LOCUS       NZ_JALASM010000024     22953 bp    DNA     linear   CON 26-JAN-2024
DEFINITION  Bacillus inaquosorum strain S10C-2 contig_0000024, whole genome
            shotgun sequence.
ACCESSION   NZ_JALASM010000024
VERSION     NZ_JALASM010000024.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus inaquosorum
  ORGANISM  Bacillus inaquosorum
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 57174)
  AUTHORS   Dunlap,C.
  TITLE     Crop Bioprotection Bacillus Genome Sequencing
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 57174)
  AUTHORS   Dunlap,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-FEB-2022) CBP, USDA-ARS-NCAUR, 1815 N. University St.,
            Peoria, IL 61604, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC NGS Cell v. 21
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 216.79422327139883x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/24/2024 02:35:09
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,253
            CDSs (total)                      :: 4,176
            Genes (coding)                    :: 4,061
            CDSs (with protein)               :: 4,061
            Genes (RNA)                       :: 77
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 115
            CDSs (without protein)            :: 115
            Pseudo Genes (ambiguous residues) :: 0 of 115
            Pseudo Genes (frameshifted)       :: 66 of 115
            Pseudo Genes (incomplete)         :: 68 of 115
            Pseudo Genes (internal stop)      :: 20 of 115
            Pseudo Genes (multiple problems)  :: 29 of 115
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:47:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3861
            Orig. end                         :: 26814
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JALASM010000024.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22953
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="sactipeptide"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     cand_cluster    1..22953
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="interleaved"
                     /product="sactipeptide"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..22953
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:12953](-)"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12953)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     misc_feature    330..345
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 20.69"
                     /tool="antismash"
     misc_feature    complement(637..651)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.38"
                     /tool="antismash"
     gene            complement(712..1896)
                     /locus_tag="MOD51_RS20790"
                     /old_locus_tag="MOD51_20740"
     CDS             complement(712..1896)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388087.1"
                     /locus_tag="MOD51_RS20790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD51_20740"
                     /product="DUF4885 domain-containing protein"
                     /protein_id="WP_268282967.1"
                     /transl_table=11
                     /translation="MRLNRQFIRTQLMAQNILNRNAATKRENTSKNTAAMLEKAYSRLE
                     SRSSNEGINQFNYSKTSVAGNGGTFSKVYQSANDRTVTDTGEETVIQSKNPYESESDIR
                     IKILDEKYSRMNAINKTKSDPLGYIKDKYQNSKSPYFRSDLSAAERQAAYDNETEWLFK
                     GKAQNYNLQDAAFRNVTFNGDVEAENGKVYQRSQVNQQLQVLLNRNDIHITQGTELTFT
                     ITPIDYKVQVSGTDDQALIEQIEQVLQSGDNSKELFLHIMKSQSSDSTQFSEEAYKKYQ
                     AAREMYEVTGYHLKDLEVIDGRYVTPDGRDLLDVYKEELQKNPLQKQTASYAISHYRSE
                     LGKIAEAGYDTIPDFILSINYSNGSLRDVGQSKGYGTGDTGWLETLKHQTGVNY"
     protocluster    1484..22719
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[11483:12719](-)"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(11484..12719)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="2"
     misc_feature    complement(1963..1972)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     gene            2029..2886
                     /locus_tag="MOD51_RS20795"
                     /old_locus_tag="MOD51_20745"
     CDS             2029..2886
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388086.1"
                     /locus_tag="MOD51_RS20795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD51_20745"
                     /product="hypothetical protein"
                     /protein_id="WP_119913314.1"
                     /transl_table=11
                     /translation="MMKKWLIPFAIMLSVLFTFTYSASAARVTAITGNNSFDTAAPIGY
                     WKYKNIDTTILEAGQDEAYFTFTANKGEKVYVRSTYQSAYTGMKIEIYDKYRVPVSQGT
                     EVINPNTFSSFIYANADAQNTTDTFYVKVSRGTYTGNMYFTLSIEDRIKSGSGTFQFSG
                     VAENKGNTSLSPSGSDSSVIKVDLTNQSGIPRDAIVTRVQTTTTQTPSQGNTRHFIMTS
                     ENNEWRRALVNSSTSGSYDISLSDQLSVAKVWSFKYNTLATAKSTMSNVKAKIDYEYDV
                     TKQF"
     gene            2984..3754
                     /locus_tag="MOD51_RS20800"
                     /old_locus_tag="MOD51_20750"
     CDS             2984..3754
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388085.1"
                     /locus_tag="MOD51_RS20800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD51_20750"
                     /product="protein kinase"
                     /protein_id="WP_003241418.1"
                     /sec_met_domain="Pkinase (E-value: 4.4e-35, bitscore:
                     113.0, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALKQLKKLLFDRPLKDGVILNHQYKIEECLGMGGYGLVYLCTDV
                     HTQTSYVLKQLRPTKAKKEKERVRFQQEMKLLKSMHHPQIPAFIEDFIIDGQAYYVMQF
                     IEGDNIEELLFFRKQPFTELMALQLISQLLEIVEYLHERLIFHSDIRTPNIIINDGRLC
                     LIDFGLAKQLTPEETEEVKVRKQDDFFDLGETLLFLLYSQYKGKKKKNGTWMEELTLTK
                     EVTLLLKKLLGIDEEYQHTAFIREDLNRAIQSVT"
     gene            complement(3739..3942)
                     /locus_tag="MOD51_RS20805"
                     /old_locus_tag="MOD51_20755"
     CDS             complement(3739..3942)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_003097672.1"
                     /locus_tag="MOD51_RS20805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD51_20755"
                     /product="hypothetical protein"
                     /protein_id="WP_003241419.1"
                     /transl_table=11
                     /translation="MTDIADTGITAAAGADITAATAAAQAKEDTTTVMAAVIVTNAGAT
                     AAVNPKKVLVPLLGQGFFYVTD"
     gene            complement(4060..5046)
                     /locus_tag="MOD51_RS20810"
                     /old_locus_tag="MOD51_20760"
     CDS             complement(4060..5046)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234894.1"
                     /locus_tag="MOD51_RS20810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD51_20760"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_202910186.1"
                     /transl_table=11
                     /translation="MKLKTKYQLLLCTAVISVPVLLLAVSILMSVIYDSMFKPMNHGMP
                     FHRSFAYPAMLVVFLLSLLLLAFLFSKSIHSLLHKINLLNQTIRHLASDQKVPDKIEVK
                     RADEIGELTKSVNLLIERTTYRELELRQQEEIKKELLQKMRHDINTPLTALRLQLFYLE
                     GQCHDQAVFESLYQQIEYISELTNEFNLYSAETLESSYIVNEEVRLNELLETAVKKWDY
                     LYSMNGIELHYKPADQEVIWMSNALWMQRLFDNIFQNTLKHSKAEKMEVTIEHGTVSIR
                     DDGIGFDKTENNEGLGLKIIEDICRLLAITYELQTNENGTGFLFSKE"
     gene            complement(5043..5714)
                     /gene="ybdJ"
                     /locus_tag="MOD51_RS20815"
                     /old_locus_tag="MOD51_20765"
     CDS             complement(5043..5714)
                     /codon_start=1
                     /gene="ybdJ"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388082.1"
                     /locus_tag="MOD51_RS20815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD51_20765"
                     /product="two-component system response regulator YbdJ"
                     /protein_id="WP_225516601.1"
                     /transl_table=11
                     /translation="MKSYHILIVEDDVMIGDLLQKILQREGYHVIWKTDGADVLSVIQK
                     VDLVIMDVMLPGEDGYQMSAKIKKLGLRIPVIFLSARNDMDSKLQGLQIGEDYMVKPFD
                     PRELLLRMKNMLEHHYGTFTQIKHLYIDAETKKVFNESLHDEVLFTAIERKIFFYLYEN
                     RDSTLTKEHFFEYLWQLEDRNPNIVNVHIKKIRAKINDQAGEIIENIYGEGYRLNTVVK
                     K"
     gene            complement(5716..6693)
                     /locus_tag="MOD51_RS20820"
                     /old_locus_tag="MOD51_20770"
     CDS             complement(5716..6693)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388081.2"
                     /locus_tag="MOD51_RS20820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD51_20770"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_268282969.1"
                     /sec_met_domain="PF00561 (E-value: 7.9e-09, bitscore: 27.2,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTLWKVLKIIFGSLAALVLLVSVSVFIYHHYQLNKEAALLKGKG
                     TVVDVDGKKMNVYQEGSGKDTFVFMSGSGIAAPAYEMKGLYSKFSKENKIAVVDRAGYG
                     YSDVSNDDRDIDTVLEQTRKALMKSGNKPPYILMPHSISGIEAMYWAQKYPKEIKAIIA
                     MDIGLPQQYVTYKLSGIDRLKVRGFHLLTSIGFHRFMSSAVYNPEVIRQSFLTDEEKEI
                     YKAINFKQFFNADMEHELLQSYQNGRKSVNLPAPKETPVLILDAVSDQNRNSKYAIQNR
                     KDYEAFAAQFNTADIKELRGTHSIYLYQPDQIYKLSMEFIRKVR"
     gene            complement(6860..7285)
                     /locus_tag="MOD51_RS20825"
                     /old_locus_tag="MOD51_20775"
     CDS             complement(6860..7285)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388080.2"
                     /locus_tag="MOD51_RS20825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD51_20775"
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="WP_268293783.1"
                     /transl_table=11
                     /translation="MKAEQIMNEWPSHLPWLNQSQSDLIFPSDSYYLLYFWSMSCPNCH
                     QLTDQVLQDKKGMNVKVIGVHVPYIEEENSVEVVSTYALDRGIAIPIVLDQNYEIVTTC
                     HVQGIPSFCLLSQYGQIVAKTMGDVGWGKMVKKIKGL"
     gene            complement(7290..7805)
                     /gene="skfG"
                     /locus_tag="MOD51_RS20830"
                     /old_locus_tag="MOD51_20780"
     CDS             complement(7290..7805)
                     /codon_start=1
                     /gene="skfG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388079.2"
                     /locus_tag="MOD51_RS20830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD51_20780"
                     /product="sporulation killing factor biosynthesis/export
                     protein SkfG"
                     /protein_id="WP_019257320.1"
                     /transl_table=11
                     /translation="MKSNGDELSLSVQNLANTNEITIVQAIGKLKKSGKDAIPVLVEAL
                     KEEGSLRNIAAAVLGEFGKDASEAAEELSCLLKSHAEDTRMAAAISLMRIGKPSLPFVT
                     KIAQESEGQSCFWASWCIAWIDPSYIEPKMYECLKHEHEHPSGMVAPFAAEEALGKLIA
                     FQLKDKED"
     gene            complement(7852..9267)
                     /gene="skfF"
                     /locus_tag="MOD51_RS20835"
                     /old_locus_tag="MOD51_20785"
     CDS             complement(7852..9267)
                     /codon_start=1
                     /gene="skfF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019257319.1"
                     /locus_tag="MOD51_RS20835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD51_20785"
                     /product="sporulation killing factor system integral
                     membrane protein"
                     /protein_id="WP_019257319.1"
                     /transl_table=11
                     /translation="MNNIISFLWLQSKRRFVSQGQEKKMPFLIMLLFVGAIGFQVSFVS
                     RSTTWDMSIAGWVLTGVFILYTAFGLFSNRLPSQMEDIIWLYGTATSFSKVVYSVLFFS
                     VTWKALLWIISAIFGDVLIVILSGEHINLLGRSIIFVGLFFIAEVWLMSVSCARTVKKM
                     KRVYVSVFLLMLGIYSMCLYHFFFLQHSSEIWEGIARFISGVGLVFDTLSPLYVVVFIG
                     IITVSFMTIAFTSSQVEMKESLVKEAEFWEEFQERQFGSGQIIQKPKTTWWGLQGLNGI
                     WSFLWLELLLVKKYLFFHSIHTVMLSGVFYVVIFMYPEWFYLLFFLIVSAVMLSSYYSG
                     IVRHSQSGTLHLFPGALWKKIIILELTNTVWLFILYCVSIAFMAVDNLVYWYVYGLGIY
                     IWFMTIRLFAFTNTSRKDLKISLPQYYKSFFMALGLSGICLYGIHLLTAGWYTLMVVVC
                     VGSFCWCLFYRFR"
     gene            complement(9260..9982)
                     /gene="skfE"
                     /locus_tag="MOD51_RS20840"
                     /old_locus_tag="MOD51_20790"
     CDS             complement(9260..9982)
                     /codon_start=1
                     /gene="skfE"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388077.1"
                     /locus_tag="MOD51_RS20840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD51_20790"
                     /product="sporulation killing factor ABC transporter
                     ATP-binding protein SkfE"
                     /protein_id="WP_119913311.1"
                     /transl_table=11
                     /translation="MQLMQVQNLSKCYRNGDGVEHLSFSIQRGEIVALLGPNGAGKTTT
                     IRCLTGLYKPDKGDILIDGSPPGHINVQKKVALIPDQPYLYPALTAAEHIQFRARGFHQ
                     GKKGLKERVYYALKEVHLEEKANELCGQLSRGQKQRVVLAGAIVQDALLYILDEPTVGL
                     DIPSKQWLSNWLKTKTDQGCSAFVSTHSLEFVLETADRVILIRDGKLMQDFYVPQFKEE
                     QAEWRKEVIRLLGEWSDE"
     gene            complement(10001..11491)
                     /gene="skfC"
                     /locus_tag="MOD51_RS20845"
                     /old_locus_tag="MOD51_20795"
     CDS             complement(10001..11491)
                     /codon_start=1
                     /gene="skfC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: skfc"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_003097671.1"
                     /locus_tag="MOD51_RS20845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD51_20795"
                     /product="sporulation killing factor biosynthesis protein
                     SkfC"
                     /protein_id="WP_019257317.1"
                     /sec_met_domain="skfc (E-value: 3e-287, bitscore: 945.2,
                     seeds: 3, tool: rule-based-clusters)"
                     /sec_met_domain="Abi (E-value: 1.4e-14, bitscore: 46.1,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSLPIVFWVILAVVGLMLFIKFKPPTIASLLLSKEEAKEISIQF
                     IKEFVGIDVEKWDFYSVYWYDHDTVNKLHHLGILKKNRKVLYDVGLVESWRVRFVHQNQ
                     SFVVGVNANREITFFYADVPKKSLSGKFEQVSPETLKQRLMASPDGLWSRSNMTGTGKK
                     EEDFREVSTYWYIAEAGDIRLKVTVELQGGRISYIGTEQEILTDQMSKVIRDEQVESTF
                     GVSGMLGSALAMILAILILVFMDVQTSIIFSLVLGLLIIICQSLTLKEDIQLTIVNAYD
                     ARMSVKTVSLLGVLSTLLTGLLTGFVVFICSLAGNALAGDFGWKTFEQPIVQIFYGIGA
                     GLISLGVTSLLFNLLEKNHYLRISPELSNRTVFLSGFTFRQGLNMSIQSSIGEEVIYRL
                     LMIPVIWWMSGNILISIIVSSFLWAVMHQVTGYDPRWIRWLHLFIFGCFLGVLFIKFGF
                     ICVLVAHFIHNLVLVCMPLWQFKLQKHMHHDQPKHTSL"
     gene            complement(11484..12719)
                     /gene="skfB"
                     /locus_tag="MOD51_RS20850"
                     /old_locus_tag="MOD51_20800"
     CDS             complement(11484..12719)
                     /codon_start=1
                     /gene="skfB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Other_Sactipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008343919.1"
                     /locus_tag="MOD51_RS20850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD51_20800"
                     /product="sporulation killing factor system radical SAM
                     maturase"
                     /protein_id="WP_268276175.1"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     4e-15, bitscore: 47.8, seeds: 13, tool:
                     rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 5.6e-32, bitscore:
                     102.8, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 3.9e-22, bitscore: 71.2,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 2e-08, bitscore: 26.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 6e-07, bitscore: 21.7,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNDRVKDFDLPELAVHLQPHGAVMIDRKSMFYFRLSGRGAQLAF
                     LLSKNKNLHKTARIWEIMKKEEMSAGQLKEELSAHPFTEAWTEGLLDQPLYVSGSLDSY
                     LPISCTLQLTNACNLSCSFCYASSGKPYPEELSSEQWILVMQKLAAHGVADITLTGGEA
                     KLIKGFKELVVVASSLFTNVNVFSNGLNWRDVEVELLSHLGNVSVQISIDGMDNTHDQL
                     RGRKGGFKESMNTIKKLSEANIPVIVAMTINESNADEVSDVVEQCANAGAFIFRAGKTL
                     SVGRATEGFKALAVDFEELVQKQLREARDRWGDCLNIIDWEHEESSFTTDFCTPGYLAW
                     YIRADGYVTPCQLEDLPLGHILEDSMADIGSPDRLLQLKCDAKNCKCIGKIELSEPDLP
                     FQKEAKVGIVNE"
     aSDomain        complement(12417..12719)
                     /aSDomain="Other_Sactipeptide_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a sactipeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_MOD51_RS20850_Other_Sactipeptide_rSAM
                     _RRE.1"
                     /evalue="2.10E-15"
                     /identifier="RREFam021.1"
                     /label="MOD51_RS20850"
                     /locus_tag="MOD51_RS20850"
                     /protein_end="101"
                     /protein_start="0"
                     /score="47.8"
                     /tool="antismash"
                     /translation="MSNDRVKDFDLPELAVHLQPHGAVMIDRKSMFYFRLSGRGAQLAF
                     LLSKNKNLHKTARIWEIMKKEEMSAGQLKEELSAHPFTEAWTEGLLDQPLYVSGSL"
     gene            complement(12786..12953)
                     /gene="skfA"
                     /locus_tag="MOD51_RS20855"
                     /old_locus_tag="MOD51_20805"
     CDS             complement(12786..12953)
                     /codon_start=1
                     /gene="skfA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: TIGR04404"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388072.1"
                     /locus_tag="MOD51_RS20855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD51_20805"
                     /product="sporulation killing factor"
                     /protein_id="WP_019257315.1"
                     /sec_met_domain="TIGR04404 (E-value: 2.6e-38, bitscore:
                     121.6, seeds: 3, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRNQKEWESVSKKGLIKPGGTSIVKAAGCMGCWASKSIAMTRVC
                     ALPHPAMRAI"
     misc_feature    13225..13238
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.64"
                     /tool="antismash"
     misc_feature    complement(13226..13239)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.19"
                     /tool="antismash"
     misc_feature    complement(13227..13240)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.64"
                     /tool="antismash"
     gene            complement(13427..>13727)
                     /locus_tag="MOD51_RS20860"
                     /old_locus_tag="MOD51_20810"
                     /pseudo=""
     CDS             complement(13427..>13727)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388059.1"
                     /locus_tag="MOD51_RS20860"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="MOD51_20810"
                     /product="glutamine--fructose-6-phosphate aminotransferase"
                     /pseudo=""
                     /transl_table=11
                     /translation="EGIFADGELKHGTLVLIEQST"
     gene            complement(13849..15021)
                     /locus_tag="MOD51_RS20865"
                     /old_locus_tag="MOD51_20815"
     CDS             complement(13849..15021)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388070.1"
                     /locus_tag="MOD51_RS20865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD51_20815"
                     /product="MFS transporter"
                     /protein_id="WP_268293785.1"
                     /transl_table=11
                     /translation="MSNTWKIYILAIVSFLVGTSEYIISGILDHIAHTLGITLAAAGQL
                     ITIFSLVYALSTPILMALTASMDRRKLMMYALGLFVFGNILAFVLPGYGWFIAARIIMA
                     MGAGMVVVTALTIAAKIASEGKQGSAIATVVMGFTASLIIGVPLGRMIAVALGWKSVFG
                     AIALMGLIAMAVIFFTLPHTEGDKPVPLLQQLALFKKRKVAMGLSITFFWLGGYSVAYT
                     YLSPYLLNISGISGKLLSGVLLIFGIASLVGSKFGGYSTDKWGVPFTLVGGMTLHIITL
                     VGLSFVTHSYIGVLMILILWSFAAWSTGPTQQFHLATIEPEMSGVLLSINQSMMQLAMA
                     VGAGIGGVFVENVSLASITWIGALGVMIAIIASLMIFNSQPKQALKDINR"
     gene            complement(15146..15448)
                     /locus_tag="MOD51_RS20870"
                     /old_locus_tag="MOD51_20820"
     CDS             complement(15146..15448)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_003097670.1"
                     /locus_tag="MOD51_RS20870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD51_20820"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_003234907.1"
                     /transl_table=11
                     /translation="MEPIEVFKALSNESRLQILQWLKEPDRHFAPHEGIDMNTIGVCVS
                     QITDKLKMTQSTASQYLTILLRAGLIKAERIGKYTYYKRDEEAIGKLADFLKTEI"
     gene            complement(15786..16148)
                     /locus_tag="MOD51_RS20875"
                     /old_locus_tag="MOD51_20825"
     CDS             complement(15786..16148)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019257313.1"
                     /locus_tag="MOD51_RS20875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD51_20825"
                     /product="DUF2294 domain-containing protein"
                     /protein_id="WP_003241432.1"
                     /transl_table=11
                     /translation="MKKTKGSIESEISKSITQWEKDYLGRGSVSVKTDILRDMIIVNLK
                     GILTPAEYAVCGSKEGMLSIKQTRSELVESGIEGLKDIILTITGEEVKSFHTDLSSRTG
                     ERVMVFKLCNDLEKNL"
     gene            complement(16205..16495)
                     /locus_tag="MOD51_RS20880"
                     /old_locus_tag="MOD51_20830"
     CDS             complement(16205..16495)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388068.1"
                     /locus_tag="MOD51_RS20880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD51_20830"
                     /product="DUF6407 family protein"
                     /protein_id="WP_003241434.1"
                     /transl_table=11
                     /translation="MNANLTDFVTKTIEEMSSFDRENMECMKKVIRKAIDFYHLKSYEE
                     VEETHLGSVRFLHVHSMMEENMLSKMIVVSRNGKTDLDIEGVYEGHVVREY"
     gene            complement(16562..17086)
                     /locus_tag="MOD51_RS20885"
                     /old_locus_tag="MOD51_20835"
     CDS             complement(16562..17086)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388067.1"
                     /locus_tag="MOD51_RS20885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD51_20835"
                     /product="carbonic anhydrase"
                     /protein_id="WP_133488689.1"
                     /transl_table=11
                     /translation="MNGNQNKKVLFLTDIENGLEPILQEVTNTPAENMLTIQSYGAGIS
                     HPYGEIMRSVIFAIYQEDVEEVVVVGTKDKRTSTGNVLTQLETMKDKIQTLDYLFQNCK
                     PEFLGGTVDEWLNENSTSVEKSVDIIRQHPLVPSYVKVRGLLVHHKDGKASIVEVPDVK
                     TGQALPDHCLS"
     gene            complement(17162..19777)
                     /locus_tag="MOD51_RS20890"
                     /old_locus_tag="MOD51_20840"
     CDS             complement(17162..19777)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388065.2"
                     /locus_tag="MOD51_RS20890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD51_20840"
                     /product="YbcC family protein"
                     /protein_id="WP_268281556.1"
                     /transl_table=11
                     /translation="MGITSVLTKENVKKKDTDIDVQSDLNVLITSASRVIAPLWPISTF
                     AARNPWMGLENQSFDQVAGWLKNSRDVDIYPSASMIRSAKNKGEIDEDFVEMGLQCWLD
                     SHSFNIPRDVAERFCHAGLKLDPLPSTLLSSHKLEKLVNECSGLDHIENVFMQPISSYI
                     ENQDGERLVNILDHHVIKWCKLYLDDSQAGWTMPNREEGFYRAWQHLIQYDPALSKKQR
                     ERLKGWPQEAHLALQEALFALEIPESEIQRYLEGHLLSLPGWAGMMLWRSQQSSHEHAL
                     LTEYLAVRISMEWALIKPYLPIHNERFENKISIAPLIAAWIHWGGLTLEKWPQMSADEQ
                     NEYLSFAYSFDEKLRRKLWLEAWEQTYTDRLSQKIISKQRETNGKKSALAQLAFCIDVR
                     SEPFRRQLEKEGPFETIGIAGFFGVPIATCELGSKHSHASLPVIQKPQNTIKEFADEDV
                     LEKYNQRTQAVHSLSHTFKKMKQNVLTSLLLPELSGPWLSLQMVARSFVPRKTDRFIRN
                     LRETWLRKPDTKLSLHHEYDTEAEIPVGFTEEEKVNHARQALKMMGLTENFAPLVVICG
                     HGSQSINNPYAAALDCGACGGAAGGFNARVLAALCNLSEVREVLLTEGIKIPEDTVFAA
                     AEHNTTVDELHWIYVPKLSEAAQEAFERIEAVMPKVKHNANAERLAQLPNFQSKLKNPK
                     AEAHRFAEDWSEIRPEWGLARNAAFIIGQRELTQDCDLEGRAFLHNYDWKQDESGELLA
                     NIIAGPGTVAQWINLQYYASTVAPHYYGSGNKATQTVTAGLGVMQGNASDLLAGLPWQS
                     VMQSDYEAYHSPLRLLIVIQAPREYVERLLNNDSVFLQKVQNGWVRLASIDPEGCWESW
                     "
     gene            complement(19792..21309)
                     /locus_tag="MOD51_RS20895"
                     /old_locus_tag="MOD51_20845"
     CDS             complement(19792..21309)
                     /EC_number="1.6.5.9"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388064.1"
                     /locus_tag="MOD51_RS20895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD51_20845"
                     /product="NADH dehydrogenase subunit 5"
                     /protein_id="WP_268281557.1"
                     /transl_table=11
                     /translation="MLVSLSLSSLLTLFFIMLIASGISGLLFLHPRVPLSYVRIHIGIL
                     ALPLLVSFLLLANSSVSGDIGLWHLDSLACLMTFFVLAIGFVIQRFSVRYLMGDRSYRK
                     YFTLFTFTTGVASITWLSGDLRLMVIFWGATLVGLTLLIRLNSAWHVASEAAKVSGRLF
                     LLSWFSLFFAMIWLFQVTGQWRLSLVLTNESLAQLGIWERTGIHILIVLAVIIPAAQWP
                     FQRWLIESIVAPTPVSAIMHAGLVNAGGIILTRFSPLFNGGIASIILLLLAGISVLIGT
                     GISLVQVDYKRQLVGSTIAQMGFMLIQCALGAYIAAIIHLILHGLFKATLFLQAGSAVQ
                     RHEGSTRANEGSSYLWIAAGRTLALVIGVAFWLAAPGEGYQLISALILGWSLSVSWTQL
                     VAFGEGKIGRIVGLICLGGAALVYFIIHNLFYKWLHTIDFQSVQPPMSAVIIVVCLLLF
                     GSALGTWVARHRSSVLFAVIYLWLVRLGEAKPKTIESHPDYLKQYLS"
     misc_feature    complement(21513..21531)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 25.12"
                     /tool="antismash"
     misc_feature    21729..21749
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 25.59"
                     /tool="antismash"
     misc_feature    22362..22377
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.78"
                     /tool="antismash"
     misc_feature    22421..22435
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.39"
                     /tool="antismash"
ORIGIN
        1 tcaccattgc cacgatacca ggtatccaag ctggcaaatc cgggaaccaa tacttcatat
       61 aagaaccgac agcgataatt tctgacatgc cgacgataat ccactggaac cagttgctcc
      121 aagctgttat ataacctgcc agcggatgaa tatattgatg gccaaatgtc gcaaaagaac
      181 ccgtgctcgg ctcgacataa agcatttcac ccatcgcacg cataataaaa aagataaaaa
      241 ttccgcatat tgcataagcc agaaggacag acgggccagt ccatgaaatc gtgctggcag
      301 aacccataaa caacccaaca ccgatcgtac cgcctaaggc gatcatctga atatgacgcg
      361 cgccaaggcc cctctttaat tctttatttg ccactcctct tcctcctctt aaccaaaata
      421 ctcgaaaatg ataaaacagc atgcctgctt gccttctcat caatcagtta taacaatcag
      481 aaaattcaaa cttgaaattg ttatataatc tccaaaatta cttatttcat cataataaat
      541 ttctctggaa aatacaattg tttttttgag gtaaacactt ttgttcagag tttttaataa
      601 gaactttgat taaaatcttt tatatgaata taattaaatt gtttgaatat taaaattata
      661 tttcccttat tgattctcat aaaaaataag ctgttcacaa tgaacagctt tctaataatt
      721 cacacccgtt tggtgcttta atgtctcaag ccacccggta tctccggtgc catagccctt
      781 gctttgcccc acatctctta aagatccatt gctgtagtta attgataaga tgaaatcagg
      841 aatcgtatca tacccggctt ccgcaatttt accgagctct gaacggtagt gagatatagc
      901 ataagaagcc gtttgttttt gcagaggatt tttttgaagc tcttctttat atacgtctaa
      961 taagtcacgt ccatcaggcg ttacataccg tccgtcaatc acttctaaat ccttcaaatg
     1021 atagcctgtg acttcataca tctcacgagc agcctgatac tttttatatg cctcttcgga
     1081 aaattgtgtt gaatcactgc tttggctttt catgatatgt aaaaatagct ctttgctgtt
     1141 gtctccagat tgcagcactt gctcaatttg ctcaatcagt gcctgatcgt ctgtcccgct
     1201 cacctgtacc ttatagtcaa tcggcgtaat cgtaaacgtc agctctgtcc cctgcgtaat
     1261 gtgaatatcg tttcggttca atagcacttg tagctgttgg ttaacctggc ttcgctgata
     1321 taccttccca ttctcagcct ccacgtctcc attaaacgtg acattgcgaa acgcagcatc
     1381 ctgcaggtta tagttttgcg ccttcccttt gaataaccat tctgtttcat tatcgtaagc
     1441 ggcctgtctt tctgcagctg acagatcact tctgaaataa ggtgactttg aattttggta
     1501 cttatcctta atatagccta atggatcaga ctttgttttg ttaatcgcat tcatcctgct
     1561 gtatttttca tctagtattt tgattctgat atcactctca gattcatagg ggtttttgga
     1621 ttgaatcact gtttcttccc ctgtgtctgt cactgttcga tcattcgctg attgatacac
     1681 tttgctgaaa gtcccgccgt ttcccgccac actggtttta gaataattga actggttgat
     1741 tccctcattt gaagatcgtg actcaagcct gctgtatgcc ttttccagca tcgccgctgt
     1801 atttttagac gtattctcgc gtttagtagc cgcattccta ttcaatatgt tctgtgccat
     1861 cagctgggtg cggataaatt gccgattcag acgcattggg ttccctcctg aacaattctc
     1921 tcttactctt ttttatcggc aatatcaatg tatatattaa cctcaaaaaa catttattta
     1981 cacctgaaac tttaatatgt atgatggaaa taaaaggagg ttgtttgcat gatgaaaaaa
     2041 tggctcattc catttgctat tatgctgtct gtcttattca cctttactta ttcggcatca
     2101 gctgccagag tcactgctat tacaggaaac aattcatttg ataccgcagc accgatcgga
     2161 tattggaaat ataagaatat cgatacaacg atactggaag ccggacaaga tgaagcctat
     2221 ttcactttta cagctaataa gggagaaaaa gtatacgtga gaagtacata tcagagcgcg
     2281 tacacaggca tgaaaattga aatttacgat aagtacagag tacctgtttc acaaggtaca
     2341 gaagtcatta atcctaacac tttttcttca tttatctatg ctaatgctga cgctcaaaac
     2401 acgacggata ccttctatgt gaaagtgtca cgcggcacct ataccgggaa catgtatttc
     2461 acactttcaa ttgaagaccg aatcaaatcc ggtagcggaa cgttccagtt cagcggcgtt
     2521 gctgaaaata aaggaaacac aagccttagt ccctcaggtt ctgactccag cgtgatcaag
     2581 gttgatttaa caaatcaatc tggaataccg cgcgatgcca ttgtaaccag agtacaaaca
     2641 accaccactc aaacaccaag ccagggaaat acacgccact tcatcatgac gagtgaaaac
     2701 aacgaatggc gccgtgctct tgtgaatagc tcgacttcag ggtcttatga tatatccttg
     2761 tcagatcaac tcagtgtagc aaaggtatgg agttttaaat ataatacatt agcgactgct
     2821 aaatcgacga tgagtaatgt aaaagcaaaa atagattatg aatacgatgt cacaaagcag
     2881 ttttaactta taccgagccg gttatccggc tcttttttat ttttagccta gaaggcaatt
     2941 gttttgataa actataatca gtacaaccaa gggaagtgca gacatggcat taaaacagct
     3001 aaaaaagctc ctttttgacc gccctctaaa ggatggcgtt atcctgaatc atcaatacaa
     3061 aattgaagaa tgcctcggca tgggcggcta tggcttggtt tatttgtgta ccgatgtcca
     3121 tactcaaacc tcttatgtct taaaacagct acggccgaca aaagcgaaaa aggaaaaaga
     3181 aagagtccgg ttccagcagg aaatgaaact gctcaaaagc atgcaccacc cgcaaatccc
     3241 ggccttcata gaagatttca tcattgacgg acaagcttat tatgtcatgc agttcattga
     3301 gggagataac atagaagaat tactattttt tcgaaaacag ccatttacag agctcatggc
     3361 gttacagctg atttcacagc tccttgagat tgtagaatac ctgcatgaac gcctgatatt
     3421 tcatagcgac atcagaacgc ctaatatcat catcaatgac ggcaggctct gcctcatcga
     3481 tttcggcctt gccaaacaat tgactcctga agaaacggag gaagtaaagg tgaggaaaca
     3541 ggatgacttc ttcgatcttg gagaaacgct gttgttcctg ctgtattctc aatataaagg
     3601 aaaaaagaag aaaaacggca cctggatgga ggaattaacg ctcacaaaag aagtaaccct
     3661 gctgttgaaa aaattattag gcattgatga agagtatcag cacaccgctt tcattcgcga
     3721 agatttaaac cgagccattc aatcggtcac ataaaaaaac ccttgtccca aaagcggaac
     3781 aagaactttt tttggattaa ctgctgctgt agctccggcg tttgtaacga tgactgccgc
     3841 cataacggtc gtagtgtctt cttttgcctg agctgctgct gtagctgcgg taatgtctgc
     3901 gccggctgct gctgtaatgc cggtgtctgc gatatcggtc actagagctg cctgagaggt
     3961 acttgatcgt tttgatgatt tttttaaaca ttgctgatca cctcatttct ttcttcctat
     4021 tatatatatt ttatgggaga aagaaaaaca tcagcggggt cactcttttg aaaacaagaa
     4081 ccctgttcca ttctcatttg tctgcagctc ataagtaatc gcgagaagtc tgcatatatc
     4141 ctcaataatc tttaacccaa gcccctcatt gttctcggtc ttatcaaatc caataccgtc
     4201 atcccgaata gaaacagtgc catgttcaat cgtaacttcc atcttttcag cttttgaatg
     4261 ctttaacgta ttttgaaaaa tattatcgaa cagcctttgc atccataacg cgttgctcat
     4321 ccatatcact tcttgatctg ctggcttata gtgcaattca atcccattca tactgtataa
     4381 ataatcccac tttttcaccg ctgtttctaa tagctcgttt aggcgcactt cttcatttac
     4441 gatataagaa ctttctaacg tctcagcgga atatagattg aattcattgg ttagttccga
     4501 gatatattcg atttgctgat acaacgattc gaatacggcc tgatcatgac attggccttc
     4561 caaataaaac aactgcagcc tgagagcggt taaaggtgta ttaatgtcat gacgcatttt
     4621 ttgcaaaagt tcctttttga tttcctcctg ctgtctcagt tccagttcac ggtatgtcgt
     4681 ccgttcaatt aacaaattga ccgatttggt cagttccccg atttcatcag cgcgtttcac
     4741 ttctatttta tcgggcacct tttgatcact cgccagatgc cgaatggttt gatttaatag
     4801 attgatttta tgcagcaggg aatgaatcga ctttgaaaat aaaaaagcta acaataagag
     4861 tgataacaaa aatacaacga gcattgccgg atacgcaaaa gacctgtgaa aaggcatacc
     4921 atgattcatc ggtttaaaca tgctgtcata aattacagac atcaaaatac taaccgccag
     4981 caatagcacc ggaacactaa taacggccgt acataataac agctgatatt ttgtctttag
     5041 cttcatttct tcacaacggt attcagccga tacccttctc catatatatt ttcaataatc
     5101 tcacccgctt gatcattgat tttggctctt atttttttaa tgtgcacatt gacgatattc
     5161 gggtttctgt cttcgagctg ccacaaatat tcaaagaaat gttcctttgt cagggtgctg
     5221 tccctatttt catataaata aaagaaaatt ttccgctcaa tcgcagtaaa caacacctca
     5281 tcatgcaagc tttcattgaa cacttttttg gtttccgcat caatatacaa atgtttgatt
     5341 tgcgtaaagg tgccataatg atgctcaagc atattcttca ttcttaatag cagctctctc
     5401 ggatcaaagg gcttcaccat ataatcctcg ccgatctgca acccttgaag cttgctgtcc
     5461 atgtcattgc gggccgagag aaaaatgacc ggaatgcgca gccccagctt tttgattttt
     5521 gcagacattt gatatccgtc ttcacccggc agcatcacat ccataatgac caaatccacc
     5581 ttctgaatta ccgaaagtac atccgctcca tctgttttcc atatcacatg atatccctca
     5641 cgctgcaaaa tcttttgcag caaatcacca atcatcacat cgtcttcaac gattaaaata
     5701 tgataactct tcatcctagc gaacctttct gataaactcc atggaaagtt tatatatttg
     5761 atcaggctga tataaataaa tactgtgtgt tcccctcagt tcctttatat cagctgtatt
     5821 aaattgagcc gcaaacgctt cataatcttt tcggttttgt atggcatact ttgaatttct
     5881 attttggtca gagaccgcat ctaaaatcaa gacgggagtt tcttttggcg ccggcagatt
     5941 cacagatttc ctaccgtttt ggtaagactg taaaagctca tgctccatat ctgcattaaa
     6001 aaattgctta aaattaatgg ctttatagat ttctttttct tcatcagtta aaaaagactg
     6061 ccgaatcacc tcaggattat atactgcgga agacataaac cgatgaaaac caatcgaagt
     6121 taacagatgg aaccctctca ctttcagtct gtcaatcccg ctcaatttat acgtgacata
     6181 ctgctgaggc aatccaatat ccatcgcaat aatcgcctta atttccttag gatatttctg
     6241 cgcccaatac atcgcttcga tcccggatat ggaatgaggc attaaaatat aaggaggctt
     6301 atttccgctt ttcataagcg ctttcctcgt ctgttccagt accgtgtcaa tatctctgtc
     6361 atcattagac acatcactgt atccataacc agcccgatca acgacagcaa tcttgttttc
     6421 ttttgaaaac ttactgtaca aacctttcat ctcataagca ggcgcagcaa tccccgaacc
     6481 ggacataaac acaaacgtat ccttcccgct tccctcttga tacacattca tctttttacc
     6541 gtcaacatcg actactgttc ctttaccttt gagcaaggct gcctccttat ttagctggta
     6601 atggtgataa ataaaaacgg agacggaaac aagcaaaacc aaagcagcca agctgccaaa
     6661 aatgattttt aggactttcc ataaagtttt catatgatgc tcctttcacg tgatacggaa
     6721 aggatacgac atgaaaataa atttctgatt aattttggga cgattttatt ttgacattaa
     6781 aaaaccttcc cgctcatagg aaggatcgtt tgaccatagt attcaactgt ttgtcgtaca
     6841 tacttacaag acggaaattt cacaagccct taatcttttt taccatctta ccccaaccga
     6901 catcccccat cgttttagct acgatctgac cgtattgact taatagacaa aagctaggga
     6961 tgccttgtac gtgacaagtt gtgacgatct catagttttg gtctaataca atcggaatgg
     7021 ctattcccct atcaagagca tacgtcgaga caacctccac agagttctct tcttctatat
     7081 aagggacatg tactccgatt actttcacat tcataccctt cttatcttga aggacttggt
     7141 ctgttaattg gtgacagttt ggacagctca ttgaccaaaa ataaagaaga taatacgagt
     7201 cacttggaaa tatcaaatca ctctgtgatt gattcaacca cggtaaatgg cttggccatt
     7261 cattcattat ttgttcagct ttcatccttt caatcctcct tatctttcag ctgaaaagca
     7321 atcagctttc ccaatgcctc ttcagccgca aacggagcaa ccattcctga agggtgttca
     7381 tgctcatgtt ttaagcattc atacatcttc ggttcaatgt aagaaggatc gatccacgca
     7441 atacaccatg atgcccaaaa gcatgattgc ccttcacttt cttgagcgat tttggtgaca
     7501 aagggcagac tgggcttccc gattctcatg agtgagatgg ccgcagccat tcttgtatct
     7561 tcagcatggc tttttaataa acatgacagc tcctccgccg cttcactcgc atctttcccg
     7621 aactcaccta aaacagccgc tgcgatatta cgcaaagagc cctcctcttt taaggcctca
     7681 accaaaacag gtattgcatc ttttcctgat ttctttaact tccctatcgc ttgaacaatt
     7741 gtaatctcat ttgtgttcgc taaattctga acagacagcg acaattcatc accatttgat
     7801 ttcataaaag agcccctctc ctcattttaa aacgataact ccacacatcc actatctgaa
     7861 acgataaaac aggcaccaac aaaagcttcc tacacagaca accaccatta atgtatacca
     7921 accagccgtc agtaaatgaa tgccatacaa acaaatgcca ctcaacccta atgccataaa
     7981 aaatgacttg tagtattgag gcaatgaaat cttaagatct tttcgacttg tattggtaaa
     8041 agcaaatagt cttattgtca tgaaccatat atatatcccc aatccatata cataccaata
     8101 aactaaatta tcaactgcca taaatgcaat agagacacag tagagaataa acaaccagac
     8161 tgtattcgtc agctctagaa taatgatttt tttccaaagg gcaccgggga ataaatgaag
     8221 ggtgcctgat tgagaatgtc tgacaattcc tgaataatag gaacttaaca tgactgccga
     8281 gacgatgaga aagaaaagaa gataaaacca ttctggatac atgaaaatga cgacataaaa
     8341 gacgccactg agcatgaccg tatgaatgct atgaaaaaat aaatattttt ttacaagcaa
     8401 cagttccaac cacaaaaaag accaaatacc atttagacct tgtaagcccc accaagtcgt
     8461 ttttggtttc tgtataattt gacctgaacc aaattgacgt tcctgaaatt cctcccagaa
     8521 ttcagcttct ttcaccaacg attccttcat ttctacctga ctgctcgtaa aagcaattgt
     8581 cataaaagag actgtgatga tcccaataaa tacaaccaca tacaacggtg acaatgtatc
     8641 aaacactaat cccacgccac taataaaacg ggcaatgccc tcccatatct cagatgaatg
     8701 ttggagaaag aagaagtgat aaagacacat ggagtaaatg cctaacatta gaagaaagac
     8761 tgaaacgtat acccttttca ttttcttcac tgttctggca caagagaccg acatcaacca
     8821 cacttcagcg ataaaaaaga gccctacaaa aattatggat cggcctagta aattgatatg
     8881 ctcaccagac agaatcacaa ttaatacatc accgaatatg gctgagatga tccaaagcaa
     8941 cgccttccaa gtgacgctga aaaataaaac actatacaca acttttgaaa aagatgtggc
     9001 agtgccataa agccatataa tatcttccat ttgacttggt aatcgatttg aaaaaagtcc
     9061 aaatgccgta taaaggataa aaacacctgt aagcacccaa ccagcaatac tcatatccca
     9121 tgtcgtagat ctagaaacaa aacttacttg aaatccaatg gccccaacaa aaaggagcat
     9181 gatcaaaaaa ggcatttttt tttcctggcc ttgactgaca aaacgccttt ttgactgaag
     9241 ccataaaaaa gaaatgatat tattcatctg accattcccc cagaagacga atcacttctt
     9301 ttctccattc cgcttgttct tctttgaatt gaggaacata aaaatcctgc atgagtttgc
     9361 cgtctctaat taatatcacc ctgtctgctg tctctaaaac aaactctaga ctatgagttg
     9421 atacaaatgc tgaacaccct tgatcggttt tggtttttaa ccagttagag agccactgtt
     9481 ttgatggaat atcgagacct acagttggct catccaatat ataaagtaag gcatcttgaa
     9541 ctattgcccc cgctaagaca acccgctgct tctggcctct tgacagctga ccacacaatt
     9601 catttgcttt ctcctccaag tgtacttcct tcaatgcata ataaaccctt tcttttagtc
     9661 cctttttacc ttgatgaaat cctcttgccc taaactgaat atgttcagca gcggttaaag
     9721 cgggatacag atatggctga tcaggaataa gcgcgacttt tttttgaaca tttatatgtc
     9781 ctggaggaga accatcaatg aggatatctc ctttatccgg cttatagaga cctgtcaaac
     9841 atcgaattgt cgttgttttt ccagctccat ttggccccaa taacgccacg atttctcctc
     9901 gttgaattga gaaagacaaa tgttcaaccc catcaccatt tcgatagcat ttgcttaaat
     9961 tttgcacttg catcaattgc atcaaatctt ctcctaatca ttagagtgaa gtatgctttg
    10021 gctgatcatg atgcatatgt ttctgaagct tgaactgcca cagcggcata cagacgagta
    10081 ctaaattatg aatgaaatga gctactaata cacaaataaa accaaatttg atgaagagaa
    10141 ctcccagaaa acaaccgaat ataaatagat gcagccaacg tatccacctt gggtcatatc
    10201 cagttacttg gtgcatcacc gcccataaaa aggaagatac aataatggag atgaggatat
    10261 ttccactcat ccaccaaatg actggaatca ttaacagccg atagatgacc tcttctccaa
    10321 ttgaactttg tatgctcata ttcaatcctt gcctaaaggt aaaacctgat agaaagacgg
    10381 ttcggttaga aagctcaggt gaaattcgta aataatgatt tttctccaat aagttaaaca
    10441 gcagagaagt cactcccaaa ctaatgagcc ctgctcctat tccatagaaa atctgaacta
    10501 ttggttgttc aaacgttttc catccaaaat caccagcaag cgcatttcct gccaatgaac
    10561 atataaatac tacaaatcct gttaataatc ctgtaagaag tgtagacaaa acacctaata
    10621 aactgaccgt tttgacactc attcttgcat cataagcatt tacaattgtt aattgaatat
    10681 cttctttcag cgtcaatgac tggcatatta taatcaacaa acccagaaca agactgaaga
    10741 ttatgcttgt ttgcacatcc ataaatacaa ggatgagaat cgcaaggatc atcgctaaag
    10801 ctgaacccag cataccagat actccgaatg tcgattccac ttgttcatct cgaatgactt
    10861 tactcatttg atctgttagt atttcttgtt cagtaccaat ataagaaatt cggccgccct
    10921 gtaattcaac agtcaccttg agccgaatat ctcccgcttc cgctatgtac caataagtac
    10981 taacctcccg aaaatcctcc tcttttttac cagtaccagt catatttgat ctagaccaaa
    11041 gtccatcagg tgaagccatt aacctctgct tgagtgtctc tggagaaact tgttcgaact
    11101 tccccgaaag ggactttttc ggaacatccg cataaaaaaa agtgatttct cgattggcat
    11161 tgacaccaac tacaaatgat tgattttggt gaacgaaacg gactctccat gattcgacca
    11221 accctacatc atataaaacc tttctatttt tcttaagtat gcctaagtga tgaagtttat
    11281 tcactgtatc atggtcatac caatataccg aataaaaatc ccatttctcc acatcaatac
    11341 caacaaactc ttttataaat tgtatactta tttcctttgc ctcttctttg cttaagagta
    11401 gtgaagcaat tgttggaggt ttaaatttga taaataacat taatccaaca actgctaaaa
    11461 taacccaaaa tactattggt aaactattca ttcacgatcc ctaccttggc ttctttttga
    11521 aaaggcaagt caggttccga tagctcaatt ttcccaatac atttgcaatt tttagcatca
    11581 cattttaact gaagcaaacg atcaggtgaa ccaatgtcgg ccatgctatc ctctaaaata
    11641 tgtcctagtg gtaaatcctc taattgacag ggagttacat atccatctgc tctaatgtac
    11701 caggcaagat atcctggtgt acaaaaatct gttgtgaaag aactctcttc atgctcccag
    11761 tcaatgatgt tcaggcagtc tccccatcga tcacgggctt ccctaagctg cttttgaacc
    11821 agctcttcaa aatcaacagc caaagcctta aaaccttctg tcgctcgtcc gacagataac
    11881 gtttttcctg cacgaaagat aaaagcaccc gcattggcac attgctccac cacatctgat
    11941 acttcatcag cattggactc attaatggtc atagcgacaa tcactggaat gtttgcttct
    12001 gataattttt taatggtatt catactttct ttaaagccgc cttttctgcc tcttaattgg
    12061 tcatgtgtat tatccatacc atcaatacta atctgtacag aaacattgcc taagtgacta
    12121 agtaattcaa cttctacatc tcgccagttc aatccattac taaatacatt cacattggta
    12181 aacagcgaac ttgcaacaac gactaattct ttaaaccctt tgatcagctt tgcttcaccc
    12241 ccggtcagcg taatatcagc aactccatgg gctgctagct tttgcataac caatatccat
    12301 tgttcactag atagttcctc aggatatggt ttacctgagc tggcatagca aaacgaacag
    12361 cttaaattac aagcatttgt caactgcaag gtacaactaa taggtaaata tgaatctagc
    12421 gaacccgaaa cgtataaagg ctgatctaac agcccttccg tccaagcctc cgtaaatgga
    12481 tgggcactaa gctcttcttt taattggcca gcactcatct cttctttttt cataatctcc
    12541 caaatacgtg ccgttttatg aaggtttttg ttttttgata acagaaacgc caactgtgct
    12601 ccacgtccac tgagtctaaa ataaaacata ctttttctat caatcattac agcaccatga
    12661 ggctgtaaat gaaccgctaa ctctggcaaa tcaaaatctt taacacgatc atttgacata
    12721 taaaatcccc cttaagagaa aataaggagt ataagcaaat atgctcaact ccctattctc
    12781 aaatgttaaa ttgctctcat agcaggatgc ggaagtgcac aaacacgtgt catagcaata
    12841 ctctttgagg cccaacagcc catacagcca gcagccttca caatcgaagt accccctggc
    12901 tttataaggc cttttttact cacagattcc cattcttttt ggtttctttt cataagtaaa
    12961 acctcctctc aatttttgca tagagtctat agacatagct tccatgcgat acgataatac
    13021 cagaatgcaa ttgtcgaagt aaggggaatt ttgtatatta tcctaaaaat tacattaaat
    13081 agatataaat agaatatttt aaccctttaa agattgaaaa gcttccaagc tatcctctcg
    13141 agaaaaacat gagctcaccc ctaattttca cttatgtttt gaatattgtg ttgctctatg
    13201 aacaacatgt caaaaagacg acccattttt atataaaaat tctgatgcct aatagattga
    13261 caaacaacct ctttaaggaa attaaaccaa gagatgattt tcaaataaac tttggtgatt
    13321 atataaatac aatgacttta attaaatgaa tgaaggctcc tctaatttat atcaatcatc
    13381 catactaaaa accccttcga ctaaataacc aaaggggtta aacttattac tccacaataa
    13441 cactcttcgc aagattacgc agtttatcaa catcacagcg gtgcgatgca gtgcagcata
    13501 gtaagcgatt agctgcaatg gaacaactga aaccaacggg gcaagcgctg cattcacttt
    13561 cccagtatac gaatctgtca tccgcatagt ttaggccttt caagatgatg catgtgtttg
    13621 ctctcccttc tttgacattt ccgcggatgc tgacgaataa cttaagtact ttgttcgatc
    13681 aagacaagcg tgccgtgctt cagctctccg tcggcaaaaa tcccttcagt gggcctttta
    13741 catgacggac tttgaacagc ttgaaaaaaa acacccgctt atattacaag cgggtgttag
    13801 acctttcgaa aagaacttat tgaattttaa gaagtaaaaa aagcagtctt atcgattgat
    13861 atcttttagc gcttgtttcg gttgcgaatt gaaaatcatc aatgatgcaa taatggcaat
    13921 cataacccct aacgcaccaa tccaggtaat cgaagccaat gatacgtttt ctacaaaaac
    13981 gccccctatc cctgcgccaa ctgccatagc gagttgcatc atggactgat taatactgag
    14041 caaaacacct gacatttccg gttctattgt agccaggtga aattgctgtg tcggaccggt
    14101 agaccatgcg gcaaacgacc ataatatgag aatcatcaac acaccgatat aggaatgagt
    14161 gacaaatgac agcccaacca gtgtgatgat atgcaatgtc atcccgccaa caagtgtaaa
    14221 gggcactccc catttatcgg tgctatatcc cccaaacttc gatccaacca aactggcaat
    14281 tccaaatata agcaaaacac cgctaagcag cttgccgctt attcctgaaa tgttcaagag
    14341 atacggtgac agataggtat aagcaacaga atatcccccg agccagaaga aagtgattga
    14401 taatcccatc gccactttcc gttttttgaa aagagcaagc tgttgaagca aaggtacagg
    14461 cttatcccct tcagtatgcg gaagagtaaa gaatataacg gccattgcga tcaaacccat
    14521 caaagcaatt gcaccaaata cagacttcca acctaatgct actgctatca ttcttccaag
    14581 cggaacacca atgattaaag aagcggtaaa tcccataacg acagtagcga tggcactgcc
    14641 ttgcttccct tccgatgcaa tcttagcggc aatcgttaat gcggtgacaa caaccatacc
    14701 tgctcccatc gccataatga tccgcgctgc aataaaccat ccataaccag gcaggacaaa
    14761 ggccaagata ttgccgaaca caaacaaacc gagagcatac atcatcaatt tgcgtctatc
    14821 catacttgct gtcaatgcca taagtatggg tgtggaaaga gcatagacaa gtgaaaagat
    14881 cgtaataagc tggcccgcgg cagccaaggt tatcccgagt gtatgagcaa tgtgatccaa
    14941 aataccggaa ataatatact ctgaggttcc aactaaaaag ctgacaatgg ctaaaatgta
    15001 aattttccaa gtgttagaca taaaatttca ctccttaatc ataataaaca tatcacgaaa
    15061 tatcgatatg ttaattcaaa aaataaacac atcgtaatat gtcgatatgt atggcgtaaa
    15121 aataaacatc ttttgatgtt tatttttata tctctgtttt aagaaagtca gcaagtttcc
    15181 caatggcttc ttcatctctt ttgtaataag tgtactttcc gattcgttcc gccttaatca
    15241 ggccggctct taaaaggatg gtgagatatt gggaagccgt cgattgcgtc attttcaatt
    15301 tgtctgttat ttgactgaca cataccccga ttgtgttcat atcaatccct tcatggggtg
    15361 caaaatgacg atcaggctcc ttcagccatt gtaaaatttg cagccttgat tcatttgata
    15421 aggctttgaa tacttcaatt ggttccatga caattattat atcgttatat tccgatatgt
    15481 caattcgttt tttgatgcta gcttttttta ggcttattta tgactaattc tgtgaaatga
    15541 aactgaggaa agcatcccaa aaaccaaaga cttttgttcc tgcttaaatg tatcataaag
    15601 ctttagaaat tggtctctaa tcatggcatt gtacgctttg gggaacccgg cagtggcttt
    15661 gttaattttg gcgtccgctt agattgtgaa ttaaaacaat gatggcataa ctctaaaaaa
    15721 agaagcggaa gttgattatg ttcaatcagc ttccaacctc tttgacaaac atttaattct
    15781 ttatattaaa gatttttctc taaatcatta cataatttaa ataccatcac tcgttcacct
    15841 gtccgggagc ttaaatcagt atgaaaactt ttcacttctt ctccagttat cgtaaggata
    15901 atatccttaa gaccttctat acctgattca actagctctg aacgagtttg tttgatagat
    15961 aacatcccct cttttgatcc acaaactgcg tattcagctg gtgttaaaat tccttttaaa
    16021 ttaacgatga tcatatcccg cagtatatca gttttaacag atacagaccc acgcccaaga
    16081 taatccttct cccattgagt aatggactta ctgatctctg attcaataga acctttcgtt
    16141 tttttcatat ataacacatc tcctggcaaa aaaattggca tattctatta gttatttcgt
    16201 ctcattaata ttctcttaca acatgtcctt catatacacc ttcaatatcc aaatcagttt
    16261 taccgtttct tgagaccact atcattttgg ataacatatt ttcttccatc atagagtgga
    16321 catgcaaaaa tcgaacgctc cctaaatggg tttcctcaac ctcttcatag gattttaaat
    16381 gataaaaatc gattgctttt ctaattactt ttttcataca ttccatattt tctcgatcaa
    16441 acgagctcat ttcctctatt gttttcgtta caaaatcagt taaattagcg ttcatacaat
    16501 ctccttagaa ctgcttcttt ctccatagat gggtgcgttt agaagctgaa ccttcatttc
    16561 atcatgacaa gcaatgatca ggtagggctt gacctgtttt aacatcagga acctccacaa
    16621 ttgaggcttt tccatcctta tgatgaacga gtaaacctct aactttaaca tatgacggca
    16681 ctagtggatg ctgacgaatg atatcaacac ttttttcaac actagtacta ttttcattta
    16741 gccattcatc gaccgtacca cctaaaaatt caggcttaca attttgaaaa agataatcta
    16801 atgtttgtat tttatccttc attgtctcaa gttgagttag tacattacct gtggaagtcc
    16861 tcttatcttt tgttcctaca acaacaacct cctcaacatc ttcctggtaa atcgcaaaaa
    16921 taacagacct cattatttct ccataaggat gtgagatacc ggcaccatag ctttgtatag
    16981 tcagcatatt ttctgctgga gtgttagtca cttcttgtaa aataggctcc aagccgtttt
    17041 caatgtccgt caaaaataat acttttttat tttgatttcc attcatatag cacacctctt
    17101 ctttatgttt ttcattttta tattgagtaa caaatccatt tgataatatt tagattcata
    17161 attaccagct ttcccagcat ccctctggat caatactagc cagtcggacc catccatttt
    17221 gaactttttg gagaaatact gagtcattat ttaataaccg ttctacatat tctctaggtg
    17281 cttggatgac aattaacaaa cgaagaggag aatgataagc ctcataatct gattgcatga
    17341 cggattgcca aggcagtccg gctaacaagt cacttgcatt cccctgcata actccgagac
    17401 ctgcagtaac ggtttgagtt gctttatttc cgctgccata ataatgaggt gctaccgttg
    17461 atgcgtaata ttgtaaatta atccattggg ccacagttcc aggtcctgca ataatatttg
    17521 ctaggagttc accgctttcg tcctgcttcc aatcataatt atgaaggaag gctcttcctt
    17581 ccaaatcaca atcctgagtt agttcacgtt ggccgataat aaaagcggca ttacgagcca
    17641 gtccccattc cggacgtatc tcactccaat cttccgcaaa tcggtgtgcc tcagccttcg
    17701 ggtttttaag tttcgattgg aaattcggta attgggctag acgttctgca tttgcattat
    17761 gtttcacttt cggcataaca gcttcgatac gttcaaatgc ttcttgtgca gcttcagaaa
    17821 gctttggtac ataaatccag tgtaattcat ccaccgttgt attatgttca gcggcagcaa
    17881 aaaccgtatc ctcagggatt ttaattcctt cagttaaaag aacttctctt acttctgaaa
    17941 gattacataa tgcagctaaa actcttgcat tgaatccacc ggccgctcca ccgcaggcac
    18001 cacagtcaag agctgccgca taagggttat tgatactttg gctgccatgc ccgcatatca
    18061 cgactaatgg tgcgaaattc tctgttaatc ccatcatttt tagagcttgg cgggcatggt
    18121 tcactttttc ttcctcagta aaacctacag gtatttctgc ctctgtgtca tactcatgat
    18181 gaagcgagag ttttgtatca ggtttacgta accaagtctc acggagatta cgaatgaaac
    18241 gatccgtttt tcttggcaca aagctacgtg ctaccatttg cagactaagc caaggcccgc
    18301 ttagctcagg cagaagcaag ctcgtaagta cattctgttt catcttttta aatgtatggc
    18361 ttaatgaatg aaccgcttgc gtgcgttggt tgtatttttc gagtacatct tcatctgcaa
    18421 actcttttat tgtattttgc ggtttttgta tgaccggcaa ggaggcatga ctgtgtttac
    18481 tgccaagttc acaagttgca atcggcaccc caaagaaacc agcaatacca atcgtttcaa
    18541 atggaccttc tttttctagt tgacgacgaa aaggctctga tcgtacatcg atgcagaatg
    18601 ccaattgagc taatgcagat tttttaccat tggtttcacg ttgttttgag atgatcttct
    18661 gacttaatcg atcagtgtat gtttgttccc aagcttctaa ccaaagtttc ctgcgaagtt
    18721 tctcatcaaa gctgtaggca aatgataaat attcgttttg ttcatcggcc gacatctgtg
    18781 gccatttctc taatgtaagt cccccccaat gaatccaagc tgctataagg ggagcaattg
    18841 aaattttatt ctcaaatcgt tcattatgaa taggtaaata tggctttata agagcccact
    18901 ccatggatat tcggaccgct aaatattctg tcaggagtgc atgttcatgg ctcgattgtt
    18961 gggagcgcca aagcatcatc cctgcccatc caggtaagga aagtaaatga ccttcaagat
    19021 aacgctggat ttctgattcg gggatttcta gtgcgaataa cgcttcttgt aaagccaaat
    19081 gtgcctcttg cggccaacct tttaaccttt cacgctgctt tttactaagt gctggatcat
    19141 actgaatgag atgctgccag gcacgataga aaccttcctc acgattgggc attgtccaac
    19201 ctgcttgaga gtcatcaaga tataatttac accacttaat gacatgatga tctaggatat
    19261 tgactaacct ttcaccatct tgattctcta tatatgaact tattggttgc ataaaaacat
    19321 tttcgatatg atccaatcca ctacattcat tcaccaattt ctccagctta tgtgatgata
    19381 aaagggtgga aggcagtgga tctagtttta atccagcatg gcaaaatcgc tctgccacgt
    19441 cccgcgggat gttaaaggaa tgtgaatcaa gccagcactg cagccccatt tccacaaaat
    19501 cttcatcaat ctcaccttta ttctttgctg aacggatcat agatgcacta gggtatatat
    19561 caacatcccg agagtttttc aaccaacctg caacctgatc aaaagattgg ttttcaagcc
    19621 ccatccacgg attacgtgca gcaaatgtgg aaataggcca aagtggcgca atcactcggc
    19681 tggcggatgt aattaaaacg ttaagatcac tttgaacatc aatatctgta tctttctttt
    19741 ttacattttc tttcgttaat acggatgtaa tgcccatctc agattagctc cttatgataa
    19801 atattgttta aggtagtctg ggtgactctc tattgtcttt ggttttgctt cacctaatcg
    19861 cactaaccaa agatagatta ccgcgaagag cactgaagaa cgatgacgag caacccacgt
    19921 acctaaagca ctgccaaata gtaagagaca tacaacaatg atgacagctg acattggagg
    19981 ttgaacactt tgaaaatcga ttgtatgcag ccacttatag aagaggttat gaatgataaa
    20041 atatacgagg gctgctcctc ctaaacatat taagccaaca attcggccaa ttttcccctc
    20101 tccaaaagct acgagctgag tccaagaaac ggacaatgac caccctaaga ttagcgcact
    20161 gattaattga tacccctctc caggagcagc gagccaaaaa gcaacgccta tcactaaggc
    20221 taacgtacgg ccagccgcga tccataaata ggatgatccc tcattagccc gcgtcgatcc
    20281 ttcatgccgc tgtactgctg aaccagcctg taaaaacaac gtagctttga ataaaccatg
    20341 taaaataaga tgaataatgg ctgctatata ggctcctaat gcacactgaa tgagcataaa
    20401 ccccatttgt gcaatcgtgg agcctactag ctggcgttta tagtcaacct ggaccaaact
    20461 aataccagtt ccaatcaata cagagatgcc agcaagcaga agtaaaataa tcgatgctat
    20521 accaccatta aatagaggtg aaaatcgagt tagtataatc ccgcctgcgt ttactaaacc
    20581 tgcgtgcata atcgcagaaa caggagttgg agcaacaata gactcaatta accatctttg
    20641 gaatggccat tgagccgcag gaatgatcac tgctaacaca atcaatatat gaatccctgt
    20701 tctctcccaa atccccagtt gagctaaact ttcatttgtt aaaaccaatg ataaccgcca
    20761 ttgacctgtg acttgaaaaa gccaaatcat cgcgaaaaac aaagaaaacc aacttaacaa
    20821 aaataaccgg ccagaaacct tggctgcttc actagccaca tgccaagcac tgtttaacct
    20881 aataagtaag gttaaaccga caagagttgc tccccaaaat ataaccatca agcggagatc
    20941 gccacttaac catgtaattg aagcaacacc tgtagtgaaa gtgaaaagcg taaaatattt
    21001 tcgatatgat cgatctccca ttaagtaacg tacagaaaaa cgctgaatga cgaaaccaat
    21061 tgcaagaaca aagaaagtca ttaaacaagc taaggaatct aagtgccaaa ggccaatatc
    21121 tccactcaca ctactattgg caagtagcag gaaggaaacc aaaagcggta aagccaagat
    21181 cccaatatga atgcgaacat aactcaaggg tactcgcgga tgtaaaaaca atagtccact
    21241 tatcccagaa gcaataagca taataaaaaa taatgttaat aatgatgaca aactcagcga
    21301 aactaacatt tcaaattctc ccttaggtaa aattctgtct gtaattgaat atacatttct
    21361 ttatctcttt gaataattac ttattttttc caataaaaaa gccgacaact tcaagattca
    21421 atgattatct tagtcattga atcttgaaaa ttgtcggctt cacttcaact aacttcagca
    21481 aagttttttg aagagctacc ttatgattgg tcattttact atatacaata ttttaagttc
    21541 cgtctaaagg aatggaatat cgttaattta gtaccttgat ttataaatta aatcgactta
    21601 tgttactctt tgttttttat taggatactt tttcacccta tcaaaattta aaatgaaata
    21661 ttaaaagaat gctaaaggcc taattttaat aacaaacaaa aataaacatc tgcgccgatt
    21721 attaagttaa gtataagata tgctaaattt taaacattgt caagatgttg gaatacggag
    21781 aatgaagtat caaatccttc tttcccttta aatatacatc ctgaatcttt aaccaaggcc
    21841 tatgatatct accattctaa tttttttgta gaaatacaag aaaaatttta taatcatttt
    21901 ctattttctt gtttaataaa taactgagtt caattagtaa ctataaatga atactggttc
    21961 ctactttatt ttcgacagcc ttaacgacca aaaaattgaa ctagttgttg tggatattgt
    22021 tatagctaga attccccaat ttctccgtag atgtcacttt ccttgaaaat accttcttta
    22081 tattttcata ttcttatggc aatcttaaat atctgtaaaa ctaaacatag ccatctttaa
    22141 aacaaaaaac ccctttggct aaaactgtag ctttgaaata aaggatgatc aaaaataaca
    22201 catgaacctt cagtttacgg caaatttaaa gaatccattt agaaaaaaag atagatcaaa
    22261 atggattcta cagttttgaa tacagatgga atctttataa aagagtttga tcattttagg
    22321 ttacgatttt ttgaacatta gcacccgatt gttgaataaa tctaaaaatt ttttgacttg
    22381 ttttcctttc ttttgaagcg ataaagaagc atgttttcac atttttcata aatttttatg
    22441 gtagtttgaa taacttttag tttagggaat gttaaatata taaaagttga aactgctagg
    22501 cttattaata ctcctgctaa aacatcaaaa ggataatgaa ccccaaccca tatacgggag
    22561 actcccacaa gaacagctaa caatacccat aaaattgacc agcctctctt aaagagccag
    22621 aatgaaatac aatatgagaa gaataaaatt gtatggtcac ttggaaaaga attgtctttt
    22681 tctttatgta tcagtttatt aacctctccc aattcaacaa aaggttgata attcgagtga
    22741 aatgcccctg caaccttccc tatcgtaaag gcacaaatga aagcgataga tgcacaaaga
    22801 atcataattc tattatccgt atctcttgta aaccaaataa aaagaacact tagtgcaagt
    22861 aaaaaaacca tatattcagc aataaaacta aatacaggat tcaaaaaggg atgttctttt
    22921 cctaagtcat taactagtct aaacagtgat ata
//
