctga ctgttaatgg
    10141 aaaacttgat cagaaagccc tgccggaacc tgataaacac ggttatattg ctgatgatat
    10201 cagaccaaga aatgagattg aaaaggtgat agctgaaatt tgggaggagc ttcttgatgt
    10261 ggaggagctg ggcgtaagcg ccaatttctt tgagcttggc ggagattcta ttaaagcact
    10321 gcaagtttgt gccagactga agcagcgcgg ctttgaaacg acagtacgtg agatgtttga
    10381 acatcagact cttggcgaac tgtccgcacg tgttcgaaaa gccgtacacg tcattgacca
    10441 aggtccggtc gaaggcgaga tcacttggac acctatccag caatggtttt tctcgcaatc
    10501 tctggaaatc aatcatttta accagtccgt tatgctctac cggactgaac gatttgacga
    10561 gacagcgctt aaaaaggtgc taaaaagcct ggtgactcat catgacgcac taagaatcgt
    10621 atgccggtat gaagatggca ggtcggtaca gataaacaga gggatagatc ttccagataa
    10681 ggagctatat gctcttgaac tgtttgatgt aaaggataac ttaacagaag cgcataacag
    10741 gattaaggaa gcagccagcc agatgcagga gcatttacgt ttggaaactg gtcccttgct
    10801 tcacgctgga ttgttcagga ccgagaatgg tgaccatttg tttctgacga ttcatcactt
    10861 agttgttgat gcggtttcgt ggcgcatttt gtttgaggat ttttcaacag cttacaaaca
    10921 ggaagtctca ggagaaacta ttaaactgcc gcaaaaaaca gattcatatt taacgtattc
    10981 acaaagaata gctgactact ctaaaagccg ccagatacag cgagaagaag cgtattggga
    11041 tgagcgagag aaccgtcaca ttcaacctat tcctaaagac aatgaagcag caccaaacac
    11101 attcaaagat acagaagtga ttgattttaa tctgtcccgc catcacacag aattattgtt
    11161 aacggctgca aataaagcat acagcacgga gatgaatgat attcttctga cagctttagg
    11221 ccttgctttg cagcaatgga cgggctatga ccagtttaaa atcagcatgg agggccatgg
    11281 aagggaatca tatcttgagg atattgacat tagcagaaca gtcggctggt tcacctcgat
    11341 ttatcctgta tggcttgata tgagcaattc tgatcataag aacaaagatg agcggctggg
    11401 ccacctcatt aaacagacaa aagatatgct gcaccgtata ccgcataagg gcgcaggcta
    11461 cggtgtgctg aaatatacca acaaaaaatg gggctctgag aaaggcagcc cggacatcag
    11521 ctttaattat ttaggccagt ttgatcagga tattcaatca aaagcctttg aggtttctga
    11581 catcaagcca gggaatgaga tcagcccgga atgggagcgg ccttatgcac tggatatcag
    11641 cggcgccgtt tcttcgggat gcctgaacat gcacatgatc tataacaggc ttcaatttga
    11701 gaaaaaaaca atccaaacat ttgcagagca ttttaaacag actctggaaa atatcattga
    11761 gcattgtacg ggcaaagaaa accgagaatg gagcgcatct gatttcactg atgaagattt
    11821 aacacttgat gaattgagtg agattatggg tgccgtcaac aaactatagg gagaggagat
    11881 tcacactgat gccgcagcaa cccgaaatac aggatatata ccctttgtct tttatgcagg
    11941 aagggatgct ttttcattca ctgtatgatg aacagtcaag agcttatttt gaacaggctt
    12001 cttttacgat ccatggacag cttgacttgg agcgtttcca gaaaagtatg gatgctgttt
    12061 ttgaaagata cgaaatcttc cgaacggcgt tcatctataa aaatgtagcc aaaccacgtc
    12121 aagtcgtgct caagcatcgt cattgccatg ttcattttga agatatttct catctcaacg
    12181 aaagagataa agaacattgt accgaggcat tcaaagagca ggataaatcc aggggattcg
    12241 atctccaaac agatgtactg atgagaatat ctattttaaa atgggcgcct aatcgttatg
    12301 tctgtatctg gagccatcat catattttaa tggatggctg gtgtttaggc atcgtcatta
    12361 aagattttct tcacatttat caagcgctgg gtaaaggtca gcttccgaat ttgcatcccg
    12421 ttcagccgta cgggacgtat attaaatggc tgatgcggca agaccgagaa gaagcagctg
    12481 agtattggaa aaagaggctt cagcatttcg aaaaagctac gcctctgccg aaaagaacag
    12541 atcaaatacc ggatgggaca ttagagcaga tcacgttcac catttctgaa aaagaaacct
    12601 ccgaattaca gaaaatcgca gcagcttctg gagcgacact aaacactgtt ttccaagctt
    12661 tatggggaat catgctccaa aagttcaatc gctgcggcga tgctgtgttc ggatccgtta
    12721 tatcaggcag accttctgag ctaagagatg tggaaaacat ggtcggactt tttatcaata
    12781 ccattcctat tcgagtccaa agtgattctc tttctttttc tgacctagtc agcaggatgc
    12841 aaaaagacat gactgaagca gaagcatata gttacttccc tttatatgac attcaggcgc
    12901 agagtgctct caaacaagag cttatcgatc atattatcgt ctttgaaaat acacctaccc
    12961 agcaagagat tgaagggctg aatcaggctg gatcatttga tttctccgtg aaggattttg
    13021 agatggaaga ggtgaccaat tatagctgca gtgtcaaagt gatcccaggc cgtacgttgt
    13081 acgttcggat tcatttttat accggcgctt atcaaccaaa catgatgtcc gagataaaag
    13141 attatttaca gcacatggtc tctgacgtca tctctgatcc atctcttccc gtgtcaaaga
    13201 tgacattgct agatgagaac aaaacacgga aaatcgtttc tcaaaacaac ggggcagtat
    13261 ctgtttcgcc tgaagcccca accctgcacg gtctgtttga acgacaggcg gctgtcacac
    13321 cggaacggcc ggccatccgc ttttccggcg gttcgctgac gtacgctgag cttgacatgt
    13381 atgccagccg gctggctgcg ggcctcgcgg cacgcggcgt cacgaaggaa agcatcgtcg
    13441 gtgtcctgtc tgaacggtca cctgaaatgc tgatagctgt acttgctgtc ttgaaggcag
    13501 gtggggcgta tttgccgctt gatcctgcat atccaaagga gcggctgagc tacatgctga
    13561 aagacagcgg ggccgcgctc ttgctggcac agccgggatg ttccgcaccg agcttttccg
    13621 gagagatgct tgaagtggac atggcatctc ttgcgagcga aaaagcagaa aacgatgtgt
    13681 ttactcctgc tgacggcggt tctctcgcct atgtcatcta tacatcgggc tccaccggga
    13741 agccaaaagg agtggccgtc gagcaccgcc aggctgtttc ctttctgact ggcatgcagc
    13801 gtcagtttcc gcttcaggaa gatgacattg ttatggtgaa aacctctttt tccttcgatg
    13861 cgtctgtgtg gcagctgttt tggtggtccc tttccggcgc ttcggcttat ctgcttccgc
    13921 ccggctggga gaaagacccg gcattgattg taaaagccat tcatcaggaa aaagtgacaa
    13981 cggctcattt tattccggct atgctgaaca gctttctcga tcaagcggaa atgaaagcgc
    14041 tcggtgatgg gacaagcctg aagcgtgtat tcgccggagg tgaaccgctt gcgccccatg
    14101 tggcagcccg ttttgcttct ttattgccgc aggtatcgct gatccatggc tacgggccga
    14161 cagaagcaac ggtagacgcg gcattttacg tgttggatcc agagcgggac agggatcgct
    14221 tgcggattcc gatcggaaaa cccgtacccg gtgcgcgttt gtatgtttta gatccgcatt
    14281 tagccgtaca gccttgcggg gtcgccggtg aactgtacat tgccggatcg ggtgttgcca
    14341 gaggttattt gaatcggcag gcattaacgg aggagcgttt tcttgaggac ccgttttacc
    14401 cgggtgaacg cgtgtacaaa accggggatt tggcgcgctg gctccctgac gggaatattg
    14461 aattcctcgg ccgcacggat gatcaggtga aaatccgcgg ctaccggatt gagcctggag
    14521 aaattgaagc a
//
