LOCUS       NZ_JALAUL010000021     13811 bp    DNA     linear   CON 26-JAN-2024
DEFINITION  Bacillus atrophaeus strain CK4F1-2 Contig_0000021, whole genome
            shotgun sequence.
ACCESSION   NZ_JALAUL010000021
VERSION     NZ_JALAUL010000021.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus atrophaeus
  ORGANISM  Bacillus atrophaeus
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 13811)
  AUTHORS   Dunlap,C.
  TITLE     Crop Bioprotection Bacillus Genome Sequencing
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 13811)
  AUTHORS   Dunlap,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-FEB-2022) CBP, USDA-ARS-NCAUR, 1815 N. University St.,
            Peoria, IL 61604, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC NGS Cell v. 21
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 219.01779805621194x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/24/2024 02:32:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,147
            CDSs (total)                      :: 4,069
            Genes (coding)                    :: 3,904
            CDSs (with protein)               :: 3,904
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 165
            CDSs (without protein)            :: 165
            Pseudo Genes (ambiguous residues) :: 0 of 165
            Pseudo Genes (frameshifted)       :: 97 of 165
            Pseudo Genes (incomplete)         :: 106 of 165
            Pseudo Genes (internal stop)      :: 39 of 165
            Pseudo Genes (multiple problems)  :: 66 of 165
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:35:49
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 13811
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JALAUL010000021.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..13811
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     gene            <1..4041
                     /locus_tag="MOE42_RS20685"
                     /old_locus_tag="MOE42_20630"
     CDS             <1..4041
                     /NRPS_PKS="Domain: AMP-binding (285-692). E-value:
                     6.4e-102. Score: 333.1. Matches aSDomain:
                     nrpspksdomains_MOE42_RS20685_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (797-861). E-value: 6.2e-22. Score:
                     69.6. Matches aSDomain: nrpspksdomains_MOE42_RS20685_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (873-1183). E-value:
                     4.1e-147. Score: 483.0. Matches aSDomain:
                     nrpspksdomains_MOE42_RS20685_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (1191-1338). E-value: 5.5e-44.
                     Score: 141.7. Matches aSDomain:
                     nrpspksdomains_MOE42_RS20685_TIGR01720.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019846737.1"
                     /locus_tag="MOE42_RS20685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE42_20630"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_268487133.1"
                     /sec_met_domain="AMP-binding (E-value: 3.7e-112, bitscore:
                     362.5, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.8e-16, bitscore:
                     47.6, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 2e-82, bitscore:
                     264.2, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="FKKGDTYEKQESYWLKQLGGELPVLELPADKPRPAVRSFAGDKIS
                     FTLDQEVTSGLNRLARENGSTLYMVLLAAYSALLARLSGQEEIVVGSPIAGRPHEDLEP
                     VLGMFVNTLALRTRPEGGKGFTDYLQEVRQTALEAYEQQDYPFEELVEKLGVQRDMSRN
                     PLFDAMFILQNMEQHDIHLPEIEVRRNSLIHSISVFDLTLSAVESGGQIECEMEFSTDV
                     FLKDTVERWSSHLIELLRSVTTRPDTVLARLEILEQQEKRMIAEGFNDTQIEFSQSADL
                     FHHIFEAKTEETPHHIAIIEGEKQITYRQLNERANRLARTLRRKGTGPNYTVAILANRS
                     IDAVVSILAVLKSGGTYIPIDTHYPEGRIRHLLQDSGALTLLVQQDLKHLIADLTGIGV
                     SQIFYLDDEYLYDSDASNLIPAAGPEDAAYIIYTSGTTGTPKGVVIKNRSFTHAALAWR
                     EIYQLERFPVRLLQMASFSFDVFSGDLARTLLNGGTLVICPDEVRLEPAELYALLIQQR
                     ITLMESTPALMVPFMDYVYRSNLSLPDLRLLVLGSDTIKAQDFKTLSQRFGKQMRLINS
                     YGVTEATIDSSYYEANMGAAVNEEYVPIGVPLPNVHMYVLSNYDQIQPIGVAGELCIGG
                     AGVAKGYHGKPELTEAKFTEHPFISDEKIYRTGDQACWLPDGTVRFLGRMDNQVKIKGY
                     RIEAGEIESVLLQTGMVKEAAAAVQKDTQGQSYLAAYIVPSDVDTSALRDALAKELPAY
                     MVPSHFMALDKIPLTPNGKVDRKALPVPNEGLRQTYTAPYTDKQTMMAGIWEDVLSISR
                     VGIHDSFFDLGGDSIKALQVSARLAAEGWKMTIRDLFQFPTIQKLTDHIIPAVSAADQG
                     PVEGKAVLTPIQRRFFSQPDAFRYHYNQSVVLFNEIGFRDDALRQALRRLAVHHDVLRM
                     VFTKDQAGRIIQHNRGTGLQDEELYHLHITDWTKEPQALIHAEEQIAKEEARIQKAMRL
                     EQGPLLQAGLFKTADGDYLLIAIHHLVVDGVSWRILLEDLSAAYQHVLEGREIKLPPKS
                     DSYLSYANALVQSAESRKLLQEKPYWESVINAQTAVLPKDQPYASEGLQKNAGTASLIL
                     SGDWTSKLLFETQQAYGTDVNELLLTGLGMALAEWTGNEQIVISTEGHGREGHVSDIDI
                     SRTVGWFTSVYPVLLNMDANHSDDKLASRIKATKDMLRRVPNQGTGYGLLEYMTENEDW
                     NREPEVSFNYLGQFNDIEDSKTLRMSSYQPRYEIAGERYREYALDINAMIIGGQLQVKA
                     VYTQVFHHRTIELFMESFRKHIICAIEHCSGKKEREKTLSDFSNKEMTSAALSSIANLV
                     KDL"
     source          1..13811
                     /db_xref="taxon:1452"
                     /isolation_source="soil"
                     /mol_type="genomic DNA"
                     /organism="Bacillus atrophaeus"
                     /strain="CK4F1-2"
                     /submitter_seqid="Contig_0000021"
     cand_cluster    1..13811
                     /SMILES="NC(CCCN)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(C(O)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..13811
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<0:>13811](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      <1..>13811
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     CDS_motif       199..252
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20685_0001"
                     /evalue="1.00E-02"
                     /label="Cy4"
                     /locus_tag="MOE42_RS20685"
                     /protein_end="83"
                     /protein_start="65"
                     /score="9.0"
                     /tool="antismash"
                     /translation="TLYMVLLAAYSALLARLS"
     CDS_motif       262..351
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20685_0002"
                     /evalue="1.00E-15"
                     /label="C5_LCL_267-296"
                     /locus_tag="MOE42_RS20685"
                     /protein_end="116"
                     /protein_start="86"
                     /score="50.0"
                     /tool="antismash"
                     /translation="EIVVGSPIAGRPHEDLEPVLGMFVNTLALR"
     CDS_motif       400..519
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20685_0003"
                     /evalue="6.40E-22"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="MOE42_RS20685"
                     /protein_end="172"
                     /protein_start="132"
                     /score="70.0"
                     /tool="antismash"
                     /translation="RQTALEAYEQQDYPFEELVEKLGVQRDMSRNPLFDAMFIL"
     aSDomain        859..2079
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE42_RS20685_AMP-binding.1"
                     /evalue="6.40E-102"
                     /label="MOE42_RS20685_AMP-binding.1"
                     /locus_tag="MOE42_RS20685"
                     /protein_end="692"
                     /protein_start="285"
                     /score="333.1"
                     /specificity="substrate consensus: Orn"
                     /tool="antismash"
                     /translation="FEAKTEETPHHIAIIEGEKQITYRQLNERANRLARTLRRKGTGPN
                     YTVAILANRSIDAVVSILAVLKSGGTYIPIDTHYPEGRIRHLLQDSGALTLLVQQDLKH
                     LIADLTGIGVSQIFYLDDEYLYDSDASNLIPAAGPEDAAYIIYTSGTTGTPKGVVIKNR
                     SFTHAALAWREIYQLERFPVRLLQMASFSFDVFSGDLARTLLNGGTLVICPDEVRLEPA
                     ELYALLIQQRITLMESTPALMVPFMDYVYRSNLSLPDLRLLVLGSDTIKAQDFKTLSQR
                     FGKQMRLINSYGVTEATIDSSYYEANMGAAVNEEYVPIGVPLPNVHMYVLSNYDQIQPI
                     GVAGELCIGGAGVAKGYHGKPELTEAKFTEHPFISDEKIYRTGDQACWLPDGTVRFLGR
                     MDNQVKIK"
     aSModule        859..4017
                     /complete
                     /domains="nrpspksdomains_MOE42_RS20685_AMP-binding.1"
                     /domains="nrpspksdomains_MOE42_RS20685_PCP.1"
                     /domains="nrpspksdomains_MOE42_RS20685_Epimerization.1"
                     /domains="nrpspksdomains_MOE42_RS20685_TIGR01720.1"
                     /locus_tags="MOE42_RS20685"
                     /monomer_pairings="Orn -> D-Orn"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       1045..1086
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20685_0004"
                     /evalue="4.20E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="MOE42_RS20685"
                     /protein_end="361"
                     /protein_start="347"
                     /score="13.7"
                     /tool="antismash"
                     /translation="LAVLKSGGTYIPID"
     CDS_motif       1285..1341
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20685_0005"
                     /evalue="2.50E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="MOE42_RS20685"
                     /protein_end="446"
                     /protein_start="427"
                     /score="29.2"
                     /tool="antismash"
                     /translation="AYIIYTSGTTGTPKGVVIK"
     CDS_motif       1873..1962
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20685_0006"
                     /evalue="6.40E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="MOE42_RS20685"
                     /protein_end="653"
                     /protein_start="623"
                     /score="50.4"
                     /tool="antismash"
                     /translation="PIGVAGELCIGGAGVAKGYHGKPELTEAKF"
     CDS_motif       2044..2109
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20685_0007"
                     /evalue="1.10E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="MOE42_RS20685"
                     /protein_end="702"
                     /protein_start="680"
                     /score="33.5"
                     /tool="antismash"
                     /translation="FLGRMDNQVKIKGYRIEAGEIE"
     aSDomain        2395..2586
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE42_RS20685_PCP.1"
                     /evalue="6.20E-22"
                     /label="MOE42_RS20685_PCP.1"
                     /locus_tag="MOE42_RS20685"
                     /protein_end="861"
                     /protein_start="797"
                     /score="69.6"
                     /tool="antismash"
                     /translation="TMMAGIWEDVLSISRVGIHDSFFDLGGDSIKALQVSARLAAEGWK
                     MTIRDLFQFPTIQKLTDHI"
     aSDomain        2623..3552
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE42_RS20685_Epimerization.1"
                     /evalue="4.10E-147"
                     /label="MOE42_RS20685_Epimerization.1"
                     /locus_tag="MOE42_RS20685"
                     /protein_end="1183"
                     /protein_start="873"
                     /score="483.0"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLVVDG"
                     /tool="antismash"
                     /translation="EGKAVLTPIQRRFFSQPDAFRYHYNQSVVLFNEIGFRDDALRQAL
                     RRLAVHHDVLRMVFTKDQAGRIIQHNRGTGLQDEELYHLHITDWTKEPQALIHAEEQIA
                     KEEARIQKAMRLEQGPLLQAGLFKTADGDYLLIAIHHLVVDGVSWRILLEDLSAAYQHV
                     LEGREIKLPPKSDSYLSYANALVQSAESRKLLQEKPYWESVINAQTAVLPKDQPYASEG
                     LQKNAGTASLILSGDWTSKLLFETQQAYGTDVNELLLTGLGMALAEWTGNEQIVISTEG
                     HGREGHVSDIDISRTVGWFTSVYPVLLNM"
     CDS_motif       2638..2664
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20685_0008"
                     /evalue="4.40E-03"
                     /label="NRPS-E1"
                     /locus_tag="MOE42_RS20685"
                     /protein_end="887"
                     /protein_start="878"
                     /score="10.3"
                     /tool="antismash"
                     /translation="LTPIQRRFF"
     CDS_motif       2737..2799
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20685_0009"
                     /evalue="2.50E-04"
                     /label="C2_LCL_024-062"
                     /locus_tag="MOE42_RS20685"
                     /protein_end="932"
                     /protein_start="911"
                     /score="13.5"
                     /tool="antismash"
                     /translation="DALRQALRRLAVHHDVLRMVF"
     CDS_motif       3025..3090
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20685_0010"
                     /evalue="6.00E-12"
                     /label="NRPS-E2"
                     /locus_tag="MOE42_RS20685"
                     /protein_end="1029"
                     /protein_start="1007"
                     /score="37.6"
                     /tool="antismash"
                     /translation="LLIAIHHLVVDGVSWRILLEDL"
     CDS_motif       3391..3432
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20685_0011"
                     /evalue="2.20E+01"
                     /label="Cy4"
                     /locus_tag="MOE42_RS20685"
                     /protein_end="1143"
                     /protein_start="1129"
                     /score="-1.4"
                     /tool="antismash"
                     /translation="LLLTGLGMALAEWT"
     CDS_motif       3496..3546
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20685_0012"
                     /evalue="3.80E-09"
                     /label="NRPS-E5"
                     /locus_tag="MOE42_RS20685"
                     /protein_end="1181"
                     /protein_start="1164"
                     /score="28.4"
                     /tool="antismash"
                     /translation="DISRTVGWFTSVYPVLL"
     aSDomain        3577..4017
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE42_RS20685_TIGR01720.1"
                     /evalue="5.50E-44"
                     /label="MOE42_RS20685_TIGR01720.1"
                     /locus_tag="MOE42_RS20685"
                     /protein_end="1338"
                     /protein_start="1191"
                     /score="141.7"
                     /tool="antismash"
                     /translation="LASRIKATKDMLRRVPNQGTGYGLLEYMTENEDWNREPEVSFNYL
                     GQFNDIEDSKTLRMSSYQPRYEIAGERYREYALDINAMIIGGQLQVKAVYTQVFHHRTI
                     ELFMESFRKHIICAIEHCSGKKEREKTLSDFSNKEMTSAALSS"
     CDS_motif       3598..3660
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20685_0013"
                     /evalue="2.30E-08"
                     /label="NRPS-E6"
                     /locus_tag="MOE42_RS20685"
                     /protein_end="1219"
                     /protein_start="1198"
                     /score="26.3"
                     /tool="antismash"
                     /translation="TKDMLRRVPNQGTGYGLLEYM"
     aSDomain        4065..4154
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE42_RS20690_NRPS-COM_Nterm.1"
                     /evalue="2.70E-16"
                     /label="MOE42_RS20690_NRPS-COM_Nterm.1"
                     /locus_tag="MOE42_RS20690"
                     /protein_end="30"
                     /protein_start="0"
                     /score="50.5"
                     /tool="antismash"
                     /translation="MTQATGIQDIYPLSYMQEGMLFHSLLHGDS"
     gene            4065..11798
                     /locus_tag="MOE42_RS20690"
                     /old_locus_tag="MOE42_20635"
     CDS             4065..11798
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (0-30). E-value: 2.7e-16.
                     Score: 50.5. Matches aSDomain:
                     nrpspksdomains_MOE42_RS20690_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (7-309). E-value:
                     7.4e-109. Score: 355.4. Matches aSDomain:
                     nrpspksdomains_MOE42_RS20690_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (474-867). E-value:
                     1.2e-110. Score: 361.8. Matches aSDomain:
                     nrpspksdomains_MOE42_RS20690_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (974-1042). E-value: 1.3e-22. Score:
                     71.7. Matches aSDomain: nrpspksdomains_MOE42_RS20690_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1058-1344). E-value:
                     3.6e-105. Score: 343.2. Matches aSDomain:
                     nrpspksdomains_MOE42_RS20690_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1508-1905). E-value:
                     4.9e-116. Score: 379.6. Matches aSDomain:
                     nrpspksdomains_MOE42_RS20690_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2013-2079). E-value: 2.4e-21.
                     Score: 67.7. Matches aSDomain:
                     nrpspksdomains_MOE42_RS20690_PCP.2"
                     /NRPS_PKS="Domain: Epimerization (2091-2407). E-value:
                     3.9e-147. Score: 483.1. Matches aSDomain:
                     nrpspksdomains_MOE42_RS20690_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (2417-2570). E-value: 7.3e-50.
                     Score: 160.8. Matches aSDomain:
                     nrpspksdomains_MOE42_RS20690_TIGR01720.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003242403.1"
                     /locus_tag="MOE42_RS20690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE42_20635"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_268487134.1"
                     /sec_met_domain="Condensation (E-value: 2e-90, bitscore:
                     290.6, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 8.7e-123, bitscore:
                     397.5, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.6e-17, bitscore:
                     51.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQATGIQDIYPLSYMQEGMLFHSLLHGDSKAYVEQTSFTINGNL
                     CINSFQKSLNLLVSRYDIFRTIFIKEVPDLSGPQQVVLTSRELTVKKEDISGMKIKEQH
                     IFIEEYKKKDREKGFDLQKDPLMRLTLFDMGENRHTCVWTHHHIIMDGWCLGIVLKEFF
                     HIYYSLKNSDPLQLGSTVPYSRYIGWLGEQDKEETGVYWDGYLSDYGQTASIPLTNNRR
                     KDGVYVSEQIHFSLDPSSVEKLTALSRSLGVTLNTLFMSIWGVMLHRYNATDDAVFGSV
                     ISGRPSTIDGIESMVGLFINTIPVRVRAHGGMSFSSLVKEVQKDTLASENHGYYPLYEI
                     QNRSPLKQGLLNHILVFENYPVQIQKAVGTWQDQEENALKLGDFSMSEETNYDLNVVIV
                     PGDNFYIKFSYNASVYKQEDMLRIQGHLKKALDCILSDPDIAVENIDIVPVEEQMLIHT
                     FNKTDRPYPEKTVYELFEDQAAETPEATALVLDDTHWTYRQLDERANQMARVLKEKGAK
                     PGSIVAVMMRRSKEMAAALLGIWKAGSAYMPLDPGYPSERLSFLLDDSETSLLLTEDEL
                     ISTVPSDYAGDTVTTEEALSYKTDPLPTTIQAGKLAYLIYTSGTTGRPKGVLVDHRGIA
                     NTLQWRREEYGMSGQDTALHLFSYVFDGCVTSLFTPLLSGACVILTNDDDAKDVLAIKK
                     TIAKHRVTHLLIVPSLHRVLLEVLEKEEAKTLRVVTFAGEPVTADLLEASREICPHTEL
                     ANEYGPTENSVATTVLRHLNQESCITIGRPIANTEVCILIGNQLQPIGALGELCIGGAG
                     LAQGYYKQTELSQKAFTSHPFREGERLYRTGDAARWLQDGTLEYIGRFDDQVKIRGYRI
                     ELGEVEAVLRNIPGVKEAAVVARETSSDERELFAYIVPQKGEGLPDVHLHLAGKLPAYM
                     IPASITKINKMPLTSSGKLDRSALPEPMNMADSAHTYEPPRTIIESELTAIWKNVLNKK
                     QIGIRDDFFHLGGQSLKAATLVSRIHKKLNIQLPLSEVFIYPTVESMAAKIESLKEQTF
                     TTIAPAQSRELYPLSFSQKRMYTLHQLEENGTGYNMPAALELHGKLDRQRLKQAVTELV
                     NRHESLRTSFVIHNGEPMQQVHVSLTPEFTELQIESKSQLKQTMQSFIQPFVLTNAPLL
                     RACLIVLENDHHYLLLDMHHIAADGVSMSTLIQEFTDLYCGKTLHPLKLQYKDFAVWQK
                     EQFARQLFSKQEDYWLKQLSGLPVLELPLDKNRPLLPDFSGGTFEAEIDRETAERLHRI
                     MSETGCTLYMVLLAAYSILLSKLSGQKDIVVGSPAAGRRHADLEPVIGLFVNTLAMRSQ
                     PEGEKSFRSYLQEIKEVALTAYEHQDFPFEKLTNKLGTQRELNRNPLFDAMLVLQSSED
                     FQLELPGLAISSRKLPHEASKFDLTLHAEENKEGIRCCFEYSTALFEHETVARWANHFK
                     ELLRSITADTDVKLADMQMLGGSEQRMLLDNMHHLSDYPRNKSLPDLFENWAKETPEHI
                     AVVMDDHRLTYRELNDQAERAAAMLMKKGVRSEQIVGLMTERSPDMLIGILAILKAGGA
                     YLPIDPDYPQERINFMLHDSGAEMLLTHTAKERPDGYQGEILYIEDAENEPPSDVQKPS
                     VRAEQPAYIIYTSGTTGQPKGVAVEHRNVVSLLKHKELPFDFGPQDVWTLFHSYCFDFS
                     VWEMFGALLNGGTLVVVSKEIARDPNAYRLLLKEEGVTVLNQTPTAFYSLMHEEQSHAD
                     ALSVRYVIFGGEALQPGMLRSWKGKYPETDLINMYGITETTVHVTYKKLADIDIAANKS
                     NIGKPLATLTAYVLDDYMNFQPIGIPGELYVGGAGVAKGYVNREELTAARFIPNPYVPG
                     DRLYRTGDIAKRLPNGELEYEGRIDNQVKVRGHRIELGEIKAALLKHSLIKEAAVITRL
                     DEQGQHTIYAYLISETDRKLNQSKIRASLKAVLPDYMIPARFMQLDSMPLTSNGKLDQK
                     ALPEPDAGTRISDDILPRNDTEKVMAEIWEELLGLEQLGVSANFFELGGDSIKALQVCA
                     RLKQHGFETTVRELFEHQTLGELSASVRKIERVIDQAPVSGEMPWTPVQHWLFSQSMTS
                     VHHFNQSVMLYRADRFNSSALREVLKSLVKHHDALRIVCRNIESKPVQVNRGIDLTDEE
                     LYFFQQFDIRDDHAKATDHPAGLSSEEKRRIAETADRIQQNIQLETGPLLHAGLFRASD
                     GDHLLLAIHHLVIDGVSWRILFEDFEIGYEQALAGKPIVFPQKTDSFHDYAHQLAAYSD
                     SRGLFREIEYWTEREKQHVERLPRDYTVSSNKLKDTNVIDFELSRQNTEQLLTSVNKAY
                     TTDTNDILLAALGLSLQEWTGYDHLKISMEGHGRESYLDNIDLSRTVGWFTSIYPVLLD
                     MDVSEHTDEKERLGYHIKRTKDMMRRIPHKGVGYGVLKYVSGIWNETGNISNSPEISFN
                     YLGQFDQDIQMNSFEVSPVQTGDEISPDWERPYILDISGAVSSGCLKMHIVYNRYQYEA
                     QTIQTFAGHFKRILEDIIRHCAAKENREWSAADFSDEELTLEDLSEIMGAVNKL"
     aSDomain        4086..4991
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE42_RS20690_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="7.40E-109"
                     /label="MOE42_RS20690_Condensation_DCL.1"
                     /locus_tag="MOE42_RS20690"
                     /protein_end="309"
                     /protein_start="7"
                     /score="355.4"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIIMDG"
                     /tool="antismash"
                     /translation="QDIYPLSYMQEGMLFHSLLHGDSKAYVEQTSFTINGNLCINSFQK
                     SLNLLVSRYDIFRTIFIKEVPDLSGPQQVVLTSRELTVKKEDISGMKIKEQHIFIEEYK
                     KKDREKGFDLQKDPLMRLTLFDMGENRHTCVWTHHHIIMDGWCLGIVLKEFFHIYYSLK
                     NSDPLQLGSTVPYSRYIGWLGEQDKEETGVYWDGYLSDYGQTASIPLTNNRRKDGVYVS
                     EQIHFSLDPSSVEKLTALSRSLGVTLNTLFMSIWGVMLHRYNATDDAVFGSVISGRPST
                     IDGIESMVGLFINTIPVRVRA"
     aSModule        4086..7190
                     /complete
                     /domains="nrpspksdomains_MOE42_RS20690_Condensation_DCL.1"
                     /domains="nrpspksdomains_MOE42_RS20690_AMP-binding.1"
                     /domains="nrpspksdomains_MOE42_RS20690_PCP.1"
                     /locus_tags="MOE42_RS20690"
                     /monomer_pairings="Tyr -> Tyr"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       4095..4136
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20690_0001"
                     /evalue="1.30E-04"
                     /label="C1_DCL_004-017"
                     /locus_tag="MOE42_RS20690"
                     /protein_end="24"
                     /protein_start="10"
                     /score="14.1"
                     /tool="antismash"
                     /translation="YPLSYMQEGMLFHS"
     CDS_motif       4158..4271
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20690_0002"
                     /evalue="6.10E-13"
                     /label="C2_DCL_024-062"
                     /locus_tag="MOE42_RS20690"
                     /protein_end="69"
                     /protein_start="31"
                     /score="41.0"
                     /tool="antismash"
                     /translation="AYVEQTSFTINGNLCINSFQKSLNLLVSRYDIFRTIFI"
     CDS_motif       4497..4562
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20690_0003"
                     /evalue="1.20E-11"
                     /label="C3_DCL_135-156"
                     /locus_tag="MOE42_RS20690"
                     /protein_end="166"
                     /protein_start="144"
                     /score="37.0"
                     /tool="antismash"
                     /translation="HHHIIMDGWCLGIVLKEFFHIY"
     CDS_motif       4887..4982
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20690_0004"
                     /evalue="8.00E-19"
                     /label="C5_DCL_263-294"
                     /locus_tag="MOE42_RS20690"
                     /protein_end="306"
                     /protein_start="274"
                     /score="60.0"
                     /tool="antismash"
                     /translation="DAVFGSVISGRPSTIDGIESMVGLFINTIPVR"
     CDS_motif       5031..5147
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20690_0005"
                     /evalue="2.30E-18"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="MOE42_RS20690"
                     /protein_end="361"
                     /protein_start="322"
                     /score="58.6"
                     /tool="antismash"
                     /translation="QKDTLASENHGYYPLYEIQNRSPLKQGLLNHILVFENYP"
     aSDomain        5487..6665
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE42_RS20690_AMP-binding.1"
                     /evalue="1.20E-110"
                     /label="MOE42_RS20690_AMP-binding.1"
                     /locus_tag="MOE42_RS20690"
                     /protein_end="867"
                     /protein_start="474"
                     /score="361.8"
                     /specificity="substrate consensus: Tyr"
                     /tool="antismash"
                     /translation="FEDQAAETPEATALVLDDTHWTYRQLDERANQMARVLKEKGAKPG
                     SIVAVMMRRSKEMAAALLGIWKAGSAYMPLDPGYPSERLSFLLDDSETSLLLTEDELIS
                     TVPSDYAGDTVTTEEALSYKTDPLPTTIQAGKLAYLIYTSGTTGRPKGVLVDHRGIANT
                     LQWRREEYGMSGQDTALHLFSYVFDGCVTSLFTPLLSGACVILTNDDDAKDVLAIKKTI
                     AKHRVTHLLIVPSLHRVLLEVLEKEEAKTLRVVTFAGEPVTADLLEASREICPHTELAN
                     EYGPTENSVATTVLRHLNQESCITIGRPIANTEVCILIGNQLQPIGALGELCIGGAGLA
                     QGYYKQTELSQKAFTSHPFREGERLYRTGDAARWLQDGTLEYIGRFDDQVKIR"
     CDS_motif       5673..5714
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20690_0006"
                     /evalue="6.30E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="MOE42_RS20690"
                     /protein_end="550"
                     /protein_start="536"
                     /score="13.2"
                     /tool="antismash"
                     /translation="LGIWKAGSAYMPLD"
     CDS_motif       5898..5957
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20690_0007"
                     /evalue="1.60E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="MOE42_RS20690"
                     /protein_end="631"
                     /protein_start="611"
                     /score="29.7"
                     /tool="antismash"
                     /translation="AYLIYTSGTTGRPKGVLVDH"
     CDS_motif       6459..6548
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20690_0008"
                     /evalue="6.60E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="MOE42_RS20690"
                     /protein_end="828"
                     /protein_start="798"
                     /score="37.6"
                     /tool="antismash"
                     /translation="PIGALGELCIGGAGLAQGYYKQTELSQKAF"
     CDS_motif       6630..6695
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20690_0009"
                     /evalue="6.30E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="MOE42_RS20690"
                     /protein_end="877"
                     /protein_start="855"
                     /score="37.4"
                     /tool="antismash"
                     /translation="YIGRFDDQVKIRGYRIELGEVE"
     CDS_motif       6903..6929
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20690_0010"
                     /evalue="7.10E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="MOE42_RS20690"
                     /protein_end="955"
                     /protein_start="946"
                     /score="3.4"
                     /tool="antismash"
                     /translation="GKLDRSALP"
     aSDomain        6987..7190
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE42_RS20690_PCP.1"
                     /evalue="1.30E-22"
                     /label="MOE42_RS20690_PCP.1"
                     /locus_tag="MOE42_RS20690"
                     /protein_end="1042"
                     /protein_start="974"
                     /score="71.7"
                     /tool="antismash"
                     /translation="ESELTAIWKNVLNKKQIGIRDDFFHLGGQSLKAATLVSRIHKKLN
                     IQLPLSEVFIYPTVESMAAKIES"
     aSDomain        7239..8096
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE42_RS20690_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="3.60E-105"
                     /label="MOE42_RS20690_Condensation_LCL.1"
                     /locus_tag="MOE42_RS20690"
                     /protein_end="1344"
                     /protein_start="1058"
                     /score="343.2"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIAADG"
                     /tool="antismash"
                     /translation="LYPLSFSQKRMYTLHQLEENGTGYNMPAALELHGKLDRQRLKQAV
                     TELVNRHESLRTSFVIHNGEPMQQVHVSLTPEFTELQIESKSQLKQTMQSFIQPFVLTN
                     APLLRACLIVLENDHHYLLLDMHHIAADGVSMSTLIQEFTDLYCGKTLHPLKLQYKDFA
                     VWQKEQFARQLFSKQEDYWLKQLSGLPVLELPLDKNRPLLPDFSGGTFEAEIDRETAER
                     LHRIMSETGCTLYMVLLAAYSILLSKLSGQKDIVVGSPAAGRRHADLEPVIGLFVNTLA
                     MRSQP"
     aSModule        7239..11774
                     /complete
                     /domains="nrpspksdomains_MOE42_RS20690_Condensation_LCL.1"
                     /domains="nrpspksdomains_MOE42_RS20690_AMP-binding.2"
                     /domains="nrpspksdomains_MOE42_RS20690_PCP.2"
                     /domains="nrpspksdomains_MOE42_RS20690_Epimerization.1"
                     /domains="nrpspksdomains_MOE42_RS20690_TIGR01720.1"
                     /locus_tags="MOE42_RS20690"
                     /monomer_pairings="Thr -> D-Thr"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       7308..7418
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20690_0011"
                     /evalue="2.30E-18"
                     /label="C2_LCL_024-062"
                     /locus_tag="MOE42_RS20690"
                     /protein_end="1118"
                     /protein_start="1081"
                     /score="58.6"
                     /tool="antismash"
                     /translation="YNMPAALELHGKLDRQRLKQAVTELVNRHESLRTSFV"
     CDS_motif       7614..7679
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20690_0012"
                     /evalue="3.40E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="MOE42_RS20690"
                     /protein_end="1205"
                     /protein_start="1183"
                     /score="29.2"
                     /tool="antismash"
                     /translation="MHHIAADGVSMSTLIQEFTDLY"
     CDS_motif       7710..7745
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20690_0013"
                     /evalue="8.50E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="MOE42_RS20690"
                     /protein_end="1227"
                     /protein_start="1215"
                     /score="15.2"
                     /tool="antismash"
                     /translation="QYKDFAVWQKEQ"
     CDS_motif       7998..8087
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20690_0014"
                     /evalue="1.70E-15"
                     /label="C5_LCL_267-296"
                     /locus_tag="MOE42_RS20690"
                     /protein_end="1341"
                     /protein_start="1311"
                     /score="49.3"
                     /tool="antismash"
                     /translation="DIVVGSPAAGRRHADLEPVIGLFVNTLAMR"
     CDS_motif       8136..8255
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20690_0015"
                     /evalue="6.30E-16"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="MOE42_RS20690"
                     /protein_end="1397"
                     /protein_start="1357"
                     /score="50.7"
                     /tool="antismash"
                     /translation="KEVALTAYEHQDFPFEKLTNKLGTQRELNRNPLFDAMLVL"
     aSDomain        8589..9779
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE42_RS20690_AMP-binding.2"
                     /evalue="4.90E-116"
                     /label="MOE42_RS20690_AMP-binding.2"
                     /locus_tag="MOE42_RS20690"
                     /protein_end="1905"
                     /protein_start="1508"
                     /score="379.6"
                     /specificity="substrate consensus: Thr"
                     /tool="antismash"
                     /translation="FENWAKETPEHIAVVMDDHRLTYRELNDQAERAAAMLMKKGVRSE
                     QIVGLMTERSPDMLIGILAILKAGGAYLPIDPDYPQERINFMLHDSGAEMLLTHTAKER
                     PDGYQGEILYIEDAENEPPSDVQKPSVRAEQPAYIIYTSGTTGQPKGVAVEHRNVVSLL
                     KHKELPFDFGPQDVWTLFHSYCFDFSVWEMFGALLNGGTLVVVSKEIARDPNAYRLLLK
                     EEGVTVLNQTPTAFYSLMHEEQSHADALSVRYVIFGGEALQPGMLRSWKGKYPETDLIN
                     MYGITETTVHVTYKKLADIDIAANKSNIGKPLATLTAYVLDDYMNFQPIGIPGELYVGG
                     AGVAKGYVNREELTAARFIPNPYVPGDRLYRTGDIAKRLPNGELEYEGRIDNQVKVR"
     CDS_motif       8775..8816
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20690_0016"
                     /evalue="2.20E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="MOE42_RS20690"
                     /protein_end="1584"
                     /protein_start="1570"
                     /score="17.6"
                     /tool="antismash"
                     /translation="LAILKAGGAYLPID"
     CDS_motif       8997..9056
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20690_0017"
                     /evalue="3.90E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="MOE42_RS20690"
                     /protein_end="1664"
                     /protein_start="1644"
                     /score="31.6"
                     /tool="antismash"
                     /translation="AYIIYTSGTTGQPKGVAVEH"
     CDS_motif       9573..9662
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20690_0018"
                     /evalue="7.00E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="MOE42_RS20690"
                     /protein_end="1866"
                     /protein_start="1836"
                     /score="50.3"
                     /tool="antismash"
                     /translation="PIGIPGELYVGGAGVAKGYVNREELTAARF"
     CDS_motif       9747..9806
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20690_0019"
                     /evalue="3.80E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="MOE42_RS20690"
                     /protein_end="1914"
                     /protein_start="1894"
                     /score="31.9"
                     /tool="antismash"
                     /translation="EGRIDNQVKVRGHRIELGEI"
     CDS_motif       10023..10049
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20690_0020"
                     /evalue="2.90E+00"
                     /label="NRPS-A_a10"
                     /locus_tag="MOE42_RS20690"
                     /protein_end="1995"
                     /protein_start="1986"
                     /score="1.8"
                     /tool="antismash"
                     /translation="GKLDQKALP"
     aSDomain        10104..10301
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE42_RS20690_PCP.2"
                     /evalue="2.40E-21"
                     /label="MOE42_RS20690_PCP.2"
                     /locus_tag="MOE42_RS20690"
                     /protein_end="2079"
                     /protein_start="2013"
                     /score="67.7"
                     /tool="antismash"
                     /translation="EKVMAEIWEELLGLEQLGVSANFFELGGDSIKALQVCARLKQHGF
                     ETTVRELFEHQTLGELSASVR"
     aSDomain        10338..11285
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE42_RS20690_Epimerization.1"
                     /evalue="3.90E-147"
                     /label="MOE42_RS20690_Epimerization.1"
                     /locus_tag="MOE42_RS20690"
                     /protein_end="2407"
                     /protein_start="2091"
                     /score="483.1"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLVIDG"
                     /tool="antismash"
                     /translation="GEMPWTPVQHWLFSQSMTSVHHFNQSVMLYRADRFNSSALREVLK
                     SLVKHHDALRIVCRNIESKPVQVNRGIDLTDEELYFFQQFDIRDDHAKATDHPAGLSSE
                     EKRRIAETADRIQQNIQLETGPLLHAGLFRASDGDHLLLAIHHLVIDGVSWRILFEDFE
                     IGYEQALAGKPIVFPQKTDSFHDYAHQLAAYSDSRGLFREIEYWTEREKQHVERLPRDY
                     TVSSNKLKDTNVIDFELSRQNTEQLLTSVNKAYTTDTNDILLAALGLSLQEWTGYDHLK
                     ISMEGHGRESYLDNIDLSRTVGWFTSIYPVLLDMD"
     CDS_motif       10758..10823
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20690_0021"
                     /evalue="1.80E-11"
                     /label="NRPS-E2"
                     /locus_tag="MOE42_RS20690"
                     /protein_end="2253"
                     /protein_start="2231"
                     /score="36.1"
                     /tool="antismash"
                     /translation="LLLAIHHLVIDGVSWRILFEDF"
     CDS_motif       11226..11276
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20690_0022"
                     /evalue="3.60E-09"
                     /label="NRPS-E5"
                     /locus_tag="MOE42_RS20690"
                     /protein_end="2404"
                     /protein_start="2387"
                     /score="28.5"
                     /tool="antismash"
                     /translation="DLSRTVGWFTSIYPVLL"
     aSDomain        11316..11774
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE42_RS20690_TIGR01720.1"
                     /evalue="7.30E-50"
                     /label="MOE42_RS20690_TIGR01720.1"
                     /locus_tag="MOE42_RS20690"
                     /protein_end="2570"
                     /protein_start="2417"
                     /score="160.8"
                     /tool="antismash"
                     /translation="LGYHIKRTKDMMRRIPHKGVGYGVLKYVSGIWNETGNISNSPEIS
                     FNYLGQFDQDIQMNSFEVSPVQTGDEISPDWERPYILDISGAVSSGCLKMHIVYNRYQY
                     EAQTIQTFAGHFKRILEDIIRHCAAKENREWSAADFSDEELTLEDLSEI"
     CDS_motif       11337..11396
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20690_0023"
                     /evalue="5.70E-09"
                     /label="NRPS-E6"
                     /locus_tag="MOE42_RS20690"
                     /protein_end="2444"
                     /protein_start="2424"
                     /score="28.2"
                     /tool="antismash"
                     /translation="TKDMMRRIPHKGVGYGVLKY"
     aSDomain        11817..11906
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE42_RS20695_NRPS-COM_Nterm.1"
                     /evalue="4.00E-16"
                     /label="MOE42_RS20695_NRPS-COM_Nterm.1"
                     /locus_tag="MOE42_RS20695"
                     /protein_end="30"
                     /protein_start="0"
                     /score="49.9"
                     /tool="antismash"
                     /translation="MSQQSEIQDIYPLSFMQEGMLFHSLFDEQS"
     gene            11817..>13811
                     /locus_tag="MOE42_RS20695"
                     /old_locus_tag="MOE42_20640"
     CDS             11817..>13811
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (0-30). E-value: 4e-16.
                     Score: 49.9. Matches aSDomain:
                     nrpspksdomains_MOE42_RS20695_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (7-304). E-value:
                     3.2e-117. Score: 382.9. Matches aSDomain:
                     nrpspksdomains_MOE42_RS20695_Condensation_DCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010330629.1"
                     /locus_tag="MOE42_RS20695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE42_20640"
                     /product="condensation domain-containing protein"
                     /protein_id="WP_268487135.1"
                     /sec_met_domain="Condensation (E-value: 9.9e-91, bitscore:
                     291.5, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.4e-49, bitscore:
                     155.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQQSEIQDIYPLSFMQEGMLFHSLFDEQSRAYFEQASFTINGRL
                     DLERFQKSMDAIVGRYDIFRTTFIHKNVAKPRQVVLKSRPCRVQFEDISHLDKPDEEKY
                     IETFRQQDKSKGFDLQTDVLMRVSILKSAPERYVCIWSHHHILMDGWCLGIVIKDFLHM
                     YQALGEGRHPYLPPVQPYGKYIKWLMRQDREEAAKYWKERLQDIEKTSSLPRKSVQTSE
                     GKLQQAVFTISEQQTAGLQQIAAASGATLSTVFQALWGLMLQRFNNSDDSVFGSVISGR
                     PTELADVEGMVGLFINTVPVRIQSGALSFSDLVRHMQKELLKAEAYSYFPLYDIQAQSA
                     LKQELIDHIIVFENVPTQQEIEGLNQTGAFDFSVEDFSMAEETNYGCSIKVIPGSSLYV
                     RINFHTDLYDTSMMEEIEGYMQQMIASVIADPDIRASQIPLLNESKTRQIVSEFNKTEA
                     VSPIAPTLHGLFTRQAALTPDRPAIYFANGSLTYGELDAYSNRLAVRLAAKGVTKESIV
                     GILAERSPEMMIAVLAVLKAGGAYLPLDPAYPAGRLSYMLKDSGASLMLTQSGLTVPDF
                     SGETLEVDMAALVDGNPSEVPAGTADSGSLAYLIYTSGSTGQPKGVAVEHRQAVSFLTG
                     MQRQFPLHKEDVIVLKTSFSFDASVWQLFW"
     aSDomain        11838..12728
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE42_RS20695_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="3.20E-117"
                     /label="MOE42_RS20695_Condensation_DCL.1"
                     /locus_tag="MOE42_RS20695"
                     /protein_end="304"
                     /protein_start="7"
                     /score="382.9"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHILMDG"
                     /tool="antismash"
                     /translation="QDIYPLSFMQEGMLFHSLFDEQSRAYFEQASFTINGRLDLERFQK
                     SMDAIVGRYDIFRTTFIHKNVAKPRQVVLKSRPCRVQFEDISHLDKPDEEKYIETFRQQ
                     DKSKGFDLQTDVLMRVSILKSAPERYVCIWSHHHILMDGWCLGIVIKDFLHMYQALGEG
                     RHPYLPPVQPYGKYIKWLMRQDREEAAKYWKERLQDIEKTSSLPRKSVQTSEGKLQQAV
                     FTISEQQTAGLQQIAAASGATLSTVFQALWGLMLQRFNNSDDSVFGSVISGRPTELADV
                     EGMVGLFINTVPVRIQ"
     CDS_motif       11847..11888
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20695_0001"
                     /evalue="3.60E-05"
                     /label="C1_DCL_004-017"
                     /locus_tag="MOE42_RS20695"
                     /protein_end="24"
                     /protein_start="10"
                     /score="15.6"
                     /tool="antismash"
                     /translation="YPLSFMQEGMLFHS"
     CDS_motif       11910..12026
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20695_0002"
                     /evalue="3.00E-17"
                     /label="C2_DCL_024-062"
                     /locus_tag="MOE42_RS20695"
                     /protein_end="70"
                     /protein_start="31"
                     /score="54.9"
                     /tool="antismash"
                     /translation="AYFEQASFTINGRLDLERFQKSMDAIVGRYDIFRTTFIH"
     CDS_motif       12243..12308
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20695_0003"
                     /evalue="8.80E-11"
                     /label="C3_DCL_135-156"
                     /locus_tag="MOE42_RS20695"
                     /protein_end="164"
                     /protein_start="142"
                     /score="34.2"
                     /tool="antismash"
                     /translation="HHHILMDGWCLGIVIKDFLHMY"
     CDS_motif       12354..12392
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20695_0004"
                     /evalue="3.20E-03"
                     /label="C4_DCL_171-183"
                     /locus_tag="MOE42_RS20695"
                     /protein_end="192"
                     /protein_start="179"
                     /score="10.2"
                     /tool="antismash"
                     /translation="PYGKYIKWLMRQD"
     CDS_motif       12627..12722
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20695_0005"
                     /evalue="4.20E-19"
                     /label="C5_DCL_263-294"
                     /locus_tag="MOE42_RS20695"
                     /protein_end="302"
                     /protein_start="270"
                     /score="60.9"
                     /tool="antismash"
                     /translation="DSVFGSVISGRPTELADVEGMVGLFINTVPVR"
     CDS_motif       12768..12884
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20695_0006"
                     /evalue="5.70E-19"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="MOE42_RS20695"
                     /protein_end="356"
                     /protein_start="317"
                     /score="60.6"
                     /tool="antismash"
                     /translation="QKELLKAEAYSYFPLYDIQAQSALKQELIDHIIVFENVP"
     CDS_motif       13410..13451
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20695_0007"
                     /evalue="3.80E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="MOE42_RS20695"
                     /protein_end="545"
                     /protein_start="531"
                     /score="19.9"
                     /tool="antismash"
                     /translation="LAVLKAGGAYLPLD"
     CDS_motif       13635..13694
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE42_RS20695_0008"
                     /evalue="7.20E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="MOE42_RS20695"
                     /protein_end="626"
                     /protein_start="606"
                     /score="33.8"
                     /tool="antismash"
                     /translation="AYLIYTSGSTGQPKGVAVEH"
ORIGIN
        1 ttcaaaaaag gcgacacata tgagaagcag gaatcttatt ggctgaagca gctcggcggc
       61 gagctgcctg tgcttgaact gccggcggac aagccccgtc cggcggtgcg aagcttcgcc
      121 ggtgacaaga tctcatttac tctggaccaa gaagtcacgt ccggcctgaa ccgcctcgcg
      181 cgggaaaacg gaagcaccct gtatatggtg cttcttgcgg cctactcagc tctattggcc
      241 cgtctcagcg ggcaagagga gattgtggtc ggatcgccga tcgccggccg tccacatgaa
      301 gaccttgaac ccgtgctcgg catgtttgtg aacacgttgg cgcttcggac acgcccggag
      361 ggcggaaagg gtttcacaga ctatttgcag gaagtccgtc agacagcgct ggaagcttat
      421 gaacaacagg attatccgtt tgaagaactt gtcgaaaagc taggcgttca gagagacatg
      481 agccgcaatc cgctgtttga tgcgatgttt attcttcaaa acatggaaca acacgacata
      541 catctgccag aaatagaagt cagacgcaac agcttgattc attcgatctc cgtgtttgat
      601 ctgactttgt cggccgtaga atcaggcggg caaatagaat gtgaaatgga attcagcaca
      661 gatgttttct taaaagacac ggtggaacgg tggagctctc atttgatcga acttctgagg
      721 tctgtgacga ctcgtcccga tacagtcctc gcacggcttg agatattgga acaacaagaa
      781 aaacggatga ttgcagaggg gttcaatgac acacaaattg aattttccca aagtgcagat
      841 ttgtttcatc atatattcga agctaagaca gaggaaacac cgcatcacat cgctattatc
      901 gagggagaaa aacaaataac ctatcgtcag cttaatgaac gggcaaatcg tctggccaga
      961 acgctgagaa gaaagggaac gggcccaaat tacacggttg ctattttggc aaatcgatca
     1021 attgatgcag tggtcagtat tctggcggtt ctgaaatctg gcggcaccta tattccgatt
     1081 gatacgcatt accccgaagg aagaatcagg catcttcttc aggatagcgg ggcactcacg
     1141 cttctcgttc agcaggacct caaacacctg attgcagatt tgaccggtat tggcgtttca
     1201 caaatttttt atctagacga tgagtatctg tacgattcgg atgcgtccaa tctgattcca
     1261 gcggctgggc cggaagatgc agcatatatc atatacacgt ccgggacaac aggaacccca
     1321 aaaggagttg tcataaagaa tcgaagtttt actcatgccg ctcttgcttg gcgtgagatc
     1381 taccaattgg agcgtttccc tgttaggctg cttcaaatgg cgagcttttc atttgatgtc
     1441 ttctcgggtg acttggcacg gactttatta aacgggggca ctctagtgat ttgtccggat
     1501 gaagtccggc tggagcctgc tgagctgtac gcattattga ttcagcagcg tattacatta
     1561 atggagtcaa caccggctct catggttcct tttatggatt atgtatatcg cagcaatctt
     1621 tcgctgccag atttacgctt gcttgttctt ggttcagata ctatcaaagc tcaagacttc
     1681 aaaacgctct cacagcgttt tggcaaacag atgcgtttga ttaatagcta tggcgtgaca
     1741 gaagccacca ttgattccag ttactatgaa gctaatatgg gtgccgctgt gaacgaagaa
     1801 tatgtaccaa tcggcgtacc gctgccaaat gtccacatgt acgtactcag caattacgat
     1861 caaatacagc cgatcggtgt tgccggagaa ctttgtatcg gcggagccgg cgtggcgaaa
     1921 gggtatcacg gtaaacctga attgacggaa gccaaattca ctgaacatcc atttatatct
     1981 gatgaaaaga tatacagaac aggagatcaa gcatgctggc ttcctgatgg cactgtgcgt
     2041 ttcctcggcc gtatggacaa ccaggtgaaa atcaagggct acagaattga agcgggagaa
     2101 attgaaagtg tactgcttca gacgggcatg gtcaaagagg ctgcagcggc agtccaaaag
     2161 gatacccagg ggcagtctta tctagcggca tatatagtgc cttcggatgt tgatacgtca
     2221 gctctccgtg acgctctggc gaaggaatta cctgcatata tggttccatc tcatttcatg
     2281 gctctggata aaataccgct gacgcctaac ggcaaagtgg acagaaaggc attgcctgtt
     2341 ccgaacgaag gcttgcgaca gacttatacc gctccataca ccgacaaaca aacaatgatg
     2401 gccggcattt gggaggacgt gcttagtatt tcgcgcgtcg gcatccatga ttcctttttc
     2461 gatcttggcg gagattccat taaggcgctg caagtatcag ccaggcttgc tgcagaaggc
     2521 tggaagatga cgattagaga cttatttcaa tttccaacca ttcagaagct gacagatcat
     2581 attataccgg ccgtttctgc agccgatcag ggacctgttg aaggaaaagc tgttctcacg
     2641 ccaatacagc ggagattttt cagtcagccg gatgcttttc ggtaccatta caaccagtca
     2701 gtcgtgctat tcaatgagat aggatttaga gacgacgctc tccgtcaagc gcttcgccgc
     2761 ttggcagtgc atcacgatgt gcttcgcatg gtttttacaa aagatcaggc agggcgtatc
     2821 attcagcata accgcgggac tggccttcag gatgaggaac tgtatcatct tcatatcaca
     2881 gattggacta aagaaccgca agctcttatc catgcagaag aacaaattgc aaaagaagaa
     2941 gcccgtattc aaaaagcgat gcggcttgaa caagggcctt tgctccaagc gggattgttc
     3001 aaaacagcgg atggtgatta ccttcttatc gctatccatc atcttgttgt ggatggcgtc
     3061 tcttggcgga ttttgctaga ggacctttca gcagcttatc agcatgtgct cgaaggaaga
     3121 gagatcaaat tgcctcctaa aagtgattcg tatctctcat acgcaaacgc tcttgtgcaa
     3181 tcagcggaaa gcagaaaatt attgcaggaa aagccttatt gggaaagtgt tataaatgca
     3241 caaacggctg ttttgcccaa agaccagcct tatgcttctg aaggactgca aaaaaatgcc
     3301 ggcacagcat cattgatact ttcaggcgat tggaccagta agctgctatt tgaaactcag
     3361 caagcctatg gcacagatgt aaatgaactg ttactgactg gattgggcat ggcgttggcc
     3421 gagtggacag gaaacgaaca aattgtaatc agcactgaag gacacggcag ggaaggacac
     3481 gtttccgata ttgatatttc acgaacggtg ggctggttta cttctgtcta tcctgtcctt
     3541 cttaacatgg acgcaaatca ttcagacgat aagctcgcca gccgaatcaa agcgacaaag
     3601 gacatgctga gaagagtgcc gaatcaagga accggctatg ggctattaga atacatgaca
     3661 gaaaatgaag actggaatag agaaccagag gtcagtttca attatctcgg acagtttaac
     3721 gatatagagg attcaaagac gcttcgaatg tcctcttacc agccgcgtta tgaaatagcc
     3781 ggtgagcggt acagagagta tgcgttggac atcaatgcca tgataatcgg cggacagcta
     3841 caagtgaaag cagtgtacac tcaggtgttt catcatagaa ccatcgaact cttcatggag
     3901 agctttcgaa agcatatcat ctgtgccatt gaacattgtt cgggaaaaaa ggaacgtgaa
     3961 aaaacgctga gcgatttcag caacaaagaa atgacatcag cagcactatc aagcatcgca
     4021 aatcttgtaa aagatcttta actttgaaaa aaggtgtgtg tgagatgacg caagctacag
     4081 ggattcaaga catttaccct ttatcgtata tgcaggaagg tatgctgttt cattcattgc
     4141 ttcatggtga ctcgaaagct tatgtggagc agacatcgtt caccattaac ggaaatctat
     4201 gtataaactc atttcaaaaa agcttgaatc tgctggtttc tcggtatgat attttcagaa
     4261 cgatttttat taaggaggtt cctgacctct ccggtccgca gcaagttgtt ctgacaagtc
     4321 gtgaactgac tgtgaaaaaa gaagacattt ctggcatgaa gataaaagaa cagcacattt
     4381 tcattgaaga atataaaaag aaggacagag aaaaaggatt tgatttgcaa aaagacccgc
     4441 tcatgcggct tactcttttt gatatgggtg aaaaccgaca tacttgtgta tggacacatc
     4501 accatatcat catggacggc tggtgtctgg gcattgttct gaaggaattc tttcatatct
     4561 attattctct gaaaaacagc gacccgctgc agcttggcag tacggttccc tacagcagat
     4621 atattggatg gctcggcgaa caggacaagg aagaaacggg tgtgtattgg gacggctacc
     4681 tgagtgatta cggccagaca gcttccattc cgcttacgaa caacaggcgt aaggacggtg
     4741 tgtatgtatc ggaacagatt catttctctc ttgatccatc ttccgttgaa aaactcacag
     4801 ccttatcccg gagcttggga gtgactttaa acaccctatt tatgagtata tggggagtca
     4861 tgctgcatag atacaacgca acggatgatg ccgtgttcgg ctctgtcatt tccggccgcc
     4921 cttcaacgat tgacggaata gaatcaatgg tcggtctgtt tattaacacc attcccgttc
     4981 gggtgcgcgc gcacggaggg atgtcatttt cttctcttgt caaagaagtg caaaaggaca
     5041 cattagcatc tgaaaaccat ggttattatc ctctctatga gattcagaat cgaagccctc
     5101 taaagcaggg cttactcaat cacattcttg tgtttgagaa ttaccctgtc cagatacaaa
     5161 aggcagtcgg cacttggcag gaccaagaag aaaacgcatt gaagcttggg gatttttcaa
     5221 tgtcagaaga aaccaattat gacctaaatg tcgtgattgt gcctggagat aacttttata
     5281 taaaattcag ctacaatgct tccgtgtata agcaggaaga tatgcttcga attcagggcc
     5341 acttgaaaaa agcgctggat tgcattctgt ctgatccgga tattgcagtc gagaacattg
     5401 atattgtacc tgtcgaggaa caaatgctca ttcatacatt taacaagacg gacagacctt
     5461 atccggaaaa aacggtttac gaattatttg aagaccaggc cgccgagact cctgaagcga
     5521 cagctcttgt gctggatgat acgcactgga catatcgcca attagacgaa agggcgaacc
     5581 agatggcgcg tgtgcttaag gaaaagggag caaaacctgg cagcatcgtg gccgtcatga
     5641 tgcgacggtc aaaggaaatg gcagcggctc tgctcgggat ttggaaagcg ggcagtgcat
     5701 atatgcctct tgatcccggc tatccgtctg aacggctgtc ttttctgtta gatgacagcg
     5761 aaacatcttt gctgctgaca gaggatgaac tcatttcgac tgtgccttcg gattatgccg
     5821 gagacactgt gacaacagag gaagccttgt catataaaac cgatccgctt ccaacgacaa
     5881 tacaagccgg aaagctggcc tatctcatct acacttcagg aacgaccggg cggcctaaag
     5941 gagttcttgt ggaccaccgt ggaattgcaa atacattgca atggagacgg gaagagtacg
     6001 gcatgagcgg tcaagatacc gcgctgcacc tgttttcata tgtctttgac ggctgcgtga
     6061 cgagcttgtt cactccgctt ttatcaggtg cctgtgtgat tttgacaaat gacgatgatg
     6121 cgaaagatgt acttgcaatt aagaaaacca tagccaaaca tcgggtcact catctgctga
     6181 ttgtgccttc actgcatcgg gttttgctgg aagttttaga aaaagaagaa gccaagaccc
     6241 ttcgcgttgt gacatttgcg ggagagccgg tcaccgcaga tttacttgaa gccagccggg
     6301 aaatttgtcc gcacacagaa ttagcaaacg aatacgggcc gacagaaaat agtgttgcga
     6361 cgaccgtgct tcgtcatctg aatcaggaat catgtattac gatcgggcgt ccgattgcca
     6421 ataccgaagt gtgtatttta atcggtaacc aattgcagcc gataggcgca ttgggtgaac
     6481 tttgtatcgg aggcgcaggt ttggcgcaag gctactataa acagactgaa ttgtcgcaaa
     6541 aagcatttac atcacatccg tttcgagaag gagaacgcct ataccggacg ggagatgcgg
     6601 cgcgctggct gcaggacgga acgttagaat atatcggccg ttttgatgac caagtgaaaa
     6661 ttagaggcta ccggattgaa ttgggagaag tagaagcagt tctccgaaac ataccgggag
     6721 taaaagaagc ggcggtcgta gcccgtgaaa cctcttcaga cgaacgggag ctttttgctt
     6781 atatcgttcc gcaaaaggga gaagggcttc cagacgtaca tcttcatctt gctgggaaat
     6841 taccggctta tatgattccg gcgagtatta caaaaataaa caagatgccg ttaacttcaa
     6901 gcggaaaact ggaccgctca gctctgccgg aaccgatgaa catggcggac tcagctcata
     6961 cgtatgaacc gcctcgcacg attattgaat ctgaattaac cgcgatttgg aaaaacgtgc
     7021 tgaataagaa gcagatcggc atacgcgatg atttcttcca cttaggcggg cagtcattaa
     7081 aagccgctac acttgtatca agaatacata aaaagctgaa tatccagctg ccgctcagcg
     7141 aagtgtttat atatccgaca gtagaaagca tggcagctaa aatcgaaagc ttaaaagaac
     7201 aaacatttac aacaattgct ccagcgcaat caagagaact gtacccgctg tctttttcac
     7261 agaaaaggat gtataccctt catcaactgg aggagaacgg tacaggatac aatatgccgg
     7321 cagcgctgga actgcacgga aagctcgatc gccagcggct gaaacaggct gtcacagaac
     7381 ttgtgaaccg gcatgaatca ctccgcactt cgtttgtcat acacaatggt gaaccgatgc
     7441 agcaagtcca tgtaagcctg acaccggagt ttaccgagct tcagattgaa tcaaaaagcc
     7501 agctgaaaca gacgatgcag tcatttatac agccgtttgt tttgacaaac gcaccgttgc
     7561 ttagagcatg cttaatcgtt ttagaaaatg atcatcatta tctgttgctg gatatgcatc
     7621 acattgctgc tgacggtgtc tctatgagca cacttatcca agaattcaca gacctgtact
     7681 gcggcaagac gcttcatcca ttaaagctgc agtacaagga ttttgcagtc tggcaaaaag
     7741 agcagtttgc ccggcagtta ttcagcaaac aggaagatta ctggctgaaa cagctcagcg
     7801 gcctgcctgt attagaactg ccgcttgata aaaaccgtcc gcttctgcct gatttcagcg
     7861 gcgggacatt tgaagcagaa attgatcgcg agactgcaga acggctacat cgtatcatgt
     7921 ctgaaacggg ctgtacgttg tatatggttc ttcttgctgc ctattcgatt ctgctttcta
     7981 agctaagcgg acaaaaggat attgttgtcg gttcacctgc tgccggaaga cggcatgccg
     8041 atttggagcc ggtcatcgga ctgtttgtga atacccttgc gatgcggagc cagcctgaag
     8101 gagaaaagtc tttcagatct tatttgcaag aaattaaaga agtggccctt accgcatatg
     8161 aacatcagga ttttcctttt gagaagctca caaacaaact cggaactcag agagaattga
     8221 atcgcaatcc gcttttcgat gcaatgctgg tgcttcaaag cagtgaagat tttcagcttg
     8281 aattgcccgg actggcaata tcttctcgca agctgccgca tgaggcgtct aaattcgatc
     8341 tgaccttgca cgctgaggaa aacaaggaag gaattcgctg ctgctttgag tacagcaccg
     8401 cattatttga gcacgaaacc gttgcgcgct gggccaatca tttcaaggaa ctgctgagaa
     8461 gtataacggc cgatacagac gtgaagctgg ctgatatgca gatgcttgga ggctcagagc
     8521 aacgtatgct gctggacaat atgcatcatt tatctgacta tccgagaaat aaaagtctcc
     8581 cggatttatt tgaaaattgg gcaaaagaaa caccggagca tatagcagtg gtgatggacg
     8641 atcaccggct gacttaccgc gagctgaatg atcaagcaga acgggcagca gctatgctga
     8701 tgaaaaaggg agtacgctct gaacaaattg tcggtttgat gacagaacgc tcacccgata
     8761 tgctgatcgg aattcttgcc attctaaaag cgggcggagc ctacctgccg attgatcccg
     8821 attatcctca ggaacgtatc aatttcatgc ttcatgacag cggagcggag atgttgctga
     8881 cccatactgc gaaagagaga cctgatggtt atcaagggga aattttgtat atagaagatg
     8941 ctgagaacga accaccgagt gatgtgcaaa aaccgtctgt ccgcgcagaa cagcctgcat
     9001 atatcatcta cacatcaggt acgaccggcc agccaaaggg agttgcagtc gagcatcgca
     9061 atgtagtcag cttattgaaa cataaagaac tgccttttga ttttggtcct caggatgtgt
     9121 ggacattgtt ccattcatat tgctttgatt tttctgtgtg ggaaatgttt ggcgcactct
     9181 taaacggcgg cacattagtt gtggtttcaa aagaaatagc ccgggacccg aatgcttatc
     9241 ggctgctgct gaaagaagaa ggggtaaccg tactgaatca gacgccgacg gctttttaca
     9301 gtctcatgca tgaagaacaa tctcatgccg atgcattaag cgtccgttac gtcattttcg
     9361 ggggggaggc attacagccc ggaatgctgc gcagctggaa aggcaaatat ccggagacag
     9421 acctgattaa tatgtacggc attacagaaa cgactgtcca tgtgacgtat aaaaagctgg
     9481 ccgatataga tatcgcagcg aataaaagca atatcgggaa accgctcgca acccttacag
     9541 catatgtatt ggacgattat atgaattttc agcctatagg gatccccggc gagctgtatg
     9601 ttggcggcgc tggagtagcg aagggatatg taaacaggga agagctgact gcagcaagat
     9661 ttattccgaa tccctatgtg cctggcgaca ggctgtaccg cacgggagac atcgccaagc
     9721 ggctgccgaa tggcgagctt gaatatgagg gacggataga taaccaggtg aaagtcagag
     9781 ggcaccgtat agaactcggt gaaatcaaag cggctcttct caaacattca ctgattaaag
     9841 aagcggctgt aattacaagg cttgatgaac aaggacagca taccatttat gcttatctga
     9901 tctcagagac agatcgcaaa ctgaatcaat caaaaatccg cgcctccctg aaagccgttt
     9961 tgccagatta tatgataccg gcccgattca tgcagcttga cagcatgccg cttacgagta
    10021 acggaaagct tgatcagaag gcgctccctg aaccagatgc gggcacccgt atatctgatg
    10081 atattttgcc gagaaatgac actgaaaagg tgatggctga gatttgggag gaactgctgg
    10141 ggcttgagca gcttggtgtc agcgcgaatt tctttgaact tggcggagat tcaattaaag
    10201 cgctgcaagt ctgtgcaagg ctgaagcagc acgggtttga aacaacagtg cgggaactgt
    10261 ttgagcatca gacattgggc gagctgtccg caagtgtccg taaaattgaa cgtgtgatcg
    10321 accaagcgcc tgttagcggt gaaatgcctt ggacacctgt acagcattgg cttttttccc
    10381 agtcaatgac gtcagttcac cattttaatc agtccgtcat gctgtatcga gctgaccgat
    10441 ttaacagcag cgctctcaga gaagttctga aaagtttggt aaagcaccat gacgcattac
    10501 gaatcgtctg ccggaatata gagagcaagc cggtgcaggt taaccgaggc attgatctca
    10561 ctgatgaaga attatatttc tttcaacagt ttgatataag agatgatcat gcaaaagcaa
    10621 ctgatcatcc ggccggtttg tcaagtgagg aaaagagacg gattgcagag acggcagatc
    10681 gtatccagca aaacattcaa ttggaaacag gtcctctgct tcatgccggc ttgttccgtg
    10741 cttcagacgg agaccatttg ctgctcgcta ttcatcatct cgttatcgac ggtgtatctt
    10801 ggcgaatttt gtttgaagat ttcgagattg gctatgaaca agcactggca ggaaaaccaa
    10861 tcgtattccc gcaaaaaacg gattcttttc atgattatgc ccatcaattg gctgcatact
    10921 ctgactcacg cgggcttttc cgtgaaatag agtactggac agagcgtgaa aaacagcatg
    10981 ttgaacgcct tcctagagat tacaccgtgt catctaataa gctcaaagat accaatgtaa
    11041 ttgatttcga gctttccaga cagaacacag agcagctgtt aacatccgtc aacaaggctt
    11101 acaccactga caccaatgat atcctgcttg ccgctttagg gctttcctta caggaatgga
    11161 caggctatga tcatctgaaa atcagcatgg aaggacacgg cagggaatca taccttgata
    11221 acattgatct aagccgaaca gtcgggtggt tcacttcgat ttatccggtt ttgcttgaca
    11281 tggatgtttc tgaacatacc gatgaaaaag agcggcttgg ctaccatatt aaacgtacga
    11341 aagacatgat gcgccgcatc cctcataaag gcgtcggcta cggagttcta aaatacgtaa
    11401 gcggtatttg gaatgagaca gggaatattt caaacagccc tgaaatcagt tttaactatt
    11461 taggccagtt tgatcaagat atacaaatga attcgtttga agtttctccg gttcaaacag
    11521 gagacgagat aagcccggat tgggagcgcc cttatattct tgatattagc ggcgccgttt
    11581 cgtcaggatg tctgaaaatg cacattgtct ataaccgcta tcaatatgag gcgcagacga
    11641 tccaaacatt cgccggacat tttaaacgta ttctcgaaga catcatacgg cactgtgcgg
    11701 ctaaagaaaa ccgcgaatgg agtgccgctg atttcagtga tgaggagtta acgctagaag
    11761 acctcagtga aattatggga gccgtcaaca aactatagaa aaaggagagg cgctacatgt
    11821 cgcaacaatc cgaaattcag gatatttatc ccctgtcatt tatgcaggag ggcatgcttt
    11881 ttcattcgct gtttgatgaa caatcaagag cctattttga acaggcatcc tttaccatca
    11941 acggaaggct agacttggaa cgcttccaaa aaagtatgga tgccattgtt ggccgatatg
    12001 acatctttcg tacaactttc attcacaaaa atgtagccaa gcctaggcaa gtcgtgctca
    12061 aaagccgtcc atgccgcgtt cagtttgagg atatttccca tcttgataag ccagatgaag
    12121 agaaatatat cgaaaccttt cggcaacaag ataagtccaa aggctttgat ctgcaaacag
    12181 atgtccttat gagggtatcc attttgaaat cggcacctga gcgctatgtc tgtatttgga
    12241 gccatcacca tattttgatg gacggatggt gcctcggcat tgtcattaaa gattttctcc
    12301 acatgtatca ggccctgggc gaagggcgtc atccttacct tcctccggtt cagccgtacg
    12361 gaaaatatat caagtggctg atgcggcaag accgcgaaga ggcggcaaag tattggaaag
    12421 agcggcttca agatattgaa aagacatcat ccctgccaag aaaaagtgtt caaacatcag
    12481 aaggaaaatt acagcaggct gtatttacaa tctcggaaca gcaaactgcc ggattacagc
    12541 aaattgcagc agcttccggg gcgacgctga gcacggtttt tcaagcgttg tggggactga
    12601 tgctgcaacg attcaataac agtgacgatt ctgtgttcgg ttctgtaatt tccggcagac
    12661 caacggagct tgcagacgtg gagggcatgg tcgggctctt tatcaataca gttcccgttc
    12721 gcatccaaag cggagcgctt tccttctcgg atctggtcag gcatatgcaa aaggagttac
    12781 tgaaagcaga agcttatagt tattttcctt tgtatgatat tcaagcgcaa agcgcactca
    12841 agcaggaact gatcgatcat attatcgtat ttgaaaatgt gccgacacag caggaaattg
    12901 agggattgaa ccagaccggg gcgtttgatt tttcggtgga ggacttttcg atggctgagg
    12961 aaaccaacta cgggtgcagt ataaaagtca ttccgggatc ctctttatat gtacggatca
    13021 attttcatac agatttgtat gacaccagca tgatggaaga gatcgaaggg tatatgcagc
    13081 aaatgattgc atctgttatc gctgaccctg atatacgcgc ttcacagatt ccattgctaa
    13141 atgaaagcaa aacacggcaa attgtttctg aattcaacaa aacagaagct gtttcgccta
    13201 tagctccgac tctccacggc ctgtttacac gccaggcggc gcttacgccg gatcggccgg
    13261 cgatttactt cgctaatggg agtctgacat acggggagct tgatgcgtat tcaaacaggc
    13321 tggccgtacg ccttgcggcg aaaggcgtga cgaaagaaag catcgtcggc atccttgccg
    13381 agcgctcgcc ggaaatgatg attgccgtgc tggccgtttt gaaagcgggc ggcgcttatc
    13441 tgccgcttga tccggcgtat cctgccgggc gcctgagcta catgctgaaa gacagcgggg
    13501 cttctcttat gctgacacag tctggtttaa cggttcccga tttttcaggt gagacgcttg
    13561 aagtggatat ggcggcgctt gtggatggca atccttcaga agtgcctgca ggcacagccg
    13621 acagcggctc tctggcgtat ctcatttata cctccggctc cacggggcag ccaaagggcg
    13681 tggcggtgga gcatcgccag gcggtttctt ttctgaccgg catgcaacgg cagtttccgt
    13741 tacataaaga ggatgtcatt gtgctgaaaa cgtcattttc atttgacgcg tctgtctggc
    13801 agctgttctg g
//
