LOCUS       NZ_JALAKZ010000010     12957 bp    DNA     linear   CON 23-JAN-2024
DEFINITION  Bacillus inaquosorum strain N9C1 contig_0000010, whole genome
            shotgun sequence.
ACCESSION   NZ_JALAKZ010000010
VERSION     NZ_JALAKZ010000010.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus inaquosorum
  ORGANISM  Bacillus inaquosorum
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 434537)
  AUTHORS   Dunlap,C.
  TITLE     Crop Bioprotection Bacillus Genome Sequencing
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 434537)
  AUTHORS   Dunlap,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-FEB-2022) CBP, USDA-ARS-NCAUR, 1815 N. University St.,
            Peoria, IL 61604, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC NGS Cell v. 21
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 455.1098425649713x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/23/2024 03:19:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,308
            CDSs (total)                      :: 4,217
            Genes (coding)                    :: 4,075
            CDSs (with protein)               :: 4,075
            Genes (RNA)                       :: 91
            rRNAs                             :: 1, 5, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 4 (16S)
            tRNAs                             :: 79
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 86 of 142
            Pseudo Genes (incomplete)         :: 82 of 142
            Pseudo Genes (internal stop)      :: 25 of 142
            Pseudo Genes (multiple problems)  :: 41 of 142
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:33:50
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 12957
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JALAKZ010000010.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..12957
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="CDPS"
                     /region_number="1"
                     /rules="CDPS"
                     /tool="antismash"
     cand_cluster    1..12957
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="CDPS"
                     /kind="single"
                     /product="CDPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..12957
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[2210:2957](+)"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2211..2957
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
     gene            complement(39..1250)
                     /locus_tag="MOB76_RS11090"
                     /old_locus_tag="MOB76_11075"
     CDS             complement(39..1250)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391389.1"
                     /locus_tag="MOB76_RS11090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB76_11075"
                     /product="MFS transporter"
                     /protein_id="WP_268292528.1"
                     /transl_table=11
                     /translation="MAQMKSKAVLILYIVCFSAFFASLSQNIYSPIIPIIKESFHVSAA
                     MVNLSVSVFMIVTAIMQIILGTIIDFKGARFVLIAGILATTAASIGCAVTTDFTLFLIF
                     RMIQAAGSAALPLIAATTIGQLFTGSERGSAMGTYQMLLSAAPAVAPVLGGFIGGAAGY
                     EGIFWMLTAISVVMLVANSMIFPKDSPAGSKQQTKGNVFTHYKSIFTNRTGNVILALSF
                     VLFFIYFAVIVYLPILLTEHYHIDVSIAGLLYLPLALSTIAGTFLFKRIQAKISLNTLF
                     IGSNAVAACSIMLFAVTHSVSLVLMALTLALFGISMGVIPPLYSTMITNEFEHNRGSAI
                     GIFNFIRYTGMAAGPMISAYLLTMMPSAMSFGLLGLVFAALSFCLLPQMYPPQKRVKQK
                     KHHM"
     gene            complement(1272..1781)
                     /gene="pchR"
                     /locus_tag="MOB76_RS11095"
                     /old_locus_tag="MOB76_11080"
     CDS             complement(1272..1781)
                     /codon_start=1
                     /gene="pchR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391388.1"
                     /locus_tag="MOB76_RS11095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB76_11080"
                     /product="pulcherriminic acid biosynthesis transcriptional
                     regulator PchR"
                     /protein_id="WP_003235414.1"
                     /transl_table=11
                     /translation="MSDLTKQMIYDIYVRLLHLNEQKANTSLQQFFKEAAEEDVIDIPK
                     NMTSIHVIDCIGKHEPINNAGIAKKMNLSKANVTKISTKLITEEFINSYQLTDNKKEVY
                     FKLTRKGKRIFDLHEKLHKKKELAFYQFLDSFSQDEQNAVLKFLEQLTSTLEAEQTDGT
                     PDKPVK"
     gene            2211..2957
                     /gene="pchC"
                     /locus_tag="MOB76_RS11100"
                     /old_locus_tag="MOB76_11085"
     CDS             2211..2957
                     /EC_number="2.3.2.22"
                     /codon_start=1
                     /gene="pchC"
                     /gene_functions="biosynthetic (rule-based-clusters) CDPS:
                     CDPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391387.1"
                     /locus_tag="MOB76_RS11100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB76_11085"
                     /product="cyclo(L-leucyl-L-leucyl) synthase"
                     /protein_id="WP_268292529.1"
                     /sec_met_domain="CDPS (E-value: 6.5e-83, bitscore: 272.4,
                     seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEMVTERKPVDFTAESLTQNCREIFERRRHVLVGISPFNSRFSE
                     DYIYRLIGWATAEFKNVSVLLAGHEAANLLEALGTPRGKAERKVRKEVSRNRRFAERAL
                     AAHGGDSKAIHTFSDFAENNAYQLLRQEVEHAFFEQPHFRHACLDMSREAMIGRARGIS
                     LMMEEVSEDMLNLAVEYVIAELPFFIGAPDILEVDETLLAYHRPWKLGEKISNHEFSIR
                     MRPNQGYLIVQETAQMLSETRITSEG"
     gene            2972..4192
                     /gene="cypX"
                     /locus_tag="MOB76_RS11105"
                     /old_locus_tag="MOB76_11090"
     CDS             2972..4192
                     /EC_number="1.14.15.13"
                     /codon_start=1
                     /gene="cypX"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003235412.1"
                     /locus_tag="MOB76_RS11105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB76_11090"
                     /product="pulcherriminic acid synthase"
                     /protein_id="WP_268292530.1"
                     /sec_met_domain="p450 (E-value: 1.7e-38, bitscore: 127.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQSIKLFSVLSDQFQENPYAYFSRLREEDPVHYEESIDSYFISR
                     YHDVRYILQHPDIFTTKSLVERAEPVMRGPVLAQMHGKEHSAKRRIVVRSFVGDALDHL
                     SPFIKQNAENLLDPYLEKGRIDLVNDFGKTFAVCVTMDMLGLDKRDHEKIAEWHSGVAD
                     FITSIFQTPEARAHSLWCSEQLSDYLMPVIEERRVNPGSDLISILCTSEYEGMAMSDKD
                     ILALILNVLLAATEPADKTLALMIYHLLNNPEQMNDVLADRSLVPRVIAETLRYKPPVQ
                     LIPRQLSQDTVVGGMEIKKDTIVFCMIGAANRDPEAFEHPDVFNIHREDLGIKSAFSGA
                     ARHLAFGSGIHNCVGAAFAKTEIEIVANIVLDKMRNIRLEEGFRYAESGLYTRGPVSLH
                     IAFDRAQ"
     gene            complement(4227..4700)
                     /locus_tag="MOB76_RS11110"
                     /old_locus_tag="MOB76_11095"
     CDS             complement(4227..4700)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391385.1"
                     /locus_tag="MOB76_RS11110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB76_11095"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_232918699.1"
                     /transl_table=11
                     /translation="MDNSIHDELFQAIQQFALKRDKRVWQKVHIPSRGMSSTHLEHLKK
                     DWTLTQLHIVSCIHTSQNVNNSSLASRLHISKAAVSKAVQALLNHNIITVTKKPGNKKE
                     IFYTLTESGRELAALHEQLHEKAKEQYKQLFNEFSIDDLKTVTAFLNLWVKHM"
     gene            4865..8734
                     /locus_tag="MOB76_RS11115"
                     /old_locus_tag="MOB76_11100"
     CDS             4865..8734
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391384.1"
                     /locus_tag="MOB76_RS11115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB76_11100"
                     /product="metallophosphoesterase"
                     /protein_id="WP_268292531.1"
                     /transl_table=11
                     /translation="MRKYTVIASLFLSFLSVLSGGHHESKAFPVIKQEPFQTPHYIPLL
                     ENPPQIDVKAEMKSNLMIEAQVRDNEYQAFSAFLFYKQSNELGYKMVPMDPTPGAIHKF
                     LAQIPKRLIWNSELEYYIVISNGKQRVESETKKLKLEGYQADLAHIPELLITELAVDTK
                     NTGRADGYEFIEIYNTTDRTIDFKDYHIRYRYPKEGPDSDLIWRPDERITIPSGETFVV
                     WLKPVGHPELTAEDFNRYYQTQLTEGKNLAVLEETEGMANTRPRSVVISTNTGKDISVA
                     HYRKHALRRLSSVLYKYPLDGTAELLNISIGEKNPSPGTVLQAQVPEQKRKIKLDKEKP
                     VIEDLTDRKPVRPAESIELRADIRDRSLVKTAAFYYRTDENKPFKRILTEKDRNDNLYH
                     YIVYSPELIGKDQLEYYVAAGDGINEARTPVKMIDIKQTSKSHGLRMNIENRDTLSGTQ
                     FLKATTDGRTNSIKLWIDGKKQVTEPAMEKEVYFAFDTRKTNLYFKNAVTMEGKVLKVF
                     DDTTNKYRTYSVPLPELLLRKGKQLQRITIRSGSKVSPFDTAENRDDFLVKNARLVLSD
                     GTVIRDQRVSPEKELFIGDNQRSNKSWQFQFNLPDGLFTSQLLKWDTSKLSEGAHHIQA
                     SDGKENVSLVVRVDNSGPHIEPNITEGQTYKGNLILQADMYDKWSKIEEAEASLDGESI
                     TLPYHTSSSELLPGKHSLKITATDLAGNKTVIERTFKTEREHPDQPEIIDSEADTHRAK
                     LSVRVKDPTDDPMDVAFYRGFQYTARNNVKIFKHASLTEPPKSFVPENETPFTNKELER
                     VSAVDGKTVSTEKKELFPYHRFEVTVDPSVDENDLAEAVWKGSSLPGRKVTMYAWNYRT
                     NEWQPVDSFVAKDHKPFTLKASVIASDFVRKSKMNVIVQDEIPPAKDMYTFAWMSDTQY
                     YAESYPHIFDKQTAWIKSNQKQLNIKYVFHTGDIVDDSADIRQWKNADRSMSVLDKSGI
                     PYGVLAGNHDVGHKDGSYRAFGKYFGSHRFDKKLHYGGSYKNNRGHYDLISSNGNDYIM
                     LYMGWGITDEDIAWMNQVLKKHPDRMAVLAFHEYLLVSGNRSPIGEKIFKKVVKPNPNV
                     VMVLSGHYHSAMRKTDELDDDGDGKPDRLVHQMLADYQGGPEGGQGYLRLLQFDQANDM
                     VHVSTYSPHLQDKNYYDTDTYGNKDEFSLSLDLKPRVKKVETDYFECNVYTNEELGKRE
                     QVKSGDTAEFRWDDLEPHSVYYWYTIVEDSFNGKTKSPIWKFKTKKETYRPSPDQFDFR
                     HVSNP"
     gene            complement(8753..9484)
                     /gene="nagR"
                     /gene_synonym="yvoA"
                     /locus_tag="MOB76_RS11120"
                     /old_locus_tag="MOB76_11105"
     CDS             complement(8753..9484)
                     /codon_start=1
                     /gene="nagR"
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /gene_synonym="yvoA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391383.1"
                     /locus_tag="MOB76_RS11120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB76_11105"
                     /product="N-acetylglucosamine utilization transcriptional
                     regulator NagR"
                     /protein_id="WP_268275947.1"
                     /transl_table=11
                     /translation="MNIDKQSPIPMYYQIMEQLKAQIKSGELQPDMPLPSEREYAEQFG
                     ISRMTVRQALSNLVNEGFLYRLKGRGTFVSKPKMEQALQGLTSFTEDMKSRGMTPGSRL
                     IDYQLIESTEELAALLGCGHPSPIHKITRVRLANDIPMAIESSHIPFELAGELNESHFQ
                     SSIYEHIEKYNSIPISRAKQELEPSAATSKEASILGIQKGAPVLLIKRTTYLQNGTAFE
                     HAKSVYRGDRYTFVHYMDRLS"
     gene            complement(9502..10230)
                     /gene="nagB"
                     /locus_tag="MOB76_RS11125"
                     /old_locus_tag="MOB76_11110"
     CDS             complement(9502..10230)
                     /EC_number="3.5.99.6"
                     /GO_function="GO:0004342 - glucosamine-6-phosphate
                     deaminase activity [Evidence IEA]"
                     /GO_process="GO:0006046 - N-acetylglucosamine catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="nagB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391382.1"
                     /locus_tag="MOB76_RS11125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB76_11110"
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="WP_268275536.1"
                     /transl_table=11
                     /translation="MKVVECQTYEELSQKAARIAADTIKEKPDAVLGLATGGTPEGTYR
                     ELIRLHQTENLSFKNVTTVNLDEYAGLSSDDPNSYHYYMNSRFFQHIDSQPNRHFIPNG
                     NADDLEAECRRYEQLVESIGGTDIQLLGIGRNGHIGFNEPGTPFKSRTHVVTLNEQTRQ
                     ANARYFSSIDSVPKKALTMGIQTILSSKRILLLISGKSKAEAARKLLEGDVSEDFPASA
                     LHLHPDVTILIDREAAALRP"
     gene            complement(10227..11417)
                     /gene="nagA"
                     /locus_tag="MOB76_RS11130"
                     /old_locus_tag="MOB76_11115"
     CDS             complement(10227..11417)
                     /EC_number="3.5.1.25"
                     /GO_function="GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA]"
                     /GO_process="GO:0006040 - amino sugar metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="nagA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391381.1"
                     /locus_tag="MOB76_RS11130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB76_11115"
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="WP_268292532.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 3.6e-42, bitscore:
                     139.5, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKSLLIKGIAIVTENEVIKNGYVGINGGKISTVSTERPKESYSK
                     EIQAPADSVLLPGMIDIHIHGGYGADTMDASFSALDTMSSRLPEEGTTSFLATTITQEH
                     GHISQALVNARDWKAAEESSLLGAELLGIHLEGPFVSPKRAGAQPKECIRPSDVALFKK
                     WQQEAGGLIKIVTLAPEEDQHFELIHYLKDESIIASMGHTDADSALLSEAAKAGASHMT
                     HLYNAMSPFHHREPGVIGTALAHDGFVTELIADGIHSHPLAAKLAFLAKGSSKLILITD
                     SMRAKGLKDGVYEFGGQSVTVRGKTALLSDGTLAGSILKMNEGARHMREFTNCSWTDIA
                     NITSANAAKQLGIFDRKGSVTEGKDADLVIVSSDCEVILTICRGNIAFISKEADQI"
     misc_feature    complement(11472..11487)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.26"
                     /tool="antismash"
     gene            11599..12531
                     /gene="hprK"
                     /locus_tag="MOB76_RS11135"
                     /old_locus_tag="MOB76_11120"
     CDS             11599..12531
                     /GO_function="GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /gene="hprK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391380.1"
                     /locus_tag="MOB76_RS11135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB76_11120"
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="WP_003235406.1"
                     /transl_table=11
                     /translation="MAKVRTKDVMEQFNLELISGEEGVNRPITMSDLSRPGIEIAGYFT
                     YYPRERVQLLGKTELSFFEQLPEEDKKQRMDSLCTDVTPAIILSRDMPIPQELIDASEK
                     NGVPVLRSPLKTTRLSSRLTNFLESRLAPTTAIHGVLVDIYGVGVLITGKSGVGKSETA
                     LELVKRGHRLVADDCVEIRQEDQDTLVGNAPELIEHLLEIRGLGIINVMTLFGAGAVRS
                     NKRITIVMNLELWEQGKQYDRLGLEEETMKIIDTEITKLTIPVRPGRNLAVIIEVAAMN
                     FRLKRMGLNAAEQFTNKLADVIEDGEQDE"
ORIGIN
        1 tcaaaaacgg gggtcagtcc cacagaaggc agcttttttt acatatggtg ttttttttgt
       61 ttaacgcgct tctgcggcgg atacatttga ggcaaaaggc aaaagctcaa tgcggcaaat
      121 acaaggccta agaggccaaa ggacatggca gacggcatca tggtgagcag ataggcagat
      181 atcatcggac ctgccgccat gcctgtgtat ctgataaagt tgaaaattcc gattgcactc
      241 cctctgttgt gttcaaattc attggtgatc attgtggagt acaagggagg aatgaccccc
      301 atcgagatgc caaacagtgc cagtgtaaga gccatgagaa cgagagaaac ggaatgtgta
      361 acggcgaaca acatgatact gcaggccgcg accgcattgc tgccgataaa caatgtgttc
      421 agcgagattt ttgcctgtat tcttttaaac aaaaacgtac ctgcgatcgt acttagcgcc
      481 agtggcaaat ataacaatcc tgctatgctc acatcaatat gataatgctc cgtcagtaat
      541 atcgggaggt agacgatcac cgcaaaataa atgaaaaaga ggacaaaact taaggccaaa
      601 atgacgtttc ctgttcgatt tgtaaatatt gatttgtaat gagtgaacac attgcctttg
      661 gtttgctgct tagatcctgc gggagagtcc ttaggaaaaa tcatgctgtt tgcaaccagc
      721 ataacgacag agatggccgt gagcatccag aagatccctt cgtatccggc tgctccgcct
      781 atgaatccgc cgaggacagg ggcgacagcc ggcgcggcgg aaaggagcat ttgatacgtt
      841 cccatcgcac tcccgcgttc actgcctgta aaaagctgtc cgatcgttgt ggcagcaatg
      901 agaggcagtg ctgcggaccc ggcagcctgt atcattctga atatcagaaa caaagtaaag
      961 tcagtggtca ccgcacagcc gatgctggct gctgtcgttg ccagaattcc ggcaatcaag
     1021 acaaaccgcg cgcctttaaa atcgataatg gtccctaata taatttgcat aatcgctgtc
     1081 acaatcataa agacggagac tgacagattc accattgctg cagaaacatg gaacgattct
     1141 ttaatgatcg ggattatagg tgaataaatg ttttggctta aagatgcaaa aaatgcgctg
     1201 aagcaaacaa tgtataagat caataccgct tttgatttca tttgagccat aaagaataca
     1261 ccgccttttg tttactttac aggtttgtcc ggagtcccat cggtttgttc tgcttcaagt
     1321 gtagacgtca gctgctctaa aaatttcaat acagcatttt gctcatcttg tgaaaacgaa
     1381 tcgaggaatt ggtaaaaggc cagctccttt tttttatgca gtttctcatg caagtcgaaa
     1441 atccgtttgc ctttacgggt taatttgaaa tacacttctt ttttgttatc tgtcagctga
     1501 tagctgttaa tgaattcttc cgtgatcaat tttgtgctga ttttcgttac attcgctttt
     1561 gataagttca ttttttttgc gatccccgca ttgttaatgg gctcatgctt gccgatgcag
     1621 tcaatgacat gaatgcttgt catgttttta gggatatcga tcacatcctc ttctgcggcc
     1681 tccttaaaaa attgctgaag tgaagtgttc gctttttgtt cattaaggtg cagcagtctc
     1741 acatatatgt cgtatatcat ctgctttgtc aaatcagaca taggctacct tctttctgag
     1801 gaataatagt ttacgatgaa acaataaata aaattgttta ccggtgaacg atttaatttt
     1861 atcttttctt actttcgttg tcaattgctg gagtttaaac tttatccggt gttatgtcat
     1921 gctgaacagg agtgtaaaaa gtgtgtgaaa aatgtgacat ttacatttat ttcaaaaaaa
     1981 taggtctatt catattgacg ggtggaacga taagggataa aatgactaat gtttactagt
     2041 aaacatttat catgatatga ataatgaaaa agaagtttta aatcttaaaa taattcactt
     2101 agaaacttta agtgctgcct gccattcgtc ttgttcagtt gtgccagtta ttctatctca
     2161 tttttgaggg tgatgactta aagcgggata agtttttaga ggtgaatgag atgaccgaaa
     2221 tggtgacgga aagaaagcct gtagatttta ctgctgagtc actgacacaa aactgcagag
     2281 aaatatttga acggcgccgg catgttttgg tggggatcag cccatttaat agcaggtttt
     2341 ctgaggatta tatttacaga ttgattggat gggcaacggc tgaatttaaa aacgtttccg
     2401 ttttgcttgc ggggcatgag gcggctaatc ttcttgaagc gctcggaact cccagaggca
     2461 aagctgagcg aaaagtaaga aaagaggtat cacgaaacag aagatttgca gaaagggctc
     2521 ttgcggctca tggcggggac tcaaaggcga ttcacacatt ttctgatttc gcggaaaaca
     2581 atgcctatca gctgttgaga caagaagttg aacatgcgtt ttttgagcag cctcattttc
     2641 ggcatgcttg tttggacatg tctcgtgaag cgatgatcgg gcgtgcacgc ggcatcagtt
     2701 tgatgatgga agaagtcagt gaggatatgc tgaatttagc tgtggaatat gtcattgctg
     2761 agctgccgtt ttttatcgga gctccggata ttcttgaggt ggatgagacg ctccttgctt
     2821 atcatcgtcc gtggaagctc ggtgagaaaa tcagtaacca tgaattttct attcgtatgc
     2881 ggcctaatca agggtatctc attgtgcagg aaacggcgca gatgctttct gaaacacgga
     2941 tcacatctga aggatgatag ggggagtaaa catgaatcaa tcaattaagt tgtttagtgt
     3001 gctttctgat caatttcaag aaaatccata tgcttatttt tcacggctgc gggaggaaga
     3061 tcctgttcat tatgaagagt cgatagacag ttattttatc agccgctatc acgatgtccg
     3121 ctatatcctt cagcatccgg atatttttac gacaaaatca cttgttgagc gtgctgaacc
     3181 ggtcatgcgc ggccctgtgc tggcccaaat gcatgggaaa gaacactccg caaaaagaag
     3241 aattgtagtg agaagctttg tcggggacgc attggatcat ctgtctccat tcattaagca
     3301 aaatgcagaa aacttattag atccttatct agaaaaaggg agaatcgatc tcgtcaatga
     3361 ttttggaaag acgtttgcgg tgtgtgtcac gatggacatg ctcgggctgg ataaaagaga
     3421 tcatgaaaaa atcgctgagt ggcacagcgg agttgccgat tttattacga gtatctttca
     3481 gactcctgaa gcgcgggcgc attctttatg gtgcagcgaa cagctttccg attacttgat
     3541 gccggtcatc gaggaacgcc gcgtcaatcc gggatcagat ttaatttcca tcctgtgtac
     3601 gtctgaatat gaaggcatgg cgatgtcgga caaggatata ttggcactga ttctcaatgt
     3661 gctgttagcc gcaacggaac cggcagataa gacactggcg ctgatgatat atcatttgct
     3721 caacaatccc gagcagatga atgatgtttt ggctgaccgt tcgttggtgc cgagagtcat
     3781 tgcggagacg ttgcgttata aaccgccggt tcagctgatt ccgcggcagc tgtcccaaga
     3841 tacggtggtc ggcggtatgg aaatcaaaaa agatacgatt gttttttgta tgatcggagc
     3901 agctaaccgg gacccggaag cgtttgaaca tcctgacgtg tttaatattc atcgggaaga
     3961 tctcggcatc aagagcgctt ttagcggcgc agcccggcat ctcgctttcg gatctggcat
     4021 ccataactgt gtaggagcag cttttgccaa aaccgaaatc gaaattgtag ccaatattgt
     4081 gctggataag atgcggaata tcaggttaga ggaaggtttt cgttatgctg agtccggtct
     4141 gtatacacgc ggacccgtct cacttcatat tgcgtttgac agggctcaat aagattgaaa
     4201 ggtctctccc atcgggtgag gcttttttac atatgtttga cccacaagtt taaaaacgca
     4261 gtcaccgttt ttaaatcatc aattgaaaat tcattgaaga gctgtttgta ttgctccttt
     4321 gctttttcat gaagctgttc atgtaatgcc gccagttctc tgccgctttc agttaacgta
     4381 taaaaaattt cttttttgtt gccgggcttt tttgtcactg tgatgatatt gtgattcaac
     4441 aaagcttgaa ctgcttttga aacagctgct tttgagatgt gtaagcggga tgccaaggag
     4501 ctgttgttca cattttggct ggtatgtata caggaaacaa tgtgaagctg ggtcaatgtc
     4561 cagtcttttt tgaggtgttc gagatgtgtt gaggacatgc cgcgggatgg tatgtgcacc
     4621 ttttgccaga cgcgtttatc cctttttaat gcgaattgtt gtatagcttg aaataattca
     4681 tcatgaatac tgttgtccat caatctgcct ctctgattta attgttaact ggttaactat
     4741 cttcagttta ctgggtaata gtggaatttt caagaggcag acgctttttt gttctttttg
     4801 cacaaaaata aactcataag ctttcctatt cagacgcaaa atacgtgaaa agggaggtgt
     4861 tttgatgagg aaatacacag ttatcgcttc tttgttcttg tcttttcttt cagttttgtc
     4921 tggcggccat catgaatcga aagctttccc tgttataaag caggaaccat tccaaacgcc
     4981 tcattacata cccttgcttg aaaatcctcc tcaaatcgat gtgaaagctg aaatgaaaag
     5041 caatctgatg attgaggctc aagtgcgtga caatgagtat caagcatttt ctgcctttct
     5101 tttttataaa caaagtaatg agctgggcta caaaatggtg ccgatggacc cgacacccgg
     5161 agcgattcac aagtttttgg cgcaaattcc gaaacgattg atttggaaca gcgagcttga
     5221 gtattacatt gtgatttcca atgggaagca gcgggtcgag tcggagacga agaaactgaa
     5281 gcttgaagga tatcaggctg atctcgccca tattccggag cttctgatca cagagctagc
     5341 ggttgatacg aagaacacgg gacgtgcaga cggttatgaa tttattgaga tttataatac
     5401 gactgacaga acgattgatt ttaaagacta tcatatccgt taccgctatc cgaaagaagg
     5461 gcctgactcc gatctgattt ggagaccgga tgaaaggatc accattccat ccggcgaaac
     5521 ttttgtggtt tggctgaagc ctgtcgggca tccagaattg acggcggagg atttcaatcg
     5581 atattaccag acacaattaa cggaagggaa aaatctcgcg gtattagaag agacagaggg
     5641 gatggccaat actaggccgc ggtcagttgt gatatcaacg aatacaggaa aagatatttc
     5701 ggtcgcgcat tatcggaaac atgcgctgcg ccggctgtca tctgtgcttt acaagtatcc
     5761 gctggacgga accgcagaac ttctcaatat ctcaatcgga gaaaaaaatc cgtccccggg
     5821 aacggtatta caggcgcaag ttcctgagca gaaacgaaaa attaagcttg ataaagaaaa
     5881 gccggtcatt gaggatttga ctgaccgcaa gcctgttcgc cctgctgaaa gcattgagct
     5941 gcgggctgat atacgggacc gcagtcttgt gaaaacagcg gccttctact atcggacaga
     6001 tgaaaacaaa ccgtttaagc gcattctcac tgaaaaagac cgcaacgaca atctctacca
     6061 ttatattgtg tattcgcctg aactgatcgg gaaggatcag cttgagtatt acgtggcagc
     6121 aggggacgga atcaacgagg cgagaacgcc ggtcaaaatg attgatatta aacaaacaag
     6181 caaatcgcac ggtttgcgga tgaacattga aaacagagac acgctatcgg gaactcagtt
     6241 tctcaaagcg acaacagacg ggcgcactaa cagcattaag ctgtggatag acggaaaaaa
     6301 acaagtgaca gagcccgcta tggaaaaaga agtgtatttt gcgttcgata cgagaaaaac
     6361 gaatctttac tttaaaaacg cggtaacgat ggaaggcaaa gtgttaaagg tatttgatga
     6421 tacaacaaat aaataccgca cctattctgt tcccttacca gagttgctgc tccgtaaagg
     6481 gaagcagctg cagcgtatta cgatacgatc aggttcaaag gtgtctccat ttgatacggc
     6541 tgaaaaccgt gatgatttct tagtcaaaaa cgcccgattg gtgttatcgg atgggacggt
     6601 gatcagggat cagagggttt ctcctgagaa ggaactcttt attggagata atcagcgctc
     6661 gaataaaagc tggcaatttc aattcaatct tcctgacgga ctgtttacgt cacagttgct
     6721 gaagtgggat acatcaaagc tttctgaagg cgctcaccat attcaagcaa gcgacggcaa
     6781 ggaaaatgta agcttggttg tgcgtgtaga taattcgggg ccgcatatcg agccgaatat
     6841 caccgaggga caaacgtaca aaggaaacct catcctgcag gcggatatgt atgataaatg
     6901 gagcaaaatt gaggaagcgg aggcgtcttt agatggtgag agcattacac ttccctacca
     6961 tacgtcatct tctgaacttt tgccgggaaa acattctcta aaaataacag caacggacct
     7021 cgcgggcaat aaaacagtaa ttgagcggac gtttaaaaca gaacgtgagc atccggatca
     7081 gccggagatc atagacagcg aagccgatac gcatagggct aagctttctg tgcgggtgaa
     7141 ggatccgacg gatgacccca tggatgtcgc tttttataga ggatttcaat atacagcacg
     7201 aaacaatgtg aaaatattca agcacgcgtc actgactgaa ccgccgaaaa gctttgtgcc
     7261 ggaaaatgag acccccttta cgaataaaga attggagcgg gtatctgctg ttgacggaaa
     7321 aacagtatcg acagaaaaga aggagctttt cccttatcat cgctttgaag tgacggttga
     7381 tccgtcagtt gatgagaatg acttggcgga agcggtctgg aagggaagtt ctttgccggg
     7441 aagaaaggtg acgatgtatg cttggaatta ccggacaaac gagtggcagc cggttgacag
     7501 cttcgttgcc aaagatcaca aaccgtttac gctgaaggcg tcagtaatcg cctccgattt
     7561 tgtgcggaag tcgaagatga atgtgattgt ccaggatgaa attcctcctg cgaaggatat
     7621 gtacacattt gcctggatgt ccgatacaca gtattacgcg gaaagctatc cgcatatttt
     7681 tgataaacag accgcatgga tcaaaagcaa tcaaaagcag ctcaatatca aatatgtgtt
     7741 tcacacgggt gatattgtag atgattctgc cgatatcaga cagtggaaaa acgctgatcg
     7801 gtcaatgtct gttctggata aaagcgggat tccttacggc gtgctggcag gtaaccacga
     7861 tgtcgggcat aaggacggct cctacagggc gtttggcaaa tactttggca gtcatcgttt
     7921 tgataaaaaa ttgcattatg gcggttctta taaaaataac cgcggacatt atgacttaat
     7981 ttcgagcaac ggcaatgatt atatcatgct gtacatggga tggggcatta cggatgaaga
     8041 catcgcgtgg atgaatcaag tgctgaagaa gcatcctgac cggatggctg ttttagcttt
     8101 tcatgagtat ttgctggtca gcggaaacag aagcccgatc ggagagaaga tattcaaaaa
     8161 agtcgtgaag ccgaatccga atgtggtgat ggtgttaagc gggcattatc atagtgcgat
     8221 gagaaaaact gatgagctgg atgatgatgg tgatggaaaa ccggatcgcc tcgtgcatca
     8281 aatgctggcc gattatcagg gcgggccaga aggcgggcaa gggtatttgc gtttgctgca
     8341 gtttgaccag gcgaatgata tggtgcatgt gtcgacgtac tctccgcatt tacaagataa
     8401 aaactactat gatacggata cctacggcaa caaggatgag ttttcgcttt cgcttgattt
     8461 gaagccgagg gtcaaaaagg tggaaaccga ttattttgaa tgtaatgtat ataccaatga
     8521 agagctcgga aaacgggagc aagtgaagag cggggatacc gctgaattcc gctgggatga
     8581 tcttgaaccg cactctgttt attattggta caccattgtg gaagacagct ttaacggcaa
     8641 aacgaaatca ccgatctgga agttcaagac gaaaaaagag acatatcgtc cgtcgccaga
     8701 ccagtttgat tttcgccatg tctccaatcc ttaaaagggg ttggagattt ttttatgaaa
     8761 gccggtccat atagtggaca aatgtataac ggtcgcctct gtatactgat tttgcatgtt
     8821 caaaagcagt tccgttctgt aaatacgttg ttcgtttgat taacaggaca ggcgcccctt
     8881 tttgaatgcc aaggatgctt gcttctttcg atgttgcagc gcttggttca agctcctgtt
     8941 ttgcacggga aatcgggatg ctgttgtact tttcaatatg ctcgtaaatc gacgactgaa
     9001 aatgcgattc gtttaattca cccgcaagct cgaacggaat atgcgaggat tcaattgcca
     9061 tcggaatatc atttgccagc cgcacccgag tgattttatg gataggagag ggatgcccgc
     9121 agcctaataa agctgcgagc tcctcagttg actcaataag ctgatagtca atgagcctgc
     9181 tgcccggtgt catcccgcgg cttttcatat cctcggtaaa gcttgtaagc ccttggagtg
     9241 cttgttccat ttttggcttg ctgacaaagg tgccccgtcc tttcaggcga taaagaaagc
     9301 cttcattgac taaattagaa agcgcctggc gaaccgtcat ccggctgatt ccgaattgtt
     9361 cggcatattc acgctcggag ggaagaggca tatccggctg cagctctccg ctcttaattt
     9421 gggcttttaa ttgctccata atctgataat acatcggaat aggcgattgt ttatcgatat
     9481 tcataagtca gcatgttcct ttcaaggtct taatgccgcg gcttcacgat caatcaaaat
     9541 cgtaacatcg gggtgcaggt gcaaagccga tgctgggaaa tcttcgctta cgtctccttc
     9601 taacagcttt ctcgcagctt ccgctttgct tttgccggaa ataagcagca gaatgcgctt
     9661 gcttgagaga atcgtctgta ttcccattgt gagtgctttt ttcggcacac tgtctattga
     9721 agaaaaatat ctggcattcg cctggcgggt ttgttcattt aatgtcacaa cgtgtgttcg
     9781 cgacttgaaa ggcgttcccg gttcgttgaa gccgatatgt ccgtttcggc cgatgccgag
     9841 aagctgaatg tcagtgccgc caatggattc gactagttgt tcgtaccgcc tgcattcggc
     9901 ttccaggtcg tctgcatttc cattgggaat aaaatgccgg tttggctggc tgtcgatatg
     9961 ctgaaaaaaa cgagaattca tatagtagtg atagctgttc ggatcatcgc ttgaaagtcc
    10021 ggcgtattca tccaaattaa ccgtggtgac gtttttaaat gaaagattct cagtttggtg
    10081 caggcggatc agctcgcggt acgtgccttc cggtgtgccg cctgttgcta aaccgagaac
    10141 ggcgtcaggt ttttccttga ttgtgtctgc tgctattctg gctgcttttt ggcttagctc
    10201 ttcatatgtt tgacattcca ctactttcat atctggtcag cctccttgga tataaatgca
    10261 atgtttccgc ggcagatggt gagaatcacc tcgcaatcac tgctgacaat cacaagatcc
    10321 gcatcttttc cctctgtcac actgcctttt cggtcaaaga tgcccagctg tttagccgcg
    10381 tttgcagaag ttatattagc tatatccgtc caagagcaat ttgtaaactc acgcatatgc
    10441 cgtgcgcctt cgttcatttt aagaatcgaa ccggcaagtg ttccgtcgga aagaagagct
    10501 gtctttcctc ttaccgtcac actttggccg ccgaactcgt atacaccatc tttcaggcct
    10561 tttgccctca tggaatcggt aattaaaatg agcttgctgc tgccttttgc caaaaaagca
    10621 agctttgccg ctaaaggatg ggagtggatg ccgtcagcga taagctctgt cacaaaccca
    10681 tcatgggcta gcgccgttcc gatcactccg ggctctcggt gatgaaacgg gctcatcgcg
    10741 ttgtaaagat gggtcatatg gctcgcgcct gctttcgcgg cctccgacag taatgcggag
    10801 tcggcatctg tgtgccccat cgacgcgata atcgattcgt cttttaaata gtggatcagt
    10861 tcaaaatgct gatcctcctc cggcgcaagt gtgacgattt tgatcagtcc gcccgcctcc
    10921 tgctgccatt ttttgaaaag cgcaacatcc gaaggcctga tacattcctt tggctgtgct
    10981 ccggctcttt taggtgaaac aaagggcccc tccaaatgaa tgccgagcag ttccgcgcct
    11041 aataaagagg attcttcagc tgctttccaa tctcttgcat tcaccaaagc ttgggaaatg
    11101 tgcccatgtt cctgggtaat ggttgttgct aaaaagctcg tcgtgccttc ttctggaagt
    11161 cttgaggaca tggtgtcgag agcggaaaag cttgcatcca tcgtatctgc gccatagccg
    11221 ccgtgaatat gaatgtcaat catcccggga agcaaaacgg aatctgccgg tgcttgaatc
    11281 tcttttgagt aagactcttt aggccgttct gttgaaactg tgctgatttt tccgccattg
    11341 attccgacat agccattttt gattacttca ttttctgtca cgatcgcgat gcctttgata
    11401 agaagacttt ttgccatagg tgatccgcct ttctggaata tgaatacatt tattttaccc
    11461 cttttcagac tagtgatcta gaccagctga ggtgttttcc cgtcttttat aaaatctgtt
    11521 ttaggttcaa gcccgaaagt gataaaatga aagtattgtg agcaagctcg gggcagcccg
    11581 gaacaggagg aacatatcgt ggcaaaggtt cgcacaaaag acgtaatgga acagttcaat
    11641 ttggaattaa tcagcggaga agaaggggtt aaccgtccga ttacaatgag tgacttatca
    11701 agaccaggca ttgaaattgc cggatatttt acatattatc cgagagagcg cgtgcagctt
    11761 ctcggaaaaa cagagctttc tttctttgaa cagctgccgg aagaggataa aaagcagcga
    11821 atggattctc tgtgcactga tgtaacacca gctattattc tttccagaga tatgcctatc
    11881 ccgcaggagc tgattgacgc ttccgagaaa aacggcgtgc ctgtcctcag atcgccgctg
    11941 aaaacgacaa ggctgtcaag ccgtttaacc aattttcttg agagccgtct ggcgcctact
    12001 acagcgattc atggcgttct tgtcgatatt tacggtgtcg gcgtgctaat tacgggaaaa
    12061 agcggcgtcg ggaaaagtga aaccgcactg gagcttgtga aaagggggca ccgcctcgtt
    12121 gccgatgatt gcgttgaaat tcggcaggag gatcaggata cccttgtcgg aaacgcgcct
    12181 gaattaattg agcatctcct tgaaatcagg gggcttggca ttatcaacgt gatgacgctg
    12241 tttggcgccg gcgcggtcag aagcaataaa cgaattacga ttgtcatgaa tcttgaactc
    12301 tgggagcagg gcaagcaata cgaccgtctc ggacttgagg aagaaaccat gaaaatcatt
    12361 gatacagaaa ttacaaaact gacgattccc gtccgtccgg gccgaaatct cgcagtcatc
    12421 atcgaggtgg cagcgatgaa cttcagattg aagcggatgg gtctgaacgc tgctgagcaa
    12481 tttacaaaca agctggcgga cgtcattgaa gacggcgaac aagacgaata ggagttggcg
    12541 ttaaatgaat gaagcgatag aaccactcaa tccgatagct tttcagctgg ggccgttagc
    12601 cgtccattgg tacggaatca ttatcggtct cggcgctttg ctagggcttt ggattgcgat
    12661 gagggaaagt gagaaacggg ggctgcagaa agacacgttt atcgatcttg tcctgtttgc
    12721 cattccgatt gcgattattt gcgcacgaat ttattacgtt gcatttgaat gggattatta
    12781 tgcggcacat ccgggagaaa tcattaagat ttggaagggc ggcattgcca ttcacggcgg
    12841 gttaatcggc gccattttaa caggttatgt attttcaaga gtgaaaaacc tttcgttctg
    12901 gaagcttgcg gatattgccg caccaagcat tttgctcggc caggcgattg gccgctg
//
