LOCUS       NZ_JALAJC010000005     10869 bp    DNA     linear   CON 23-JAN-2024
DEFINITION  Bacillus inaquosorum strain S8C1X1 contig_0000005, whole genome
            shotgun sequence.
ACCESSION   NZ_JALAJC010000005
VERSION     NZ_JALAJC010000005.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus inaquosorum
  ORGANISM  Bacillus inaquosorum
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 370795)
  AUTHORS   Dunlap,C.
  TITLE     Crop Bioprotection Bacillus Genome Sequencing
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 370795)
  AUTHORS   Dunlap,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-FEB-2022) CBP, USDA-ARS-NCAUR, 1815 N. University St.,
            Peoria, IL 61604, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC NGS Cell v. 21
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 228.72242007437796x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/23/2024 03:13:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,417
            CDSs (total)                      :: 4,337
            Genes (coding)                    :: 4,218
            CDSs (with protein)               :: 4,218
            Genes (RNA)                       :: 80
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 82 of 119
            Pseudo Genes (incomplete)         :: 62 of 119
            Pseudo Genes (internal stop)      :: 20 of 119
            Pseudo Genes (multiple problems)  :: 35 of 119
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:37:44
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 270143
            Orig. end                         :: 281012
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JALAJC010000005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..10869
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="2"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..10869
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10869
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5869](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5869)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     misc_feature    complement(1400..1415)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 22.02"
                     /tool="antismash"
     gene            complement(1510..1740)
                     /locus_tag="MOB18_RS08975"
                     /old_locus_tag="MOB18_08940"
     CDS             complement(1510..1740)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006831286.1"
                     /locus_tag="MOB18_RS08975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB18_08940"
                     /product="hypothetical protein"
                     /protein_id="WP_268290408.1"
                     /transl_table=11
                     /translation="MLWLITQNKQSLVNVKEVTVNGKSLEGIMGSASLDQWSKTLGKYE
                     SNERALEILNEIYMKIEESKGISVVFSMPLK"
     gene            complement(1841..2023)
                     /locus_tag="MOB18_RS08980"
                     /old_locus_tag="MOB18_08945"
     CDS             complement(1841..2023)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026318.1"
                     /locus_tag="MOB18_RS08980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB18_08945"
                     /product="hypothetical protein"
                     /protein_id="WP_268290407.1"
                     /transl_table=11
                     /translation="MSVSFTNIISITAIVIWIAVFLELKKSSKEKNGRKIITLISIGVI
                     LTLVMTVSLIRNIQT"
     gene            complement(2236..2742)
                     /locus_tag="MOB18_RS08985"
                     /old_locus_tag="MOB18_08950"
     CDS             complement(2236..2742)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008354991.1"
                     /locus_tag="MOB18_RS08985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB18_08950"
                     /product="hypothetical protein"
                     /protein_id="WP_268290406.1"
                     /transl_table=11
                     /translation="MEKYAKLTSFISLILYMLINFYFISLTIEINGFSEQLKDLDELLD
                     NISHEKIVLIISIVTTVITMISLLVQYIIGKFLLIIFVSNVKSHLFYALIPKILIMIIN
                     IVFIGVWQIHNSWLYMFTALMGSIVILLFFQYKKENWKASILFAAAFIIDALISLGKEI
                     FSLIL"
     gene            complement(2721..3335)
                     /locus_tag="MOB18_RS08990"
                     /old_locus_tag="MOB18_08955"
     CDS             complement(2721..3335)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008354993.1"
                     /locus_tag="MOB18_RS08990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB18_08955"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_268290405.1"
                     /transl_table=11
                     /translation="MSLEFVECTKKFKNNLILDKVNFKISKGLFNLTGRNGAGKSTLLK
                     MISGLDKKYSGNIIANNKSTLYLNVDPIGIHPFTIKENLEILWNTFNITPSTKQLSKVN
                     DFFDDNLDVSYSRASTGMKAKLGLSLIFVKDWETILIDETMSSLDSESIDMLAESLVNL
                     SAKEISTIIYVSHSMVNVHLKDNSSAICIGEGNLSWKNMQS"
     gene            complement(3356..3889)
                     /locus_tag="MOB18_RS08995"
                     /old_locus_tag="MOB18_08960"
     CDS             complement(3356..3889)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012011575.1"
                     /locus_tag="MOB18_RS08995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB18_08960"
                     /product="stage II sporulation protein M"
                     /protein_id="WP_326849895.1"
                     /transl_table=11
                     /translation="MHHNFHYCFVKRGAKMIHNRFKCFLLYYFIYCLLIISIGVFLGAI
                     VNKNLFKPEPLSLDHDFMFLVLSHNLRNFIMYLLAFIVSPILQLLDFGGSAFQITIGFR
                     TLGTQEALNRLIPHGLLEFPNMLLYQGISQYMLFTLIFTRSIKMTLDVMKKMIPFYLLS
                     LIILIIAAILEGYI"
     misc_feature    3881..3894
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 20.8"
                     /tool="antismash"
     gene            complement(5001..5291)
                     /locus_tag="MOB18_RS09000"
                     /old_locus_tag="MOB18_08965"
     CDS             complement(5001..5291)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR03651"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008343460.1"
                     /locus_tag="MOB18_RS09000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB18_08965"
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="WP_268290403.1"
                     /sec_met_domain="TIGR03651 (E-value: 1.1e-16, bitscore:
                     55.4, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKVKDSKFYALLSVSLFAVTLVALAIGNGPLIAAQLGLSTATSW
                     TIVNFLDGVSSVATVISIIGMFTGVGTIGSAFAATLLAILKKQGKAKAAAF"
     gene            complement(5579..5869)
                     /locus_tag="MOB18_RS09005"
                     /old_locus_tag="MOB18_08970"
     CDS             complement(5579..5869)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR03651"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008343460.1"
                     /locus_tag="MOB18_RS09005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB18_08970"
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="WP_268290402.1"
                     /sec_met_domain="TIGR03651 (E-value: 1.5e-18, bitscore:
                     61.5, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKVKDSKFYALLSVSLFAVTLLALAIGNGPLIAAQLGLSTGTAA
                     TIVNFLDGVSSVATVISIIGMFTGVGTIGSAFAATVLTILKKQGKAKAAAF"
     gene            complement(6533..7012)
                     /gene="rlmH"
                     /locus_tag="MOB18_RS09010"
                     /old_locus_tag="MOB18_08975"
     CDS             complement(6533..7012)
                     /EC_number="2.1.1.177"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /gene="rlmH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391903.1"
                     /locus_tag="MOB18_RS09010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB18_08975"
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="WP_003243164.1"
                     /transl_table=11
                     /translation="MNINIVTIGKLKEKYLKQGIEEYTKRLSAYAKIDIIELPDEKAPE
                     NLSDQDMKIIKDKEGDRILSKISPDAHVIALAIEGKMKTSEELADTIDKLATYGKSKVT
                     FVIGGSLGLSDTVMKRADEKLSFSKMTFPHQLMRLILVEQIYRAFRINRGEPYHK"
     gene            complement(7093..7263)
                     /locus_tag="MOB18_RS09015"
                     /old_locus_tag="MOB18_08980"
     CDS             complement(7093..7263)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_003097800.1"
                     /locus_tag="MOB18_RS09015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB18_08980"
                     /product="CxxH/CxxC protein"
                     /protein_id="WP_003236479.1"
                     /transl_table=11
                     /translation="MKQTYYSCEEHIETVLDMYIDDHELPPEIRKIEHTNSLSTACELC
                     GDPAVYIVGNE"
     gene            7448..7858
                     /locus_tag="MOB18_RS09020"
                     /old_locus_tag="MOB18_08985"
     CDS             7448..7858
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391904.1"
                     /locus_tag="MOB18_RS09020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB18_08985"
                     /product="hypothetical protein"
                     /protein_id="WP_268290401.1"
                     /transl_table=11
                     /translation="MRFKWVWLFVIMLLLAGCQSSYWVLEKDRIDEVPDIKSYVKDLQM
                     HDDVKGYQVFTISEGKKMVVVSLGSSDKAKKLEMSDVKFSPKETIVTVTRKPAPKANEK
                     NPYILIGLDKIEGDLIVQDESGDRFEETDYQQ"
     gene            complement(7892..9118)
                     /gene="fdhA"
                     /locus_tag="MOB18_RS09025"
                     /old_locus_tag="MOB18_08990"
     CDS             complement(7892..9118)
                     /EC_number="1.2.1.46"
                     /GO_function="GO:0018467 - formaldehyde dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0046292 - formaldehyde metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fdhA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391905.1"
                     /locus_tag="MOB18_RS09025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB18_08990"
                     /product="formaldehyde dehydrogenase,
                     glutathione-independent"
                     /protein_id="WP_268290400.1"
                     /sec_met_domain="ADH_N (E-value: 4.6e-26, bitscore: 85.5,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 8.3e-12, bitscore:
                     39.8, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGGMVLTGNKAVVYKGKGTVAVEDVGYPELILKDGPGVPKANVNR
                     KCEHGVILKVITTNICGSDQHMVRGRTTAPEGLVLGHEITGEVIETGRDVEFIKKGDIV
                     SVPFNIACGRCVMCRTQKTHVCLNVNPDRPGSAYGYVDMGGWVGGQSEYVMVPYADFQL
                     LVFPDKEQALEKILDLTMLSDIFPTGFHGAYTAGVQTGSTVYIAGAGPVGLAAAHSAQL
                     LGASTVIVGDLNEDRLAQARSFGCATVNVKKHDRLGEQIEQILGEPTVDAAVDCVGFEA
                     SGHGNQGEAPAAVLNSIMDVTQVGGSLGIPGLYVTEDPGAKDADAKTGSLKIRFGLGWA
                     KAHTFVTGQTPAMTYNRNLMKAILSGRAQIAKAVNATVISLDDAPKGYSDFDKGAAKKF
                     VIDPHGTLK"
     gene            complement(9181..9351)
                     /locus_tag="MOB18_RS09030"
                     /old_locus_tag="MOB18_08995"
     CDS             complement(9181..9351)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_003097801.1"
                     /locus_tag="MOB18_RS09030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB18_08995"
                     /product="hypothetical protein"
                     /protein_id="WP_268290399.1"
                     /transl_table=11
                     /translation="MHTKRVILLAVIISLISAATMFLLNGGKADWLDILGIIIGCFLGI
                     FVVLRIQKKQA"
     misc_feature    9312..9326
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: weak, score: 16.85"
                     /tool="antismash"
     misc_feature    complement(9356..9372)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 21.16"
                     /tool="antismash"
     misc_feature    complement(9485..9498)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 21.93"
                     /tool="antismash"
     gene            complement(9560..9799)
                     /locus_tag="MOB18_RS09035"
                     /old_locus_tag="MOB18_09000"
     CDS             complement(9560..9799)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003236486.1"
                     /locus_tag="MOB18_RS09035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOB18_09000"
                     /product="DUF2651 family protein"
                     /protein_id="WP_268290398.1"
                     /transl_table=11
                     /translation="MGVIAVLLIVFGFPIIAGVFGIAGHFLFKRFWVAPLIVLMASIIL
                     LFTLASGNSSFLFWVVLYTAIALVTSVVTLFLRK"
ORIGIN
        1 ccataaacac ttcaactcaa aggcagaagt cctaagcacc ggaaccgacg tcttaacagt
       61 gaagcgatta gtggataaag agcttgagcg gaagaaagtg aaggaaacga atgttggtga
      121 ggaactgttg caggaagttg cgattttgga gagtttgcgg gagtatcggt atatgaagtg
      181 aggggtgtgg ggttcaggga ttatattctc ccctataggt aaacagataa aagaagaaat
      241 ctggttgcct taggggagtt ttttcatggc tgaaaaaatc gcactaaaaa gaagaaaaaa
      301 caactaaact caatcagaat gtgatcagga gaatactcga cgaaagatag attggaataa
      361 tatgcaaatc aaactgtgat agtcccatta acagagaaca tttcatgata cacttgatgt
      421 tgacagtcca gaatgttcag ttctctcttc ggaactgaac cacgttgcca tgaaaaattc
      481 ttatacggac actactctca aagatgagag aatattaaaa ttctagtaaa tccatgctaa
      541 gaggatggac tgaactttat gagatggtca taaagcgtaa aaaaggggag tggaaggaat
      601 cattttatga ccaaatggaa gaaactcgct tctcaaaaaa tggaacattc ctctttttca
      661 ctaactatgt gacaattgca gttaaatgca ttggagcaat gtttaaagga aactatatga
      721 gtaaataaaa agcaaacaca aaaactaaat tttaatataa atctatttcc aaactgtttt
      781 aaataaacca ttgttgtttc ctttcaccat tttataaaac gaaagaagat tgttaatatg
      841 ataaaataat taatcggatt ctaatatact tatctctact gaaatctgga agatggctag
      901 tattatttga ttgatatttt gtactttttg actacataaa gatttataat aaacataact
      961 gtgttattcc ttttatatca ataacaatag tcaaaaataa aaagcaaaat atgatcagtt
     1021 gcaacgtact cttttataca atactgttac aatttctaca gatttctact tgcaaacttt
     1081 agaagatctt tttaattaaa tccatttgaa atattatata cgaaatcatt acacacgcga
     1141 tcttctagtc tcggaagaag aaaaattaga ttttataatt agtttttctg atttgtttct
     1201 tcatgtggga gggcttactg aggcagagta agagcgttgg gaggtaagag agatgaactc
     1261 gaaaatttat atttagagta ttttttaact gattaatgtg ttgccgtttg attactaaat
     1321 agtctctttt ctttcaaggt ttctttaagg tataatttat aaaatgcttg attgtcaaca
     1381 caagatgtct aattgtgtgt tgacaatccg gtcaacttgt atagtaggag tttataaaaa
     1441 cactccttta atattaaaac taaattattt ttcttaccaa tctcgctcta ttattgatta
     1501 agatgatact tattttaggg gcatagagaa aaccacagaa atacccttgc tttcttcaat
     1561 tttcatatat atttcattaa gaatttccag tgctctttcg tttgattcgt attttcctaa
     1621 agttttactc cattgatcca aagatgcact gcccataata ccttctaaac ttttcccatt
     1681 tacagtaact tcttttacat taactaaact ttgtttattt tgtgtaataa gccacaacat
     1741 caaaaactct cccttcaatt aattatttta tatcatatct taacccggtt agggcacttt
     1801 tttattcgat tatcgtccaa ttatgaaatc tttaaataaa ttaagtctga atattgcgaa
     1861 taagtgaaac agtcataact agagttaata tgacacctat agatattaga gttattattt
     1921 ttcgtccatt tttctctttt gatgattttt ttagctctaa gaacactgca atccatataa
     1981 ctatagccgt tatcgaaata atatttgtaa aagaaacaga cattttgaca ctcctcttta
     2041 caggtatcgt atgggcaatt cactcagaca ttgtatttta tctatgccca gactacctga
     2101 atgctgtatg ttcgtcaact ccaaactctt gttcagatcc tcctccttgt gataaccatt
     2161 gccaattaag atgcccggtg cataagtttt aagtgatata ttcctttaat ttttagaaac
     2221 aaccttatca ctcttctata atatcaatga aaatatttct ttccctaatg aaattaaagc
     2281 gtcaattata aaagctgctg caaagagaat tgatgctttc cagttttctt ttttatattg
     2341 gaaaaagagc agtattacaa tagatcccat aagagcagtg aacatataca accatgaatt
     2401 atgtatttgc caaaccccga tgaaaactat attaatgatc ataatcaata ttttagggat
     2461 aagagcataa aacaagtgac ttttaacatt agaaacaaaa ataatcaaca aaaatttacc
     2521 gattatatat tgcaccaaaa gactaatcat tgttataact gtagtaacta ttgatattat
     2581 caggactatt ttctcgtgag aaatattatc taataattca tccaaatctt ttaactgctc
     2641 agagaaccca tttatttcaa tagttaaaga aataaaataa aaatttatga gcatgtataa
     2701 aatcagtgag ataaatgatg ttagctttgc atatttttcc acgacaggtt cccctctcct
     2761 atgcaaattg cacttgaatt atcttttaag tgtacattta ccatgctatg agaaacatag
     2821 attattgtcg atatctcttt tgctgaaaga tttaccaggc tttcagctag catatcaata
     2881 ctttctgaat ctaaagatga catagtttca tctattaata tagtctccca atccttaaca
     2941 aaaattaatg ataaaccaag tttagctttc attcctgtag atgctctact atatgaaacg
     3001 tctaaattat catcaaaaaa atcattaact ttggatagtt gttttgtaga tggagtaata
     3061 ttaaacgtgt tccacagaat ctctaggttt tctttgattg tgaaaggatg gataccaata
     3121 ggatcgacat ttaagtacaa agttgatttg ttatttgcaa taatattacc tgaatatttt
     3181 ttatcgagac cagaaatcat tttaagaaga gtactcttac ccgcaccatt acgacctgtt
     3241 agattaaaaa gaccttttga tattttaaag ttcactttat ctaaaattaa attgtttttg
     3301 aattttttag tgcattccac aaattctaaa ctcacatgaa tcccctttct ttaatttaaa
     3361 tatacccttc aaggatagca gctattatta atattattag tgataataaa taaaaaggaa
     3421 tcattttttt cattacatct agagtcatct ttatcgacct agtaaaaatt aaagtgaaaa
     3481 gcatatactg actaattcct tgatatagca acatatttgg aaattccaat agtccatgtg
     3541 gaattaatct gtttaaagct tcttgtgtac ctagagttct aaaacctata gtaatttgaa
     3601 aggctgaacc cccaaaatct aataactgca ggattggcga gactataaaa gccagtaaat
     3661 acattataaa gttccttaaa ttgtgcgaca aaactagaaa catgaaatca tggtccaaag
     3721 aaagtggttc tggtttaaat aaatttttat taactatggc tcccaaaaaa actcctatac
     3781 taataattaa taaacaatag ataaaatagt ataataaaaa acatttgaat ctattatgta
     3841 tcattttcgc tcctcttttc acgaaacaat agtgaaaatt gtgatgcata tcaacattaa
     3901 aataggcagg gttaatttta ataagttgtt ctcatagcca ctagttaaca actcagtttt
     3961 tctaaaatat acaatcccta taaaaaatat taaaggaatt gataagagat ttttaagaat
     4021 tattgtaata tcagacgtat ttaatattac ccctactaat ccacatacac atacagcaaa
     4081 taacataaga gatattaaat aaatggaact tgatttaaat ctattaaatg agcttacaat
     4141 taaagaggat tgtaaagttt ctactcgtgc tttatcaagc ataatctctt cgctttttga
     4201 ccctattaaa atttctaaga tagtcataaa gttaacataa acgattatta acgcagggag
     4261 tccttgtata ttagttaaaa atagttgact aaaataagtt atcacggata ccaggacccc
     4321 aagcaaaacc attaatatct tattattgat tatataagac aaatatatat ataaaatatt
     4381 tcctgacgaa tatcctttat tagaactatt taaaaatgat aatccacagg gagaaggtat
     4441 actttggaat ttaattatat agaagcaaat aataagtaat tgtataatta aaaccactac
     4501 agataattta aatgaaaaag atattacgaa ccaaaattgt aataaaaaaa gtaatctgat
     4561 tattatattg aacaagccag atgttaattc agacataaag gaaatcacta cagtactcaa
     4621 ggctaatata ataataaaat actgatttaa tataaacata aaggttatag atataataca
     4681 agcaagaagt aattgtagtg aatagccttt tttaactgta aaaaacagat gcttcaataa
     4741 taagcgttta gaagtgaaga ccaaaccagg ttgttgtttt ctatacggta atatacaacg
     4801 gttaatattt gctgttgcta caatatatat cgaaataaaa gaaaatataa ttaggtgttg
     4861 gctgggaacc aaatcatgat gaaaaatcag cgctagaata atgagtgatg aaaaaagaat
     4921 catcccaata taattgagat gacctattat actttgatca taaagtttaa atagtctctt
     4981 tatcatatgc ataagttctt ttaaaaagca gctgctttag cttttccttg tttcttaagt
     5041 atagccagaa gagtcgctgc aaacgctgaa ccaatagttc ctacacctgt aaacattcca
     5101 ataatagaaa taactgtagc tactgaggag acaccatcca aaaagttgac aattgtccac
     5161 gaagtcgcag tactaagtcc tagttgggct gcgatgagtg gtccgttacc aatagctaga
     5221 gctactaatg taactgcaaa aagtgatact gataacagag cataaaactt cgagtccttt
     5281 actttaacca tgaaattacc tcctattttt atttactaca ctcatagtat aaccaaaaaa
     5341 aaaacagcga tcaacaattt ttggaaaatg atcttttata ttgaatttaa gcaaattaat
     5401 ttcctgtcac tgctaattaa tcttagttac taccttagcg atttaacgtt aactgctatc
     5461 aaactatcta acaaaatata agtagaatag tgatgaaaaa agaatcatcc caatataatt
     5521 gagatgaccc ttcttatttc aattgtaagg ttttaaaagg tttatgtctt aaaaataatt
     5581 aaaaagcagc tgctttagct tttccttgtt tcttaagtat agtaagaaca gtcgctgcaa
     5641 acgctgaacc aatagttcct acacctgtaa acattccgat aatggaaata actgtagcta
     5701 ctgatgaaac accatctaaa aagttgacta ttgttgctgc agtcccagta ctaagtccaa
     5761 gttgagctgc gatgagtggt ccgttaccaa tagctaaagc taataatgta actgcaaaaa
     5821 gtgatactga taacagagca taaaacttcg agtcctttac tttaaccatg taatcacctc
     5881 ctattttttt actacactct tagtataaca aaaaaaataa aacaatcaac attttttgga
     5941 agaaaatctt ttaaaatcta tttatagaaa tttaaacctt taattgaatt attaatctct
     6001 cgctgtatct tatttttaac gttaaatact ctaaaacagt gcaaagtctt tatacagcac
     6061 gaatgtatta aatcgcatga ttcatatttt agaaaaagat caaatgagac accccgtgga
     6121 aactcacaat tcaatacttt ttcatcagtt actcaatata gtttagttag aaaaatataa
     6181 ataactttta ttaatcacag cgagcagttt gggtattctt tcttttgctt ctttttatgt
     6241 gtctataact agaacaaatc attacatctt cttaaaccat tttcttttag gattgagttc
     6301 tgtaatacgc tattaatgtc aatgatttct ttactattgt cgttactagt atactgttca
     6361 gagatttttt tcatttatgt ttttgttata gcgtgggagt aactaactaa gcctcctgct
     6421 ctgggttata aaagaaatat cttttttagt tttttataat tcacttcaat tctcttgata
     6481 aatgtttcca agaactgtct gaactccata actccctcta gaaaactgct acctatttat
     6541 gataaggctc cccacgatta atccgaaaag cccgataaat ctgctcgact agtatgagac
     6601 gcatcaactg atgagggaac gtcattttcg agaacgacag cttctcatcc gctcgcttca
     6661 tcaccgtgtc actcaatccg agtgatccgc cgatgacgaa ggtgacttta ctttttccat
     6721 aagtagccag cttatctatt gtatcggcta gttcttcgga tgttttcatt tttccttcga
     6781 tggcgagggc gatgacgtgg gcgtcggggc tgatttttga tagaatgcgg tcgccttctt
     6841 tgtcttttat gattttcatg tcctggtcgc ttaggttttc cggcgctttt tcgtccggga
     6901 gttcgatgat gtcgattttt gcgtaggccg aaagtcgttt tgtgtattct tcaatgcctt
     6961 gcttgaggta tttttctttt agttttccga ttgtcacaat attgatattc acaggtcatc
     7021 cccactttaa aaacaagtta ttcatatatg ttgtccacaa ttgtggatat cttttctgta
     7081 ttttgtgtaa gatcattcgt tccccactat atatactgcg gggtctccac ataattcaca
     7141 ggctgtggat aaactgttag tatgttcgat ttttctgatt tcgggcggca gctcgtggtc
     7201 gtctatgtac atatccagca cggtttcgat gtgttcttca caggaataat acgtttgttt
     7261 catgttcaaa tcctccgatg gtttcttgca tttttgcaaa tattctcttc ccaatataac
     7321 ctatttattc acatgttagt agtgcttcgg gctgagtttt atccacaatt cgacaaacaa
     7381 gctgttgatg actctatctc gctcgtatgt taggttggat gtaaacgatg tttggggagg
     7441 tctgcgtttg cgcttcaaat gggtttggct ttttgtgatc atgctgttgc ttgctgggtg
     7501 tcagtcgtct tattgggtgt tagagaagga ccggattgat gaggttccag acattaaaag
     7561 ttacgtgaaa gatctccaaa tgcatgatga cgtaaaagga tatcaagtct ttaccatttc
     7621 agaaggcaaa aaaatggttg tggtgtctct cggaagcagc gataaggcta aaaagcttga
     7681 gatgtcagac gttaaattct cgcctaaaga aacgattgta actgtgacgc gaaaacccgc
     7741 tcccaaggca aatgagaaaa acccttatat tctgattgga ctggacaaaa tcgaagggga
     7801 tttaatcgta caagacgaat caggagatcg ctttgaagaa acagattacc agcaataaag
     7861 ccggcgttcc gagaacgtcc ggctttttat cttatttcag cgttccatgc gggtcgatga
     7921 cgaatttttt ggctgcgcct ttgtcgaagt cgctgtagcc ttttggcgcg tcgtccagag
     7981 agataacggt ggcgttgaca gcttttgcga tttgcgctct gccgctcagg attgctttca
     8041 tcaaattgcg gttgtatgtc atggcaggtg tttgtccggt gacgaaggtg tgggctttgg
     8101 cccagccaag tccgaagcgg atttttaatg agcctgtttt ggcgtccgca tcctttgcac
     8161 cgggatcttc ggtcacgtat aagcctggaa tgccaaggct tccgccgacc tgggtgacgt
     8221 ccatgatcga gttcagcacg gcggctggcg cttctccttg attgccgtgc ccagacgctt
     8281 caaagccgac acagtccact gcggcatcca cggtcggttc acctagtatt tgttcaattt
     8341 gctcgccgag gcggtcgtgt tttttcacgt tgaccgttgc acagccgaag cttctcgcct
     8401 gtgccagtct gtcttcgttc aaatcgccga caatgaccgt cgaggcgcca agaagctggg
     8461 cagagtgagc agcggctaag ccgacaggcc ccgctcccgc gatatagacg gttgaacctg
     8521 tttgcacgcc cgctgtgtac gccccgtgga agcctgtcgg aaaaatgtcg gataacatgg
     8581 tcaaatcgag aatcttttct aacgcctgtt ctttatcagg gaataccaaa agctgaaaat
     8641 cggcgtacgg caccatgacg tattccgact gtccgccgac ccagccgccc atatcgacgt
     8701 agccgtaagc cgatcccggc cgatccggat tgacattcag gcatacatgc gttttctgcg
     8761 ttctgcacat gacacagcgc ccgcaggcaa tattgaaagg aacggataca atgtcgcctt
     8821 ttttgataaa ttcaacatcc cgccccgttt caatcacttc tccggtgatt tcatgcccta
     8881 gcactaagcc ttcaggcgcc gttgtgcgac ctcgcaccat gtgctggtcg cttccgcaaa
     8941 tgttggttgt aatgaccttc aaaataaccc catgctcaca tttccggttt acattcgcct
     9001 tcggaacgcc gggcccgtcc ttcaagatta actccggata accgacatcc tccaccgcta
     9061 cagttccttt gcctttgtac acaaccgctt tgtttcctgt caacaccatt cctcccattc
     9121 atgtttttgg actcttggtc cttgaacatg acttcggttc ggcatgaccc tttccctttt
     9181 tcacgcctgc tttttctgta ttcttaaaac aacaaatatg ccaagaaaac agccgataat
     9241 gattccgagg atgtccaacc aatctgcttt acctccgttt aacaggaaca tcgtagccgc
     9301 cgaaatcaga ctgatgataa cggccagaag aatgacacgt ttggtgtgca tatgattcct
     9361 cctttatctg catccatttt atatatttat tttacaacaa ttaacacttt gtttgtttta
     9421 aaaggccatt cgagatttat agttttgaac cacgtttaga tggaggctgg acaacgttct
     9481 atcattgata tgtatcaaat tgcgtaacag aaaaaagaga cttcacaagt ctcttcataa
     9541 acagcgatca gttgaataat catttcctga gaaataatgt gacaacactg gttactaacg
     9601 caattgcagt atagagcaca acccaaaaca aaaatgaact gttgccagat gctaatgtaa
     9661 acaacaaaat gatgctcgcc attaggacaa tgagcggcgc cacccaaaat ctcttaaata
     9721 aaaaatgacc cgctatacca aatacacctg cgatgatcgg aaaaccaaaa acgattaata
     9781 aaacagcaat gactcccata ctaacctcct tgcccttaaa accccttcat cacctcaaaa
     9841 tcatacagct tcaaatgact cttcggcgtc acgatctcct ttaccttccc aatctctttt
     9901 tccttcactt tctttccggt tttcagactg tactgttcaa tgtatgcagg cttgttataa
     9961 ctgtatgtga agaaataaag gctgctgcct ttttgggtaa tttctctgaa atcggctttc
    10021 attttgtctc gggaaagggt gaaggcggtg cttgtttttc ctgtctttgc atcgattttg
    10081 tatccctttc cgaagccgtc aatgaagtac aagtgcccgt cataagggaa aaaacttctt
    10141 ttaaagctga agggcatgga gctgtatatc gtttgttcgt cgtttttgta ttcggcgatg
    10201 tcgtgcatct ctactttgca gctttttttg ttgatcttga ccatttgata aagattacga
    10261 gccttttggc cgcgaaccat aaaataaaca gcttgatcgt ccatggcaag ctgggattcg
    10321 actgaggctc cttcccggta ctgccattcc gttatcttgt gataagtgag cttcttttga
    10381 tctgcttgaa tctgaaggag ctcatagcct ttttcgtcag ctgtcgggac aagtgcataa
    10441 atggcgccgt catgaaaacc tgaggcgcgg atatagtagg ggatgacgtc ttttttccac
    10501 tctccgtcca tctggcggta cagctctgag cggtacccgt ctcccttttt gtcgtagccg
    10561 gagttgtaga gggtgtaaaa accgtccgta ttttgtagaa agcctgcgct gtcacctgtg
    10621 tgctgatagg ctcttttatg ggagctcagg ccgtctttaa tcgtataaat tgtgtttttg
    10681 tcctccagca tcacactgtc gccgtgaaca ttggctgagc ctagctcaag gcccttcatc
    10741 ttaaatgaag aaagcgacgc gtcttggctg ataaacaggg cgtagctttt cccgccgcca
    10801 aatgcatctt gatccgcaga ggatgagaaa tacagcaggg cttctttgtc atccagaaaa
    10861 tcgacgtct
//
