LOCUS       NZ_JALAVA010000005     22117 bp    DNA     linear   CON 26-JAN-2024
DEFINITION  Bacillus inaquosorum strain EC30O5B-F2-1 contig_0000005, whole
            genome shotgun sequence.
ACCESSION   NZ_JALAVA010000005
VERSION     NZ_JALAVA010000005.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus inaquosorum
  ORGANISM  Bacillus inaquosorum
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 1028849)
  AUTHORS   Dunlap,C.
  TITLE     Crop Bioprotection Bacillus Genome Sequencing
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1028849)
  AUTHORS   Dunlap,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-FEB-2022) CBP, USDA-ARS-NCAUR, 1815 N. University St.,
            Peoria, IL 61604, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC NGS Cell v. 21
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 429.34545439822875x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/24/2024 02:33:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,521
            CDSs (total)                      :: 4,448
            Genes (coding)                    :: 4,297
            CDSs (with protein)               :: 4,297
            Genes (RNA)                       :: 73
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 84 of 151
            Pseudo Genes (incomplete)         :: 86 of 151
            Pseudo Genes (internal stop)      :: 28 of 151
            Pseudo Genes (multiple problems)  :: 40 of 151
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:09:14
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 22117
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JALAVA010000005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     gene            complement(<1..2117)
                     /locus_tag="MOE81_RS12235"
                     /old_locus_tag="MOE81_12205"
     region          1..22117
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..22117
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22117
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<0:2117](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(<1..2117)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     CDS             complement(<1..2117)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Condensation_Starter (3-300). E-value:
                     2.1e-89. Score: 291.8. Matches aSDomain:
                     nrpspksdomains_MOE81_RS12235_Condensation_Starter.1"
                     /NRPS_PKS="Domain: AMP-binding (463-704). E-value: 1.7e-61.
                     Score: 200.0. Matches aSDomain:
                     nrpspksdomains_MOE81_RS12235_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389716.2"
                     /locus_tag="MOE81_RS12235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE81_12205"
                     /product="condensation domain-containing protein"
                     /protein_id="WP_268397494.1"
                     /sec_met_domain="Condensation (E-value: 2.9e-73, bitscore:
                     242.6, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 7.8e-56, bitscore:
                     185.4, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQHTYSLTHAQRRVWFTELLEPGTSICNLTACVKFRGNIDLDVL
                     EGALNHSISRNDAIRFQLLEGEELEPRLYLTEYKYTSLGIIDFSNVEMIEIEQWIQEQA
                     RIPFKLFNSPLYQFYLLRIHNHEVWLFAKFHHIIMDGISLNVMGNQIIDLYQKMKKQDP
                     LPDQPEPSYLSYIEKESQYLQSSRFTKDRLFWTQTFQNPPGYHSLAGQTSLQKQSTSAS
                     RDTITLSPHLGQTIRIFCEEQKINIISLFMASFYICISRITSKKDLAIGTYYGNRGSKA
                     EKEMLGMFVSSLPIRITVDPDADFLSFVRRVSREQLSVMRHQRFPYNLLVNELRKEQKD
                     LHNLIGISMQYQPLQWHNADGFDYETALYFSGYTANELSVQIQERTDTGNIQLNFDYQN
                     TLFSLEDIKRIQNHLLTLLENALQHPHSFIKELDMTNIREKQKLLYEFNKTEAVSPEAP
                     TLHGLFERQAAFTPERPAIRFSGGSLTYAELDMYAGRLAARLAARGVTKESIVGVLSER
                     SPEMLIAVLAVLKAGGAYLPLDPAYPEERLSYMLKDSGAALLLAQPGCSAPGFSGETLE
                     VDMASLASEEAESHVFAPADSGSLAYVIYTSGSTGQPKGVAVEHRQAVSFLTGMQRQFP
                     LQEDDIVMVKTSFSFDASVWQLFWWSLSGASAYLLPPGWEKDPALIVKAIHQEKVTTAH
                     FIPAMLNSFLD"
     aSDomain        complement(6..728)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE81_RS12235_AMP-binding.1"
                     /evalue="1.70E-61"
                     /label="MOE81_RS12235_AMP-binding.1"
                     /locus_tag="MOE81_RS12235"
                     /protein_end="704"
                     /protein_start="463"
                     /score="200.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FERQAAFTPERPAIRFSGGSLTYAELDMYAGRLAARLAARGVTKE
                     SIVGVLSERSPEMLIAVLAVLKAGGAYLPLDPAYPEERLSYMLKDSGAALLLAQPGCSA
                     PGFSGETLEVDMASLASEEAESHVFAPADSGSLAYVIYTSGSTGQPKGVAVEHRQAVSF
                     LTGMQRQFPLQEDDIVMVKTSFSFDASVWQLFWWSLSGASAYLLPPGWEKDPALIVKAI
                     HQEKVTTAHFIPAMLNSFL"
     aSModule        complement(6..2108)
                     /domains="nrpspksdomains_MOE81_RS12235_Condensation_Starter
                     .1"
                     /domains="nrpspksdomains_MOE81_RS12235_AMP-binding.1"
                     /incomplete
                     /locus_tags="MOE81_RS12235"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(258..317)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE81_RS12235_0007"
                     /evalue="2.80E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="MOE81_RS12235"
                     /protein_end="620"
                     /protein_start="600"
                     /score="35.1"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGQPKGVAVEH"
     CDS_motif       complement(501..542)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE81_RS12235_0006"
                     /evalue="4.10E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="MOE81_RS12235"
                     /protein_end="539"
                     /protein_start="525"
                     /score="19.8"
                     /tool="antismash"
                     /translation="LAVLKAGGAYLPLD"
     CDS_motif       complement(1065..1181)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE81_RS12235_0005"
                     /evalue="7.30E-10"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="MOE81_RS12235"
                     /protein_end="351"
                     /protein_start="312"
                     /score="31.4"
                     /tool="antismash"
                     /translation="SREQLSVMRHQRFPYNLLVNELRKEQKDLHNLIGISMQY"
     aSDomain        complement(1218..2108)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE81_RS12235_Condensation_Start
                     er.1"
                     /domain_subtypes="Condensation_Starter"
                     /evalue="2.10E-89"
                     /label="MOE81_RS12235_Condensation_Starter.1"
                     /locus_tag="MOE81_RS12235"
                     /protein_end="300"
                     /protein_start="3"
                     /score="291.8"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIIMDG"
                     /tool="antismash"
                     /translation="HTYSLTHAQRRVWFTELLEPGTSICNLTACVKFRGNIDLDVLEGA
                     LNHSISRNDAIRFQLLEGEELEPRLYLTEYKYTSLGIIDFSNVEMIEIEQWIQEQARIP
                     FKLFNSPLYQFYLLRIHNHEVWLFAKFHHIIMDGISLNVMGNQIIDLYQKMKKQDPLPD
                     QPEPSYLSYIEKESQYLQSSRFTKDRLFWTQTFQNPPGYHSLAGQTSLQKQSTSASRDT
                     ITLSPHLGQTIRIFCEEQKINIISLFMASFYICISRITSKKDLAIGTYYGNRGSKAEKE
                     MLGMFVSSLPIRITVD"
     CDS_motif       complement(1230..1319)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE81_RS12235_0004"
                     /evalue="8.80E-09"
                     /label="C5_starter_265-294"
                     /locus_tag="MOE81_RS12235"
                     /protein_end="296"
                     /protein_start="266"
                     /score="27.8"
                     /tool="antismash"
                     /translation="DLAIGTYYGNRGSKAEKEMLGMFVSSLPIR"
     CDS_motif       complement(1653..1718)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE81_RS12235_0003"
                     /evalue="7.00E-08"
                     /label="C3_starter_134-155"
                     /locus_tag="MOE81_RS12235"
                     /protein_end="155"
                     /protein_start="133"
                     /score="25.3"
                     /tool="antismash"
                     /translation="FHHIIMDGISLNVMGNQIIDLY"
     CDS_motif       complement(1923..2039)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE81_RS12235_0002"
                     /evalue="4.70E-10"
                     /label="C2_starter_024-063"
                     /locus_tag="MOE81_RS12235"
                     /protein_end="65"
                     /protein_start="26"
                     /score="32.1"
                     /tool="antismash"
                     /translation="ICNLTACVKFRGNIDLDVLEGALNHSISRNDAIRFQLLE"
     CDS_motif       complement(2064..2102)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE81_RS12235_0001"
                     /evalue="4.00E-03"
                     /label="C1_starter_004-017"
                     /locus_tag="MOE81_RS12235"
                     /protein_end="18"
                     /protein_start="5"
                     /score="10.1"
                     /tool="antismash"
                     /translation="YSLTHAQRRVWFT"
     misc_feature    2317..2330
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.77"
                     /tool="antismash"
     gene            complement(2488..3966)
                     /gene="dacB"
                     /locus_tag="MOE81_RS12240"
                     /old_locus_tag="MOE81_12210"
     CDS             complement(2488..3966)
                     /EC_number="3.4.16.4"
                     /GO_function="GO:0004175 - endopeptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0009002 - serine-type D-Ala-D-Ala
                     carboxypeptidase activity [Evidence IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="dacB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003241941.1"
                     /locus_tag="MOE81_RS12240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE81_12210"
                     /product="D-alanyl-D-alanine
                     carboxypeptidase/D-alanyl-D-alanine-endopeptidase"
                     /protein_id="WP_268397496.1"
                     /transl_table=11
                     /translation="MKKSIKLYVAVLLLFVVASVPYMHQAAQAAEKQGALAGQIDKILA
                     DHPALEGAMAGITVRSAETGAVLYEHSGEIRMRPASSLKLLTAASSLSVLGEDYSFTTE
                     VRTDGKFKGKKLNGNLYLIGKGDPTLLPSDFEEMAEKLKQSGVKEIKGNLMGDDTWYDD
                     IRLSPDMPWSDEYTYYGAQISALTASPNEDYDAGTVIVEITPGKKEGEKPAVSVSPKTD
                     YVTIKNDAETTAAGQKKDLTIEREHGTNTITIEGSVPVDASKTKEWIAVWEPAGYALDL
                     FKQALKKQGITVKGHVKTGAAPGSSDVLISHRSMPLSKLFVPFMKLSNNGHAEVLVKEM
                     GKVKKEEGSWEKGLEVLNNALPEFGVDPKSLVLRDGSGVSHINAVSSDQISQLLYDIQD
                     EKWFSAYLNSLPVAGNSDRMIGGTLRNRMKDTPAQGKVRAKTGSLSTVSSLSGYAETKS
                     GKTLVFSILLNGLIDDEDGKDIEDQIAVILANQS"
     gene            complement(4001..4978)
                     /gene="galM"
                     /locus_tag="MOE81_RS12245"
                     /old_locus_tag="MOE81_12215"
     CDS             complement(4001..4978)
                     /EC_number="5.1.3.3"
                     /codon_start=1
                     /gene="galM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389718.1"
                     /locus_tag="MOE81_RS12245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE81_12215"
                     /product="aldose 1-epimerase"
                     /protein_id="WP_268278745.1"
                     /transl_table=11
                     /translation="MANDIEKITYLGTPAIKAGNEHIEMIVVPEWGSNVISLVDKTTQL
                     QLLREPETAESFHDTPTLYGIPILFPPNRISDGTFSFRGRTYHFDINEKDKHNHLHGFL
                     YQEKWNVVTMKQTDEEVIVETEIDLSELPHVYKQFPHHAVVRMTYTLKGNTLFKHATVM
                     NKGKEAFPWGIGYHTTFVFPEESSLFSLTADQQWELDERLLPTGKLMDVPNKEALHEGM
                     DLRSQQLDDVFLSSYQKRGGENQAVIYHQHAHISIIYKADEQFKHWVVYNADGKQGYLC
                     PEPYTWVTNAVNLNVSPSLTGVQVLEPGEETTAKSSITIELNHQ"
     gene            complement(5111..6502)
                     /locus_tag="MOE81_RS12250"
                     /old_locus_tag="MOE81_12220"
     CDS             complement(5111..6502)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1086: MATE efflux
                     family protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389719.2"
                     /locus_tag="MOE81_RS12250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE81_12220"
                     /product="MATE family efflux transporter"
                     /protein_id="WP_268397497.1"
                     /transl_table=11
                     /translation="METSQEQLLTQKKSNPSVWRSMSLFLVPLLLSNVLQSVGQLVGMM
                     AVGRWLGVDAVAAVSSFFPLFFLLISFTIGIGSGSSILIGQAYGAKNEERLKAVVGTTL
                     TFTFLLGVVLAVIGSIFTLDILRLMGTPENVIHVSASYARILFYAMPFMFLYFAYTTFL
                     RGTGDSKTPFYTLIVSTVINIALLPVLILGMFGFPKLGIYGSAYATVISTIATFIVLMV
                     YLRKRNHPLQFDKTVRRYLKMDKELLALLLRLGIPSSINMILVSLSEIAVISFVNHYGS
                     NATAAYGVVNQVASYVQMPAVSLGIAVSIFAAQSIGANEFGRLKQVIRVGIWLNYIIGG
                     VLIILIYVFSHQILGLFLTEQETLYIAHRLLMITLWSYLLFGNAQIISATMRASGTVLW
                     PTVISIFAIWGVEVPVAFVLSHYTNLEILGVWVGYPAAFAVSLLLIYGYYQFVWKKKQI
                     TRLIQ"
     gene            6789..7334
                     /gene="iseA"
                     /locus_tag="MOE81_RS12255"
                     /old_locus_tag="MOE81_12225"
     CDS             6789..7334
                     /codon_start=1
                     /gene="iseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389720.2"
                     /locus_tag="MOE81_RS12255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE81_12225"
                     /product="DL-endopeptidase inhibitor IseA"
                     /protein_id="WP_268279473.1"
                     /transl_table=11
                     /translation="MKKCFLFLTTIALILSLSTNAFAKNTSGDLSQKQALQLALSAREH
                     FWNTMSGHNPKAKKAVCPSGTFEYQNLQYVYMCSDLGTKAKAVNYLTPIFTKTAIEKGF
                     KDYHFTVSKGKLAVPIGDGDNLLNWKKSTAKLISKKGGTVTYEFTVPTLDGSPAAKRKV
                     TFVKENNKWKVNQFDAVI"
     tRNA            complement(7424..7496)
                     /anticodon=(pos:complement(7461..7463),aa:Arg,seq:cct)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="MOE81_RS12260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="MOE81_12230"
                     /product="tRNA-Arg"
     gene            complement(7424..7496)
                     /locus_tag="MOE81_RS12260"
                     /old_locus_tag="MOE81_12230"
     gene            complement(7549..8094)
                     /locus_tag="MOE81_RS12265"
                     /old_locus_tag="MOE81_12235"
     CDS             complement(7549..8094)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389721.2"
                     /locus_tag="MOE81_RS12265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE81_12235"
                     /product="site-specific integrase"
                     /protein_id="WP_268272919.1"
                     /transl_table=11
                     /translation="MHIVQPIRSLEKIQDVKQYLLNKNERDYFLFIFGINSALRISDIL
                     PLQVKDVKNKDHLWATESKTKKKRKILILESLKHEIYEYTKDMKENEYLFKSVRTRKPI
                     SRIQAYRILREAAAACGLEEIGTHTLRKTFGYHFYQRTKDIAELQRILNHSSPSITMRY
                     IGIDEDTTRAAYKVFGGL"
     misc_feature    complement(8223..8237)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.7"
                     /tool="antismash"
     misc_feature    complement(8368..8382)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.34"
                     /tool="antismash"
     gene            complement(8410..8640)
                     /locus_tag="MOE81_RS12270"
                     /old_locus_tag="MOE81_12240"
     CDS             complement(8410..8640)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389722.1"
                     /locus_tag="MOE81_RS12270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE81_12240"
                     /product="excisionase family DNA-binding protein"
                     /protein_id="WP_003241933.1"
                     /transl_table=11
                     /translation="MYLTIKETAEYTNLSEDYIKSLVQGGKIRAVHDGEQFLIFKGQFK
                     THLEQLENYRALVQEILNEPIPEDIDVKDED"
     misc_feature    8734..8750
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 23.25"
                     /tool="antismash"
     misc_feature    8769..8785
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 22.85"
                     /tool="antismash"
     gene            8825..10588
                     /gene="ggt"
                     /locus_tag="MOE81_RS12275"
                     /old_locus_tag="MOE81_12245"
     CDS             8825..10588
                     /EC_number="2.3.2.2"
                     /GO_process="GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ggt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1274: gamma-glutamyltranspeptidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389723.1"
                     /locus_tag="MOE81_RS12275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE81_12245"
                     /product="gamma-glutamyltransferase"
                     /protein_id="WP_268272918.1"
                     /transl_table=11
                     /translation="MKRTWNVCLTALLSVLLVAGSVPFHAEAKKPPKSYDEYKQVDVGK
                     DGMVASAHPLASEIGADVLKKGGNAIDAAVAIQFALNVTEPMMSGIGGGGFMMVYDGKT
                     KDTTIIDSRERAPAGATPDMFLDEDGKAIPFSERVTKGTAVGVPGTLKGLEEALDKWGT
                     RSMKQLITPSIKLAEKGFPIDSVLADAISDYQEKLSRTAAKDVFLPNGEPLKEGDTLVQ
                     KDLAKTFKLIRSKGTDAFYEGKFAKALSDTVQDFGGSMTKKDLENYDITIDEPIWGDYQ
                     GYQIATTPPPSSGGIFLLQMLEILDDFNLSQYDVRSWEKYQLLAETMHLSYADRASYAG
                     DPEFVNVPLKGLLHPDYIKERQQLINLDQVNKKPKAGDPWKYQEGSANYKQVEQPKDKV
                     EGQTTHFTVADRWGNVVSYTTTIEQLFGTGIMVPDYGVILNNELTDFDAVPGGANEVQP
                     NKRPLSSMTPTILFKDDKPVLTVGSPGGATIISSVLQTILYHIEYGMELKAAVEEPRIY
                     TNSMSSYRYEDGVPEDVLSKLNGMGHKFGKSPVDIGNVQSISIDHENGTFKGVADSSRN
                     GAAIGINLKQK"
     gene            complement(10779..11636)
                     /locus_tag="MOE81_RS12280"
                     /old_locus_tag="MOE81_12250"
     CDS             complement(10779..11636)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389724.1"
                     /locus_tag="MOE81_RS12280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE81_12250"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_268274535.1"
                     /transl_table=11
                     /translation="MESGDLKIFRAVAREGSITKAARMLNYVQSNVTARIHNLEEDLKI
                     KLFHRTNRGMKLTAAGENLLQYAEQVLSLLDKAEKSAQMGQHPKGPLRIGSLETTAVTH
                     LPEHAASFLRRFPEVDLSVNTADTHNLIQQVLDHKVDGAFVYGPVEHTDIRQTPVSRDE
                     LVLISSREGTAEDMLRLPMLFFGAGCSHRARVKRLLKEAGIQNQKIIEFGTLEAILRGV
                     SAGLGTALLPKSAVDCSTHGANVYIHQLPAAYQDLEIVFIYRKDFFMTSAFQTFIDEVN
                     EMKR"
     gene            11765..12754
                     /locus_tag="MOE81_RS12285"
                     /old_locus_tag="MOE81_12255"
     CDS             11765..12754
                     /NRPS_PKS="Domain: PKS_ER (11-324). E-value: 6.8e-40.
                     Score: 129.0. Matches aSDomain:
                     nrpspksdomains_MOE81_RS12285_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389725.1"
                     /locus_tag="MOE81_RS12285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE81_12255"
                     /product="zinc-binding dehydrogenase"
                     /protein_id="WP_268274536.1"
                     /sec_met_domain="ADH_N (E-value: 1.6e-12, bitscore: 43.3,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 3.1e-28, bitscore:
                     94.5, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAVIHNGKTGLQGLSFQDVPSKKPGYGEVKVKLKSAGLNHRDLF
                     LMNNKSERDPHVILGSDGAGIIEEVGEGVKNVAVQTEVIIFPTLNWDLTENVPPVPEIL
                     GGPSDGTLAEYVIIPSQNAIKKPSYLSWEEAGVLPLSALTAYRALFTKAQLKKDEHLLI
                     PGIGSGVATYALFMAKAIGAKVSVTSRSEEKRKKALQLGADYAFDSYSNWDEQLQGEKA
                     DVVLDSIGPALFSEYFRHVKPNGRIVSFGASSGDDLSFPVRSLFFPQINVLGTSMGSCE
                     EFHDMLAFIEKHQLRPVLDRTYPLEKACGAYTRMQEGRQFGNIGIVME"
     aSDomain        11798..12736
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE81_RS12285_PKS_ER.1"
                     /evalue="6.80E-40"
                     /label="MOE81_RS12285_PKS_ER.1"
                     /locus_tag="MOE81_RS12285"
                     /protein_end="324"
                     /protein_start="11"
                     /score="129.0"
                     /tool="antismash"
                     /translation="LQGLSFQDVPSKKPGYGEVKVKLKSAGLNHRDLFLMNNKSERDPH
                     VILGSDGAGIIEEVGEGVKNVAVQTEVIIFPTLNWDLTENVPPVPEILGGPSDGTLAEY
                     VIIPSQNAIKKPSYLSWEEAGVLPLSALTAYRALFTKAQLKKDEHLLIPGIGSGVATYA
                     LFMAKAIGAKVSVTSRSEEKRKKALQLGADYAFDSYSNWDEQLQGEKADVVLDSIGPAL
                     FSEYFRHVKPNGRIVSFGASSGDDLSFPVRSLFFPQINVLGTSMGSCEEFHDMLAFIEK
                     HQLRPVLDRTYPLEKACGAYTRMQEGRQFGNI"
     gene            complement(12812..14293)
                     /gene="gltD"
                     /locus_tag="MOE81_RS12290"
                     /old_locus_tag="MOE81_12260"
     CDS             complement(12812..14293)
                     /EC_number="1.4.1.-"
                     /GO_component="GO:0009342 - glutamate synthase complex
                     (NADPH) [Evidence IEA]"
                     /GO_function="GO:0045181 - glutamate synthase activity,
                     NAD(P)H as acceptor [Evidence IEA]"
                     /GO_process="GO:0006537 - glutamate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="gltD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="other (smcogs) SMCOG1285: ferredoxin fdxC"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389726.2"
                     /locus_tag="MOE81_RS12290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE81_12260"
                     /product="glutamate synthase small subunit"
                     /protein_id="WP_133489195.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.5e-27, bitscore:
                     92.7, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKPTGFMEIKREKPAERDPLTRLKDWKEYSAPFSEEASKRQGAR
                     CMDCGTPFCQIGADINGFTSGCPIYNLIPEWNDLVYRGRWKEALERLLKTNNFPEFTGR
                     VCPAPCEGSCTLAISDPAVSIKNIERTIIDKGFENGWIQPRIPKKRTGKKVAIVGSGPA
                     GLASADQLNQAGHSVTVFERSDRAGGLLTYGIPNMKLEKGIVERRVKLLTQEGIDFVTN
                     TEIGVDITADELKEQFDAVILCTGAQKQRDLLIEGRNSKGVHYAMDYLTLATKSYLDSN
                     FKDKKFIDAKGKDVIVIGGGDTGADCVATALRQKAKSVHQFGKHPKLPPARTNDNQWPE
                     QPHVFTLEYAYEEAEAKFGRDPREYSIQTKKMVADKNGKLKELHTIQMEKVKNEHGKYE
                     FRELPGTEKVWPAQLVFIAIGFEGTEQPLLKQFGVNSVNNKISAAYGDYQTNIDGVFAA
                     GDARRGQSLIVWAINEGREVAREVDRYLMGSSVLP"
     misc_feature    complement(14262..14275)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 20.8"
                     /tool="antismash"
     gene            complement(14310..18872)
                     /gene="gltB"
                     /locus_tag="MOE81_RS12295"
                     /old_locus_tag="MOE81_12265"
     CDS             complement(14310..18872)
                     /EC_number="1.4.1.13"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0015930 - glutamate synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006537 - glutamate biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0006807 - nitrogen compound metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="gltB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389727.2"
                     /locus_tag="MOE81_RS12295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE81_12265"
                     /product="glutamate synthase large subunit"
                     /protein_id="WP_268274537.1"
                     /transl_table=11
                     /translation="MTYNQMPKAQGLYRPEFEHDACGIGLYAHLKGKQTHDIVKQGLKM
                     LCQLDHRGGQGSDPDTGDGAGLLVQIPDAFFRKECKDINLPEKGRYGVGMVFFSQKEDE
                     RIKIEKQINALIEQEGQAVLGWRTVPVNVGKIGTVAQKSCPFVRQVFIGASSDLKDNLS
                     FERKLYVIRKLAENWGVTEGLDFYFASLSSQTIVYKGLLTPEQVDAFYSDLQDEAFVSA
                     FALVHSRFSTNTFPTWERAHPNRYLVHNGEINTLRGNINWMRAREQQFVSESFGEDLNK
                     ILPILNADGSDSSILDNAFEFFVMAGRKPAHTAMMLIPEPWTENTHMSKEKRAFYEYHS
                     SLMEPWDGPTAISFTDGKQIGAILDRNGLRPARYYVTKDDYIIFSSEVGVIEVEQENVL
                     YKNRLEPGKMLLIDLEEGRIISDEEVKTQIATEFPYQKWLEEELVQVNPDPESREEEQF
                     TDLLTRQKAFGYTYEDIQKYLIPVIKEGKDPLGSMGNDAPLAVLSDRAQSLFNYFKQLF
                     AQVTNPPIDAIREQLVTSTMTWLGAEGDLLHPSERNVRRIKLYTPVLSNEQFYALKTIV
                     HPDLKSQKIDVLFSEDLERGLKDMFTQAEKAISQGVSLLILSDKKMNGRLTPIPPLLAV
                     SALHQHLIRKGLRTKVSIIVESGEAREVHHFAALIGYGADAINPYLAYATYKQEIDEGR
                     LDISYEEAVSKYGKSITEGVVKVMSKMGISTVQSYRGAQIFEAVGISRDVIDRYFTGTA
                     SQLGGIDLNTIAEEAQRRHREAYQDDYSKTLEPGSDFQWRNGGEHHAFNPKTIHTLQWA
                     CRRNDYNLFKQYTKAADEERIGFLRNLFAFDGDRKPLKLEEVESAESIVKRFKTGAMSF
                     GSLSKEAHEALAIAMNRLGGKSNSGEGGEDPKRFVPDKNGDDRRSAIKQIASGRFGVKS
                     HYLVNADELQIKMAQGAKPGEGGQLPGNKVYPWVADVRGSTPGVGLISPPPHHDIYSIE
                     DLAQLIHDLKNANRDARISVKLVSKAGVGTIAAGVAKATADVIVISGYDGGTGASPKTS
                     IKHTGLPWELGLAEAHQTLMLNGLRDRVVLETDGKLMTGRDVVMAALLGAEEFGFATAP
                     LVVLGCVMMRACHLDTCPVGVATQNPELRKKFMGDPDHIVNYMLFIAEEVREYMAALGF
                     KTFDEMIGRTDVLHVSERAKAHWKASQLDLSTLLYQPEGVRTFQSPQNHKIDQSLDITA
                     ILPAVQEAIESGKEADVSIQINNTNRVAGTITGSEISKRYGEEGLPEDTIKLQFTGSAG
                     QSFGAFVPKGMTLYLDGDSNDYVGKGLSGGKIIVKSPEGFNSASDDNVIIGNVAFYGAT
                     SGEAYINGRAGERFAVRNSGVNVVVEGIGDHGCEYMTGGSVVVLGDVGKNFAAGMSGGI
                     AYVLAEDVKAFKRKCNLEMILFESLEDEKETQKIKAMLEKHAAYTNSQKATDLLDQWED
                     SVKKFIKVIPKNYKQMLASIEEQKAAGLSDEEAVMYAFEANTKPKQNTASSGQKQAVVQ
                     "
     misc_feature    complement(18985..18999)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: medium, score: 22.93"
                     /tool="antismash"
     gene            19019..19921
                     /gene="gltC"
                     /locus_tag="MOE81_RS12300"
                     /old_locus_tag="MOE81_12270"
     CDS             19019..19921
                     /codon_start=1
                     /gene="gltC"
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389728.2"
                     /locus_tag="MOE81_RS12300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE81_12270"
                     /product="glutamate biosynthesis transcriptional regulator
                     GltC"
                     /protein_id="WP_019258572.1"
                     /transl_table=11
                     /translation="MELRQLRYFMEVAEREHVSEAADHLHVAQSAISRQIANLEEELNV
                     TLFEREGRNIKLTPIGKEFLIHVKTAMKAIDYAKEQIDEYLDPHRGTVKIGFPTSLASQ
                     LLPTVISAFKEEYPHVEFLLRQGSYKFLIEAVRTRDIDLALLGPVPTNFPDITGKILFT
                     EKIYALVPLNHPLAKQKTVHLIDLRNDQFVLFPEGFVLRKMAIDACKQAGFAPLVSTEG
                     EDLDAIKGLVSAGMGVTLLPESTFAETTPRFTVKIPIEFPQVKRTVGIIKPKNRELAPS
                     ANDFYEFVIQFFSKLEQYQ"
     gene            complement(19976..21091)
                     /gene="proB"
                     /locus_tag="MOE81_RS12305"
                     /old_locus_tag="MOE81_12275"
     CDS             complement(19976..21091)
                     /EC_number="2.7.2.11"
                     /GO_function="GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="proB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003241920.1"
                     /locus_tag="MOE81_RS12305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE81_12275"
                     /product="glutamate 5-kinase"
                     /protein_id="WP_003241920.1"
                     /transl_table=11
                     /translation="MTSDTNMKRVVVKIGSSSLTSLHGEISIRKLEALVDQIAKLKDAG
                     YEVILVSSGAVAAGYRKLGFIQRPEKLPEKQASASIGQGLLMEAYSKLFLAHGYVASQI
                     LITRNDFSDEYRYNNVRNTMNVLLERGIIPIINENDTVTVNRLKFGDNDTLAAKVAGLI
                     DADMLVILSDIDGLYDGNPRTNPEAKRMQRVSEITPDIEACAGDTGSGVGTGGMRSKLD
                     AFKIVMASGIKGFLGQADAKDILYKAVHQEAEGTYFEAEGTLPLNHKEQWIAFNSGPEG
                     EMILSDDYSRKITNGQSSLYLDGVQEIKGKFKSGSVVRLMDSQGAEIGLGIVNYSSVQL
                     QELDKKKELMNKAVIDQEAFVCHVDLSLPVY"
     gene            complement(21088..21981)
                     /gene="proC"
                     /locus_tag="MOE81_RS12310"
                     /old_locus_tag="MOE81_12280"
     CDS             complement(21088..21981)
                     /EC_number="1.5.1.2"
                     /GO_function="GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA]"
                     /GO_process="GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="proC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389730.2"
                     /locus_tag="MOE81_RS12310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE81_12280"
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="WP_080030916.1"
                     /transl_table=11
                     /translation="MRTKKRTKEMLPIFDQKKVAFIGAGSMAEGMISGIVRANKIPKQN
                     ICVTNRSNTERLAELELQYGITGATPNELCIEDMDVLILAMKPKDAESALSSLKSRIQP
                     HQLILSVLAGITTSYIEQSLLNEQPVVRVMPNTSSMIGASATAIALGKYVSKDLKKLAE
                     ALLGCMGEVYTIQENQMDIFTGIAGSGPAYFYYLMEFIEKTGEEAGLDKQLSRSIGAQT
                     LLGAAKMLMETGEQPEVLRDNITSPNGTTAAGLQALKKSGGGEAISQAIKHAAMRSKEI
                     SDDIEKTAAPLSGVIK"
ORIGIN
        1 ttatcgagaa agctgttcag catagccgga ataaaatgag ccgttgtcac tttttcctga
       61 tgaatggctt ttacaatcaa tgccgggtct ttctcccagc cgggcggaag cagataagcc
      121 gaagcgccgg aaagggacca ccaaaacagc tgccacacag acgcatcaaa ggaaaaagag
      181 gttttcacca tgacaatgtc atcttcctga agcggaaact gacgctgcat gccagtcaga
      241 aaggaaacag cctggcggtg ctcaaccgct accccttttg gctgcccggt ggagcccgac
      301 gtatagatga cataggcgag agagccgctg tcagcaggag caaatacatg gctttctgct
      361 tcttcgctcg caagggatgc catgtccact tcaagcgtct ccccggaaaa gcccggtgcg
      421 gaacatcccg gctgtgccag caagagcgcg gccccgctgt ctttcagcat gtagctcagc
      481 cgctcctctg gatatgcagg atcaagcggc aaatacgccc cgcctgcctt caagacagca
      541 agtacagcta tcagcatttc aggtgaccgt tcagacagga caccgacgat gctttccttc
      601 gtgacgcctc gtgccgcgag gcgcgcggcc agacggccgg catacatgtc aagctcagcg
      661 tacgtcagcg aaccgccgga aaatcggatg gccggccgct ccggtgtgaa agccgcctgt
      721 cgttcaaaca gtccgtgcag ggtcggggct tcaggcgaaa cagcttccgt cttattaaac
      781 tcatacaaca atttttgttt ctctcttata ttagtcatat ctaattcttt tatgaaactg
      841 tgcggatgtt gaagggcgtt ttccagtaac gtaagcagat ggttctgtat tcgcttaata
      901 tcctcaagag aaaacaaggt attttgatag tcgaaattta attgaatatt tccggtgtct
      961 gtccgttcct gtatttgaac agaaagctcg ttcgcggtgt atccgctgaa ataaagcgcc
     1021 gtttcatagt caaaaccgtc tgcattgtgc cattggagcg gttgatactg catagatata
     1081 ccgataaggt tgtgtaaatc cttctgttct tttcttaatt catttacaag caaattataa
     1141 ggaaaccgtt ggtgacgcat aacggaaagc tgttccctgc ttactctgcg gacaaaggat
     1201 agaaagtccg cgtcaggatc aaccgttatt ctgatgggaa gagaactgac gaacatgccg
     1261 agcatttctt tttcagcctt tgaccctctg ttgccatagt aggtgccgat ggcaaggtct
     1321 tttttagaag tgatccggct gatgcatatg taaaatgaag ccataaataa ggaaatgata
     1381 ttgatctttt gttcttcgca aaagattcga atcgtttgcc ctagatgagg tgaaagggtg
     1441 atggtatctc tggatgcgga tgtgctctgt ttttgtaaag acgtctggcc ggctaacgag
     1501 tggtatcccg gcggattctg aaaggtttga gtccaaaata aacggtcctt tgtaaaacgt
     1561 gaagactgta aatattgact ctctttttcg atgtagctca agtaagaagg ttcaggctga
     1621 tcgggtaaag gatcttgctt tttcattttt tgataaagat ctataatttg atttcccatc
     1681 acgtttaagg agatgccgtc cattataata tgatggaatt tagcaaacag ccaaacctca
     1741 tgattgtgga ttctaaggag ataaaattga taaagaggcg agttgaatag tttaaatggg
     1801 attctcgctt gttcttgtat ccattgctct atttctatca tttcaacatt tgaaaaatct
     1861 attattccca atgaagtata tttatattca gtaaggtaca atcgcggctc aagctcttct
     1921 ccttctagca gctgaaacct gatggcatcg ttgcgggaga tggaatgatt cagcgcgccc
     1981 tctagaacat caagatcaat attgcctctg aatttcacac aggccgtaag attgcaaatg
     2041 ctggtacctg gctccagcag ttcggtaaac cacactctcc tttgggcatg ggttaaagaa
     2101 taagtatgtt ggctcaacgg attccctcca gttctcataa taagagagta agaaaaaagt
     2161 agaaaaatga caataaaaga aattatatga ctatataatc catatatgca ctatattaac
     2221 ggatattttt taaagtacaa taaaaaatat taaattttta taacattttt ttgaatatag
     2281 tattatttct ttagttttgg tttctttctt catcaaattt tttaatataa agtgataaaa
     2341 gtatcattct gattcgggtc ttacacacta atttttcaat tgtgctaatt tgctgttgcg
     2401 cgtaatcttt ctatttgttg gcagatgcga ccggaatatt attgaagaca taaaaaaacc
     2461 tgttttcctt ggaaaacagg tctgacgcta tgattgattt gccaagatga cagcgatttg
     2521 atcctcgata tcttttccat cctcgtcatc aatcaatccg ttcaaaagaa tagaaaaaac
     2581 aagggttttt ccgctcttgg tttctgcgta cccggataaa gagctgactg tgcttaacga
     2641 tccggttttt gcccttacct ttccttgtgc aggagtgtct ttcatccggt tcctcagtgt
     2701 tccgcctatc atcctgtcac tattgcccgc aaccggcaga gaatttagat aagctgagaa
     2761 ccatttctca tcttgaatgt catataacag ctgtgagatt tgatctgagg atacagcatt
     2821 aatatgggag acacctgatc cgtctcttaa gacaagtgat ttgggatcaa caccaaattc
     2881 cggaagcgca ttgtttaata cttcaagtcc cttttcccag cttccttctt cttttttcac
     2941 tttccccatc tcttttacga gcacttcggc atgtccgtta ttgcttaatt tcataaacgg
     3001 cacaaatagt tttgacagag gcattgagcg atgagagatt aacacgtctg aagaaccggg
     3061 cgcagcgcct gtcttgacgt gcccctttac agtaattcct tgttttttta gtgcctgctt
     3121 aaataaatcc aaagcgtatc cagccggctc ccagacagca atccattcct ttgtcttgct
     3181 tgcgtcaacc ggtacgctcc cttcaattgt gatcgtgttt gttccatgct ctctttcgat
     3241 cgtgaggtct ttcttttggc cagccgcagt cgtttcggca tcgttcttaa tcgttacata
     3301 atccgtcttc ggagatacag aaacggcagg cttttccccc tcttttttac ccggggtgat
     3361 ctctacaatc acagtgcctg catcataatc ttcattcgga gacgctgtta aagcggagat
     3421 ttgcgcgccg taatatgtgt attcatcact ccacggcata tcaggcgata atctgatgtc
     3481 atcataccac gtatcatcac ccatcagatt gcctttgatc tctttcacgc cggattgttt
     3541 caatttctca gccatttctt caaaatcaga tggtaaaagt gtcggatctc ctttccctat
     3601 caaataaagg tttccattca gctttttccc tttaaatttg ccgtccgtcc ggacctcggt
     3661 tgtaaaggaa tagtcctcgc caagaacaga aagtgatgag gccgctgtca aaagttttaa
     3721 agaagaggcg ggcctcattc ggatctctcc tgaatgctca tatagaacag cgcctgtttc
     3781 cgcagaacga acggtgatgc cggccattgc gccttcgagt gcaggatgat cagctaaaat
     3841 cttatcgatc tgcccggcaa gtgcaccttg tttttcagcc gcttgcgcag cctgatgcat
     3901 ataaggtacc gaagcaacga cgaaaagcag caaaacagca acataaagct ttatgctttt
     3961 tttcattttt ttaccccgcc tctctgcgcc tcatcatggg ctattgatga ttcagttcaa
     4021 tggtgatact gcttttggct gtcgtttctt ctcccggctc cagcacttgt acaccagtga
     4081 gtgatggaga cacattaaga ttcacagcgt ttgtcaccca tgtgtaaggt tcagggcata
     4141 aatatccctg ctttccgtcc gcgttgtata caacccaatg tttaaattgt tcatctgcct
     4201 tataaataat gcttatatgt gcatgctgat gataaatgac tgcctgattt tctccgcccc
     4261 ttttctgata agaagataaa aagacatcat ccagctgctg gctgcgtaaa tccatccctt
     4321 catgcaaggc ttctttattc ggtacatcca tcagtttccc ggtcggcagc aggcgctcat
     4381 ccaactccca ttgctgatct gctgtcaggg agaataacga gctttcttct ggaaatacaa
     4441 atgtagtatg atagccgatt ccccaaggaa acgcttcctt tcctttgttc atgaccgtcg
     4501 catgtttaaa tagagtattc ccctttagcg tgtatgtcat ccgaacgacg gcatgatgcg
     4561 gaaattgctt atacacatgg ggaagctctg aaaggtcaat ttcagtttca acgatcactt
     4621 cttcatcagt ttgcttcatg gtcactacgt tccatttttc ctgataaaga aacccatgaa
     4681 gatggttgtg tttatccttt tcattgatat caaaatgata tgttctgccc cggaaactga
     4741 atgtaccgtc acttatccgg ttaggcggaa acaggatcgg aatgccatac aatgttggtg
     4801 tatcatgaaa gctttctgct gtttccggtt cacgcaaaag ctgaagctgt gtcgttttgt
     4861 ccacaagaga aatgacgttg ctcccccact cgggaacgac aatcatttct atatgttcgt
     4921 tgcctgcttt gatggcaggt gttcctaaat acgtaatctt ctcaatatcg tttgccatgt
     4981 gtactcaacc tctccttgat tcattgcttg tataagaatt caatgtaatg tgccatattt
     5041 cctccattta tgttttctct ttatcaaaca aaaaacaccg ttcaaatgtt gaacggtgtg
     5101 attcgggatg ctattggatg agacgtgtaa tctgtttctt tttccaaacg aattgataat
     5161 acccataaat caacagcaag ctgacggcaa acgcagccgg atagccaacc cagacgccga
     5221 gtatttcaag atttgtgtag tgggaaagta cgaacgcgac aggcacctct actccccaga
     5281 tggcaaaaat actgataacg gtcggccata aaaccgttcc gcttgcccgc atcgtcgcag
     5341 aaataatttg ggcatttcca aagagtaagt aactccacaa tgtaatcatc aagagacggt
     5401 gcgcaatgta aagcgtctct tgttcggtta aaaataatcc taaaatctga tgtgaaaaaa
     5461 catagatcag aatgatcagc acaccgccaa tgatataatt cagccaaatc ccgacacgaa
     5521 ttacctgttt taggcggcca aactcgttcg ctccgatcga ttgcgcggcg aatatagaca
     5581 ccgcaatacc aaggctgacg gccggcatct gcacatagct ggctacctgg ttgaccacgc
     5641 cgtatgcagc tgtcgcatta gagccgtaat ggttgacgaa tgaaataacc gctatctctg
     5701 ataatgagac gagaatcata ttgatgcttg atggaatccc gaggcgcagc aggagtgcca
     5761 gcagttcttt atccattttc aaataacggc gcactgtttt atcaaattgc agcggatggt
     5821 ttcgttttcg caaatacacc attaacacaa taaaagtcgc aatcgtggaa atgacggttg
     5881 catatgcgga gccgtatatg cccagtttcg gaaaaccgaa catgccaagg atcaagacag
     5941 gcaaaagcgc tatgttaatg accgtgctca caatcagcgt ataaaaaggt gtcttagaat
     6001 ccccagttcc gcgcaaaaat gttgtataag caaaatataa aaacataaac ggcatcgcgt
     6061 aaaataaaat acgtgcatag ctggcgctga catgaattac attttcaggc gtgcccatta
     6121 aacgaagaat atccaaggtg aaaatactgc cgatgacggc taacacaacc cctaataaaa
     6181 acgtaaacgt gagcgtcgtc ccgacaacag cctttaaccg ctcctcattt ttcgccccgt
     6241 aggcttgtcc gatcaggatc gaacttcctg aaccgatccc gattgtaaat gagattaaaa
     6301 gaaaaaataa cgggaaaaag gatgatacag ctgcaaccgc atcaacacca agccatctgc
     6361 ctacagccat catcccgact agctggccga ctgattgcag cacattgctt agcagcagcg
     6421 gaactaaaaa gagtgacata gaccgccaga cagatggatt gcttttcttc tgagttaaaa
     6481 gttgttcttg tgatgtttcc atattgaaag ctcctttatt tgcattcgtt tgtaaacatg
     6541 atcctattct tttgacaaaa acaggatatg taacatgata ttattcatca ctgtacatat
     6601 gaaacccttc ccgattcttc taattttaca catcttttta gcttatgaag aataaactag
     6661 caagtaacag cctatttcct tgtgagtaaa agaataaaaa ataatttatg caaaagtatt
     6721 gtaatctatc cgtaattatt gtaacatttg taacataaga gaaagagatt ttgaaggagt
     6781 gaactacaat gaaaaaatgt tttctatttc taacaactat tgcacttatt ctgtcattaa
     6841 gcacaaatgc atttgcgaaa aatacttcag gtgatttatc acaaaaacaa gcactgcagc
     6901 tggcgttatc agcaagagag catttttgga acacaatgag cggccacaat ccaaaagcga
     6961 aaaaagcagt ttgcccatca ggcacatttg agtatcaaaa tcttcaatac gtgtacatgt
     7021 gcagtgacct aggcactaaa gcaaaagcag tgaattactt aactcctatt ttcacaaaaa
     7081 cagcaattga aaaaggcttt aaagactatc atttcactgt ttcaaaagga aaacttgcag
     7141 ttccaatcgg cgacggagat aaccttttga attggaaaaa atcaactgct aaactgatct
     7201 ctaaaaaagg cggcacagtc acatacgaat ttaccgttcc tactttagac ggatcacctg
     7261 cagcgaaacg gaaagtgaca tttgtaaaag aaaataataa atggaaagtc aatcaatttg
     7321 acgcagttat ataataaaaa acgccctgca taagcgggcg tttttttatt tggcataaag
     7381 aaagacaaca gacgaaaagc ccgttgtctt tttgtaagta taacgctcta ggagagattc
     7441 gaactcccga cctgcagttt aggaaactgc tgcactatcc gctgtgctac tagagctttt
     7501 ggtatttata tagtagctct gatgatgaat attttcaagt ggtttgtatt aaagccctcc
     7561 aaaaacctta tacgcggccc ttgtcgtatc ttcatcaata ccgatatacc gcattgtaat
     7621 cgagggtgat gaatgattca gtattctctg cagctcggca atgtcttttg tccgctgata
     7681 aaaatgatag ccgaacgttt tccgcagcgt atgcgtccct atctcctcga gtccgcacgc
     7741 cgcggcggcc tctcttaaaa tcctgtaggc ctgaatacgg gaaatcggct tcctggtccg
     7801 gacagattta aaaagatatt cgttttcctt catgtctttc gtatactcgt atatttcgtg
     7861 tttcagcgat tctaaaatca gaatcttcct tttctttttc gttttgcttt cagtcgccca
     7921 taaatgatct ttatttttaa catccttcac ttgaagcggc agaatatcag aaatgcggag
     7981 cgcgctgttg atgccgaaaa taaacagaaa ataatcccgc tcgtttttgt ttagcaaata
     8041 ctgttttaca tcttgaattt tctctaagct gcgaatcggc tgtacaatat gcatccaaaa
     8101 actccttaaa aaccgttatg taacgttttg aggtctatgt tactattata gctgaaaaac
     8161 gttgaaagtc aaagtacggc ggcgtttatg taacataata tacatagtgt tacataggct
     8221 ggtgaaaaag cttttcagaa cctcctccct cttaaatgag ttttaaagcc tcttataaag
     8281 cttttaatct atttgataca tattccccta tctatcatca aaaagcctct tagaacaaaa
     8341 tctgacgctt cggttttttc gctgttttga aaaagatata caaaaaaaga cacaatttga
     8401 aattgtgtcc tagtcctcat cctttacatc gatatcttcc gggattggtt catttaagat
     8461 ttcctgcacg agtgctctgt aattctctag ctgttcgaga tgcgttttga actgcccctt
     8521 aaaaattaaa aattgctcac cgtcatgaac ggctctgatt tttcctccct gcaccaaact
     8581 tttaatataa tcctctgaaa gatttgtata ttctgctgtt tctttaatcg ttaaatacat
     8641 atagcagtcc tttcttaatc cgtatgctga ttctaatata gcacatggct cataacaata
     8701 taatcaattt cacacagaaa agcgggtgaa tgttctatat aatataccat ttgtcacttg
     8761 tgaaaacgct gtaatttttt tacgctaaga ttgtaacata acagcttcat ataggaggga
     8821 gaacatgaaa agaacgtgga acgtctgttt aacagctctg cttagtgttc tgttagtcgc
     8881 tggaagtgtc ccttttcacg cggaagcgaa aaagccgccc aaaagctatg acgagtacaa
     8941 acaagtagat gttgggaaag acggcatggt tgctagcgca catcctctcg cttcggaaat
     9001 cggtgctgat gtactgaaaa aaggaggaaa tgccattgac gcggcagttg ccattcaatt
     9061 tgcgctcaat gtaacagagc cgatgatgtc aggcattggc ggcggcggtt ttatgatggt
     9121 gtatgatgga aaaacaaagg atacaacgat cattgacagt cgtgaacgcg ctccagcagg
     9181 tgcaactcct gatatgtttc tcgatgaaga cggcaaagcg attcctttct ctgaacgtgt
     9241 gacaaaaggt actgccgtcg gtgttccagg tacgctgaaa gggctggaag aagctctgga
     9301 taaatgggga acccgttcaa tgaagcaatt aatcacccct tctattaaac tcgctgaaaa
     9361 aggctttccg attgattcgg tgttggcaga tgcgatttct gattatcagg aaaagctgtc
     9421 acggactgcc gcaaaagatg tatttttgcc aaatggagag ccgcttaaag aaggcgatac
     9481 actggttcaa aaggatttgg caaaaacgtt taagctcatt cgctcaaaag gcactgacgc
     9541 tttttatgaa ggaaaattcg ccaaagcgct ttctgacact gtacaggatt tcggcggatc
     9601 aatgacgaaa aaggatttag aaaattatga catcacaatc gatgaaccga tttggggaga
     9661 ctatcaaggc tatcaaatcg ccactactcc tcctccaagc tctggcggta ttttcttatt
     9721 gcaaatgctg gaaatacttg atgattttaa cctttcacaa tacgatgtcc gctcatggga
     9781 aaaatatcaa ctgcttgctg aaacgatgca tttgtcttat gccgaccgtg cgtcttatgc
     9841 aggtgatccc gaatttgtaa acgttcctct caaaggcctg cttcaccccg attatattaa
     9901 agaacgccag caattaatca acttagatca agtcaataaa aaaccgaaag ccggtgatcc
     9961 ttggaaatac caagaaggat cagcaaacta taagcaagtc gaacagccga aagacaaagt
    10021 agaaggccaa acaacccact ttacagttgc cgaccgctgg ggaaatgttg tttcctacac
    10081 gacgacaatt gaacagctat tcggaacggg tattatggtc cctgattacg gcgtcatttt
    10141 aaacaatgaa ctaacagatt ttgatgcggt tccaggcgga gccaacgaag tacagccaaa
    10201 caaacggcct ttaagcagta tgaccccgac cattttattt aaggatgata agcctgtcct
    10261 caccgtcgga tctcctggcg gggccaccat tatttcgtcc gttttgcaaa ccattctcta
    10321 tcacatcgaa tatggcatgg aattaaaagc agctgttgaa gagccgagaa tttacacaaa
    10381 cagcatgagc tcttaccgct atgaagacgg agttcctgaa gatgttctca gcaaactaaa
    10441 cggcatgggc cacaaattcg gaaaaagccc ggtggatatc ggaaacgtac aaagcatttc
    10501 tatcgaccat gaaaacggca cctttaaagg cgtagctgat tcaagtagaa acggcgcggc
    10561 gatcggcatt aatttaaaac agaaataaaa ggaaaaaact gtactcgctt caattgagta
    10621 cagttttttt gtatgcagac ctttatataa gaacggaaac aacatcctcc tgcctatatc
    10681 aatccgaatg cctttaatac ggtttggtga tactccatat gccggctttc ttgacaatcg
    10741 gctacgttct tagttcagct tatgcagcgt aacagtcttc atcttttcat ttcgtttacc
    10801 tcatcaataa atgtctggaa cgcactcgtc ataaaaaagt cttttctgta tataaatacg
    10861 atctctaagt cttgatacgc tgctggcagc tgatgaatat atacatttgc accatgggta
    10921 gagcagtcaa cagcggactt cgggagcagc gccgtgccca aaccggcgga tactcctctt
    10981 aaaatagctt ccaatgtgcc aaactctatg attttttgat tttgaatacc tgcttccttc
    11041 agcaacctct tgaccctggc acgatgagaa cagccagccc caaaaaagag catcggcagc
    11101 cgaagcatgt cttctgccgt cccctcccgt gatgaaatca aaaccaattc atcacgggaa
    11161 acaggggttt gtctgatatc cgtgtgctca accggtccgt atacaaaagc gccatcaacc
    11221 ttatgatcaa gaacctgttg aatcaaattg tgtgtatcag ctgtgttcac tgataaatca
    11281 acttcaggaa aacgcctgag gaaggaggcc gcatgctcgg gcagatgcgt taccgctgtt
    11341 gtttccaacg atccgatccg caaaggccct ttcggatgtt gacccatctg tgccgatttt
    11401 tcagctttgt ccagcagtga taatacttgc tctgcgtatt gcaataggtt ttctccagca
    11461 gctgtcagct tcatcccgcg attcgttcga tgaaaaagtt tgatcttcaa atcttcctct
    11521 aggttatgta ttctggctgt cacattcgat tgaacataat tcagcattcg ggctgctttc
    11581 gttatacttc cttcacgggc aacagcccga aaaatcttta aatctccgct ttccacaggc
    11641 actcaccttc ttgctatgat aaaaagtgat atgagctatc atatttgttc attttactcg
    11701 aagaaaaccg ctatgtaaaa tatgtaaaga tatgaaaata caattcaatg aggaggcaga
    11761 cagcatgaaa gctgtaattc acaacggaaa aaccggactt caggggttat cctttcaaga
    11821 cgttccatca aaaaagcccg gatacggaga ggtaaaagtc aaattaaaat ctgcaggtct
    11881 aaaccatcgc gacctgtttc ttatgaataa caaatctgaa cgagatcctc atgtgatact
    11941 gggctctgac ggcgccggta tcattgaaga ggtcggtgaa ggcgtgaaaa acgttgctgt
    12001 tcaaacagaa gtaatcattt tcccgacatt gaactgggat ttgacagaga atgtgccgcc
    12061 tgttccggag attttgggcg gcccttctga cggaacgctt gctgaatacg tgatcatccc
    12121 ttcacaaaac gcaatcaaaa aaccttctta tttatcctgg gaagaagcag gcgttttgcc
    12181 tttatccgct ttaaccgcat atcgggccct gtttacaaaa gcccaattga aaaaagacga
    12241 gcatctattg atacccggca tcggcagcgg tgttgcaacc tacgctttat tcatggctaa
    12301 agcgatcggg gcgaaagtaa gtgtgacctc tcgcagtgag gagaaaagaa aaaaagcgct
    12361 gcaattaggt gctgattacg catttgacag ctacagcaat tgggatgaac agctgcaggg
    12421 agaaaaggct gatgttgttc ttgacagcat aggccccgcc ctcttttcgg aatacttccg
    12481 ccatgttaaa ccgaacggcc gtattgtcag ctttggggca agctcaggtg acgacctcag
    12541 ttttccggtg cgctctttat tctttcctca gatcaatgta ttgggaacct cgatggggag
    12601 ctgtgaagaa tttcatgata tgctcgcttt cattgaaaaa catcagctgc gccctgtact
    12661 tgaccgcact tatcctttag aaaaagcgtg tggggcatat accagaatgc aggaaggaag
    12721 acagtttggc aacatcggaa tcgtaatgga ataaaaaaaa gaaaccggct gatattcaga
    12781 ccggtttctt ttatatgata atccccttta tttacggaag aactgaactc cccatcaaat
    12841 atcgatcaac ttcgcgcgct acttcacggc cttcattaat cgcccatacg attaagcttt
    12901 ggcctcttct tgcatcccct gcggcaaata cgccatcgat atttgtttga taatccccat
    12961 atgctgcgct gattttgtta tttacagaat tgacaccgaa ctgtttcaac agcggctgtt
    13021 ctgtgccttc aaagccgata gcaataaaga caagctgagc aggccatact ttttccgtcc
    13081 cgggcagctc gcggaactcg tactttccgt gctcattttt cactttttcc atttggatgg
    13141 tatgaagctc tttcagcttt ccatttttat ccgcaaccat tttttttgtt tgaatggagt
    13201 attctcgcgg atctcttccg aattttgctt ccgcttcttc atacgcatat tcaagcgtaa
    13261 agacgtgcgg ctgttcaggc cactgattgt cattcgtgcg ggccggtgga agtttcgggt
    13321 gtttgccgaa ttggtgcaca cttttagctt tttgtcgcag agcagtagcc acgcagtcag
    13381 ctcctgtgtc tccgcccccg attacgatga catcttttcc ttttgcatca ataaacttct
    13441 tgtctttaaa gttagaatct aaatagcttt ttgttgcgag tgtcaggtag tccatcgcgt
    13501 aatggactcc ttttgaattg cgtccttcaa ttaatagatc ccgttgtttt tgtgcgcctg
    13561 tgcacagaat cacagcatca aattgctctt tcagctcatc agctgtaatg tcaacgccaa
    13621 tttctgtgtt cgtgacaaaa tcaattcctt cttgcgtcag caatttaacc cggcgttcta
    13681 caatgccttt ctcaagcttc atgttcggaa tgccgtatgt taaaaggccg cccgctctgt
    13741 ctgagcgttc aaacacagtg acggaatgcc ccgcttgatt cagctggtca gcactcgcca
    13801 gtccggccgg gcctgatcca acgatggcca cttttttgcc tgttcgtttt ttaggaatcc
    13861 taggctgaat ccagccattc tcaaatcctt tgtcgataat ggtccgttcg atatttttaa
    13921 tggatacggc cgggtctgaa atcgctaatg tacatgatcc ttcacaagga gcgggacata
    13981 cccgccctgt gaattcagga aagttgtttg ttttcaaaag gcgttccaat gcttctttcc
    14041 atctgccccg gtagacaaga tcattccatt caggaattaa gttgtaaatc ggacagccgg
    14101 atgtaaatcc gttaatgtct gcaccgatct ggcaaaacgg tgtaccgcaa tccatacacc
    14161 gcgccccctg ccgtttcgat gcttcttctg aaaaaggagc agaatattct ttccaatcct
    14221 ttaagcgagt gagagggtcc cgctcagcag gtttttctcg tttgatctcc ataaatccag
    14281 ttggtttccc catgttcctc tccccttcct tactgtacta ccgcttgttt ttgtcccgat
    14341 gacgctgtat tctgctttgg cttcgtgttg gcttcaaatg cgtacatgac agcttcttca
    14401 tcagataagc ctgcagcttt ttgctcttcg atgcttgcga gcatttgttt atagtttttc
    14461 ggaatgactt tgatgaattt tttcacgctg tcttcccact gatcaagcag gtctgtagct
    14521 ttttggctgt ttgtatacgc agcatgtttt tcaagcattg ctttgatttt ctgggtttct
    14581 ttttcatcct ctaatgattc aaataaaatc atctcaaggt tgcatttgcg tttaaacgct
    14641 tttacatctt cggccagtac ataagcgatt ccgccggaca tacctgccgc gaagtttttg
    14701 cctacatctc cgagtacgac aacacttccg ccagtcatgt attcacagcc gtggtcgcca
    14761 ataccttcta caaccacgtt cacaccgctg ttccgaacgg caaagcgttc acccgcacgt
    14821 ccgttaatat atgcttctcc gcttgtcgcg ccgtagaaag ctacgttgcc gataatgacg
    14881 ttgtcatctg aagcggaatt gaatccttcc ggtgacttga cgatgatttt tccgccagaa
    14941 agcccttttc cgacataatc atttgagtct ccgtccaaat aaagcgtcat ccctttagga
    15001 acgaaggctc caaagctttg tccggctgat ccggtaaact gcagcttgat cgtatcttca
    15061 ggaagccctt cttctccgta gcgtttcgaa atttcactgc ctgttatcgt tccggctaca
    15121 cggtttgtat tgttgatttg aatagaaaca tccgcttctt ttccagactc gatggcttct
    15181 tgtacggccg ggagaatcgc tgtaatatca agtgattgat caatcttatg attttgcggc
    15241 gattggaacg tccgtacgcc ttcaggctga taaagaagtg tagacaaatc aagctggctt
    15301 gctttccaat gcgccttcgc ccgttcactc acatgaagta cgtcagtgcg tccgatcatt
    15361 tcatcaaatg tcttgaagcc taacgcagcc atgtactcac gaacttcttc agcaatgaac
    15421 agcatatagt tcacaatatg atcaggatcg cccatgaact ttttgcgaag ctctggattt
    15481 tgtgtcgcta caccgacagg acatgtatcc aaatggcagg cacgcatcat gacacaaccg
    15541 agtacaacta acggagccgt tgcgaaaccg aattcttcgg cgccgagcaa ggcagccatc
    15601 acaacgtctc ggcccgtcat aagctttccg tctgtttcta aaacaacacg gtcacggagt
    15661 ccgttcagca ttaacgtttg atgtgcttcg gcaaggccaa gctcccacgg aagccctgta
    15721 tgtttaatac tggttttcgg agaggcacct gtacctccgt cgtaaccgct gatcacaatg
    15781 acatctgcgg tcgctttggc aacacctgca gcgattgtgc ctacgcctgc ttttgacacc
    15841 agctttacgc tgattcttgc gtcacggttg gcatttttta aatcgtggat cagctgggct
    15901 aaatcctcaa tcgaataaat gtcgtggtgc ggcggcggtg agattaatcc gacaccaggc
    15961 gttgatccgc ggacatcggc aacccaagga tataccttgt tgccaggcag ctgtccgcct
    16021 tcacccggct tagcgccttg cgccatttta atctgcagct catctgcatt aacgaggtaa
    16081 tggcttttga caccgaaacg tccggatgca atttgtttga tcgcgcttct tctgtcatcg
    16141 ccgtttttat ctggaacaaa gcgtttcgga tcttctccgc cctcaccgct gttgcttttc
    16201 ccgccaagac ggttcattgc gattgctaaa gcttcatgcg cttccttact taaggatcca
    16261 aatgacatcg cacccgtttt aaagcgtttg acaatcgatt cagcggattc aacttcctcc
    16321 aatttcagag gcttgcggtc tccgtcaaat gcgaacaagt tccgtaaaaa tccaatgcgc
    16381 tcttcatctg ccgcttttgt atattgttta aacagattgt aatcatttct tcggcacgcc
    16441 cattgcaagg tatgaatcgt ttttgggtta aacgcgtgat gctctccgcc gtttctccat
    16501 tggaagtcac ttcccggttc aagcgttttg ctgtaatcat cctgatacgc ttcccggtgg
    16561 cggcgctgcg cctcttctgc aattgtgttc aagtcgatgc cgccgagctg tgatgcagtt
    16621 cctgtgaaat agcggtcaat cacatcgcgg ctgattccta ctgcctcaaa gatttgggca
    16681 cctctgtagc tttgtacagt tgaaatcccc atcttggaca tgacttttac tacaccttca
    16741 gtaatgcttt ttccatattt gctgaccgct tcttcatagc taatatctaa acggccttca
    16801 tcaatttcct gcttgtaggt cgcataagcg agataaggat taatcgcatc cgcaccataa
    16861 ccgattaaag ctgcaaagtg atgcacttca cgcgcttctc ctgattccac aataatactg
    16921 acttttgtac gcagcccctt gcggattaaa tgctgatgca gcgcgctgac tgccagaagc
    16981 ggcggaattg gtgtcaggcg tccgttcatc tttttgtctg ataaaattaa caggcttaca
    17041 ccttggctga tggctttttc tgcctgtgtg aacatgtcct ttaatccgcg ttcaagatcc
    17101 tctgaaaaca gcacatcgat tttttggctt tttaaatcag gatgaacaat cgtttttaat
    17161 gcgtaaaact gttcattgga taaaacaggt gtatatagtt taatccggcg aacgtttcgc
    17221 tcacttgggt gaagaagatc cccttctgca cctagccaag tcatcgtaga tgtcacaagc
    17281 tgctcacgaa tcgcgtcaat tggcgggttc gtcacttgtg caaacagctg cttaaagtag
    17341 ttaaacagtg attgcgcgcg gtctgacaga acagcaagcg gggcgtcatt ccccattgaa
    17401 ccaagaggat ctttgccttc tttaatgaca ggaattaaat atttttggat atcttcatat
    17461 gtgtatccga atgccttctg acgagtaaga agatctgtaa attgttcttc ctctcttgat
    17521 tccggatcag gatttacttg gacaagctct tcctcaagcc acttttggta cgggaactct
    17581 gttgcaattt gtgttttgac ttcttcatct gagataatcc ggccttcttc caggtcgatt
    17641 aacagcattt ttccaggttc tagacggttt ttatataaaa cgttctcctg ttcaacttca
    17701 ataacgccta cttcagatga gaaaataata taatcatctt ttgttacata ataacgggcc
    17761 ggacggagac cattccggtc aaggatcgca ccgatttgtt ttccgtcagt aaatgaaatg
    17821 gctgtcggtc cgtcccaagg ctccattagg gaactatggt actcgtagaa cgctctcttt
    17881 tccttagaca tatgcgtatt ttccgtccat ggctcaggaa tgagcatcat cgctgtatgt
    17941 gccggtttgc gtccagccat tacaaaaaac tcaaatgcgt tatccaaaat ggaagagtca
    18001 ctgccgtcag cattcagaat tggaagaatc ttgttcaagt cctcaccgaa gctttcagaa
    18061 acaaattgct gctcacgcgc tctcatccag ttaatgtttc cgcgaagggt gttaatttca
    18121 ccgttgtgaa ccaaataacg gtttggatgc gctctttccc atgtagggaa tgtgttggtg
    18181 ctgaaacgtg aatggacaag cgcaaaagca gaaacgaatg cttcatcttg cagatcagaa
    18241 taaaacgcat caacttgttc aggtgttaaa aggcctttgt aaacaatggt ctggcttgaa
    18301 agactggcaa aataaaaatc aagaccttcc gttactcccc agttttcagc cagtttacga
    18361 atgacataca attttcgttc aaaagacaaa ttgtccttca gatcagaact tgcgccgata
    18421 aatacttgac ggacaaacgg acagcttttc tgtgccactg ttccgatttt tccgacattt
    18481 acaggtacag ttctccatcc aagaacggct tggccttctt gttcaatcag tgcattgatt
    18541 tgcttttcga tttttattct ttcatcttcc ttctgtgaga aaaagaccat tcctaccccg
    18601 taacgccctt tttccggcag attgatgtct ttgcactctt tcctaaagaa agcatcaggg
    18661 atttgaacca gtaagccggc tccgtctcct gtatccgggt cactgccttg acctcctctg
    18721 tggtctagct ggcaaagcat cttaagcccc tgtttgacga tgtcatgagt ctgcttgccc
    18781 tttaagtgcg catataggcc gattccgcat gcatcatgtt caaattcagg acggtagaga
    18841 ccttgagctt ttggcatttg attgtacgtc ataattcctc tcccccgatc aatttccgat
    18901 aataccggtc ataaaatctt acaactctat aatcattgta ggttttcaaa acgatataaa
    18961 caatatataa tttagatcaa aagaatctca aaatgagata gatggatgtg agacaaacat
    19021 ggagctgcgc caactgcgct attttatgga ggtggctgaa cgtgaacacg tttcagaagc
    19081 tgctgatcat ttgcatgtgg cccaatcagc aatcagcaga caaattgcaa atcttgaaga
    19141 agaattaaat gtgactttat ttgagcgtga agggagaaat atcaaactca cgccgatcgg
    19201 aaaagaattt ttgattcatg tgaaaacggc aatgaaagcc atcgattatg cgaaagaaca
    19261 aattgatgag tatctcgacc cgcatcgcgg gacggtaaag attggctttc ctacaagcct
    19321 cgccagccag cttttgccga ctgtgatttc agcatttaaa gaagaatatc cgcacgtaga
    19381 atttttgctg cgacaaggct cctataagtt tctgattgaa gctgtcagaa cccgcgatat
    19441 tgatttggcc ttattagggc cggtgccgac gaactttcct gacataacag gaaaaatttt
    19501 attcacagag aaaatttacg cgcttgttcc attaaatcat ccgcttgcca aacaaaaaac
    19561 ggttcattta atcgatttac gcaatgacca atttgttttg tttccggaag gatttgtgct
    19621 tagaaaaatg gcaattgatg cttgcaaaca agccggcttt gcccctctcg tttctacaga
    19681 gggtgaggat ttggatgcca ttaagggctt ggtgtccgcg ggaatgggcg ttacccttct
    19741 gcctgaaagc acgtttgctg aaacaacccc tcgttttact gtgaaaattc caattgagtt
    19801 ccctcaagtg aaacggactg tcggaattat taaaccgaaa aacagagagc ttgcgccgtc
    19861 tgcgaatgac ttttatgagt ttgtcattca attcttctct aagctggagc agtatcaata
    19921 aaaaaacgaa cccgagcttc tataaagaag cttcgggttt tttgctcttg tcagattaat
    19981 atacaggcaa agataaatcc acatggcaca caaatgcttc ctgatcaatt actgctttgt
    20041 tcatcagctc ttttttctta tcgagttctt gaagctgtac agaagaataa ttgacgattc
    20101 cgagcccgat ttctgcccct tgagaatcca tcagccgaac aactgatccg cttttgaatt
    20161 tccctttaat ctcctgtaca ccgtccagat ataaactcga ttgcccgttt gttatttttc
    20221 gtgaataatc atctgataaa atcatttcac cttctgggcc cgaattaaaa gcgatccact
    20281 gctctttatg gtttaacgga agcgttccct ctgcttcaaa ataggtgcct tctgcctctt
    20341 gatgaacagc tttatataga atatcttttg catctgcctg accaagaaat cctttaatgc
    20401 cagaagccat tacgatttta aacgcatcaa gcttagagcg catgccgccg gtaccgacgc
    20461 cgctgccagt atcacctgcg cacgcttcga tgtcaggcgt tatctcactc acccgctgca
    20521 tcctttttgc ttctggattt gtgcgcggat tgccgtcata taagccatca atatctgata
    20581 aaatcacaag catatccgca tcaattaatc cggcgacttt tgccgctagt gtatcattgt
    20641 cgccaaactt gagccgattg acggtaactg tgtcgttttc gtttataatt gggatgatgc
    20701 cgcgttcgag cagtacattc attgtattcc ggacattgtt atatcgatat tcatcagaaa
    20761 aatcgtttct cgtaattaaa atttgggacg caacatagcc atgcgccaaa aacagctttg
    20821 aataagcctc catcagcagg ccctggccga ttgaagctga tgcctgtttt tctggaagct
    20881 tctcgggtct ttggataaat ccgagcttcc gatatcctgc cgccactgcg cctgaagaga
    20941 ccaaaatcac ttcatagccg gcgtctttaa gtttggcgat ctggtcgacc aacgcttcta
    21001 attttcgaat gctgatttct ccatgaaggc ttgttaatga actgctccca attttcacaa
    21061 cgactctttt catgttagta tcggacgtca ctttatcact cctgatagcg gggcagctgt
    21121 tttttcgata tcgtcgctga tttcctttga acgcatagcc gcatgcttga tcgcttgaga
    21181 aatggcttct ccgccgccgc tctttttcaa ggcttgcagc ccggcagctg tcgttccgtt
    21241 cggtgacgtg atattgtccc ttaagacctc aggctgttcg cctgtttcca tgagcatttt
    21301 tgcggcaccc aaaagcgtct gtgctccgat gcttcgagat aactgtttat cgagtcctgc
    21361 ttcctcgcct gtcttctcaa tgaattccat taaataataa aaatacgcgg ggccgctgcc
    21421 ggcaattccg gtgaaaatgt ccatttgatt ttcttgaatt gtatagactt cacccatgca
    21481 tccgagcaat gcttcggcca gctttttcag gtcttttgac acatacttgc caagcgcaat
    21541 ggccgttgca gaagcgccaa tcatactgga tgtgttgggc atcactctga caaccggctg
    21601 ttcattaagc aatgattgtt caatataaga ggtggttatg ccggcaagga ccgacaatat
    21661 taattgatgg ggttgaatac gtgattttag tgatgacaga gcgctttcag cgtcttttgg
    21721 cttcattgcc aaaatgagta catccatgtc ttcaatacaa agttcattgg gcgtagcgcc
    21781 agtaattcca tattgaagtt caagttcagc taatcgctct gtattgctgc ggtttgtaac
    21841 gcagatgttt tgtttcggga ttttgttggc acgaacgata cctgatatca ttccttccgc
    21901 catagatcct gctcctataa aggctacttt cttttgatca aagatcggta acatctcctt
    21961 tgttcgcttt tttgttcgca ttttcacacg tttaaaatgt taccacgtga ggaaatgatg
    22021 tcaagtttga aggtcatcat tgatttgtat tgtttctttt cgacaaatat gtataatgaa
    22081 aagcagaaaa cacccgatgc atactgctgt gccgggt
//
