GCF_026782025.1 - 3 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

NZ_JAKVIE010000010.1 (Streptococcus pasteurianus)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1.1	T3PKS	8,528	49,706

NZ_JAKVIE010000017.1 (Streptococcus pasteurianus)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 8.1	lanthipeptide-class-i	1	22,542	High	suicin 90-1330	ribosomal:RiPP

NZ_JAKVIE010000005.1 (Streptococcus pasteurianus)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 33.1	terpene-precursor	98,780	119,649

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1.1	T3PKS	8,528	49,706
Region 8.1	lanthipeptide-class-i	1	22,542	High	suicin 90-1330	ribosomal:RiPP
Region 33.1	terpene-precursor	98,780	119,649

No secondary metabolite regions were found in these records:: NZ_JAKVIE010000011.1 (Streptococcus pasteurianus); NZ_JAKVIE010000012.1 (Streptococcus pasteurianus); NZ_JAKVIE010000013.1 (Streptococcus pasteurianus); NZ_JAKVIE010000014.1 (Streptococcus pasteurianus); NZ_JAKVIE010000015.1 (Streptococcus pasteurianus); NZ_JAKVIE010000016.1 (Streptococcus pasteurianus); NZ_JAKVIE010000018.1 (Streptococcus pasteurianus); NZ_JAKVIE010000019.1 (Streptococcus pasteurianus); NZ_JAKVIE010000001.1 (Streptococcus pasteurianus); NZ_JAKVIE010000020.1 (Streptococcus pasteurianus); NZ_JAKVIE010000021.1 (Streptococcus pasteurianus); NZ_JAKVIE010000022.1 (Streptococcus pasteurianus); NZ_JAKVIE010000023.1 (Streptococcus pasteurianus); NZ_JAKVIE010000024.1 (Streptococcus pasteurianus); NZ_JAKVIE010000025.1 (Streptococcus pasteurianus); NZ_JAKVIE010000026.1 (Streptococcus pasteurianus); NZ_JAKVIE010000027.1 (Streptococcus pasteurianus); NZ_JAKVIE010000028.1 (Streptococcus pasteurianus); NZ_JAKVIE010000029.1 (Streptococcus pasteurianus); NZ_JAKVIE010000002.1 (Streptococcus pasteurianus); NZ_JAKVIE010000030.1 (Streptococcus pasteurianus); NZ_JAKVIE010000031.1 (Streptococcus pasteurianus); NZ_JAKVIE010000032.1 (Streptococcus pasteurianus); NZ_JAKVIE010000033.1 (Streptococcus pasteurianus); NZ_JAKVIE010000034.1 (Streptococcus pasteurianus); NZ_JAKVIE010000035.1 (Streptococcus pasteurianus); NZ_JAKVIE010000036.1 (Streptococcus pasteurianus); NZ_JAKVIE010000037.1 (Streptococcus pasteurianus); NZ_JAKVIE010000003.1 (Streptococcus pasteurianus); NZ_JAKVIE010000004.1 (Streptococcus pasteurianus); NZ_JAKVIE010000006.1 (Streptococcus pasteurianus); NZ_JAKVIE010000007.1 (Streptococcus pasteurianus); NZ_JAKVIE010000008.1 (Streptococcus pasteurianus); NZ_JAKVIE010000009.1 (Streptococcus pasteurianus)

Compact view

NZ_JAKVIE010000010.1 - Region 1 - T3PKS

Download region GenBank file

Download region SVG

Location: 8,528 - 49,706 nt. (total: 41,179 nt) Show pHMM detection rules used

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

NRPS/PKS domains

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: oxidoreductase reductase

MK857_RS04550: aldo/keto reductase family oxidoreductase

smcogs: SMCOG1039: aldo/keto reductase family oxidoreductase

MK857_RS04615: hydroxymethylglutaryl-CoA reductase

smcogs: SMCOG1187: hydroxymethylglutaryl-CoA reductase

Ligases: synthase

MK857_RS04620: hydroxymethylglutaryl-CoA synthase

smcogs: SMCOG1043: hydroxymethylglutaryl-CoA synthase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002561.3	0.45	other (other)	phenazine SA, phenazine SB, phenazine SC	Streptomyces sp.
BGC0002508.2	0.45	other (other)	8-azaguanine	Streptomyces pathocidini
BGC0001080.5	0.41	other (phenazine)	endophenazine A, endophenazine B	Streptomyces anulatus
BGC0002707.2	0.41	terpene	(+)-δ-cadinol	Coniophora puteana RWD-64-598 SS2
BGC0000513.3	0.41	ribosomal	Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3	Saccharopolyspora erythraea NRRL 2338
BGC0000515.4	0.41	ribosomal	geobacillin I	Geobacillus thermodenitrificans NG80-2
BGC0001937.4	0.41	other (other)	tubercidin	Streptomyces tubercidicus
BGC0000286.3	0.40	PKS	viguiepinol	Streptomyces sp. KO-3988
BGC0000255.5	0.40	PKS	pederin	Uncultured bacterium
BGC0001210.5	0.40	ribosomal	pseudomycoicidin	Bacillus pseudomycoides DSM 12442

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002561.3	0.45	other (other)	phenazine SA, phenazine SB, phenazine SC	Streptomyces sp.
BGC0002508.2	0.45	other (other)	8-azaguanine	Streptomyces pathocidini
BGC0001080.5	0.41	other (phenazine)	endophenazine A, endophenazine B	Streptomyces anulatus
BGC0002707.2	0.41	terpene	(+)-δ-cadinol	Coniophora puteana RWD-64-598 SS2
BGC0000513.3	0.41	ribosomal	Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3	Saccharopolyspora erythraea NRRL 2338
BGC0000515.4	0.41	ribosomal	geobacillin I	Geobacillus thermodenitrificans NG80-2
BGC0001937.4	0.41	other (other)	tubercidin	Streptomyces tubercidicus
BGC0000286.3	0.40	PKS	viguiepinol	Streptomyces sp. KO-3988
BGC0000255.5	0.40	PKS	pederin	Uncultured bacterium
BGC0001210.5	0.40	ribosomal	pseudomycoicidin	Bacillus pseudomycoides DSM 12442

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

CatR

Description: H2O2-responsive repressor
Species: Streptomyces coelicolor
Score: 22.47 out of 25.31

Confidence: strong

ColR

Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 22.93 out of 30.25

Confidence: medium

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 23.19 out of 26.06

Confidence: medium

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 23.73 out of 26.06

Confidence: medium

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 24.54 out of 27.78

Confidence: strong

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 23.78 out of 27.78

Confidence: medium

SypG

Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 22.82 out of 29.25

Confidence: medium

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 23.95 out of 26.06

Confidence: medium

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 23.52 out of 26.06

Confidence: medium

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 23.06 out of 26.06

Confidence: medium

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 21.70 out of 28.19

Confidence: medium

AfsR

Description: Pleiotropic regulatory for antibiotic production
Species: Streptomyces coelicolor
Score: 19.59 out of 23.05

Confidence: medium

Additional weak hits (4):

RutR

Description: Regulator of the pyrimidine and purine metabolism
Species: Escherichia coli str. K-12 substr. MG1655
Score: 20.55 out of 26.85

Confidence: weak

NtrC

Description: Nitrogen regulatory protein C
Species: Pseudomonas putida KT2440
Score: 20.57 out of 29.72

Confidence: weak

ClgR

Description: Caseinolytic protease gene regulator
Species: Corynebacterium glutamicum ATCC 13032
Score: 20.96 out of 30.22

Confidence: weak

LexA variant 1

Description: Repressor of DNA damage response
Species: Streptomyces coelicolor
Score: 21.44 out of 29.65

Confidence: weak

Detailed domain annotation

Selected features only

Show module domains

TFBS Finder

TFBS definitions

Regulator	Description
AfsR	Pleiotropic regulatory for antibiotic production
CatR	H2O2-responsive repressor
CodY	Regulator of stationary phase and virulence in Gram-positive bacteria
ColR	Phenol-responsive regulator
MogR	Repressor of flagellar motility genes
SypG	Regulator of biofilm formation and host colonization
ZuR variant 1	Zinc-responsive repressor

NZ_JAKVIE010000017.1 - Region 1 - lanthipeptide-class-i

Download region GenBank file

Download region SVG

Location: 1 - 22,542 nt. (total: 22,542 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-i: (((Lant_dehydr_N or Lant_dehydr_C) and cds(LANC_like and not Pkinase)) and not (YcaO or TIGR03604))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Lanthipeptides

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Transferases: phosphotransferase

MK857_RS08390: Glucose-specific phosphotransferase enzyme IIA

smcogs: SMCOG1145: Glucose-specific phosphotransferase enzyme IIA

Hydrolases: protease

MK857_RS08310: alkaline serine protease, subtilase family

smcogs: SMCOG1075: alkaline serine protease, subtilase family

Lyases: cyclase dehydratase

MK857_RS08345: Lantibiotic dehydratase domain protein

smcogs: SMCOG1155: Lantibiotic dehydratase domain protein

MK857_RS08355: Lanthionine synthetase C family protein

smcogs: SMCOG1140: Lanthionine synthetase C family protein

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001789.3	0.98	ribosomal	suicin 90-1330	Streptococcus suis
BGC0000537.3	0.87	ribosomal	nisin U	Streptococcus uberis
BGC0000535.4	0.78	ribosomal	nisin A	Lactococcus lactis subsp. lactis
BGC0000536.3	0.78	ribosomal	nisin Q	Lactococcus lactis
BGC0000538.3	0.75	ribosomal	nisin Z	Lactococcus lactis
BGC0000549.3	0.59	ribosomal	salivaricin D	Streptococcus salivarius
BGC0000506.4	0.59	ribosomal	entianin	Bacillus subtilis subsp. spizizenii
BGC0000559.4	0.57	ribosomal	subtilin	Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0000556.5	0.55	ribosomal	streptin	Streptococcus pyogenes
BGC0001618.3	0.54	ribosomal	hyicin 3682	Staphylococcus hyicus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001789.3	0.98	ribosomal	suicin 90-1330	Streptococcus suis
BGC0000537.3	0.87	ribosomal	nisin U	Streptococcus uberis
BGC0000535.4	0.78	ribosomal	nisin A	Lactococcus lactis subsp. lactis
BGC0000536.3	0.78	ribosomal	nisin Q	Lactococcus lactis
BGC0000538.3	0.75	ribosomal	nisin Z	Lactococcus lactis
BGC0000549.3	0.59	ribosomal	salivaricin D	Streptococcus salivarius
BGC0000506.4	0.59	ribosomal	entianin	Bacillus subtilis subsp. spizizenii
BGC0000559.4	0.57	ribosomal	subtilin	Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0000556.5	0.55	ribosomal	streptin	Streptococcus pyogenes
BGC0001618.3	0.54	ribosomal	hyicin 3682	Staphylococcus hyicus

Similar known clusters from MIBiG 4.0

Similar subclusters

No significant matches found.

Lanthipeptide predictions

Lanthipeptide(s) for MK857_RS08345

MK857_RS08340

Leader:

MNNEDFNLDLVTISKENNSGASPR

Core:

VTSKSLCTPGCKTGILMTCAIKTATCGCHFG

Core with dehydrations:

VDhbDhaKDhaLCysDhbPGCysKDhbGILMDhbCysAIKDhbADhbCysGCysHFG

antiSMASH-DB 4.0 matches for MK857_RS08340

100.0%

NC_015600.1and 14 others:

NZ_AP020310.1 Lanthipeptides: SAGCMC97051_RS07300_lanthipeptideNZ_ATVP01000001.1 Lanthipeptides: G574_RS11150_lanthipeptideNZ_BCFB01000042.1 Lanthipeptides: GOZ36_RS07980_lanthipeptideNZ_CP068708.1 Lanthipeptides: JM964_RS04040_lanthipeptideNZ_CP116958.1 Lanthipeptides: M0P28_RS07755_lanthipeptideNZ_CP116958.1 Lanthipeptides: M0P28_RS07755_lanthipeptideNZ_FIKS01000005.1 Lanthipeptides: A0525_RS10015_lanthipeptideNZ_GL636070.1 Lanthipeptides: HMPREF9171_RS106200_lanthipeptideNZ_JADPLU010000018.1 Lanthipeptides: I4V82_RS09545_lanthipeptideNZ_JAKVIE010000017.1 Lanthipeptides: MK857_RS08340_lanthipeptideNZ_JAQDQV010000001.1 Lanthipeptides: PGO74_RS00635_lanthipeptideNZ_JAQDQV010000001.1 Lanthipeptides: PGO74_RS00635_lanthipeptideNZ_LR594050.1 Lanthipeptides: FGL20_RS03485_lanthipeptideNZ_SSXN01000004.1 Lanthipeptides: FAJ36_RS04715_lanthipeptide

Lanthipeptides: SGPB_RS10680_lanthipeptide

VTSKSLCTPGCKTGILMTCAIKTATCGCHFG

96.9%

NZ_JAMDIB010000004.1:

Lanthipeptides: M5P35_RS04030_lanthipeptide

VTSKSLCTP-GCKTGILMTCAIKTATCGCHFG

VTSKSLCTP GCKTGILMTCAIKTATCGCHFG

VTSKSLCTPPGCKTGILMTCAIKTATCGCHFG

93.5%

NZ_CP024974.1and 1 other:

NZ_JAIMDQ010000006.1 Lanthipeptides: K6V44_RS04045_lanthipeptide

Lanthipeptides: CVO91_RS06555_lanthipeptide

VTSKSLCTPGCKTGILMTCAIKTATCGCHF

VTS SLCTPGCKTGILMTCAIKTATCGCHF

VTSISLCTPGCKTGILMTCAIKTATCGCHF

with 99 more sequence matches

Only the first 10 are displayed here.

87.5%

NZ_CP059471.1and 3 others:

NZ_FNZW01000001.1 Lanthipeptides: BMZ61_RS02110_lanthipeptideNZ_FOYC01000001.1 Lanthipeptides: BMZ88_RS03370_lanthipeptideNZ_KE384124.1 Lanthipeptides: G597_RS0106700_lanthipeptide

Lanthipeptides: H1R75_RS06635_lanthipeptide

VTSKSLCTPGCKTGILMTCAIKTATCGCHFG

+TSKSLCTPGCKTG LMTC IKTATCGCHFG

ITSKSLCTPGCKTGALMTCPIKTATCGCHFG

77.8%

NZ_NHVL01000013.1and 1 other:

NZ_NHVL01000013.1 Lanthipeptides: CEU70_RS16830_lanthipeptide

Lanthipeptides: CEU70_RS16825_lanthipeptide

VTSKSLCTPGCKTGILMTCAIKTATCGC--HFG

VTSKSLCTPGCKTGIL TCAIK+ATCGC H G

VTSKSLCTPGCKTGILQTCAIKSATCGCSIHIG

69.7%

NZ_CP015405.2and 7 others:

NZ_CP015405.2 Lanthipeptides: A4V09_RS08295_lanthipeptideNZ_CP015405.2 Lanthipeptides: A4V09_RS08290_lanthipeptideNZ_CP015405.2 Lanthipeptides: A4V09_RS08285_lanthipeptideNZ_CP053228.1 Lanthipeptides: HL650_RS06240_lanthipeptideNZ_CP053228.1 Lanthipeptides: HL650_RS06235_lanthipeptideNZ_CP053228.1 Lanthipeptides: HL650_RS06230_lanthipeptideNZ_CP053228.1 Lanthipeptides: HL650_RS06225_lanthipeptide

Lanthipeptides: A4V09_RS08300_lanthipeptide

VTSKSLCTPGCKTGILMTCAIKTATCGCHF

+TSKSLCTPGC TGILMTC ++TATCGC

ITSKSLCTPGCVTGILMTCPVQTATCGCQI

69.7%

NZ_JADNJR010000016.1and 2 others:

NZ_JADNJR010000016.1 Lanthipeptides: I2E58_RS10875_lanthipeptideNZ_QSHK01000002.1 Lanthipeptides: DW860_RS04740_lanthipeptide

Lanthipeptides: I2E58_RS10880_lanthipeptide

SKSLCTPGCKTGILMTCAIKTATCGCHF

SKS CTPGC TGILMTC +KTATCGCH

SKSACTPGCPTGILMTCPLKTATCGCHI

69.7%

NZ_QSHK01000002.1and 1 other:

NZ_QSHK01000002.1 Lanthipeptides: DW860_RS04730_lanthipeptide

Lanthipeptides: DW860_RS04735_lanthipeptide

SKSLCTPGCKTGILMTCAIKTATCGCHF

SKS+CTPGC TGILMTC +KTATCGCH

SKSVCTPGCPTGILMTCPLKTATCGCHI

66.7%

NZ_FNDP01000013.1and 1 other:

NZ_FNDP01000013.1 Lanthipeptides: BLP54_RS11220_lanthipeptide

Lanthipeptides: BLP54_RS11225_lanthipeptide

VTSKSLCTPGCKTGILMTCAIKTATCGC--HFG

+TSKSLCTPGC TG+LM CA +ATC C H G

ITSKSLCTPGCVTGLLMGCAGSSATCNCSVHVG

65.7%

NZ_FNDP01000013.1:

Lanthipeptides: BLP54_RS11230_lanthipeptide

VTSKSLCTPGCKTGILMTCAIKTATCGC--HFG

+TSKSLCTPGC TG+LM C KTATC C H G

ITSKSLCTPGCVTGVLMGCNNKTATCNCSVHVG

64.7%

NZ_CP090412.1and 3 others:

NZ_QSTB01000004.1 Lanthipeptides: DXC22_RS03785_lanthipeptideNZ_VSTZ01000009.1 Lanthipeptides: FYK98_RS07445_lanthipeptideNZ_VSTZ01000009.1 Lanthipeptides: FYK98_RS07445_lanthipeptide

Lanthipeptides: LZF92_RS09890_lanthipeptide

VTSKSLCTPGCKTGILMTCAIKTATCGCHF

+TS SLCTPGCKTG LM C +KTA+CGCH

ITSYSLCTPGCKTGALMGCTMKTASCGCHV

64.7%

NZ_FBTD01000003.1:

Lanthipeptides: PB1E_RS03075_lanthipeptide

VTSKSLCTPGCKTGILMTCAIKTATCGCHF

+TS SLCTPGCKTG LM C +KTA+CGCH

ITSVSLCTPGCKTGALMGCNMKTASCGCHV

62.9%

NZ_CP013655.1and 2 others:

NZ_CP013655.1 Lanthipeptides: ATZ35_RS03635_lanthipeptideNZ_CP013655.1 Lanthipeptides: ATZ35_RS03630_lanthipeptide

Lanthipeptides: ATZ35_RS03640_lanthipeptide

VTSKSLCTPGCKTGILMTCAIKTATCGCHFG

+TSKSLCTPGC TG+LM CA+KT TC C G

ITSKSLCTPGCVTGVLMGCALKTITCNCSVG

MIBiG 4.0 matches for MK857_RS08340

61.8%

BGC0000535.4 (ADJ56352.1):

Lanthipeptide: nisin A

VTSKSLCTPGCKTGILMTCAIKTATCGC

+TS SLCTPGCKTG LM C +KTATC C

ITSISLCTPGCKTGALMGCNMKTATCHC

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Transcription Factor Binding Sites

No hits above weak threshold.

Weak hits (2):

ClgR

Description: Caseinolytic protease gene regulator
Species: Corynebacterium glutamicum ATCC 13032
Score: 20.03 out of 30.22

Confidence: weak

HypR

Description: L-hydroxyproline utilization repressor
Species: Streptomyces coelicolor
Score: 18.59 out of 22.40

Confidence: weak

Lanthipeptides

RREFinder

TFBS Finder

Core peptide predictions

MK857_RS08340 - Class I

Cleavage pHMM score: 27.40

RODEO score: 28

Monoisotopic mass: 2987.5 Da

Molecular weight: 2989.6 Da

Number of bridges: 5

Alternative weights: (assuming N unmodified Ser/Thr residues); 3007.6 Da N = 1; 3025.7 Da N = 2; 3043.7 Da N = 3

RRE predictions

: RRE type: Lanthipeptide_LanB_RRE; Location: 144 - 226; Score: 25.6

TFBS definitions

Regulator	Description

NZ_JAKVIE010000005.1 - Region 1 - terpene-precursor

Download region GenBank file

Download region SVG

Location: 98,780 - 119,649 nt. (total: 20,870 nt) Show pHMM detection rules used

terpene-precursor: (PT_FPPS_like and not PT_HPP)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Terpene

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Transferases: carbamoyltransferase

MK857_RS02955: ornithine carbamoyltransferase

smcogs: SMCOG1114: ornithine carbamoyltransferase

Ligases: synthetase

MK857_RS02900: Polyprenyl synthetase

smcogs: SMCOG1182: Polyprenyl synthetase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002397.2	0.47	terpene	astallatene	Arabidopsis thaliana
BGC0002400.2	0.44	terpene	boleracene	Brassica oleracea var. oleracea
BGC0002398.2	0.38	terpene	(-)-ent-quiannulatene	Arabidopsis thaliana
BGC0000542.3	0.37	ribosomal	paenicidin B	Paenibacillus terrae
BGC0000541.5	0.37	ribosomal	paenicidin A	Paenibacillus polymyxa
BGC0000552.3	0.36	ribosomal	SmbA, SmbB	Streptococcus mutans
BGC0000498.5	0.36	ribosomal	bovicin HJ50	Streptococcus equinus
BGC0000561.5	0.35	ribosomal	thermophilin 1277	Streptococcus thermophilus
BGC0002635.2	0.35	ribosomal	daspyromycin A, daspyromycin B	Actinokineospora diospyrosa
BGC0002298.2	0.35	ribosomal	lassomycin-like peptide	Sanguibacter keddieii DSM 10542

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002397.2	0.47	terpene	astallatene	Arabidopsis thaliana
BGC0002400.2	0.44	terpene	boleracene	Brassica oleracea var. oleracea
BGC0002398.2	0.38	terpene	(-)-ent-quiannulatene	Arabidopsis thaliana
BGC0000542.3	0.37	ribosomal	paenicidin B	Paenibacillus terrae
BGC0000541.5	0.37	ribosomal	paenicidin A	Paenibacillus polymyxa
BGC0000552.3	0.36	ribosomal	SmbA, SmbB	Streptococcus mutans
BGC0000498.5	0.36	ribosomal	bovicin HJ50	Streptococcus equinus
BGC0000561.5	0.35	ribosomal	thermophilin 1277	Streptococcus thermophilus
BGC0002635.2	0.35	ribosomal	daspyromycin A, daspyromycin B	Actinokineospora diospyrosa
BGC0002298.2	0.35	ribosomal	lassomycin-like peptide	Sanguibacter keddieii DSM 10542

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Detailed terpene predictions

Product predictions:

Class	Subclass	Product name	Chain length	Initial cyclisations	Functional groups
sesquiterpene precursor		FPP	C15	acyclic	PP

Genes with terpene domains:

MK857_RS02900: PT_FPPS_like

Domain 1 (25 - 273): Prenyltransferase; Farnesyl diphosphate synthase like

Subtype: Farnesyl diphosphate synthase, bacterial

Reactions:: DMAPP, IPP → FPP

Transcription Factor Binding Sites

Binding sites found:

ToxT

Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.57 out of 18.57

Confidence: strong

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 26.74 out of 27.78

Confidence: strong

LuxO

Description: Repressor of luminescence
Species: Vibrio campbellii ATCC BAA-1116
Score: 22.86 out of 26.12

Confidence: medium

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 23.35 out of 26.06

Confidence: medium

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.88 out of 26.06

Confidence: medium

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 23.06 out of 26.06

Confidence: medium

PsrA

Description: Oleic acid responsive regulator
Species: Pseudomonas sp.
Score: 21.38 out of 25.88

Confidence: medium

Additional weak hits (4):

PerR

Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 23.47 out of 28.14

Confidence: weak

PerR

Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 23.54 out of 28.14

Confidence: weak

FuR variant 2

Description: Ferric Uptake Regulator
Species: Caulobacter crescentus CB15
Score: 23.05 out of 32.74

Confidence: weak

NuR

Description: Nickel-responsive regulator
Species: Streptomyces coelicolor
Score: 23.25 out of 30.98

Confidence: weak

Terpene

TFBS Finder

Glossary

Acronym	Full name
DMAPP	Dimethylallyl diphosphate
FPP	Farnesyl diphosphate
IPP	Isopentenyl diphosphate
PP	Diphosphate

TFBS definitions

Regulator	Description
CodY	Regulator of stationary phase and virulence in Gram-positive bacteria
LuxO	Repressor of luminescence
MogR	Repressor of flagellar motility genes
PsrA	Oleic acid responsive regulator
ToxT	Regulator of MSHA biosynthesis