LOCUS       NZ_JALAJD010000003     25451 bp    DNA     linear   CON 23-JAN-2024
DEFINITION  Bacillus haynesii strain S4B4I contig_0000003, whole genome shotgun
            sequence.
ACCESSION   NZ_JALAJD010000003
VERSION     NZ_JALAJD010000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus haynesii
  ORGANISM  Bacillus haynesii
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 214587)
  AUTHORS   Dunlap,C.
  TITLE     Crop Bioprotection Bacillus Genome Sequencing
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 214587)
  AUTHORS   Dunlap,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-FEB-2022) CBP, USDA-ARS-NCAUR, 1815 N. University St.,
            Peoria, IL 61604, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC NGS Cell v. 21
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 186.61533326734113x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/23/2024 03:14:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,325
            CDSs (total)                      :: 4,234
            Genes (coding)                    :: 4,160
            CDSs (with protein)               :: 4,160
            Genes (RNA)                       :: 91
            rRNAs                             :: 5, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 77
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 41 of 74
            Pseudo Genes (incomplete)         :: 45 of 74
            Pseudo Genes (internal stop)      :: 10 of 74
            Pseudo Genes (multiple problems)  :: 19 of 74
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:38:58
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 25451
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JALAJD010000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..25451
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..25451
                     /SMILES="NC(C(C)CC)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25451
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[1602:5451](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1603..5451
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     gene            <1..1546
                     /locus_tag="MOB25_RS06235"
                     /old_locus_tag="MOB25_06225"
     CDS             <3..1546
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Epimerization (46-346). E-value:
                     3.6e-168. Score: 552.7. Matches aSDomain:
                     nrpspksdomains_MOB25_RS06235_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (354-504). E-value: 1.9e-52.
                     Score: 169.1. Matches aSDomain:
                     nrpspksdomains_MOB25_RS06235_TIGR01720.1"
                     /codon_start=2
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020450106.1"
                     /locus_tag="MOB25_RS06235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_06225"
                     /product="condensation domain-containing protein"
                     /protein_id="WP_268338236.1"
                     /sec_met_domain="Condensation (E-value: 4.8e-80, bitscore:
                     262.4, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="GIQMASRLQQHGWKLEMKDLFQHPTIGEISSYIEWADAKPIDQGP
                     VEGEVTLTPIQRWFFERKFTNEHHWNQSVMLHAPSRFDPEIVEQTLAALTEHHDALRLV
                     YKKNNGRLIQYNRGPGDRSFAFRVVDLRYVTDIETEIAAQANRLQASLDLENGPLVKAE
                     QYQTAEGDHLLIVIHHLVIDGVSWRILLEDFASGYSHAAQQHDIVFPDKTNSFKDWAEA
                     LEDYAQTERFLKTADYWRRLEQERICELPKDRAAAERKAENTSAVKFELNEAETRLLLT
                     KVHEPYGTDINDILLSALSLTIREWTNDSNICINMEGHGREEIIPGINISRTAGWFTAQ
                     YPVILKNEAAAGLPETIKNVKETLRRIPDKGIGYGILRYLTDRKKVGADFSIKPDISFN
                     YLGQIDREVQTDFFGPSPYDMGRQVSESSEALYALSFSGIISKEKFILSCSFNTEEYDR
                     QTIQELMDRFKAFLTALIDHCTAKEEREFTPSDFSAGDLEMEEMGDLFDVLEENLN"
     aSDomain        143..1042
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOB25_RS06235_Epimerization.1"
                     /evalue="3.60E-168"
                     /label="MOB25_RS06235_Epimerization.1"
                     /locus_tag="MOB25_RS06235"
                     /protein_end="346"
                     /protein_start="46"
                     /score="552.7"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLVIDG"
                     /tool="antismash"
                     /translation="EGEVTLTPIQRWFFERKFTNEHHWNQSVMLHAPSRFDPEIVEQTL
                     AALTEHHDALRLVYKKNNGRLIQYNRGPGDRSFAFRVVDLRYVTDIETEIAAQANRLQA
                     SLDLENGPLVKAEQYQTAEGDHLLIVIHHLVIDGVSWRILLEDFASGYSHAAQQHDIVF
                     PDKTNSFKDWAEALEDYAQTERFLKTADYWRRLEQERICELPKDRAAAERKAENTSAVK
                     FELNEAETRLLLTKVHEPYGTDINDILLSALSLTIREWTNDSNICINMEGHGREEIIPG
                     INISRTAGWFTAQYPVILK"
     aSModule        143..1516
                     /domains="nrpspksdomains_MOB25_RS06235_Epimerization.1"
                     /domains="nrpspksdomains_MOB25_RS06235_TIGR01720.1"
                     /incomplete
                     /locus_tags="MOB25_RS06235"
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       158..187
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOB25_RS06235_0001"
                     /evalue="3.10E-05"
                     /label="NRPS-E1"
                     /locus_tag="MOB25_RS06235"
                     /protein_end="61"
                     /protein_start="51"
                     /score="16.6"
                     /tool="antismash"
                     /translation="LTPIQRWFFE"
     CDS_motif       245..319
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOB25_RS06235_0002"
                     /evalue="8.60E-05"
                     /label="C2_LCL_024-062"
                     /locus_tag="MOB25_RS06235"
                     /protein_end="105"
                     /protein_start="80"
                     /score="15.0"
                     /tool="antismash"
                     /translation="RFDPEIVEQTLAALTEHHDALRLVY"
     CDS_motif       521..586
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOB25_RS06235_0003"
                     /evalue="3.10E-12"
                     /label="NRPS-E2"
                     /locus_tag="MOB25_RS06235"
                     /protein_end="194"
                     /protein_start="172"
                     /score="38.5"
                     /tool="antismash"
                     /translation="LLIVIHHLVIDGVSWRILLEDF"
     CDS_motif       989..1039
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOB25_RS06235_0004"
                     /evalue="2.60E-07"
                     /label="NRPS-E5"
                     /locus_tag="MOB25_RS06235"
                     /protein_end="345"
                     /protein_start="328"
                     /score="22.8"
                     /tool="antismash"
                     /translation="NISRTAGWFTAQYPVIL"
     aSDomain        1067..1516
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOB25_RS06235_TIGR01720.1"
                     /evalue="1.90E-52"
                     /label="MOB25_RS06235_TIGR01720.1"
                     /locus_tag="MOB25_RS06235"
                     /protein_end="504"
                     /protein_start="354"
                     /score="169.1"
                     /tool="antismash"
                     /translation="ETIKNVKETLRRIPDKGIGYGILRYLTDRKKVGADFSIKPDISFN
                     YLGQIDREVQTDFFGPSPYDMGRQVSESSEALYALSFSGIISKEKFILSCSFNTEEYDR
                     QTIQELMDRFKAFLTALIDHCTAKEEREFTPSDFSAGDLEMEEMGD"
     CDS_motif       1082..1144
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOB25_RS06235_0005"
                     /evalue="4.40E-13"
                     /label="NRPS-E6"
                     /locus_tag="MOB25_RS06235"
                     /protein_end="380"
                     /protein_start="359"
                     /score="41.1"
                     /tool="antismash"
                     /translation="VKETLRRIPDKGIGYGILRYL"
     CDS_motif       1184..1213
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOB25_RS06235_0006"
                     /evalue="3.60E-03"
                     /label="NRPS-E7"
                     /locus_tag="MOB25_RS06235"
                     /protein_end="403"
                     /protein_start="393"
                     /score="9.9"
                     /tool="antismash"
                     /translation="PDISFNYLGQ"
     aSDomain        1603..1698
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOB25_RS06240_NRPS-COM_Nterm.1"
                     /evalue="1.20E-18"
                     /label="MOB25_RS06240_NRPS-COM_Nterm.1"
                     /locus_tag="MOB25_RS06240"
                     /protein_end="32"
                     /protein_start="0"
                     /score="58.0"
                     /tool="antismash"
                     /translation="MSQFKKEHVQDIYYLSPMQEGMLFHTLLHPGQ"
     gene            1603..5451
                     /gene="licC"
                     /locus_tag="MOB25_RS06240"
                     /old_locus_tag="MOB25_06230"
     CDS             1603..5451
                     /GO_function="GO:1904091 - non-ribosomal peptide synthetase
                     activity [Evidence IEA]"
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (0-32). E-value: 1.2e-18.
                     Score: 58.0. Matches aSDomain:
                     nrpspksdomains_MOB25_RS06240_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (9-309). E-value:
                     8.2e-120. Score: 391.4. Matches aSDomain:
                     nrpspksdomains_MOB25_RS06240_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (472-870). E-value:
                     5.4e-114. Score: 372.9. Matches aSDomain:
                     nrpspksdomains_MOB25_RS06240_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (978-1047). E-value: 6.6e-24. Score:
                     75.9. Matches aSDomain: nrpspksdomains_MOB25_RS06240_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (1063-1257). E-value:
                     2.3e-27. Score: 88.9. Matches aSDomain:
                     nrpspksdomains_MOB25_RS06240_Thioesterase.1"
                     /codon_start=1
                     /gene="licC"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006638624.1"
                     /locus_tag="MOB25_RS06240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_06230"
                     /product="lichenysin non-ribosomal peptide synthetase LicC"
                     /protein_id="WP_268338237.1"
                     /sec_met_domain="Condensation (E-value: 1.3e-88, bitscore:
                     290.6, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.6e-127, bitscore:
                     419.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1e-15, bitscore:
                     51.7, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 1.7e-25, bitscore:
                     84.2, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQFKKEHVQDIYYLSPMQEGMLFHTLLHPGQGFYIEQISMQVKG
                     SFQKNVLEKSMNVIIGRYDIFRTVFVHEKMKRPLQVVLKERSFQAEEIDLSGLSEAEQN
                     ERIEDYKRKDKEKGFNLSKDIPMRTAVFKKGQDRYEWVWSYHHILLDGWCFGIVVQELF
                     EVYQALRENRPYSLGPVRPYKEYIKWLESQDKQKSLSYWEQHLAGFEGQTTFSEQRKKP
                     EQAGNQPEELLFTLPKEDTEAFTQLAKAHHTTLSTALQAVWSVLLSRYQRSRDLIFGTV
                     VSGRPADIQGVEHMVGLFINVVPKRVTFDAHTTFTELVANLQKQALEAEPHQYVPLYDI
                     QSHIAAPNLIDHIIVFENYPLQEANKQQEEKNLGFTMDEISVFEKSNYDLNLLASPGEE
                     MLLKLAYNRNIFEPSFILQLKEQLLTAIREIIRNPEQPLADICVVSTKEKERLLHEFNG
                     QVQQKQTGLTIPQWFEQYAEAFPEQPAVSAAGRTLTYRELNEKANKVAHLLRKKNVGRG
                     EPVALLFRRSPEMVIALLAVLKAGGAYLPIDPEYPEARIQYMLKDSGAVCMLTQEELAG
                     RAASLSFHQNTILIDDPELSAESGRNLEITAEPDDLAYIMYTSGTTGKPKGNLTTHANI
                     TRVVKETNYISLSEKDTLLSLSNYAFDGFTFDVYGALLNGAKLVVADQATILHIGKLTE
                     TIQKENITVMFVTTALFNLLVDAGTEWMKGIRKVLFGGERSSVSHVKKAFAAMGPDKII
                     HVYGPTETTVFATFYPVNRMEDSAASIPIGKPINETNAYILTENNRLQPIGAVGELCLS
                     GTGVSRGYLNRPELTAEKFAPHPFNSGETMYRTGDLARWLPDGNIDFIGRIDDQVKIRG
                     HRIELGEIEEELLRCQGVKEAVVTAKKSGNGDAALTAYVVPVKGAEVASEEVRRQLARK
                     LPAYMVPDAYIMLEELPLTANGKVNRRLLPEADGRPNSTERRAPRNVTEEKLAVIWSEV
                     LGRQQIGIDENFFEIGGHSLKAMAVTSRMLKDLAIDVPVNVLFEMPTIEGLAAYIDQGG
                     HTDDVKKTVFNQESTRHLFAFPPVLGYGIVYGKLAEQMPEYKIHAFDFIESDDRAVRYA
                     EAISGLQPEGPLTLIGYSAGCGLAFEVAQTLEKNGRKVEKLLMIDSYMKNGVSDLEGRS
                     IEADTAALMEANKDNEYMKIKTVADGIAKKMAAYYSYFVNLVHQGTVSCEIHLIKSEQA
                     KPLPAWLSSWKEGTESSYDEYQGAGRHDEMLADGFVKTNADLIRQILGERAAVIGGV"
     aSDomain        1630..2529
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOB25_RS06240_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="8.20E-120"
                     /label="MOB25_RS06240_Condensation_DCL.1"
                     /locus_tag="MOB25_RS06240"
                     /protein_end="309"
                     /protein_start="9"
                     /score="391.4"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHILLDG"
                     /tool="antismash"
                     /translation="QDIYYLSPMQEGMLFHTLLHPGQGFYIEQISMQVKGSFQKNVLEK
                     SMNVIIGRYDIFRTVFVHEKMKRPLQVVLKERSFQAEEIDLSGLSEAEQNERIEDYKRK
                     DKEKGFNLSKDIPMRTAVFKKGQDRYEWVWSYHHILLDGWCFGIVVQELFEVYQALREN
                     RPYSLGPVRPYKEYIKWLESQDKQKSLSYWEQHLAGFEGQTTFSEQRKKPEQAGNQPEE
                     LLFTLPKEDTEAFTQLAKAHHTTLSTALQAVWSVLLSRYQRSRDLIFGTVVSGRPADIQ
                     GVEHMVGLFINVVPKRVTF"
     aSModule        1630..5373
                     /complete
                     /domains="nrpspksdomains_MOB25_RS06240_Condensation_DCL.1"
                     /domains="nrpspksdomains_MOB25_RS06240_AMP-binding.1"
                     /domains="nrpspksdomains_MOB25_RS06240_PCP.1"
                     /domains="nrpspksdomains_MOB25_RS06240_Thioesterase.1"
                     /final_module
                     /locus_tags="MOB25_RS06240"
                     /monomer_pairings="Ile -> Ile"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       1639..1680
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOB25_RS06240_0001"
                     /evalue="3.00E-05"
                     /label="C1_DCL_004-017"
                     /locus_tag="MOB25_RS06240"
                     /protein_end="26"
                     /protein_start="12"
                     /score="15.8"
                     /tool="antismash"
                     /translation="YYLSPMQEGMLFHT"
     CDS_motif       1699..1818
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOB25_RS06240_0002"
                     /evalue="7.20E-11"
                     /label="C2_DCL_024-062"
                     /locus_tag="MOB25_RS06240"
                     /protein_end="72"
                     /protein_start="32"
                     /score="34.4"
                     /tool="antismash"
                     /translation="GFYIEQISMQVKGSFQKNVLEKSMNVIIGRYDIFRTVFVH"
     CDS_motif       2035..2100
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOB25_RS06240_0003"
                     /evalue="3.40E-12"
                     /label="C3_DCL_135-156"
                     /locus_tag="MOB25_RS06240"
                     /protein_end="166"
                     /protein_start="144"
                     /score="38.7"
                     /tool="antismash"
                     /translation="YHHILLDGWCFGIVVQELFEVY"
     CDS_motif       2146..2184
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOB25_RS06240_0004"
                     /evalue="2.00E-03"
                     /label="C4_DCL_171-183"
                     /locus_tag="MOB25_RS06240"
                     /protein_end="194"
                     /protein_start="181"
                     /score="10.8"
                     /tool="antismash"
                     /translation="PYKEYIKWLESQD"
     CDS_motif       2425..2520
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOB25_RS06240_0005"
                     /evalue="2.00E-18"
                     /label="C5_DCL_263-294"
                     /locus_tag="MOB25_RS06240"
                     /protein_end="306"
                     /protein_start="274"
                     /score="58.8"
                     /tool="antismash"
                     /translation="DLIFGTVVSGRPADIQGVEHMVGLFINVVPKR"
     CDS_motif       2569..2682
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOB25_RS06240_0006"
                     /evalue="2.70E-18"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="MOB25_RS06240"
                     /protein_end="360"
                     /protein_start="322"
                     /score="58.4"
                     /tool="antismash"
                     /translation="QKQALEAEPHQYVPLYDIQSHIAAPNLIDHIIVFENYP"
     aSDomain        3019..4212
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOB25_RS06240_AMP-binding.1"
                     /evalue="5.40E-114"
                     /label="MOB25_RS06240_AMP-binding.1"
                     /locus_tag="MOB25_RS06240"
                     /protein_end="870"
                     /protein_start="472"
                     /score="372.9"
                     /specificity="substrate consensus: Ile"
                     /tool="antismash"
                     /translation="FEQYAEAFPEQPAVSAAGRTLTYRELNEKANKVAHLLRKKNVGRG
                     EPVALLFRRSPEMVIALLAVLKAGGAYLPIDPEYPEARIQYMLKDSGAVCMLTQEELAG
                     RAASLSFHQNTILIDDPELSAESGRNLEITAEPDDLAYIMYTSGTTGKPKGNLTTHANI
                     TRVVKETNYISLSEKDTLLSLSNYAFDGFTFDVYGALLNGAKLVVADQATILHIGKLTE
                     TIQKENITVMFVTTALFNLLVDAGTEWMKGIRKVLFGGERSSVSHVKKAFAAMGPDKII
                     HVYGPTETTVFATFYPVNRMEDSAASIPIGKPINETNAYILTENNRLQPIGAVGELCLS
                     GTGVSRGYLNRPELTAEKFAPHPFNSGETMYRTGDLARWLPDGNIDFIGRIDDQVKIR"
     CDS_motif       3205..3246
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOB25_RS06240_0007"
                     /evalue="1.10E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="MOB25_RS06240"
                     /protein_end="548"
                     /protein_start="534"
                     /score="18.6"
                     /tool="antismash"
                     /translation="LAVLKAGGAYLPID"
     CDS_motif       3439..3498
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOB25_RS06240_0008"
                     /evalue="5.50E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="MOB25_RS06240"
                     /protein_end="632"
                     /protein_start="612"
                     /score="25.1"
                     /tool="antismash"
                     /translation="AYIMYTSGTTGKPKGNLTTH"
     CDS_motif       4006..4095
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOB25_RS06240_0009"
                     /evalue="1.40E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="MOB25_RS06240"
                     /protein_end="831"
                     /protein_start="801"
                     /score="55.7"
                     /tool="antismash"
                     /translation="PIGAVGELCLSGTGVSRGYLNRPELTAEKF"
     CDS_motif       4177..4242
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOB25_RS06240_0010"
                     /evalue="9.70E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="MOB25_RS06240"
                     /protein_end="880"
                     /protein_start="858"
                     /score="39.9"
                     /tool="antismash"
                     /translation="FIGRIDDQVKIRGHRIELGEIE"
     aSDomain        4537..4743
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOB25_RS06240_PCP.1"
                     /evalue="6.60E-24"
                     /label="MOB25_RS06240_PCP.1"
                     /locus_tag="MOB25_RS06240"
                     /protein_end="1047"
                     /protein_start="978"
                     /score="75.9"
                     /tool="antismash"
                     /translation="EEKLAVIWSEVLGRQQIGIDENFFEIGGHSLKAMAVTSRMLKDLA
                     IDVPVNVLFEMPTIEGLAAYIDQG"
     aSDomain        4792..5373
                     /ASF="active site serine present: True"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOB25_RS06240_Thioesterase.1"
                     /evalue="2.30E-27"
                     /label="MOB25_RS06240_Thioesterase.1"
                     /locus_tag="MOB25_RS06240"
                     /protein_end="1257"
                     /protein_start="1063"
                     /score="88.9"
                     /tool="antismash"
                     /translation="RHLFAFPPVLGYGIVYGKLAEQMPEYKIHAFDFIESDDRAVRYAE
                     AISGLQPEGPLTLIGYSAGCGLAFEVAQTLEKNGRKVEKLLMIDSYMKNGVSDLEGRSI
                     EADTAALMEANKDNEYMKIKTVADGIAKKMAAYYSYFVNLVHQGTVSCEIHLIKSEQAK
                     PLPAWLSSWKEGTESSYDEYQGAGRHDEMLA"
     CDS_motif       4942..5016
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOB25_RS06240_0011"
                     /evalue="3.10E-10"
                     /label="NRPS-te1"
                     /locus_tag="MOB25_RS06240"
                     /protein_end="1138"
                     /protein_start="1113"
                     /score="32.4"
                     /tool="antismash"
                     /translation="QPEGPLTLIGYSAGCGLAFEVAQTL"
     gene            5455..6195
                     /gene="licTE"
                     /locus_tag="MOB25_RS06245"
                     /old_locus_tag="MOB25_06235"
     CDS             5455..6195
                     /NRPS_PKS="Domain: Thioesterase (15-231). E-value: 4.5e-49.
                     Score: 159.9. Matches aSDomain:
                     nrpspksdomains_MOB25_RS06245_Thioesterase.1"
                     /codon_start=1
                     /gene="licTE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_043926232.1"
                     /locus_tag="MOB25_RS06245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_06235"
                     /product="lichenysin biosynthesis thioesterase LicTE"
                     /protein_id="WP_268338239.1"
                     /sec_met_domain="Thioesterase (E-value: 6.4e-59, bitscore:
                     193.5, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 1.9e-07, bitscore: 24.6,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 5.9e-12, bitscore:
                     40.3, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDEIIKQFGAPASGMQLICFPFAGGYSASFRPLYEHLKADFDMLA
                     IEPPGHGTNRMALVDNLEKLVDLYIAALKPRLSSQFVLFGHSMGGMVVYRLAQKLEQEG
                     IFPAAAVISAIQPPHIQRQKVSHKNDDAFLDHLIQLGGIPQELAEHREIMSFFLPSFRA
                     DYRALETFCHIDHTPLRSPVHILNGDRDEKCMKDALGWKKWARTIDFHYFKGGHMYLLS
                     ETEQVAAKMKTIVAASRSTAVPTM"
     aSDomain        5500..6147
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOB25_RS06245_Thioesterase.1"
                     /evalue="4.50E-49"
                     /label="MOB25_RS06245_Thioesterase.1"
                     /locus_tag="MOB25_RS06245"
                     /protein_end="231"
                     /protein_start="15"
                     /score="159.9"
                     /tool="antismash"
                     /translation="QLICFPFAGGYSASFRPLYEHLKADFDMLAIEPPGHGTNRMALVD
                     NLEKLVDLYIAALKPRLSSQFVLFGHSMGGMVVYRLAQKLEQEGIFPAAAVISAIQPPH
                     IQRQKVSHKNDDAFLDHLIQLGGIPQELAEHREIMSFFLPSFRADYRALETFCHIDHTP
                     LRSPVHILNGDRDEKCMKDALGWKKWARTIDFHYFKGGHMYLLSETEQVAAKM"
     CDS_motif       5695..5754
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOB25_RS06245_0001"
                     /evalue="5.70E-06"
                     /label="NRPS-te1"
                     /locus_tag="MOB25_RS06245"
                     /protein_end="100"
                     /protein_start="80"
                     /score="18.9"
                     /tool="antismash"
                     /translation="FVLFGHSMGGMVVYRLAQKL"
     gene            complement(6242..7153)
                     /locus_tag="MOB25_RS06250"
                     /old_locus_tag="MOB25_06240"
     CDS             complement(6242..7153)
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003178840.1"
                     /locus_tag="MOB25_RS06250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_06240"
                     /product="DMT family transporter"
                     /protein_id="WP_268297728.1"
                     /transl_table=11
                     /translation="MNKTAYAAALLYAFIIGLSFFFVKLALTAASPVDILAHRFTVAFL
                     AALFPLLLGWVKIAISIKDALKVLPLALFYPVMFFAFQVFGLVYTSSSEAGIIQAAIPI
                     FTMIFAAYFLNERFTKRQFFFTVLSAAGVACIFMMKSAGNGSSDLRGAALILLSALSSA
                     GYSVLARKMTRTFSSLELTYVTTGAGFLFFNGIAGISHMSDGTLSGFFAPFTDPVFVLS
                     VLYLGVMSSFATSFLSNYALSKIEAAKISMFNHLATLVTILAGIIWLGESLEWFHFAGT
                     GMIIAGMIGATMVRRENWLKKS"
     gene            7288..8637
                     /locus_tag="MOB25_RS06255"
                     /old_locus_tag="MOB25_06245"
     CDS             7288..8637
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (96-440). E-value:
                     4.9e-26. Score: 83.6. Matches aSDomain:
                     nrpspksdomains_MOB25_RS06255_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003178841.1"
                     /locus_tag="MOB25_RS06255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_06245"
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_268338241.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.6e-25, bitscore:
                     83.7, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHKYVALMNQLEDMIEDKSFQEGDRLPSIRALSVRFNVSKSTVIR
                     AFNELERRHLIYSVPKSGYYVVKKTNQRSNPGKAVIDFAASAPDPDVFPYIDFQHCINK
                     AIDTYKNDLFIYGTPKGLPSLIEAIQKELANGQVFAKEEHIFITSGVQQALALLASMPF
                     PNGKRKILIEQPSYHLLIQYLEVHGIPAIGIERTAEGIDMDELERIFQTEDIKFFYTMP
                     RFHNPLGTSYTEKEKMAIVKLAEKYDVYIAEDDFLGDLENHKKADPLHYYDVSSHVIYL
                     KSFSKIIFPGLRVGAAVLPDSLTDVFNRYKQLLDIDSSMLSQAALEIYLKSGMFEKHKQ
                     KIRSSYQKRSCLLHDLLKECAASLGDVFEFHPPAHPAIHTHIELDRTIPVSRLIKSIKK
                     RDVLLEPVNAHYMSTFPKRNLLKINTSNVKEVDIRRGIERLRQAVETTYF"
     aSDomain        7576..8607
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOB25_RS06255_Aminotran_1_2.1"
                     /evalue="4.90E-26"
                     /label="MOB25_RS06255_Aminotran_1_2.1"
                     /locus_tag="MOB25_RS06255"
                     /protein_end="440"
                     /protein_start="96"
                     /score="83.6"
                     /tool="antismash"
                     /translation="DFQHCINKAIDTYKNDLFIYGTPKGLPSLIEAIQKELANGQVFAK
                     EEHIFITSGVQQALALLASMPFPNGKRKILIEQPSYHLLIQYLEVHGIPAIGIERTAEG
                     IDMDELERIFQTEDIKFFYTMPRFHNPLGTSYTEKEKMAIVKLAEKYDVYIAEDDFLGD
                     LENHKKADPLHYYDVSSHVIYLKSFSKIIFPGLRVGAAVLPDSLTDVFNRYKQLLDIDS
                     SMLSQAALEIYLKSGMFEKHKQKIRSSYQKRSCLLHDLLKECAASLGDVFEFHPPAHPA
                     IHTHIELDRTIPVSRLIKSIKKRDVLLEPVNAHYMSTFPKRNLLKINTSNVKEVDIRRG
                     IERL"
     gene            complement(8649..9329)
                     /locus_tag="MOB25_RS06260"
                     /old_locus_tag="MOB25_06250"
     CDS             complement(8649..9329)
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /NRPS_PKS="Domain: ACPS (103-166). E-value: 1.9e-19. Score:
                     61.8. Matches aSDomain:
                     nrpspksdomains_MOB25_RS06260_ACPS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1012: 4'-phosphopantetheinyl transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003178843.1"
                     /locus_tag="MOB25_RS06260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_06250"
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="WP_268338242.1"
                     /transl_table=11
                     /translation="MKIYAVYMDQLPEAGQFNRMMAMVSEEKRKKVGRYRYPEDASRTL
                     IGEVLARHIISETFHLPNDQIRFTEGRYGKPAAEGLNDFHFNISHSGKWIVCGAGTQPI
                     GVDVEMIKPINFDIAKRFFSPSEHHDLMEKDESERLSYFYHLWTMKESFIKQAGKGLSL
                     PLDSFSVKLNEQGRASVETPPGYPPCYIQAYEIDPGYKMAVCSAAPEFPDRIVMKSCAE
                     LSML"
     aSDomain        complement(8832..9020)
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOB25_RS06260_ACPS.1"
                     /evalue="1.90E-19"
                     /label="MOB25_RS06260_ACPS.1"
                     /locus_tag="MOB25_RS06260"
                     /protein_end="166"
                     /protein_start="103"
                     /score="61.8"
                     /tool="antismash"
                     /translation="IGVDVEMIKPINFDIAKRFFSPSEHHDLMEKDESERLSYFYHLWT
                     MKESFIKQAGKGLSLPLD"
     gene            9429..10214
                     /locus_tag="MOB25_RS06265"
                     /old_locus_tag="MOB25_06255"
     CDS             9429..10214
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1098: enterobactin/ferric enterobactin esterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009330220.1"
                     /locus_tag="MOB25_RS06265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_06255"
                     /product="alpha/beta hydrolase-fold protein"
                     /protein_id="WP_268338244.1"
                     /transl_table=11
                     /translation="MIDGTLIKDTYSGRELLIYLPPSYGSGENRYPVLYVQDLGDLFDP
                     AYSGSLRSIEKLFLNQEVPELLLVGVAPKDRESEYTPFPKPHLLPNKREYGGKGNEYAA
                     FLANRLKPYIDRYYRTNPSREHTGIIGKSFGGLISVYTAYLASDTFGKIGSLSGSFWFE
                     GMTEFMKNNRFENEHMRIYMDVGSTEGADRDNLQKEMIPRTKEAFSLLTESAASEKELK
                     FVIDEGGSHRLERFAKRFPEAVKWLFGSCHNSARNDRNF"
     gene            10255..10512
                     /locus_tag="MOB25_RS21625"
     CDS             10255..10512
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MOB25_RS21625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_326323094.1"
                     /transl_table=11
                     /translation="MDILNRLAESIDYIEKYLDQPLKHEEIAKIAYCSKFHYQRMFYML
                     TGVTLADYIRKRRLTVAAQELAAKWLMLLLNTATTHRNHF"
     gene            10667..11092
                     /locus_tag="MOB25_RS21630"
     CDS             10667..11092
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018184.4"
                     /locus_tag="MOB25_RS21630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GyrI-like domain-containing protein"
                     /protein_id="WP_326849991.1"
                     /transl_table=11
                     /translation="MKDDQNKKDIPAFWNELNHNGFTDSLKPHIGPLGFLGVCMDFNDQ
                     ADTFNYVIGVEKTTADTPAGCVEKPIPAATWAVFEAIGPVNPAVQATWERIFSEWFPAT
                     GYELANAPQFESCPKDGDIMAQDHITEIWIPVVKKKI"
     gene            complement(11115..11777)
                     /locus_tag="MOB25_RS06275"
                     /old_locus_tag="MOB25_06265"
     CDS             complement(11115..11777)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003178846.1"
                     /locus_tag="MOB25_RS06275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_06265"
                     /product="YitT family protein"
                     /protein_id="WP_075753853.1"
                     /transl_table=11
                     /translation="MKRELVLRWLFYFVGLIVLSFGVSLTIEGKVLGIGPWDAFHYGLY
                     MLLGLTVGQWAIIVGAVIVGLTSLFTKAWPKIGAVLNMLLIGIFIDFFTYILPDPETYI
                     SSTVVFVIGVIFIGYGVGIYVSADLGAGPRDSLMLLISEKTGWNVQWVRNGMELTILLI
                     GWLLGGPIGIGTVLTAILTGLILRFSLPQSKQLLKAAMTGRRIRAAKPVHMSLKKNG"
     misc_feature    11788..11801
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.31"
                     /tool="antismash"
     misc_feature    11809..11825
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 22.29"
                     /tool="antismash"
     misc_feature    complement(11876..11889)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 20.58"
                     /tool="antismash"
     gene            11940..12158
                     /locus_tag="MOB25_RS06280"
                     /old_locus_tag="MOB25_06270"
     CDS             11940..12158
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MOB25_RS06280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MOB25_06270"
                     /product="hypothetical protein"
                     /protein_id="WP_268306949.1"
                     /transl_table=11
                     /translation="MEGRNSETWQSIVIRDHFIYVDGSIIGQSYLAEPMGEPGAWDVLV
                     CWLFVHCGSAVCSGKTADFMKKGGEWR"
     gene            12149..12337
                     /locus_tag="MOB25_RS06285"
                     /old_locus_tag="MOB25_06275"
     CDS             12149..12337
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009330211.1"
                     /locus_tag="MOB25_RS06285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_06275"
                     /product="hypothetical protein"
                     /protein_id="WP_225315912.1"
                     /transl_table=11
                     /translation="MALIFLVRLICLAFLACLALLFILNYAPFLAMPVWIALIIALIVC
                     LYLAFIEEMKEWRRRKH"
     gene            complement(12346..12594)
                     /locus_tag="MOB25_RS06290"
                     /old_locus_tag="MOB25_06280"
     CDS             complement(12346..12594)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MOB25_RS06290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MOB25_06280"
                     /product="hypothetical protein"
                     /protein_id="WP_268308535.1"
                     /transl_table=11
                     /translation="MNHEKEKKTFSMRMVFNVVGLFAFIGMTVGAYTQAYYLDEHLELR
                     RFAYMTALEWKEFLLFVSGTAVIYFVLANVLLYKKKR"
     misc_feature    12564..12578
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.26"
                     /tool="antismash"
     misc_feature    12667..12684
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 18.15"
                     /tool="antismash"
     misc_feature    complement(12787..12798)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.67"
                     /tool="antismash"
     gene            12832..14493
                     /locus_tag="MOB25_RS06295"
                     /old_locus_tag="MOB25_06285"
     CDS             12832..14493
                     /GO_function="GO:0016830 - carbon-carbon lyase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0019752 - carboxylic acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180: Decarboxylase, pyridoxal-dependent"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003178859.1"
                     /locus_tag="MOB25_RS06295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_06285"
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="WP_268338246.1"
                     /transl_table=11
                     /translation="MQQRNTPDVQRWFPSEDGNEAKRNEFLSLIEQLIEGVDKLKNPDQ
                     VNLDGEKNREGFFYEKLVADSRIPYEGAPMKEVNEELLKLLHGHPYHTKYFFTNILPMA
                     SIPGILGMLTAFMVNGNNLWDVYGPAGAEAEVKVTAMMSKLAGYDAETSGGYTTWGGQG
                     AVYSGLRIAIAKMAPSALKEGVPGNFYAFCSEAAHYSLYKSMEAAGLGSDHLIKVKTNL
                     DHSMDTEDLRAKLRKVCEAGGIPVYIVATTGTTDAIGIDDVSAVRRAAEETAKSFGLPV
                     PHIHADSALGGFFAFFNEYDLNENALSFSPGVLSMIKPIQEKMRHLHAADSLCFDFQKL
                     GQTPYVTSLFLVKDRNDLKRIDLDPDETPYVGHRGYGDYHTGYTLECSRMASSISMYSA
                     LMAFGYEGYQKLLAQFLEVNLHFREQLSQQIPEADIVNPDNCGMSTLFRIYPEGAPRFE
                     DEISGACTIQELERNNALTEKLFEKLGTKRDKMFFGDTKKHLLVKSCEGTETPLCVSKF
                     FVISPYTMPEHVPGIIDYLKENIKEVCREYGSLMTN"
     gene            14508..16232
                     /locus_tag="MOB25_RS06300"
                     /old_locus_tag="MOB25_06290"
     CDS             14508..16232
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1061: methyl-accepting
                     chemotaxis protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003178861.1"
                     /locus_tag="MOB25_RS06300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_06290"
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="WP_268301452.1"
                     /transl_table=11
                     /translation="MKTLKKKLTEHISVKIMIGVALVLLITIASFSAVFTFISKDLSEQ
                     LKQQFQNRLYTDIHLAENQIKRLDGNPLEIDSADNPLYKQTKMAVDSLKKKNKLENIYI
                     LSNEGGKERILVLSDTSDDFGTDYSFSPEMKEALTTNKETVSDVYEDEYGIHQSIFLPL
                     ENGSGEKVGILGIDLDASVIPATAAKAKWYTIAISAFVLLLGMVMAYLLGSYIAKPIRQ
                     LMKASEKIADGDLSADISVKSRDEAGKLAESFKRMSENLQQLIGHISASSEEVSKTSLQ
                     LKNVSAESSESAVQVAESMNSMSEGINEVVSSVSDCHTSAAEIDHQLSHVTEEVNEMKN
                     VAEGVSKDSKTGQELVGETLRQTQTIKNVMEESKQAAAEMQNHTEEIEKVIGMISSIAE
                     QTNLLALNASIEAARVGEEGQGFAVVAGEVRKLSERSADAALSVSQLVAGTQESSRLVM
                     ERIQEGNEAVDKGQILINGTYENFSGIFKGISQFAERTDQLLQSLLKVEKSYQNISSAM
                     EQISSVTEEQAAGSEEVAAAAEQQSAGMQEIASAIQQLSALSEELNQAASKFKLAAE"
     gene            complement(16271..17014)
                     /locus_tag="MOB25_RS06305"
                     /old_locus_tag="MOB25_06295"
     CDS             complement(16271..17014)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388241.2"
                     /locus_tag="MOB25_RS06305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_06295"
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_268301451.1"
                     /transl_table=11
                     /translation="MLAIKGLNKSFGENEILKKIDLNIEKGKVIAILGPSGSGKTTLLR
                     CLNALETPNRGILSFDDFTIDFSKKNKPADLLRLRRKSGMVFQAYHLFPHRTVLENVME
                     GPVKVQKRNKQEVKKEAVQLLQKVGLEDKMDLYPFQLSGGQQQRVGIARALAIKPELML
                     FDEPTSALDPELVGEVLKVMKDLANEGWTMVVVTHEIKFAQDVADEVVFIDGGVIVEQG
                     PPEQIFSAPKEERTKQFLNRILNPV"
     gene            complement(17030..17734)
                     /locus_tag="MOB25_RS06310"
                     /old_locus_tag="MOB25_06300"
     CDS             complement(17030..17734)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388242.1"
                     /locus_tag="MOB25_RS06310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_06300"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_043926244.1"
                     /transl_table=11
                     /translation="MFLSNIQAAAIGAAIPWDLVRESFWPIFLRGIYYSIPLAILSFIF
                     GMIIALITALARMSKSRILRAVFGIYVSAIRGTPLLVQLFIIFYLFPAFQITIDPFPSA
                     IIAFSLNVGAYASEIIRASILSVPKGQWEAAYSIGMTQKTALTRVILPQAVRVSIPPLS
                     NTFISLVKDTSLASQILVAELFRKAQEIGASNLDQILIIYMEAAFIYWIICFVLALVQQ
                     QIERRLDRYVAK"
     gene            complement(17721..18527)
                     /gene="tcyA"
                     /locus_tag="MOB25_RS06315"
                     /old_locus_tag="MOB25_06305"
     CDS             complement(17721..18527)
                     /codon_start=1
                     /gene="tcyA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388243.2"
                     /locus_tag="MOB25_RS06315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_06305"
                     /product="cystine ABC transporter substrate-binding
                     lipoprotein TcyA"
                     /protein_id="WP_242793746.1"
                     /transl_table=11
                     /translation="MKKAIFAVLLTLLITVMAACGASGDNSKDKNAAGDSLWSSIKDKG
                     VLTVGTEGTYEPFTFHDKKTDKLTGYDVEVMQEVAKRLNLKVEFKETQWDSMFAGLNSK
                     RFDVVANQVGKKDREDQYDFSDSYTTSQAVVVTKADNNDVKSEGDVKGKKAAQSLTSNY
                     NDLAKNAGAEIEGVEGMAQAFQLIQQGRVDLTFNDKLAVLNYLKTSGNKNLKVAFETGE
                     PQTTHFAFRKGSGELVDKVNSALKDMKEDGTLAKIAKKWFGEDVSK"
     gene            complement(18656..20068)
                     /locus_tag="MOB25_RS06320"
                     /old_locus_tag="MOB25_06310"
     CDS             complement(18656..20068)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008134 - transcription factor binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1112: sigma-54
                     dependent trancsriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017473992.1"
                     /locus_tag="MOB25_RS06320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_06310"
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="WP_268301450.1"
                     /transl_table=11
                     /translation="MLKDYDLLKFIFQRIIDEIDIGLHVVDENGTSVVYNKKMSQIEGM
                     DVGDVLGKNVLDVFTFASQHDSTLLQALHHGKTNKNVKQTYFNNKGQEITTVNHTFPIM
                     ENGNTKGAVEIAKDVTKLERLIRENMNKTENTKYTFDSLIGVSPAFKEVIEHAKRATRT
                     SSSILIVGDTGTGKELFAQSIHNGSQRSTGPFISQNCAALPGSLVEGLLFGTVKGAFTG
                     AVDRPGLFEQADGGTLLLDEINSLDFSLQAKLLRAIQEKTIRRIGAAKDTPIDVRIIAT
                     MNEDPVDAVSGQRLRKDLYYRLSVVTLFIPPLKERKEDIMPLTQHFIDKYNALFQMEVK
                     GFEEDVRRFLLSYDWPGNVRELEHLIEGAMNLMSYEDKMELTHLPLQYRTKPAAKEQLP
                     QQGYDLFAPLPSASAAPLKEQIENAEKYYIQKTVKKCNYNVSQAARVLGISRQSLQYRL
                     KKWKIRFDQEPE"
     misc_feature    complement(20024..20038)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.22"
                     /tool="antismash"
     misc_feature    complement(20196..20210)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     strong, score: 24.36"
                     /tool="antismash"
     misc_feature    20227..20240
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.31"
                     /tool="antismash"
     gene            20310..21512
                     /locus_tag="MOB25_RS06325"
                     /old_locus_tag="MOB25_06315"
     CDS             20310..21512
                     /GO_function="GO:0004587 - ornithine aminotransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (28-349). E-value: 1.1e-118.
                     Score: 388.1. Matches aSDomain:
                     nrpspksdomains_MOB25_RS06325_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003178876.1"
                     /locus_tag="MOB25_RS06325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_06315"
                     /product="ornithine--oxo-acid transaminase"
                     /protein_id="WP_268297739.1"
                     /sec_met_domain="Aminotran_3 (E-value: 5.5e-139, bitscore:
                     456.9, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVLSKSEKIMKQTAHFGANNYHPLPIVISEAEGAWVKDPEGNRY
                     MDMLSAYSAVNQGHRHPKIIQALKDQADKITLTSRAFHNDQLGPFYEKVASLTGKDMVL
                     PMNTGAEAVESAIKAARRWAYDVKGVPDNQAEIIACEGNFHGRTMLAVSLSSEEEYKRG
                     FGPMLPGIKLIPYGDLEALKQAITPNTAAFLIEPIQGEAGIVIPPEGFLKQAAEACKER
                     NVLFIADEIQSGLARTGKMFASDWEDVKPDMYILGKALGGGVFPISCIAANRDVLGVFN
                     PGSHGSTFGGNPLACAVSIAALEVLEDERLAERSLELGEYFKEKLSQIDNPKIKEVRGR
                     GLFIGVELTEAARPYCERLKEEGLLCKETHETVIRFAPPLVISNEDLDWAIEKITRVLS
                     K"
     aSDomain        20394..21356
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOB25_RS06325_Aminotran_3.1"
                     /evalue="1.10E-118"
                     /label="MOB25_RS06325_Aminotran_3.1"
                     /locus_tag="MOB25_RS06325"
                     /protein_end="349"
                     /protein_start="28"
                     /score="388.1"
                     /tool="antismash"
                     /translation="ISEAEGAWVKDPEGNRYMDMLSAYSAVNQGHRHPKIIQALKDQAD
                     KITLTSRAFHNDQLGPFYEKVASLTGKDMVLPMNTGAEAVESAIKAARRWAYDVKGVPD
                     NQAEIIACEGNFHGRTMLAVSLSSEEEYKRGFGPMLPGIKLIPYGDLEALKQAITPNTA
                     AFLIEPIQGEAGIVIPPEGFLKQAAEACKERNVLFIADEIQSGLARTGKMFASDWEDVK
                     PDMYILGKALGGGVFPISCIAANRDVLGVFNPGSHGSTFGGNPLACAVSIAALEVLEDE
                     RLAERSLELGEYFKEKLSQIDNPKIKEVRGRGLFIGVELT"
     misc_feature    21598..21612
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.7"
                     /tool="antismash"
     gene            21726..23129
                     /locus_tag="MOB25_RS06330"
                     /old_locus_tag="MOB25_06320"
     CDS             21726..23129
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0003333 - amino acid transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009330205.1"
                     /locus_tag="MOB25_RS06330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_06320"
                     /product="amino acid permease"
                     /protein_id="WP_268297874.1"
                     /transl_table=11
                     /translation="MKSRHLFMISLGGVIGTGFFLGTGYTINEAGPIGAILSYLAGGMI
                     MYFTMLCLGELAVAMPVSGSFQTYATKFIGPATGFAVGWIYWLGWSVTVALEFLSAGQL
                     MKRWFPDVGVWIWCLIFGLLLFSLNALSAKAFGESEFWLSGIKIIVILLFIILGGGAMF
                     GLIDMKDGQAAPFFSNLIGDGIFPNGFGAIFITMITVNFAFQGTELIGIAAGESENPEK
                     TVPRSIKQTVWRTLVFFGLSVFVLAGLIPWEKAGVVESPFVVVFEQIGIPYAADLMNFV
                     ILIALLSVANSGLYASTRMLYSLAKEGMAAQALSRVNKRGIPMNALWITLGFAGLSLVS
                     SVVAAETLYIWLLSLAGLSAQVGWITITVSQLLFRRRYVKEGGKVEDLKFKTPLYPYLP
                     LAGFILNSAVLVSLAFDSEQRMALYCGILFMSACYFVYHVFVKKRQALERQETMIYQNK
                     TNDEVVIDE"
     gene            23122..24015
                     /gene="rocF"
                     /locus_tag="MOB25_RS06335"
                     /old_locus_tag="MOB25_06325"
     CDS             23122..24015
                     /EC_number="3.5.3.1"
                     /GO_function="GO:0004053 - arginase activity [Evidence
                     IEA]"
                     /GO_process="GO:0019547 - arginine catabolic process to
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /gene="rocF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391912.1"
                     /locus_tag="MOB25_RS06335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_06325"
                     /product="arginase"
                     /protein_id="WP_043925967.1"
                     /transl_table=11
                     /translation="MNKQVSLIGMPMDLGQARRGVDMGPSAIRYAHIVERLNELGYDID
                     DLGDVPINRDQPKGDEGLKNLVSVLEGNRKLADIVDNVVEQRRFPLVLGGDHSIAIGTL
                     AGVAKHYQQLGVIWYDAHGDLNTLETSPSGNIHGMPLAVSLGVGHEKLVNLHGYAPKIK
                     PEHVVIIGARSLDEGERKYIRETGMKVYTMHEIDRLGMTKVIEETIEYLSANCDGIHLS
                     LDLDGLDPSDAPGVGTPVVGGISYRESHLAMEMLYDADIITSAEFVEVNPILDHKNKTG
                     EAAVELIESLLGKKLL"
     gene            complement(24083..24955)
                     /locus_tag="MOB25_RS06340"
                     /old_locus_tag="MOB25_06330"
     CDS             complement(24083..24955)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014662756.1"
                     /locus_tag="MOB25_RS06340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_06330"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_268304608.1"
                     /transl_table=11
                     /translation="MDIRQLKYFVTIAQEGKITTAAKRLHIAQPPLSRQLKQMEEELGV
                     VLFDRNKKKNLTLTYEGEVFLKRAKEILHKLEDSILEVRELREEVNGTLAVGSTIYCAA
                     LLLAKVSKIRDMYPNLMFNIWEGEPSRLSELLESRQIDAAVTTTPFHSKNIESKSLPEV
                     PCKLVLPGNQSYGLKGEAGMKEIAGLPLILLRPSHGKGIYDEVVHHFQSSDLEPRVVCE
                     CHDSTTLLSLVTSGFGATILPLSMLPAHFARHVQTLEIQDNPFILQPSVVWRAGSFLPK
                     PVREFLALF"
ORIGIN
        1 aggaattcaa atggcaagcc ggcttcagca gcacgggtgg aagctggaga tgaaagactt
       61 gtttcagcac ccgacgatcg gagagatcag ttcgtatatt gaatgggcag acgctaaacc
      121 gatcgatcaa ggcccagtcg aaggcgaagt cacactgacg ccgatccagc gctggttctt
      181 tgagcgcaaa tttacgaacg agcatcactg gaatcagtcg gttatgcttc acgccccttc
      241 aaggtttgac ccggagatcg tcgaacagac attggcggca ttgacagagc atcatgatgc
      301 cctgcgcttg gtgtataaaa aaaataacgg ccgcctcatt caatataacc gcgggccggg
      361 ggaccgttca ttcgcctttc gagtggttga cctacgctat gtcacagaca ttgaaacgga
      421 aatcgccgcc caggcaaacc gtctccaggc aagccttgat ctcgaaaacg ggccgcttgt
      481 aaaggctgaa cagtatcaga ctgcggaagg cgaccatttg ctgatcgtca ttcaccattt
      541 ggtgatcgac ggcgtgtcat ggcggattct gctggaagac tttgcatcag gctattcgca
      601 tgccgcacag cagcatgaca ttgtcttccc tgacaaaacc aattcgttta aagactgggc
      661 tgaagcgctt gaggattatg cgcaaaccga acgcttcctt aaaacggccg attattggcg
      721 cagacttgaa caagagcgca tttgtgagct gccgaaagat cgcgctgccg cagaaagaaa
      781 agcagaaaac acctctgccg ttaagtttga attaaacgaa gcggagacgc gtctgctgct
      841 gacgaaagtg catgagccgt atggaacgga tatcaacgac atcctgcttt ccgccctcag
      901 cctgacaatc agggaatgga cgaacgactc caatatttgc atcaatatgg aaggacacgg
      961 cagggaggaa atcattccag ggatcaatat ttcgagaacg gcggggtggt ttaccgcaca
     1021 atatccggtt attttaaaaa acgaagcagc ggcaggattg cctgagacca ttaaaaatgt
     1081 caaagaaacc cttcggcgca ttcctgataa aggaatcggc tacggcatcc ttcgctactt
     1141 aacagaccgg aaaaaagtcg gtgccgattt ctcgatcaag cctgacatca gctttaacta
     1201 cctggggcag atcgacaggg aggtgcagac cgacttcttc gggccttctc cttatgatat
     1261 gggaagacag gtctctgaaa gctctgaagc actctatgcg ctgagcttca gcggcatcat
     1321 cagcaaggaa aaattcatct tgtcatgttc attcaataca gaggaatatg acaggcagac
     1381 catacaggag ctcatggaca gattcaaagc attcctaacg gcattgatcg accattgtac
     1441 agctaaagaa gagcgcgaat ttacaccgag tgatttttct gccggcgatc ttgagatgga
     1501 agaaatgggc gatctgtttg atgtacttga agaaaacttg aattaaccac tgaggacttg
     1561 cccgcttgcc aagcgggcga gcctatgaaa gggggaacga tcttgagcca atttaaaaaa
     1621 gaacatgtcc aggacatata ttatttgtcg ccgatgcagg aagggatgct gtttcatacg
     1681 ctgctgcatc cgggacaagg cttttatatt gaacaaatca gcatgcaggt gaaaggctct
     1741 tttcaaaaaa atgtattgga aaaaagcatg aatgtcatca tcggcaggta tgatatattc
     1801 cgaaccgttt tcgttcatga aaaaatgaaa cgtccgcttc aagtcgtttt aaaggaaagg
     1861 tcatttcagg cagaagaaat tgatctatca ggactttctg aagcagaaca aaacgagaga
     1921 attgaagatt ataaacgaaa agataaagaa aaagggttta acctctcaaa agacattccg
     1981 atgagaaccg cggtttttaa gaaggggcag gatcgttacg aatgggtgtg gagctatcat
     2041 catattcttc ttgacggatg gtgcttcggc attgtcgtac aggaactgtt cgaagtgtac
     2101 caagcgctcc gcgaaaacag gccatacagc ctcgggcccg tcagacctta caaagaatat
     2161 attaaatggc tcgaaagtca ggacaaacaa aaatcgttgt cctactggga acaacattta
     2221 gccggattcg aagggcagac gacgttcagc gaacagcgga aaaaaccgga gcaagccggc
     2281 aatcagccgg aagaactgct gtttaccctt ccaaaagaag atacagaagc gttcacacag
     2341 cttgcaaagg cgcatcatac cacgttgagc acggcacttc aggcggtgtg gtcggtgctg
     2401 ctcagccgct atcagcgatc ccgcgatcta atcttcggta cagttgtgtc aggccgcccc
     2461 gctgacattc aaggtgtcga gcatatggtc ggtttgttta tcaatgtcgt cccgaaacgc
     2521 gtgacctttg acgcgcacac gacctttacg gaacttgtcg ctaatttaca gaagcaggcg
     2581 ctcgaagctg agccgcatca gtatgtgccg ctctatgata ttcaaagtca tatagcagcg
     2641 ccgaacttaa tcgaccacat tatcgttttt gaaaattacc cgctgcaaga agccaacaaa
     2701 cagcaggaag aaaaaaatct cggcttcaca atggacgaga tcagcgtttt tgaaaaatcg
     2761 aattatgatc tgaatttgct cgcctcaccg ggggaagaaa tgctgctgaa acttgcatac
     2821 aatcggaata tctttgagcc atctttcatc ttgcagttaa aagaacagct tttgacagcc
     2881 attcgcgaga tcattagaaa tccggagcag ccgcttgccg acatttgtgt cgtgtccaca
     2941 aaggaaaaag agcgccttct ccatgaattt aacggtcaag ttcaacagaa gcaaaccgga
     3001 ctgacgatcc cgcaatggtt tgagcaatat gctgaagcct tcccggaaca gcccgcggta
     3061 tcagcggccg gacggacgct gacatatcgg gaattgaacg aaaaggcgaa caaagtcgcg
     3121 catcttttgc gcaaaaagaa cgtcggccgc ggcgaacccg tcgctctgtt gttccgccgt
     3181 tcgccggaaa tggtcatcgc actactcgcc gtcttaaaag cagggggcgc ctatctgcca
     3241 attgacccgg aatatcctga agcgcggatt cagtatatgc tgaaagacag cggggctgtt
     3301 tgcatgctga cacaagaaga gcttgccgga cgggcggcgt cgctttcttt tcatcagaat
     3361 acgatcttga tcgacgatcc ggagctctct gctgaaagcg ggcggaacct tgaaatcact
     3421 gccgagccgg atgaccttgc ttatatcatg tatacgtcag gcacaacggg aaaaccgaaa
     3481 ggcaatctga cgacacatgc caatattaca agggttgtaa aagaaacaaa ctacatcagc
     3541 ctttccgaga aagacacctt gctgtccctt tcaaactatg cgtttgacgg cttcacattt
     3601 gatgtgtacg gtgcgctgtt aaacggagca aagctggtgg tggccgatca ggcgacgatt
     3661 ctccatatcg gcaagctgac agaaacgatt cagaaggaaa acatcacagt catgtttgtg
     3721 acaacggcgt tgttcaacct gctggtcgat gccggaacag agtggatgaa agggattcgc
     3781 aaagtcctgt tcggcggaga gcgctcatct gtcagccatg tcaagaaagc atttgctgcc
     3841 atgggaccgg acaaaatcat ccatgtatac gggccgacgg aaacgaccgt cttcgcgacg
     3901 ttctatccgg tcaaccgcat ggaggacagc gcggcttcca ttccgatcgg caagccgata
     3961 aacgaaacga atgcatacat cctgacggaa aataaccggc tgcagccgat tggagcggtg
     4021 ggtgaattgt gtctgagcgg tactggggta tcgcgcggct atttgaacag gccggaattg
     4081 actgcggaaa aattcgcgcc gcatccgttt aacagcggtg aaacgatgta caggacgggg
     4141 gatctggccc gctggctgcc ggacggcaat atcgacttca tcgggcggat cgatgaccaa
     4201 gtgaaaatcc gcggacaccg gattgagctc ggtgaaatcg aagaggaact gctgcgctgt
     4261 caaggcgtaa aggaagcggt ggtaaccgcc aagaaaagcg ggaacgggga tgcggcgctc
     4321 accgcttatg tcgtccctgt aaagggagct gaggttgcaa gcgaggaggt tcgccgccaa
     4381 ttggctcgga agcttccggc ttacatggtg ccggatgcat atatcatgct tgaagagctg
     4441 ccgctcaccg caaacggaaa agtcaaccgc cgccttcttc ctgaagccga tggccggccg
     4501 aattcaacag agcgccgtgc accccgcaat gttacagaag aaaagcttgc ggtgatttgg
     4561 tctgaggttc tcggcagaca gcagatcgga atagacgaga acttttttga aatcggggga
     4621 cattcattga aagctatggc tgtcacctcc cggatgctga aagatctcgc catcgatgtt
     4681 ccggtgaatg tgttgtttga aatgcctaca atcgagggcc tcgcggctta tatcgaccag
     4741 ggcggacata cggatgacgt gaaaaaaacc gtcttcaatc aggaaagcac ccgccatttg
     4801 ttcgccttcc cgcctgtcct cggctatggc atcgtgtacg gcaaactggc cgaacaaatg
     4861 ccggaataca agattcatgc gtttgacttt atagaaagcg atgaccgcgc cgtgcgctac
     4921 gcagaagcca tctccggcct tcagccagaa gggccgctga cattgatcgg ctattcggcc
     4981 ggctgcggac tcgcctttga agtggcgcaa acactcgaaa agaacgggcg gaaagtcgaa
     5041 aagctgctga tgatcgattc atatatgaag aacggtgtca gcgatttaga agggcggtca
     5101 attgaagctg atacagctgc tctgatggaa gccaacaagg acaatgaata tatgaaaatc
     5161 aagacggttg ccgatggcat cgccaaaaag atggcagcct attattctta ctttgttaat
     5221 cttgtccatc aaggaacggt cagctgcgag attcacttga tcaaatcaga gcaggcgaaa
     5281 ccgctcccgg catggctttc gtcttggaaa gaaggaacgg agtcttctta tgatgaatat
     5341 caaggcgctg gaagacatga tgaaatgctt gcggacggct ttgtcaaaac taatgcagat
     5401 ctgatcagac agattttggg cgaacgtgcc gctgtaatcg gaggtgtatg atgcatggac
     5461 gagatcatta agcagtttgg agcgccggca agcggcatgc agttgatctg tttcccgttt
     5521 gccgggggat actcggcatc attcaggccg ctttatgaac atttaaaagc agattttgat
     5581 atgctggcga tcgaaccgcc tggacacgga acaaatcgaa tggcgcttgt cgacaatttg
     5641 gaaaagctcg tcgatctgta tatagcggcg ctcaagccga ggctttcctc ccaattcgtg
     5701 ctgttcggcc acagcatggg cggcatggtt gtttacaggt tggcgcaaaa gcttgaacag
     5761 gaagggatct ttccggcagc cgcggtgatt tcagccattc agccgcctca tattcagcgg
     5821 caaaaggtgt ctcacaaaaa tgatgacgca tttctcgacc atctcatcca gcttggcgga
     5881 atacctcagg aactggcaga gcacagggaa atcatgagct ttttcctgcc gtcattcaga
     5941 gcggactaca gagcgcttga gacgttctgc catatcgatc atacgccgct cagatcgcct
     6001 gttcatattc tgaacggaga tcgtgatgag aaatgcatga aggatgcgct tggctggaaa
     6061 aagtgggcgc gtacgatcga tttccactat ttcaaaggcg gacatatgta tcttttatca
     6121 gaaacggaac aagtagccgc caagatgaaa acgattgtcg cggccagccg cagtacggca
     6181 gttccgacaa tgtaaagaaa acggaaaatc ggtgtgttgc agctgccgat tttccgtttt
     6241 ttcagctttt tttcagccaa ttttcccgcc gaaccatcgt cgctccaatc attccggcaa
     6301 tgatcatccc cgttccggcg aagtgaaacc attcgagaga ttctcccagc catatgatcc
     6361 ccgctaaaat cgtcaccagt gtcgccagat gattaaacat gctgattttc gcagcttcta
     6421 tttttgacag agcataattt gataaaaatg atgtcgcaaa cgatgacatc acacccaaat
     6481 acaaaaccga aagaacaaac accggatcag tgaagggggc aaaaaatccg ctcagcgtgc
     6541 cgtctgacat gtgactgata ccggcgatgc cgttgaaaaa gagaaatccc gcacctgttg
     6601 tcacatatgt taattcaagc gagctgaagg tgcgcgtcat ctttctggcg agcacactgt
     6661 agcccgccga tgaaagcgcc gaaagcaaaa tcagcgccgc ccctctcaaa tcggaacttc
     6721 cgttgcctgc acttttcatc ataaagatgc aggccacccc cgccgcagac aggacggtga
     6781 aaaagaattg ccgcttcgta aaccgctcat ttaaaaaata agcggcgaat atcattgtaa
     6841 agatcgggat cgccgcttga atgataccgg cttcagacga agacgtgtag acgagcccga
     6901 aaacttgaaa agcaaaaaac atgacaggat aaaataatgc taaaggcagc accttcagtg
     6961 cgtcttttat gctgatggcg atcttcaccc atccgagcag aaggggaaag agcgcagcca
     7021 aaaaagcgac cgtaaagcga tgggccagaa tgtcgaccgg actcgctgca gtgagagcta
     7081 atttgacaaa gaaaaaggaa agcccaatga taaaagcata gagcaaagct gccgcataag
     7141 cagttttgtt caaagtcgat catctccgtt gagtatgcat gcaatacaga tattttaccg
     7201 gcttctgtca tcttatacgg aagcgaaatc tgatacaata caaaaaaacg gaatctgtac
     7261 cgttacagat tggcgaagga gacgaacatg cacaaatatg tcgcattgat gaatcaattg
     7321 gaggatatga tcgaagacaa atcctttcag gaaggggaca ggctgccttc catccgcgcg
     7381 ctgtccgtac gcttcaatgt aagcaaaagc acggtcatca gggcgtttaa cgagctggaa
     7441 agacggcacc tcatctattc agtgccgaaa agcggctatt acgtcgtgaa aaaaacgaat
     7501 cagcggtcaa accccggaaa ggccgtgatc gatttcgcag catccgctcc tgatccggat
     7561 gtttttccat acatcgattt tcagcattgc atcaataaag ccattgacac atacaaaaac
     7621 gatctgttta tctatgggac gccgaaaggt cttccgtcat taatcgaggc catacaaaaa
     7681 gagcttgcca acggccaggt gtttgcaaaa gaggaacaca tttttattac atcaggcgtc
     7741 cagcaggctc tcgctttgct cgcttcaatg ccttttccta acggaaagcg taaaattctg
     7801 atcgaacagc cgagctatca cttactgatt caataccttg aggttcacgg catccccgca
     7861 atcggcatcg agagaactgc tgaaggcatc gatatggacg agctggagcg catctttcaa
     7921 accgaagaca tcaaattctt ttatacgatg ccgagattcc acaatccgct cgggacctcc
     7981 tatacggaaa aggaaaaaat ggccatcgtc aagctggcgg agaaatatga cgtctatatc
     8041 gccgaggatg attttttagg agatttggag aatcataaaa aggcggatcc gttacattat
     8101 tatgacgttt cttcacacgt gatttatttg aaaagtttct caaagattat ttttccgggt
     8161 ctgcgggtcg gagccgctgt gctgcccgat tctctgacag atgtgttcaa ccggtacaaa
     8221 cagctgctcg acattgacag ttccatgctg tctcaggccg ctttggagat ctatttgaag
     8281 agcgggatgt ttgaaaagca taagcaaaag attcgttctt cctatcaaaa aagatcatgc
     8341 cttctgcatg atctgctaaa agaatgtgcc gcgtctctag gagatgtgtt tgaatttcat
     8401 cctcccgcac atccggctat ccacacccat atcgaattgg accgaacgat cccggtttcc
     8461 cgtctgatta aaagcataaa aaaacgggac gtcctgctcg aaccggtaaa cgctcattat
     8521 atgtcgacct ttccaaaaag aaatctttta aaaatcaata cgtccaatgt gaaggaagtt
     8581 gacatccgcc gcgggatcga gcgattgcgg caagcggtgg aaaccactta tttttaggcc
     8641 gggacttttt aaagcattga cagttcagcg cagcttttca tcacaatgcg gtcgggaaat
     8701 tcaggcgcgg cggaacacac cgccatctta tagccggggt caatttcata ggcttgtata
     8761 tagcaaggcg gatagcccgg gggagtttcc accgaagcgc gtccctgttc gttcagcttg
     8821 acggagaagg aatcaagcgg cagagacaag ccttttcccg cctgtttgat aaagctttct
     8881 ttcatcgtcc acaaatgata gaaatacgac aggcgttctg attcgtcctt ttccatgaga
     8941 tcatggtgct cggaaggtga aaaaaaacgc ttggcaatgt cgaaattgat cggcttgatc
     9001 atttcgacat ccactccgat cggctgcgtg ccggctccgc acacgatcca ttttccggag
     9061 tgggaaatgt tgaaatgaaa gtcgttcaga ccttcagcag ccggtttgcc gtaccttcct
     9121 tctgtaaaac ggatctgatc attcggcaaa tgaaacgttt cgctgatgat gtgcctcgcc
     9181 agcacttccc cgatcagcgt ccggctggca tcttcgggat atctgtatct gcccactttt
     9241 ttgcgctttt cttcggacac catggccatc attcggttaa attgaccggc ttccggcagc
     9301 tgatccatat aaacggcgta aatcttcatc aaatgcaacc tcttcacatg atattttttc
     9361 tgctttcatt ttagcaaacg ggcagcagga aagataggca tgatactcgt acagaatgga
     9421 ggatgaacat gatagacgga acattgatca aagatacata ctcaggaagg gagcttttga
     9481 tctatcttcc tccttcatac gggagcggtg aaaaccgtta tcccgtccta tacgtacaag
     9541 acctgggaga tttgtttgat ccggcataca gcggcagttt gcgctcaatc gaaaagctgt
     9601 ttttgaatca ggaagtgccg gaattgctgc tggtcggagt ggctccaaaa gacagggaaa
     9661 gcgaatacac cccttttccc aagccgcatt tgctgccgaa taaacgggag tacggcggga
     9721 agggcaacga atatgccgct tttttggcaa atcggctcaa gccctatatc gaccggtact
     9781 accgaacgaa tccaagccgt gaacatacag gaatcatcgg aaagtcgttc ggcggattga
     9841 tctcggttta caccgcttat ttagcatcgg atacctttgg gaaaatcgga tctttgtcag
     9901 ggtctttctg gtttgaaggc atgaccgagt ttatgaagaa taaccgcttt gaaaatgagc
     9961 atatgcgcat ttatatggat gtcggaagca cggaaggggc agacagggat aatctgcaga
    10021 aggagatgat accgaggacg aaggaagcct tcagcctgtt aaccgaaagc gccgcctctg
    10081 aaaaagaact gaaatttgtc attgatgaag gaggctcaca tcggcttgag aggtttgcga
    10141 agcgttttcc ggaagccgtc aaatggctgt tcggctcctg tcacaacagc gcacggaatg
    10201 acaggaattt ctgattggca tgaagtatcg ttgtaaacaa gaggagcgga agcaatggac
    10261 attctgaatc gtttggctga aagcatcgat tatattgaaa agtatttgga tcagccgctg
    10321 aaacacgaag aaatcgccaa gatcgcatac tgttcgaaat ttcattatca gcggatgttc
    10381 tacatgctga cgggtgtcac ccttgccgat tacattcgca aaagaaggct gacagtcgcc
    10441 gcgcaggagc tggctgctaa gtggttgatg ctgcttttaa atacggctac aacacaccgg
    10501 aatcattttt aagggcattc agccgacttc acggcatcag cccttcacag gcccgtgaaa
    10561 aaggccggac actcagggca tttccgcgtc tatcctttca tattcaaata aagggcgtgt
    10621 tgaaaaagaa ccgtttcagg tgatcggcaa agcgctggag gttacggtga aggatgatca
    10681 aaacaaaaag gacattccgg ctttttggaa cgaattaaat cacaacggct ttaccgattc
    10741 tttaaagccg catatcggcc cgctcggctt ccttggcgtc tgcatggatt ttaacgatca
    10801 agccgatacg ttcaattatg tcatcggggt cgaaaaaaca accgctgaca cgcctgccgg
    10861 ctgtgtcgaa aaaccgattc ccgccgcaac ttgggccgta tttgaggcca tcggtcccgt
    10921 caatcctgct gttcaagcca catgggaaag gatcttctca gaatggtttc cggcgacggg
    10981 ctatgaactg gcgaacgccc cgcaatttga atcctgtccg aaagacgggg atattatggc
    11041 gcaagaccac atcaccgaga tttggatacc ggtagtcaag aagaaaatat aaataagaaa
    11101 aacggatgaa acgctcatcc gttttttttc agcgacatat gtacaggctt ggcagctctg
    11161 atacgccttc ctgtcattgc tgcttttaaa agctgtttgg actgcggcaa agaaaaccgc
    11221 aaaatcaggc ctgttaaaat agcggttaaa acagtgccga tgccgatcgg tccgccgagc
    11281 agccagccga tcaataaaat cgtcagctcc attccgttgc ggacccactg aacgttccag
    11341 cccgttttct cggaaatcaa aagcatcagg gagtcacgcg gacccgcccc gagatcggcc
    11401 gacacataaa tgccgactcc gtaaccgata aaaatgacgc cgatcacgaa tacgacagtg
    11461 cttgaaatat acgtttccgg gtctggaaga atataagtaa agaaatctat aaaaataccg
    11521 attaacagca tattaagcac ggcgccgatt ttcggccatg cttttgtaaa taaggacgtt
    11581 aaacctacga tgaccgcccc gacaataatt gcccattggc cgaccgtaag gcccaaaagc
    11641 atatacagcc cgtagtgaaa cgcatcccaa ggaccgatgc cgagcacttt cccttcaatc
    11701 gtaagagaaa ccccgaaaga caaaacaatc aatccgacaa aataaaaaag ccagcgcaaa
    11761 acaagttccc gcttcaatgg attcccctct tttcaaaaaa acaatcgatt gtcattgtat
    11821 cacattcttc agaacggata aatgcggatt tcggcatgtg gctccttaat ttacataatt
    11881 atgattatat tccaattgat gaaaatgatg tatgatagct gtgggatgca ttttccatta
    11941 tggaggggag aaactcagag acttggcagt cgatagtgat ccgggaccat tttatttatg
    12001 tcgacggaag catcatcggc cagtcctatt tggcagagcc gatgggcgaa ccgggagctt
    12061 gggacgttct tgtatgctgg ctctttgttc attgcggttc agcagtatgc agcggaaaaa
    12121 cagcagattt tatgaaaaaa ggaggggaat ggcgttgatt tttttagtta ggctgatctg
    12181 tcttgccttt ttagcctgtc tggcgctgtt gtttatattg aactatgcac cttttctggc
    12241 gatgcccgtt tggatcgctt tgatcattgc cttaatcgtc tgtctgtatc ttgcctttat
    12301 agaggaaatg aaggaatgga gaagacgaaa gcactaatcc tttcttcagc gttttttctt
    12361 gtataaaaga acgtttgcta aaacgaaata gatgacggca gttccggaca caaacaataa
    12421 aaattctttc cactctaatg ccgtcatgta tgcgaagcgg cggagttcga gatgttcatc
    12481 caagtaataa gcctgggtat atgcgccgac tgtcatgccg ataaaggcga atagaccgac
    12541 cacattgaac accattctca tactgaatgt ctttttctct ttttcgtggt tcattttaaa
    12601 gaaatccttt ccaatatgaa tttatcattc tattgtacga atataacgct tggatgattc
    12661 aaaaacttct taatctattg ttaagaagtt tttttatttt ggagaaaatg taaaagataa
    12721 aacaatttca tgaacttttt aagcgaaggc ctaaaaatat aggaatatta taccgatatg
    12781 gcaagtgaaa tctttttctg aaatataaaa gacaaggcag gagagaaaat catgcagcaa
    12841 cgcaatacac cggatgtaca gagatggttt ccaagcgagg acggaaatga agcaaaacga
    12901 aacgaattcc tatcattgat cgagcagctg atcgagggag tggacaagct gaaaaatccg
    12961 gatcaggtca accttgacgg cgagaagaac cgtgagggct tcttttatga aaagctggtt
    13021 gcagacagtc ggattccgta tgaaggtgca ccgatgaaag aggttaacga agagctgttg
    13081 aagctgttgc acggccatcc gtatcacacc aaatactttt tcacgaacat tctgccgatg
    13141 gccagcatcc cggggatatt aggcatgcta acggcgttta tggtcaatgg caacaacctg
    13201 tgggatgtgt acggtccagc cggagcggag gcggaagtga aagttacggc gatgatgtca
    13261 aagcttgcgg ggtatgatgc cgaaacaagc ggaggatata cgacgtgggg aggacaaggt
    13321 gcggtataca gcggtctcag aatcgcgatt gccaaaatgg cgccgtcagc gctgaaggaa
    13381 ggagttcccg gcaatttcta tgcgttttgt tctgaagcgg ctcattacag cttgtataag
    13441 tcgatggaag ctgcaggact cgggagcgat catttaatta aagtcaaaac aaatctcgac
    13501 cattccatgg ataccgaaga tttacgagcg aagcttagaa aagtctgcga agccgggggc
    13561 attcccgttt atatcgtggc tacgacagga acgacagatg cgatcggcat cgatgatgtg
    13621 agcgctgtcc gccgtgctgc tgaagaaacg gcgaaaagtt tcgggctgcc ggttccgcat
    13681 atccacgccg attccgccct aggaggattt tttgcctttt ttaatgagta cgatctgaat
    13741 gagaacgctt tatccttcag tcccggcgtc ctcagcatga tcaaaccgat tcaggaaaaa
    13801 atgagacatc tgcatgcagc cgattcgctt tgctttgatt ttcagaagct cgggcagacg
    13861 ccttatgtga caagcctgtt tcttgtgaag gatcgcaatg acttaaaacg gatcgatctg
    13921 gatcctgatg agacgccgta tgtcggccac cgcggctatg gggactacca tacgggctac
    13981 acgctggaat gttcgcgcat ggccagttcg atcagtatgt acagcgcgct gatggcattt
    14041 ggctatgaag gctatcaaaa gctgctcgcc cagttccttg aagtcaacct gcattttagg
    14101 gaacagctgt ctcagcagat tccggaagcc gatattgtga acccggacaa ctgcggcatg
    14161 tctacgctgt ttcgcattta tcctgaaggt gcgccgagat ttgaagacga aatttcggga
    14221 gcatgcacca ttcaagagct tgaaagaaac aatgcactca ctgaaaaatt atttgagaag
    14281 ctcggaacaa aaagggacaa gatgtttttt ggcgatacga aaaaacactt gcttgtgaag
    14341 tcctgtgaag ggactgagac accgctttgc gtcagcaaat ttttcgtcat ttctccgtat
    14401 accatgcctg aacatgtccc gggaattatc gattatttaa aagaaaatat taaggaagtc
    14461 tgccgggagt atggatctct catgacaaat taaaggggat atagacgatg aaaacgttga
    14521 agaaaaagct aacagaacac atttcagtca aaattatgat tggcgtcgcc ttagtgcttt
    14581 tgatcacgat cgcatcattt tcagctgtgt ttacttttat cagtaaagac ttgtcagagc
    14641 agctgaaaca gcagttccaa aaccgccttt ataccgatat tcatcttgct gaaaaccaaa
    14701 tcaagcgtct ggacgggaat ccgcttgaga tcgattccgc agataacccg ctttacaagc
    14761 agacaaaaat ggctgtggac agcctgaaaa agaaaaacaa acttgagaat atctatatcc
    14821 tttccaatga gggcgggaag gagcggattc tcgtgctgtc ggatacgtcc gatgatttcg
    14881 gcacggatta cagcttttct cccgaaatga aagaagcttt gacgacaaac aaagagacag
    14941 taagcgatgt gtatgaggac gaatacggca tccaccagtc aatttttctg ccgcttgaga
    15001 acggctcagg cgaaaaggtc ggaattttgg ggatcgacct tgatgcttcc gtgattccgg
    15061 cgacagcggc aaaagcgaaa tggtatacaa ttgcgatctc agcatttgtt ttgctgcttg
    15121 gcatggtcat ggcttatttg ctcggttctt acatcgcgaa gccgatcagg cagctgatga
    15181 aggcttcaga aaaaattgcc gacggcgatc tatcggctga catttccgtc aagagccgtg
    15241 atgaagcggg aaaactcgca gaatcattca agcggatgag cgaaaattta caacaattga
    15301 tcggacatat ttcagcttcc tctgaagaag tatccaagac gagcctccag ctgaaaaatg
    15361 tatccgctga atcgagcgaa agcgcagtcc aggtggctga atcgatgaac agcatgagcg
    15421 agggaatcaa cgaagttgtc tcttccgttt cggattgcca tacatcggct gccgaaatcg
    15481 atcatcagct ttcacatgtc acagaagaag taaacgagat gaagaacgtt gccgaaggcg
    15541 taagcaagga ttccaagaca gggcaggagc ttgtcggaga aacattgcgg cagacccaga
    15601 cgattaaaaa cgtgatggaa gagtccaaac aagcggcagc agagatgcaa aaccatactg
    15661 aagaaattga aaaagtcatc ggtatgattt cctctattgc cgaacagacg aatttgctgg
    15721 cgctcaatgc ttccattgaa gccgcccggg tcggtgaaga aggtcagggc tttgcggttg
    15781 ttgcgggaga agtcagaaag ctttctgaac gctcggcaga tgccgcttta tccgtttccc
    15841 agcttgtagc gggcacgcag gagagcagcc ggctcgtcat ggaacgcatt caggaaggaa
    15901 acgaagcggt tgacaaaggg cagattttaa tcaatggcac atacgagaat ttttcaggaa
    15961 tttttaaagg gatctctcaa tttgccgaac gcaccgatca attgctgcag tctttgttaa
    16021 aagtcgaaaa atcgtatcaa aacatttcgt ctgcgatgga gcagatttcc tccgttaccg
    16081 aagagcaagc ggcaggttct gaagaagtcg cggctgcagc ggagcagcaa agcgccggca
    16141 tgcaggaaat cgcatcggcc attcagcagc tttccgcttt gtcggaagaa ttgaatcaag
    16201 cggcatccaa gtttaaatta gccgctgaat aaaaagaaca gcctgatccg gagagatcag
    16261 gctgttttgt ttatacagga ttcaaaatcc ggtttaaaaa ctgttttgtt cgctcttcct
    16321 taggggctga gaaaatttgt tcaggcggac cctgttcgac gatgacgccg ccgtcgataa
    16381 agacgacttc gtctgcgaca tcctgcgcga atttgatttc gtgggtgacg acaaccatcg
    16441 tccagccctc attcgcaagg tctttcatga ctttcagcac ttcaccgaca agctcggggt
    16501 caagcgctga tgtaggctcg tcaaaaagca tcagttcagg cttgatggca agggcacggg
    16561 cgatgccgac gcgctgctgc tgtcccccgg aaagctggaa tggatagagg tccattttgt
    16621 cttcaaggcc gaccttttgc agcagctgaa cagcttcctt tttgacttcc tgtttattgc
    16681 gcttttgcac ttttacaggc ccttccatca cattttcgag cacggttcgg tgcgggaaca
    16741 ggtgataggc ctggaatacc attcccgact ttctccgcag gcggaggagg tcagccggtt
    16801 tatttttctt ggaaaagtcg atggtgaaat cgtcaaaaga aagaatgccg cggtttggag
    16861 tttccaaagc gttcaggcag cgaagcagcg tcgtcttgcc ggaaccggac ggccctaaaa
    16921 tggcgatcac ttttcctttt tcgatgttca gatcgatttt ttttaagatt tcattttcgc
    16981 cgaaggattt attcagccct ttgatcgcaa gcatggtcta tttccctcct tacttggcca
    17041 cataccggtc caaccgccgt tcaatctgct gctgaacaag cgcgagaaca aagcagatga
    17101 tccaatagat gaatgcggct tccatataaa tgattaaaat ttggtcaagg ttgctggccc
    17161 cgatttcctg agctttccgg aataattcag caacaagaat ctgtgacgca agcgatgtgt
    17221 ctttaaccaa gctgatgaat gtattggata atggcgggat cgacacgcgt acagcctgcg
    17281 gcaggatgac cctggtaagc gccgtttttt gagtcattcc aatcgaataa gccgcttccc
    17341 actgtccttt cggaacggaa aggatggaag ccctgatgat ttccgacgca taagcgccga
    17401 catttaatga aaaggcaatg attgcgctcg gaaacgggtc aatcgtgatt tgaaacgcag
    17461 gaaataagta aaaaatgatg aacagctgaa cgagcagcgg cgttccgcgg atcgctgaga
    17521 cataaatgcc gaaaaccgct cttaaaatgc gggatttgga cattctcgcc agcgccgtga
    17581 tcaatgcgat gatcataccg aatataaaag agagaatggc aaggggaatc gagtaataga
    17641 ttccccttaa aaagatcggc caaaatgact cacgcacaag atcccacggg atcgccgcgc
    17701 cgatggccgc cgcttgtata ttacttagaa acatcttcgc caaaccattt cttcgctatt
    17761 ttcgcgagtg tgccatcctc tttcatgtct ttcagcgcgg agttgacctt gtcaaccagc
    17821 tcgccgcttc ctttgcggaa agcaaaatgc gtagtttgcg gctcgcctgt ttcaaaagcg
    17881 actttcaggt ttttgtttcc tgatgtcttc aaatagttca gcaccgccag tttatcgtta
    17941 aaggtaaggt cgacacggcc ctgctgaatc agctgaaacg cctgagccat tccttccacg
    18001 ccttcgattt cagcgccggc gtttttcgca aggtcattat agttgcttgt caaagactgt
    18061 gcagcttttt ttcctttgac atccccttca gactttacat cgttgttgtc cgcttttgtg
    18121 acaacgacgg cttgggaagt tgtatatgaa tcagaaaaat cgtactgatc ttcacggtct
    18181 tttttcccga cttggttggc aacgacgtca aaacgcttgg agttgagtcc ggcaaacatg
    18241 ctgtcccact gcgtttcttt aaattcaact ttcaggttga ggcgtttggc gacttcctgc
    18301 atcacttcga catcataacc tgttaattta tctgtttttt tatcgtggaa tgtaaatggt
    18361 tcgtacgttc cttcagtacc gacggtcaat acgcctttat ctttaattga agaccagagg
    18421 ctgtcgccgg ctgcgttttt atccttggaa ttgtcccctg acgcgccgca tgcggccatc
    18481 acggtgatca acagcgtcag taatacagcg aatatggctt ttttcatttt attccccact
    18541 tttctgattg gatttagttg atatgatttt acttaaggct cttacaaaag taaagcataa
    18601 acctttttta gtatgagtca agaaatacgt ttttagtgat gaaagggaga gaagatcatt
    18661 ctggctcctg atcaaagcgg atcttccatt ttttaagcct gtattgcaga ctctgcctgc
    18721 tgatccccag aacccgagcc gcttgtgaca cattgtaatt gcatttttta acggtttttt
    18781 gaatataata cttttcggca ttctcgattt gttcctttaa aggagcggct gaggcggaag
    18841 gaagcggggc gaacagatca tagccctgct gcggcagctg ttcttttgcc gctggtttcg
    18901 tcctgtattg caatggaagg tgtgtcagct ccattttgtc ttcgtaggac atcaaattca
    18961 tggcgccttc aattaaatgt tcaagctccc tgacgtttcc cggccaatcg taagaaagca
    19021 gaaaccgccg cacatcttct tcaaaaccct tgacctccat ttggaacaat gcgttgtatt
    19081 tgtcgataaa atgctgcgtg agcggcatga tatcttcctt tcgttctttt aatggaggaa
    19141 tgaacaaggt gacgacgctc agcctgtaat acaaatcttt tcgcagcctc tggccgctga
    19201 ccgcgtcgac tggatcttcg ttcatcgtcg cgatgatcct gacgtcgatc ggagtatcct
    19261 tcgcagcgcc aatccgcctg atcgtttttt cttgaatcgc gcgcaaaagc tttgcctgca
    19321 aactgaagtc caaagaattg atttcgtcaa ggagcagtgt gccgccgtct gcttgttcga
    19381 aaagacccgg gcgatcgacg gctcccgtga atgcgccttt gaccgtgccg aataaaaggc
    19441 cttcgacaag gcttcccggg agggctgcgc agttttgcga gatgaatggg cccgtcgagc
    19501 gctggcttcc gttatgtata ctttgggcga acagttcttt tccggttccg gtgtcgccaa
    19561 cgatcagaat ggatgaagag gtccgggtcg cccgttttgc atgttcaatg acttccttga
    19621 acgccggact gacgccgatc agactgtcga aggtatactt tgtgttttct gttttgttca
    19681 tattttctct gatcaggcgt tcaagctttg tgacatcttt ggcaatctca accgctcctt
    19741 tcgtattccc gttttccata atgggaaacg tatgattgac ggtcgtaatt tcctggcctt
    19801 tgttattgaa gtaagtctgc ttgacgtttt tgttcgtttt cccgtgatgc agtgcctgca
    19861 ggagagtgct gtcatgctgg ctggcaaacg taaacacgtc cagcacgttt ttgccgagca
    19921 catcgccgac atccatccct tcaatctggc tcattttttt gttatagaca acagatgtac
    19981 cgttttcatc gacgacatgc aagccgatat cgatttcatc tataattctt tgaaaaataa
    20041 acttcagtaa atcgtaatcc ttcagcaagt gacatccccc tttgttcgtc tctgtctcca
    20101 ttttaagtga agacttgata aaggtgcaaa aaaatatgca tttatttttg cacctttgaa
    20161 taaaaaccgc aaaatttttt gcgcgttata catgcaatgt tctgaaaatt tgcggtttta
    20221 aggattggca cgatacttgc atataagata gtgtgaaaca aaatacgaca tctggcatgt
    20281 atgtccaaaa ataagaagga ggaatcagaa tgacggttct atcaaagtcc gagaaaatta
    20341 tgaagcaaac cgcacatttt ggcgcgaata actatcatcc tctgccgatc gtgatttctg
    20401 aagcggaagg cgcgtgggtg aaagatccgg aaggcaaccg ctacatggat atgctgagcg
    20461 cttattccgc agtgaatcaa gggcacaggc acccgaaaat catccaggcg ttaaaagatc
    20521 aggccgacaa aattaccctg acttcgagag cttttcacaa tgaccagctt ggtcctttct
    20581 atgaaaaggt cgcttcatta acagggaaag atatggttct gccgatgaac accggggcgg
    20641 aggcggttga gtccgcgatt aaagcagccc ggcgctgggc ttatgatgta aaaggcgttc
    20701 cggacaatca ggcagaaatt atcgcatgtg aaggcaattt ccacggccgg acgatgctgg
    20761 ctgtgtcgct ttcttcagaa gaagagtata aacgcggttt cggaccgatg cttcccggca
    20821 tcaagctgat tccatacggg gatctggagg cgctgaaaca ggcgatcaca ccgaatacag
    20881 ccgctttctt aattgagccg attcagggtg aagcgggcat tgtcattccg ccggaaggct
    20941 ttttgaaaca ggcagcagaa gcctgcaaag aacgcaatgt cttgtttatc gccgacgaaa
    21001 tacagtcagg gcttgcacga acaggcaaaa tgttcgcctc tgattgggag gatgtcaaac
    21061 cggacatgta cattttagga aaagcgctcg gaggcggcgt gttcccgata tcgtgcattg
    21121 ctgcaaaccg ggatgtgctt ggcgtgttta atccgggctc gcacggatcg accttcggag
    21181 ggaacccgct tgcatgcgcc gtatcgatcg ccgctcttga agtgctggaa gacgagcggc
    21241 tcgctgaacg gtcgctggag cttggggaat attttaaaga aaagctctca caaatcgata
    21301 atcctaaaat taaagaagtg cgcggcagag ggctgttcat cggggtagag ctgaccgagg
    21361 cggcgcgtcc gtattgcgag cgcctgaaag aagaagggct gctctgcaaa gaaacgcatg
    21421 agacggtcat tcgctttgca cctcctcttg tcatctcaaa tgaggatctg gattgggcga
    21481 ttgaaaagat tacccgtgtt ttgtcgaagt aaagcgaacg gctgaacaat gaggggattg
    21541 ttcagcccgt tttttcgccg gctgtgcgaa gtttgtcaaa aattgaaata tcaggaaaat
    21601 gttcagaaga tttaaaaaat agtctatatg tcataggggg agctgacatt agggagaatg
    21661 gaaacggaag gggtgaaggc ggtttgaatc atgaaaaccg tgaacaatat acactgaaac
    21721 gaacgatgaa atcccgccat ttgtttatga tctcgcttgg cggcgtcatc ggaaccggct
    21781 tttttctcgg aacaggatat acgattaatg aagccggacc aatcggcgcg attctttcct
    21841 atttagcggg cggaatgatc atgtatttta cgatgctttg cctcggggag ctcgcagtgg
    21901 caatgccggt ttcaggctct tttcagacgt acgcgacaaa atttatcggg cctgctacag
    21961 ggtttgccgt cggctggatc tattggctcg gctggtcggt tacggtcgct ttggaatttc
    22021 tgtcagcggg gcagctgatg aaaagatggt ttcccgatgt cggcgtctgg atatggtgtt
    22081 tgattttcgg actgctgctt ttttcactca atgcgctatc ggcaaaggcc ttcggggaat
    22141 cggaattttg gctgtccggc atcaaaatta tcgtcattct tctgtttatt attctcggcg
    22201 gaggcgcgat gttcggactc atcgatatga aagacggaca ggctgcaccg ttcttttcca
    22261 atctgattgg agacgggatt tttccaaatg gattcggcgc gatctttatc acgatgatca
    22321 ccgtcaactt tgcctttcag gggacagagc tgatcgggat cgcggcgggg gaaagcgaaa
    22381 atccggaaaa aacggtgccc cgctccatca aacagacggt ctggcggaca ctcgtgtttt
    22441 tcggcctgtc cgtatttgta ctggcggggt tgattccatg ggaaaaagcg ggggttgttg
    22501 aaagcccgtt cgttgtcgta tttgaacaaa ttggtattcc gtatgccgct gatctgatga
    22561 actttgttat tttaattgct ttgttatcgg tggcgaattc gggtttgtac gcatcgacga
    22621 ggatgcttta ctccctggcg aaagaaggaa tggccgctca ggctttaagc cgtgtcaata
    22681 aaagaggaat tccgatgaat gcgctgtgga tcacgctcgg ttttgcgggt ttgtccctcg
    22741 tttcaagcgt agtcgccgca gaaacgctct acatctggct tttgtctctt gccggtttaa
    22801 gcgcacaagt cggctggatc acgattacgg tatcacagct gctatttcgc agacgatatg
    22861 tcaaagaagg cggtaaggta gaagacttga aatttaaaac gcctctttat ccttatttgc
    22921 cgctggcggg ctttatttta aacagcgccg tccttgtgag ccttgccttt gattcagagc
    22981 agaggatggc attgtactgc gggattttat tcatgtcagc ctgctacttt gtttatcacg
    23041 tatttgtgaa aaaacgacag gctctagagc gacaagaaac aatgatctat caaaacaaaa
    23101 cgaacgatga ggtggttatt gatgaataaa caagtttctt tgattggaat gccgatggac
    23161 ttgggacagg cgcggcgcgg tgtggatatg ggaccgagcg cgattcgcta cgctcatatc
    23221 gtggagcgct taaacgagct gggctatgat atcgatgatc tgggcgatgt gccgatcaac
    23281 cgcgatcagc caaaaggaga tgaagggctg aaaaatttag tttccgtact cgaaggaaac
    23341 cgcaagctgg ctgacattgt tgacaatgtc gtcgagcagc gccgcttccc gctcgtgctg
    23401 ggcggagacc acagcattgc catcgggaca ttggcggggg ttgccaagca ttatcaacag
    23461 ctcggcgtga tttggtatga cgcacacggc gacttaaata cgctggagac atcgccgtca
    23521 ggcaacatcc acggtatgcc gctggcggta agtctcggtg tcggccacga aaagctggtc
    23581 aaccttcacg gctatgcgcc gaaaatcaag ccggagcatg tcgtcatcat cggtgcgcgc
    23641 tcgcttgatg aaggagagcg caaatatatc cgtgaaaccg gcatgaaagt ctatactatg
    23701 catgaaatcg acagactcgg catgacaaag gtgatagagg aaacgatcga gtatctctca
    23761 gcaaattgtg acggtatcca tctgagcctt gatctggacg gtcttgatcc gagcgacgct
    23821 ccgggagtcg gcacccctgt cgtcggaggc atcagctaca gggaaagcca tttggcgatg
    23881 gaaatgcttt atgatgcaga tatcattaca tctgccgagt ttgttgaagt caacccgata
    23941 ctggatcaca aaaataaaac cggtgaggcg gccgtcgaac tgatcgaatc gttgttaggg
    24001 aagaagctgc tgtaactaac gcaaaggaga aggcatcggc atgatgcctt ctctttttta
    24061 ttgacgggtt cccggccgct tatcaaaata aagccaaaaa ttctcttacg ggcttcggca
    24121 gaaaactgcc ggcccgccaa acgacagacg gctgcagaat gaacggattg tcttgaatct
    24181 ccaacgtctg aacatgccgt gcgaaatgcg ccggcagcat ggacagcggc agaattgtcg
    24241 ctccgaatcc cgaagtgacg aggctgagca gtgttgtaga atcatggcac tcacagacga
    24301 ccctcggttc aaggtctgat gattgaaagt gatggaccac ctcgtcgtaa atcccttttc
    24361 cgtgcgacgg cctgaggaga atcagcggca ggccggcaat ttctttcatt ccggcttccc
    24421 cttttaagcc atacgactga ttccccggaa gaacgagctt gcatggaacc tccggcaggc
    24481 tttttgattc gatatttttg ctgtgaaaag gcgttgtcgt gaccgccgca tcgatctgcc
    24541 ggctttccag gagctcgctc agccgtgaag gctcaccttc ccaaatgtta aacattaaat
    24601 tcggatacat gtctctgatc ttcgagactt ttgcgagcag cagggccgcg cagtaaatcg
    24661 ttgagccgac ggcgagggtt ccgttgactt cttcacgcag ctcccgaacc tccaagatgg
    24721 aatcctcaag cttgtgcagg atttcttttg ctcttttcaa aaacacttct ccttcatagg
    24781 tcagcgtcag gtttttcttt ttgttccggt caaataaaac gaccccgagc tcctcttcca
    24841 tctgcttcaa ctgtctggag agcggcggct gtgcgatatg gagccgcttc gccgccgttg
    24901 taatctttcc ttcctgtgcg atcgtaacga agtactttaa ctggcgaata tccattttct
    24961 cggcactcct ttttatacct ttaaagtatt atatatagat ttaacagata ttttcaatat
    25021 ggtaaataga ggcgtatcat tttaactgaa gcaccaagag ggaaaggggg gcgcatatga
    25081 acatcatcgt cggaatcacg ggcgcgaccg gcgcgatatt tggcgtgcgg atgctggagt
    25141 ggctgaagaa aaccgacgca gagacacacc ttgtcatctc tccgtgggca gcggcaacca
    25201 tcctgcacga aacgggatat acgatgaaag acgtggaaaa gctcgcatct tttacatatt
    25261 cccacaaaga ccaggcagcc cgcatatcaa gcggttcctt tcaaacggac ggaatgattg
    25321 tcgcaccgtg cagcatgaag acgttggcgg gcatccgcac cggtatggcg gataacctgt
    25381 tgacccgttc ggcggacgtc atgctgaagg aacgaaaaaa gcttgttctg ttaacaaggg
    25441 agacgccgct g
//
