LOCUS       NZ_JALAUJ010000014     14982 bp    DNA     linear   CON 26-JAN-2024
DEFINITION  Bacillus atrophaeus strain CK4F1-4 Contig_0000014, whole genome
            shotgun sequence.
ACCESSION   NZ_JALAUJ010000014
VERSION     NZ_JALAUJ010000014.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus atrophaeus
  ORGANISM  Bacillus atrophaeus
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 14982)
  AUTHORS   Dunlap,C.
  TITLE     Crop Bioprotection Bacillus Genome Sequencing
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 14982)
  AUTHORS   Dunlap,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-FEB-2022) CBP, USDA-ARS-NCAUR, 1815 N. University St.,
            Peoria, IL 61604, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC NGS Cell v. 21
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 412.8916062413295x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/24/2024 02:32:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,185
            CDSs (total)                      :: 4,107
            Genes (coding)                    :: 3,961
            CDSs (with protein)               :: 3,961
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 68
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 83 of 146
            Pseudo Genes (incomplete)         :: 103 of 146
            Pseudo Genes (internal stop)      :: 25 of 146
            Pseudo Genes (multiple problems)  :: 59 of 146
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:43:01
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 14982
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JALAUJ010000014.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..14982
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     gene            <1..5169
                     /locus_tag="MOE37_RS20845"
                     /old_locus_tag="MOE37_20790"
     CDS             <1..5169
                     /NRPS_PKS="Domain: PCP (132-200). E-value: 1.5e-24. Score:
                     77.9. Matches aSDomain: nrpspksdomains_MOE37_RS20845_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (215-495). E-value:
                     6.9e-106. Score: 345.5. Matches aSDomain:
                     nrpspksdomains_MOE37_RS20845_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (661-1068). E-value: 8e-101.
                     Score: 329.5. Matches aSDomain:
                     nrpspksdomains_MOE37_RS20845_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1173-1238). E-value: 4.8e-22.
                     Score: 69.9. Matches aSDomain:
                     nrpspksdomains_MOE37_RS20845_PCP.2"
                     /NRPS_PKS="Domain: Epimerization (1249-1559). E-value:
                     8.7e-147. Score: 482.0. Matches aSDomain:
                     nrpspksdomains_MOE37_RS20845_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (1567-1714). E-value: 3.3e-44.
                     Score: 142.4. Matches aSDomain:
                     nrpspksdomains_MOE37_RS20845_TIGR01720.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019846737.1"
                     /locus_tag="MOE37_RS20845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE37_20790"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_268533741.1"
                     /sec_met_domain="PP-binding (E-value: 6.3e-17, bitscore:
                     49.7, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 1.1e-93, bitscore:
                     301.2, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 4.2e-111, bitscore:
                     359.0, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="RMYKTGDLARWLPDGQVEFLGRLDDQVKIRGYRIEPGEIESALRN
                     LEGVQEAAVITRADSGEAELCAYVQGRDKNDVRAQLALVLPGYMIPAHFVQINTWPITP
                     SGKLDRKALPAPDGAAGQESYKAPRNLTEMKLAQLWEDVLKNGPVGITDDFFDRGGHSL
                     KATALISRIAKAFGVQVPLKDIFARPTVEGLASVIRELEESPYAAIEPAEKRDTYPVSS
                     AQKRMYVLQQLEDGGVGYNMPAVLELEGKLDRKRMEAAFQALISRHESLRTSFETGNGG
                     EPIQRIHHEVPFTVTEENSADAFVRPFVLSQAPLFRAGLVKETNERHVLLVDMHHIISD
                     GVSVNTLIQEFGELYAERKLEPLRIQYKDYAVWQQDFKKGDTYEKQESYWVKQLGGELP
                     VLELPADKPRPAVRSFAGDKISFTLDQEVTSGLNRLARENGSTLYMVLLAAYSALLSRL
                     SGQEEIVVGSPIAGRPHEDLEPVLGMFVNTLALRTRPEGGKGFTDYLQEVRQTALEAYE
                     HQDYPFEELVEKLGVQRDMSRNPLFDAMFILQNMEQHDIHLPEIEVRRNSLIHSISVFD
                     LTLSAVESGGQIECEMEFSTDVFLKDTVERWSSHLIELLRSVTARPDTVLARLEILEEQ
                     EKRMIAEGFNDTQIEFSQSADLFHHIFEAKTEETPHHIAIIEGEKQITYHQLNERANRL
                     ARTLRRKGTGPNYSVAILANRSIDAVVSILAVLKSGGTYIPIDTHYPEGRIRNLLQDSG
                     AVTLLVQQDLKHLIADLTGIGVSQIFYLDDEYLYDSDASNLIPAAGPEDAAYIIYTSGT
                     TGTPKGVVIKNRSFTHAALAWREIYQLERFPVRLLQMASFSFDVFSGDLARTLLNGGTL
                     VICPDEVRLEPAELYALLIQQRITLMESTPALMVPFMDYVYRSNLSLPDLRLLVLGSDT
                     IKAQDFKTLSQRFGKQMRLINSYGVTEATIDSSYYEANMGAAVNEEYVPIGVPLPNVHM
                     YVLSNYDQIQPIGVAGELCIGGAGVAKGYHGKPELTEAKFTEHPFISDEKIYRTGDQAC
                     WLPDGTVRFLGRMDNQVKIKGYRIEAGEIESVLLQTGMVKEAAAAVQKDPQGQSYLAAY
                     IVPSDVDTSALRDALAKELPAYMVPSHFMALDKIPLTPNGKVDRKALPVPNEGLRQAYT
                     APCTDKQTMMAGIWEDVLSISRVGIHDSFFDLGGDSIKALQVSARLAAEGWKMTIRDLF
                     QFPTIQKLTDHITPAVSAADQGPVEGKAVLTPIQRRFFSQPDAFRYHYNQSVMLFNEIG
                     FRDDALRQALRRLAVHHDALRMVFTKDQAGLIIQHNRGTDLQDEELYHLHITDWTKEPQ
                     ALIHAEEQIAKEEARIQKAMRLEQGPLLQAGLFKTADGDYLLIAIHHLVVDGVSWRILL
                     EDLSAAYQHALEGREIKLPPKSDSYLSYANALVQSAENRKLLQEKPYWESVINAQTAVL
                     PKDQPYASEGLQKNAGTASLILSGDWTSKLLFETQQAYGTDVNELLLTGLGMALAEWTG
                     NEQIVISTEGHGREGHVSDIDISRTVGWFTSVYPVLLNMDANHSDDKLASRIKATKDML
                     RRVPNQGTGYGLLEYMTENEDWNREPEVSFNYLGQFNDIEDSKTLRMSSYQPRYEIAGE
                     RYREYALDINAMIIGGQLQVKAVYTQVFHHRTIELFMESFRKHIISAIEHCSGKKEREK
                     TLSDFSNKEMTSAALSSIANLVKDL"
     source          1..14982
                     /db_xref="taxon:1452"
                     /isolation_source="soil"
                     /mol_type="genomic DNA"
                     /organism="Bacillus atrophaeus"
                     /strain="CK4F1-4"
                     /submitter_seqid="Contig_0000014"
     cand_cluster    1..14982
                     /SMILES="NC(CCCN)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(C(O)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..14982
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<0:>14982](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      <1..>14982
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     CDS_motif       58..123
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20845_0001"
                     /evalue="9.50E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="MOE37_RS20845"
                     /protein_end="40"
                     /protein_start="18"
                     /score="39.9"
                     /tool="antismash"
                     /translation="FLGRLDDQVKIRGYRIEPGEIE"
     CDS_motif       319..345
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20845_0002"
                     /evalue="1.30E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="MOE37_RS20845"
                     /protein_end="114"
                     /protein_start="105"
                     /score="5.4"
                     /tool="antismash"
                     /translation="GKLDRKALP"
     aSDomain        400..603
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE37_RS20845_PCP.1"
                     /evalue="1.50E-24"
                     /label="MOE37_RS20845_PCP.1"
                     /locus_tag="MOE37_RS20845"
                     /protein_end="200"
                     /protein_start="132"
                     /score="77.9"
                     /tool="antismash"
                     /translation="EMKLAQLWEDVLKNGPVGITDDFFDRGGHSLKATALISRIAKAFG
                     VQVPLKDIFARPTVEGLASVIRE"
     aSDomain        649..1488
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE37_RS20845_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="6.90E-106"
                     /label="MOE37_RS20845_Condensation_LCL.1"
                     /locus_tag="MOE37_RS20845"
                     /protein_end="495"
                     /protein_start="215"
                     /score="345.5"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIISDG"
                     /tool="antismash"
                     /translation="DTYPVSSAQKRMYVLQQLEDGGVGYNMPAVLELEGKLDRKRMEAA
                     FQALISRHESLRTSFETGNGGEPIQRIHHEVPFTVTEENSADAFVRPFVLSQAPLFRAG
                     LVKETNERHVLLVDMHHIISDGVSVNTLIQEFGELYAERKLEPLRIQYKDYAVWQQDFK
                     KGDTYEKQESYWVKQLGGELPVLELPADKPRPAVRSFAGDKISFTLDQEVTSGLNRLAR
                     ENGSTLYMVLLAAYSALLSRLSGQEEIVVGSPIAGRPHEDLEPVLGMFVNTLALRTRP"
     aSModule        649..5145
                     /complete
                     /domains="nrpspksdomains_MOE37_RS20845_Condensation_LCL.1"
                     /domains="nrpspksdomains_MOE37_RS20845_AMP-binding.1"
                     /domains="nrpspksdomains_MOE37_RS20845_PCP.2"
                     /domains="nrpspksdomains_MOE37_RS20845_Epimerization.1"
                     /domains="nrpspksdomains_MOE37_RS20845_TIGR01720.1"
                     /locus_tags="MOE37_RS20845"
                     /monomer_pairings="Orn -> D-Orn"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       691..723
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20845_0003"
                     /evalue="1.60E+01"
                     /label="NRPS-E6"
                     /locus_tag="MOE37_RS20845"
                     /protein_end="240"
                     /protein_start="229"
                     /score="-1.4"
                     /tool="antismash"
                     /translation="LQQLEDGGVGY"
     CDS_motif       721..828
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20845_0004"
                     /evalue="1.30E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="MOE37_RS20845"
                     /protein_end="275"
                     /protein_start="239"
                     /score="56.1"
                     /tool="antismash"
                     /translation="YNMPAVLELEGKLDRKRMEAAFQALISRHESLRTSF"
     CDS_motif       1003..1068
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20845_0005"
                     /evalue="7.00E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="MOE37_RS20845"
                     /protein_end="355"
                     /protein_start="333"
                     /score="28.2"
                     /tool="antismash"
                     /translation="MHHIISDGVSVNTLIQEFGELY"
     CDS_motif       1099..1131
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20845_0006"
                     /evalue="1.00E-03"
                     /label="C4_LCL_164-176"
                     /locus_tag="MOE37_RS20845"
                     /protein_end="376"
                     /protein_start="365"
                     /score="11.8"
                     /tool="antismash"
                     /translation="QYKDYAVWQQD"
     CDS_motif       1390..1479
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20845_0007"
                     /evalue="1.30E-15"
                     /label="C5_LCL_267-296"
                     /locus_tag="MOE37_RS20845"
                     /protein_end="492"
                     /protein_start="462"
                     /score="49.6"
                     /tool="antismash"
                     /translation="EIVVGSPIAGRPHEDLEPVLGMFVNTLALR"
     CDS_motif       1528..1647
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20845_0008"
                     /evalue="6.90E-24"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="MOE37_RS20845"
                     /protein_end="548"
                     /protein_start="508"
                     /score="76.4"
                     /tool="antismash"
                     /translation="RQTALEAYEHQDYPFEELVEKLGVQRDMSRNPLFDAMFIL"
     aSDomain        1987..3207
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE37_RS20845_AMP-binding.1"
                     /evalue="8.00E-101"
                     /label="MOE37_RS20845_AMP-binding.1"
                     /locus_tag="MOE37_RS20845"
                     /protein_end="1068"
                     /protein_start="661"
                     /score="329.5"
                     /specificity="substrate consensus: Orn"
                     /tool="antismash"
                     /translation="FEAKTEETPHHIAIIEGEKQITYHQLNERANRLARTLRRKGTGPN
                     YSVAILANRSIDAVVSILAVLKSGGTYIPIDTHYPEGRIRNLLQDSGAVTLLVQQDLKH
                     LIADLTGIGVSQIFYLDDEYLYDSDASNLIPAAGPEDAAYIIYTSGTTGTPKGVVIKNR
                     SFTHAALAWREIYQLERFPVRLLQMASFSFDVFSGDLARTLLNGGTLVICPDEVRLEPA
                     ELYALLIQQRITLMESTPALMVPFMDYVYRSNLSLPDLRLLVLGSDTIKAQDFKTLSQR
                     FGKQMRLINSYGVTEATIDSSYYEANMGAAVNEEYVPIGVPLPNVHMYVLSNYDQIQPI
                     GVAGELCIGGAGVAKGYHGKPELTEAKFTEHPFISDEKIYRTGDQACWLPDGTVRFLGR
                     MDNQVKIK"
     CDS_motif       2173..2214
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20845_0009"
                     /evalue="5.60E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="MOE37_RS20845"
                     /protein_end="737"
                     /protein_start="723"
                     /score="13.4"
                     /tool="antismash"
                     /translation="LAVLKSGGTYIPID"
     CDS_motif       2413..2469
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20845_0010"
                     /evalue="3.30E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="MOE37_RS20845"
                     /protein_end="822"
                     /protein_start="803"
                     /score="28.8"
                     /tool="antismash"
                     /translation="AYIIYTSGTTGTPKGVVIK"
     CDS_motif       3001..3090
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20845_0011"
                     /evalue="8.40E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="MOE37_RS20845"
                     /protein_end="1029"
                     /protein_start="999"
                     /score="50.0"
                     /tool="antismash"
                     /translation="PIGVAGELCIGGAGVAKGYHGKPELTEAKF"
     CDS_motif       3172..3237
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20845_0012"
                     /evalue="1.50E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="MOE37_RS20845"
                     /protein_end="1078"
                     /protein_start="1056"
                     /score="33.1"
                     /tool="antismash"
                     /translation="FLGRMDNQVKIKGYRIEAGEIE"
     CDS_motif       3442..3468
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20845_0013"
                     /evalue="9.70E-02"
                     /label="NRPS-A_a10"
                     /locus_tag="MOE37_RS20845"
                     /protein_end="1155"
                     /protein_start="1146"
                     /score="5.7"
                     /tool="antismash"
                     /translation="GKVDRKALP"
     aSDomain        3523..3717
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE37_RS20845_PCP.2"
                     /evalue="4.80E-22"
                     /label="MOE37_RS20845_PCP.2"
                     /locus_tag="MOE37_RS20845"
                     /protein_end="1238"
                     /protein_start="1173"
                     /score="69.9"
                     /tool="antismash"
                     /translation="TMMAGIWEDVLSISRVGIHDSFFDLGGDSIKALQVSARLAAEGWK
                     MTIRDLFQFPTIQKLTDHIT"
     aSDomain        3751..4680
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE37_RS20845_Epimerization.1"
                     /evalue="8.70E-147"
                     /label="MOE37_RS20845_Epimerization.1"
                     /locus_tag="MOE37_RS20845"
                     /protein_end="1559"
                     /protein_start="1249"
                     /score="482.0"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLVVDG"
                     /tool="antismash"
                     /translation="EGKAVLTPIQRRFFSQPDAFRYHYNQSVMLFNEIGFRDDALRQAL
                     RRLAVHHDALRMVFTKDQAGLIIQHNRGTDLQDEELYHLHITDWTKEPQALIHAEEQIA
                     KEEARIQKAMRLEQGPLLQAGLFKTADGDYLLIAIHHLVVDGVSWRILLEDLSAAYQHA
                     LEGREIKLPPKSDSYLSYANALVQSAENRKLLQEKPYWESVINAQTAVLPKDQPYASEG
                     LQKNAGTASLILSGDWTSKLLFETQQAYGTDVNELLLTGLGMALAEWTGNEQIVISTEG
                     HGREGHVSDIDISRTVGWFTSVYPVLLNM"
     CDS_motif       3766..3792
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20845_0014"
                     /evalue="5.90E-03"
                     /label="NRPS-E1"
                     /locus_tag="MOE37_RS20845"
                     /protein_end="1263"
                     /protein_start="1254"
                     /score="9.9"
                     /tool="antismash"
                     /translation="LTPIQRRFF"
     CDS_motif       3865..3927
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20845_0015"
                     /evalue="4.80E-04"
                     /label="C2_LCL_024-062"
                     /locus_tag="MOE37_RS20845"
                     /protein_end="1308"
                     /protein_start="1287"
                     /score="12.6"
                     /tool="antismash"
                     /translation="DALRQALRRLAVHHDALRMVF"
     CDS_motif       4153..4218
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20845_0016"
                     /evalue="7.90E-12"
                     /label="NRPS-E2"
                     /locus_tag="MOE37_RS20845"
                     /protein_end="1405"
                     /protein_start="1383"
                     /score="37.3"
                     /tool="antismash"
                     /translation="LLIAIHHLVVDGVSWRILLEDL"
     CDS_motif       4624..4674
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20845_0017"
                     /evalue="5.10E-09"
                     /label="NRPS-E5"
                     /locus_tag="MOE37_RS20845"
                     /protein_end="1557"
                     /protein_start="1540"
                     /score="28.1"
                     /tool="antismash"
                     /translation="DISRTVGWFTSVYPVLL"
     aSDomain        4705..5145
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE37_RS20845_TIGR01720.1"
                     /evalue="3.30E-44"
                     /label="MOE37_RS20845_TIGR01720.1"
                     /locus_tag="MOE37_RS20845"
                     /protein_end="1714"
                     /protein_start="1567"
                     /score="142.4"
                     /tool="antismash"
                     /translation="LASRIKATKDMLRRVPNQGTGYGLLEYMTENEDWNREPEVSFNYL
                     GQFNDIEDSKTLRMSSYQPRYEIAGERYREYALDINAMIIGGQLQVKAVYTQVFHHRTI
                     ELFMESFRKHIISAIEHCSGKKEREKTLSDFSNKEMTSAALSS"
     CDS_motif       4726..4788
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20845_0018"
                     /evalue="3.00E-08"
                     /label="NRPS-E6"
                     /locus_tag="MOE37_RS20845"
                     /protein_end="1595"
                     /protein_start="1574"
                     /score="25.9"
                     /tool="antismash"
                     /translation="TKDMLRRVPNQGTGYGLLEYM"
     aSDomain        5193..5282
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE37_RS20850_NRPS-COM_Nterm.1"
                     /evalue="2.70E-16"
                     /label="MOE37_RS20850_NRPS-COM_Nterm.1"
                     /locus_tag="MOE37_RS20850"
                     /protein_end="30"
                     /protein_start="0"
                     /score="50.5"
                     /tool="antismash"
                     /translation="MTQATGIQDIYPLSYMQEGMLFHSLLHGDS"
     gene            5193..12926
                     /locus_tag="MOE37_RS20850"
                     /old_locus_tag="MOE37_20795"
     CDS             5193..12926
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (0-30). E-value: 2.7e-16.
                     Score: 50.5. Matches aSDomain:
                     nrpspksdomains_MOE37_RS20850_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (7-309). E-value:
                     2.7e-108. Score: 353.6. Matches aSDomain:
                     nrpspksdomains_MOE37_RS20850_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (474-867). E-value:
                     6.9e-111. Score: 362.7. Matches aSDomain:
                     nrpspksdomains_MOE37_RS20850_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (974-1042). E-value: 1.3e-22. Score:
                     71.7. Matches aSDomain: nrpspksdomains_MOE37_RS20850_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1058-1344). E-value:
                     3.6e-105. Score: 343.2. Matches aSDomain:
                     nrpspksdomains_MOE37_RS20850_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1508-1905). E-value:
                     1.9e-116. Score: 381.0. Matches aSDomain:
                     nrpspksdomains_MOE37_RS20850_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2013-2079). E-value: 1.2e-21.
                     Score: 68.6. Matches aSDomain:
                     nrpspksdomains_MOE37_RS20850_PCP.2"
                     /NRPS_PKS="Domain: Epimerization (2091-2407). E-value:
                     2.8e-146. Score: 480.3. Matches aSDomain:
                     nrpspksdomains_MOE37_RS20850_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (2417-2570). E-value: 7.3e-50.
                     Score: 160.8. Matches aSDomain:
                     nrpspksdomains_MOE37_RS20850_TIGR01720.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003242403.1"
                     /locus_tag="MOE37_RS20850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE37_20795"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_268533744.1"
                     /sec_met_domain="Condensation (E-value: 2e-90, bitscore:
                     290.6, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.6e-125, bitscore:
                     405.8, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.3e-17, bitscore:
                     51.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQATGIQDIYPLSYMQEGMLFHSLLHGDSKAYVEQTSFTINGNL
                     CIDSFQKSLNLLVSRYDIFRTIFIKEVPDLSGPQQVVLTSRELTVKKEDISGMEIKEQH
                     IFIEEFKKKDREKGFDLPKDPLMRLTLFDMGENRHTCVWTHHHIIMDGWCLGIVLKEFF
                     HIYYSLKNSDPLQLGSTVPYSRYIGWLGEQDKEETGVYWDGYLSDYGQTASIPLTNNRR
                     KDGVYVSEQIHFSLDPSSVEKLTALSRSLGVTLNTLFMSIWGVMLHRYNATDDAVFGSV
                     ISGRPSTIDGIESMVGLFINTIPVRVRAHGGMSFSSLVKEVQKDTLASENHGYYPLYEI
                     QNRSPLKQGLLNHILVFENYPVQIQKAVGAWQGQEENALKLGDFSMSEETNYDLNVVIV
                     PGDNFYIKFSYNASVYKQEDMLRIQGHLKKALDCILSDPDIAVENIDIVPVEEQMLIHT
                     FNKTDRSYPEKTVYELFEDQAAETPEATALVLDDTHWTYRQLDERANQMARVLKEKGAK
                     PGSIVAVMMRRSKEMAAALLGIWKAGSAYMPLDPGYPSERLSFLLDDSETSLLLTEDEL
                     ISTVPSDYAGDTVTTEEALSYKTDPLPTTIQAGKLAYLIYTSGTTGRPKGVLVDHRGIA
                     NTLQWRREEYGMSGQDTALHLFSYVFDGCVTSLFTPLLSGACVILTNDDDAKDVLAIKK
                     TIAKHRVTHLLIVPSLHRVLLEVLEKEEAKTLRVVTFAGEPVTADLLEASREICPHTEL
                     ANEYGPTENSVATTVLRHLNQESCITIGRPIANTEVCILIGNQLQPIGASGELCIGGAG
                     LAQGYYKQTELSQKAFTSHPFREGERLYRTGDAARWLQDGTLEYIGRFDDQVKIRGYRI
                     ELGEVEAVLRNIPGVKEAAVVARETSSDERELFAYIVPQKGDGLPDVHLHLAGKLPAYM
                     IPASITKINKMPLTSSGKLDRSALPEPMNMADSAHTYEPPRTIIESELTAIWKNVLNKK
                     QIGIRDDFFHLGGQSLKAATLVSRIHKKLNIQLPLSEVFIYPTVESMAAKIESLKEQTF
                     TTIAPAQSRELYPLSFSQKRMYTLHQLEENGTGYNMPAALELHGKLDRQRLKQAVTELV
                     NRHESLRTSFVIHNGEPMQQVHVSLTPEFTELQIESKSQLKQTMQSFIQPFVLTNAPLL
                     RACLIVLENDHHYLLLDMHHIAADGVSMSTLIQEFTDLYCGKTLHPLKLQYKDFAVWQK
                     EQFARQLFSKQEDYWLKQLSGLPVLELPLDKNRPLLPDFSGGTFEAEIDRETAERLHRI
                     MSETGCTLYMVLLAAYSILLSKLSGQKDIVVGSPAAGRRHADLEPVIGLFVNTLAMRSQ
                     PEGEKSFRSYLQEIKEVALTAYEHQDYPFEELTNKLGTQRELNRNPLFDAMLVLQSSED
                     FQLELPGLAISSRKLPHKASKFDLTLHAEENNEGIRCCFEYSTALFEHETVARWANHFK
                     ELLRSITADTDVKLADMQMLGGSEQRMLLDNMHHLSDYPSNKSLPDLFENWAKETPEHI
                     AVVMDDHRLTYRELNDQAERAAAMLMKKGVRSEQIVGLMTERSPDMLIGILAILKAGGA
                     YLPIDPDYPQERISFMLHDSGAEILLTHAAKKRPDGYKGEILYIEDAENEPASDMPKPP
                     IRAEQPAYIIYTSGTTGQPKGVAVEHRNVVSLLKHTELPFDFGPQDVWTLFHSYCFDFS
                     VWEMFGALLNGGTLVVVSKETARDPNAYRLLLKEEGVTVLNQTPTAFYSLMHEEQSHAD
                     ALSVRYVIFGGEALQPGMLRSWKGKYPETDLINMYGITETTVHVTYKKLADIDIAANKS
                     NIGKPLATLTAYVLDDYMNFQPIGIPGELYVGGAGVAKGYVNREELTAARFIPNPYVPG
                     DRLYRTGDIAKRLPNGELEYEGRIDNQVKVRGHRIELGEIKAALLKHSLIKEAAVITRL
                     DEQGQHTIYAYLISETDRKLNQSKIRASLKAVLPDYMIPARFMQLDSMPLTSNGKLDQK
                     ALPEPDAGTRISDDILPRNDTEKVMAEIWEELLGLEQLGVSANFFELGGDSIKALQVCA
                     RLKQHGFETTVRELFEHQTLSELSARVRKIERVISQAPVSGEMPWTPVQHWLFSQSMTS
                     VHHFNQSVMLYRADRFNSSALREVLKSLAKHHDALRIVCRNIESKPVQVNRGIDLTDEE
                     LYFFQQFDIRDDHAKATDHPAGLSSEEKRRIAETADRIQQNIQLETGPLLHAGLFRASD
                     GDHLLLAIHHLVIDGVSWRILFEDFEIGYEQALAGKSIVFPQKTDSFHDYAHQLAAYSD
                     TRGLFREIEYWTEREKQHVERLPRDYTVSSNKLKDTNVIDFELSRQDTEQLLTSVNKAY
                     TTDTNDILLAALGLSLQEWTGYDHLKISMEGHGRESYLDNIDLSRTVGWFTSIYPVLLD
                     MDVSEHTDEKERLGYHIKRTKDMMRRIPHKGVGYGVLKYVSGIWNETGNISNSPEISFN
                     YLGQFDQDIQMNSFEVSPVQTGDEISPDWERPYILDISGAVSSGCLKMHIVYNRYQYEA
                     QTIQTFAGHFKRILEDIIRHCAAKENREWSAADFSDEELTLEDLSEIMGAVNKL"
     aSDomain        5214..6119
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE37_RS20850_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="2.70E-108"
                     /label="MOE37_RS20850_Condensation_DCL.1"
                     /locus_tag="MOE37_RS20850"
                     /protein_end="309"
                     /protein_start="7"
                     /score="353.6"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIIMDG"
                     /tool="antismash"
                     /translation="QDIYPLSYMQEGMLFHSLLHGDSKAYVEQTSFTINGNLCIDSFQK
                     SLNLLVSRYDIFRTIFIKEVPDLSGPQQVVLTSRELTVKKEDISGMEIKEQHIFIEEFK
                     KKDREKGFDLPKDPLMRLTLFDMGENRHTCVWTHHHIIMDGWCLGIVLKEFFHIYYSLK
                     NSDPLQLGSTVPYSRYIGWLGEQDKEETGVYWDGYLSDYGQTASIPLTNNRRKDGVYVS
                     EQIHFSLDPSSVEKLTALSRSLGVTLNTLFMSIWGVMLHRYNATDDAVFGSVISGRPST
                     IDGIESMVGLFINTIPVRVRA"
     aSModule        5214..8318
                     /complete
                     /domains="nrpspksdomains_MOE37_RS20850_Condensation_DCL.1"
                     /domains="nrpspksdomains_MOE37_RS20850_AMP-binding.1"
                     /domains="nrpspksdomains_MOE37_RS20850_PCP.1"
                     /locus_tags="MOE37_RS20850"
                     /monomer_pairings="Tyr -> Tyr"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       5223..5264
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20850_0001"
                     /evalue="1.30E-04"
                     /label="C1_DCL_004-017"
                     /locus_tag="MOE37_RS20850"
                     /protein_end="24"
                     /protein_start="10"
                     /score="14.1"
                     /tool="antismash"
                     /translation="YPLSYMQEGMLFHS"
     CDS_motif       5286..5399
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20850_0002"
                     /evalue="9.40E-14"
                     /label="C2_DCL_024-062"
                     /locus_tag="MOE37_RS20850"
                     /protein_end="69"
                     /protein_start="31"
                     /score="43.7"
                     /tool="antismash"
                     /translation="AYVEQTSFTINGNLCIDSFQKSLNLLVSRYDIFRTIFI"
     CDS_motif       5625..5690
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20850_0003"
                     /evalue="1.20E-11"
                     /label="C3_DCL_135-156"
                     /locus_tag="MOE37_RS20850"
                     /protein_end="166"
                     /protein_start="144"
                     /score="37.0"
                     /tool="antismash"
                     /translation="HHHIIMDGWCLGIVLKEFFHIY"
     CDS_motif       6015..6110
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20850_0004"
                     /evalue="8.00E-19"
                     /label="C5_DCL_263-294"
                     /locus_tag="MOE37_RS20850"
                     /protein_end="306"
                     /protein_start="274"
                     /score="60.0"
                     /tool="antismash"
                     /translation="DAVFGSVISGRPSTIDGIESMVGLFINTIPVR"
     CDS_motif       6159..6275
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20850_0005"
                     /evalue="2.30E-18"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="MOE37_RS20850"
                     /protein_end="361"
                     /protein_start="322"
                     /score="58.6"
                     /tool="antismash"
                     /translation="QKDTLASENHGYYPLYEIQNRSPLKQGLLNHILVFENYP"
     aSDomain        6615..7793
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE37_RS20850_AMP-binding.1"
                     /evalue="6.90E-111"
                     /label="MOE37_RS20850_AMP-binding.1"
                     /locus_tag="MOE37_RS20850"
                     /protein_end="867"
                     /protein_start="474"
                     /score="362.7"
                     /specificity="substrate consensus: Tyr"
                     /tool="antismash"
                     /translation="FEDQAAETPEATALVLDDTHWTYRQLDERANQMARVLKEKGAKPG
                     SIVAVMMRRSKEMAAALLGIWKAGSAYMPLDPGYPSERLSFLLDDSETSLLLTEDELIS
                     TVPSDYAGDTVTTEEALSYKTDPLPTTIQAGKLAYLIYTSGTTGRPKGVLVDHRGIANT
                     LQWRREEYGMSGQDTALHLFSYVFDGCVTSLFTPLLSGACVILTNDDDAKDVLAIKKTI
                     AKHRVTHLLIVPSLHRVLLEVLEKEEAKTLRVVTFAGEPVTADLLEASREICPHTELAN
                     EYGPTENSVATTVLRHLNQESCITIGRPIANTEVCILIGNQLQPIGASGELCIGGAGLA
                     QGYYKQTELSQKAFTSHPFREGERLYRTGDAARWLQDGTLEYIGRFDDQVKIR"
     CDS_motif       6801..6842
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20850_0006"
                     /evalue="6.30E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="MOE37_RS20850"
                     /protein_end="550"
                     /protein_start="536"
                     /score="13.2"
                     /tool="antismash"
                     /translation="LGIWKAGSAYMPLD"
     CDS_motif       7026..7085
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20850_0007"
                     /evalue="1.60E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="MOE37_RS20850"
                     /protein_end="631"
                     /protein_start="611"
                     /score="29.7"
                     /tool="antismash"
                     /translation="AYLIYTSGTTGRPKGVLVDH"
     CDS_motif       7587..7676
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20850_0008"
                     /evalue="5.90E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="MOE37_RS20850"
                     /protein_end="828"
                     /protein_start="798"
                     /score="37.8"
                     /tool="antismash"
                     /translation="PIGASGELCIGGAGLAQGYYKQTELSQKAF"
     CDS_motif       7758..7823
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20850_0009"
                     /evalue="6.30E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="MOE37_RS20850"
                     /protein_end="877"
                     /protein_start="855"
                     /score="37.4"
                     /tool="antismash"
                     /translation="YIGRFDDQVKIRGYRIELGEVE"
     CDS_motif       8031..8057
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20850_0010"
                     /evalue="7.10E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="MOE37_RS20850"
                     /protein_end="955"
                     /protein_start="946"
                     /score="3.4"
                     /tool="antismash"
                     /translation="GKLDRSALP"
     aSDomain        8115..8318
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE37_RS20850_PCP.1"
                     /evalue="1.30E-22"
                     /label="MOE37_RS20850_PCP.1"
                     /locus_tag="MOE37_RS20850"
                     /protein_end="1042"
                     /protein_start="974"
                     /score="71.7"
                     /tool="antismash"
                     /translation="ESELTAIWKNVLNKKQIGIRDDFFHLGGQSLKAATLVSRIHKKLN
                     IQLPLSEVFIYPTVESMAAKIES"
     aSDomain        8367..9224
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE37_RS20850_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="3.60E-105"
                     /label="MOE37_RS20850_Condensation_LCL.1"
                     /locus_tag="MOE37_RS20850"
                     /protein_end="1344"
                     /protein_start="1058"
                     /score="343.2"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIAADG"
                     /tool="antismash"
                     /translation="LYPLSFSQKRMYTLHQLEENGTGYNMPAALELHGKLDRQRLKQAV
                     TELVNRHESLRTSFVIHNGEPMQQVHVSLTPEFTELQIESKSQLKQTMQSFIQPFVLTN
                     APLLRACLIVLENDHHYLLLDMHHIAADGVSMSTLIQEFTDLYCGKTLHPLKLQYKDFA
                     VWQKEQFARQLFSKQEDYWLKQLSGLPVLELPLDKNRPLLPDFSGGTFEAEIDRETAER
                     LHRIMSETGCTLYMVLLAAYSILLSKLSGQKDIVVGSPAAGRRHADLEPVIGLFVNTLA
                     MRSQP"
     aSModule        8367..12902
                     /complete
                     /domains="nrpspksdomains_MOE37_RS20850_Condensation_LCL.1"
                     /domains="nrpspksdomains_MOE37_RS20850_AMP-binding.2"
                     /domains="nrpspksdomains_MOE37_RS20850_PCP.2"
                     /domains="nrpspksdomains_MOE37_RS20850_Epimerization.1"
                     /domains="nrpspksdomains_MOE37_RS20850_TIGR01720.1"
                     /locus_tags="MOE37_RS20850"
                     /monomer_pairings="Thr -> D-Thr"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       8436..8546
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20850_0011"
                     /evalue="2.30E-18"
                     /label="C2_LCL_024-062"
                     /locus_tag="MOE37_RS20850"
                     /protein_end="1118"
                     /protein_start="1081"
                     /score="58.6"
                     /tool="antismash"
                     /translation="YNMPAALELHGKLDRQRLKQAVTELVNRHESLRTSFV"
     CDS_motif       8742..8807
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20850_0012"
                     /evalue="3.40E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="MOE37_RS20850"
                     /protein_end="1205"
                     /protein_start="1183"
                     /score="29.2"
                     /tool="antismash"
                     /translation="MHHIAADGVSMSTLIQEFTDLY"
     CDS_motif       8838..8873
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20850_0013"
                     /evalue="8.50E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="MOE37_RS20850"
                     /protein_end="1227"
                     /protein_start="1215"
                     /score="15.2"
                     /tool="antismash"
                     /translation="QYKDFAVWQKEQ"
     CDS_motif       9126..9215
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20850_0014"
                     /evalue="1.70E-15"
                     /label="C5_LCL_267-296"
                     /locus_tag="MOE37_RS20850"
                     /protein_end="1341"
                     /protein_start="1311"
                     /score="49.3"
                     /tool="antismash"
                     /translation="DIVVGSPAAGRRHADLEPVIGLFVNTLAMR"
     CDS_motif       9264..9383
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20850_0015"
                     /evalue="1.90E-16"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="MOE37_RS20850"
                     /protein_end="1397"
                     /protein_start="1357"
                     /score="52.4"
                     /tool="antismash"
                     /translation="KEVALTAYEHQDYPFEELTNKLGTQRELNRNPLFDAMLVL"
     aSDomain        9717..10907
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE37_RS20850_AMP-binding.2"
                     /evalue="1.90E-116"
                     /label="MOE37_RS20850_AMP-binding.2"
                     /locus_tag="MOE37_RS20850"
                     /protein_end="1905"
                     /protein_start="1508"
                     /score="381.0"
                     /specificity="substrate consensus: Thr"
                     /tool="antismash"
                     /translation="FENWAKETPEHIAVVMDDHRLTYRELNDQAERAAAMLMKKGVRSE
                     QIVGLMTERSPDMLIGILAILKAGGAYLPIDPDYPQERISFMLHDSGAEILLTHAAKKR
                     PDGYKGEILYIEDAENEPASDMPKPPIRAEQPAYIIYTSGTTGQPKGVAVEHRNVVSLL
                     KHTELPFDFGPQDVWTLFHSYCFDFSVWEMFGALLNGGTLVVVSKETARDPNAYRLLLK
                     EEGVTVLNQTPTAFYSLMHEEQSHADALSVRYVIFGGEALQPGMLRSWKGKYPETDLIN
                     MYGITETTVHVTYKKLADIDIAANKSNIGKPLATLTAYVLDDYMNFQPIGIPGELYVGG
                     AGVAKGYVNREELTAARFIPNPYVPGDRLYRTGDIAKRLPNGELEYEGRIDNQVKVR"
     CDS_motif       9903..9944
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20850_0016"
                     /evalue="2.20E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="MOE37_RS20850"
                     /protein_end="1584"
                     /protein_start="1570"
                     /score="17.6"
                     /tool="antismash"
                     /translation="LAILKAGGAYLPID"
     CDS_motif       10125..10184
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20850_0017"
                     /evalue="3.90E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="MOE37_RS20850"
                     /protein_end="1664"
                     /protein_start="1644"
                     /score="31.6"
                     /tool="antismash"
                     /translation="AYIIYTSGTTGQPKGVAVEH"
     CDS_motif       10701..10790
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20850_0018"
                     /evalue="7.00E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="MOE37_RS20850"
                     /protein_end="1866"
                     /protein_start="1836"
                     /score="50.3"
                     /tool="antismash"
                     /translation="PIGIPGELYVGGAGVAKGYVNREELTAARF"
     CDS_motif       10875..10934
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20850_0019"
                     /evalue="3.80E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="MOE37_RS20850"
                     /protein_end="1914"
                     /protein_start="1894"
                     /score="31.9"
                     /tool="antismash"
                     /translation="EGRIDNQVKVRGHRIELGEI"
     CDS_motif       11151..11177
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20850_0020"
                     /evalue="2.90E+00"
                     /label="NRPS-A_a10"
                     /locus_tag="MOE37_RS20850"
                     /protein_end="1995"
                     /protein_start="1986"
                     /score="1.8"
                     /tool="antismash"
                     /translation="GKLDQKALP"
     aSDomain        11232..11429
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE37_RS20850_PCP.2"
                     /evalue="1.20E-21"
                     /label="MOE37_RS20850_PCP.2"
                     /locus_tag="MOE37_RS20850"
                     /protein_end="2079"
                     /protein_start="2013"
                     /score="68.6"
                     /tool="antismash"
                     /translation="EKVMAEIWEELLGLEQLGVSANFFELGGDSIKALQVCARLKQHGF
                     ETTVRELFEHQTLSELSARVR"
     aSDomain        11466..12413
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE37_RS20850_Epimerization.1"
                     /evalue="2.80E-146"
                     /label="MOE37_RS20850_Epimerization.1"
                     /locus_tag="MOE37_RS20850"
                     /protein_end="2407"
                     /protein_start="2091"
                     /score="480.3"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLVIDG"
                     /tool="antismash"
                     /translation="GEMPWTPVQHWLFSQSMTSVHHFNQSVMLYRADRFNSSALREVLK
                     SLAKHHDALRIVCRNIESKPVQVNRGIDLTDEELYFFQQFDIRDDHAKATDHPAGLSSE
                     EKRRIAETADRIQQNIQLETGPLLHAGLFRASDGDHLLLAIHHLVIDGVSWRILFEDFE
                     IGYEQALAGKSIVFPQKTDSFHDYAHQLAAYSDTRGLFREIEYWTEREKQHVERLPRDY
                     TVSSNKLKDTNVIDFELSRQDTEQLLTSVNKAYTTDTNDILLAALGLSLQEWTGYDHLK
                     ISMEGHGRESYLDNIDLSRTVGWFTSIYPVLLDMD"
     CDS_motif       11886..11951
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20850_0021"
                     /evalue="1.80E-11"
                     /label="NRPS-E2"
                     /locus_tag="MOE37_RS20850"
                     /protein_end="2253"
                     /protein_start="2231"
                     /score="36.1"
                     /tool="antismash"
                     /translation="LLLAIHHLVIDGVSWRILFEDF"
     CDS_motif       12354..12404
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20850_0022"
                     /evalue="3.60E-09"
                     /label="NRPS-E5"
                     /locus_tag="MOE37_RS20850"
                     /protein_end="2404"
                     /protein_start="2387"
                     /score="28.5"
                     /tool="antismash"
                     /translation="DLSRTVGWFTSIYPVLL"
     aSDomain        12444..12902
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE37_RS20850_TIGR01720.1"
                     /evalue="7.30E-50"
                     /label="MOE37_RS20850_TIGR01720.1"
                     /locus_tag="MOE37_RS20850"
                     /protein_end="2570"
                     /protein_start="2417"
                     /score="160.8"
                     /tool="antismash"
                     /translation="LGYHIKRTKDMMRRIPHKGVGYGVLKYVSGIWNETGNISNSPEIS
                     FNYLGQFDQDIQMNSFEVSPVQTGDEISPDWERPYILDISGAVSSGCLKMHIVYNRYQY
                     EAQTIQTFAGHFKRILEDIIRHCAAKENREWSAADFSDEELTLEDLSEI"
     CDS_motif       12465..12524
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20850_0023"
                     /evalue="5.70E-09"
                     /label="NRPS-E6"
                     /locus_tag="MOE37_RS20850"
                     /protein_end="2444"
                     /protein_start="2424"
                     /score="28.2"
                     /tool="antismash"
                     /translation="TKDMMRRIPHKGVGYGVLKY"
     aSDomain        12945..13034
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE37_RS20855_NRPS-COM_Nterm.1"
                     /evalue="4.10E-16"
                     /label="MOE37_RS20855_NRPS-COM_Nterm.1"
                     /locus_tag="MOE37_RS20855"
                     /protein_end="30"
                     /protein_start="0"
                     /score="49.9"
                     /tool="antismash"
                     /translation="MSQQSEIQDIYPLSFMQEGMLFHSLFDEQS"
     gene            12945..>14982
                     /locus_tag="MOE37_RS20855"
                     /old_locus_tag="MOE37_20800"
     CDS             12945..>14982
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (0-30). E-value: 4.1e-16.
                     Score: 49.9. Matches aSDomain:
                     nrpspksdomains_MOE37_RS20855_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (7-304). E-value:
                     1.7e-117. Score: 383.8. Matches aSDomain:
                     nrpspksdomains_MOE37_RS20855_Condensation_DCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007611861.1"
                     /locus_tag="MOE37_RS20855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOE37_20800"
                     /product="condensation domain-containing protein"
                     /protein_id="WP_268533748.1"
                     /sec_met_domain="Condensation (E-value: 4.1e-91, bitscore:
                     292.8, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.6e-51, bitscore:
                     162.1, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQQSEIQDIYPLSFMQEGMLFHSLFDEQSRAYFEQASFTINGRL
                     DLERFQKSMDAIVGRYDIFRTTFIHKNVAKPRQVVLKSRPCSVQFEDISHLDKPDEEKY
                     IETFRQQDKSKGFDLQTDVLMRVSILKLAPERYVCIWSHHHILMDGWCLGIVIKDFLHM
                     YQALGEGRHPYLPPVQPYGKYIKWLMRQDREEAAKYWKERLQDIEKTSSLPRKSVQTSE
                     GKLQQAVFTISEQQTAGLQQIAAASGATLSTVFQALWGLMLQRFNNSDDSVFGSVISGR
                     PTELADVEGMVGLFINTVPVRIQSGALSFSDLVRHMQKELLKAEAYSYFPLYDIQAQSA
                     LKQELIDHIIVFENVPTQQEIEGLNQTGAFDFSVEDFSMAEETNYGCSIKVIPGSSLYV
                     RINFHTDLYDTSMMEEIEGYMQQMIASVIADPDIRASQIPLLNESKTRQIVSEFNKTEA
                     VSPIAPTLHGLFTRQAALTPDRPAIHFANGSLTYGELDAYSNRLAVRLAAKGVTKESIV
                     GILAERSPEMMIAVLAVLKAGGAYLPLDPAYPDGRLSYMLKDSGAALMLTQSGLTVPDF
                     SGETLEVDMEAPVDGNPSEVPAGTADSGSLAYLIYTSGSTGQPKGVAVEHRQAVSFLTG
                     MQRQFPLHKKDVIVLKTSFSFDASVWQLFWWTLSGASTYLLPSG"
     aSDomain        12966..13856
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOE37_RS20855_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="1.70E-117"
                     /label="MOE37_RS20855_Condensation_DCL.1"
                     /locus_tag="MOE37_RS20855"
                     /protein_end="304"
                     /protein_start="7"
                     /score="383.8"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHILMDG"
                     /tool="antismash"
                     /translation="QDIYPLSFMQEGMLFHSLFDEQSRAYFEQASFTINGRLDLERFQK
                     SMDAIVGRYDIFRTTFIHKNVAKPRQVVLKSRPCSVQFEDISHLDKPDEEKYIETFRQQ
                     DKSKGFDLQTDVLMRVSILKLAPERYVCIWSHHHILMDGWCLGIVIKDFLHMYQALGEG
                     RHPYLPPVQPYGKYIKWLMRQDREEAAKYWKERLQDIEKTSSLPRKSVQTSEGKLQQAV
                     FTISEQQTAGLQQIAAASGATLSTVFQALWGLMLQRFNNSDDSVFGSVISGRPTELADV
                     EGMVGLFINTVPVRIQ"
     CDS_motif       12975..13016
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20855_0001"
                     /evalue="3.70E-05"
                     /label="C1_DCL_004-017"
                     /locus_tag="MOE37_RS20855"
                     /protein_end="24"
                     /protein_start="10"
                     /score="15.5"
                     /tool="antismash"
                     /translation="YPLSFMQEGMLFHS"
     CDS_motif       13038..13154
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20855_0002"
                     /evalue="3.10E-17"
                     /label="C2_DCL_024-062"
                     /locus_tag="MOE37_RS20855"
                     /protein_end="70"
                     /protein_start="31"
                     /score="54.8"
                     /tool="antismash"
                     /translation="AYFEQASFTINGRLDLERFQKSMDAIVGRYDIFRTTFIH"
     CDS_motif       13371..13436
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20855_0003"
                     /evalue="9.00E-11"
                     /label="C3_DCL_135-156"
                     /locus_tag="MOE37_RS20855"
                     /protein_end="164"
                     /protein_start="142"
                     /score="34.2"
                     /tool="antismash"
                     /translation="HHHILMDGWCLGIVIKDFLHMY"
     CDS_motif       13482..13520
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20855_0004"
                     /evalue="3.30E-03"
                     /label="C4_DCL_171-183"
                     /locus_tag="MOE37_RS20855"
                     /protein_end="192"
                     /protein_start="179"
                     /score="10.2"
                     /tool="antismash"
                     /translation="PYGKYIKWLMRQD"
     CDS_motif       13755..13850
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20855_0005"
                     /evalue="4.30E-19"
                     /label="C5_DCL_263-294"
                     /locus_tag="MOE37_RS20855"
                     /protein_end="302"
                     /protein_start="270"
                     /score="60.9"
                     /tool="antismash"
                     /translation="DSVFGSVISGRPTELADVEGMVGLFINTVPVR"
     CDS_motif       13896..14012
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20855_0006"
                     /evalue="5.90E-19"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="MOE37_RS20855"
                     /protein_end="356"
                     /protein_start="317"
                     /score="60.5"
                     /tool="antismash"
                     /translation="QKELLKAEAYSYFPLYDIQAQSALKQELIDHIIVFENVP"
     CDS_motif       14538..14579
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20855_0007"
                     /evalue="3.90E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="MOE37_RS20855"
                     /protein_end="545"
                     /protein_start="531"
                     /score="19.8"
                     /tool="antismash"
                     /translation="LAVLKAGGAYLPLD"
     CDS_motif       14763..14822
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOE37_RS20855_0008"
                     /evalue="7.40E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="MOE37_RS20855"
                     /protein_end="626"
                     /protein_start="606"
                     /score="33.8"
                     /tool="antismash"
                     /translation="AYLIYTSGSTGQPKGVAVEH"
ORIGIN
        1 cggatgtaca aaacgggaga tctggcgcgc tggctgccgg acggacaggt tgagttcctc
       61 ggccgtttgg acgatcaagt gaaaatccgc ggctaccgga tcgaacccgg cgaaattgaa
      121 tcagctctcc gaaacttgga aggcgtgcag gaagcagccg tcatcacccg cgcagacagc
      181 ggggaggcag agctatgcgc ttatgtccag gggcgtgata aaaacgacgt gcgggcacag
      241 cttgcgctcg tgctgcccgg ctatatgatc cccgctcatt ttgtgcaaat caacacatgg
      301 ccgatcacac caagcgggaa gcttgaccgg aaggctttgc ccgctcctga tggagcggct
      361 ggtcaagaat catacaaggc accaagaaat cttaccgaaa tgaagctggc ccagctttgg
      421 gaagacgtgc tgaaaaacgg tcctgtcggt atcacagacg actttttcga ccggggaggc
      481 cactcgttaa aagcaacggc actgatttct cgaatcgcca aggcattcgg cgtccaagtg
      541 ccgcttaaag acatatttgc ccgaccgacc gtagaagggc tggcttctgt catccgcgag
      601 ttggaggaaa gcccgtatgc ggcgattgaa ccggccgaaa aacgggacac ctatccggtc
      661 tcctcggcgc aaaaacggat gtatgtcctt cagcagctgg aagacggagg cgtcggctac
      721 aacatgcctg cggtgcttga gctggaaggc aagctcgacc gtaaacgaat ggaggcagct
      781 ttccaagcgc tgatcagccg ccatgagtcg ctccggacgt cctttgaaac cggaaacggc
      841 ggggagccga tccagcgcat ccatcatgag gtgccgttta cggtgaccga agagaactcg
      901 gctgatgcgt ttgtacgtcc ctttgttctc agccaggctc cgcttttcag agcgggactc
      961 gtaaaagaaa caaacgagcg gcatgtcctt ttggtcgaca tgcatcatat catttctgac
     1021 ggcgtctcag tcaatacgct cattcaggaa tttggagaat tgtacgccga gcggaagctt
     1081 gagccgctgc gcatccaata caaagattac gccgtatggc agcaggactt caaaaaaggc
     1141 gacacatatg agaagcagga atcttattgg gtgaagcagc tcggaggcga gctgcctgtg
     1201 cttgaactgc cggcggacaa gccccgtccg gcggtgcgaa gcttcgccgg tgacaagatc
     1261 tcctttactc tggaccaaga agtcacgtcc ggcctgaacc gcctcgcgcg ggaaaacggc
     1321 agcaccctgt atatggtgct tcttgcggcc tactcagctc ttttgtcacg cctcagcggg
     1381 caagaggaga ttgtggtcgg atcgccaatc gccggccgtc cgcatgaaga ccttgaacct
     1441 gtgctcggca tgttcgtgaa cacgttggcg cttcggacac gcccggaggg cggaaagggt
     1501 ttcacagact atttgcagga agtccgtcag acagcactgg aagcctatga acatcaagat
     1561 tatccgtttg aagaactggt cgaaaagcta ggcgttcaga gagacatgag ccgcaatccg
     1621 ctgtttgatg cgatgtttat tcttcaaaac atggaacaac acgacataca tctgccagaa
     1681 atagaagtca gacgcaacag cttgattcat tcgatctccg tgtttgatct gactttgtcg
     1741 gcggtagaat caggcgggca aatagaatgt gaaatggaat tcagcacaga tgttttctta
     1801 aaagacacgg tggaacggtg gagctctcat ttgatcgaac ttctgaggtc tgtgacggcc
     1861 cgtcccgata cagtcctcgc acggcttgaa atattggaag aacaagaaaa acggatgatt
     1921 gcagaggggt tcaatgacac acaaattgaa ttttcccaaa gtgcagattt gtttcatcat
     1981 atattcgaag ctaagacaga agaaacaccg catcacatcg ctattatcga gggagaaaaa
     2041 caaataacct atcatcagct taatgaacgt gcaaatcgtc tggccagaac gctgagaaga
     2101 aagggaacgg gcccaaatta ctcggttgct attttagcaa atcgatcaat tgatgcagtg
     2161 gtcagtattc tggcggttct gaaatccggc ggcacctata ttccgattga tacgcattat
     2221 cccgaaggaa gaatcagaaa tcttcttcag gatagcgggg cagtcacgct tctcgttcag
     2281 caggatctca aacacctgat tgcagatttg accggtatag gcgtttcgca aattttttat
     2341 ctagacgatg agtatctgta cgattcggat gcgtccaatc tgattccagc ggctgggccg
     2401 gaagatgcag catatatcat atacacatcc gggacaacag gaaccccaaa aggagttgtc
     2461 ataaagaatc gaagctttac tcatgccgct cttgcctggc gtgagatcta ccaattggag
     2521 cgtttccctg tcaggctgct tcaaatggcg agcttttcat ttgatgtctt ctcgggtgac
     2581 ttggcacgga ctttattaaa cgggggcact ctagtgattt gtccggatga agtccggctg
     2641 gagcctgctg agctgtacgc attattgatt cagcagcgta ttacattaat ggagtcaaca
     2701 ccggctctca tggttccttt tatggattat gtatatcgca gcaatctttc gctgccagat
     2761 ttacgcttgc ttgttcttgg ttcagatact atcaaagctc aagacttcaa aacgctctca
     2821 cagcgttttg gcaaacagat gcgtttgatc aatagctatg gcgtgacaga agccaccatt
     2881 gattccagtt actatgaagc taatatgggt gccgctgtga acgaggaata tgtaccaatc
     2941 ggcgtaccgc tgccaaatgt ccacatgtac gtactcagca attacgatca aatacagccg
     3001 atcggtgttg ccggagaact ttgtatcggc ggagccggcg tggcgaaagg gtatcacggt
     3061 aaacctgaat tgacggaagc caaattcact gaacatccat ttatatctga tgaaaagata
     3121 tacagaacag gagatcaagc atgctggctt cctgatggca ctgtgcgttt cctcggccgt
     3181 atggacaacc aggtgaaaat caagggctac agaattgaag cgggagaaat tgaaagtgta
     3241 ctgcttcaga cgggcatggt caaagaggct gcagcggcag tccaaaagga tccccagggg
     3301 cagtcttatc tagcggcata tatagtgcct tcggatgttg atacgtcagc tctccgtgac
     3361 gctctggcga aggaattacc tgcatatatg gttccatctc atttcatggc tctggataaa
     3421 ataccgctga cgcctaacgg caaagtggac agaaaggcat tgcctgttcc gaacgaaggc
     3481 ttgcgacagg cttataccgc tccatgcacc gacaagcaaa caatgatggc cggcatttgg
     3541 gaggacgtgc ttagtatttc gcgcgtcggc atccatgatt cctttttcga tcttggcgga
     3601 gattccatta aggcgctgca agtatcagcc aggcttgctg cagaaggctg gaagatgacg
     3661 attagagact tatttcaatt tccaaccatt cagaagctga cagatcatat tacaccggcc
     3721 gtttctgcag ccgatcaggg acctgttgaa ggaaaagctg ttctcacgcc aatacagcgg
     3781 agatttttca gtcagccgga tgcttttcgg taccattaca atcagtcagt catgttattc
     3841 aatgagatag gatttagaga cgacgctctc cgtcaagcgc ttcgccgctt ggcagtgcat
     3901 cacgatgcgc ttcgcatggt ttttacaaaa gatcaggcag ggcttatcat tcagcataac
     3961 cgcgggactg accttcagga tgaggaactg tatcatcttc atatcacaga ttggactaaa
     4021 gaaccgcaag ctcttatcca tgcagaagaa caaattgcaa aagaagaagc ccgtattcaa
     4081 aaagcgatgc ggcttgaaca agggcctttg ctccaagcgg gattgttcaa aacggcggat
     4141 ggtgattacc ttcttatcgc tatccatcat cttgtagtgg atggcgtctc ttggcggatt
     4201 ttgctggagg acctttcagc agcttatcag catgcgctcg aaggaagaga gatcaaattg
     4261 cctcctaaaa gtgattcgta cctctcttac gcaaacgctc ttgtgcaatc agcggaaaac
     4321 agaaaattat tgcaggaaaa gccttattgg gaaagtgtta taaatgcaca aacggctgtt
     4381 ttgcccaaag accagcctta tgcttctgaa ggactgcaaa aaaatgccgg cacagcatca
     4441 ttgatacttt caggcgattg gaccagtaag ctgctatttg aaactcagca agcctatggc
     4501 acagatgtaa atgaactgtt actgactgga ttgggcatgg cgttggccga gtggacagga
     4561 aacgaacaaa ttgtaatcag cactgaagga cacggcaggg aaggacacgt ttccgatatt
     4621 gatatttcac gaacggtggg ctggtttact tctgtctatc ctgtccttct taacatggac
     4681 gcaaatcatt cagacgataa gctcgccagc cgaatcaaag cgacaaagga catgctgaga
     4741 agagtgccga atcaaggaac cggctatggg ctattagaat acatgacaga aaatgaagac
     4801 tggaatagag aaccagaggt cagtttcaat tatctcggac agtttaacga tatagaggat
     4861 tcaaagacgc ttcgaatgtc ctcttaccag ccgcgttatg aaatagccgg cgagcggtac
     4921 agagagtatg cgttggacat caatgccatg ataatcggcg gacagctaca agtgaaagca
     4981 gtgtacactc aggtgtttca tcatagaacc atcgaactct tcatggagag ctttcgaaag
     5041 catatcatca gtgccattga acattgttcg ggaaaaaagg aacgtgaaaa aacgctgagc
     5101 gatttcagca acaaagaaat gacatcagca gcactatcaa gcatcgcaaa tcttgtaaaa
     5161 gatctttaac tttgaaaaaa ggtgtgtgtg agatgacgca agctacaggg attcaagaca
     5221 tttacccttt atcgtatatg caggaaggta tgctgtttca ttcattgctt catggtgact
     5281 cgaaagctta tgtggagcag acatcgttca ccattaacgg aaatctatgt atagactcat
     5341 ttcaaaaaag cttgaatctg ctggtttctc ggtatgatat tttcagaacg atttttatta
     5401 aggaggttcc tgacctctcc ggcccgcagc aagttgttct gacaagtcgt gaactgactg
     5461 tgaaaaaaga agacatttct ggcatggaga taaaagaaca gcacattttc attgaagaat
     5521 ttaagaagaa ggacagagaa aaaggatttg atttgccaaa agacccgctc atgcggctta
     5581 ctctttttga tatgggtgaa aaccgacata cttgtgtatg gacacatcac cacatcatca
     5641 tggacggctg gtgtctgggc attgttctga aggaattctt tcatatctat tattctctga
     5701 aaaacagcga cccgctgcag ctcggcagta cggttcccta cagcagatat attggatggc
     5761 tcggcgaaca ggacaaggaa gaaacgggtg tgtattggga cggctacctg agtgattacg
     5821 gccagacagc ttccattccg cttacgaaca acaggcgtaa ggacggtgtg tatgtatcgg
     5881 aacagattca tttctctctt gatccatctt ccgttgaaaa actcacagcc ttatcccgga
     5941 gcttgggagt gactttaaac accctattta tgagtatatg gggagtcatg ctgcatagat
     6001 acaacgcaac ggatgatgcc gtgttcggct ctgtcatttc cggccgccct tcaacgattg
     6061 acggaataga atcaatggtc ggtctgttta ttaacaccat tcccgttcgg gtgcgcgcgc
     6121 acggagggat gtcattttct tctcttgtca aagaagtgca aaaggacaca ttagcatctg
     6181 aaaaccatgg ttattatcct ctctatgaga ttcagaatcg aagccctcta aaacagggct
     6241 tactcaatca cattcttgtg tttgaaaatt accctgtcca gatacaaaag gcagtcggcg
     6301 cttggcaggg ccaagaagaa aacgcattga agcttgggga tttttcaatg tcagaagaaa
     6361 ccaattatga cctaaatgtc gtgattgtgc ctggagataa cttttatata aaattcagct
     6421 acaatgcttc cgtgtataag caggaagata tgcttcgaat tcagggccac ttgaaaaaag
     6481 cgctggattg cattctgtct gatccggata ttgcagtcga gaacattgat attgtacctg
     6541 tcgaggaaca aatgctcatt catacattta acaagacgga cagatcttac ccggaaaaaa
     6601 cggtttacga attatttgaa gaccaggccg ccgagactcc tgaagcgaca gctcttgtgc
     6661 tggacgatac gcactggaca tatcgccaat tagacgaaag ggcgaaccag atggcgcgtg
     6721 tgcttaagga aaagggagca aaacctggca gcatcgtggc cgtcatgatg cgacggtcaa
     6781 aggaaatggc agcggcactg ctcgggattt ggaaagcggg cagtgcatat atgcctcttg
     6841 atcccggcta tccgtctgaa cggctgtctt ttctgttaga tgacagcgaa acatctttgc
     6901 tgctgacaga ggatgaactc atttcgactg tgccttcgga ttatgccgga gacactgtga
     6961 caacagagga agccttgtca tataaaaccg atccgcttcc aacgacaata caagccggaa
     7021 agctggccta tctcatctac acttcaggaa cgaccgggcg gcctaaagga gttcttgtgg
     7081 accaccgtgg aattgcaaat acattgcaat ggagacggga agagtacggc atgagcggtc
     7141 aagataccgc gctgcacctg ttttcatatg tctttgacgg ctgcgtgacg agcttgttca
     7201 ctccgctttt atcaggtgcc tgtgtgattt tgacaaatga cgatgatgcg aaagatgtac
     7261 ttgcaattaa gaaaaccata gccaaacatc gggtcactca tctgctgatt gtgccttcac
     7321 tgcatcgggt tttgctggaa gttttagaaa aagaagaagc caagaccctt cgcgttgtga
     7381 catttgcggg agagccggtc accgcagatt tacttgaagc cagccgggaa atttgtccgc
     7441 acacagaatt agcaaacgaa tacgggccga cagaaaatag tgttgcgacg accgtgcttc
     7501 gtcatctgaa tcaggaatca tgtattacga tcgggcgtcc gattgccaat accgaagtgt
     7561 gtattttaat cggtaaccaa ttgcagccga taggcgcatc gggtgaactt tgtatcggag
     7621 gcgcaggttt ggcgcaaggc tactataaac agactgaatt gtcgcaaaaa gcatttacat
     7681 cacatccgtt tcgagaagga gaacgcctat accggacggg agatgcggcg cgctggctgc
     7741 aggacggaac gttagaatat atcgggcgtt ttgatgacca agtgaaaatt agaggctacc
     7801 ggattgaatt gggggaagta gaagcagttc ttcgaaacat accgggagta aaagaagcgg
     7861 cggtcgtagc ccgtgaaacc tcttcagacg aacgggaact ttttgcttat atcgttccgc
     7921 aaaagggaga cgggcttcca gacgtacatc ttcatcttgc tgggaaatta ccggcttata
     7981 tgattccggc gagtattaca aaaataaaca agatgccgtt aacttcaagc ggaaaactgg
     8041 accgctcagc tctgccggaa ccgatgaaca tggcggactc agctcatacg tatgaaccgc
     8101 ctcgcacgat tattgaatct gaattaaccg cgatttggaa aaacgtgctg aataagaagc
     8161 agatcggcat acgcgatgat ttcttccact taggcgggca gtcattaaaa gccgctacac
     8221 ttgtatcaag aatacataaa aagctgaata tccagctgcc gctcagcgaa gtgtttatat
     8281 atccgacagt agaaagcatg gcagctaaaa tcgaaagctt aaaagaacaa acatttacaa
     8341 caattgctcc agcgcaatca agagaactgt acccgctgtc tttttcacag aaaaggatgt
     8401 atacccttca tcaactggag gagaacggta caggatacaa tatgccggca gcgctggaac
     8461 tgcacggaaa gctcgatcgc cagcggctga aacaggctgt cacggaactt gtgaaccggc
     8521 atgaatcact ccgcacttcg tttgtcatac acaatggtga accgatgcag caagtccatg
     8581 taagcctgac accggagttt accgagcttc agattgaatc aaaaagccag ctaaaacaga
     8641 cgatgcagtc atttatacag ccgtttgttt tgacaaacgc accgttgctt agagcatgct
     8701 taatcgtttt agaaaatgat catcattatc tgttgctgga tatgcatcac attgctgctg
     8761 acggtgtctc tatgagcaca cttatccaag aattcacaga cctgtactgc ggcaagacgc
     8821 ttcatccatt aaagctgcag tacaaggatt ttgcagtctg gcaaaaagag cagtttgccc
     8881 ggcagttatt cagcaaacag gaagattact ggctgaaaca gctcagcggc ctgcctgtat
     8941 tagaactgcc gcttgataaa aaccgtccgc ttctgcctga tttcagcggc gggacatttg
     9001 aagcagaaat tgatcgcgag actgcagaac ggctacatcg tatcatgtct gaaacgggct
     9061 gtacgttgta tatggttctt cttgctgcct attcgattct gctttctaag ctaagcggac
     9121 aaaaggatat tgttgtcggt tcacctgctg ccggaagacg gcatgccgat ttggagccgg
     9181 tcatcggact gtttgtgaat acccttgcga tgcggagcca gcctgaagga gaaaagtctt
     9241 tcagatctta tttgcaagaa attaaagaag tggcccttac tgcatatgaa catcaggatt
     9301 atccttttga ggagctcaca aacaagctcg gaactcagag agaattgaat cgcaatccgc
     9361 ttttcgatgc gatgctggtg cttcaaagca gtgaagattt tcagcttgaa ttgcccgggc
     9421 tggcaatatc ttctcgcaag ctgccacata aggcgtctaa attcgatctg accttgcacg
     9481 ctgaggaaaa caacgaagga attcgctgct gctttgagta cagcaccgca ttatttgagc
     9541 acgaaaccgt tgcgcgctgg gccaatcatt tcaaggaact gctgagaagt ataacggccg
     9601 atacagacgt gaagctggct gatatgcaga tgcttggagg ctcagagcaa cgtatgctgt
     9661 tggacaatat gcatcattta tctgactatc cgagcaataa aagtcttccg gatttatttg
     9721 aaaattgggc aaaagaaaca ccggagcata tagcagtggt gatggacgat caccggctga
     9781 cttaccgcga gctgaatgat caagcagaac gggcagcagc tatgctgatg aaaaagggag
     9841 tacgctctga acaaattgtc ggcttgatga cagaacgctc acccgatatg ctgatcggaa
     9901 ttcttgccat tctgaaagcg ggcggagcct acctgccgat tgatcccgat tatcctcagg
     9961 aacgtatcag tttcatgctt catgacagcg gagcagagat tttgctgacc catgctgcga
    10021 aaaagagacc tgacggttat aaaggagaaa ttttgtatat agaagatgct gagaacgaac
    10081 cagccagtga tatgccaaaa ccgcctatcc gcgcagaaca gcctgcatat atcatctaca
    10141 catcaggtac gaccggccag ccaaagggag ttgcagtcga gcatcgcaat gtagtcagct
    10201 tgttgaaaca tacagaactg ccttttgatt ttggtcctca ggatgtgtgg acattgttcc
    10261 attcatattg ctttgatttt tctgtgtggg aaatgttcgg cgcactctta aacggcggca
    10321 cattagttgt ggtttcaaaa gaaacagccc gggacccgaa tgcttatcgg ctgctgctga
    10381 aagaagaagg ggtaaccgtc ctgaatcaga cgccgacggc tttttacagt ctcatgcatg
    10441 aagaacaatc tcatgccgat gcattaagcg tccgttacgt cattttcggg ggggaggcat
    10501 tacagcccgg aatgctgcgc agctggaaag gcaaatatcc ggagacagac ctgattaata
    10561 tgtacggcat tacagaaacg actgtccatg tgacgtataa aaagctggcc gatatagata
    10621 tcgcagcgaa taaaagcaat atcgggaaac cgctcgcaac ccttacagca tatgtattgg
    10681 acgattatat gaattttcag cctataggga tccccggcga gctgtatgtt ggcggcgctg
    10741 gagtagcgaa gggatatgta aacagggaag agctgactgc agcaagattt attccgaatc
    10801 cctatgtgcc tggcgacagg ctgtaccgca cgggagacat cgccaagcgg ctgccgaatg
    10861 gcgagcttga atatgaggga cggatagata accaggtgaa agtcagaggg caccgtatag
    10921 aactcggtga aattaaagcg gctcttctca aacattcact gattaaagaa gcggctgtaa
    10981 ttacaaggct tgatgaacaa ggacagcata ccatttatgc ttatctgatc tcagagacag
    11041 atcgcaaact gaatcaatca aaaatccgcg cctccctgaa agccgttttg ccagattata
    11101 tgataccggc ccgattcatg cagcttgaca gcatgccgct tacaagtaac ggaaagcttg
    11161 atcagaaggc gctccctgaa ccagatgcgg gcacccgtat atctgatgat attttgccga
    11221 gaaatgacac tgaaaaggtg atggctgaga tttgggagga actgctgggg cttgagcagc
    11281 ttggtgtcag cgcgaatttc tttgaacttg gcggagattc aattaaagcg ctgcaagtct
    11341 gtgcaaggct gaagcagcac gggtttgaaa caacagtgcg ggaactgttt gagcatcaga
    11401 cattgagcga gctgtccgca cgtgtccgta aaattgaacg tgtgatcagc caagcgcctg
    11461 ttagcggtga aatgccttgg acacctgtac agcattggct tttttcccag tcaatgacgt
    11521 cagttcacca ttttaatcag tccgtcatgc tgtatcgagc tgaccgattt aacagcagcg
    11581 ctctcagaga agttctgaaa agtttggcaa agcaccatga cgcattacga atcgtctgcc
    11641 ggaatataga gagcaagccg gtgcaggtta accgaggcat tgatctcact gatgaagaat
    11701 tatatttctt tcaacagttt gatataagag atgatcatgc aaaagcaact gatcatccgg
    11761 ccggtctgtc aagtgaggaa aagagacgga ttgcagagac cgcagatcgt atccagcaaa
    11821 acattcaatt ggaaacaggt cctctgcttc atgccggttt gttccgtgct tcagacggag
    11881 accatttgct gctcgctatt catcatctcg ttatcgacgg tgtatcttgg cgaattttgt
    11941 ttgaagattt cgagattggc tatgaacaag cgctggcagg aaaatcaatc gtattcccgc
    12001 aaaaaacgga ttcttttcat gattatgccc atcaattggc tgcctactct gacacacgcg
    12061 ggcttttccg tgaaatagag tactggacag agcgtgaaaa acagcatgtt gaacgccttc
    12121 ctagagatta caccgtgtca tctaataagc tcaaagatac caatgtaatt gatttcgagc
    12181 tttccagaca ggacacagag cagctgttaa catccgtcaa caaggcttac accactgaca
    12241 ccaatgatat cctgcttgcc gctttagggc tttccttaca ggaatggaca ggctatgatc
    12301 atctgaaaat cagcatggaa ggacacggca gggaatcata ccttgataac attgatctaa
    12361 gccgaacagt cgggtggttc acttcgattt atccggtttt gcttgacatg gatgtttctg
    12421 aacataccga tgaaaaagag cggcttggct accatattaa acgtacgaaa gacatgatgc
    12481 gccgcatccc tcataaaggc gtcggctacg gagttctaaa atacgtaagc ggtatttgga
    12541 atgagacagg gaatatttca aacagccctg aaatcagttt taactattta ggccagtttg
    12601 atcaagatat acaaatgaat tcgtttgaag tttctccggt tcaaacagga gacgagataa
    12661 gcccggattg ggagcgccct tatattcttg atattagcgg cgccgtttcg tcaggatgtc
    12721 tgaaaatgca catcgtctat aaccgctatc aatatgaggc gcagacgatc caaacattcg
    12781 ccggacattt taaacgtatt ctcgaagaca tcatacggca ctgtgcggct aaagaaaacc
    12841 gcgaatggag tgccgctgat ttcagtgatg aggagttaac gctagaagac ctcagtgaaa
    12901 ttatgggagc cgtcaacaaa ctatagaaaa aggagaggcg ctacatgtcg caacaatccg
    12961 aaattcagga tatttatccc ctgtcattta tgcaggaggg catgcttttt cattcgctgt
    13021 ttgatgaaca atcaagagcc tattttgaac aggcatcctt taccatcaac ggaaggctag
    13081 acttggaacg cttccaaaaa agtatggatg ccattgttgg ccgatatgac atctttcgta
    13141 caactttcat tcacaaaaat gtagccaagc ctaggcaagt cgtgctcaaa agccgtccat
    13201 gcagcgttca gtttgaggat atttcccatc ttgataagcc agatgaagag aaatatatcg
    13261 aaaccttccg gcaacaggat aagtccaaag gctttgattt gcaaacagat gtccttatga
    13321 gggtatccat tttgaaattg gcgcctgagc gctatgtctg tatttggagc catcaccata
    13381 ttttgatgga cggatggtgc cttggcattg tcattaaaga ttttctccac atgtatcagg
    13441 ccctgggcga agggcgtcat ccttaccttc ctccggttca gccgtacgga aaatatatca
    13501 agtggctgat gcggcaagac cgcgaagagg cggcaaagta ttggaaagag cggcttcaag
    13561 atattgaaaa gacatcatcc ttgccaagaa aaagtgttca aacatcagaa ggaaaattac
    13621 agcaggctgt atttacaatc tcggaacagc aaactgccgg attacagcaa attgcagcag
    13681 cttccggggc gacgctgagc acggtttttc aagcgttgtg gggactgatg ctgcaacgat
    13741 tcaataacag tgacgattct gtgttcggtt ctgtaatttc cggcagacca acggagcttg
    13801 cagacgtgga gggcatggtc gggcttttta tcaatacagt tcccgttcgc atccaaagcg
    13861 gagcgctttc cttctcggat ctggtcaggc atatgcaaaa ggagttactg aaagcagaag
    13921 cttatagtta ttttcctttg tatgatattc aagcgcaaag cgcactcaag caggaactga
    13981 tcgatcatat tatcgtattt gaaaatgtgc cgacacagca ggaaattgag ggattgaacc
    14041 agaccggggc gtttgatttt tcggtggagg acttttcgat ggctgaggaa accaactacg
    14101 ggtgcagtat aaaagtcatt ccgggatcct ctttatatgt acggatcaat tttcatacag
    14161 atttgtatga caccagcatg atggaagaga tcgaagggta tatgcagcaa atgattgcat
    14221 ctgttatcgc tgaccctgat atacgcgctt cacagattcc attgctaaat gaaagcaaaa
    14281 cacggcaaat tgtttctgaa ttcaacaaaa cagaagctgt ttcacctata gctccgactc
    14341 tccacggcct gtttacacgc caggcggcgc ttacgccgga tcggccggcg attcacttcg
    14401 ctaatgggag cctgacatac ggggagcttg atgcgtattc aaacaggctg gccgtgcgcc
    14461 ttgcggcgaa aggcgtgacg aaagaaagca ttgtcggcat ccttgccgag cgctcgccgg
    14521 aaatgatgat tgccgtgctg gccgttttga aagcgggcgg cgcttatctg ccgcttgatc
    14581 cggcgtatcc tgacgggcgc ctgagctaca tgctgaaaga cagcggggcg gcgcttatgc
    14641 tgacacagtc tggtttaacg gttcccgatt tttcaggtga gacgcttgaa gtggatatgg
    14701 aggcgcctgt ggatggcaat ccttcagaag tgcctgcagg cacagccgac agcggctctc
    14761 tggcgtatct catttatacc tccggctcca cggggcagcc aaagggcgtg gcggtggagc
    14821 atcgccaggc ggtttctttt ctgaccggca tgcaacggca gtttccgtta cataagaagg
    14881 atgtcattgt gctgaaaacg tcattttcat ttgacgcgtc tgtctggcag ttgttctggt
    14941 ggacactctc aggcgcttcg acctatctgc ttccgtctgg ct
//
