LOCUS       NZ_JALAQA010000009     22598 bp    DNA     linear   CON 26-JAN-2024
DEFINITION  Bacillus mojavensis strain CK3O2B-54A contig_0000009, whole genome
            shotgun sequence.
ACCESSION   NZ_JALAQA010000009
VERSION     NZ_JALAQA010000009.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus mojavensis
  ORGANISM  Bacillus mojavensis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 124451)
  AUTHORS   Dunlap,C.
  TITLE     Crop Bioprotection Bacillus Genome Sequencing
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 124451)
  AUTHORS   Dunlap,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-FEB-2022) CBP, USDA-ARS-NCAUR, 1815 N. University St.,
            Peoria, IL 61604, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC NGS Cell v. 21
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 140.74370822004147x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/24/2024 01:51:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,128
            CDSs (total)                      :: 4,067
            Genes (coding)                    :: 3,938
            CDSs (with protein)               :: 3,938
            Genes (RNA)                       :: 61
            rRNAs                             :: 5, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 48
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 78 of 129
            Pseudo Genes (incomplete)         :: 77 of 129
            Pseudo Genes (internal stop)      :: 24 of 129
            Pseudo Genes (multiple problems)  :: 38 of 129
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:31:41
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 40289
            Orig. end                         :: 62887
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JALAQA010000009.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22598
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="1"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22598
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22598
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12598](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12598
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            193..984
                     /gene="pdaA"
                     /locus_tag="MOD07_RS18820"
                     /old_locus_tag="MOD07_18765"
     CDS             193..984
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="pdaA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235: polysaccharide deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388679.1"
                     /locus_tag="MOD07_RS18820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD07_18765"
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="WP_268447342.1"
                     /transl_table=11
                     /translation="MKWMCAICCAAVLLAAGAKQADAVPNEPINWGFKRSVNHQPPDAG
                     KQLNSLIKKYDAFYLGNTKEKTIYLTFDNGYENGYTPKVLDVLKKHHVTGTFFVTGHFV
                     KDQPELIKRMSDEGHIIGNHSFHHPDLTTKTADQIQDELDSVNEEVYKITGKQDNLYLR
                     PPRGVFSEYVLKETKRMGYQTVFWSVAFVDWKINHQKGKKYAYDHMIKQAHPGAVYLLH
                     TVSKDNAEALDDAITDLKKQGYTFKSIDDLMFEKEMKLPSL"
     gene            complement(1020..1883)
                     /locus_tag="MOD07_RS18825"
                     /old_locus_tag="MOD07_18770"
     CDS             complement(1020..1883)
                     /EC_number="1.1.-.-"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1100: 3-hydroxyisobutyrate dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010333403.1"
                     /locus_tag="MOD07_RS18825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD07_18770"
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_268447343.1"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 2.6e-09, bitscore:
                     29.6, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIAVIGLGNMGQPIAQNVLQAGYRLTVYNRTKEKTEEFASQGAQ
                     VAKTPRQAAETADIVVTMLSDDNSVSAVTFGKDGLIEGLSENGIHISMSTISVEFSEKL
                     AAAHAEKGQSFLAAPVLGRPDAAANAALRIIAAGPAEAKKTAKPLLESLSQQVFDVGEE
                     SKTANAAKISINFLLVSMLEALSESFLMMEKYGLEQKQFLAIANALFSSPVYQNYGTIM
                     AEQTFEPAGFKMSLGLKDTNLALAAAEQVSAKLPLAELAKSHFENGIEKGLGDLDWAAL
                     ITCIEK"
     misc_feature    1897..1912
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 21.93"
                     /tool="antismash"
     gene            complement(1983..2942)
                     /gene="corA"
                     /locus_tag="MOD07_RS18830"
                     /old_locus_tag="MOD07_18775"
     CDS             complement(1983..2942)
                     /GO_function="GO:0015087 - cobalt ion transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006824 - cobalt ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="corA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388681.1"
                     /locus_tag="MOD07_RS18830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD07_18775"
                     /product="magnesium/cobalt transporter CorA"
                     /protein_id="WP_268447344.1"
                     /transl_table=11
                     /translation="MINITAITTQHQLLKNIPIERVEQPDIAWYWVDFYGPEETETALL
                     RDFFHFHPLAIEDCFQHMQRPKLDHYDGYRFYVLHALNQETLETEEVDIFQGEKFVVTF
                     HLHETPGIAKVRERLYASPDLFKKGPGHIAYMIMDQLVDEYFPLVYKIEDRLNEIEDSR
                     SHKTYGTLMSEVFELRTDLLHLRRTIIPMRDLLYRILSLDHLKDQRETKAYFSDIYDHL
                     LKLSEIVESNRDMTSDLRDSYVTLNSNRMNAIMMTLTIVSTIFIPLTFIAGVYGMNFDN
                     MPELHWEYGYYAVLGLMAALVIGMLIWFVHKGWFNIFK"
     misc_feature    2977..2991
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.07"
                     /tool="antismash"
     gene            3060..3923
                     /locus_tag="MOD07_RS18835"
                     /old_locus_tag="MOD07_18780"
     CDS             3060..3923
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388682.1"
                     /locus_tag="MOD07_RS18835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD07_18780"
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="WP_268447345.1"
                     /transl_table=11
                     /translation="MWKEKVSVTPPYHFDRVLDRLALDPLNAVDLKARDIRVPIRNKTG
                     DVCIVKVQALGDADEPEFLVSGETEQEDMMKEIKRIFQWEHDLRHVLEHFSKTNLSAIF
                     EEHAGTPLVLDYSVYNCIMKCIVHQQLNLSFAYTLTERFVHTFGEQKDGVWCYPKPETI
                     AALDYQDLRDLQFSMRKAEYAIDTSRMIAEGTLDLSELPQMTDEDIMKKLIKIRGIGPW
                     TVQNVLMFGLGRPNLFPLADIGLQNAIKRHFNLDDKPAKDVMLAMSREWEPYLSYASLY
                     LWRSIE"
     misc_feature    3100..3115
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.09"
                     /tool="antismash"
     gene            4037..5437
                     /gene="rlmD"
                     /locus_tag="MOD07_RS18840"
                     /old_locus_tag="MOD07_18785"
     CDS             4037..5437
                     /EC_number="2.1.1.190"
                     /GO_function="GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="rlmD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388683.1"
                     /locus_tag="MOD07_RS18840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD07_18785"
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="WP_268447346.1"
                     /transl_table=11
                     /translation="MNQQNKKAPVELKVGQTFPLTIKRLGINGEGVGYFKKKVVFVPGA
                     LPGEEVVVQATKVQPKFSEGRIKKIRKASEHRVAPPCPVYEQCGGCQLQHLAYSQQLRE
                     KRDIVIQSLERHTKFKVENMDIRETVGMDNPWNYRNKSQFQIGRSQSGSIIAGLYGLDS
                     HDIVPIKDCIVQHPATNKTTGIVRRILEDFNVSVYNERKRKGDVRTIVTRVGFETGEVQ
                     VVLVTAKDTLPHKEEIVKAIQKRLPEVKSIIQNVNGAKTSVIFGGKSKPLAGHTVIQEM
                     LGDVSFELSARAFFQLNPEQTVKLYDEVKKAAQLTGKEKVVDAYCGVGTIGMWVADGAK
                     EVRGMDVIKESIDDAKKNAKKHGMTNATYVTGTAEHWLPKWTKEGFRPDVVIVDPPRTG
                     CDSTFLDTIKKVKPKRFVYVSCNPSTLAKDLQALSKDYRVEYIQPVDMFPQTAHVEAVA
                     KLVLKSSN"
     gene            complement(6383..7780)
                     /locus_tag="MOD07_RS18845"
                     /old_locus_tag="MOD07_18790"
     CDS             complement(6383..7780)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014469907.1"
                     /locus_tag="MOD07_RS18845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD07_18790"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_268447347.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 1.3e-44, bitscore:
                     145.6, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNLRRISMVFIFVIVSSLQPISSHAEEPNYDESIIINLDSKVSE
                     STINKVQEKYSNIETNYIKELDLLVIDNIKPSQFSAIKDIAKEKLDAKEIIEDKEISLP
                     DKSKQIPAKVAFSSQFTEDNDTLYDSWLWNIKQVTNDYRSYDINKGSHNTKVGVIDSGI
                     DFNHPDLKNNIVDTGESFVPVEDNTQDFYGHGTSVAGIIAANGGVKGVGPNLGLVPYKV
                     FDKNGKSKTSWVISAIVKATEDDMDVINLSLSTFLSKKDKEDRETIKLFEKAFKFARKH
                     NTLIVAAAGNHGYDISNSKKLAQQLGKPKDNILHLPGGDKDVITVSATTAQNTKASYSN
                     YGKNISIAAPGGDLDPSFLDTNKIDLYSLVWTTSPVNIPQTPLSKSLGFQEGYEPTLGT
                     SVAAPIVTATAALLKTEYYEKYGEEMPIRKVEEILYQNTDHVENLDKNEVGSGIVNAYE
                     SLLNIER"
     misc_feature    complement(8194..8208)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 23.9"
                     /tool="antismash"
     gene            8202..9971
                     /locus_tag="MOD07_RS18850"
                     /old_locus_tag="MOD07_18795"
     CDS             8202..9971
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) ABC_efflux"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014469908.1"
                     /locus_tag="MOD07_RS18850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD07_18795"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_268447348.1"
                     /transl_table=11
                     /translation="MTNPNFNSKEFFFLLRKTRPNIRLFILAIFLSGLSAIASTLVPHY
                     LKSLIDYYNILEKINLWDLLGLLAIFLISGVIGAVGSYMLSVVGYNVVANLRNLLWEKI
                     VILPIEFYDKNRSADIASRFVNDTTVIYNLVSNSFSQFINAILIVLFCGFWLFYYDWQL
                     TLVIIVAIPVYLLIFIPLGRILSKLSKMTQSLTGELNVRAVETISSIRLIKSSTAEKLQ
                     VERGKEDIEALRNIGLKQTKWMVILNPIINLMMMLIIISIIGFGGVKLANGSLSPGTFI
                     AFLTLMFYIIGPLNNFGLFFTQIQKTIGATERISQLIYEQGEDQHKGKELAETYKDLVI
                     ENLSFCYGKEDKAFSLNNINLIIKGGSVNALVGPSGSGKTTIISILERYYNPNSGNIYF
                     GEENIELFSLKSWRSQIGYVAQNHDLISGTIRDNLIFGLENPPDEKKIVEACKKAYAWQ
                     FISELPNELETNIGEKGLNLSGGQRQRIAIARMFLKDPSIIFLDEATASLDSHSEQIVN
                     EAMKKLMKDRTAIIIAHRLSTIINADNIIFMENGEVTGQGNHWELKRSHKLYRQFCEQQ
                     FKEDSTDPLVLTN"
     gene            10001..12598
                     /gene="lanKC"
                     /locus_tag="MOD07_RS18855"
                     /old_locus_tag="MOD07_18800"
     CDS             10001..12598
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013351405.1"
                     /locus_tag="MOD07_RS18855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD07_18800"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_268447349.1"
                     /sec_met_domain="micKC (E-value: 1.6e-140, bitscore: 462.5,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 7e-18, bitscore: 57.8,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.7e-18, bitscore:
                     59.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKLVYFQHMSEDSKYYIEKSPNAETDPYEVHNMPNYYTVSTEY
                     KSPWKFYNNPNHTLKEQGWKIHISATMNNAQDILKVVSQIIFKHQIPFKHIKDKQSLFN
                     MNSKHGNRTSSGKFIAIYPSSDNMFFGLLNELYEELKHYENGPYILNDKSWKGSNIYYR
                     YGAFKNIYNERGELCIKDENGNLIPDNRQPYYKIPEFVSDFDQYLDTKNNLLDTQDVSN
                     FNDYEFQGVLRFNNGGGIYTGIRKSDGKKVVIKEGRPKVGLDGQLNDAIDRLNIEYEAL
                     NTLTEVEGVVNVLDYFKAWKHVFLVEEFVEGVTLQSWCAINYPFNIENDKNEYISKVKK
                     IINSLIETIKLVHSKDVGMGDLQPQNIMITPESNVKIIDFEAASALSEENGALQTIGYT
                     NKKNKNHKERDWYALKKVLRFCILPIGPVTDIEESIKKKHDMWIENEFGKDVYQYVVNT
                     ENLCDRYLSDTKEKIFKNNYDSEIKKEMDMSKVINGLRNSIESNMLPNSSLIHGDVRQF
                     VMPSGKLNVLTGGTGAALALYRSGNVNKQVRDWIENVLLKKLHVLNDDIGLFTGRAGIA
                     ATLYELGYIEEAMNLFNNLSYEDMKDISLRSGLSGIGLSLISLYLEEDNDDFLVTSEKI
                     ADQIENRIIEDDKLSATDFAAVPIGLIDGWSGISLFYAALYSVTKKEKYYVKSKEYIEW
                     DLKHCKVDEETNTLQTYDDQNPRLLPYLSGGSIGIGVAIWYLNYVGNNNLFREELEQII
                     NLNKVRIAYSGGLFDGVGSFLLIPSMTKENNEISQQIELALKKLELFLIRKDDQVLFPG
                     NFSFRLADDYYSGSAGIILGINSIQFSNPLYWLPIIKIDSFLNKTKKELLLNN"
     gene            12683..12802
                     /locus_tag="MOD07_RS18860"
                     /old_locus_tag="MOD07_18805"
     CDS             12683..12802
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF038154.3"
                     /locus_tag="MOD07_RS18860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD07_18805"
                     /product="class III lanthipeptide"
                     /protein_id="WP_188323619.1"
                     /transl_table=11
                     /translation="MKEVLELQQFNEKSEVEPAAWTVTLTTISVTLSTISNHC"
     misc_feature    complement(12708..12722)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.39"
                     /tool="antismash"
     gene            12849..12977
                     /locus_tag="MOD07_RS18865"
                     /old_locus_tag="MOD07_18810"
     CDS             12849..12977
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014469909.1"
                     /locus_tag="MOD07_RS18865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD07_18810"
                     /product="class III lanthipeptide"
                     /protein_id="WP_188323620.1"
                     /transl_table=11
                     /translation="MKDVLELQQLSEGSDVEASKGKGGLLTLITTIVGTSTISNNC"
     CDS_motif       12849..12920
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKDVLELQQLSEGSDVEASKGKGG"
                     /locus_tag="MOD07_RS18865_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12921..12977
                     /prepeptide="core"
                     /locus_tag="MOD07_RS18865_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="0.50"
                     /molecular_weight="1738.0"
                     /monoisotopic_mass="1737.0"
                     /core_sequence="LLTLITTIVGTSTISNNC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKDVLELQQLSEGSDVEASKGKGG"
                     /leader_location="[12848:12920](+)"
                     /alternative_weights="1756.0"
                     /alternative_weights="1774.1"
                     /alternative_weights="1792.1"
                     /alternative_weights="1810.1"
                     /alternative_weights="1828.1"
                     /alternative_weights="1846.1"
     gene            13005..13124
                     /locus_tag="MOD07_RS18870"
                     /old_locus_tag="MOD07_18815"
     CDS             13005..13124
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038154.3"
                     /locus_tag="MOD07_RS18870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD07_18815"
                     /product="class III lanthipeptide"
                     /protein_id="WP_187265387.1"
                     /transl_table=11
                     /translation="MNEVLELQQLSKGSEVETAGWTLLTTLIGTSTISNSCNK"
     CDS_motif       13005..13055
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNEVLELQQLSKGSEVE"
                     /locus_tag="MOD07_RS18870_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       13056..13124
                     /prepeptide="core"
                     /locus_tag="MOD07_RS18870_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="-1.30"
                     /molecular_weight="2120.4"
                     /monoisotopic_mass="2119.2"
                     /core_sequence="TAGWTLLTTLIGTSTISNSCNK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNEVLELQQLSKGSEVE"
                     /leader_location="[13004:13055](+)"
                     /alternative_weights="2138.4"
                     /alternative_weights="2156.4"
                     /alternative_weights="2174.4"
                     /alternative_weights="2192.5"
                     /alternative_weights="2210.5"
                     /alternative_weights="2228.5"
                     /alternative_weights="2246.5"
                     /alternative_weights="2264.5"
     gene            13145..13276
                     /locus_tag="MOD07_RS18875"
                     /old_locus_tag="MOD07_18820"
     CDS             13145..13276
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014469912.1"
                     /locus_tag="MOD07_RS18875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD07_18820"
                     /product="class III lanthipeptide"
                     /protein_id="WP_188323621.1"
                     /transl_table=11
                     /translation="MKDVLELQQLNEGSDVEASKGKGGLLTLITTVVGTSTISNNCG"
     CDS_motif       13145..13216
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKDVLELQQLNEGSDVEASKGKGG"
                     /locus_tag="MOD07_RS18875_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       13217..13276
                     /prepeptide="core"
                     /locus_tag="MOD07_RS18875_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="0.70"
                     /molecular_weight="1781.1"
                     /monoisotopic_mass="1780.0"
                     /core_sequence="LLTLITTVVGTSTISNNCG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKDVLELQQLNEGSDVEASKGKGG"
                     /leader_location="[13144:13216](+)"
                     /alternative_weights="1799.1"
                     /alternative_weights="1817.1"
                     /alternative_weights="1835.1"
                     /alternative_weights="1853.1"
                     /alternative_weights="1871.2"
                     /alternative_weights="1889.2"
     gene            13425..13556
                     /locus_tag="MOD07_RS18880"
                     /old_locus_tag="MOD07_18825"
     CDS             13425..13556
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014469912.1"
                     /locus_tag="MOD07_RS18880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD07_18825"
                     /product="class III lanthipeptide"
                     /protein_id="WP_188323621.1"
                     /transl_table=11
                     /translation="MKDVLELQQLNEGSDVEASKGKGGLLTLITTVVGTSTISNNCG"
     CDS_motif       13425..13496
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKDVLELQQLNEGSDVEASKGKGG"
                     /locus_tag="MOD07_RS18880_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       13497..13556
                     /prepeptide="core"
                     /locus_tag="MOD07_RS18880_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="0.70"
                     /molecular_weight="1781.1"
                     /monoisotopic_mass="1780.0"
                     /core_sequence="LLTLITTVVGTSTISNNCG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKDVLELQQLNEGSDVEASKGKGG"
                     /leader_location="[13424:13496](+)"
                     /alternative_weights="1799.1"
                     /alternative_weights="1817.1"
                     /alternative_weights="1835.1"
                     /alternative_weights="1853.1"
                     /alternative_weights="1871.2"
                     /alternative_weights="1889.2"
     gene            13696..13827
                     /locus_tag="MOD07_RS18885"
                     /old_locus_tag="MOD07_18830"
     CDS             13696..13827
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014469912.1"
                     /locus_tag="MOD07_RS18885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD07_18830"
                     /product="class III lanthipeptide"
                     /protein_id="WP_188323623.1"
                     /transl_table=11
                     /translation="MKDVLELQQLNEGSDVEASKGKGGLLTLITTIVGTSTISNNCG"
     CDS_motif       13696..13767
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKDVLELQQLNEGSDVEASKGKGG"
                     /locus_tag="MOD07_RS18885_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       13768..13827
                     /prepeptide="core"
                     /locus_tag="MOD07_RS18885_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="0.70"
                     /molecular_weight="1795.1"
                     /monoisotopic_mass="1794.0"
                     /core_sequence="LLTLITTIVGTSTISNNCG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKDVLELQQLNEGSDVEASKGKGG"
                     /leader_location="[13695:13767](+)"
                     /alternative_weights="1813.1"
                     /alternative_weights="1831.1"
                     /alternative_weights="1849.1"
                     /alternative_weights="1867.2"
                     /alternative_weights="1885.2"
                     /alternative_weights="1903.2"
     gene            14283..14567
                     /locus_tag="MOD07_RS18890"
                     /old_locus_tag="MOD07_18835"
     CDS             14283..14567
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_003097694.1"
                     /locus_tag="MOD07_RS18890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD07_18835"
                     /product="YfzA family protein"
                     /protein_id="WP_021481197.1"
                     /transl_table=11
                     /translation="MDKVYKKRPLYKRSWFQTFLAFLVSQLYFNFVELTGWGPKYREMN
                     GFPANIVELDFFQTYLSFYDNPWFNIITVFLGVFTIIQIITGITKDIRN"
     misc_feature    complement(15179..15195)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: weak, score: 20.73"
                     /tool="antismash"
     gene            15321..16298
                     /locus_tag="MOD07_RS18895"
                     /old_locus_tag="MOD07_18840"
     CDS             15321..16298
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388684.1"
                     /locus_tag="MOD07_RS18895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD07_18840"
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="WP_268447350.1"
                     /transl_table=11
                     /translation="MTDNFWRELPRPFFVLAPMEDVTDVVFRHVVSEAGRPDVFFTEFT
                     NSESYCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPENFRQMSIGMAELGFKGLDINMG
                     CPVPNVAGNGKGSGLICRPEVAAELIQAAKAGGLPVSVKTRLGYTNVDEWRDWLTHVLK
                     QDIANLSIHLRTRAEMSKVDAHWELIPEIKKLRDEVAPDTLLTINGDIPDRQTGLKLAQ
                     EYGVDGIMIGRGIFTNPFAFEKEPKEHSSKELLDLLRLHLDLHDKYSALEARPYKPLPR
                     FFKIYLRGFRGASELRNQCMNTKSTDEVRALLDDFERKYLSGIE"
     gene            16471..16923
                     /locus_tag="MOD07_RS18900"
                     /old_locus_tag="MOD07_18845"
     CDS             16471..16923
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388685.1"
                     /locus_tag="MOD07_RS18900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD07_18845"
                     /product="hypothetical protein"
                     /protein_id="WP_268447351.1"
                     /transl_table=11
                     /translation="MKRLCIIPCGKKKIWDVKPDAGPVRAEDAYLSPFHQACERYAKAF
                     FDEWVILSAKHGFLRPNDIVSGNYDVTFGTGHAEIMTSEELRRQFCEKGFSDIEELVML
                     GGKKYRSVLNAVIGEHQYINWPLSSYKGIGYMLQALNRAVEDKHEL"
     gene            16953..17386
                     /locus_tag="MOD07_RS18905"
                     /old_locus_tag="MOD07_18850"
                     /pseudo=""
     CDS             16953..17386
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388686.1"
                     /locus_tag="MOD07_RS18905"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="MOD07_18850"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKKLVFGLLVIAVFGYGLYIYHIWFADPFSKNAAEQKLVSYVKQT
                     YPEKKRRSRMGYITLKPLNMYSKQTSNLIATQCVRRDFSILK"
     misc_feature    complement(17447..17462)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 22.59"
                     /tool="antismash"
     misc_feature    17560..17573
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.31"
                     /tool="antismash"
     gene            17614..18615
                     /gene="acoA"
                     /locus_tag="MOD07_RS18910"
                     /old_locus_tag="MOD07_18855"
     CDS             17614..18615
                     /EC_number="1.1.1.-"
                     /codon_start=1
                     /gene="acoA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388687.1"
                     /locus_tag="MOD07_RS18910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD07_18855"
                     /product="acetoin:2,6-dichlorophenolindophenol
                     oxidoreductase subunit alpha"
                     /protein_id="WP_268447352.1"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.5e-07, bitscore:
                     23.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELLKREGLSLTEEKALWMYQKMLEIRGFEDKVHELFAEGVLPGF
                     VHLYAGEEAVAVGVCAHLDDGDSITSTHRGHGHCIAKGCDLNGMMAEIFGKATGLCKGK
                     GGSMHIADLDKGMLGANGIVGGGFTLACGSALTAKYKQTKNVSVCFFGDGANNQGTFHE
                     GLNLAAVWNLPVVFIAENNGYGEATPFEYASACDSIADRAAAYNMPGVTVDGKDILAVY
                     QAAEEAIERARNGGGPSLIECMTYRNYGHFEGDAQTYKTKDERVEHLEEKDAIQGFKNY
                     LLKETDEKKLADIEQSVNEAIEKAVSFSQDSPYPKESELLTDVYVSYEKGGM"
     gene            18617..19645
                     /gene="acoB"
                     /locus_tag="MOD07_RS18915"
                     /old_locus_tag="MOD07_18860"
     CDS             18617..19645
                     /EC_number="1.1.1.-"
                     /codon_start=1
                     /gene="acoB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388688.1"
                     /locus_tag="MOD07_RS18915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD07_18860"
                     /product="acetoin:2,6-dichlorophenolindophenol
                     oxidoreductase subunit beta"
                     /protein_id="WP_010333415.1"
                     /transl_table=11
                     /translation="MARVISMSDAINEAMKLAMRRDENVLLIGEDVAGGAAVDHLQDDE
                     AWGGVLGVTKGLVQEFGRSRVLDTPISEAGYMGAAMAAASTGLRPIAELMFNDFIGTCF
                     DQVINQGAKFRYMFGGKAQVPITVRTTYGAGFRAAAQHSQALYGLFTSIPGLKTVVPSN
                     PYDAKGLLLAAIEDNDPVFFFEDKTSYNMKGEVPEEYYTIPLGKADIKREGSDITLFAI
                     GKQVNTALEAAAQLSEKGIEAEVLDPRSLSPLDEDAIFTSLEKTNRLIIVDEANPRCSI
                     ATDIAAIVADKGFDLLDAPIKRITAPHTPVPFSPVLEDQYLPTPDKIVSVTLELLGEPA
                     VN"
     gene            19659..20855
                     /locus_tag="MOD07_RS18920"
                     /old_locus_tag="MOD07_18865"
     CDS             19659..20855
                     /EC_number="2.3.1.-"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388689.1"
                     /locus_tag="MOD07_RS18920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD07_18865"
                     /product="dihydrolipoamide acetyltransferase family
                     protein"
                     /protein_id="WP_268447353.1"
                     /transl_table=11
                     /translation="MAVKVVMPKLGMAMKQGEVSIWNKKVGDPVEKGESIASIQSEKIE
                     MEIEAPEKGTLIDIKVKEGEEVPPGTAICYIGDADESVQEETEEPAAEASRQADPQPPK
                     HENKPANTKKDRLKISPVARKIAEKAGLDLKNLKGTGPGGRIVKDDVTKALSEQKREQA
                     EPVSDQKAQETPVTGMRKVIASRMQESLANSAQLTITMKADITKLAALQKQLSPTAEER
                     HGTKLTMTHFVSRAAVLALQSHPMLNSFYKNERIITHPHVHLGMAVALEKGLVVPVIRH
                     AEKKSLIELAQSISENAKKAREGWAGSEELQGSTFSITNLGAFGVEHFTPILNPPETGI
                     LGIGASYDTPVYLGEEIVRSMVLPLSLTFDHRVCDGAPAATFLKAIKTYLEEPAALIL"
     gene            20876..22252
                     /gene="lpdA"
                     /locus_tag="MOD07_RS18925"
                     /old_locus_tag="MOD07_18870"
     CDS             20876..22252
                     /EC_number="1.8.1.4"
                     /GO_function="GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /GO_process="GO:0051068 - dihydrolipoamide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="lpdA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388690.1"
                     /locus_tag="MOD07_RS18925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOD07_18870"
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="WP_268447354.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2e-69, bitscore:
                     227.0, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLAIIGGGPAGYAAAVSAAQQGKKVLLIDKGSLGGTCLNEGCIP
                     TKSLLESANVLDKIKHAGRFGIELPPGAISVDWNKMQSRKQQVVSQLVQGVQYLMKKNQ
                     IQVVKGEASFLSDKKLLIKGENGKEIREAEQILIATGSEPIELPFAPFDGEWVIDSKDA
                     LALSDIPASLVIVGGGVIGCEYAGLFARLGTKVTIIETAGQLIPAEDEDIARHFQEKLE
                     EDGVEVHTSSRLERVDPAAKTAIWKSGQREFKTKADYVLVAIGRKPRLDGLQLEQAGID
                     FSHKGIPVNEQMQTNVSHIYACGDAIGGIQLAHAAFHEGIIAASHASGRNVKMNEKNVP
                     RCIYTSPEIACIGLTEKQAKHVYGDVQIGEFPFSANGKALIKHQAEGKVKIVVEPEFSE
                     IVGVSMIGPDVTELIGQAAAIMNGEMTADMAEHFIAAHPTLSETLHEALLSTIGLAVHA
                     "
ORIGIN
        1 gaagcaacag acgtagaaga tatagatagg ctcatcggca tgctggatga cctggaagcc
       61 aaatatgaac gatttaaaaa agactgggaa taaaaccgcg cttgccgcgg ttttttatat
      121 tggcataaag cgtcagtata aaatggagcg cctttctgta aaataagaaa aaatgcagaa
      181 ggagcgctgg ccatgaagtg gatgtgtgca atatgctgtg ccgccgtcct gcttgcagca
      241 ggagcaaaac aggcagatgc ggtaccgaat gagccgatta attggggctt taagcgaagc
      301 gttaaccatc agccgccaga tgcgggaaaa cagctgaaca gcctgatcaa aaaatacgac
      361 gcgttttatt taggcaatac taaagaaaaa acaatttatt taacatttga taacggctat
      421 gaaaatggat atacgccaaa ggtgcttgat gtcttaaaaa aacatcacgt gacaggaacg
      481 ttttttgtca ccgggcattt cgtgaaagat cagcccgagc tgatcaaacg gatgtcggat
      541 gaagggcata tcatcggcaa ccactccttt caccatccag atctgacgac aaaaaccgct
      601 gaccaaattc aagacgagct cgattcagtc aacgaagagg tttataagat cacgggaaag
      661 caggacaatc tgtacttacg gccgccgcgc ggcgtgttca gtgaatacgt gctgaaagaa
      721 acgaaacgca tgggctatca aaccgttttc tggtccgtcg cttttgtcga ctggaaaatc
      781 aatcatcaaa aagggaaaaa atacgcctac gatcacatga tcaaacaggc gcatccggga
      841 gcggtttacc tgctccacac tgtctccaag gacaatgccg aggcgctgga cgatgcgatt
      901 accgatctga aaaaacaagg ctataccttt aaaagcattg atgacttgat gtttgagaaa
      961 gaaatgaagc tgccgtcttt gtaaacaaga aagcctctcc gcaatggaga ggcttctttc
     1021 tatttttcta tgcatgttat taaagcggcc caatctaggt ctccaagccc tttttcaata
     1081 ccgttttcaa aatggctttt cgccagctcg gcaagaggga gcttggcgga gacctgctcc
     1141 gcggcggcga gcgccagatt ggtgtccttc aaccctaatg acattttaaa gcccgccggc
     1201 tcaaatgttt gctcggccat gatcgttccg taattttgat atacagggga gctgaaaagc
     1261 gcgttggcga tggctaaaaa ttgcttttgc tctaatccgt atttctccat catcaggaat
     1321 gattcagata acgcctccag catggatacg agcaggaaat tgatgctgat tttcgctgcg
     1381 tttgctgttt tgctttcttc gccgacgtca aacacttgct gactcaagct ttcgagcaga
     1441 ggttttgctg ttttttttgc ttccgcgggt cctgccgcaa ttatccgaag tgcggcgttt
     1501 gctgcggcat ctggtcttcc cagcacagga gcggcgagaa aggattgtcc tttttccgca
     1561 tgggcggccg cgagcttttc tgagaactca acactgatcg tgctcatcga aatgtgaatc
     1621 ccattctctg ataatccttc aatcaatcca tctttaccga atgtcacagc gctgacagaa
     1681 ttgtcatcag aaagcattgt cacgacgata tcagcggtct cagccgcctg gcgaggcgtt
     1741 tttgccactt gggcgccttg ggatgcaaat tcctccgtct tttctttcgt ccgattgtat
     1801 actgtcaaac gatagcctgc ttgtagcacg ttttgggcaa tgggctgtcc catattgcca
     1861 agtccgatca cagcgatttt caatctgatc actccctgaa catttttttc attatataca
     1921 aaacgaacag gatatgctgg aaatcggctt gccaaaataa aaagaacagc ttcacgctgt
     1981 cctcatttaa agatgttgaa ccatccttta tgtacaaacc atatcagcat gccgatcaca
     2041 agggcggcca tcaggccaag cacggcgtaa tatccgtatt cccagtgaag ctccggcatg
     2101 ttgtcgaagt tcatgccgta aacaccggcg ataaacgtga gcgggataaa tatcgtagac
     2161 acgatggtca atgtcatcat aatcgcattc atccggttgg aattcagtgt cacgtagctg
     2221 tcacgcaaat cggacgtcat gtcacggtta gattccacaa tttctgaaag ctttaataaa
     2281 tgatcgtaaa tatcgctgaa gtatgccttt gtttcacgct ggtctttcag atggtcaaga
     2341 cttaaaatcc gatacagcaa atcacgcatc ggaataatgg tccgcctgag atgcaatagg
     2401 tctgttctga gctcaaacac ctcgctcatc agcgtcccgt atgttttgtg gctgcggctg
     2461 tcttcaatct cattcagccg gtcttctatt ttgtacacca gaggaaaata ttcatcaaca
     2521 agctgatcca tgatcatata agcaatatgt cccggccctt ttttaaacag atccggtgaa
     2581 gcatataaac gctcccggac tttggcgata ccgggtgttt cgtgtaaatg aaaggtgacg
     2641 acaaattttt cgccctgaaa gatatcgact tcttcggtct caagcgtttc ctgattcagc
     2701 gcatgaagca cgtaaaagcg atagccgtcg taatggtcaa gcttcgggcg ctgcatatgc
     2761 tgaaaacaat cttcaatcgc aagcggatga aaatgaaaaa aatctctcaa taacgcggtt
     2821 tctgtttcct ccgggccgta aaaatcaacc cagtaccacg caatatccgg ctgttcaacc
     2881 cgttcgatcg gtatattttt taaaagctga tgctgtgttg tgatagcggt aatgttgatc
     2941 ataaacaacc ctccacctgc cattatatca tgcggccttt ttcagaaaag tatacagtgt
     3001 tttctgccgg tttccagcgg cgtggtatac tgaacaaaaa cggaaaaagg gctgatcata
     3061 tgtggaaaga aaaagtatcg gtcacaccgc cgtaccattt tgaccgtgtg ctcgacaggc
     3121 tggcgttaga ccctttgaat gcagttgatc tgaaagcgcg ggacataaga gtgccgatca
     3181 gaaataagac cggtgacgta tgtattgtga aggtgcaggc cttaggcgat gcggacgagc
     3241 ccgagtttct cgtcagcggg gaaacagagc aggaagacat gatgaaggaa atcaaacgga
     3301 tttttcaatg ggaacatgat ttgcggcatg tccttgagca tttctctaaa acgaatcttt
     3361 ccgcgatatt tgaagagcat gcaggcacgc cgcttgtatt ggactacagc gtgtacaact
     3421 gtatcatgaa atgcattgtg caccagcagc tgaatttatc ttttgcgtac accttgacag
     3481 aacggtttgt ccatacgttc ggcgagcaga aggacggcgt gtggtgctat ccgaagccgg
     3541 aaacgattgc ggcgctggat tatcaagatc tgcgcgattt gcaattcagc atgcgaaaag
     3601 cggaatacgc tattgatacg tcgcgaatga tcgccgaagg cacgctcgac ttgtcagagc
     3661 tgccccaaat gacagatgaa gacatcatga agaaactgat caaaattaga ggcatcggcc
     3721 catggacggt acaaaacgtg ctgatgtttg ggctcggacg gcccaattta ttcccgctgg
     3781 ccgatatcgg actgcaaaac gcgatcaaac gccactttaa tttggacgac aaaccggcaa
     3841 aggatgttat gctcgcgatg agcagggagt gggagcctta tttgagctat gcgtctttgt
     3901 atttgtggag gagtatagaa taattcgtct gacaatgaag gaaatcgtgt aaacgtgtta
     3961 tactagaaag atgtgaaaaa accatttcac tttctgccat ccgcagaaag cttcatatag
     4021 aaacggagag aacaacgtga accaacaaaa caaaaaggcg cccgtcgaac tgaaagtcgg
     4081 acagaccttt ccgctgacga ttaaacgtct cgggattaac ggggaaggcg tcggctattt
     4141 caagaaaaaa gtcgtattcg tgcccggcgc gcttccaggt gaagaggttg tcgtccaagc
     4201 gacgaaagtg cagccgaagt tttcggaggg acggatcaag aagattcgca aggcttcgga
     4261 gcatcgggta gcaccgcctt gccctgtcta cgagcagtgc ggcggctgcc agcttcagca
     4321 tcttgcatac agccagcagc ttcgggaaaa gcgcgacatc gtcatccagt ctctggagcg
     4381 ccatacgaag ttcaaagtcg aaaacatgga tattagagaa acggtcggca tggacaaccc
     4441 atggaactac cgtaacaaaa gccaattcca gatcggacgc tcacaaagcg gcagcatcat
     4501 tgccggctta tacggccttg attctcatga tatcgtgcca atcaaagact gcatcgtcca
     4561 gcatccggca accaacaaaa caacaggcat cgtccgtcgc attttagagg acttcaatgt
     4621 gtctgtttat aatgaaagaa aacgaaaagg cgacgtccgc acgatagtga cgagagtcgg
     4681 ctttgaaaca ggcgaagtgc aggtcgtgct tgtcacagca aaagatacgc ttccgcataa
     4741 ggaagaaatc gtcaaagcga tccaaaagcg cctgcctgag gtgaaatcca ttattcaaaa
     4801 tgtaaacgga gcgaaaacct ctgttatttt cggtggaaaa tcaaaacccc tcgccggaca
     4861 taccgtaatt caagaaatgc tcggcgacgt atcttttgaa ttgagcgccc gcgccttctt
     4921 ccagctcaat ccagagcaaa ccgtcaagct gtatgacgaa gtgaaaaaag cggcgcagct
     4981 gaccgggaaa gaaaaagtcg ttgacgcgta ttgcggcgtc ggcaccatcg gcatgtgggt
     5041 ggcggacgga gcgaaggaag tccgcggcat ggacgtcatc aaagaatcaa ttgacgatgc
     5101 caagaaaaat gccaaaaaac acggtatgac aaacgccacg tacgtaacag gaacagccga
     5161 gcactggctc ccgaaatgga cgaaagaagg ctttcgcccg gacgtcgtca tcgttgatcc
     5221 gccaagaacc ggctgtgaca gcacgttcct ggatacgatc aaaaaagtta aaccgaaacg
     5281 ttttgtctac gtttcctgca atccatccac acttgcgaag gatttacagg cgctgtcgaa
     5341 agactatcgc gtggaatata ttcagcctgt ggatatgttt ccgcagacgg ctcatgtgga
     5401 agcggtggcg aagcttgtat taaaatcatc taactaaaat aaacaatttc taatcagatc
     5461 tggatttcgg taaaataaac aattccgatt tccgggtctt tttcatgcgc aaaccttgac
     5521 ttgactgtct tttctgaatt ttatcttcct tcatttcttg gagatcttta ttttaactga
     5581 cgaaaagagt tgaaaaagcg tgttgaaaag cgggtgaaaa acagccattt ttgaacagaa
     5641 aaagtatgaa aatgggggtt cggtaggaaa agtctatttt aactcgaacg gtggaatgcg
     5701 ggttggaagg gtctgattta gaaatgtata ttatttttgt acatagtaag agggaagaga
     5761 tttgtttcgt ctgtaatatt taaaacataa atttacaatt ggagttataa gagaagggag
     5821 ttcatgtctg tccttttgag tggaattgat gaaagcagca ttacttaacg tatttttaaa
     5881 aataataaag aagctagaac acaactaaaa gagtatattc tttggtcaaa taacagctat
     5941 ttcttagtaa attctagctt tctacagtct ttaattcgaa tgttatagaa aaaatgaact
     6001 gcctaaacgt taaccaaggt atacaaagac gacttatttt ctaatgatag gttctaaagg
     6061 agagtggatt aatttcctat ttttattatt tggttggcta atctttgaaa accggcttag
     6121 gtgctgttac atgctgggtt tagtgcggat aaagaaatca acaagcttgt agctaaagaa
     6181 ttgaatactc aggctgtaat aaaatatgac acaagcaact tagtaatagt aagttgcttg
     6241 tgaaatcaac ttgtttagtt attctcaata tctcataaat acggtttatt tcatctctag
     6301 cttcatcatc attatcgtct agtaatcttt ttttatttat caaagtattt ttagtgaaag
     6361 ttcgataact gcttaatatc ttctatctct caatattaag caatgattcg taagcattta
     6421 cgataccgct accaacttca ttcttatcta agttttcaac gtggtctgtg ttctgatata
     6481 agatttcttc aaccttacga attggcatct cctctccgta tttttcgtag tattctgtct
     6541 ttaatagggc tgctgtagca gttactattg gagctgctac acttgtccct aaagtaggtt
     6601 catatccctc ttgaaagcct agtgacttac ttagcggagt ttgcgggata tttacagggg
     6661 aagtagtcca taccaagcta tatagatcaa tcttatttgt atccagaaaa cttgggtcaa
     6721 gatcaccacc tggagctgca attgagatgt tttttccata atttgagtaa gaagcttttg
     6781 tattttgcgc tgtggtggca gatacagtaa ttacatcctt atcaccacca ggaagatgta
     6841 ggatattgtc ctttggttta cctaattgtt gtgcaagttt ttttgaattt gagatatcat
     6901 atccatggtt tccagctgct gcaacaatta aagtattgtg ttttctagcg aatttaaaag
     6961 ctttttcaaa aagttttata gtctctctat cttctttatc tttttttgat aagaaagtag
     7021 ataaacttaa attaattacg tccatatcat cttccgtagc tttaacaatt gcgcttataa
     7081 cccaacttgt tttagattta ccgtttttat caaatacttt atacggcact aaaccaagat
     7141 ttggtccaac tccttttaca cccccattag cagcaattat cccagccaca gaagttccat
     7201 gcccataaaa gtcttgtgta ttatcttcaa ctggaacaaa agactctcca gtatctacaa
     7261 tattattttt gaggtctgga tgattgaaat ctatgcctga atcgattact cctacttttg
     7321 tattatgaga tcctttattt atatcataac ttcgataatc atttgtaact tgcttaatat
     7381 tccataacca actgtcataa agagtgtcat tatcttcagt gaattgtgat gaaaatgcca
     7441 ctttagcagg aatctgttta cttttatcag gaagagaaat ctctttatcc tcaataattt
     7501 cttttgcgtc taatttttct ttagcaatat ctttgattgc tgaaaattgg cttggtttta
     7561 tattatctat taccaataaa tctagttctt taatataatt tgtttctata tttgaatact
     7621 tttcctgaac cttgtttatt gtcgattcac ttacttttga gtcgaggtta attatgatag
     7681 attcatcata atttggttct tcagcatgag agcttatagg ctgtaaactg gatacaatta
     7741 caaatatgaa aaccatcgaa attcttctta aattcttcat tttttatact cctttccctt
     7801 aatacagttc atttaataat aagattgtat ataatttacc ccctttccaa aaataagtat
     7861 attaaattca agtttataaa atataagtaa atcagtcaat acatattttt ctaattatca
     7921 gtaattatcc cgagaaattc acctttagtt tgattaaatt aaacttcttt ttattctttt
     7981 atactacacc tgtggttttg cgggtcaaaa ttactatggg taaatataca tgagtagaat
     8041 aatgcaaaac caaagacctg ttttttcata atttgtaaaa ttatatattg acttgcagtt
     8101 attatgtgtg aaatattgtt tataggaata ttaggaaagg tatcatgagt cattcgattt
     8161 aaaaagtcga aacattggaa taaatggtag aggtgaaaat gatgaccaac cccaatttta
     8221 actcgaaaga gttcttcttc ttactgagaa aaaccagacc gaatataaga ttatttatat
     8281 tggcaatatt tttaagtgga ttaagcgcaa tagcttctac tttagtgcct cattatttaa
     8341 aaagtctaat agactattat aatattcttg aaaagatcaa tttatgggat cttttaggtc
     8401 ttctagcaat atttttaatc agcggagtaa tcggggcagt tggtagttat atgttaagtg
     8461 tagtaggata taacgttgtt gcaaatctca gaaatttatt atgggaaaag atagtaatac
     8521 tacctataga attttacgat aagaatcgtt ctgcagatat agcaagtaga tttgttaatg
     8581 atactacggt gatttacaac ttagtaagta actctttttc gcaatttatt aatgctatat
     8641 taatagtgct tttttgtgga ttttggttgt tttactatga ttggcaattg acattggtga
     8701 ttatcgtagc aattccagtt tatttgttga tttttatacc tttaggaaga attttatcaa
     8761 aattatctaa aatgacacaa agcttaacag gagaattaaa tgtaagagct gttgaaacaa
     8821 tatcctcaat aagactaatt aaatcttcaa ctgcagaaaa attacaagta gaaagaggaa
     8881 aagaagatat tgaagcttta agaaatatag gcctaaagca aacaaaatgg atggttattt
     8941 taaaccctat cattaattta atgatgatgc ttatcattat tagcataatt ggattcggag
     9001 gggttaaatt agccaatgga agtttatcgc caggaacctt tattgcattt ctgacactga
     9061 tgttctatat cataggtcca cttaataact ttgggttatt ctttactcaa atacaaaaga
     9121 cgataggtgc aacagaaaga atttctcaat tgatatatga gcaaggagaa gatcagcata
     9181 aagggaaaga attagcggaa acctataaag atttagtgat tgaaaattta tcattttgct
     9241 atggtaaaga ggataaggca ttttccttga ataatattaa tttaataata aaagggggaa
     9301 gtgtaaatgc cttagtaggt cctagtggta gtggtaaaac cacaatcatc tctattctgg
     9361 aaagatatta taatcctaat agcggaaata tttattttgg tgaagagaat attgagttat
     9421 tttcattaaa atcatggcgt agccaaatag gatatgtagc acagaatcac gatttaataa
     9481 gcggtactat tagagacaat ctcatctttg gtttagaaaa tcccccagat gaaaaaaaaa
     9541 tagtagaagc atgtaagaag gcatatgcat ggcaatttat aagtgaattg cctaacgagt
     9601 tagaaactaa tattggagaa aaaggtctaa acttatcggg aggacaacga caaagaattg
     9661 ctattgcgag aatgtttctg aaggatccaa gtataatctt tttggatgaa gcaactgcaa
     9721 gtcttgacag tcattctgaa caaattgtga acgaagcaat gaagaagctc atgaaggata
     9781 gaaccgctat tataatagca cataggttat ccaccattat aaacgctgac aatatcattt
     9841 ttatggaaaa tggtgaggtg acaggtcaag ggaatcattg ggagttaaag cgtagtcata
     9901 aattgtatcg tcaattctgt gagcagcagt ttaaagaaga tagtaccgat ccattagtat
     9961 taaccaatta aaaagagcgc ttaagagagg cgagaacaaa atggacaaaa aattagttta
    10021 tttccaacac atgagtgaag attcaaagta ctatatagag aaaagcccaa atgcagagac
    10081 tgatccatac gaagtacata atatgccaaa ttattatact gttagtacag aatataaatc
    10141 accgtggaag ttttataata atcccaatca taccctcaaa gaacaaggct ggaaaataca
    10201 cataagtgcg acaatgaata atgctcagga tatattaaaa gttgtgagtc aaattatatt
    10261 taaacatcag ataccattta agcatattaa agataaacaa tctcttttta atatgaattc
    10321 aaagcatggt aatcgaactt catctggaaa atttatcgct atctatcctt cttctgataa
    10381 catgttcttc gggttattaa atgaacttta tgaagaatta aaacactacg agaatggacc
    10441 atacatatta aatgacaaat catggaaggg tagcaatata tattaccgat acggtgcatt
    10501 taagaatatt tacaatgaaa gaggagaact ttgcattaaa gacgaaaatg gaaatttaat
    10561 cccagacaat aggcagccat attataaaat acctgaattc gtaagtgatt ttgatcaata
    10621 tttagatacc aagaataact tattagatac tcaagatgta agtaatttta atgattatga
    10681 gttccaagga gtccttaggt ttaacaatgg tggcggtata tatacaggaa taagaaaatc
    10741 agatggaaag aaagtggtga tcaaagaagg gagacctaaa gtaggattag atggtcaatt
    10801 aaatgatgcg attgatagat tgaatataga atacgaagca ttaaatacac ttacagaagt
    10861 tgaaggtgtt gttaatgtgc tcgattactt taaagcatgg aaacatgtat ttttagttga
    10921 agaatttgta gaaggtgtaa cccttcaatc atggtgtgca atcaattatc ctttcaacat
    10981 tgagaatgat aaaaatgaat acattagtaa ggtgaaaaaa ataattaata gcttgataga
    11041 aacaattaaa ctagtacata gtaaagatgt tggtatggga gatttgcaac cccaaaatat
    11101 aatgattacc cccgaatcaa atgttaagat tattgatttt gaggctgcta gtgctctttc
    11161 tgaagaaaat ggagcgttgc aaacaattgg atatacaaat aagaaaaata agaatcataa
    11221 ggagcgagat tggtatgcac taaagaaagt tttaagattt tgtattctgc caataggtcc
    11281 agttactgat atagaagaaa gcattaaaaa gaaacatgat atgtggatag agaatgaatt
    11341 tggtaaagat gtttatcaat atgttgtaaa tacagaaaat ctatgtgaca gatacttatc
    11401 tgacaccaaa gaaaagatat tcaagaataa ttatgacagt gaaatcaaaa aagaaatgga
    11461 catgtcaaaa gttataaatg gattgagaaa cagcatagag agtaatatgt tgcccaacag
    11521 ctcgctaatt catggcgatg tgcggcaatt tgtaatgcca tctggaaagt taaatgtact
    11581 aactggagga actggagctg cattggcatt gtacagatct ggaaacgtca acaagcaagt
    11641 tcgggattgg attgaaaatg ttttactgaa aaaattgcat gtacttaatg atgatattgg
    11701 gttatttaca ggacgagctg gtatcgcagc aacattgtat gaattggggt acatagagga
    11761 agctatgaac ttattcaata atctgtcata tgaagatatg aaagatattt cattaaggtc
    11821 aggattgtcg ggaataggtc tttcattaat tagcttatac ttggaggaag ataatgatga
    11881 ctttttggtt acttctgaaa aaattgctga tcagatagaa aatagaatta ttgaagatga
    11941 taaattatca gcaactgatt ttgcagcagt ccctataggt ttgattgatg gttggtcagg
    12001 aatatcttta ttctatgcgg cattatattc agttactaag aaagaaaaat attatgtaaa
    12061 gtcaaaagaa tacattgagt gggatttaaa acattgtaag gtagatgaag agacgaatac
    12121 tttgcaaacg tatgatgatc aaaaccctcg attactaccc tatttatcag gaggatcaat
    12181 cggaataggg gttgctattt ggtatttaaa ttatgtagga aataataatt tatttagaga
    12241 agaattagag caaataatca atttaaataa agtaagaatt gcatatagcg gtggattgtt
    12301 tgatggggtc ggtagtttct tgttaatccc gtcaatgact aaggaaaata atgaaatcag
    12361 tcagcagatt gagctggcat tgaaaaaact agaattgttt cttatccgca aagatgatca
    12421 agtattattc cctggaaact tcagttttcg tttagcagat gattactact ccggaagtgc
    12481 tggcataata ttgggcataa actctatcca gttctcaaat ccgttatatt ggttgccaat
    12541 aataaaaatt gatagtttct taaataagac taaaaaagaa ttgttgttaa acaattaaac
    12601 tctaacactt atagttgatg ataatcattg aagattggaa ttaaagcatt tatagaactt
    12661 acgaaggagg tgagaaaaga aaatgaaaga ggtgttagaa cttcaacaat ttaatgaaaa
    12721 atctgaagta gagcctgcgg catggactgt tactctaaca actatttctg ttacattatc
    12781 taccattagc aatcattgct aattgaagca taatcaaaga aagaatactt gaaaggaggt
    12841 gaaaccaaat gaaagatgta ttggaacttc aacaactcag tgaaggatct gacgtagaag
    12901 cttcaaaagg caaaggtggc ttgcttacgc taatcacaac gatagtaggc acatctacta
    12961 ttagcaataa ctgttaaggg taattaagag gggtggatga acaaatgaat gaagtactag
    13021 agttacaaca attgagtaaa ggttctgaag tagaaacagc tgggtggaca cttctgacaa
    13081 cactcatcgg tacatctact attagcaata gttgtaataa atgataaaaa ggagatgaaa
    13141 ccaaatgaaa gatgtattgg aacttcaaca actcaatgaa ggatctgacg tagaagcttc
    13201 aaaaggcaaa ggtggcttgc ttacactaat cacaacggta gttggcacat ctactattag
    13261 caataactgt ggataaaagg ccacacataa caaaaaagat tttcttacgt acatcaagtg
    13321 ctgaagtagg aacaatgggt gctcacttct aataacactc atcgtacatt tactattagc
    13381 aaagttgtaa taaatgataa atgataaaag ggagatgaaa ccaaatgaaa gatgtattgg
    13441 aacttcaaca actcaatgaa ggatctgacg tagaagcttc aaaaggcaaa ggtggcttgc
    13501 ttacgctaat cacaacggta gttggcacat ctactattag caacaactgt ggataaaagg
    13561 ccacacataa caaaaaagat tttctacgta catcaagtgc tgaagtagga acaatgggta
    13621 ggcacttcta acaacactca ttgacattta ctattagcaa agttgtaata aatgataaaa
    13681 aggaggtcaa accaaatgaa agatgtattg gaacttcaac aactcaatga aggatctgac
    13741 gtagaagctt caaaaggcaa aggtggcttg cttacactaa tcacaacgat agtaggcaca
    13801 tctactatta gcaacaactg tggataaaag accaaacaca ctaaaaaagt atgcttggtc
    13861 gttatacatt atatgaaagc ctgaacagga aaaggacccc aatccttttc ctgtttccaa
    13921 aaaaaggaac aaatttagct ttcgtataaa ttctttttac tatcccatac ttctttttta
    13981 ttgtcaatgg aaaatgaatg aagggactta gttcttcatt tatatgtaga actaaaatca
    14041 tgctaaattt ataaaatgta gaatggagga atattaatga ataatgtttt agcattacaa
    14101 caattaaata atagtgccga ggtggaaccg caagtgggac caaccataac aactattaca
    14161 gtaataccta caatggttat atccttaata agtaattatt gcgacaatca tgcttcataa
    14221 tataatgatt ttagattgac acttggctaa aaagtattgc agagaaggaa atggataact
    14281 aaatggataa agtatataaa aaacgaccgt tatataaaag aagttggttt caaacatttt
    14341 tggcattttt agtatctcag ctttatttta attttgtaga attaacggga tggggtccta
    14401 agtatagaga aatgaatgga ttcccagcaa acatagttga actagatttc tttcaaacat
    14461 atctttcatt ctatgataat ccatggttta atattattac tgttttcttg ggagttttca
    14521 ctattataca aataattaca gggataacaa aggatattcg aaattaaagc aataacttct
    14581 gatgccttat ttaatgatga aagaaaatga acactttctt aattatctta tgagtgaaga
    14641 ctgcgacact tagtcagcag tctattttat tggttctgga tcaggattac cgaattataa
    14701 ccctatacaa atatatagta ggttgctact tgctgcgttg attattttct aaatcatgag
    14761 caaatcccaa atggttcaga ttaaagttct tgcatttttt taagtaggag tttattttct
    14821 cttctcaccc tctttactcc atgtgattca taagtggtag caagcttaag tagaggtttt
    14881 ttcattctct tgagtactca gttataccac ccccaactca atttgcttaa tcaaagttta
    14941 tctcttgaat tagtttttcc gcaaatatga tattgagata cggatatggt gtagcgttaa
    15001 atatcttatc ttcaataaca ggacaattat tttgcgttgg taatatggag aactcatatg
    15061 atattctatt taggttggaa tactatttat ccaaaaagtt caaaagtaag gccactaaga
    15121 aagacgaagg tcggcgccag tgttagccac aatataaaaa ataggtgtag ataatcatcc
    15181 cacgtgaaat gttcaaaatt tactatagat tgataagaaa tgctttcgca tgcgatagtg
    15241 taaaaaaagc atggtcagtt ttttttatat tgagataaag gtatagccgt atcccctaat
    15301 gaaaggattt gatttttgtt atgacagata atttctggcg tgaattacca cggccctttt
    15361 ttgtactggc cccaatggaa gatgtgacgg atgttgtttt ccgtcatgta gtaagtgaag
    15421 caggcaggcc ggatgtattt tttacagagt ttacaaactc ggagagctat tgtcacccgg
    15481 atgggaagga tagtgtccgc ggccgtttga ccttcacgga ggatgaacag ccaatggtgg
    15541 ctcatatatg gggagacaag cctgagaact ttcgccaaat gagtattggt atggcggagc
    15601 taggatttaa gggtctagat atcaatatgg gctgtcctgt gcctaatgtg gcaggcaatg
    15661 ggaagggaag cggccttatt tgccgtcctg aagttgcagc agaattaata caagctgcaa
    15721 aagcaggggg attgcctgta agtgtgaaga caaggcttgg ttacacgaat gtggacgaat
    15781 ggcgcgattg gctgacacac gtattgaagc aggacattgc taatctctct attcatcttc
    15841 gtacaagagc ggaaatgagt aaagtggatg cgcattggga actcatcccg gagattaaga
    15901 aacttcgtga cgaggtggcg ccagatactc ttttgacgat caatggggat atccctgacc
    15961 gtcaaactgg cttgaaactc gctcaagaat acggtgttga tggaattatg attgggcgtg
    16021 gtatttttac aaatccattt gcctttgaaa aggagccgaa agagcatagc agcaaggaat
    16081 tgcttgatct cttaaggctg cacctggatc ttcatgataa atattcagca ttagaagcgc
    16141 gtccgtacaa gcctcttcct cgctttttca agatttatct ccgcggattc cgaggggcga
    16201 gtgaattaag aaatcaatgc atgaacacaa agtcaacgga tgaagtgcgg gcattgctcg
    16261 atgactttga gagaaagtat ctttcaggga tagagtaaca gcagtgcttg aaaatttaat
    16321 ccaattctaa tcctggatct cggtaaaata aacaattccg atttccgggt ttttttgtac
    16381 gcagctttta ctcacctgtc ttttctctaa tttattgtaa gaaaataatg gtatatttag
    16441 tggagatatc ttataaaggg ggagagaaaa atgaaacgac tatgcatcat cccctgcggc
    16501 aagaaaaaaa tctgggatgt caagcctgat gccgggccgg taagagcaga ggacgcttat
    16561 ctcagcccgt ttcatcaggc gtgcgagcgg tatgcgaaag catttttcga tgagtgggtg
    16621 attttgtcag cgaagcacgg ctttcttcgc cctaatgata tcgtatcagg aaattacgat
    16681 gtgacttttg gcaccggtca tgcggaaatc atgacatcag aggagctgcg ccgccaattt
    16741 tgcgaaaaag gcttttccga catcgaagag cttgtcatgc ttggcgggaa aaaatatcga
    16801 agcgtcctaa acgccgtcat cggcgagcat caatatatca attggcccct gtcatcatac
    16861 aaaggcattg gctacatgct tcaagcactg aaccgggcgg ttgaagacaa gcatgaactg
    16921 tagcacgtac atatcaagaa aagagtgtga acatgaaaaa acttgtgttt ggcttgcttg
    16981 ttattgcggt attcggatac gggctatata tctaccatat atggttcgct gatccatttt
    17041 cgaaaaatgc cgcagagcag aagcttgtct cttatgtgaa acaaacctat cctgaaaaaa
    17101 aacgaagatc acgaatgggg tatataacgc taaaacctct gaatatgtat tccaagcaaa
    17161 catccaatct catcgctacc caatgtgtac gaagggattt ctccatccta aagtaacgtg
    17221 cgatggaatt gaagaagcat ataccgaatc agtagcaaag catgtaaatg aagtagcatc
    17281 gaaggcaatt gaagcagatc tgaaaaaagc ggttccgcaa tattcaattg attttctttc
    17341 aaaagcagcg attcagtcaa acgatgcaga ggaactggga agttaaaaaa tttccaagga
    17401 aataaatacg tcgaaccttg tcaaaggccg ggtgatatcc ggtctttttt gcatctgtaa
    17461 attgatacaa atgaatcagt atgagacaaa acgagacacc cgtctcaaac tgtctccggt
    17521 gtgaagacga gaagactgat tttacgggct ccaaagattg gcacacttct tgcatttatt
    17581 atcgtgaacc ctaaatagaa ggaggcacac acaatggaac tgttaaaacg agaaggcttg
    17641 tcattaactg aggaaaaagc gctgtggatg taccaaaaga tgctggaaat caggggcttt
    17701 gaggacaaag tgcatgaact gttcgcagag ggagtgcttc ccggattcgt ccatttgtat
    17761 gctggtgaag aagcggtagc tgtaggcgtg tgcgctcact tagatgatgg cgacagtatt
    17821 acaagcacac acagagggca tggccattgt atcgccaagg gctgtgatct gaacggcatg
    17881 atggctgaaa ttttcgggaa agcgaccggg ctttgtaaag gcaaaggcgg atcgatgcac
    17941 attgctgatc tcgataaagg catgttgggg gcaaatggaa tcgtcggggg cgggtttacg
    18001 ctcgcatgcg ggtcagcgct cacggctaaa tataaacaga ctaaaaatgt aagcgtttgc
    18061 ttttttggag acggagcaaa taaccaagga accttccatg aaggcctcaa cttagcggct
    18121 gtatggaacc ttccagttgt gtttattgct gaaaacaatg gctacggcga agccacgcca
    18181 tttgagtacg cgtcagcctg tgattcaatc gctgatcggg cagctgccta taacatgccg
    18241 ggagtaaccg tggacggaaa agatatttta gcagtttacc aggcagcgga ggaagcaatt
    18301 gaacgagcaa gaaacggcgg aggcccgtct ttaattgaat gcatgaccta ccgaaactac
    18361 ggccatttcg aaggagatgc ccaaacctat aaaacaaagg atgaaagagt tgagcacctt
    18421 gaagaaaagg acgccattca aggctttaaa aactatctgt taaaagagac ggatgaaaaa
    18481 aaactggcag acattgaaca aagcgtgaat gaagcaattg aaaaagcggt ctccttcagc
    18541 caagacagcc catatccgaa agaatcagag ctgctgacag atgtatatgt ctcatatgaa
    18601 aaaggaggaa tgtaagatgg caagagtcat aagcatgtca gacgcgatca atgaggcgat
    18661 gaaacttgcg atgagaaggg atgaaaatgt gctgttgatc ggtgaggatg tagccggagg
    18721 agcggcagtc gatcatttgc aggacgatga agcatggggc ggcgtattag gcgtcaccaa
    18781 agggctcgtt caggaatttg gacggagcag ggtgctggat acgcctattt ctgaagcggg
    18841 ctatatgggc gccgctatgg ctgcggcatc cacagggctg agaccgattg cggagctgat
    18901 gtttaacgac ttcatcggca cgtgctttga ccaggtcatc aaccaagggg caaaattccg
    18961 ctatatgttc ggcggaaaag cgcaagtgcc aattaccgtc cgcaccacat acggagcggg
    19021 tttccgggct gcggcacagc actcccaggc gctgtacggc cttttcacaa gcattccggg
    19081 gttgaagacg gttgttccat cgaatccgta tgacgccaaa ggcctgctgc ttgcggcaat
    19141 cgaagacaac gatccggtgt tcttttttga agataaaacg tcctacaaca tgaaaggcga
    19201 agtgccggaa gagtattata caatcccgct tggaaaagcg gacatcaaac gcgagggcag
    19261 cgacatcacg ctgtttgcga tcggcaagca ggtcaatacc gcactcgaag cggcagcaca
    19321 attatcagaa aaaggcatcg aagccgaggt actcgatccc cgcagtctgt ctcctctgga
    19381 tgaggacgcg attttcacat cgttagaaaa aacaaaccgg ctgatcatcg tggacgaagc
    19441 caacccgcga tgcagcatag cgacagatat tgccgcgatt gtggctgaca aaggctttga
    19501 tctgctagat gcgccgatta agcggattac agcgccgcac acacctgtgc cgttttcgcc
    19561 agtgcttgaa gatcaatatt tgccgacacc agataaaatc gtcagcgtca cgcttgaatt
    19621 gcttggcgag ccggcagtga attaaagggg ggacacatat ggcggtcaaa gtagtgatgc
    19681 caaagttggg aatggccatg aaacaaggag aagtatcaat ttggaacaaa aaagtgggag
    19741 atccggttga aaaaggagaa agcatcgcca gcattcagtc ggagaaaatt gaaatggaaa
    19801 ttgaagcgcc agaaaagggc acgctcattg atatcaaggt gaaagaaggg gaagaggttc
    19861 cgcccggtac ggccatctgc tacatcgggg atgccgatga atcggtgcag gaagaaacgg
    19921 aagagccagc cgctgaagca agcaggcaag cagatcccca gcctcctaaa catgaaaaca
    19981 aacccgcaaa cactaaaaaa gatagactga aaatctctcc agtcgccaga aaaatagcgg
    20041 aaaaagcagg gttagacctg aaaaatctga agggcacggg accgggtgga cgaatcgtga
    20101 aggatgatgt cacaaaggcg ctttctgaac aaaaaagaga acaggctgag ccagtttccg
    20161 accaaaaggc gcaggaaacg ccggttacag gcatgagaaa agtgatcgcg tccagaatgc
    20221 aggaaagctt ggcaaacagc gcccagctga cgattacaat gaaggctgat atcactaagc
    20281 tggcagcgct tcaaaaacag ctttcgccga cagcagagga acggcacggt acgaaattaa
    20341 cgatgactca ttttgtctca agagctgcgg tgctcgctct ccaatcacat cctatgctga
    20401 acagcttcta caaaaatgag cgcattatca cacatcctca tgttcatctt ggaatggctg
    20461 ttgctcttga aaaagggttg gttgtgcctg tgatccgcca tgctgaaaag aaatcgctga
    20521 ttgaactggc tcaatccatc tcggaaaatg ccaaaaaagc acgagaggga tgggcgggaa
    20581 gcgaagaact gcaaggctca acattctcca ttacaaacct tggcgctttt ggagtggagc
    20641 atttcacgcc gatattaaat ccgccggaaa caggcattct cggcatcgga gcaagctatg
    20701 atacgccggt gtatctaggg gaggaaattg tcagaagcat ggtcctgccg ctcagcctga
    20761 catttgatca cagagtctgt gacggcgctc cggccgctac ctttctgaag gcgattaaaa
    20821 catatttgga agaaccggca gcattaattt tataggaaaa gcaggtgaaa acgacatgac
    20881 actagccatt atcggagggg gaccggctgg ctatgccgct gcagtctccg cggcacagca
    20941 ggggaaaaag gtgctgctca ttgacaaagg ctcgcttgga ggaacctgtc tgaatgaagg
    21001 ctgcattccg acgaagtctt tgttagaaag cgcaaacgta cttgataaaa tcaaacatgc
    21061 cgggcgcttt ggaattgaac ttccgcctgg tgcaatctcg gttgattgga acaagatgca
    21121 gagcaggaaa cagcaggttg tcagccagct tgtccaaggc gtacagtact taatgaagaa
    21181 aaatcaaata caggtcgtaa agggagaggc ttcctttctt tctgacaaga agctcttgat
    21241 caaaggggag aacggaaaag aaatcagaga ggcggaacaa atattgatcg caaccggatc
    21301 agagccgatc gagctgccct ttgccccgtt tgacggcgaa tgggtgattg acagcaaaga
    21361 cgcactcgcc ctttcagaca ttcccgcttc gcttgtaatt gtcggcggcg gtgtgatcgg
    21421 ctgcgagtat gccggattgt tcgccagact tggaacgaag gtgacgatca ttgaaacagc
    21481 cggccagctg attccggcag aggatgagga tatcgcccgt cactttcagg aaaagcttga
    21541 ggaagacgga gttgaagttc atacctcctc ccggttagag cgtgttgatc cagcagccaa
    21601 aacggcgata tggaaaagcg gacagcgtga gtttaagacg aaggccgatt atgtgctggt
    21661 ggcgattgga agaaaacctc gtctggatgg attacagctt gagcaggcgg gaattgattt
    21721 ttcccataaa ggtattcccg taaatgagca gatgcagacc aatgtgtctc atatctacgc
    21781 atgcggggac gcgatcggtg gcattcagct ggctcatgcc gctttccatg aagggatcat
    21841 cgcagcttca cacgcttcag gacggaacgt caaaatgaac gaaaaaaatg tgccccgatg
    21901 tatttataca tccccggaaa ttgcttgtat cggattgaca gaaaaacagg cgaaacacgt
    21961 ttacggagat gtacagattg gtgaatttcc tttttccgca aacgggaagg cgctcatcaa
    22021 acaccaagca gaaggaaagg tcaaaattgt ggttgagcca gagttcagtg aaatcgtcgg
    22081 agtctcaatg atcggaccgg atgtgaccga gctcatcggc caggcggctg ccatcatgaa
    22141 cggtgaaatg acggcggata tggcagagca ttttatcgcg gctcatccga cactctcgga
    22201 aacgctgcac gaagcattgt taagcacaat tgggcttgcg gtgcatgcat aacaagaaaa
    22261 gctggcgaat gcgccagctt ttttattgtt gaaagcgctt tacttttccc ctacaataga
    22321 tgaaaacggc gtgtaaggga ggaacgatca aggaatgaat tcgatcccga acgatttgca
    22381 aacctggaaa cgttttgtga aggacggcgt gctggacgaa gcccgaataa gaaaaaggat
    22441 agccgagtcc tggcatcgct gcagaaaggc tgaggttaac ccctatttgg aaaaaggccc
    22501 gaaggttttg cagcaaacgg agctggatca gcagtcaaac aaacattcat tctttctgtc
    22561 gaccgcaatg ccttacctgg aaaaattgct gcctgcaa
//
