LOCUS       NZ_JALATJ010000012     14995 bp    DNA     linear   CON 26-JAN-2024
DEFINITION  Bacillus inaquosorum strain WR203A-1m Contig_0000012, whole genome
            shotgun sequence.
ACCESSION   NZ_JALATJ010000012
VERSION     NZ_JALATJ010000012.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus inaquosorum
  ORGANISM  Bacillus inaquosorum
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 14995)
  AUTHORS   Dunlap,C.
  TITLE     Crop Bioprotection Bacillus Genome Sequencing
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 14995)
  AUTHORS   Dunlap,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-FEB-2022) CBP, USDA-ARS-NCAUR, 1815 N. University St.,
            Peoria, IL 61604, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC NGS Cell v. 21
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 488.8726095687877x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/24/2024 02:44:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,221
            CDSs (total)                      :: 4,141
            Genes (coding)                    :: 4,013
            CDSs (with protein)               :: 4,013
            Genes (RNA)                       :: 80
            rRNAs                             :: 5, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 80 of 128
            Pseudo Genes (incomplete)         :: 71 of 128
            Pseudo Genes (internal stop)      :: 24 of 128
            Pseudo Genes (multiple problems)  :: 38 of 128
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:31:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 14995
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JALATJ010000012.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..14995
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     gene            <1..3794
                     /locus_tag="MOD90_RS21060"
                     /old_locus_tag="MOD90_21010"
     source          1..14995
                     /db_xref="taxon:483913"
                     /isolation_source="soil"
                     /mol_type="genomic DNA"
                     /organism="Bacillus inaquosorum"
                     /strain="WR203A-1m"
                     /submitter_seqid="Contig_0000012"
     cand_cluster    1..14995
                     /SMILES="NC(CCCN)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(C(O)C)C(=O)NC
                     (CCC(=O)O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..14995
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<4:>14995](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      <5..>14995
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     CDS             <5..3794
                     /NRPS_PKS="Domain: AMP-binding (205-610). E-value:
                     9.1e-101. Score: 329.3. Matches aSDomain:
                     nrpspksdomains_MOD90_RS21060_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (715-779). E-value: 8.8e-23. Score:
                     72.3. Matches aSDomain: nrpspksdomains_MOD90_RS21060_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (791-1102). E-value:
                     1.5e-144. Score: 474.5. Matches aSDomain:
                     nrpspksdomains_MOD90_RS21060_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (1110-1255). E-value: 6e-46.
                     Score: 148.0. Matches aSDomain:
                     nrpspksdomains_MOD90_RS21060_TIGR01720.1"
                     /codon_start=3
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389716.2"
                     /locus_tag="MOD90_RS21060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD90_21010"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_268281232.1"
                     /sec_met_domain="AMP-binding (E-value: 1.5e-110, bitscore:
                     357.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.4e-17, bitscore:
                     51.8, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 3.9e-87, bitscore:
                     279.7, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="RLSGHEDIIVGSPIVGRPHKDLEPILGMFVNTLALRTRPEGGKPF
                     VQYLQEVRETALEAYEHQDYPFEELVDKLELTRDMSRNPVFDAMFILQNMEKQDMDLEE
                     VKVRPANFAHHISLFDITLIATETDGAICCELEFSTEVFLKATIERWAAHFIEFLHAAL
                     SNPETNLSQINILSDKEKQNIVFEFNKTQVEFSQKDVPFHRIFEARAEETPEHIAVIDD
                     ETQISYRLLNERANRLARTLQKRKGTKPTVAVLAKRSIDAIVGILAVMKAGGVYIPIDS
                     HYPKARIEYLLRDSEADILLLQQELKHLISNSSECDISHICLDDESSYEENSCNLDLSP
                     APEDVAYIIYTSGTTGAPKGVIVTYRNFTHAALAWRQIYELDQKPVRLLQMASFSFDVF
                     SGDLARTLINGGTLIVCPDEKRLEPAELYGIMNSRRITIMESTPALIIPIMEYVYRNKL
                     KLPDLDILILGSDMVKAQDFKTLTERFGQSMRIINSYGVTEATIDSSCYETRMGEEYTG
                     DNVPIGSPLPNVHMYVLSQTNQIQPIGVAGELCISGAGVAKGYHNKPDLTQMKFTENPF
                     VSGERLYRTGDRACWLPNGTITLLGRMDYQVKINGYRIETEEIESVLLQTGLVREAAVA
                     VQHDKNGHAGLAAYIVPSDVNTNTLRAALTKELPAYMIPAHLIPIEKLPLTLNGKLDKN
                     ALPAPNDVFTRPYTAPVNDIQKTIAEIWEDVLSIARVGIHDSFFELGGDSIKALQVAAR
                     LAAEGWSMTIRDLFRYPTIQELSGHITPLASQADQGPAEGEADLAPIQRRFFGQVHAFH
                     YHYNQSVILFSEKGFNTNALRRALRKITEHHDAIRMVFQRHQNGHVVQYNRGMNHNDHE
                     LFGLHIADWTKESLERTQFDEKLAAEEIGIQSKMNVQKGPLLQAGLFKTAEGDHLLIAL
                     HHLVIDGVSWRILLEDLAAAYQQALEKQEIQLPPKTDSYLSYANGLAQIAENKQLLAEK
                     SYWQSILDAHTAFLPKDTENVPGRLQMNSDTAAFVLSGDWTEKLLFETQQAYGTNANEL
                     LLTALGMALSEWTGHDQIVISTEGHGREGHVPNIDISRTVGWFTSIYPILLDMGIPEPF
                     EDQLAYRIKTTKDMLRRVPNKGTGYGLLTHIGELPHKEPEVSFNYLGQFSEEKEAETFQ
                     LSYYQPRYEIAGEREREYELDINALITDGRLQVKAVYTQVFNQHSIECFMDRFHRHLIE
                     MIEHCSQKKIREKTLSDFSNKELTLSALSSIEDLVKDL"
     CDS_motif       24..113
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21060_0001"
                     /evalue="1.70E-14"
                     /label="C5_LCL_267-296"
                     /locus_tag="MOD90_RS21060"
                     /protein_end="36"
                     /protein_start="6"
                     /score="46.1"
                     /tool="antismash"
                     /translation="DIIVGSPIVGRPHKDLEPILGMFVNTLALR"
     CDS_motif       162..281
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21060_0002"
                     /evalue="2.20E-21"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="MOD90_RS21060"
                     /protein_end="92"
                     /protein_start="52"
                     /score="68.3"
                     /tool="antismash"
                     /translation="RETALEAYEHQDYPFEELVDKLELTRDMSRNPVFDAMFIL"
     aSDomain        621..1835
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOD90_RS21060_AMP-binding.1"
                     /evalue="9.10E-101"
                     /label="MOD90_RS21060_AMP-binding.1"
                     /locus_tag="MOD90_RS21060"
                     /protein_end="610"
                     /protein_start="205"
                     /score="329.3"
                     /specificity="substrate consensus: Orn"
                     /tool="antismash"
                     /translation="FEARAEETPEHIAVIDDETQISYRLLNERANRLARTLQKRKGTKP
                     TVAVLAKRSIDAIVGILAVMKAGGVYIPIDSHYPKARIEYLLRDSEADILLLQQELKHL
                     ISNSSECDISHICLDDESSYEENSCNLDLSPAPEDVAYIIYTSGTTGAPKGVIVTYRNF
                     THAALAWRQIYELDQKPVRLLQMASFSFDVFSGDLARTLINGGTLIVCPDEKRLEPAEL
                     YGIMNSRRITIMESTPALIIPIMEYVYRNKLKLPDLDILILGSDMVKAQDFKTLTERFG
                     QSMRIINSYGVTEATIDSSCYETRMGEEYTGDNVPIGSPLPNVHMYVLSQTNQIQPIGV
                     AGELCISGAGVAKGYHNKPDLTQMKFTENPFVSGERLYRTGDRACWLPNGTITLLGRMD
                     YQVKIN"
     aSModule        621..3770
                     /complete
                     /domains="nrpspksdomains_MOD90_RS21060_AMP-binding.1"
                     /domains="nrpspksdomains_MOD90_RS21060_PCP.1"
                     /domains="nrpspksdomains_MOD90_RS21060_Epimerization.1"
                     /domains="nrpspksdomains_MOD90_RS21060_TIGR01720.1"
                     /locus_tags="MOD90_RS21060"
                     /monomer_pairings="Orn -> D-Orn"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       804..845
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21060_0003"
                     /evalue="7.50E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="MOD90_RS21060"
                     /protein_end="280"
                     /protein_start="266"
                     /score="16.0"
                     /tool="antismash"
                     /translation="LAVMKAGGVYIPID"
     CDS_motif       1041..1097
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21060_0004"
                     /evalue="2.50E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="MOD90_RS21060"
                     /protein_end="364"
                     /protein_start="345"
                     /score="26.1"
                     /tool="antismash"
                     /translation="AYIIYTSGTTGAPKGVIVT"
     CDS_motif       1629..1718
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21060_0005"
                     /evalue="8.60E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="MOD90_RS21060"
                     /protein_end="571"
                     /protein_start="541"
                     /score="46.8"
                     /tool="antismash"
                     /translation="PIGVAGELCISGAGVAKGYHNKPDLTQMKF"
     CDS_motif       1803..1865
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21060_0006"
                     /evalue="2.50E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="MOD90_RS21060"
                     /protein_end="620"
                     /protein_start="599"
                     /score="29.3"
                     /tool="antismash"
                     /translation="LGRMDYQVKINGYRIETEEIE"
     CDS_motif       1962..2093
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21060_0007"
                     /evalue="6.00E+00"
                     /label="C2_LCL_024-062"
                     /locus_tag="MOD90_RS21060"
                     /protein_end="696"
                     /protein_start="652"
                     /score="-0.6"
                     /tool="antismash"
                     /translation="SDVNTNTLRAALTKELPAYMIPAHLIPIEKLPLTLNGKLDKNAL"
     aSDomain        2151..2342
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOD90_RS21060_PCP.1"
                     /evalue="8.80E-23"
                     /label="MOD90_RS21060_PCP.1"
                     /locus_tag="MOD90_RS21060"
                     /protein_end="779"
                     /protein_start="715"
                     /score="72.3"
                     /tool="antismash"
                     /translation="KTIAEIWEDVLSIARVGIHDSFFELGGDSIKALQVAARLAAEGWS
                     MTIRDLFRYPTIQELSGHI"
     aSDomain        2379..3311
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOD90_RS21060_Epimerization.1"
                     /evalue="1.50E-144"
                     /label="MOD90_RS21060_Epimerization.1"
                     /locus_tag="MOD90_RS21060"
                     /protein_end="1102"
                     /protein_start="791"
                     /score="474.5"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLVIDG"
                     /tool="antismash"
                     /translation="EGEADLAPIQRRFFGQVHAFHYHYNQSVILFSEKGFNTNALRRAL
                     RKITEHHDAIRMVFQRHQNGHVVQYNRGMNHNDHELFGLHIADWTKESLERTQFDEKLA
                     AEEIGIQSKMNVQKGPLLQAGLFKTAEGDHLLIALHHLVIDGVSWRILLEDLAAAYQQA
                     LEKQEIQLPPKTDSYLSYANGLAQIAENKQLLAEKSYWQSILDAHTAFLPKDTENVPGR
                     LQMNSDTAAFVLSGDWTEKLLFETQQAYGTNANELLLTALGMALSEWTGHDQIVISTEG
                     HGREGHVPNIDISRTVGWFTSIYPILLDMG"
     CDS_motif       2484..2555
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21060_0008"
                     /evalue="1.40E-04"
                     /label="C2_LCL_024-062"
                     /locus_tag="MOD90_RS21060"
                     /protein_end="850"
                     /protein_start="826"
                     /score="14.3"
                     /tool="antismash"
                     /translation="FNTNALRRALRKITEHHDAIRMVF"
     CDS_motif       2781..2846
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21060_0009"
                     /evalue="2.60E-11"
                     /label="NRPS-E2"
                     /locus_tag="MOD90_RS21060"
                     /protein_end="947"
                     /protein_start="925"
                     /score="35.7"
                     /tool="antismash"
                     /translation="LLIALHHLVIDGVSWRILLEDL"
     CDS_motif       3252..3302
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21060_0010"
                     /evalue="4.50E-09"
                     /label="NRPS-E5"
                     /locus_tag="MOD90_RS21060"
                     /protein_end="1099"
                     /protein_start="1082"
                     /score="28.2"
                     /tool="antismash"
                     /translation="DISRTVGWFTSIYPILL"
     aSDomain        3336..3770
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOD90_RS21060_TIGR01720.1"
                     /evalue="6.00E-46"
                     /label="MOD90_RS21060_TIGR01720.1"
                     /locus_tag="MOD90_RS21060"
                     /protein_end="1255"
                     /protein_start="1110"
                     /score="148.0"
                     /tool="antismash"
                     /translation="LAYRIKTTKDMLRRVPNKGTGYGLLTHIGELPHKEPEVSFNYLGQ
                     FSEEKEAETFQLSYYQPRYEIAGEREREYELDINALITDGRLQVKAVYTQVFNQHSIEC
                     FMDRFHRHLIEMIEHCSQKKIREKTLSDFSNKELTLSALSS"
     CDS_motif       3357..3416
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21060_0011"
                     /evalue="9.40E-09"
                     /label="NRPS-E6"
                     /locus_tag="MOD90_RS21060"
                     /protein_end="1137"
                     /protein_start="1117"
                     /score="27.5"
                     /tool="antismash"
                     /translation="TKDMLRRVPNKGTGYGLLTH"
     aSDomain        3819..3902
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOD90_RS21065_NRPS-COM_Nterm.1"
                     /evalue="7.40E-16"
                     /label="MOD90_RS21065_NRPS-COM_Nterm.1"
                     /locus_tag="MOD90_RS21065"
                     /protein_end="28"
                     /protein_start="0"
                     /score="49.1"
                     /tool="antismash"
                     /translation="MAQAAQIQDIYPLSHMQEGMLFHSLMDV"
     gene            3819..11501
                     /locus_tag="MOD90_RS21065"
                     /old_locus_tag="MOD90_21015"
     CDS             3819..11501
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (0-28). E-value: 7.4e-16.
                     Score: 49.1. Matches aSDomain:
                     nrpspksdomains_MOD90_RS21065_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (7-309). E-value:
                     3e-110. Score: 360.0. Matches aSDomain:
                     nrpspksdomains_MOD90_RS21065_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (474-865). E-value:
                     2.5e-110. Score: 360.8. Matches aSDomain:
                     nrpspksdomains_MOD90_RS21065_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (970-1036). E-value: 3e-22. Score:
                     70.6. Matches aSDomain: nrpspksdomains_MOD90_RS21065_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1054-1341). E-value:
                     3.3e-105. Score: 343.3. Matches aSDomain:
                     nrpspksdomains_MOD90_RS21065_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1505-1903). E-value:
                     4.8e-118. Score: 386.2. Matches aSDomain:
                     nrpspksdomains_MOD90_RS21065_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2011-2078). E-value: 1.9e-20.
                     Score: 64.8. Matches aSDomain:
                     nrpspksdomains_MOD90_RS21065_PCP.2"
                     /NRPS_PKS="Domain: Epimerization (2088-2393). E-value:
                     1.4e-149. Score: 491.2. Matches aSDomain:
                     nrpspksdomains_MOD90_RS21065_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (2403-2553). E-value: 2.2e-52.
                     Score: 168.9. Matches aSDomain:
                     nrpspksdomains_MOD90_RS21065_TIGR01720.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389715.1"
                     /locus_tag="MOD90_RS21065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD90_21015"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_268281233.1"
                     /sec_met_domain="Condensation (E-value: 6.3e-95, bitscore:
                     305.3, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.1e-126, bitscore:
                     410.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.2e-16, bitscore:
                     48.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQAAQIQDIYPLSHMQEGMLFHSLMDVSSKAYVEQTSFTITGNL
                     CIDSFQKSLNLLVSRYDIFRTIFIKEVQDLTGPQQVVLSNRELTVYREDFSHLADHEQQ
                     ALIDAFMTKDREKGFNLQKDPLMRLALFDRGNSQYTCVWTHHHIIMDGWCLGIILKEFF
                     SMYDSLKNNSPVRLGSTVPYSRYIEWLGEQDQEETAAYWSEYLKEYGNTASIPRINPRP
                     ADGDYKADQISFSLAPEMVEKLTEAAQNWGVTLNTLFMSMWGVLLHRYNAADDAVFGSV
                     ISGRPSAIDGIESMVGLFINTIPVRIRSAEGMTFSSLAKAVQEDILASEQHGYYPLYEI
                     QNHSPLKQGLIDHIFVFENYPVQLDQALSIESEDEENALKLGDISMSEQTNYDFNIVIV
                     PGESFYIKFSYNAAVYEREEMLRIQGHLKQALDCILAHPDIAVSDINIVPPEEQQVIQL
                     FNETERPYVNKTISQLFEEQARKTPEAAALKLGDDCWTYRQLNIRANQIAHALIEKGVG
                     SGDIVAVMMNRSMEMPAALLGIWKAGGAYMPLDPNFPEERLSFLLKDSQAAQLLIEENL
                     MSFIPPHYKGNMITIERTESYQSAAPDVPLGDLAYLIYTSGTTGRPKGVLVNHQGIANT
                     LQWRREEYGMTEQDISLHLFSYVFDGCVTSLFTPLLSGACVLLTTDDEAKDVLALKRKI
                     ARYKVSHMIIVPSLYRVLLEVMTADDAKSLRIVTFAGEAVTPDLLEMSEKICPFAELAN
                     EYGPTENSVATTILRQLNEKERITIGHPIANTKVFVLHGNQMQPIGAAGELCISGEGLA
                     KGYYKQPELTDKAFSDHPFLEGERLYRTGDAGRFLPDGTIEYIGRFDDQVKIRGYRIEL
                     KEIETVLRQAPGVKEAAVLARDVSAEEKELVAYIVPEKGNNLPNLYWHLAGTLPPYMIP
                     ATIINISRMPLTSSGKLDRSALPEPENNASLTYMPPRTLIEADLAHIWGDVLNKQQIGI
                     RDDFFQLGGQSLKAAALVSRIHKKLNIELPISEVFSNPTVESMAVKLMSLKEHAFTQIE
                     PADQRDVYPLSFSQKRLYALHQLADDSTGYNMPAVLELRGNLDRQRLRSVLTELVNRHE
                     VLRTVFVFDRGEPVQIIHPEMAFDLKELEMESEQMLESAIESFIKPFDLSSGPLFRACV
                     ITMGNNRGFLLLDMHHIIADGVSMSTLVQEFTDLYCEKELPALNLHYKDFAVWQQEKYP
                     KELYKKQEAYWLDQLGGSLPVLELPLDKTRPRLPDFSGGTIEVNIDKDTADELHRLMVE
                     TGTTLYMILLAVYSILLSKLSRQEDIVVGSPAAGRPHADLERVIGMFVNTLAMRSQPEG
                     HKTFSSYLQDIRHLALTAYEHQDYPFEELADKLDTHREVNRNPLFDAMLVLQSSEDFQF
                     EVPGLSISSVTPKHDISKFDLTLHAEEHSSGIHCRFEYSTALFEEETIARWASHFIELV
                     KSVTADTEMRISEMQLLPAAERNLLLEKMGQYAAYPRNENIVSLFEKQAAEHPEHLAVV
                     YGHSQLTYRDLNEKAERTAAMLIKQGVRTGDIVGLMLDRSPAMIIGILSILKAGGAYLP
                     IDPEYPQERISFMLNDSGAKMLLTERGQNNPADYNGPIMYIDEGDSDSIPDDLNIQEIL
                     SDQPAYVIYTSGTTGQPKGVIVEHRNVISLLKHQNLPFEFGHEDVWTLFHSYCFDFSVW
                     EMFGALLNGSTLVVVSKETARDPHAFRLLLKKERVTVLNQTPTAFYSLMHEDQNHPDRL
                     NIRYVIFGGEALQPGMLQSWNEKYPDTDLINMYGITETTVHVTFKKLSAADIAKKKSNI
                     GRPLSTLQAYVMDAHMNLQPIGVPGEMYIGGEGVARGYLNRDELTADRFVPNPYLPGDR
                     LYRTGDLAKRLSNGELEYLGRIDDQVKVRGHRIELGEIQAALLQLPAIKEAAVITRTDE
                     QGQAAVYAYIVTKDQQAANASEIRTSLKTMLPDFMLPARLIQIDSIPLTVNGKLDQKAL
                     PEPDKHDYIADDIRPRNEIEKVMAEIWEELLDVEELGVSANFFELGGDSIKALQVCARL
                     KQCGFETTVREMFEHQTLGELSARVRKAVHVIDQGPVEGEITWTPIQQWFFSQSLEIHH
                     FNQSVMLYRTERFDETALKKVLKSLVIHHDALRIVCRYENGRPVQISRGIDLPDKELYA
                     LELFDIKDNLTEAHNRIKEAASQMQEHMRLETGPLLHAGLFRTENGDHLFLTIHHLVVD
                     AVSWRILFEDFSTAYKQAVSGESIKLPQKTDSYLTYSQRIADYSKSRQIQREEAYWDER
                     ENRYIQPIPKDNDAAHNIFKDTEVIDFELSRHHTELLLTAAHKAYSTEMNDILLTALGL
                     ALQQWTGYDQFKISMEGHGRESYLEDIDISRTVGWFTSIYPVWLDMSHSDHKNKDERLG
                     HLIKQTKDMLHRIPHKGAGYGVLKYTNKKWGSEKGSPDISFNYLGQFDQDIQSKAFEVS
                     DIKPGNEISPEWERPYALDISGAVSSGCLNMHMIYNRLQFEKKTIQTFAEHFKQTLENI
                     IEHCTGKENREWSASDFTDEDLTLDELSEIMGAVNKL"
     aSDomain        3840..4745
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOD90_RS21065_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="3.00E-110"
                     /label="MOD90_RS21065_Condensation_DCL.1"
                     /locus_tag="MOD90_RS21065"
                     /protein_end="309"
                     /protein_start="7"
                     /score="360.0"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIIMDG"
                     /tool="antismash"
                     /translation="QDIYPLSHMQEGMLFHSLMDVSSKAYVEQTSFTITGNLCIDSFQK
                     SLNLLVSRYDIFRTIFIKEVQDLTGPQQVVLSNRELTVYREDFSHLADHEQQALIDAFM
                     TKDREKGFNLQKDPLMRLALFDRGNSQYTCVWTHHHIIMDGWCLGIILKEFFSMYDSLK
                     NNSPVRLGSTVPYSRYIEWLGEQDQEETAAYWSEYLKEYGNTASIPRINPRPADGDYKA
                     DQISFSLAPEMVEKLTEAAQNWGVTLNTLFMSMWGVLLHRYNAADDAVFGSVISGRPSA
                     IDGIESMVGLFINTIPVRIRS"
     aSModule        3840..6926
                     /complete
                     /domains="nrpspksdomains_MOD90_RS21065_Condensation_DCL.1"
                     /domains="nrpspksdomains_MOD90_RS21065_AMP-binding.1"
                     /domains="nrpspksdomains_MOD90_RS21065_PCP.1"
                     /locus_tags="MOD90_RS21065"
                     /monomer_pairings="Tyr -> Tyr"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       3849..3890
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21065_0001"
                     /evalue="9.00E-05"
                     /label="C1_DCL_004-017"
                     /locus_tag="MOD90_RS21065"
                     /protein_end="24"
                     /protein_start="10"
                     /score="14.5"
                     /tool="antismash"
                     /translation="YPLSHMQEGMLFHS"
     CDS_motif       3912..4025
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21065_0002"
                     /evalue="1.70E-14"
                     /label="C2_DCL_024-062"
                     /locus_tag="MOD90_RS21065"
                     /protein_end="69"
                     /protein_start="31"
                     /score="46.1"
                     /tool="antismash"
                     /translation="AYVEQTSFTITGNLCIDSFQKSLNLLVSRYDIFRTIFI"
     CDS_motif       4251..4316
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21065_0003"
                     /evalue="2.50E-11"
                     /label="C3_DCL_135-156"
                     /locus_tag="MOD90_RS21065"
                     /protein_end="166"
                     /protein_start="144"
                     /score="35.9"
                     /tool="antismash"
                     /translation="HHHIIMDGWCLGIILKEFFSMY"
     CDS_motif       4641..4736
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21065_0004"
                     /evalue="4.20E-19"
                     /label="C5_DCL_263-294"
                     /locus_tag="MOD90_RS21065"
                     /protein_end="306"
                     /protein_start="274"
                     /score="61.0"
                     /tool="antismash"
                     /translation="DAVFGSVISGRPSAIDGIESMVGLFINTIPVR"
     CDS_motif       4785..4901
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21065_0005"
                     /evalue="6.20E-20"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="MOD90_RS21065"
                     /protein_end="361"
                     /protein_start="322"
                     /score="63.7"
                     /tool="antismash"
                     /translation="QEDILASEQHGYYPLYEIQNHSPLKQGLIDHIFVFENYP"
     aSDomain        5241..6413
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOD90_RS21065_AMP-binding.1"
                     /evalue="2.50E-110"
                     /label="MOD90_RS21065_AMP-binding.1"
                     /locus_tag="MOD90_RS21065"
                     /protein_end="865"
                     /protein_start="474"
                     /score="360.8"
                     /specificity="substrate consensus: Tyr"
                     /tool="antismash"
                     /translation="FEEQARKTPEAAALKLGDDCWTYRQLNIRANQIAHALIEKGVGSG
                     DIVAVMMNRSMEMPAALLGIWKAGGAYMPLDPNFPEERLSFLLKDSQAAQLLIEENLMS
                     FIPPHYKGNMITIERTESYQSAAPDVPLGDLAYLIYTSGTTGRPKGVLVNHQGIANTLQ
                     WRREEYGMTEQDISLHLFSYVFDGCVTSLFTPLLSGACVLLTTDDEAKDVLALKRKIAR
                     YKVSHMIIVPSLYRVLLEVMTADDAKSLRIVTFAGEAVTPDLLEMSEKICPFAELANEY
                     GPTENSVATTILRQLNEKERITIGHPIANTKVFVLHGNQMQPIGAAGELCISGEGLAKG
                     YYKQPELTDKAFSDHPFLEGERLYRTGDAGRFLPDGTIEYIGRFDDQVKIR"
     CDS_motif       5427..5468
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21065_0006"
                     /evalue="6.80E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="MOD90_RS21065"
                     /protein_end="550"
                     /protein_start="536"
                     /score="16.1"
                     /tool="antismash"
                     /translation="LGIWKAGGAYMPLD"
     CDS_motif       5646..5705
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21065_0007"
                     /evalue="2.20E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="MOD90_RS21065"
                     /protein_end="629"
                     /protein_start="609"
                     /score="29.3"
                     /tool="antismash"
                     /translation="AYLIYTSGTTGRPKGVLVNH"
     CDS_motif       6078..6110
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21065_0008"
                     /evalue="1.20E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="MOD90_RS21065"
                     /protein_end="764"
                     /protein_start="753"
                     /score="5.7"
                     /tool="antismash"
                     /translation="EYGPTENSVAT"
     CDS_motif       6207..6296
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21065_0009"
                     /evalue="1.10E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="MOD90_RS21065"
                     /protein_end="826"
                     /protein_start="796"
                     /score="43.3"
                     /tool="antismash"
                     /translation="PIGAAGELCISGEGLAKGYYKQPELTDKAF"
     CDS_motif       6378..6443
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21065_0010"
                     /evalue="2.70E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="MOD90_RS21065"
                     /protein_end="875"
                     /protein_start="853"
                     /score="35.4"
                     /tool="antismash"
                     /translation="YIGRFDDQVKIRGYRIELKEIE"
     aSDomain        6729..6926
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOD90_RS21065_PCP.1"
                     /evalue="3.00E-22"
                     /label="MOD90_RS21065_PCP.1"
                     /locus_tag="MOD90_RS21065"
                     /protein_end="1036"
                     /protein_start="970"
                     /score="70.6"
                     /tool="antismash"
                     /translation="EADLAHIWGDVLNKQQIGIRDDFFQLGGQSLKAAALVSRIHKKLN
                     IELPISEVFSNPTVESMAVKL"
     aSDomain        6981..7841
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOD90_RS21065_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="3.30E-105"
                     /label="MOD90_RS21065_Condensation_LCL.1"
                     /locus_tag="MOD90_RS21065"
                     /protein_end="1341"
                     /protein_start="1054"
                     /score="343.3"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIIADG"
                     /tool="antismash"
                     /translation="VYPLSFSQKRLYALHQLADDSTGYNMPAVLELRGNLDRQRLRSVL
                     TELVNRHEVLRTVFVFDRGEPVQIIHPEMAFDLKELEMESEQMLESAIESFIKPFDLSS
                     GPLFRACVITMGNNRGFLLLDMHHIIADGVSMSTLVQEFTDLYCEKELPALNLHYKDFA
                     VWQQEKYPKELYKKQEAYWLDQLGGSLPVLELPLDKTRPRLPDFSGGTIEVNIDKDTAD
                     ELHRLMVETGTTLYMILLAVYSILLSKLSRQEDIVVGSPAAGRPHADLERVIGMFVNTL
                     AMRSQP"
     aSModule        6981..11477
                     /complete
                     /domains="nrpspksdomains_MOD90_RS21065_Condensation_LCL.1"
                     /domains="nrpspksdomains_MOD90_RS21065_AMP-binding.2"
                     /domains="nrpspksdomains_MOD90_RS21065_PCP.2"
                     /domains="nrpspksdomains_MOD90_RS21065_Epimerization.1"
                     /domains="nrpspksdomains_MOD90_RS21065_TIGR01720.1"
                     /locus_tags="MOD90_RS21065"
                     /monomer_pairings="Thr -> D-Thr"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       7050..7160
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21065_0011"
                     /evalue="2.50E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="MOD90_RS21065"
                     /protein_end="1114"
                     /protein_start="1077"
                     /score="55.3"
                     /tool="antismash"
                     /translation="YNMPAVLELRGNLDRQRLRSVLTELVNRHEVLRTVFV"
     CDS_motif       7356..7421
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21065_0012"
                     /evalue="1.90E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="MOD90_RS21065"
                     /protein_end="1201"
                     /protein_start="1179"
                     /score="30.0"
                     /tool="antismash"
                     /translation="MHHIIADGVSMSTLVQEFTDLY"
     CDS_motif       7452..7487
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21065_0013"
                     /evalue="5.60E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="MOD90_RS21065"
                     /protein_end="1223"
                     /protein_start="1211"
                     /score="12.6"
                     /tool="antismash"
                     /translation="HYKDFAVWQQEK"
     CDS_motif       7743..7832
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21065_0014"
                     /evalue="8.90E-17"
                     /label="C5_LCL_267-296"
                     /locus_tag="MOD90_RS21065"
                     /protein_end="1338"
                     /protein_start="1308"
                     /score="53.4"
                     /tool="antismash"
                     /translation="DIVVGSPAAGRPHADLERVIGMFVNTLAMR"
     CDS_motif       7887..8000
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21065_0015"
                     /evalue="2.60E-14"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="MOD90_RS21065"
                     /protein_end="1394"
                     /protein_start="1356"
                     /score="45.5"
                     /tool="antismash"
                     /translation="LALTAYEHQDYPFEELADKLDTHREVNRNPLFDAMLVL"
     aSDomain        8334..9527
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOD90_RS21065_AMP-binding.2"
                     /evalue="4.80E-118"
                     /label="MOD90_RS21065_AMP-binding.2"
                     /locus_tag="MOD90_RS21065"
                     /protein_end="1903"
                     /protein_start="1505"
                     /score="386.2"
                     /specificity="substrate consensus: Thr"
                     /tool="antismash"
                     /translation="FEKQAAEHPEHLAVVYGHSQLTYRDLNEKAERTAAMLIKQGVRTG
                     DIVGLMLDRSPAMIIGILSILKAGGAYLPIDPEYPQERISFMLNDSGAKMLLTERGQNN
                     PADYNGPIMYIDEGDSDSIPDDLNIQEILSDQPAYVIYTSGTTGQPKGVIVEHRNVISL
                     LKHQNLPFEFGHEDVWTLFHSYCFDFSVWEMFGALLNGSTLVVVSKETARDPHAFRLLL
                     KKERVTVLNQTPTAFYSLMHEDQNHPDRLNIRYVIFGGEALQPGMLQSWNEKYPDTDLI
                     NMYGITETTVHVTFKKLSAADIAKKKSNIGRPLSTLQAYVMDAHMNLQPIGVPGEMYIG
                     GEGVARGYLNRDELTADRFVPNPYLPGDRLYRTGDLAKRLSNGELEYLGRIDDQVKVR"
     CDS_motif       8520..8561
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21065_0016"
                     /evalue="1.70E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="MOD90_RS21065"
                     /protein_end="1581"
                     /protein_start="1567"
                     /score="15.0"
                     /tool="antismash"
                     /translation="LSILKAGGAYLPID"
     CDS_motif       8745..8804
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21065_0017"
                     /evalue="4.50E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="MOD90_RS21065"
                     /protein_end="1662"
                     /protein_start="1642"
                     /score="31.4"
                     /tool="antismash"
                     /translation="AYVIYTSGTTGQPKGVIVEH"
     CDS_motif       9183..9206
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21065_0018"
                     /evalue="2.50E+00"
                     /label="NRPS-A_a5"
                     /locus_tag="MOD90_RS21065"
                     /protein_end="1796"
                     /protein_start="1788"
                     /score="2.0"
                     /tool="antismash"
                     /translation="YGITETTV"
     CDS_motif       9321..9410
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21065_0019"
                     /evalue="2.30E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="MOD90_RS21065"
                     /protein_end="1864"
                     /protein_start="1834"
                     /score="55.0"
                     /tool="antismash"
                     /translation="PIGVPGEMYIGGEGVARGYLNRDELTADRF"
     CDS_motif       9492..9557
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21065_0020"
                     /evalue="6.90E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="MOD90_RS21065"
                     /protein_end="1913"
                     /protein_start="1891"
                     /score="37.3"
                     /tool="antismash"
                     /translation="YLGRIDDQVKVRGHRIELGEIQ"
     aSDomain        9852..10052
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOD90_RS21065_PCP.2"
                     /evalue="1.90E-20"
                     /label="MOD90_RS21065_PCP.2"
                     /locus_tag="MOD90_RS21065"
                     /protein_end="2078"
                     /protein_start="2011"
                     /score="64.8"
                     /tool="antismash"
                     /translation="EKVMAEIWEELLDVEELGVSANFFELGGDSIKALQVCARLKQCGF
                     ETTVREMFEHQTLGELSARVRK"
     aSDomain        10083..10997
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOD90_RS21065_Epimerization.1"
                     /evalue="1.40E-149"
                     /label="MOD90_RS21065_Epimerization.1"
                     /locus_tag="MOD90_RS21065"
                     /protein_end="2393"
                     /protein_start="2088"
                     /score="491.2"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLVVDA"
                     /tool="antismash"
                     /translation="EGEITWTPIQQWFFSQSLEIHHFNQSVMLYRTERFDETALKKVLK
                     SLVIHHDALRIVCRYENGRPVQISRGIDLPDKELYALELFDIKDNLTEAHNRIKEAASQ
                     MQEHMRLETGPLLHAGLFRTENGDHLFLTIHHLVVDAVSWRILFEDFSTAYKQAVSGES
                     IKLPQKTDSYLTYSQRIADYSKSRQIQREEAYWDERENRYIQPIPKDNDAAHNIFKDTE
                     VIDFELSRHHTELLLTAAHKAYSTEMNDILLTALGLALQQWTGYDQFKISMEGHGRESY
                     LEDIDISRTVGWFTSIYPVWLDMS"
     CDS_motif       10098..10124
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21065_0021"
                     /evalue="2.90E-03"
                     /label="NRPS-E1"
                     /locus_tag="MOD90_RS21065"
                     /protein_end="2102"
                     /protein_start="2093"
                     /score="10.8"
                     /tool="antismash"
                     /translation="WTPIQQWFF"
     CDS_motif       10182..10247
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21065_0022"
                     /evalue="4.90E-02"
                     /label="C2_LCL_024-062"
                     /locus_tag="MOD90_RS21065"
                     /protein_end="2143"
                     /protein_start="2121"
                     /score="6.1"
                     /tool="antismash"
                     /translation="RFDETALKKVLKSLVIHHDALR"
     CDS_motif       10470..10535
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21065_0023"
                     /evalue="1.60E-11"
                     /label="NRPS-E2"
                     /locus_tag="MOD90_RS21065"
                     /protein_end="2239"
                     /protein_start="2217"
                     /score="36.3"
                     /tool="antismash"
                     /translation="LFLTIHHLVVDAVSWRILFEDF"
     CDS_motif       10938..10988
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21065_0024"
                     /evalue="5.10E-09"
                     /label="NRPS-E5"
                     /locus_tag="MOD90_RS21065"
                     /protein_end="2390"
                     /protein_start="2373"
                     /score="28.0"
                     /tool="antismash"
                     /translation="DISRTVGWFTSIYPVWL"
     aSDomain        11028..11477
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOD90_RS21065_TIGR01720.1"
                     /evalue="2.20E-52"
                     /label="MOD90_RS21065_TIGR01720.1"
                     /locus_tag="MOD90_RS21065"
                     /protein_end="2553"
                     /protein_start="2403"
                     /score="168.9"
                     /tool="antismash"
                     /translation="LGHLIKQTKDMLHRIPHKGAGYGVLKYTNKKWGSEKGSPDISFNY
                     LGQFDQDIQSKAFEVSDIKPGNEISPEWERPYALDISGAVSSGCLNMHMIYNRLQFEKK
                     TIQTFAEHFKQTLENIIEHCTGKENREWSASDFTDEDLTLDELSEI"
     CDS_motif       11049..11108
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21065_0025"
                     /evalue="5.20E-08"
                     /label="NRPS-E6"
                     /locus_tag="MOD90_RS21065"
                     /protein_end="2430"
                     /protein_start="2410"
                     /score="25.2"
                     /tool="antismash"
                     /translation="TKDMLHRIPHKGAGYGVLKY"
     gene            11521..>14995
                     /locus_tag="MOD90_RS21070"
                     /old_locus_tag="MOD90_21020"
     CDS             11521..>14995
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (2-30). E-value: 2.8e-16.
                     Score: 50.4. Matches aSDomain:
                     nrpspksdomains_MOD90_RS21070_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (7-305). E-value:
                     1.5e-117. Score: 383.9. Matches aSDomain:
                     nrpspksdomains_MOD90_RS21070_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (469-870). E-value:
                     1.3e-111. Score: 365.1. Matches aSDomain:
                     nrpspksdomains_MOD90_RS21070_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (972-1041). E-value: 2.3e-26. Score:
                     83.8. Matches aSDomain: nrpspksdomains_MOD90_RS21070_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389714.1"
                     /locus_tag="MOD90_RS21070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD90_21020"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_268281234.1"
                     /sec_met_domain="Condensation (E-value: 1.7e-93, bitscore:
                     300.6, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 6e-122, bitscore:
                     394.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.3e-17, bitscore:
                     51.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQQPEIQDIYPLSFMQEGMLFHSLYDEQSRAYFEQASFTIHGQL
                     DLERFQKSMDAVFERYEIFRTAFIYKNVAKPRQVVLKHRHCHVHFEDISHLNERDKEHC
                     TEAFKEQDKSRGFDLQTDVLMRISILKWAPDRYVCIWSHHHILMDGWCLGIVIKDFLHI
                     YQALGKGQLPDLHPVQPYGTYIKWLMQQDREEAAEYWKKRLQHFEKATPLPKRTDQIPD
                     GTLEQITFTISEKETSELQKIAAASGATLNTVFQALWGIMLQKFNRCGDAVFGSVISGR
                     PSELRDVENMVGLFINTIPIRVQSDSLSFSNLVSRMQKDMTEAEAYSYFPLYDIQAQSA
                     LKQELIDHIIVFENTPTQQEIEGLNQAGSFDFSVKDFEMEEVTNYSCSVKVIPGRTLYV
                     RIHFHTGAYQPSMMSEIKDYLQHMVSDVISDPSLPVSKMTLLDENKTRKIVSQNNGAVS
                     VSPEAPTLHGLFERQAAVTPERPAIRFSGGSLTYAELDMYAGRLAARLAARGVTKESIV
                     GVLSERSPEMLIAVLAVLKAGGAYLPLDPAYPKERLSYMLKDSGAAFLLVQPGCSAPSF
                     SGEMLEVDMASLASEKAENDVFTPADGGSLAYVIYTSGSTGKPKGVAVEHRQAVSFLTG
                     MQRQSPLQEDDIVMVKTSFSFDASVWQLFWWSLSGASAYLLPPGWEKDPALIVQAIHQE
                     SITTAHFIPAMLNSFLDQAEMKALGDGTSLKRVFAGGESLAPHVAARFASLLPQVSLIH
                     GYGPTEATVDAAFYVLDPERDRDRLRIPIGKPVPGARLYVLDPHLAVQPCGVAGELYIA
                     GSGVARGYLNRPALTEERFLEDPFYPGERMYKTGDLARWLPDGHVEFLGRLDDQVKIRG
                     YRIEPGEIEAVLRGIEGIREAAVTVRTDSGEPELCAYTEGFGRNEVRAQLETLLPGYMI
                     PAHMIEMEQWPVTPSGKLDRNALPAPDGAADEETYTAPRNVTEMKLAQLWEDVLKNGPV
                     GIHDNFFDRGGHSLKATALVSRIAKEFDVQVPLKDVFAHPTVEGLASVIREGTDSPYEA
                     MKPAEKREAYPVSSAQKRIYVLQQLEDGGTGYNMPAVLELEGKLDPERLDRAFKELIKR
                     HESLRTSFEQNEGGEPVQRIHDEVPFTLQTAVLGEQTEQEAAASFIQPFDL"
     aSDomain        11527..11610
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOD90_RS21070_NRPS-COM_Nterm.1"
                     /evalue="2.80E-16"
                     /label="MOD90_RS21070_NRPS-COM_Nterm.1"
                     /locus_tag="MOD90_RS21070"
                     /protein_end="30"
                     /protein_start="2"
                     /score="50.4"
                     /tool="antismash"
                     /translation="QQPEIQDIYPLSFMQEGMLFHSLYDEQS"
     aSDomain        11542..12435
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOD90_RS21070_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="1.50E-117"
                     /label="MOD90_RS21070_Condensation_DCL.1"
                     /locus_tag="MOD90_RS21070"
                     /protein_end="305"
                     /protein_start="7"
                     /score="383.9"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHILMDG"
                     /tool="antismash"
                     /translation="QDIYPLSFMQEGMLFHSLYDEQSRAYFEQASFTIHGQLDLERFQK
                     SMDAVFERYEIFRTAFIYKNVAKPRQVVLKHRHCHVHFEDISHLNERDKEHCTEAFKEQ
                     DKSRGFDLQTDVLMRISILKWAPDRYVCIWSHHHILMDGWCLGIVIKDFLHIYQALGKG
                     QLPDLHPVQPYGTYIKWLMQQDREEAAEYWKKRLQHFEKATPLPKRTDQIPDGTLEQIT
                     FTISEKETSELQKIAAASGATLNTVFQALWGIMLQKFNRCGDAVFGSVISGRPSELRDV
                     ENMVGLFINTIPIRVQS"
     aSModule        11542..14643
                     /complete
                     /domains="nrpspksdomains_MOD90_RS21070_Condensation_DCL.1"
                     /domains="nrpspksdomains_MOD90_RS21070_AMP-binding.1"
                     /domains="nrpspksdomains_MOD90_RS21070_PCP.1"
                     /locus_tags="MOD90_RS21070"
                     /monomer_pairings="Glu -> Glu"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       11551..11592
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21070_0001"
                     /evalue="7.20E-05"
                     /label="C1_DCL_004-017"
                     /locus_tag="MOD90_RS21070"
                     /protein_end="24"
                     /protein_start="10"
                     /score="14.7"
                     /tool="antismash"
                     /translation="YPLSFMQEGMLFHS"
     CDS_motif       11614..11730
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21070_0002"
                     /evalue="5.20E-18"
                     /label="C2_DCL_024-062"
                     /locus_tag="MOD90_RS21070"
                     /protein_end="70"
                     /protein_start="31"
                     /score="57.3"
                     /tool="antismash"
                     /translation="AYFEQASFTIHGQLDLERFQKSMDAVFERYEIFRTAFIY"
     CDS_motif       11947..12012
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21070_0003"
                     /evalue="7.70E-11"
                     /label="C3_DCL_135-156"
                     /locus_tag="MOD90_RS21070"
                     /protein_end="164"
                     /protein_start="142"
                     /score="34.4"
                     /tool="antismash"
                     /translation="HHHILMDGWCLGIVIKDFLHIY"
     CDS_motif       12331..12426
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21070_0004"
                     /evalue="2.10E-19"
                     /label="C5_DCL_263-294"
                     /locus_tag="MOD90_RS21070"
                     /protein_end="302"
                     /protein_start="270"
                     /score="61.9"
                     /tool="antismash"
                     /translation="DAVFGSVISGRPSELRDVENMVGLFINTIPIR"
     CDS_motif       12472..12588
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21070_0005"
                     /evalue="1.40E-18"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="MOD90_RS21070"
                     /protein_end="356"
                     /protein_start="317"
                     /score="59.3"
                     /tool="antismash"
                     /translation="QKDMTEAEAYSYFPLYDIQAQSALKQELIDHIIVFENTP"
     aSDomain        12928..14130
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOD90_RS21070_AMP-binding.1"
                     /evalue="1.30E-111"
                     /label="MOD90_RS21070_AMP-binding.1"
                     /locus_tag="MOD90_RS21070"
                     /protein_end="870"
                     /protein_start="469"
                     /score="365.1"
                     /specificity="substrate consensus: Glu"
                     /tool="antismash"
                     /translation="FERQAAVTPERPAIRFSGGSLTYAELDMYAGRLAARLAARGVTKE
                     SIVGVLSERSPEMLIAVLAVLKAGGAYLPLDPAYPKERLSYMLKDSGAAFLLVQPGCSA
                     PSFSGEMLEVDMASLASEKAENDVFTPADGGSLAYVIYTSGSTGKPKGVAVEHRQAVSF
                     LTGMQRQSPLQEDDIVMVKTSFSFDASVWQLFWWSLSGASAYLLPPGWEKDPALIVQAI
                     HQESITTAHFIPAMLNSFLDQAEMKALGDGTSLKRVFAGGESLAPHVAARFASLLPQVS
                     LIHGYGPTEATVDAAFYVLDPERDRDRLRIPIGKPVPGARLYVLDPHLAVQPCGVAGEL
                     YIAGSGVARGYLNRPALTEERFLEDPFYPGERMYKTGDLARWLPDGHVEFLGRLDDQVK
                     IR"
     CDS_motif       13114..13155
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21070_0006"
                     /evalue="7.30E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="MOD90_RS21070"
                     /protein_end="545"
                     /protein_start="531"
                     /score="19.0"
                     /tool="antismash"
                     /translation="LAVLKAGGAYLPLD"
     CDS_motif       13339..13398
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21070_0007"
                     /evalue="3.20E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="MOD90_RS21070"
                     /protein_end="626"
                     /protein_start="606"
                     /score="34.9"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGKPKGVAVEH"
     CDS_motif       13924..14013
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21070_0008"
                     /evalue="1.40E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="MOD90_RS21070"
                     /protein_end="831"
                     /protein_start="801"
                     /score="55.7"
                     /tool="antismash"
                     /translation="PCGVAGELYIAGSGVARGYLNRPALTEERF"
     CDS_motif       14095..14160
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21070_0009"
                     /evalue="6.10E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="MOD90_RS21070"
                     /protein_end="880"
                     /protein_start="858"
                     /score="40.5"
                     /tool="antismash"
                     /translation="FLGRLDDQVKIRGYRIEPGEIE"
     aSDomain        14437..14643
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOD90_RS21070_PCP.1"
                     /evalue="2.30E-26"
                     /label="MOD90_RS21070_PCP.1"
                     /locus_tag="MOD90_RS21070"
                     /protein_end="1041"
                     /protein_start="972"
                     /score="83.8"
                     /tool="antismash"
                     /translation="EMKLAQLWEDVLKNGPVGIHDNFFDRGGHSLKATALVSRIAKEFD
                     VQVPLKDVFAHPTVEGLASVIREG"
     CDS_motif       14758..14865
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOD90_RS21070_0010"
                     /evalue="3.00E-18"
                     /label="C2_LCL_024-062"
                     /locus_tag="MOD90_RS21070"
                     /protein_end="1115"
                     /protein_start="1079"
                     /score="58.2"
                     /tool="antismash"
                     /translation="YNMPAVLELEGKLDPERLDRAFKELIKRHESLRTSF"
ORIGIN
        1 cccgcttaag cggtcatgaa gatatcatcg tcggatcacc aatcgtcggc cggccgcaca
       61 aggatcttga gccgatactc ggcatgtttg tgaacacgct ggcgctgcgg acacgcccgg
      121 agggcgggaa gccgtttgtg cagtatttgc aggaagtgcg cgagacagca ttggaagcgt
      181 atgagcatca ggattacccg ttcgaagagc ttgtcgacaa gcttgaattg acacgggata
      241 tgagcaggaa tccagttttt gatgcgatgt ttatccttca aaatatggaa aagcaggaca
      301 tggatctgga agaggtaaaa gtccggcccg ccaatttcgc acatcacatt tctttattcg
      361 atatcacact aatagcaacg gaaacagatg gagccatttg ctgcgaattg gaatttagta
      421 cggaagtatt cctgaaagct acgattgagc gctgggcagc tcattttatc gaatttctgc
      481 atgcggcact ttctaatcct gaaacaaacc tttcacaaat aaacattctt agtgataaag
      541 aaaaacaaaa tatagtcttt gaattcaaca aaactcaagt tgaattttct caaaaagatg
      601 ttccttttca tcgcatattt gaagcgagag ctgaagaaac accagaacat atagctgtta
      661 ttgatgacga aacacagatt agttatcggc ttctaaacga aagagccaat cgactggcac
      721 ggacgttgca aaaaagaaaa gggacgaagc caactgtggc tgttttagcc aagcggtcca
      781 ttgatgcaat tgttggaatc ctagcagtaa tgaaagctgg cggagtgtat atcccaatcg
      841 attcacatta tccaaaagct agaattgaat accttctccg tgatagcgaa gcagacattc
      901 ttcttttgca gcaggagttg aagcatttga tttcaaactc ttctgaatgt gatatatctc
      961 acatctgcct tgatgatgag agctcttatg aagaaaacag ctgcaacctt gacttatctc
     1021 ctgctcctga ggatgtagca tatatcattt atacgtcagg aactacgggc gcgcctaaag
     1081 gcgttattgt cacctatcgg aactttaccc atgcagctct tgcttggcgg caaatttatg
     1141 aactggatca gaagcctgtc agactgcttc aaatggcgag cttttcattt gatgtctttt
     1201 caggagattt agcgagaaca ttgatcaacg gcgggactct aatcgtttgc ccagatgaaa
     1261 agcggctgga acctgctgaa ttatatggaa tcatgaactc tcggcgaatc acgataatgg
     1321 agtcaacgcc ggctctcatt atcccaatta tggagtatgt ataccgtaac aagctcaagc
     1381 ttcctgactt agacatattg attcttggtt ccgacatggt gaaagctcaa gatttcaaaa
     1441 cattgacaga acgctttggc caaagcatgc gcattatcaa tagttatggc gtcacagaag
     1501 caacgatcga ttccagctgc tatgaaacaa ggatgggaga agagtatacg ggagataacg
     1561 tcccaattgg cagcccgcta ccgaatgtac acatgtacgt actcagccag actaatcaaa
     1621 ttcagccgat tggcgttgcc ggcgagctat gcatcagcgg agcaggtgtt gcgaaaggct
     1681 atcataataa acctgactta acgcaaatga aatttacaga aaatccattt gtctccggag
     1741 aaaggctgta cagaaccggt gatcgagcct gctggcttcc aaacggaacg atcacgcttc
     1801 ttggccgaat ggattatcag gtgaagataa atggatacag aattgaaaca gaagaaattg
     1861 aaagtgttct gcttcaaacc gggctggtca gagaagctgc tgttgccgtt cagcatgata
     1921 agaatggaca tgctggttta gcagcatata ttgtgccttc agacgtcaat acgaatactc
     1981 tccgtgctgc tttaacaaag gagctgccgg catatatgat tcccgcgcat ctgattccta
     2041 tagaaaaact gccgctgacc ctaaacggaa agctggacaa aaacgccttg ccggctccaa
     2101 atgatgtgtt cacacgtcca tatacggcac cagttaacga catacaaaaa acgatagcgg
     2161 aaatatggga agatgtcctg tccattgctc gagtcggcat tcacgattcc ttttttgagc
     2221 ttggcggaga ctcaataaaa gcgttacaag tggcagcacg gctggccgct gaaggctgga
     2281 gcatgacaat acgtgactta ttccgttatc caacgattca ggagctaagc ggacatatca
     2341 caccattggc atctcaagct gatcagggac ctgcggaagg tgaagctgat ctcgccccga
     2401 ttcaacgaag atttttcgga caggttcatg cttttcacta ccattacaac cagtccgtca
     2461 tacttttcag tgaaaaagga ttcaatacta atgcgcttcg tcgggcgctg cgtaaaataa
     2521 ccgagcatca cgatgcaatt cgcatggttt ttcaacgaca tcaaaacggc catgtcgttc
     2581 agtataatcg cggaatgaat cacaacgatc atgaactgtt cggccttcac atagcagact
     2641 ggacaaaaga atcactggaa aggactcagt ttgatgaaaa actagccgct gaggaaatcg
     2701 gcattcaaag caaaatgaat gtacaaaaag ggcctctgct gcaagcaggt ttgtttaaaa
     2761 cggcagaagg ggaccatttg ctgattgcgc ttcatcatct tgtgatagat ggcgtttctt
     2821 ggagaatact gcttgaggat ttagctgcag cataccagca ggctttagaa aaacaagaga
     2881 tccaattacc gccaaaaacg gattcttatt tgtcctacgc caatggtctt gcacaaattg
     2941 ctgaaaacaa acaattgctt gcagaaaaat catattggca atcaattttg gacgctcaca
     3001 ctgcttttct gcctaaggac acggaaaatg tgccaggaag actgcaaatg aacagcgata
     3061 cagcggcgtt tgtactatcc ggggactgga ctgaaaaatt gctgtttgaa acccagcaag
     3121 cctatggcac taatgccaac gaacttttgc ttacggcgtt aggaatggcg ctttctgaat
     3181 ggacaggaca tgaccaaatc gtgattagca ctgagggaca cggtagagag gggcatgtgc
     3241 caaacattga tatttcacgg acagttggat ggtttacttc catttatcct attctgctgg
     3301 acatgggtat tcccgagcct ttcgaggatc agctcgcata ccgaattaag acgacaaaag
     3361 atatgctgag aagggtaccg aacaaaggaa ctggttacgg attgttaaca cacataggag
     3421 aactacctca taaagagcct gaggttagct ttaattatct cggccaattt agcgaagaga
     3481 aggaagctga aacgtttcaa ttatcatatt accagcctcg ttacgaaata gcgggtgaga
     3541 gagaacgaga gtatgagctg gacatcaatg ccctcattac ggacggaagg cttcaagtaa
     3601 aagcggtata cacccaagtg ttcaaccaac actcaattga gtgttttatg gatcgttttc
     3661 acaggcatct tatcgagatg attgagcatt gttctcagaa aaaaatacgc gaaaaaacgc
     3721 tgagtgattt cagcaataag gaattaacgt tgtctgcatt atctagcatc gaagatctcg
     3781 tgaaagatct ttaacttttg aaaaggtgtg tggaattgat ggcacaagcg gcacagattc
     3841 aagatattta tccgttatcg cacatgcagg aaggaatgct gtttcattca ctgatggatg
     3901 tcagctcaaa agcctatgtc gaacagacct cgtttacgat cacagggaat ctatgcatcg
     3961 actcgtttca aaagagctta aaccttcttg tttcccggta tgatattttc agaacgattt
     4021 ttattaaaga agtccaagat cttacaggtc cgcagcaggt agtcctgtca aaccgggaat
     4081 tgacagtgta tagagaagat ttttctcacc tggccgatca tgaacagcag gctctgatcg
     4141 atgcttttat gaccaaggat cgggaaaaag gatttaattt gcaaaaagat ccgttaatgc
     4201 gtcttgccct ttttgataga ggcaacagcc aatatacatg tgtctggaca catcaccata
     4261 tcatcatgga tggctggtgt ctaggcatta ttcttaaaga gtttttcagc atgtatgatt
     4321 cgctcaaaaa taactcacct gtacggcttg gcagcacggt accgtacagc cgctatattg
     4381 aatggctcgg agaacaagat caagaagaga ctgctgctta ctggagcgaa tatttgaagg
     4441 agtacggcaa tactgcatct atcccccgga taaatccccg cccggcggac ggggattata
     4501 aagccgacca gatcagcttt tctttagcac cggaaatggt tgagaaactg actgaggccg
     4561 cccaaaattg gggagtgaca ttaaacacgt tgtttatgag tatgtggggc gtgctcctcc
     4621 atcgatataa tgccgcagat gacgcagttt ttggctccgt catttcggga cgcccgtcag
     4681 cgattgacgg tattgaatca atggtcggct tgtttattaa tactatccca gtgcgaattc
     4741 gatctgcgga gggcatgacg ttttcttcgc tggccaaagc cgtgcaggag gatattttag
     4801 catctgaaca gcatgggtat tatccgcttt atgaaattca gaaccatagt ccattgaagc
     4861 aagggttgat cgatcatatt tttgtctttg aaaattatcc tgtacagctt gatcaggcgt
     4921 taagtattga gagtgaagac gaggaaaatg cactgaagct tggtgacatt tcaatgtcgg
     4981 agcaaaccaa ttacgacttt aatatcgtta ttgttccggg agaatcattt tatatcaaat
     5041 tcagctacaa cgcagccgtt tatgaacggg aggagatgct gaggattcag gggcatctaa
     5101 aacaagctct agattgcatt ttggcacatc ccgatattgc cgtcagtgac atcaatatcg
     5161 tcccgccgga ggagcaacag gttatccaat tgtttaacga aactgagcgt ccctatgtga
     5221 acaaaacgat atcccaattg ttcgaggaac aagcccgcaa aacacctgaa gctgctgcat
     5281 taaaattggg agacgattgc tggacctatc gccaattaaa tataagagcc aatcagattg
     5341 cgcacgccct gatagaaaaa ggcgttggat ctggagatat cgtggctgtg atgatgaacc
     5401 ggtcaatgga aatgcctgca gctctacttg ggatttggaa agcaggcggc gcttatatgc
     5461 cgcttgatcc aaatttccca gaagaacgtc tttcttttct gctgaaggac agtcaagcag
     5521 ctcaattgct gatagaagaa aaccttatgt cattcatccc gccgcactat aaaggaaata
     5581 tgataacgat agaacgtaca gaaagctacc aatcagcagc tccagatgtg ccgcttggtg
     5641 atctcgccta tttgatctat acgtcgggaa cgacagggcg ccctaaaggt gttctagtta
     5701 atcatcaagg cattgccaat acattgcaat ggagacggga agagtatggc atgaccgaac
     5761 aggatatatc cctccatttg ttttcatatg tgtttgacgg ttgtgtgacg agcttgttta
     5821 ccccgctttt atccggtgcg tgcgtattgc tgacaacgga tgacgaagcg aaggatgtgc
     5881 tagcccttaa acgaaaaata gcccgttata aggtcagtca catgatcatt gttccttccc
     5941 tgtaccgggt gttattggaa gtgatgactg ctgacgatgc aaaaagtctt cgtattgtga
     6001 cattcgctgg tgaagcggtc acgcctgacc tgcttgagat gagcgaaaag atttgtcctt
     6061 ttgcagaatt ggcaaatgaa tacgggccca cagaaaatag tgtggcaaca acaatattgc
     6121 gtcaactgaa cgaaaaagag aggatcacga tcggacaccc gattgcgaac acaaaagtat
     6181 ttgttttaca cggaaatcaa atgcagccga tcggcgcggc gggcgaactg tgtatttccg
     6241 gcgagggtct tgcaaaagga tactacaaac agccagagct tacagacaaa gcattctccg
     6301 atcacccgtt ccttgaaggg gagcgtttat accgaacagg tgatgcaggc cgctttttgc
     6361 cggatggaac gattgaatat ataggacgtt ttgatgatca agtgaaaatt aggggttacc
     6421 gcattgaact gaaagaaatt gaaacggttc ttcgacaggc gccaggagtg aaggaagcag
     6481 cagtactggc ccgtgatgtt tctgctgagg aaaaagagct tgttgcttat atcgttccgg
     6541 aaaagggaaa caatctcccg aatttgtatt ggcatctagc cgggacattg ccgccctata
     6601 tgattcccgc aactattatc aatatcagcc ggatgccatt aacatccagc gggaagcttg
     6661 accggtcagc acttcctgaa ccagaaaaca atgcgagcct cacatatatg ccgccccgaa
     6721 ctttaatcga ggctgatctc gcacatattt ggggagatgt gctgaataaa cagcaaatcg
     6781 gcattcgtga tgatttcttt caattaggcg gacagtcctt aaaagcggcc gcactggtat
     6841 caagaataca taaaaagctt aatatcgagc tgccgatcag tgaggttttt tctaatccga
     6901 cagttgaaag catggcagtc aaattgatga gcttaaaaga acatgctttt acacagattg
     6961 agcctgcgga tcaaagagat gtctatccgc tgtctttctc acaaaaacga ttatatgctc
     7021 tccatcagct ggcagatgac agcacaggct ataacatgcc cgctgtactt gaattacgcg
     7081 gaaatctgga tcgccagcgg ttgagaagtg ttctcacaga acttgtgaat cggcatgaag
     7141 tattgcggac tgtttttgtg tttgacagag gagagcccgt gcagatcatt catccagaga
     7201 tggcttttga tctgaaagag cttgaaatgg aatcagaaca aatgcttgag tccgcaatcg
     7261 aatcttttat caaaccgttt gatctatcgt ccggtccgct ttttagagca tgtgtcatta
     7321 caatgggcaa taatcgcggc tttttgctgc tcgacatgca ccatattatt gccgacggtg
     7381 tctcgatgag cactcttgtc caagaattta ctgacttgta ttgcgaaaaa gagttgccag
     7441 ctttaaacct gcattataag gattttgctg tttggcagca agaaaagtac ccgaaagagc
     7501 tatacaaaaa acaggaggcc tactggctcg atcagcttgg cgggagtctt ccagtattag
     7561 aattaccgct tgataaaaca agaccgcgtc tccctgattt cagcggcgga acaatcgaag
     7621 taaacattga taaagacacg gcagatgagc tgcaccgttt aatggttgaa acgggaacaa
     7681 cgttgtatat gattcttctg gctgtctatt ctattttgct atccaagcta agcaggcaag
     7741 aggatattgt cgtcggctcg cctgctgccg gaagaccgca cgccgatctg gagcgcgtca
     7801 tcgggatgtt cgtaaatact ttagcgatgc gcagccagcc cgagggccac aaaacgttca
     7861 gctcgtattt gcaggatatt cgccacctgg ctctgacggc ttacgagcat caggattatc
     7921 cctttgagga gctggcagat aagctcgata cacatcgaga ggtaaatcgc aacccgctgt
     7981 tcgatgcgat gctcgtgctt caaagcagtg aggatttcca gttcgaagtg cctggtctat
     8041 caatttcgtc tgtcactcca aaacacgata tatctaaatt cgatttgaca ttacacgctg
     8101 aggagcattc gagtgggatt cactgccggt ttgaatacag caccgctctt tttgaagaag
     8161 agaccattgc gcgatgggca tcccatttta ttgaactggt gaaaagtgta acggctgata
     8221 ccgagatgag aatttcggaa atgcaattgc ttcctgctgc agagcgcaat ttgctccttg
     8281 aaaaaatggg acagtatgcc gcttatccga gaaatgaaaa cattgtaagc ttatttgaaa
     8341 agcaagccgc tgaacatccg gagcatctcg cagtggtgta cggtcactct cagcttactt
     8401 atcgagacct gaatgaaaaa gctgagcgga cagctgctat gctgatcaaa caaggggtca
     8461 gaactggcga tatcgtaggt ctgatgctcg atcggtcacc tgctatgatc attggcattt
     8521 tatcgatttt aaaagctgga ggggcctact tgccgattga tcctgaatat cctcaggaac
     8581 gtatcagttt tatgctcaat gacagcgggg caaaaatgtt gctgacagag cgcggccaaa
     8641 acaatcctgc agactacaac gggcctatta tgtatatcga tgaaggtgat agcgactcaa
     8701 ttccggatga tttaaacatt caagaaatcc tatcggatca gccggcatac gtgatataca
     8761 catccggaac gactggccag ccaaagggcg tcattgtcga gcaccgcaat gtgatcagtc
     8821 ttttaaagca tcaaaacttg ccttttgaat ttggccatga agacgtctgg acgttatttc
     8881 attcatattg ctttgatttc tctgtatggg aaatgttcgg tgcgttatta aacggaagta
     8941 cactagtcgt ggtctctaaa gaaacagccc gtgaccccca tgcattccga ttattgttaa
     9001 aaaaagaacg cgtcactgta ctcaatcaga ccccgacagc tttttacagc ctgatgcatg
     9061 aagatcaaaa ccatccggat cgattaaaca tccgatacgt gatttttggc ggcgaagctt
     9121 tacagcccgg catgctgcaa agctggaatg aaaaatatcc tgatactgat ctgatcaata
     9181 tgtacggtat tacagaaaca actgtacatg taacattcaa aaaattgtcc gcagcagaca
     9241 ttgcaaaaaa gaaaagcaat atcggacggc cgctttcaac tctgcaggct tatgtgatgg
     9301 atgctcatat gaatctgcag ccgatcggag ttccagggga gatgtatata ggcggtgaag
     9361 gtgtggcacg gggatatctc aacagagatg agctgaccgc tgaccgtttt gtgcctaatc
     9421 cttatcttcc gggggataga ttataccgaa caggagatct tgctaaacgc ctgtcaaatg
     9481 gcgagctgga atacttaggc cgcattgatg atcaggttaa agtcagagga caccgtattg
     9541 agttaggcga aatccaggcg gctcttcttc agcttccagc tattaaagag gcggctgtca
     9601 tcacaagaac agatgagcaa gggcaagcag ctgtatatgc atacatcgtg acaaaagatc
     9661 aacaggccgc gaatgcatca gaaatccgga cttctctaaa aaccatgctg cctgatttta
     9721 tgctgccggc ccgtttgata cagattgaca gcatcccgct gactgttaat ggaaaacttg
     9781 atcagaaagc cctgccggaa cctgataaac acgattatat tgctgatgat atcagaccaa
     9841 gaaatgagat tgaaaaggtg atggctgaaa tttgggagga gcttcttgat gtggaggagc
     9901 tgggcgtaag cgccaatttc tttgagcttg gcggagattc tattaaagca ctgcaagttt
     9961 gtgccagact gaagcaatgc ggctttgaaa cgacagtacg tgagatgttt gaacatcaga
    10021 ctcttggcga actgtccgct cgtgttcgaa aagccgtaca cgtcattgac caaggtccgg
    10081 tcgaaggcga gatcacttgg acacctatcc agcaatggtt tttctcgcaa tctctggaaa
    10141 tccatcattt taatcagtcc gttatgctct atcggactga acgatttgac gagacagcgc
    10201 ttaaaaaggt gctaaaaagc ctggtgattc atcatgacgc actgagaatc gtatgccggt
    10261 atgaaaatgg caggccggtt cagataagca gaggaataga tttgccagat aaggagctat
    10321 atgctcttga actgtttgat ataaaggata acttaacaga agcgcataac aggattaagg
    10381 aagcagccag ccagatgcag gagcatatgc gtttggaaac cggccccttg cttcacgctg
    10441 gattgttcag gaccgagaat ggtgaccatt tgtttctgac gattcatcac ttagttgttg
    10501 atgcggtttc gtggcgcatt ttgttcgagg atttttcaac agcttacaaa caggcagtct
    10561 caggagaatc tattaaactg ccgcaaaaaa cagattcata tttaacgtat tcacaaagaa
    10621 tagctgacta ctctaaaagc cgccagatac agcgagaaga agcgtattgg gatgagcgag
    10681 agaaccgtta cattcagcct attcctaaag acaatgacgc tgcgcataac atattcaaag
    10741 atacagaagt gattgatttt gagctgtccc gccatcacac cgaattgttg ttaacggctg
    10801 cacataaagc atacagcacg gagatgaatg atatccttct gacagcttta ggtcttgctt
    10861 tgcagcaatg gacgggctat gaccagttta aaatcagcat ggagggccat ggaagggaat
    10921 catatcttga ggatattgac attagcagaa cagtcggctg gttcacctcg atttatcctg
    10981 tatggcttga tatgagccat tctgatcata agaacaaaga tgagcggctg ggccatctca
    11041 ttaaacagac aaaagatatg ctgcaccgta taccgcataa gggcgcaggc tacggtgtgc
    11101 tgaaatatac caacaaaaaa tggggctctg agaaaggcag cccggacatc agctttaatt
    11161 atttaggcca gtttgatcag gatattcaat caaaagcctt tgaggtttct gacatcaagc
    11221 cagggaatga gatcagcccg gaatgggagc ggccttatgc actggatatc agcggcgccg
    11281 tttcttcggg atgcctgaac atgcacatga tctataacag gcttcaattt gagaaaaaaa
    11341 caatccaaac atttgcagag cattttaaac agactctgga aaatatcatt gagcattgta
    11401 cgggcaaaga aaaccgagaa tggagcgcat ctgatttcac tgatgaagat ttaacacttg
    11461 atgaattgag tgagattatg ggtgccgtca acaaactata gggagaggag attcacactg
    11521 atgccgcagc aacccgaaat acaggatata taccctttgt cttttatgca ggaagggatg
    11581 ctttttcatt cactgtatga tgaacagtca agagcttatt ttgaacaggc ttcttttacg
    11641 atccatggac agcttgactt ggagcgtttc cagaaaagta tggatgctgt ttttgaaaga
    11701 tacgaaatct tccgaacggc gttcatctat aaaaatgtag ccaaaccacg tcaagtcgtg
    11761 ctcaagcatc gtcattgcca tgttcatttt gaagatattt ctcatctcaa cgaaagagat
    11821 aaagaacatt gtaccgaggc attcaaagag caggataaat ccaggggatt cgatctccaa
    11881 acagatgtac tgatgagaat atctatttta aaatgggcgc ctgatcgtta tgtctgtatc
    11941 tggagccatc atcatatttt aatggatggc tggtgtttag gcatcgtcat taaagatttt
    12001 cttcacattt atcaagcgct gggtaaaggt cagcttccgg atttgcatcc cgttcagccg
    12061 tacgggacgt atattaaatg gctgatgcag caagaccgag aagaagcagc tgagtattgg
    12121 aaaaagaggc ttcagcattt cgaaaaagct acgcctctgc cgaaaagaac agatcaaata
    12181 ccggatggga cattagagca gatcacgttc accatttctg aaaaagaaac ctccgaatta
    12241 cagaaaatcg cagcagcttc tggagcgaca ctaaacactg ttttccaagc tttatggggg
    12301 attatgctcc aaaagttcaa tcgctgcggc gatgctgtgt tcggatccgt tatatcaggc
    12361 agaccttctg agctaagaga tgtggaaaac atggtcggac tttttatcaa taccattcct
    12421 attcgagtcc aaagtgattc tctttctttt tctaacctag tcagcaggat gcaaaaggac
    12481 atgactgagg cagaagcata tagttacttc cctttatatg acattcaggc gcagagtgct
    12541 cttaaacaag agctgattga tcatattatc gtctttgaaa atacacccac ccagcaagag
    12601 attgaagggc tgaatcaggc tggatcattt gatttctccg tgaaggattt tgagatggaa
    12661 gaggtgacca attatagctg cagtgtcaaa gtgatcccag gccgtacttt gtacgttcgg
    12721 attcattttc ataccggcgc ctatcaacca agcatgatgt ccgagataaa agattattta
    12781 cagcacatgg tctctgatgt catctctgat ccatctcttc ccgtgtcaaa gatgacattg
    12841 ctagatgaga acaaaacacg gaaaatcgtt tctcaaaaca acggggcagt atctgtttcg
    12901 cctgaagccc caaccctgca cggtctgttt gaacgacagg cggctgtcac accggaacgg
    12961 ccggccattc gcttttccgg cggttcgctg acgtacgctg agcttgacat gtatgccggc
    13021 cggctggctg cgcgcctcgc ggcacgcggc gtcacgaagg aaagcatcgt cggtgtcctg
    13081 tctgagcggt cacctgaaat gctgatagct gtacttgctg tcttgaaggc aggcggggcg
    13141 tatttgccgc ttgatcctgc atatccaaag gagcggctga gctacatgct gaaagacagc
    13201 ggggccgcgt tcttgctggt acagccggga tgttccgcac cgagcttttc cggagaaatg
    13261 cttgaagtgg acatggcatc tcttgcgagc gaaaaagcag aaaacgatgt gtttactcct
    13321 gctgacggcg gttctctcgc ctatgtcatc tatacgtcgg gctccaccgg gaagccaaaa
    13381 ggggtagccg ttgagcaccg ccaggctgtt tcctttctga ctggcatgca gcgtcagtct
    13441 ccgcttcagg aagatgacat tgtcatggtg aaaacctctt tttcctttga tgcgtctgtg
    13501 tggcagctgt tttggtggtc cctttccggc gcttcggctt atctgcttcc gcccggatgg
    13561 gaaaaagacc cggcattgat cgtacaagcc attcatcagg aaagtattac aacggcccat
    13621 tttattccgg ctatgctgaa cagctttctg gatcaagcgg aaatgaaagc gctcggtgat
    13681 gggacaagcc tgaagcgtgt attcgccgga ggtgaatcac ttgcgcccca tgtggcagcc
    13741 cgttttgctt ctttattgcc gcaggtatcg ctgattcatg gctacgggcc gacagaagcg
    13801 acggtagacg cggcatttta cgtgttggat ccagagcggg acagggatcg cttgcggatt
    13861 ccgattggaa aacccgtacc cggtgcgcgt ttgtatgttt tagatccgca tttagccgta
    13921 cagccttgcg gtgtcgccgg cgaactgtac atagccggat cgggtgtggc cagaggctat
    13981 ttgaatcggc cggcattaac ggaggagcgt tttcttgagg acccgtttta cccgggtgaa
    14041 cgcatgtaca aaaccgggga tttggcgcgc tggcttcctg acggacatgt tgaattcctc
    14101 ggccgtttgg atgatcaagt caaaatcagg ggctaccgga ttgagcccgg agaaattgaa
    14161 gcggtgctaa gaggcataga gggcatcagg gaggcagccg ttaccgtacg gacagacagc
    14221 ggcgagccgg aattatgcgc ctatacagaa gggttcggaa gaaacgaagt gcgggcgcag
    14281 ctcgaaacac ttttaccggg atacatgatc ccagcccata tgatagagat ggaacagtgg
    14341 ccggttacgc caagcggaaa gcttgaccga aacgccctgc cagctcctga cggagcggca
    14401 gatgaggaga cctacacggc gccgagaaat gtgacagaga tgaagcttgc ccagctgtgg
    14461 gaggacgtgc tgaaaaacgg ccctgtcggg attcacgaca acttttttga tcgcggagga
    14521 cattccttaa aagcaaccgc gcttgtttca cggatcgcca aagaattcga tgtacaggtg
    14581 ccgctgaaag atgtgtttgc ccatccgacg gtagaagggc tggcttccgt tatccgtgaa
    14641 ggaacggaca gtccatatga agcgatgaaa ccggctgaaa agcgcgaggc ctatccggtt
    14701 tcctccgcgc aaaaacggat ctatgtcctt cagcagctgg aggacggagg gacaggctac
    14761 aatatgccgg ctgtgttaga gctggaaggg aagctggacc ccgaaaggct ggacagggct
    14821 ttcaaagagc taatcaagcg ccacgagtcg cttcggacat ccttcgaaca gaacgaaggc
    14881 ggcgagccgg tgcagcgtat ccatgacgag gtgccgttta cattacagac agcagtcctc
    14941 ggcgaacaaa ccgaacagga agccgcagcc tcgtttattc agccgtttga tctca
//
