LOCUS       NZ_JALAJD010000002     22734 bp    DNA     linear   CON 23-JAN-2024
DEFINITION  Bacillus haynesii strain S4B4I contig_0000002, whole genome shotgun
            sequence.
ACCESSION   NZ_JALAJD010000002
VERSION     NZ_JALAJD010000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus haynesii
  ORGANISM  Bacillus haynesii
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 1033027)
  AUTHORS   Dunlap,C.
  TITLE     Crop Bioprotection Bacillus Genome Sequencing
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1033027)
  AUTHORS   Dunlap,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-FEB-2022) CBP, USDA-ARS-NCAUR, 1815 N. University St.,
            Peoria, IL 61604, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC NGS Cell v. 21
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 186.61533326734113x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/23/2024 03:14:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,325
            CDSs (total)                      :: 4,234
            Genes (coding)                    :: 4,160
            CDSs (with protein)               :: 4,160
            Genes (RNA)                       :: 91
            rRNAs                             :: 5, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 77
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 41 of 74
            Pseudo Genes (incomplete)         :: 45 of 74
            Pseudo Genes (internal stop)      :: 10 of 74
            Pseudo Genes (multiple problems)  :: 19 of 74
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:38:58
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 324741
            Orig. end                         :: 347475
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JALAJD010000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22734
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="1"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22734
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22734
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12734](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12734
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            complement(683..997)
                     /locus_tag="MOB25_RS02675"
                     /old_locus_tag="MOB25_02670"
     CDS             complement(683..997)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003186216.1"
                     /locus_tag="MOB25_RS02675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_02670"
                     /product="DUF485 domain-containing protein"
                     /protein_id="WP_268300714.1"
                     /transl_table=11
                     /translation="MREGKIDYSKAAASPEFQLLLKRKRAFIVPMTIFFLLFYFLLPVM
                     TSYFTFLNQPAVGAITWAWVFAIAQFVMTWTLCIVYTRKAGQFDQIASDFKKKIGGVDS
                     "
     gene            complement(1173..1736)
                     /locus_tag="MOB25_RS02680"
                     /old_locus_tag="MOB25_02675"
     CDS             complement(1173..1736)
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009329825.1"
                     /locus_tag="MOB25_RS02680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_02675"
                     /product="flavodoxin family protein"
                     /protein_id="WP_076788283.1"
                     /transl_table=11
                     /translation="MGIAAICGSSRENGNTEELVNRLVDGLDTDKIYLRNYHIEPVSDY
                     RHSNTAPFYPDDDYRNLISRVLEKDILIFATPIYWYGMSGLMKNFIDRWSQTLMEHGRS
                     AFKQEMAKKTVYVAAVGDDDPRLKGLPLIQQFQYIFDFMNMTFDGYLLAKGNKPGGVMT
                     DRAAIVAANELRRKLTESEAGRKA"
     gene            complement(2279..2428)
                     /locus_tag="MOB25_RS02685"
                     /old_locus_tag="MOB25_02680"
     CDS             complement(2279..2428)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003186207.1"
                     /locus_tag="MOB25_RS02685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_02680"
                     /product="anti-repressor SinI family protein"
                     /protein_id="WP_003186207.1"
                     /transl_table=11
                     /translation="MNTQTKHKLDKDWVILMKEAKKLGLQIEDVKEFLRSQPIQSDAEK
                     QIKQ"
     misc_feature    complement(2726..2740)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.3"
                     /tool="antismash"
     misc_feature    complement(3159..3173)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.5"
                     /tool="antismash"
     gene            3231..4220
                     /gene="galE"
                     /locus_tag="MOB25_RS02690"
                     /old_locus_tag="MOB25_02685"
     CDS             3231..4220
                     /EC_number="5.1.3.2"
                     /GO_function="GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (64-191). E-value:
                     1.3e-11. Score: 36.0. Matches aSDomain:
                     nrpspksdomains_MOB25_RS02690_NAD_binding_4.1"
                     /codon_start=1
                     /gene="galE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003186203.1"
                     /locus_tag="MOB25_RS02690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_02685"
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="WP_268338000.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 5.4e-17, bitscore:
                     57.7, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.7e-14,
                     bitscore: 49.5, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAILVCGGAGYIGSHAVAELLSRNEEVVIIDNLQTGHEEAALKGA
                     SFYNGDLRNEAFLRKVFQENDIEAVMHFAADSLVGESVTDPLKYYDNNVYGAVCLLKVM
                     KEFDVKQIVFSSTAATYGEPDRVPIMETDPTDPTNPYGETKLAIEKMLKWSEKAYGIRH
                     VVLRYFNVAGAHVDGLIGEDHQPETHLIPIILQVALGKRDKIMIFGDDYPTPDGTCIRD
                     YIHVMDLVDAHILAVERLRNGGESAVYNLGNGTGFSVKEVVETARKVTGCPIPAEVAER
                     RAGDPAQLIASSEKAVKELGWQPKYAKLETIIDSAWKWFKAHPNGYQS"
     aSDomain        3423..3803
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOB25_RS02690_NAD_binding_4.1"
                     /evalue="1.30E-11"
                     /label="MOB25_RS02690_NAD_binding_4.1"
                     /locus_tag="MOB25_RS02690"
                     /protein_end="191"
                     /protein_start="64"
                     /score="36.0"
                     /tool="antismash"
                     /translation="NDIEAVMHFAADSLVGESVTDPLKYYDNNVYGAVCLLKVMKEFDV
                     KQIVFSSTAATYGEPDRVPIMETDPTDPTNPYGETKLAIEKMLKWSEKAYGIRHVVLRY
                     FNVAGAHVDGLIGEDHQPETHLI"
     misc_feature    complement(4337..4352)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 23.11"
                     /tool="antismash"
     misc_feature    4527..4542
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 23.79"
                     /tool="antismash"
     misc_feature    complement(4549..4564)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: strong, score: 27.5"
                     /tool="antismash"
     gene            4692..5660
                     /gene="qoxA"
                     /locus_tag="MOB25_RS02695"
                     /old_locus_tag="MOB25_02690"
     CDS             4692..5660
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_function="GO:0016682 - oxidoreductase activity, acting
                     on diphenols and related substances as donors, oxygen as
                     acceptor [Evidence IEA]"
                     /GO_process="GO:0015990 - electron transport coupled proton
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene="qoxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003186201.1"
                     /locus_tag="MOB25_RS02695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_02690"
                     /product="cytochrome aa3 quinol oxidase subunit II"
                     /protein_id="WP_154998719.1"
                     /transl_table=11
                     /translation="MILLFRAFKPLIMLTLLSSVFLLGGCSQIAVLDPKGPVASQQRDL
                     ILLSIGFMLFIVAVVFVLFTVMIVKYRERKDRKSPYSPEVEGNTFLEIVWTVVPILIVI
                     ALSVPTVQTIYSLEEAPKASKDKEPLVVYATSVDWKWVFSYPEQDIETVNYLNIPTDRP
                     ILFKISSADSMASLWIPQLGGQKYAMSGMEMEQYLQADHEGTYKGRNANFTGEGFAEQQ
                     FNVNAVSESKFNDWVKKTQKEAPKLTKNQYDELMLPQHADEMTFSSTHLKYVNHGNDAE
                     YAIKARERLGYKPVSPHSKSDPFEDVKTNKDQKQSEDQDSH"
     gene            5678..7627
                     /gene="qoxB"
                     /locus_tag="MOB25_RS02700"
                     /old_locus_tag="MOB25_02695"
     CDS             5678..7627
                     /GO_function="GO:0004129 - cytochrome-c oxidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0015990 - electron transport coupled proton
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene="qoxB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391695.1"
                     /locus_tag="MOB25_RS02700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_02695"
                     /product="cytochrome aa3 quinol oxidase subunit I"
                     /protein_id="WP_154998677.1"
                     /transl_table=11
                     /translation="MNLKWDEFIITGDPLILGAQISILLTSIAIVFVLTYFKKWKWLWR
                     EWITTVDHKRLGIMYLIAAVIMFFRGGVDGLMMRAQLTLPNNGFLDSNHYNEVFTTHGT
                     IMIIFMAMPFLIGLMNVVVPLQIGARDVAYPYLNNLSFWTFMVGAMLFNISFVIGGSPN
                     AGWTAYMPLAGNELSPGPGQNYYLLGLQIAGIGTLLTGINFMVTILKMRTKGMTLWRMP
                     MFTWTTLITCVIIIFAFPVLTVALALMTFDRLFGTAFFTLANGGMPMLWANLFWIWGHP
                     EVYIVILPAFGIFSEIIATFARKQLFGYKAMVYSIVAISVLSFVVWLHHFFTMGNSAAV
                     NSFFSITTMAISVPTGVKIFNWLLTLHRGRIKITTPMLWSLAFIPNFVIGGVTGVMLAM
                     AAADYQYHNTYFLVSHFHYVLIAGTVFACFAGFIFWYPKMFGHKLNERIGKWFFWLFMT
                     GFNICFFPMYFLGLQGMPRRIYTYGAEDGWTALNMIATFGALLMAAGFIVLCYNIFYSF
                     RHSKREESGDAWGMGRTLEWATSSAIPPHYNFAVLPEVTSPDAFAQMKEDNVEIHPESK
                     FKKIHMPSNSGRPFIMSLCFGFAGFGLVFEWFWMGIVGLIGVFLCMILRSFEYDDGYYV
                     SVEEIKETERKNAK"
     gene            7642..8256
                     /gene="qoxC"
                     /locus_tag="MOB25_RS02705"
                     /old_locus_tag="MOB25_02700"
     CDS             7642..8256
                     /GO_function="GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_function="GO:0016682 - oxidoreductase activity, acting
                     on diphenols and related substances as donors, oxygen as
                     acceptor [Evidence IEA]"
                     /GO_process="GO:0015990 - electron transport coupled proton
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene="qoxC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391694.1"
                     /locus_tag="MOB25_RS02705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_02700"
                     /product="cytochrome aa3 quinol oxidase subunit III"
                     /protein_id="WP_216929955.1"
                     /transl_table=11
                     /translation="MEHAEHSNSNAPMEYRSETGRLNILGFWIFLGAEIALFSTLFATY
                     AVLHNRTAGGVLPAELFDAKLVLIMTFLLLTSSFTCGIAVHEMRRGSLKGVMIWMIITL
                     LLGAGFVSYELYEFNHYVHEGATLSTSAYWSSFFVLLGTHGLHVSIGIFWIIGILLQTK
                     KRGLTPQTSAKLFISSLYWHFLDVVWIFIFTGVYLIGLVNV"
     gene            8256..8621
                     /gene="qoxD"
                     /locus_tag="MOB25_RS02710"
                     /old_locus_tag="MOB25_02705"
     CDS             8256..8621
                     /GO_function="GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_function="GO:0016682 - oxidoreductase activity, acting
                     on diphenols and related substances as donors, oxygen as
                     acceptor [Evidence IEA]"
                     /GO_process="GO:0015990 - electron transport coupled proton
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene="qoxD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006639513.1"
                     /locus_tag="MOB25_RS02710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_02705"
                     /product="cytochrome aa3 quinol oxidase subunit IV"
                     /protein_id="WP_176276799.1"
                     /transl_table=11
                     /translation="MAAKQSAEHSHFPWKHIVGFVLSIVLTLLALWVIYTDLSMAAKLW
                     IIFGFAIVQAGLQLLMFMHMTESDSGKIQVGNTLFAAFIAVAIIAGSVWIFAAHNYHGD
                     NPEGGSPGAKHSEHSGH"
     CDS             complement(8721..8846)
                     /gene="allorf_0333462_0333587"
                     /locus_tag="allorf_0333462_0333587"
                     /protein_id="allorf_0333462_0333587"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MTQMRKLESAQVKNYGTFLTVTLSKKSKPGDGKFGRGVKRG"
     CDS_motif       complement(8778..8846)
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MTQMRKLESAQVKNYGTFLTVTL"
                     /locus_tag="allorf_0333462_0333587_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       complement(8721..8777)
                     /prepeptide="core"
                     /locus_tag="allorf_0333462_0333587_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="-7.30"
                     /molecular_weight="1871.1"
                     /monoisotopic_mass="1870.1"
                     /core_sequence="SKKSKPGDGKFGRGVKRG"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MTQMRKLESAQVKNYGTFLTVTL"
                     /leader_location="[8777:8846](-)"
     gene            9009..9641
                     /locus_tag="MOB25_RS02715"
                     /old_locus_tag="MOB25_02710"
     CDS             9009..9641
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003186191.1"
                     /locus_tag="MOB25_RS02715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_02710"
                     /product="response regulator transcription factor"
                     /protein_id="WP_020453360.1"
                     /transl_table=11
                     /translation="MIRVLLVDDYRVLTSGMKEILKKYNMDVIVCHEGNEALDLLKNQE
                     VHIDVFLYDLKMPGMNGLELSLKTLEIAPQSKIIIMFSGDEIHSYFNKLIEAGVKGFID
                     KSYTDSMIASSILLCLKGAVLFPDGLLQKLRLDSDLAVDEHLTDTELDILQKVASGKTN
                     KEIAADLQMSTRNVEYHLSKIYKKLKVTSRYCAVKKGTMLNLIKQKA"
     misc_feature    complement(10000..10018)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 23.74"
                     /tool="antismash"
     gene            10001..10273
                     /locus_tag="MOB25_RS02720"
                     /old_locus_tag="MOB25_02715"
     CDS             10001..10273
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003186189.1"
                     /locus_tag="MOB25_RS02720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_02715"
                     /product="hypothetical protein"
                     /protein_id="WP_268294987.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 9.2e-09,
                     bitscore: 31.2, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIIRNQETATTVLENECIVLNLDNGQYFGLEGALKELWIEIENE
                     RKDKKDILIKWQSAFDQTEEELSAILNEAIRELTHHKLIKIEDKS"
     aSDomain        10013..10258
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_MOB25_RS02720_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="2.50E-10"
                     /identifier="RREFam002.1"
                     /label="MOB25_RS02720"
                     /locus_tag="MOB25_RS02720"
                     /protein_end="86"
                     /protein_start="4"
                     /score="31.2"
                     /tool="antismash"
                     /translation="RNQETATTVLENECIVLNLDNGQYFGLEGALKELWIEIENERKDK
                     KDILIKWQSAFDQTEEELSAILNEAIRELTHHKLIKI"
     gene            10273..10737
                     /locus_tag="MOB25_RS02725"
                     /old_locus_tag="MOB25_02720"
     CDS             10273..10737
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003186187.1"
                     /locus_tag="MOB25_RS02725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_02720"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_268294986.1"
                     /sec_met_domain="PF13471 (E-value: 9.6e-15, bitscore: 50.6,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKRAPVKNHEYFTTVHAFVRMMLLNHDFEEAYEKIAIHLFPLYA
                     SAKPRGAGLLDIDELLRHGEYLYALDEDDHLVTSCVSIALTIQSILFSNGSDADLVIGV
                     KKIDDKLFSHAWVQMENGQSIDPNHKNKNLKVLQMYKMSAYAERWVLSLV"
     gene            10734..12734
                     /locus_tag="MOB25_RS02730"
                     /old_locus_tag="MOB25_02725"
     CDS             10734..12734
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017474082.1"
                     /locus_tag="MOB25_RS02730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_02725"
                     /product="asparagine synthetase B family protein"
                     /protein_id="WP_268294985.1"
                     /sec_met_domain="Asn_synthase (E-value: 1.6e-21, bitscore:
                     73.3, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIWFGMQGDNYVAWQEWVSAVKRWGRAERIHSYSSGIANMAEAH
                     IRYDEAFRPSTQTNLLHPVILDGWISGGLNAKSDGTRKIESDDKLYASLKQDKAAMLSH
                     SHGEFTMMWWDDSLHSLVLATDIYATRPVYYWVNPKGEWFAANDLRILLLVHDIPFAID
                     QDVCRMFPTSGFAVGENGFEDRTFFKGIRKVPAASYAVLGRDHEVHVHSYWGLPQLLNV
                     KDLAGDAVPRFRELFQKVTADRLKDQKHIVELSGGLDSAAVTAAAVAGGCKEQLLAVNI
                     SFAEPDMILSHDKDLVKNMMRDMDIPGLIILGDATAKIPNAEIGRDPLWFVDGPDPRAN
                     SLVNETFTVIAEEYGASSVLTGEGGDFIFSGEVSVLDSLLRKRHFSEIYKLLREWSGGS
                     MKEMLKLGFQYGIAPFMPYIGEKLYYDLLWSDTEYELPEYFTEEHRKREREINKEDHLR
                     YRKSRELSVWGKRFHFDFLWPRARYMDAVGVTLPTYHPFLDRRLIEFSFSVPPEQHFDV
                     LKGLEEHYAGSKMLLRKSFTDILPAYVYNRSTKTTYAHMARKSFMNDRRHVLQLFEPGE
                     RVFVEELGIIKRDIWWKHLLAMAIRSEDPNNDLGMGYQYMRSVIDLEIWLREASKGKEH
                     LLDRSRPGKPRVMADIETVNTPEKAKIYSYQ"
     gene            12777..14717
                     /locus_tag="MOB25_RS02735"
                     /old_locus_tag="MOB25_02730"
     CDS             12777..14717
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009329820.1"
                     /locus_tag="MOB25_RS02735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_02730"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_268338002.1"
                     /transl_table=11
                     /translation="MKHIQEPLQTAGLLGKMVWKSGPWLMICMVFFMLIEAGAPLIQLY
                     ASKEMIDGIVEQEAVIHAEIWAVIYAGSLVMISVVKSLEKWVKAMLSERSMITVNSLLI
                     DAFDRIPGMRFFEDPKYRDRLETLRDRSTWLPSQFINISSNLVTAIMSLAGVVLIIAYL
                     SPVLAVILILSTAPFAFVHNHYNEMEWEYHKDYAPVRRRAAYARHILLGRRSAKEVRLF
                     GLGSFFLDLYQSAFKGLYSVLRNIQVRSARWSVLTGFLSGAGTGLGYFWILSQSHSSSF
                     SVGDISLYLGAVFQLSAALRDIAKEGADTFDIWRMGRDFFLFMNAEKDIRLPSNGESLG
                     DEGPLAVEFKNVTFRYPFREAAAGSRVNEAEADEDEDEEDLDMLDELEDEEEMREHDEQ
                     PQSDDMHSGDVLNRISFSVSPGERIAIVGANGSGKTTLIKLLCRFYEYDEGEIKVNGKD
                     IRQVDLHELRNRMAVVFQEFGKYELSLRHNIAIGRTEALGDEEKLSAAARSAKLEPIIE
                     GLPEGLETMIGPEWGGTDFSGGQWQRIALARSFMKDAGLVILDEPAASLDIRAEYDIFR
                     QFHSFTEGKTVIMISHRFSTVKMADRILVLKNGRIAEEGSHQELMDKNGEYSRMFRMQA
                     KSFQGRDEVYC"
     gene            14711..16519
                     /locus_tag="MOB25_RS02740"
                     /old_locus_tag="MOB25_02735"
     CDS             14711..16519
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003186181.1"
                     /locus_tag="MOB25_RS02740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_02735"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_268338003.1"
                     /transl_table=11
                     /translation="MLKFYSLFKKLPQTASIIFYGLTLFWRCDPLKSAVLFLITLLGAM
                     LGPLLVWLSAEVIDEIARAPFELSSWNTLVWASFAYIAFTLIVDALQPVAEMQKRLLTA
                     KLEAYLDEMLMKKAISIPDIAAFEDASFHTNTQIIRYNEYFVTMWVSIVSQTFGGMVMI
                     AASSLLIGMSAPWVPLLFLILAVPKLYWEAKLNNATFEGRKEVQELRRRAEYYAGVPLM
                     SETAGEVKIYNLVPFFKSFYKNTSMELLHTLSNDQKKLALYQLFWSVLQSLAAGAVLIY
                     IVHQAFHGGLSIGDVMLFIGAAVQFNEGINEMFAAFAIGARETRHLGNVHSFLNSKNSM
                     ENGEIAPAVQKQKGFTCDQVEFSYDGTKTVLDIHKLDIPLNKTTVLVGENGSGKSTLVK
                     LLLRYFDPNQGTISYNGLPLYKYDIEDYRSNAAAVFQDFLRYEMTLKYNIGLGDISSCT
                     DLAKIKSASAFGGVDQFLHKLEDDYETELGRLFGGRNLSGGEWQRVAISRAFMRDESAD
                     ILIFDEPSSALDVFIEEEIFDKLQKLTQGKTVIIVSHRLSTARFADHIVFLEKGRVAEA
                     GTHQELMKNQAQYAELYRLQAEKYAQ"
     gene            16531..16986
                     /locus_tag="MOB25_RS02745"
                     /old_locus_tag="MOB25_02740"
     CDS             16531..16986
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003186178.1"
                     /locus_tag="MOB25_RS02745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_02740"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_268294982.1"
                     /transl_table=11
                     /translation="MSNIEELRLFRKEDIEWLQTWFEDAEVKRRLEGMMPLDEWFNFAG
                     GNENYRVWAALKEGKPVGVVMVEVEQDSTGNIALLVDPFLRGGGYGKALIKRTMALPEL
                     SRINKWFAGIEEDNKRCLACFRSVGYSLEHDQPDEDGYYSLIYFPES"
     gene            17004..18203
                     /locus_tag="MOB25_RS02750"
                     /old_locus_tag="MOB25_02745"
     CDS             17004..18203
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011198409.1"
                     /locus_tag="MOB25_RS02750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_02745"
                     /product="clostripain-related cysteine peptidase"
                     /protein_id="WP_268338005.1"
                     /transl_table=11
                     /translation="MNLIKWIVFSVISVAFFQPASAALLKEKDDYTILVYMIGSDMESD
                     FHMASDDIQEMMDAGSSSNVNVVLQTGGAKKWANPSISHKVNQRWKVEHQKLVSLENIG
                     KKNMDSPSSVTDFITWGVKKYPAKKYVLIFWGHGLGSVDGYGGDENFGNKKMKISELQS
                     GIKKAYEHTKQKFDLIGFDNCKMAGIETAYALKDYGRYMLASVDYTNQNGWDYKRALQS
                     VQDDPSIDPKELGREIAAGYIQQSKENGETEDLQQSFIQLNRVKDAVDALDRLSLSMNR
                     ALKEPDGKRLLHYARLAAEDYADESDMVDLADLSSLIGQQIGAEKEAKEVVKSVKKAVI
                     MNIKSPEHPRGSGMSVYYPARDNQKWFAEKSNIYHLLDFSARYQTFIKDYSHSTFNFDL
                     "
     gene            complement(18251..18511)
                     /gene="ywcE"
                     /locus_tag="MOB25_RS02755"
                     /old_locus_tag="MOB25_02750"
     CDS             complement(18251..18511)
                     /codon_start=1
                     /gene="ywcE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003186174.1"
                     /locus_tag="MOB25_RS02755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_02750"
                     /product="spore morphogenesis/germination protein YwcE"
                     /protein_id="WP_043925241.1"
                     /transl_table=11
                     /translation="MDMFFAYLLIASATPLFLWLDNKKVAISSIPPIILMWVFFFFYMT
                     SSLSPTGHSLMIVLFILNVVIAHVAAFMIYGLPLIRKHMSR"
     misc_feature    complement(18534..18548)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 20.52"
                     /tool="antismash"
     misc_feature    complement(18649..18663)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.12"
                     /tool="antismash"
     misc_feature    complement(18651..18662)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.15"
                     /tool="antismash"
     gene            complement(18937..20292)
                     /locus_tag="MOB25_RS02760"
                     /old_locus_tag="MOB25_02755"
     CDS             complement(18937..20292)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017474081.1"
                     /locus_tag="MOB25_RS02760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_02755"
                     /product="YjiH family protein"
                     /protein_id="WP_268294980.1"
                     /transl_table=11
                     /translation="MDKALQKRKRLDLIKFLVPSLIGIILFMIPVKIEGNLTIPIAVFS
                     NALQKLLQQQLPLIMTVIVTATFILTFITKTFHPAFIKKSEFFYNLLNVSLFWYIVRLF
                     GMIFAVMAYFKIGPEAVYAKSTGGTLLFSLLPVLFSVFLFAGLFLPFLLNFGLLELCGA
                     LMKKLMRPVFKLPGRSSIDCMASWLGDGTIGVLLTSKQYEEGFYTKREAAVIGTTFSVV
                     SITFCLVIISQVGLAHMFVPFYLTILLAGAAAAVISPRIPPLSRKADTYITDQADHDQE
                     EIPDGYTPFQWGLSRAVAKAKQNTSVKDFLRDGTKNVLDMWMGVAPVVMALGTAALIVA
                     EYTPVFKWLGLPFIPLLELLQVPEAAEASQTLVVGFADMFLPSVLGSGIESEMTRFIIA
                     CVSVTQLIYMSEVGGLLLGSKIPVTFLDLVLIFLVRTLITLPVIVLCAHFIF"
     gene            20571..21755
                     /locus_tag="MOB25_RS02765"
                     /old_locus_tag="MOB25_02760"
     CDS             20571..21755
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003186169.1"
                     /locus_tag="MOB25_RS02765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB25_02760"
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="WP_152846156.1"
                     /transl_table=11
                     /translation="MSQKKNITNPFYQGDLIFVYIVFFIISVVAVYAAQQFNQYNEPFA
                     MKQSLYYLLGAFIIIVFLYFDLEQLEKLSFYFYLLGILMLIVLKFSPAYIGSYRFAPVI
                     NGAKSWFMLPGFTLQPSEFMKIGLIMYLASFMSKNGPVGKRTLKEDWIFLLKIAGIIIV
                     PFGLILEQDTGTAGIVAFVILVMVFLSGVNWKLISLIFGTGLAAVVLILFVIIKFPDVA
                     GALGVEPYQINRVMTWVNPSEQNADDKMQVERAQLAIGSGKVFGNGVSDLQVYVPEAQT
                     DFIFAVIGESFGFVGCTFVVIMFFFLIYRLVVLIDRIHPFSRFASFFCAGFTALIVIHT
                     FQNIGMNIGIMPVTGVPLLLVSYGGSSVVATLIGFAVVYNSSCQLTKYQSYMFK"
     misc_feature    complement(21793..21807)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 21.34"
                     /tool="antismash"
ORIGIN
        1 ttatacttat tgccggggtt caaaaaatcc gccccgagcg gagtagctgt tttcatttgt
       61 tcaaacatgt tcgtcaggct gaagccgaat tttgaaaaaa cgatgactga aatgatgagc
      121 gtccccgcca tcaagagaac ggccttgatg atctggaccc agctggttgc aatcattccc
      181 ccgaatacga cgtagatggt catcaaaacc ccgacaatgc acactgccag cgtataatcg
      241 atgccgagca gaagcttgat cagcgcgccg gcgccgacta attgtgcaat catataaaag
      301 gtggagatcg tgatcgtgtt taatgcggcg acaccgcgaa ttttcttttg tttaaaacga
      361 gaggcaatca tgtccgccat tgtaaatttg ccgaggtttc tgagcggttc tgctacaata
      421 tatagcacga ctaaataagc gacgaggaag ccgatgctgt agaaaaaacc gtcaaaccca
      481 ttcaaagcga tcatcccggc aattccgagg aaagaagccg ctgacatgta atctcccgcg
      541 atagccagtc cgttttgaat gccggtaagt cctcctcccg ccgtgtaaaa ctcattggcc
      601 gtttttgtct gtttggctgc gaaatacgta atgacaagcg tgagggcgac aatgacaaga
      661 aacagaataa aggctgtggc actcatgaat caacgcctcc aatcttcttt ttaaaatcgc
      721 ttgcaatttg atcgaattga ccggcttttc tcgtatacac aatgcacagc gtccacgtca
      781 taacaaactg agcaatcgcg aaaacccatg cccatgtgat ggctccgact gccggctgat
      841 tcaaaaatgt gaagtatgat gtcataaccg gcagcaggaa ataaaagagc aaaaagaaaa
      901 tcgtcatcgg tacaataaaa gcccgtttcc gctttaacaa cagctggaac tccggagatg
      961 ccgcagcttt gctgtaatct attttgcctt ctctcatttg ttctttgccc ctccttgtat
     1021 ttgtctgaaa agatacaaca aaggtatgta acaagctccg gatttattct tcaattttca
     1081 caaagtctct tatttatata agatgaaaga cctgaccatc tcgaataaat gttttttcca
     1141 taaatcaaac cgtttgttca ccttttcatt tgtcatgctt tccgccccgc ttccgactct
     1201 gtcagcttcc ttctcagttc atttgcagcc acaatcgctg cccggtctgt catcacgccg
     1261 ccgggcttgt tccctttggc gagcagatag ccgtcgaatg tcatgttcat aaaatcaaag
     1321 atgtattgaa actgttgaat gagcggcagc ccttttaagc ggggatcatc gtccccgaca
     1381 gccgcgacgt agactgtttt tttcgccatt tcctgtttaa atgcagatct cccgtgctcc
     1441 atcaacgtct gtgaccagcg gtcaataaag tttttcatca aacccgacat tccgtaccaa
     1501 tagatcggag tggcaaaaat caggatatct ttctccagca cccggctgat caggtttctg
     1561 tagtcatcat caggataaaa aggagctgta ttgctgtgcc tgtagtctga tacgggctca
     1621 atgtgatagt ttcgcaggta tatcttatcg gtatcaagcc cgtctactaa tcgattcacc
     1681 agttcttccg tatttccgtt ttcgcgggag cttccgcaga ttgctgctat ccccatattc
     1741 atcatcctcc ttggaatcgg tcatgaattc agtttaagat aacaacaacc atcagtaaaa
     1801 ttgatatttt agatatttac catcgaaaaa aacgatgata caggcaaatg cttaattgaa
     1861 aagagagtgt ggaaaggaag cctgaggatg ttatcagaag gatcaaggcc aaaagctccg
     1921 ccccctatca ggagaaaggc aatcgaaacc gatgcagaag aaagtgtatg gggatgctga
     1981 catcagcgtt ggtcagcaat gcctctaaaa cgccttaatc aatccggtct ggtacccctt
     2041 aagagagtga agctggaaaa atgaaacgac ctatgtacag ggcaaaaggt aaggctgctc
     2101 cttaataaaa tgcgcgttta tatggagcag tcagaatgta tacacaggca gcaagcctgc
     2161 tgctcaaata cgtcattatc aattaaaaca ctcgttaaaa cagccggttg gatcatcttg
     2221 atagaccaag attcaacaga accgcctgtt tttttggata actgatgctt ctaaacgctt
     2281 attgctttat ctgtttttca gcatcgcttt ggatgggctg actgcgaaga aattctttca
     2341 catcttcaat ttgcagccca agttttttcg cctccttcat caaaatcacc caatctttgt
     2401 ccaacttgtg tttcgtttga gtattcatag cttcctccaa tatgataaga cgttgttcac
     2461 ctcaaagaaa aaacggcttt tccttgagat gcaataaaag ttataaaaca acagccatgt
     2521 gaaaacaatg acaaatttca taaaaaattc acaaagtcat cattgataaa cctacctatt
     2581 ccctaaataa ctgactaaaa aaaccaaaaa atcttagatt cttacttata ataataaaca
     2641 atcaattact gactggatag tattcaaata aaaatgatca tttttcccta ttaagaattt
     2701 ctcaattgca gccgaatatc ctttgaatat tctaaaaata aagaagggtt ttttgagaga
     2761 ttattgtgta gaaatattgg aaaatcaatg gtttcaaggg attatttaga ttgcagatat
     2821 tgtggatagg gagggtcctt tgggcttagt tgctgtatgg gttaaagagg ggtaatacga
     2881 aaatactatt atcgaccagc attaagtgga aaaaaagaac attggtttca aatgcagtga
     2941 aaaaagtata gcttttgcct caaaatcgcg ttaggttcac caaggaaaaa ccattgtcat
     3001 ggataaaacc cgaactattc cttgtaaggt atttaatgga ataggagtcc ctcaatttgt
     3061 tttaccccaa gtttttattt gaagaaatga tgaaaataca agctggaaaa tgctgaaggt
     3121 ggtaaaatga aaaagcagat atatcatcac cttgggattg aaaaagagag tcacaggcgt
     3181 ttgatagatt caaaatagaa ggataacgcc gctgaaagga gagaaatgaa ttggcaatat
     3241 tagtatgcgg aggggctggc tatattggaa gccatgctgt agcggaactg ttaagccgca
     3301 atgaagaagt cgtgattatt gataacctgc aaactggaca tgaagaggcg gctttaaagg
     3361 gagcttcttt ttataatgga gatctgcgca atgaagcatt cctgagaaaa gtgtttcagg
     3421 aaaacgacat tgaggctgtc atgcatttcg cggccgattc attggttgga gaaagcgtaa
     3481 cagatcctct caaatattat gataacaatg tttacggagc cgtttgcctg ttaaaggtca
     3541 tgaaagagtt tgatgtgaag caaattgttt tctcatcaac cgctgcaaca tacggagaac
     3601 cggatcgggt gccgattatg gaaacagatc cgacggatcc gacaaaccca tacggggaaa
     3661 cgaagcttgc cattgaaaaa atgctgaagt ggtctgaaaa agcatacgga atccgtcatg
     3721 tcgtccttcg ctactttaat gttgccgggg cgcatgtaga cggtttgatc ggcgaggatc
     3781 atcagcctga aacgcacctg atcccgatca ttcttcaagt cgcgcttggc aaacgggaca
     3841 agattatgat tttcggcgac gactatccga ctccagatgg cacgtgcatc agagactaca
     3901 tccatgtgat ggacctggtt gacgcccata tcctcgctgt cgaaaggctt cgaaacggcg
     3961 gagaaagcgc cgtatacaat ctcggaaacg gcacgggctt ctcagtcaaa gaagtcgttg
     4021 aaacagcccg gaaagtgaca ggctgtccga taccggcgga ggttgcagag cggcgcgcag
     4081 gagatcctgc acagctgatc gcctcttctg aaaaagccgt gaaagaactt ggatggcagc
     4141 cgaaatacgc caaactggaa acgatcattg acagcgcgtg gaagtggttt aaagcacatc
     4201 cgaacggcta tcaaagctag aatgcgataa caactgttaa ataggatgaa aaagagcttt
     4261 cagttacaga aggaagctct tttttgatgt tctgaagttt aaagcgggtt gtcagcaggg
     4321 aaaaggaatg gaggaagata atgattcacc ttgaaaaaat ttaacaatgt taaattaatg
     4381 attgaccaaa gttttttatt gtggtaaacc taaatttgac agattttttg ttccggaggg
     4441 atttgtcagc gcttgctatg tgtgtaaaaa gaactaagaa attaccagtc tatttccttc
     4501 attattcata atatcatgaa caaaatttga cgattttgtg acatttgggt gaaaaaaagg
     4561 tgaacaatcg aaaaaaataa ggctaattgg tgaagatttt gatagcatag caaggtagaa
     4621 gaaaaaagtt tttcagaatc cttttatctt agatattctg accaaatttt agacatcatt
     4681 aaggaaggat ggtgatcctc ttgttcagag catttaaacc actgattatg ctgactttgc
     4741 tttcctccgt ttttttattg ggcggctgca gtcaaatcgc ggtattggat cctaaaggac
     4801 cggttgcttc gcagcaaaga gatcttattc tattatcgat tggatttatg ctgtttatcg
     4861 tagcggtcgt atttgtcctt tttactgtga tgattgtaaa ataccgtgag cgtaaagaca
     4921 gaaagtctcc ttacagcccg gaagtagaag gcaatacatt tttagaaatc gtctggacag
     4981 tggttccgat tttaattgtt attgcgctgt cagtgccgac agttcaaaca atttattctc
     5041 tagaagaggc tccaaaagca tcaaaggaca aggaaccttt ggtcgtatat gctacatctg
     5101 tcgattggaa atgggtattc agctatccgg aacaggatat cgaaacggtc aactatttga
     5161 atatcccgac agacagaccg atcttgttta aaatctcatc tgccgactct atggcatcac
     5221 tatggatccc gcagcttggc gggcaaaaat atgccatgtc cggaatggaa atggagcaat
     5281 atttacaggc agaccatgag ggtacttata aaggccgaaa tgcaaacttc acaggtgaag
     5341 gttttgcaga acaacagttt aatgtcaatg cggtatctga aagcaaattt aatgactggg
     5401 tgaagaaaac gcagaaagaa gctcctaagc tgacgaaaaa ccagtacgat gaattgatgc
     5461 ttcctcagca tgcggacgaa atgacgttct catcaacaca cctgaagtac gttaatcacg
     5521 gaaatgatgc ggaatacgcc attaaagcgc gcgaaagatt gggctataaa ccagtgtctc
     5581 cgcactcaaa atcagatccg tttgaagacg tgaaaacaaa caaagatcaa aaacaatctg
     5641 aagaccaaga ttctcactag gaaaggagga agcttgcatg aatttgaaat gggacgaatt
     5701 cataattaca ggtgacccat taattcttgg agcacagatt tccattttgc ttacatccat
     5761 tgcaatcgta tttgtgctga catacttcaa aaaatggaaa tggctttgga gagagtggat
     5821 taccaccgtc gatcataaac gtttaggaat catgtacctt attgccgcag tgattatgtt
     5881 tttccgcggc ggtgtcgacg ggttaatgat gcgtgcccag ctcacgcttc ctaataacgg
     5941 ctttttagat tccaaccact ataatgaagt atttacgaca cacggtacga tcatgatcat
     6001 tttcatggcg atgccgtttc ttattggatt aatgaacgtg gtcgtgccgc ttcaaatcgg
     6061 tgcgcgggac gttgcatatc cttacttgaa caacttgagc ttctggacct tcatggtcgg
     6121 agcgatgctg tttaatattt cattcgtcat cggcggatcg ccgaatgcag gatggacggc
     6181 ttacatgccg cttgcaggca atgagctgag tcccggacct gggcagaact attacttgct
     6241 cggacttcag atcgcgggta tcggtacgct tctcaccggg atcaacttta tggttaccat
     6301 cctgaaaatg cgtacaaaag gcatgaccct atggcggatg ccgatgttca cttggacaac
     6361 gctgatcact tgtgtgatta tcattttcgc cttccctgtc ttgacagtgg ctttggcgct
     6421 gatgacattt gaccgcttgt tcggaacagc ctttttcacc ttggcgaacg gcggtatgcc
     6481 gatgctgtgg gcgaacctgt tctggatttg gggacatcct gaggtttaca tcgttatttt
     6541 gcctgctttc ggtatttttt cagaaatcat tgcaacattt gctagaaagc agctgttcgg
     6601 ctataaagcg atggtttatt ccattgttgc gatttcggtt ctcagctttg tcgtttggct
     6661 gcatcacttt ttcacaatgg gcaacagcgc ggcggtcaac tcgttcttct cgattacgac
     6721 gatggcgata tcggtgccga ccggggttaa aatctttaac tggctgttga cgctgcatcg
     6781 aggcagaatc aaaatcacaa cgccgatgct gtggtcgctt gcatttattc cgaacttcgt
     6841 catcggcggt gttacgggcg ttatgcttgc gatggcagct gcggattatc aatatcacaa
     6901 cacatacttc ctcgtatcgc acttccacta cgtgctgatc gcgggtactg tgtttgcatg
     6961 tttcgccgga tttatcttct ggtatccgaa aatgttcggt cacaaactga acgaacgcat
     7021 cggaaaatgg ttcttctggc tgttcatgac aggctttaac atctgtttct tcccgatgta
     7081 tttccttgga ttgcagggaa tgcctcgccg tatttacaca tacggagcag aagacggctg
     7141 gactgcattg aacatgattg cgacattcgg cgcattgctg atggccgcag gattcatcgt
     7201 tctctgctac aacattttct acagcttccg tcattcaaaa cgcgaggaat caggagatgc
     7261 ttggggaatg ggtcgtacgc ttgaatgggc tacatcttct gcgatcccgc cgcactataa
     7321 ctttgcggtt ctgcctgagg tcacatcacc tgacgcattt gcgcaaatga aggaagacaa
     7381 tgtcgagatt catcctgaaa gcaagtttaa aaagattcat atgccgagca attcaggccg
     7441 tccgtttatc atgtcattat gcttcggatt tgctggattc gggcttgtct ttgaatggtt
     7501 ctggatggga atcgtaggtc tgatcggtgt attcctttgt atgattcttc gttcatttga
     7561 atatgacgac ggctactatg taagtgttga ggaaataaaa gagactgaac gaaagaatgc
     7621 caagtaaagg aggcgggatt gatggaacat gcagaacaca gcaattctaa cgctcctatg
     7681 gaataccgtt ctgaaacagg aaggttgaat atccttggct tttggatttt tcttggagcg
     7741 gagattgctt tattctctac gttatttgcg acctatgctg ttcttcataa cagaacagcg
     7801 ggaggcgtac tgccggcaga actgttcgac gcaaagctcg ttttaatcat gacgttcctg
     7861 ctgttaacga gcagtttcac atgcggcatt gcagtgcatg agatgcgccg cggcagtttg
     7921 aaaggcgtga tgatctggat gatcattacc ctgttgctcg gtgctggttt tgtcagctat
     7981 gagctttatg agtttaatca ttatgtacac gaaggtgcca ctttatcgac aagtgcttac
     8041 tggtcatctt tctttgttct attgggaacg cacggactgc acgtatcgat cggtatcttc
     8101 tggattatcg gcattttgct tcagacgaaa aagcgcggcc taaccccgca aacgtctgct
     8161 aagctgttta tctcaagttt gtattggcac ttcttagacg tggtatggat cttcatcttt
     8221 accggtgtct atttgatagg gttggtgaat gtataatggc agcaaaacaa tcggctgaac
     8281 acagccactt tccttggaag catattgtcg ggttcgtgtt gtccattgtg ctgaccttat
     8341 tggccttgtg ggtgatctat acggatttaa gcatggctgc aaagctgtgg attattttcg
     8401 gttttgcgat cgtccaagct ggacttcagc tcttaatgtt tatgcatatg actgaaagtg
     8461 acagcggcaa aatccaagtc gggaatacgt tgtttgccgc atttattgcg gttgcgatta
     8521 ttgccggttc tgtctggatt ttcgctgctc acaactatca cggagacaac cctgagggcg
     8581 gttctccagg tgcaaaacat tctgagcaca gcggacatta attgattggt aaaagagtgc
     8641 ggatttcaac ggtccgcact cttttttgat tgctgaacgg aaaaagagag agccgcaggc
     8701 tctctctttc tcatacactc ttaaccgcgt tttacgccgc ggccgaattt gccgtcgccc
     8761 ggcttgctct ttttagaaag agtaacagtc aggaatgtac catagttttt aacttgagca
     8821 ctttccaatt tgcgcatctg tgtcacctcc ttattacttc cagttgatta catattcatg
     8881 ctatcataga ataaagtggt aaaaaccaca aaaaggcact aaaacccgcc atcatccttc
     8941 aattctattc atggggtttt tattgcggta tttgttcgga ggaaactgac ttaaggagag
     9001 tgttactgat gattcgcgtg ttgttagtag acgactacag ggttctgaca tccggaatga
     9061 aggaaatatt aaaaaaatat aatatggatg tcatcgtttg ccacgaagga aatgaagctc
     9121 tcgacctctt aaaaaatcaa gaggtacata tagacgtttt tctttatgat ttaaaaatgc
     9181 cggggatgaa cgggttggaa ctgtctctta aaacgctgga aatcgcacct caatccaaaa
     9241 ttatcattat gttttcggga gatgaaattc actcatattt taataagctg atcgaagccg
     9301 gagtcaaagg gtttatcgat aaatcgtata cagacagcat gattgcttcg agtattttat
     9361 tgtgtttaaa aggggcggtg ttatttcccg acggcttgct gcaaaaactg aggctcgact
     9421 ccgatctcgc ggtggacgag catttaacag acacagaact ggatattttg cagaaggtgg
     9481 ccagcggtaa aacaaataaa gagatcgcag cagacttaca aatgtcgacg cgcaacgtag
     9541 agtatcactt gagcaaaatt tataaaaagc taaaagtaac gtcgcggtac tgtgcagtaa
     9601 aaaaaggaac gatgcttaat ttgatcaagc agaaagctta aacaaggtat atattcgttt
     9661 ttccctgcaa aagagagtcg ataggctctc tttttctttt tcctccgaat aaatcccgta
     9721 ataatggccc attgatgcag ttggctaatc atgtcggttt tcggtagttt tttgcggttt
     9781 ttttgatatt gtcctgtgat aatctgattc atgtgatcag ttggtaaatt caggagtatc
     9841 gttgcattgc aggctctttt taaaacgctc cagcgctgat atgataacgg catttgcctg
     9901 gggagtggaa agaacatcat gtataaagtg ctgaaagaga gcttaccggc tctcttctcc
     9961 tttatttttc tgaaatcatg catacagggg aggtctaact ttgaaaatta ttcgaaatca
    10021 agagacagcg acaaccgtgt tggagaatga atgcatcgtc ctaaacctgg acaatgggca
    10081 gtatttcgga ttggaagggg ctttaaaaga gctgtggatc gaaattgaaa atgaacgaaa
    10141 ggataaaaaa gatattctga tcaagtggca atcggcgttc gatcagacgg aggaagaact
    10201 gtcagcgata ttaaatgagg cgatacggga actgacacat cacaagctga ttaaaataga
    10261 ggataaaagc tgatgaaaaa aagagcgcca gtcaaaaatc atgagtattt tacaaccgtt
    10321 catgcttttg tacgtatgat gctgttaaat catgactttg aagaagctta tgaaaaaatt
    10381 gcgatccatc tgtttccgct gtatgcgagc gcaaagccaa gaggcgcagg gcttcttgat
    10441 atagacgaac tgcttcggca cggcgaatat ttgtatgcgc ttgatgaaga cgaccatttg
    10501 gtcacttcat gcgtttctat tgcattgacg attcaatcta tattattcag caatggatct
    10561 gatgctgatc tcgtgatcgg ggtcaagaaa attgatgaca agctgttttc tcatgcgtgg
    10621 gttcagatgg aaaacggcca atcgatcgat ccgaatcata aaaataagaa tttaaaagtt
    10681 ttacagatgt ataagatgag cgcttatgct gaaaggtggg tgttatctct agtatgaaaa
    10741 tatggtttgg aatgcaggga gacaactacg ttgcatggca agagtgggtt tccgccgtca
    10801 agagatgggg gcgggcggaa cggattcaca gctacagcag cgggatcgca aacatggctg
    10861 aagcgcatat ccgatacgat gaagctttta gaccttcgac ccaaacaaac cttttgcacc
    10921 ccgtcatctt agacggctgg atcagcggcg gtcttaacgc aaaatcggat ggcacccgaa
    10981 agatcgaatc tgatgacaag ctgtacgcgt cgttgaagca ggacaaagct gccatgcttt
    11041 ctcactcgca tggcgagttt acaatgatgt ggtgggatga cagtctgcat agccttgttt
    11101 tggcgactga tatatacgca acccgtccgg tttactactg ggtcaatccg aaaggagaat
    11161 ggtttgcagc gaatgacttg cgcatccttt tgcttgttca tgacattcct tttgctatcg
    11221 atcaagatgt gtgcagaatg tttcctactt caggcttcgc tgtaggagaa aacggctttg
    11281 aagatcggac gttttttaaa ggaatacgca aagtgcctgc ggcgtcctac gctgttctcg
    11341 gccgggatca tgaggttcac gtgcacagct attggggact tccgcagctg ttaaacgtga
    11401 aagatcttgc cggagacgct gttccgcggt tccgggagct ttttcagaaa gtgacagcag
    11461 atcgtttaaa agatcaaaag catattgtcg aattaagcgg cggactggat tcagctgctg
    11521 taaccgccgc agcagtggca ggcggatgca aggaacagct gctggccgtc aacatatcat
    11581 ttgccgaacc tgacatgata ttaagccatg ataaggacct tgtaaaaaat atgatgcgag
    11641 atatggacat ccccggcctg atcattctag gagacgctac agccaaaatt ccaaacgcgg
    11701 aaatcgggcg tgatccgctt tggtttgtag acggtcctga tccgagagcc aattcactgg
    11761 tcaatgagac ttttacagtg atcgctgagg agtatggtgc ttcgtctgtc cttacaggtg
    11821 agggcgggga tttcattttt agcggagaag tgtcagtact cgattctctg cttcggaaga
    11881 gacatttttc tgaaatctac aaattgcttc gtgaatggtc aggcggcagc atgaaagaga
    11941 tgctgaagct cggatttcaa tacggaatcg cccctttcat gccttatatc ggcgaaaagc
    12001 tctattatga cttgctgtgg tcagatacgg aatatgagct gcctgaatat tttactgaag
    12061 aacaccgaaa gagagaacgg gagatcaata aggaagatca tcttcgctat cgaaaaagcc
    12121 gggagctctc agtgtggggc aagaggtttc attttgactt tttgtggccg agagcgaggt
    12181 acatggatgc cgttggtgtg acattgccta cgtaccatcc gtttttggat cggcggctga
    12241 tcgaattttc attttctgta ccgcctgaac agcattttga tgttttaaaa gggcttgaag
    12301 aacattatgc aggctctaaa atgcttcttc gcaaatcttt caccgatatc ctgcctgcct
    12361 atgtatataa cagatcaacg aaaacaacat atgcccatat ggccaggaaa agctttatga
    12421 atgaccgcag acacgtcctt cagctatttg aaccggggga gcgcgtcttc gttgaagaac
    12481 tcggcatcat taagcgcgat atatggtgga aacacttgct ggctatggct atccgttctg
    12541 aagatccaaa taatgatctg ggcatgggct atcagtatat gagatctgtc attgacttgg
    12601 aaatatggct cagggaagca tccaagggga aggagcacct tctcgatcgg agccgtccgg
    12661 gaaaaccaag ggtcatggct gatatcgaaa ccgtcaatac gccggagaaa gccaaaatat
    12721 actcgtatca atgaccacaa taggtataga aaatgaaggt gaagcatgtg tggaagatga
    12781 agcatatcca agagccgctg caaacggcgg gcctgcttgg gaaaatggtc tggaaatccg
    12841 gcccgtggct gatgatttgc atggttttct tcatgctgat cgaagccgga gcacctttaa
    12901 tccaattgta cgcttcaaag gaaatgatcg acggcattgt cgagcaggaa gccgtcatcc
    12961 atgcggaaat atgggctgtc atttatgcag gaagcttggt catgatcagt gtcgttaaat
    13021 cattggaaaa atgggtaaag gcaatgcttt ctgagaggtc gatgatcaca gtcaacagtt
    13081 tgttaatcga cgcttttgac cgcattccgg ggatgcgctt ttttgaggat ccaaagtaca
    13141 gggaccggct ggaaacactg cgggatcgtt cgacatggct accttcccaa ttcattaata
    13201 tcagttcgaa cttggtgacc gccattatgt ctttggcggg cgtggttttg atcatcgcct
    13261 atctgtcgcc cgtccttgct gtcatcctta ttttgtctac cgctccattc gcttttgtcc
    13321 ataatcatta taatgaaatg gagtgggaat atcacaagga ttacgcccct gtcagaagga
    13381 gggctgcata tgcgcgccac attctgctcg ggagacgatc tgcaaaagaa gtacgcctgt
    13441 ttggcctggg atctttcttt cttgatttat atcaatctgc ttttaaaggc ttgtattctg
    13501 tgttgcggaa tattcaagtc agaagcgcgc gctggtcggt tttaacgggt ttcttatcgg
    13561 gggccggaac gggtttgggg tacttttgga ttctgtctca atcccattca agcagtttct
    13621 ctgtggggga tatatcgctg tacttagggg ccgtgtttca attatcagcg gctctccggg
    13681 atatcgccaa agaaggtgca gatacgttcg atatatggag aatgggaaga gacttttttc
    13741 tttttatgaa cgccgaaaag gatatcaggc ttccttccaa tggcgaatct ctcggggacg
    13801 aaggaccgct ggcagtcgaa ttcaaaaatg taaccttccg ctatcctttc agagaagcgg
    13861 ctgccggctc ccgggtaaat gaagctgaag ctgacgagga tgaggatgag gaagatttgg
    13921 atatgctcga tgagcttgag gatgaagaag agatgcggga acacgacgag cagcctcaat
    13981 cagatgacat gcactcaggc gatgttctaa atcgaatcag cttttcagta tcaccgggag
    14041 aaagaattgc cattgtaggg gcgaatggat cggggaaaac aacgctcatc aaactgctct
    14101 gccgttttta tgaatatgat gagggtgaaa ttaaagtgaa cggcaaagac atccggcaag
    14161 tcgatcttca tgagctgaga aacaggatgg cggttgtgtt tcaggagttt ggcaagtacg
    14221 aattgtcact ccggcacaat atcgcgatag gccgcacgga agctttaggt gatgaggaaa
    14281 aacttagtgc cgccgcccgg tctgccaagc tggaaccgat catcgaaggt ttgcctgaag
    14341 ggctggaaac gatgatcggc cctgaatggg gcggtaccga tttttcggga ggccaatggc
    14401 aaaggatcgc tttagccaga tcgtttatga aagatgccgg actcgtcata ttggacgagc
    14461 cggccgcatc tttggatatt cgggctgagt atgatatttt ccggcagttt cacagcttca
    14521 cagagggaaa aacggtgatc atgatttccc atcggttcag tacggtaaaa atggctgacc
    14581 gcatactggt tttgaaaaac ggaagaatcg cggaagaggg aagccatcag gaacttatgg
    14641 acaaaaacgg ggaatacagc agaatgttcc gcatgcaggc caaatcgttt caggggaggg
    14701 atgaggtata ttgctgaagt tttattcgtt gttcaaaaag ctgcctcaaa ccgcttctat
    14761 catattttac ggtttaacgt tgttttggcg ctgcgatcct ttaaaatcgg cggttctgtt
    14821 tttgatcacc ttgcttggcg ctatgctcgg accgctccta gtctggctga gcgcagaggt
    14881 gatcgatgag attgcacggg cgccctttga gctgtcttct tggaatacac tggtatgggc
    14941 gtcctttgca tacattgctt ttacgctgat cgtggatgcc cttcagcctg tggctgaaat
    15001 gcagaaaagg ctccttaccg ccaagctcga agcttatctt gatgaaatgc tcatgaaaaa
    15061 ggcaatttcc attcctgata tcgcggcttt tgaagacgca tcttttcata ccaatacaca
    15121 aatcatccgc tataatgaat attttgtcac gatgtgggta tccatcgtgt ctcaaacctt
    15181 cggcggaatg gtgatgattg cagccagcag tttattgatt ggcatgtctg caccgtgggt
    15241 gccgctgttg tttctcatat tggccgttcc caaactgtac tgggaggcga agttaaacaa
    15301 tgcgaccttt gaaggacgga aagaggttca ggaactgagg cggcgcgcgg aatattatgc
    15361 aggtgtccct ctcatgtctg aaacagccgg cgaggtcaag atttacaatc ttgttccttt
    15421 ttttaaatcg ttttataaaa acacctcgat ggagctcctt catacgctgt ccaacgatca
    15481 aaaaaaactg gcgctgtatc agcttttctg gtcggtatta caatctttgg ccgcaggtgc
    15541 cgtcctgatt tacatcgtac accaggcttt tcatgggggg ttatccatcg gggatgtgat
    15601 gctgtttatc ggagccgcgg ttcagttcaa tgaaggaatc aatgaaatgt tcgctgcgtt
    15661 tgcaatcgga gcaagagaaa cgaggcacct cggaaatgtg cattcttttt taaacagcaa
    15721 aaattccatg gaaaatgggg aaatcgcgcc agctgttcaa aagcaaaaag gatttacatg
    15781 tgatcaagtg gaattttctt atgatggaac caaaacggtt cttgatattc ataagctcga
    15841 tattccattg aataagacga ccgttctcgt gggagaaaac ggatcaggca aaagcacact
    15901 cgttaaattg ctcctgcgtt attttgatcc taatcaaggc acgatctctt ataatggttt
    15961 accgctttat aagtatgata ttgaagatta ccggtcaaat gccgcggctg tgtttcagga
    16021 ttttttgcgg tacgaaatga cattgaaata caatatcggc ctgggcgaca tttcgtcttg
    16081 caccgacttg gctaaaataa aaagtgcttc ggccttcggc ggagtggatc agtttttgca
    16141 taagcttgaa gacgattatg aaacagagct tggcagactg tttggcggca ggaatttgtc
    16201 ggggggagaa tggcagcggg tcgccatatc ccgcgcattt atgcgtgatg agtctgccga
    16261 tattttgata tttgatgaac cctcctctgc gctggatgta tttattgagg aagagatatt
    16321 tgataagctg caaaagctga cgcaaggcaa aacagtcatt attgtctcgc accggttaag
    16381 cacggcccgt tttgccgacc acatcgtatt tttagaaaaa ggaagggtgg cggaggccgg
    16441 aacccatcaa gagttgatga aaaatcaagc acagtatgca gagctgtatc gcctgcaagc
    16501 tgaaaaatac gcgcagtaaa ggagaaagca atgagcaata tagaagaact tcgtctgttt
    16561 cgaaaagaag atattgaatg gctgcagacc tggtttgagg atgcagaagt gaaaaggcgg
    16621 ctggaaggga tgatgccact tgacgagtgg ttcaattttg caggcgggaa tgaaaactac
    16681 cgggtatggg cggctttaaa ggaaggcaag cccgtcggcg ttgtcatggt tgaagttgag
    16741 caagactcga ccgggaacat tgccctttta gtcgatccgt ttttgcgcgg agggggatac
    16801 ggaaaagcgc tcatcaaaag gacgatggca ttgccggaat tgagcaggat caacaagtgg
    16861 tttgccggga ttgaagaaga taacaagagg tgcttagcgt gcttcagatc agtcggatat
    16921 tcattggaac acgatcagcc ggatgaggac ggctactact ctcttattta tttcccggaa
    16981 tcttaaataa ggagcataag acgatgaact tgatcaaatg gattgttttt tccgttattt
    17041 cagtcgcctt ttttcagccg gcatcagccg ctctattaaa agaaaaggat gactatacca
    17101 ttcttgtata tatgattgga tctgacatgg aaagcgattt tcatatggca agcgatgata
    17161 ttcaggaaat gatggatgcc ggttcatctt caaacgtcaa tgtcgttctt cagacagggg
    17221 gagcaaaaaa atgggcgaac ccgtcgatca gtcacaaggt gaatcagagg tggaaagtcg
    17281 aacatcagaa actggtgtcc cttgaaaata tcgggaagaa aaatatggac agtcccagct
    17341 ccgtcacaga ctttatcaca tggggagtca aaaaataccc ggctaaaaaa tatgtattga
    17401 tcttctgggg gcatgggctt ggctccgttg acggctacgg gggagacgaa aacttcggca
    17461 ataagaaaat gaaaataagc gagctccagt cgggaatcaa aaaggcttat gaacatacga
    17521 agcaaaagtt tgatttaatc ggttttgaca actgcaaaat ggccgggatt gaaacggcat
    17581 atgccttaaa ggattatgga aggtatatgc tggcttcggt cgactatacg aaccaaaacg
    17641 gctgggatta caaaagggcg ctgcagtctg ttcaagacga cccttctatc gatccgaaag
    17701 aacttggcag ggaaatcgct gcaggctaca tacagcagtc aaaagaaaac ggtgaaacag
    17761 aagacctgca gcagtctttc attcaattga accgcgtcaa agacgctgtt gatgccctcg
    17821 acagattgag cttaagcatg aacagggcat tgaaagagcc ggatggaaag cgcctgcttc
    17881 actacgcacg tctcgctgct gaagattatg cagatgaatc ggatatggtt gatttggcgg
    17941 atttgtcaag cttgatcggt cagcagatcg gagctgaaaa agaagcaaaa gaggttgtaa
    18001 aatccgtcaa gaaggcggtc atcatgaaca tcaagtctcc ggagcaccca agaggaagcg
    18061 gtatgtccgt ttattatccg gccagagaca accaaaaatg gtttgcggaa aaatcaaaca
    18121 tataccacct ccttgacttc agcgcccggt atcaaacatt catcaaagat tactcacatt
    18181 caacatttaa ctttgattta tagttgcgtt taacagcaaa aaagcgccgg cggaaaaacc
    18241 ggcacttttt ttatcggctc atgtgcttcc ggatcaatgg aagtccgtaa atcatgaaag
    18301 cggcgacatg ggcgatgaca acgttgagaa taaagagtac gatcatgaga gagtgtcctg
    18361 taggagaaag gctgctggtc atatagaaaa agaagaatac ccacattaaa atgatcggcg
    18421 gaatagaaga aattgcgacc tttttgttgt ccagccataa aaataaagga gtggcgcttg
    18481 caatcagcaa gtaagcgaaa aacatatcca tgcgttttca gcccctttcg ataatgatag
    18541 cgctgtcaaa aaaagcggaa caaaacatta attgtgtcta attggagaat attttgtgaa
    18601 cattctgtta catttattat accacgttct tcgaaaaatg atacatactg gaaagcattt
    18661 tccgctccaa ctatcggctc aattttcacg gcgattcagt aggacataaa gggtgaaggg
    18721 gagaagaagt gaatagcgaa aatgtgtgga ggagattgat catgcgaaag ttagccaaga
    18781 accgcacgtt tcctatacga agccggcagg cttacgggaa gcgaagaaga agtaaacagg
    18841 ctggattgca cgataaggcc gcagacgcct tggatcaacg atttattcta aacaaaaaag
    18901 gccctcggca tttagcgccg ggagcctttt atttgtctaa aaaataaagt gggcacacaa
    18961 tacgatgacg ggcagcgtaa taagcgtccg aacgagaaaa atcaagacga ggtcaaggaa
    19021 tgtcaccggg attttggaac cgagcaaaag accgccgact tcggacatgt agattaattg
    19081 tgtaaccgat acacaggcga tgatgaacct ggtcatttcg ctttcaatcc cgcttccgag
    19141 cacagacggc aggaacatgt cggcaaaccc gacgacaagc gtttgtgagg cctcagcggc
    19201 ttcaggaacc tgcagcagtt cgagaagggg gatgaacggc agtccgagcc atttgaaaac
    19261 cggcgtatat tcagcgacaa tcagtgcggc tgtgccgagc gccatgacga cgggagcgac
    19321 gcccatccac atatcgagca cgtttttggt tccgtcccgc aagaaatctt tgacgcttgt
    19381 attctgtttt gcttttgcga cagcccggct gagtccccat tggaatggag tgtatccgtc
    19441 gggaatctcc tcttgatcat gatcagcttg atctgtaata taagtatcag cctttcttga
    19501 taaaggagga atccgcgggc tgatcaccgc agctgcggca cccgccagca atatcgtcaa
    19561 ataaaatgga acgaacatat gagcaaggcc aacttgtgaa ataatcacga ggcaaaacgt
    19621 gatggagacg actgagaaag tcgtgccgat gacggcggcc tcacgcttcg tgtagaaccc
    19681 ttcttcatac tgtttgcttg tcaggagcac gccgatcgtg ccgtcgccga gccatgaagc
    19741 catacaatcg atcgatgacc gtccaggcag cttaaagact ggcctcatca gttttttcat
    19801 caaagcgccg cacagttcga gcaagccgaa gttcaacagg aacggcagaa aaaggcctgc
    19861 aaatagaaag acggagaaga gaacgggaag caggctgaat aataatgttc cgccggtact
    19921 cttggcatac accgcttcag gtccgatctt aaagtacgcc atcactgcga aaatcatgcc
    19981 gaacaggcgg acgatatacc aaaataaaga tacattcagc aggttataga aaaactcgct
    20041 ttttttgatg aaagccggat gaaaggtttt agtgataaag gttaagataa atgttgcggt
    20101 tacgataacc gtcatgatta acggcaattg ctgctgaagc agcttctgca atgcatttga
    20161 aaaaacagca attggaatcg ttaaatttcc ttcaatttta acaggaatca taaacagaat
    20221 aattccgata agagaaggga ccaaaaattt tatgagatca agccgtttac gcttttgaag
    20281 tgctttatcc aaatgaaaaa ctccttatga attggtgatt ctgtaccact tctgccggag
    20341 gcaaaagttt aattttatgc aacattactc attttaatac aaatcaatca aaaatcaatg
    20401 aatttatcac attcgacaat agttggaaaa atcctttaaa atagaatagg aatttgttcg
    20461 caataaaatc gaaacatttt ggtcttctgt acgtcatatc atttgtgagg aagcggatgc
    20521 cgtcttcctg cattatttca tcgtgtcata ttataagggc gggatttcga atgagtcaga
    20581 aaaagaatat tacaaatccc ttttaccagg gggatttgat ttttgtttat attgtctttt
    20641 ttatcatcag cgttgtggct gtgtacgctg ctcagcagtt taatcaatat aatgaaccct
    20701 ttgcgatgaa acagtccctt tactatttac tgggggcctt catcatcatc gtgtttcttt
    20761 attttgattt ggagcagctt gaaaagctca gcttttattt ctatctgctc ggcattttga
    20821 tgctgatcgt gttaaagttc agtccagcat atatcggatc atacaggttt gcgccggtca
    20881 tcaacggtgc caaaagctgg tttatgcttc ccgggtttac gctgcagccg tcggaattta
    20941 tgaaaatcgg gctgatcatg tacttggctt ccttcatgtc taaaaacggg cctgtcggca
    21001 agcgtacgtt gaaagaagac tggatttttc tgctgaaaat cgccggtatt atcattgttc
    21061 cgttcggctt gattttagag caggatacgg gtacagccgg gatcgtcgcg tttgtgatcc
    21121 ttgtgatggt attcctgtcg ggcgtgaact ggaaattgat ttctctcatc tttggaacgg
    21181 gtcttgcagc cgttgttttg attttgtttg tcattatcaa atttcccgat gtcgcgggcg
    21241 cactcggggt tgaaccatac caaatcaacc gcgtcatgac ctgggtcaat ccaagtgaac
    21301 aaaatgccga cgataaaatg caggtcgaaa gggcgcagct ggcgatcggt tcgggaaaag
    21361 tattcggaaa tggtgtaagc gatcttcaag tctatgttcc tgaagcgcaa acagacttta
    21421 tttttgccgt catcggcgag agcttcgggt ttgtcggatg cacctttgtt gtcattatgt
    21481 ttttcttctt aatttaccgg cttgtcgtgc tcatcgaccg aatacatccg ttcagcaggt
    21541 ttgcctcatt tttctgtgcg ggctttaccg ctttaattgt cattcatacc tttcaaaata
    21601 tcggaatgaa tatcggcatt atgcccgtga ccggcgtccc gctgcttttg gtcagctacg
    21661 gaggcagctc agtcgtagca accttgatcg gcttcgcggt tgtctacaat tcaagctgcc
    21721 agttaacaaa gtatcaaagc tatatgttca aataacagcc tgatgtatgc aggctgttat
    21781 tttattcacc ctttttcaca atgtgaacga ttgttcatgc tataatgaaa gttagtgctt
    21841 ttgatgaaga aataaggcgg ggtataatgg gccagaagaa aaatacgaca agtccctatt
    21901 atcagggaga tttgattttt atattagcca tgttcttttt gatcagtgtg atcgctgttt
    21961 acgctgcaga gccgtctttt tcactgaagg gttatccggc aaagcaatta ttcttttatc
    22021 tgctcggcat gtcggtgatc gtcggctttc tctattttga tctggagcag cttgaaaaat
    22081 tcagcatata catatatcta ttcggcattt tgtcattgat cgtcttaaag ttcagtccac
    22141 cgtcgatcgc cccggttatc aaaggagcga aaagctggtt tcaatttggt tcgatcacgc
    22201 tgcagccgtc ggaatttatg aaaatcggcc tgattatgat gctggcttct gtgatttcca
    22261 aagcaagtcc gaaaggctcg cgctcgatgc aggaggatgt tcgcctgttg ctgaaaatcg
    22321 caggggtatc ggcggttccg gtcggtttga ttttaatgca ggacgccggt acggccggta
    22381 tttgcatgtt ctttgtcgcc gttatggtgt ttttatcagg tgtgaactgg aagctgattt
    22441 tcatcgtggc ggggtcagga atcatgctcg tactgctcgt tctgtttttg gtgatcaatt
    22501 ttccggagtt ttcaaaggat acgctgcata tccagcaata tcagatcaat cgggtgatga
    22561 catgggtcga ttcgagccag caggacgcga acgatacgta tcagaccgaa aaagccgtta
    22621 cggcgatcgg ctctggagaa attttcggaa tgggcatgaa caatttgaaa gtatacgttc
    22681 ctgaaggcca aaccgatttc atctttgccg tcatcggtga aagtttcggc ttta
//
