LOCUS       NZ_JAKVIE010000010     41179 bp    DNA     linear   CON 23-JAN-2024
DEFINITION  Streptococcus pasteurianus strain D17293137
            D17293137_S20_contig_10_consensus, whole genome shotgun sequence.
ACCESSION   NZ_JAKVIE010000010
VERSION     NZ_JAKVIE010000010.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptococcus pasteurianus
  ORGANISM  Streptococcus pasteurianus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 286213)
  AUTHORS   Christensen,J., Jensen,C., Dargis,R., Nielsen,X., Pries- Heje,M.,
            Wiingaard,C., Ihlemann,N., Gill,S., Bruun,N., Elming,H., Povlsen,J.,
            Madsen,T., Jensen,K., Fuursted,K., Ostergaard,L., Christiansen,U.,
            Rosenvinge,F., Helweg-Larsen,J., Fosbol,E., Kober,L.,
            Torp-Pedersen,C., Tonder,N., Moser,C., Iversen,K. and Bundgaard,H.
  TITLE     Genomic identification of streptococcal strains and relation to
            clinical characteristics. A substudy to The Partial Oral Treatment
            of Endocarditis (POET) Trial
  JOURNAL   Med Res Arch 10 (9) (2022) In press
  REMARK    DOI: 10.18103/mra.v10i9.3037
REFERENCE   2  (bases 1 to 286213)
  AUTHORS   Christensen,J.J.E., Jensen,C.S., Nielsen,X.C. and Dargis,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2022) Department of Clinical Microbiology, Region
            Zealand, Ingemannsvej 46, Slagelse 4200, Denmark
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.13.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 72.66x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/23/2024 02:09:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,313
            CDSs (total)                      :: 2,260
            Genes (coding)                    :: 2,168
            CDSs (with protein)               :: 2,168
            Genes (RNA)                       :: 53
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 46
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 38 of 92
            Pseudo Genes (incomplete)         :: 58 of 92
            Pseudo Genes (internal stop)      :: 34 of 92
            Pseudo Genes (multiple problems)  :: 30 of 92
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:47:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 8527
            Orig. end                         :: 49706
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAKVIE010000010.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..41179
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T3PKS"
                     /region_number="1"
                     /rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /tool="antismash"
     cand_cluster    1..41179
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /kind="single"
                     /product="T3PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..41179
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:21179](-)"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..21179)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
     misc_feature    24..39
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.55"
                     /tool="antismash"
     misc_feature    complement(137..153)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: weak, score: 20.57"
                     /tool="antismash"
     misc_feature    complement(651..666)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 20.96"
                     /tool="antismash"
     misc_feature    677..690
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: strong, score: 22.47"
                     /tool="antismash"
     gene            764..1216
                     /locus_tag="MK857_RS04510"
                     /old_locus_tag="MK857_04490"
     CDS             764..1216
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854390.1"
                     /locus_tag="MK857_RS04510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04490"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_003065246.1"
                     /transl_table=11
                     /translation="MISNAKKYARLRDEQFSLYESYAKKHGLNSKSLLVFMWIYHNPHG
                     MTQESIAKRTFSTKQVIQAIVKTYMKKGILYLEPSRIDRRKKLIRLTETGQQFAAELLD
                     PLADFEAQAMSALTLEEQEVLLSATAMFTDRLTELLESHQVKEHVK"
     gene            1206..1841
                     /locus_tag="MK857_RS04515"
                     /old_locus_tag="MK857_04495"
     CDS             1206..1841
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294714.1"
                     /locus_tag="MK857_RS04515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04495"
                     /product="ABC transporter permease"
                     /protein_id="WP_003065244.1"
                     /transl_table=11
                     /translation="MLNDIAAYFADNGNTYLGYVWQHISLSFEALVIALIIALPLGYFS
                     YEKPFVRQLSTLLTQGLRVIPSLGILFILIPFIGVGRLPALIALVILGIPPILLNTIVG
                     VASVSENLLETALGLGMTRSQLLTKVQFPLALPHILNGIKLALVEIIASATLATYIGAG
                     GLGTLIFTGLGLYRYDLLLIGGGSVAILSFLSMIIFDLSIKGVEHYEK"
     gene            1831..2751
                     /locus_tag="MK857_RS04520"
                     /old_locus_tag="MK857_04500"
     CDS             1831..2751
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003065242.1"
                     /locus_tag="MK857_RS04520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04500"
                     /product="glycine betaine ABC transporter substrate-binding
                     protein"
                     /protein_id="WP_003065242.1"
                     /transl_table=11
                     /translation="MKNKKVISGALLVVILVAIVGGIWAWRNNQSSEVQQSSTTIRVGS
                     KDFTENLVIAEIYALALEDNGYTVERVSNISSSLIHNSIVNDEIDLYPEYTGTGLLSVL
                     GEDMETDPEKVYKTVKKEYEEQFNLTWLDYASANDSQGLVIRTEVANSLNIKTISDLQA
                     HASELRFASQGEFDEREDGLLGLEKTYGTFNWQSSKVYDNSLKYSVLENDEADVTPAYT
                     TEGQLVSTDKFTLLEDDKQFWPPYNLAPVVRDNILDDNPDIKTILNNISAKLDTETVTE
                     LNAKVDVDGQEYTDVAKEYYDSIKG"
     gene            2779..3537
                     /locus_tag="MK857_RS04525"
                     /old_locus_tag="MK857_04505"
     CDS             2779..3537
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018373513.1"
                     /locus_tag="MK857_RS04525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04505"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_172473475.1"
                     /transl_table=11
                     /translation="MIQFEHVSKVYGDKTVVNDINLTIENGEFITILGTSGSGKTTMLK
                     MINKLIEPTSGTIFFAGQDIEQMDSVSLRRQIGYVVQQIGLFPHMTVAENIATVPKLLG
                     WDKERIENRVGELLDLVQLPAVDYGERYPSELSGGQQQRIGVARALAADPDVMLFDEPF
                     GAIDAITRNDLQEELQAIHQKLSQKTFVFITHDIYEAFKLGTRVVIMDNGTICQFDTPE
                     NIIKNPGNEFVQRLITTAQEQEKLWRASYD"
     gene            3530..4156
                     /locus_tag="MK857_RS04530"
                     /old_locus_tag="MK857_04510"
     CDS             3530..4156
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003065238.1"
                     /locus_tag="MK857_RS04530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04510"
                     /product="ABC transporter permease"
                     /protein_id="WP_003065238.1"
                     /transl_table=11
                     /translation="MIDYFKTSSDKLITALIEHIELTSFSLLFALLFASVITVILLFYP
                     KIRLASVYVLSLLYAIPSFALFTLLIPVTGLGTRTAIIVLVIYAQYTLVRTFLAGLTQV
                     DDSIVEAATGMGMTRWQILAKIQLPLAQSSIFAGLRLAASSMIAIATIASTINAGGLGS
                     ILFDGLRTMSLPKLLWGIILTVALSLLVNLILYLVEELVKNESVS"
     gene            4292..4915
                     /locus_tag="MK857_RS04535"
                     /old_locus_tag="MK857_04515"
     CDS             4292..4915
                     /GO_process="GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003065236.1"
                     /locus_tag="MK857_RS04535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04515"
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="WP_003065236.1"
                     /transl_table=11
                     /translation="MTDMIYGEYADYLPLILEDFSQRIRKKNDEVKKETGYKLFEHFIA
                     RVKTPESMTEKCQRKNLPVTTESALKKVRDSIGLRIICGFVDDIYTLVDLIRSFDDCTI
                     VAEKDYIKNAKPNGYRSYHLIVEVVTPYPDCLGNRQGSYFIEIQLRTIAMDSWASLEHQ
                     MKYKHDIKDPKRIVRELKRCADELASCDLTMQTIRNLIQESSQD"
     gene            4945..5625
                     /locus_tag="MK857_RS04540"
                     /old_locus_tag="MK857_04520"
     CDS             4945..5625
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013643180.1"
                     /locus_tag="MK857_RS04540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04520"
                     /product="response regulator transcription factor"
                     /protein_id="WP_003065234.1"
                     /transl_table=11
                     /translation="MKILVAEDEIQMNRVLTTALTHEGYDVDSVYDGQAAIDMATENAY
                     DVMVMDIMMPVKSGIEAVQEIRQTGNQSHIIMLTAMAEVDDRVTGLDAGADDYLTKPFS
                     LKELLARLRSMSRRVDTNFTSNILTVGTVTLNVGEQELVSQNTIRLAGKESKMLEFFML
                     NAGKKLSTDQIFNHVWANDKDDPEIDNGYVFIYVSYLRQKLKSIGANVVIEGEEMGGYE
                     LKEL"
     misc_feature    complement(4962..4976)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.7"
                     /tool="antismash"
     gene            5634..6863
                     /locus_tag="MK857_RS04545"
                     /old_locus_tag="MK857_04525"
     CDS             5634..6863
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489520.1"
                     /locus_tag="MK857_RS04545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04525"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_003065232.1"
                     /transl_table=11
                     /translation="MFRKLRLRFIAITSLAILIVLFSVVGVLNSARHIQKVNEINKILT
                     LISDNGGTFPSVSKVTSELGDTVSVDTLFQYRYFSAVVDKDGNITSLNLSSISDLTNEQ
                     VENYLIKINKSGDTRGDFRYSNHTYSYLVTDESDDSTLIVVLDSTNQVEENMTLVHLSL
                     WMSGVSFAFFVLMVSIFSGRVIEPFIRNYERQRRFITNAGHELKTPLAIISANNELVEM
                     MNGESEWTKSTNDQVERMTGLINSLVAMARLEEQPEVVLTDLNFSAIAEDAAEDFKGPV
                     IKDGKQFIMEIQPDIHVKAEEKSLFELVTLLVDNANKYCDAGGTVSVKLSKANRLSKAR
                     LEISNTYVEGKNVDYSKFFERFYREDESHNNKKSGYGIGLSMAQTMVKLFKGSISVSYS
                     GDTITFLVSL"
     gene            complement(7015..7854)
                     /locus_tag="MK857_RS04550"
                     /old_locus_tag="MK857_04530"
     CDS             complement(7015..7854)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003065230.1"
                     /locus_tag="MK857_RS04550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04530"
                     /product="aldo/keto reductase"
                     /protein_id="WP_003065230.1"
                     /transl_table=11
                     /translation="MNFKTLNNGIQIPVLGFGVWQIFDQAQCQESVENALEVGYRLIDT
                     AAIYKNEEAVGRAMKASSLSREDVFLTSKVWIDHLGYTETKKAFEETLRKLDTDYLDLY
                     LIHQPYGDTHGAWRAMIELYKEGYIRAIGVSNFSTGRLTDFALNTEVVPALNQIELHPY
                     KQHPIIQAANAQFGIATQAWSPFNRGEDNIFRDATLNSIAEKHGKTVAQVILRWQVQND
                     ILTIPKSVHLERMKENFDIFDFELTPDDIKQIQALDRFPNNYGPNESPEHVQRLLGL"
     gene            complement(7921..8814)
                     /locus_tag="MK857_RS04555"
                     /old_locus_tag="MK857_04535"
     CDS             complement(7921..8814)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013851956.1"
                     /locus_tag="MK857_RS04555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04535"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_101774244.1"
                     /transl_table=11
                     /translation="MNFQQCRYVEAVARVGSFSQAAKELFMTQPNLSSSIKDLENELGV
                     QLFTRSNTTEDGYDFLKYAKRIIGELDLLEQRYHDQFKKSFTVASHHYDFLSIPLAKVA
                     QEFNQDYQEFQTIETTTKKILESVARFEADLGIIYLDDENKHILESSLEHHDLEFTSLG
                     DFPTRVFLRRNHPLAHKDVISESDLKGYDQIRFRQEQSGLNFDEDALQIHNTQHVLYSN
                     DRGTVMNLLCATDAYASGLGIVNSFVRNQIVLIPLQDSPKHTLGYVTNKKKKVSKIGTA
                     FIQEIKKSLNDFPEAN"
     gene            9391..10395
                     /locus_tag="MK857_RS04560"
                     /old_locus_tag="MK857_04540"
     CDS             9391..10395
                     /GO_function="GO:0004853 - uroporphyrinogen decarboxylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323598.1"
                     /locus_tag="MK857_RS04560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04540"
                     /product="uroporphyrinogen decarboxylase family protein"
                     /protein_id="WP_172473474.1"
                     /transl_table=11
                     /translation="MMTTKREWVLKAFKNEKVDKVPVGFWYHFTTDDERGDGFNPEIFN
                     KNIAGHKKFVLDVNPDFVKVMSDGFFTYPNEQIHQGVTSIKELEGIVSIGENHPWITQQ
                     VELAKKIREDFPEDIASFYNIFAPVTYLKWQLAGKGGNGDEIIENFIKEDAELTKEVLD
                     VVAGDIGILTKRLIKEAGVDGIYLSVQNLQDSRSSKEEYNQVIKPGELHILNRAISAGG
                     TNILHICGYEGATNDIMYYTDYPADVINWAVELEGVSLSEGRQLFGGKTVLGGFENTEK
                     GLLYLGSKEAIQGKVKELLDEAGRQGVVIGADCTVPSDISSKRIDWVKEAVAL"
     gene            10422..11300
                     /locus_tag="MK857_RS04565"
                     /old_locus_tag="MK857_04545"
     CDS             10422..11300
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004232081.1"
                     /locus_tag="MK857_RS04565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04545"
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="WP_041973602.1"
                     /transl_table=11
                     /translation="MSKKKWIVAGGIVVALVAATVIGRQLTGKTTASAQSSSGDSDKVT
                     TLQVAHTQNYVPYDYVDENGESDGFEVAVLKAVDKKLKNYKFEYTGTSDEDLLIGLESG
                     KYDIGVKGAWYTAERAEKFVIPDEAIGASVIGFAIRKEDESKYTDIDSFANSGGKLVPI
                     SPQNAQYNVIQEYNKTAKNPIELIESESFSVADAYAWVLEGRYDAYFSIKLSFEEAVQD
                     EDGAYHQYADQLTWFPYKGIETYPLIHKNATNEAFAEEYDKAIKGLKEDGTIAKLSEKY
                     FGEDVFSYVTD"
     gene            11310..12002
                     /locus_tag="MK857_RS04570"
                     /old_locus_tag="MK857_04550"
     CDS             11310..12002
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003065219.1"
                     /locus_tag="MK857_RS04570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04550"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_003065219.1"
                     /transl_table=11
                     /translation="MVSYEPSRVITFLPEILSALPLTLWVLVLTILFGSLLGLFLAWSQ
                     LSGEKSLPSFARGYVFILRCTPPIVLIFLVFYGLPRFLEWWLGIDVNGWSRSVFVILAM
                     TLLFAASISEVFKSSYQALPKGQLEAGLSIGLTDYQTFVRILLPQAFRIALPNITTAII
                     NLLKDIALAYTIGLVDLMGAGNLVISRNLGNYSLETYTAVAIIYWVLALILAVGTHFIE
                     NELDTTRG"
     gene            12012..12692
                     /locus_tag="MK857_RS04575"
                     /old_locus_tag="MK857_04555"
     CDS             12012..12692
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003065217.1"
                     /locus_tag="MK857_RS04575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04555"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_048791474.1"
                     /transl_table=11
                     /translation="MDFSYILETFVKILSGIPVTLGIMVVSILLSFFPALFLALGRIYK
                     VKGVTGFSVIYLAFIRSTPAILLILFFYSLFPSLINQLLKATGFNIFDINPIYYAYIIF
                     GLMTTGSLSEIIRSAILTVDKGQLEAAQAIGLSTSQAYIRIVFPQAIRQALPNLCNLVI
                     NLVKGTSLVFVMTVKDITAIAKIEAAYGYHYFESYFVIFIIYIVICGLIQYGFKFLEKR
                     AQIV"
     gene            12713..13471
                     /locus_tag="MK857_RS04580"
                     /old_locus_tag="MK857_04560"
     CDS             12713..13471
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803323.1"
                     /locus_tag="MK857_RS04580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04560"
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_009854375.1"
                     /transl_table=11
                     /translation="MLSVKNIEKSFGDKKVLDGISLTVNQGDVVVILGPSGSGKTTFLR
                     SLNYLEKADAGELILDGKTYDLAKISRKDVLEIRKKTAFVFQNYNLFANKTAIENILEG
                     LVIARKIPKEEAIPIAENALKKVGLLEKKDYYPSQLSGGQQQRIGIARAIAVKPDVILF
                     DEPTSALDPELIGDVLDVMKELAQEGVTMVVVTHEMSFARDVATHVIFMEGGHIIEEGD
                     PKEFFSKPKEERTKQFLTRIIPELNIDPVI"
     gene            13594..14472
                     /gene="mvk"
                     /locus_tag="MK857_RS04585"
                     /old_locus_tag="MK857_04565"
     CDS             13594..14472
                     /EC_number="2.7.1.36"
                     /GO_function="GO:0004496 - mevalonate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016126 - sterol biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /gene="mvk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004232073.1"
                     /locus_tag="MK857_RS04585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04565"
                     /product="mevalonate kinase"
                     /protein_id="WP_003065213.1"
                     /transl_table=11
                     /translation="MTKKIGVGKAHSKIIWMGEHSVVYGYPAIAIPLQGIKVECHIYPA
                     EEKIHFDFYDTLSTAVYAALEYLNHTDVSITYAIRSEIPQKRGMGSSAAVSIAAIRAVF
                     DYFEQSIDMNTLEILVNKAEIIAHSNPSGLDAKTCLSDKAITFIRNIGFSTLDLDLDAY
                     LVIADTGIYGNTREAVEKVAQAEEANLPHLAALGDLTEIVQKAIQDKDIQKIGHMMTKA
                     HAHLQAIGVSIDVSDQLVKLSLGNGALGAKMSGGGLGGCIIALASTKADAEKISNALKE
                     GGAVQTWIEKL"
     gene            14454..15404
                     /gene="mvaD"
                     /locus_tag="MK857_RS04590"
                     /old_locus_tag="MK857_04570"
     CDS             14454..15404
                     /EC_number="4.1.1.33"
                     /GO_function="GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /gene="mvaD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004232072.1"
                     /locus_tag="MK857_RS04590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04570"
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="WP_048791473.1"
                     /transl_table=11
                     /translation="MDRKIVTVKSYANIAIIKYWGKADAIKMIPATSSISLTLENMFTT
                     TTVSFLPQSVGHDEFYINGVLQDEKEHAKISAIIDQYRGGRSEFVKVETSNNMPTAAGL
                     SSSSSGLSALVKACNELFETGLNQSELAQKAKFASGSSSRSFFGPIAAWDKDSGDIYPV
                     QTNLKLAMIMLVLSDSKKPISSREGMKRCAETSTTFADWVKQSEQDYKDMLAYLEANDF
                     EKVGELTERNALAMHDTNTHANPPFNYLTNETYAAMDFVKSLRAQGEKCYFTMDAGPNV
                     KVLCLEEDLERLTKRFEENYRVIASRTKVLPDEND"
     gene            15391..16398
                     /locus_tag="MK857_RS04595"
                     /old_locus_tag="MK857_04575"
     CDS             15391..16398
                     /EC_number="2.7.4.2"
                     /GO_function="GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016126 - sterol biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003065208.1"
                     /locus_tag="MK857_RS04595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04575"
                     /product="phosphomevalonate kinase"
                     /protein_id="WP_048791472.1"
                     /transl_table=11
                     /translation="MKTISVQTGGKLYIAGEYAILTPGQTAILKNIPIPMTAIVKEAKK
                     ISLFSDMFDYATDMTVDKNYTLIQQTIVTLATYLDKSLHDLPAFKLDITGKLERDGKKF
                     GIGSSGSVTVLTLKALSAFYELKLSADTIFKLASYTLLKLGDNGSMGDIACIAYDDLVA
                     FTSFDRQKVSTWIATEDIKTVLAKDWGYRIEIIKPALLCDFLVGWTKQPSISKDMINLV
                     KSAITRAFLEDTERNVQFCKQALQTGNKMAVKASLQKVSDLLLGLSSAIYNDKLKALKS
                     AEKGLDVIAKSSGSGGGDCGIAISFSESDSHELAQRWQKAGIEILYQERLSDER"
     gene            16440..17438
                     /gene="fni"
                     /locus_tag="MK857_RS04600"
                     /old_locus_tag="MK857_04580"
     CDS             16440..17438
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fni"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013643168.1"
                     /locus_tag="MK857_RS04600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04580"
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_003065206.1"
                     /transl_table=11
                     /translation="MINRKDEHIKYALKYQSPYNSFDDIELIHHSLPDYDLSEIDLHTH
                     FAGRDFEFPFYINAMTGGSEKGRAVNQKLAQIAQATGLVMVTGSYSAALKNPHDDSYPS
                     KEEFPELLLATNIGIDKPYELGLQTIHEMQPIFLQVHVNLMQELLMPEGEREFRQWKEN
                     LADYATKMPAPVILKEVGFGMDLKTIEMAHKLGIKTVDISGRGGTSFAYIENQRGHNRS
                     YLDEWGQSTVQTLLNAQPMIDKIEILASGGVRHPLDIIKCLVLGAKAVGVSRAILELVE
                     KYSVEEVITIINGWKDDLRLIMCALNCKTIAELRQVDYLLYGKLNEANQKR"
     gene            complement(17478..18134)
                     /locus_tag="MK857_RS04605"
                     /old_locus_tag="MK857_04585"
     CDS             complement(17478..18134)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286719.1"
                     /locus_tag="MK857_RS04605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04585"
                     /product="hemolysin III family protein"
                     /protein_id="WP_048791471.1"
                     /transl_table=11
                     /translation="MNASMTMKLSKRLSFGEEVANSVTHAVGAVAMLVLLPITAIYSYH
                     HYGIEAAVGMSIFDISLFLMFLSSTIYHSMQYDSPQKFILRIIDHSMIYIAIAGSYTPV
                     ALSLVGGWLGYVIIILQWGATIFGILYKIFAKKINERFSLFLYLLMGWLVIFIIPSIVS
                     KTGVAFWLLMLAGGLSYTIGAIFYARKRPYDHMIWHLFILLASVLHYIAIVYYML"
     gene            complement(18124..18567)
                     /locus_tag="MK857_RS04610"
                     /old_locus_tag="MK857_04590"
     CDS             complement(18124..18567)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003065202.1"
                     /locus_tag="MK857_RS04610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04590"
                     /product="DUF1836 domain-containing protein"
                     /protein_id="WP_003065202.1"
                     /transl_table=11
                     /translation="MTMSYPKWSELPDIDLYLDQVLLYVNQIGEANHQNEKGLTASMIN
                     NYVKHGHLEKPIKKKYSRKQVARLIVITSLKNVFSIQEISQTLAILTADNQSQKRYDDF
                     VACMNGEKIDDLPPVVVSACQTLQLYYQTHQLVQELEGEKDEC"
     misc_feature    complement(18663..18678)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 22.93"
                     /tool="antismash"
     misc_feature    complement(18692..18703)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.59"
                     /tool="antismash"
     gene            complement(18743..20026)
                     /locus_tag="MK857_RS04615"
                     /old_locus_tag="MK857_04595"
     CDS             complement(18743..20026)
                     /EC_number="1.1.1.88"
                     /GO_function="GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA]"
                     /GO_process="GO:0016054 - organic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1187: hydroxymethylglutaryl-CoA reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854364.1"
                     /locus_tag="MK857_RS04615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04595"
                     /product="hydroxymethylglutaryl-CoA reductase, degradative"
                     /protein_id="WP_048791470.1"
                     /transl_table=11
                     /translation="MEKQTKSTKVNWSGFSKKAITERLEHLENNRLLSTETLNDLKENT
                     LLSLETANQLTENVLGTFSLPFSVAPDFQVDGATFNVPMVTEEPSVVAAASFAAKIIKR
                     SGGFKTKVHSRKMIGQVALYDVVDKAIAKETILNHSAQLLTLANEAHPSIVKRGGGARE
                     LTVEEKDEFLIVYLTVDTQEAMGANMVNTMMEALVPSLEELSGGKSLMAILSNYATQAL
                     VTTECQVDLRYLSRNKTEAQALASKFQLASKLAQVDVYRATTHNKGIFNGIDAVVLATG
                     NDWRAIEAGANAYACKDGQCRGLATWSFDKEQQVLRGQLTLPMPIATRGGSIGLNPTVK
                     IAHELLGHPDAQTLAKIIVSVGLAQNFAAVKALTSTGIQAGHMKLQAKSLALLAGATEN
                     EVGKVVQQLLQAPHMNLETAKTILNNLK"
     gene            complement(20001..21179)
                     /locus_tag="MK857_RS04620"
                     /old_locus_tag="MK857_04600"
     CDS             complement(20001..21179)
                     /EC_number="2.3.3.10"
                     /GO_function="GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043: hydroxymethylglutaryl-CoA synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003065199.1"
                     /locus_tag="MK857_RS04620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04600"
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="WP_048791469.1"
                     /sec_met_domain="Chal_sti_synt_N (E-value: 5.6e-07,
                     bitscore: 23.4, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIGIDKIGFATSQYMLNMDDLAESRQVDPEKYSKGLLLRTLSIA
                     PVNDDIVTLGASAADSILTNDDKEAIDMVIVATESSVDQSKAAATCIHNLLGIQPFARS
                     IEMKEACYSATAALDYARLHVEKHPESKVLVIASDIARYGAHTSGEPTQGAGSIAMLIS
                     QDPQILLLNDNFVAQTRDIMDFWRPNYSTTPYVNGIYSTKQYLDMLKTTWAEFQKRFNT
                     SLSDFSAFCFHLPFPKLALKGFNKIMDKTLPADLQEKLKANFESSILYSKQVGNIYTGS
                     LFLGLLSLLENSENLVGGDNIAFFSYGSGAVAEIFTGTLVEGFKDKLKNSRLQELKQRI
                     ALSVEDYERIFFEEPVLDADGNASFANYKTGTFALKEIRGHERIYGKTNEID"
     misc_feature    complement(21460..21473)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.19"
                     /tool="antismash"
     gene            21499..22338
                     /locus_tag="MK857_RS04625"
                     /old_locus_tag="MK857_04605"
     CDS             21499..22338
                     /EC_number="2.1.1.45"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /locus_tag="MK857_RS04625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04605"
                     /product="thymidylate synthase"
                     /protein_id="WP_048791468.1"
                     /transl_table=11
                     /translation="MTKADVIFKENIKKIMEEGVFSENARPVYQSGGQANSKYVTGAFA
                     EYDLSKGEFPITTLRPIPIKSAIREIFWIYQDQTNDLSVLNDKYNVKYWNDWEVDNSGT
                     IGERYGAVVKKHDIIRKILKQLEENPWNRRNVISLWDYEAFENTDGLLPCAFQTMYDVR
                     RVDGEIYLDATLTQRSNDMLVSHHINAMQYVALQMMIAKHFGWKVGKFFYFVNNLHIYD
                     NQFEQARELLSRESTDCKPRLVLNVPDGTDFFDIKPEDFELVDYEPVKPQIKFDLAI"
     misc_feature    21517..21530
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.73"
                     /tool="antismash"
     gene            22426..22920
                     /locus_tag="MK857_RS04630"
                     /old_locus_tag="MK857_04610"
     CDS             22426..22920
                     /EC_number="1.5.1.3"
                     /GO_function="GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166044.1"
                     /locus_tag="MK857_RS04630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04610"
                     /product="dihydrofolate reductase"
                     /protein_id="WP_048791467.1"
                     /transl_table=11
                     /translation="MTKKIVAIWAEDENRLIGVNDGLPWRLPKELKHFKETTMGQALLM
                     GRVTFDGMNRRILPGRETLILTRDKSFEADGVRIVHDMDEVFDWFKKQDKTLYIVGGAS
                     IYKAFLPHCDAIIKTTVHGVFEGDTYFPDIDLTSFRKVSETFNEKDDKNAYDFTITVLE
                     K"
     gene            22936..23106
                     /locus_tag="MK857_RS04635"
                     /old_locus_tag="MK857_04615"
     CDS             22936..23106
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302775.1"
                     /locus_tag="MK857_RS04635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04615"
                     /product="hypothetical protein"
                     /protein_id="WP_003065196.1"
                     /transl_table=11
                     /translation="MQRSIFGVFTAFLAVICILCALPALRKKRYGLAVLLFLNAFTNIV
                     NTIHAVYGTLF"
     gene            23139..24368
                     /gene="clpX"
                     /locus_tag="MK857_RS04640"
                     /old_locus_tag="MK857_04620"
     CDS             23139..24368
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="clpX"
                     /gene_functions="other (smcogs) SMCOG1223: ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /locus_tag="MK857_RS04640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04620"
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="WP_003065195.1"
                     /transl_table=11
                     /translation="MVGNRTNDVKVYCSFCGKSQDEVKKIIAGNNVFICNECVALSQEI
                     IKEELAEEVLADLAEVPKPKELLATLDEYVVGQDRAKRALAVAVYNHYKRVSFAESRNE
                     EDVDLQKSNILMIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENILLK
                     LIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVP
                     PQGGRKHPNQEMIQIDTKNILFIVGGAFDGIEDIVKQRLGEKVIGFGQNNRKIDENASY
                     MQEIISEDIQKFGLIPEFIGRLPVVAALEQLTADDLVRILTEPRNALVKQYQTLLSYDG
                     VELEFDKDALQAIANKAIERKTGARGLRSIIEETMMDIMFEIPSQEEVTKVRVTKAAVE
                     GKDKPILEIA"
     gene            24376..24972
                     /gene="yihA"
                     /locus_tag="MK857_RS04645"
                     /old_locus_tag="MK857_04625"
     CDS             24376..24972
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0043022 - ribosome binding [Evidence IEA]"
                     /GO_process="GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="yihA"
                     /gene_functions="other (smcogs) SMCOG1227: ribosome
                     biogenesis GTP-binding protein YsxC"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000796923.1"
                     /locus_tag="MK857_RS04645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04625"
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="WP_048791466.1"
                     /transl_table=11
                     /translation="MMTEYLNTHNASLLLSAANKSHYPQDDLPEIALAGRSNVGKSSFI
                     NTLLGRKNLARTSSKPGKTQLLNFYNIDDKLRFVDVPGYGYAKVSKSERAKWGKMIEEY
                     LVSRDNLRAVVSLVDLRHEPSADDVQMYDFLKYYEIPVIVVATKADKIPRGKWNKHESA
                     IKKKLNFNKSDKFIIFSSVDRTGLDESWDSILDEL"
     gene            25104..25319
                     /locus_tag="MK857_RS04650"
                     /old_locus_tag="MK857_04630"
     CDS             25104..25319
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018184.4"
                     /locus_tag="MK857_RS04650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04630"
                     /product="GyrI-like domain-containing protein"
                     /protein_id="WP_082144682.1"
                     /transl_table=11
                     /translation="MYFETIPAENCVEILHIGAYDDEPISFQKMDLFAKETNVKRSKNY
                     HREIYLNNENRVSKDKLKTILYYPIE"
     gene            complement(25409..26077)
                     /locus_tag="MK857_RS04655"
                     /old_locus_tag="MK857_04635"
     CDS             complement(25409..26077)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003065192.1"
                     /locus_tag="MK857_RS04655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04635"
                     /product="YoaK family protein"
                     /protein_id="WP_048791487.1"
                     /transl_table=11
                     /translation="MPQNSRFEAILLGFLGGALDVYCQIQFDTLVATQTGNILFLIADI
                     SHSPLQQTLIRLFSVLFFSIGFMFGLHIRANAKTAFWRVYALLPLLIVTMILPLLPDIR
                     LLWVVLLALAAGLLTLTFSGSQIESHAYSILMTSGNYRKMITAWHQYFNADEKTCAMKR
                     QAINYSLVVISFVIGAITTAILYHFTHEKTIWIVTLNLACIIYHYSSVVVRYRLQACNI
                     "
     misc_feature    complement(26165..26179)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.78"
                     /tool="antismash"
     gene            complement(26186..26833)
                     /locus_tag="MK857_RS04660"
                     /old_locus_tag="MK857_04640"
     CDS             complement(26186..26833)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003065191.1"
                     /locus_tag="MK857_RS04660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04640"
                     /product="deoxyribonuclease I"
                     /protein_id="WP_048791465.1"
                     /transl_table=11
                     /translation="MQLTLYNLYQKMLTHMGATNWWPADSKQQIIIEAILIQNTTELNA
                     TRASQLIRAASNYDLQVLVNIPKENLEELVRPAGFMKNKSKAIQEVASWYLAHEENPAK
                     IVQQYGSSLRKVLLSLHGVGPETADVLMAYIFDQPQFIADKYARTLFTQLGINDLTDYK
                     SLAILLAELPQPFTFADAQEFHGLIDEFGKQYFHPVEDFQKSFLAGDQLILK"
     gene            complement(26939..29047)
                     /locus_tag="MK857_RS04665"
                     /old_locus_tag="MK857_04645"
     CDS             complement(26939..29047)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1223: ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002818.1"
                     /locus_tag="MK857_RS04665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04645"
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="WP_048791464.1"
                     /transl_table=11
                     /translation="MANNNFYGRNPFGNMDDIFNELMSNMGGYNSENRRYLINGREVTP
                     EEFAQYRQTGKLPGNAEYQEGAPSSAPKEDGILAKLGTNLTERARANELDPVIGRNKEI
                     QETAEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLE
                     AGTQYRGAFEENIQNLVKEVKDAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPAL
                     SRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAQDSFNILMGIRDLYEKHHN
                     VILPDNVLKAAVDFSIQYIPQRSLPDKAIDLIDMTAAHLAAQHPATDVKSLEKEIADQK
                     EKQENAVAKEDYEAALNAKVRIEELQKQIDNHTEGQKVTATVNDVAESVERLTGVPVSN
                     MGASDIERLKELASRLKGKVIGQDEAVEAVSRAIRRNRAGFDEGNRPIGSFLFVGPTGV
                     GKTELAKQLALDMFGSKDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVR
                     RNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTINFKNTVIIATSNAGFGNEA
                     LTGQDDKDKKIMDRIAPYFRPEFLNRFNGIIEFSHLTKEDLNDIVDLMLDEVSKTIAKK
                     GIDLVVSDAAKQHLIEEGYDEAMGVRPLRRVIEQEIRDKITDFYLDHTDVRHLKADMVD
                     GELVISEK"
     misc_feature    29414..29549
                     /db_xref="RFAM:RF00557"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
     gene            29578..30081
                     /gene="rplJ"
                     /locus_tag="MK857_RS04670"
                     /old_locus_tag="MK857_04650"
     CDS             29578..30081
                     /GO_component="GO:0015934 - large ribosomal subunit
                     [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rplJ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323205.1"
                     /locus_tag="MK857_RS04670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04650"
                     /product="50S ribosomal protein L10"
                     /protein_id="WP_048791463.1"
                     /transl_table=11
                     /translation="MSEAIIAKKAEQVEAVAEKMKAAASIVVVDSRGLTVEQDTVLRRN
                     LRESGVEFKVIKNSILTRAAEKAGLGDMKDLFVGPSAVAFSNEDVVAPAKIINDFAKDA
                     EALEIKGGAIEGSVSSKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVADNKE
                     DNAA"
     gene            30151..30519
                     /gene="rplL"
                     /locus_tag="MK857_RS04675"
                     /old_locus_tag="MK857_04655"
     CDS             30151..30519
                     /GO_component="GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA]"
                     /GO_component="GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rplL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /locus_tag="MK857_RS04675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04655"
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="WP_003065188.1"
                     /transl_table=11
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAGG
                     AADAGAAKDSFDVELTSAGDKKVAVIKAVREVTGLGLKEAKALVDGAPANVKEGVATAE
                     AEEIKAKLEEAGASITLK"
     gene            complement(30801..30965)
                     /locus_tag="MK857_RS04680"
                     /old_locus_tag="MK857_04660"
     CDS             complement(30801..30965)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /locus_tag="MK857_RS04680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04660"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_231729927.1"
                     /transl_table=11
                     /translation="MSDVSRRTFYRYFVNKNELLNHYFEQIINRYLTERKYFTETDNFQ
                     DILAESMNF"
     misc_feature    complement(31092..31106)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: medium, score: 22.82"
                     /tool="antismash"
     gene            complement(31510..32460)
                     /locus_tag="MK857_RS04685"
                     /old_locus_tag="MK857_04665"
     CDS             complement(31510..32460)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003065091.1"
                     /locus_tag="MK857_RS04685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04665"
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_003065091.1"
                     /transl_table=11
                     /translation="MEKRRQHQKHSNKPLAIINIILLIACIVASVFLFIALKENNFIFS
                     TTKTEQVSSSSASHTNTTTTSSASTVTSDSSSANTNENEVNWVKQDSNVSVPILMYHAI
                     HVMAAEEASNANLIVDPTTFESHIQRLSEEGYYFLTPEEAYKVLTENVLPNDNSKIVWL
                     TFDDSLWDFYDNAYPILQKYGAKATNNVITSTVGNSGNLSLDEMLEMKANGMSFQDHTV
                     THPDLSASDNATQTSEMEDSKNYLDTNLNQDTIAIAYPAGRYSDTTLQIAANLNYKLGV
                     TTNEGIASASDGLLSLDRIRILPTTTADSLIASIS"
     misc_feature    32565..32579
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     strong, score: 24.54"
                     /tool="antismash"
     misc_feature    32841..32856
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.44"
                     /tool="antismash"
     gene            32881..34167
                     /locus_tag="MK857_RS04690"
                     /old_locus_tag="MK857_04670"
     CDS             32881..34167
                     /EC_number="1.1.1.3"
                     /GO_function="GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019313981.1"
                     /locus_tag="MK857_RS04690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04670"
                     /product="homoserine dehydrogenase"
                     /protein_id="WP_048791462.1"
                     /transl_table=11
                     /translation="MSIKIALLGFGTVASGVPFLLKENPSKITEAAHDTIEITKVLVKD
                     DDERNRLLAAGNDYNFVTNIDDILSDDSIDIVIELMGRIEPARTFITKALEAGKNVVSA
                     NKDLIATHGKELIELAKDKGVAFYYEAAVAGGIPILRTLANSLTSDKVTRILGVLNGTS
                     NFMMTKMVDEGWTYEDALKTAQDLGYAESDPTNDVEGIDAAYKAVILSQFGFGMTIDFD
                     DVAHKGITTITPDDVAVAQELGYVIKLVGDVREVESGISAEVSPTFLPKAHPLASVNDV
                     MNAVFVESIGIGESMYYGPGAGQKPTATSVTADIIRICRRIKDGNVGKPFNEFVRETKL
                     ANPADVKSHYYFAINTPDKKGQLLRLAEIFNSEDISFEQVLQQKANGTRARVVIITHSM
                     SKTQLADVTAKLEAVEDFQVVNTLKVLGE"
     gene            34225..35091
                     /gene="thrB"
                     /locus_tag="MK857_RS04695"
                     /old_locus_tag="MK857_04675"
     CDS             34225..35091
                     /EC_number="2.7.1.39"
                     /GO_function="GO:0004413 - homoserine kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thrB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294652.1"
                     /locus_tag="MK857_RS04695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04675"
                     /product="homoserine kinase"
                     /protein_id="WP_048791461.1"
                     /transl_table=11
                     /translation="MKITVPATSANVGPGFDSVGVAVSKYLTIEILELSERWEVLHDLG
                     DVPSDETNLLITTALQVKADLQPHRIKMVSDIPLARGLGSSSSVIVAGIELANQLAHLQ
                     LSADEKLVIATKIEGHPDNVAPAIFGNLVISSYVNEKVNSAVVAFPEASFVAFIPNYEL
                     KTSDSRNVLPNEFSYKEAVAASSIANVAIAALLTGDLEKAGKAIEADLFHERFRQKLVK
                     EFAPIKEVAHEVGAYATYLSGAGPTIMVLAPKAKEAELVECLAALALDGEVVALHVDTK
                     GVFVEKD"
     gene            35078..35965
                     /gene="rarD"
                     /locus_tag="MK857_RS04700"
                     /old_locus_tag="MK857_04680"
     CDS             35078..35965
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /gene="rarD"
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003065078.1"
                     /locus_tag="MK857_RS04700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04680"
                     /product="EamA family transporter RarD"
                     /protein_id="WP_048791460.1"
                     /transl_table=11
                     /translation="MKKTNLGILFGLITYILWGFLSLYWKLLSGVNSYNTFSYRIIFTV
                     LTMLVYMVLSKNKERYRGEIRQLISHKQELAMAVLASFLIALNWLTYIFAVSHQQATQA
                     SFGYYIMPLVSILLALVFLHERLTPWMTAAIIIAGIGVGILAINTGQAPLVSILLAVTF
                     ALYGLVKKNVKLSSDVAMLIESSVVAPFVLIYLLFFSKESLLDYSLLENVLLLASGIVT
                     AIPLLLFAEAVKRAPLNIIGFIQYINPTIQLAIAVFVFHEKVGNGEVSGFIFIWIAIAI
                     FILGQLMSLRKKSR"
     gene            35981..36175
                     /locus_tag="MK857_RS04705"
                     /old_locus_tag="MK857_04685"
     CDS             35981..36175
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MK857_RS04705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MK857_04685"
                     /product="hypothetical protein"
                     /protein_id="WP_003065075.1"
                     /transl_table=11
                     /translation="MHKKTVVDFKELGHQLIFENPVRILATKLIGDVDAILKKVVHKDI
                     VLLVMSVMRQEKYLKTIFL"
     gene            36199..36402
                     /locus_tag="MK857_RS04710"
     CDS             36199..36402
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012640.4"
                     /locus_tag="MK857_RS04710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="chorismate-binding protein"
                     /protein_id="WP_003065073.1"
                     /transl_table=11
                     /translation="MNITMPQVWESKTDKDEYEKAISEIRQQIRQGNIYQVNYTVQLHN
                     RINSNLFELYNRIVIEQGAKYN"
     misc_feature    36450..36463
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.95"
                     /tool="antismash"
     misc_feature    complement(36451..36464)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.52"
                     /tool="antismash"
     gene            36474..36632
                     /locus_tag="MK857_RS04715"
     CDS             36474..36632
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012640.4"
                     /locus_tag="MK857_RS04715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="chorismate-binding protein"
                     /protein_id="WP_253066431.1"
                     /transl_table=11
                     /translation="MTIRPMKATIARGINDAQDFRNKHWLANDSKNRSENMMIVNLLRN
                     DTGRILG"
     gene            36899..37279
                     /locus_tag="MK857_RS04720"
                     /old_locus_tag="MK857_04695"
     CDS             36899..37279
                     /NRPS_PKS="Domain: Aminotran_4 (1-126). E-value: 9e-11.
                     Score: 33.9. Matches aSDomain:
                     nrpspksdomains_MK857_RS04720_Aminotran_4.1"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MK857_RS04720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MK857_04695"
                     /product="aminotransferase class IV"
                     /protein_id="WP_231729926.1"
                     /transl_table=11
                     /translation="MGWPFSETEFLDKISKLLKTLDLSDYRLRVLLHKSGEVSMLEDLP
                     STFLQAKLVQREEACDFPFTYFKTSYRPHIPNSDKEQVFISSDGYPQETSIGNIILEIN
                     GTYYTLIVEVGILDGMHRKYFI"
     aSDomain        36902..37276
                     /aSDomain="Aminotran_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MK857_RS04720_Aminotran_4.1"
                     /evalue="9.00E-11"
                     /label="MK857_RS04720_Aminotran_4.1"
                     /locus_tag="MK857_RS04720"
                     /protein_end="126"
                     /protein_start="1"
                     /score="33.9"
                     /tool="antismash"
                     /translation="GWPFSETEFLDKISKLLKTLDLSDYRLRVLLHKSGEVSMLEDLPS
                     TFLQAKLVQREEACDFPFTYFKTSYRPHIPNSDKEQVFISSDGYPQETSIGNIILEING
                     TYYTLIVEVGILDGMHRKYFI"
     misc_feature    36925..36938
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.06"
                     /tool="antismash"
     gene            37848..39101
                     /locus_tag="MK857_RS04725"
                     /old_locus_tag="MK857_04700"
     CDS             37848..39101
                     /EC_number="6.3.2.-"
                     /GO_function="GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013643148.1"
                     /locus_tag="MK857_RS04725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04700"
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="WP_048791459.1"
                     /transl_table=11
                     /translation="MNYQEALDWIHSKLKFGIKPGLERMAWILEELGNPQEKLSAVHIV
                     GTNGKGSVTSYLQHIFSLAGYEVGTFTSPYIVNFRERISLNDQMISETDFLDLVERVRP
                     VVERLPLETTLEPATEFEVITVLMFEYFGHMHPVDIAFIEAGMGGLYDSTNVFKALAVI
                     CPSIGLDHQNVLGQTYAEIAEQKAGVLKEHVPFIFATERDDVHRVFLKKAQACGSQTYE
                     FKKDFSVNETENGFDYQGQENIEDIRLAMPGKHQISNASLAITAALLLSKTYPKVTKEI
                     IKSGLAQTHWVGRTELMFPNVMIDGAHNNESVQALVNVMQAYKDKNLHILFAAIDTKPI
                     DSMLALLSQLAEVDVTTFEYHNSLALENYPEQYHKVPDWKDWVKHIDSDSKDDFYLITG
                     SLYFISQVRPVLLSRQQN"
     gene            39139..39702
                     /gene="folE"
                     /locus_tag="MK857_RS04730"
                     /old_locus_tag="MK857_04705"
     CDS             39139..39702
                     /EC_number="3.5.4.16"
                     /GO_function="GO:0003934 - GTP cyclohydrolase I activity
                     [Evidence IEA]"
                     /GO_process="GO:0042559 - pteridine-containing compound
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="folE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GTP_cyclohydroI"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004232021.1"
                     /locus_tag="MK857_RS04730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04705"
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="WP_048791458.1"
                     /sec_met_domain="GTP_cyclohydroI (E-value: 1.2e-80,
                     bitscore: 263.3, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANQEKLELAVYQLLEALGENPEREGLLDTPKRVAKMYQEMFSGL
                     NEDPKDQFTAVFTENHDEVVLVKDIPFYSMCEHHLVPFYGKAHVAYLPSDGRVTGLSKL
                     ARAVEVASKRPQLQERLTDQVATALEEALHPKGVFVMLEAEHMCMTMRGIKKPGSKTVT
                     TVAKGIFKENREERNEILSLILGK"
     gene            39740..40540
                     /gene="folP"
                     /locus_tag="MK857_RS04735"
                     /old_locus_tag="MK857_04710"
     CDS             39740..40540
                     /EC_number="2.5.1.15"
                     /GO_function="GO:0004156 - dihydropteroate synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="folP"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013851895.1"
                     /locus_tag="MK857_RS04735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04710"
                     /product="dihydropteroate synthase"
                     /protein_id="WP_048791457.1"
                     /transl_table=11
                     /translation="MKIGKYEIDGTACIMGILNVTPDSFSDGGSYTSIENALAQAEKMI
                     AGGAKIIDVGGESTRPGYTFVEAEEEINRVVPVISALKERFDVLVSIDTYKTETARAAL
                     EAGADILNDVWAGLYDGKMLALAAEKNVPIILMHNQEEEKYDNITKEVCDFLTERAQAA
                     LDAGVTLENIWIDPGFGFAKNEAQNIELLKGLDAVCKLGYPVLFGMSRKRTVDYLLGGG
                     TLAAERDMGTAALSAWAVAKGCQIVRVHNVDVNRDIVKVISQLS"
     gene            40607..40969
                     /gene="folB"
                     /locus_tag="MK857_RS04740"
                     /old_locus_tag="MK857_04715"
     CDS             40607..40969
                     /EC_number="4.1.2.25"
                     /GO_function="GO:0004150 - dihydroneopterin aldolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006760 - folic acid-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="folB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854334.1"
                     /locus_tag="MK857_RS04740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK857_04715"
                     /product="dihydroneopterin aldolase"
                     /protein_id="WP_048791456.1"
                     /transl_table=11
                     /translation="MDKIHLKGCRFYGYHGAFAEEQTLGQIFVVDCTLSVDLQKASQSD
                     VLEDTVHYGLVFETIKRQVEEERYALIERLAGAICQDIFEQFPPVQAINIKIFKENPPI
                     NGHYDVVGIELERERA"
ORIGIN
        1 gaagagacga cggacgagca acgtttgcca gttggtcaaa aaatcatttc gattatggga
       61 gaaatgggac gtgattttga tggatcgtat gctgaatatg tccctttgcc aaatgagcag
      121 atttatccta tctcaacgca gttggattgg gcaacattgg cgacgattcc agagacttat
      181 tatactgcct ttggtgctta tcaaaattta aaaatcacct cccgtgatac ggttttggtg
      241 cgtgctggtg ctagtggtat cgggacggct tttgtgaaat tggtaaaagc taaatttcct
      301 gacgtgaacg tctatgcaag tgtgcgcaat actgctaaaa aagcgcagct tttggacgct
      361 ggatatgatg atttggttat tgatgataat ggtgtgctaa agacggatgt gacattcacg
      421 aaaatcttag aattagttgg acctgctacc atcaaagaca gtctagggca tttgcaagaa
      481 aacggaatta tttgttcctg cggtcaattg ggacgaaaat ggtatctgga agaatttgat
      541 ccaattatgg aacttaaaaa taatgtctat ttgacaacat tttattcagg caatgtttca
      601 caagataaga ttcagaaaat gttagcttat attgagaaag aacaagtaga tgttcgccct
      661 gagcgcgtat ttgatttgga tagtatccaa gctgcacatg attatcttga tagtgttgca
      721 gcatttggca aggtcattgt tttaaataag gaggaaaatt ttagtgataa gtaatgcaaa
      781 aaaatacgct cgtttgcgtg atgagcaatt ttccctctat gaaagctacg ctaaaaagca
      841 tgggctaaat agtaaatcgt tattagtttt tatgtggatt tatcataatc cacatggaat
      901 gacacaggag agcattgcaa aacgaacatt ttcaacgaaa caagtgattc aagcaattgt
      961 taaaacttat atgaaaaaag gaatattata tttggagcct tctcgaattg acaggcgcaa
     1021 gaagttgatt cgtttaactg aaacaggtca gcagtttgct gctgaattat tggatccgtt
     1081 agcagatttt gaagcgcaag caatgagcgc tttgactttg gaagaacagg aagttttatt
     1141 gtcagcgaca gcgatgttca ctgataggtt aacagaactt ttagaaagtc atcaggtaaa
     1201 ggaacatgtt aaatgatata gctgcatatt ttgcagataa tggaaatact tatttaggat
     1261 acgtttggca acacattagc ctaagtttcg aggctttggt gattgcctta atcatcgctc
     1321 taccacttgg ctatttttct tatgaaaagc cgtttgtacg acaattgtca acgcttttga
     1381 cgcaagggct acgcgttatt ccaagccttg gaatcttatt tattttgatt ccattcattg
     1441 gagtggggcg cttacctgcc ttgattgctt tagtgatttt gggaatacca cccattttat
     1501 taaatacgat tgttggggtt gcgtcggttt cagaaaattt gctagaaaca gctttgggac
     1561 ttggtatgac aaggtcgcaa ttattaacaa aagtccagtt tccgttagct ctgccacata
     1621 ttttaaatgg cattaaattg gcattggtgg aaattattgc tagcgcaacc ttggcgacct
     1681 atattggagc aggtggactt ggtactttga tttttacagg attaggactt tatcgttatg
     1741 atttattgct aattggtggt ggttcggttg cgatattgtc gttccttagt atgattattt
     1801 ttgatttaag cataaaagga gtagaacatt atgaaaaata aaaaggtgat ttcaggagcg
     1861 ttactggtag tcattttggt ggcaattgtt ggtgggattt gggcgtggcg caataatcaa
     1921 tcttctgaag tgcagcaatc gtcaaccact attcgtgtgg ggtcgaaaga ttttacggaa
     1981 aatctagtca ttgctgaaat ttatgcgctt gcgcttgagg acaatggtta taccgtcgag
     2041 cgtgtgtcaa atatttcaag ttctttgatt cataattcaa ttgtcaatga tgagattgac
     2101 ttatatccag aatatacagg aactggtttg ctgtcagttt tgggtgagga tatggaaaca
     2161 gacccagaga aagtttataa gactgtcaaa aaagagtatg aggaacaatt taacctgact
     2221 tggcttgatt acgcgtcagc aaatgatagc caaggtttgg ttattcgtac ggaagtcgcc
     2281 aattcactca acatcaagac gatttctgat ttgcaagctc atgctagtga attgcgcttt
     2341 gcttcacaag gggaatttga tgaacgtgaa gatggtttac taggacttga aaagacttat
     2401 ggtaccttta actggcaatc ttcgaaggtg tatgataata gtttgaaata cagtgttctt
     2461 gaaaatgatg aggcagatgt aacgccagct tacacgaccg aaggtcagtt ggttagtacg
     2521 gataaattca cattattgga agatgataaa cagttctggc caccttataa tttagcgccc
     2581 gttgtgcgag ataatatttt ggatgacaat ccagatatta aaaccatttt aaataatatt
     2641 tcggcaaaac ttgatactga aacagttacg gaacttaatg ctaaagtgga tgttgacggt
     2701 caagaatata cagatgtcgc gaaagaatac tacgatagca taaaaggtta gaaagataga
     2761 tttatgacag aaaagacaat gattcaattt gagcatgtga gcaaagttta tggtgataaa
     2821 acggttgtta atgatattaa cttaaccatt gaaaatggcg aatttatcac aattttggga
     2881 acatcaggtt ctggtaagac aaccatgcta aaaatgatta acaagctgat tgaaccaacg
     2941 tcagggacga ttttctttgc tgggcaagat attgagcaga tggattccgt tagccttcgt
     3001 cgtcagattg gttacgttgt ccaacaaatc ggcttatttc cacatatgac ggttgctgaa
     3061 aatattgcaa ctgttcccaa gttattgggc tgggataagg aacgcattga aaatcgtgtg
     3121 ggagaacttt tagatttggt gcaattgcct gcagtggatt acggcgaacg ttatccgagt
     3181 gaattatctg gtggtcagca gcagcggata ggtgttgcgc gtgctttagc tgctgaccct
     3241 gatgtcatgt tatttgatga accatttggt gccattgatg ccattactcg taatgattta
     3301 caagaggaat tgcaagcgat tcatcagaaa ttaagtcaaa agacatttgt ttttatcact
     3361 cacgatattt atgaggcatt taaactggga acacgcgtgg ttatcatgga taatggtacc
     3421 atttgccagt ttgacacacc agaaaatatt atcaaaaatc caggaaatga atttgttcaa
     3481 agattgataa caactgcgca ggaacaagaa aaactgtgga gggctagcta tgattgatta
     3541 ttttaagaca tcttctgata agttaatcac ggcgctcatt gaacatattg aattgacgag
     3601 cttttcccta ctgtttgctt tgttatttgc tagtgtcatc acggtaattt tgctgtttta
     3661 ccctaaaata aggctggctt ctgtttacgt cttatcgcta ttgtacgcca ttccgagttt
     3721 tgcgctattt accttgttga ttcccgtgac aggtctgggg acgcgaacag ccataatagt
     3781 tttggtaatc tatgcacaat atacgttagt tcgcacattt ttagcaggat tgacacaagt
     3841 tgatgacagt attgttgaag cggcgactgg tatggggatg acaaggtggc aaatattagc
     3901 aaaaattcag ttgccattgg cgcaatcctc tatttttgca ggattacgtt tggcagcaag
     3961 ttcaatgatt gctatcgcaa caattgcctc aacgattaat gcaggcggtc taggtagtat
     4021 tttgtttgac ggactccgca caatgagttt gcctaaattg ctttggggta tcattttgac
     4081 tgttgcccta agcttattag tcaacctcat cttgtatctt gttgaagaat tagtcaagaa
     4141 cgaaagcgtg agttaatgcg tcttgcaata ataagaacac aaaccaagaa gttgggcatt
     4201 ttgctcaact ttttagctct taaaaatgcc ccttttagct tcttataagg aattttgtta
     4261 taatgaaact atcatctagt taggaaaagt tatgacagat atgatttatg gagaatatgc
     4321 ggattacctg cctttgattt tggaggactt tagtcagcgt attcgcaaga aaaatgatga
     4381 ggttaaaaaa gagactggtt ataagttgtt tgaacatttt atcgctcgcg ttaagacacc
     4441 tgaaagtatg acagagaagt gtcaacgcaa aaatcttcca gtaacaaccg agtctgcctt
     4501 gaaaaaagtg cgtgatagta ttggtctgag gataatatgt ggttttgttg atgatattta
     4561 tactttagtg gaccttatcc gttcttttga tgattgcacc attgttgctg agaaagatta
     4621 catcaaaaat gcgaaaccaa atggttatcg ttcttaccat ttgatagtag aggttgtgac
     4681 gccttatcct gattgtttgg gaaataggca gggatcatat tttattgaaa tacagcttcg
     4741 taccattgct atggattctt gggctagttt ggaacatcaa atgaagtata agcatgatat
     4801 taaagaccca aaacggattg tccgtgagct caaacgctgc gcagatgaat tagcgtcttg
     4861 tgatttgacc atgcaaacca ttcgaaacct catccaagaa agctcccaag attaatgaat
     4921 atgagctacg ataggagata gcatatgaaa atattagttg cagaagatga aattcaaatg
     4981 aatcgtgtgt tgactacggc gttaacccat gaaggttatg atgtggattc ggtttatgat
     5041 ggacaggcag ctattgatat ggcaactgaa aatgcctatg acgttatggt catggacatt
     5101 atgatgcctg tcaaatctgg catcgaagct gtgcaagaaa ttcgtcaaac aggcaaccag
     5161 tcacacatta ttatgttgac tgccatggct gaagttgatg accgtgtgac aggcttagat
     5221 gctggagcag atgattattt gaccaaaccc ttttcattaa aagaactatt agcgcgtttg
     5281 cggtcgatgt cacgtcgtgt ggataccaat ttcacgtcta atattttgac cgttggaaca
     5341 gttactttga atgttggtga gcaggaactt gtcagtcaaa acactattcg cctagcaggg
     5401 aaagaatcta aaatgctgga attcttcatg ctcaatgcag gtaagaaact atcaaccgac
     5461 cagattttta accatgtttg ggcaaatgac aaagatgacc cagagattga taatggctat
     5521 gtttttatct acgtttccta ccttcgtcaa aaattgaaat caattggtgc aaatgtagtg
     5581 attgagggcg aggaaatggg tggttatgag ttgaaagaat tgtaggtgat gccatgtttc
     5641 gaaaattaag gcttcgtttt attgcgatta cctctttagc aattctgatt gtattgtttt
     5701 cagtggttgg ggtgctcaat tctgcccgtc acattcaaaa ggtaaatgaa atcaacaaga
     5761 ttttaacctt gatttcagat aatggcggaa cctttccaag cgtctccaaa gtaactagtg
     5821 aattgggtga tactgtttct gtcgatacgc tctttcaata tcggtatttt agtgctgttg
     5881 ttgataagga tggcaatatc acttcgttaa atttgagcag tatttctgat ttgaccaacg
     5941 agcaagtgga aaattacctg attaagatta ataaatcagg tgatacgaga ggtgattttc
     6001 gttacagtaa tcacacctat tcttatcttg taacggacga atcagatgat tcgacattga
     6061 ttgtggtctt ggactcaaca aatcaagtcg aggaaaatat gacactagtt catctttcct
     6121 tatggatgtc aggggttagt tttgccttct ttgttctcat ggtttctatt ttttctggta
     6181 gggttattga gccttttatc cgaaattatg aacggcaacg tcgttttatc acgaatgctg
     6241 gtcatgaatt aaagacacct ttggcgatta tttcggctaa taatgaattg gttgagatga
     6301 tgaacggtga atcagaatgg acaaaaagta ccaacgacca agttgaacgt atgactggct
     6361 tgattaatag tttggtggct atggcccgct tggaagaaca acctgaagta gtattgactg
     6421 atttgaattt ttcagcaatt gctgaagatg ctgccgagga ctttaagggt cctgtcatca
     6481 aagacggcaa gcaatttatt atggaaattc aacctgatat tcatgtcaaa gcagaagaaa
     6541 aatcactttt tgaattggtg acccttttgg ttgataatgc caacaaatat tgtgatgcag
     6601 gaggaacggt ctcagttaaa ttaagcaaag ctaatcgcct ctcaaaagca cgtttggaaa
     6661 tttccaatac ctacgtcgaa ggcaagaacg ttgattatag caaattcttt gaacgttttt
     6721 accgtgaaga tgaatcacat aataacaaaa aatcaggtta tggtatcgga ttgtcaatgg
     6781 cacagaccat ggttaaactc ttcaaaggaa gcattagcgt ttcttatagc ggagatacca
     6841 ttacattctt agtaagtttg taggggcgaa aactctaaag ctgatttgca agtagagtaa
     6901 gcaacactct aataacttac tttctcctgt tcaaaactcg ttaacatcaa caaaagacga
     6961 tttccgtttg gaagtcgtct tgttttacta ttgtatataa actcgttttc tgacttacaa
     7021 gcccaataag cgttggacgt gttctgggct ttcatttggt ccgtagttgt ttggaaaacg
     7081 gtcgagtgcc tgaatttgct tgatgtcatc tggtgtgagt tcaaaatcaa aaatatcaaa
     7141 gttttctttc atgcgttcta agtgaacgga ttttggaatg gtaaggatat cgttttgaac
     7201 ttgccaacgt agaatgactt gtgccacagt cttgccatgt ttttcagcta tgctattgag
     7261 cgtagcgtcc ctaaaaatat tatcttctcc acggttgaaa gggctccaag cttgggtagc
     7321 tatgccaaat tgggcattgg cagcttgaat gatagggtgt tgtttgtagg ggtgaagctc
     7381 aatttggttg agtgctggca caacttcggt attgagcgca aaatctgtta aacgtccagt
     7441 agagaagtta gaaaccccaa tagcacggat atatccttcc ttataaagct caatcatcgc
     7501 acgccaagcg ccatgagtat caccgtatgg ttgatgaatg agataaaggt caaggtaatc
     7561 agtatccagt ttgcgtagcg tttcctcaaa agcctttttt gtttcggtat aaccaaggtg
     7621 gtcaatccag actttactag tcagaaagac atcttcacgt gaaagactag aagccttcat
     7681 cgcacgcccg acagcttctt catttttata aatagcggca gtatcaatta aacggtagcc
     7741 cacctcaagg gcgttttcga ctgattcttg gcattgtgct tggtcgaaaa tttgccaaac
     7801 accaaagcct aaaacaggga tttggatacc attatttaac gttttaaaat tcataatgtt
     7861 tcctccttag tttcatttta gcacaaaaaa aagcaaaata atggtatgaa gattgcttta
     7921 tcagtttgct tcaggaaagt cattgaggct tttcttgatt tcttgaataa aggctgttcc
     7981 aatttttgaa acttttttct ttttattggt cacatatcca agggtatgtt taggactatc
     8041 ttgcagagga atgaggacaa tttggttacg aacgaagcta tttacaattc caagaccaga
     8101 ggcgtaggcg tctgttgcac aaagtaaatt catgactgtt ccacggtcat tgctatagag
     8161 cacgtgctgt gtattgtgaa tttgtaaggc atcctcgtca aaattcaaac ctgattgttc
     8221 ctgacggaag cgaatttggt cgtaaccttt taagtcgctt tcagaaatga catccttatg
     8281 tgccaatggg tgattgcgtc taagaaaaac acgtgttgga aaatcaccca aagacgtaaa
     8341 ttccaaatca tggtgttcca gggaagattc caaaatatgc ttattttcgt catccagata
     8401 aataataccc aaatcagctt caaaacgagc aacactttcc aaaattttct tagtggtcgt
     8461 ttcaatcgtt tgaaattctt gataatcttg attgaattct tgggcaacct ttgccaacgg
     8521 aattgacaag aaatcataat gatgcgatgc taccgtgaaa ctctttttaa attggtcatg
     8581 gtaacgttgc tcaagcaaat caagctcacc gataatacgt ttggcatatt tcaaaaaatc
     8641 atagccatct tcagttgtat tggaacgtgt gaacagttga acccctaatt cattttctaa
     8701 atccttaata gaacttgata aattgggttg agtcataaat aattccttag ctgcctgact
     8761 aaaagaacct acacgagcga ctgcttcaac ataacgacat tgttgaaaat tcataaaacc
     8821 tcatcccttc atcataatag ttgttgtcat tatagcaaaa ataagattaa aaaatcagta
     8881 aatttctgat agaaaaaaat aaagccgtga taagattttt gtataacctg tcattagttt
     8941 tctagattat aagcagattt tatggataat aataaaaaat ttagattata cgaatgaaaa
     9001 gagacgtggt aagataggat tactaaaaat cttgaaggaa gacgtgtcta tgatagtaac
     9061 cgaaaagcag ttaagaaaca tttcaatagt aacactaatc atttttgtct tatctcttct
     9121 tattttttga aaatatctcc ttttaaccca ttgatttctg attaccagag ctctgaaatc
     9181 acgaaagaag atttacagta tcttaattgc ttaaaaagtt tgacacattt gccttgaaga
     9241 taaaaagtca gtcgagagaa tatcttgact ggctttttct ttggttttcg ctataagcaa
     9301 atcttatggc tattcataaa aaatatagat ttttcaagta taaaaatgca tgatagtata
     9361 attgtcatac caaaagcaaa ggagaaacag attatgacaa caaagagaga atgggtttta
     9421 aaagcattta aaaatgaaaa agtcgacaaa gttcctgtcg gattttggta tcatttcaca
     9481 acggatgatg aaagaggcga cggttttaat cctgagattt tcaataaaaa tatcgcagga
     9541 cataaaaaat tcgttttaga cgtcaatcca gattttgtca aggtgatgag tgatggcttc
     9601 ttcacttatc ctaatgaaca aattcatcaa ggcgtcactt ctatcaaaga attagaagga
     9661 attgtctcta tcggtgaaaa tcatccttgg attacacaac aagttgaatt agccaaaaaa
     9721 atacgtgaag atttcccaga agatattgct tctttctata atatttttgc tcctgtgact
     9781 tatttgaagt ggcaattggc aggaaaaggt ggcaatggtg atgaaatcat tgaaaacttt
     9841 atcaaggaag acgctgaatt gactaaagaa gttttggacg tggttgctgg cgacattggc
     9901 atcctaacaa aacgtttaat taaagaagca ggagttgacg gtatttacct cagcgttcaa
     9961 aatttgcaag attcacgttc aagcaaagaa gaatacaacc aagtgattaa accaggtgag
    10021 cttcacattt tgaatcgtgc gatttctgct ggtggtacga atattcttca catctgtggt
    10081 tatgaaggcg caacaaatga cattatgtat tacacagatt atcccgcaga tgtcattaac
    10141 tgggcagttg aattggaagg tgtcagctta tcagaaggac gtcaattgtt cggtggcaaa
    10201 acagttcttg gtggctttga aaatactgaa aaaggtttat tataccttgg cagtaaagaa
    10261 gctattcaag gaaaagtcaa agaattgctt gatgaagcag gacgtcaagg cgttgtgatt
    10321 ggagcagatt gtaccgtacc aagtgatatt tcgtcaaaac gtattgattg ggtgaaagaa
    10381 gcagttgctt tatgagtttt taggaaaagg agtggatgta tatgagtaag aaaaaatgga
    10441 ttgttgctgg tggaattgtt gtagcgcttg ttgcagcgac agtaattgga cgtcaattaa
    10501 caggtaagac gaccgcaagt gctcaaagct catctggcga ttcagacaag gtgactaccc
    10561 ttcaagtcgc tcatacacaa aactatgtgc catacgatta tgtcgatgaa aatggtgaaa
    10621 gtgacggatt tgaagttgct gttttgaaag ccgttgataa aaaattgaaa aattataaat
    10681 tcgaatacac aggaacaagt gacgaagatt tgctgattgg tcttgaatct ggaaaatacg
    10741 atattggtgt caaaggtgca tggtacactg ctgaacgtgc tgaaaaattt gtgattccag
    10801 acgaagccat tggtgctagt gtgattggct ttgccattcg taaagaagat gaatcaaaat
    10861 acacagatat cgattcattt gctaatagcg gtggtaaact cgttccaatt tcaccacaaa
    10921 atgctcaata taatgtgatt caagagtaca ataaaacagc taaaaatccg attgaattga
    10981 tagaatcaga aagtttctct gttgcggatg cctatgcttg ggttcttgaa ggacgttacg
    11041 atgcttattt ctcaatcaag ttgtcatttg aagaagctgt tcaagacgaa gatggtgctt
    11101 atcatcaata tgctgaccaa ttaacatggt tcccatataa aggcattgaa acttatccat
    11161 tgattcataa aaatgctact aatgaagctt ttgctgaaga atatgataaa gctattaaag
    11221 ggttgaaaga ggacggtaca atcgcaaaac tttctgaaaa atactttgga gaagatgtct
    11281 ttagttacgt cacagactag gaggtgccta tggtttctta tgaaccatct cgtgtgataa
    11341 catttcttcc ggaaatttta tcagctttac ctctgacttt atgggtttta gtattgacca
    11401 ttttatttgg aagcttgtta ggactgtttt tggcttggtc acagttgtca ggtgaaaaaa
    11461 gcttaccctc ttttgcaaga ggatatgtct ttattttaag atgtacgccc cctattgtgc
    11521 ttatcttttt ggttttttat ggtttacctc gttttttaga atggtggtta ggcatcgatg
    11581 tcaatggttg gtctcgttca gtgtttgtta ttttagcgat gacattgttg tttgcagcta
    11641 gtatctcaga agtttttaaa tcctcttatc aagcacttcc taaaggtcaa ttagaagcag
    11701 ggcttagtat tggtttaaca gattatcaga catttgtcag aatccttttg ccacaggcgt
    11761 ttcggattgc actccccaat atcacgacag cgattattaa tctattaaaa gacattgctt
    11821 tagcctatac gattggtctg gttgatttaa tgggtgctgg aaatttggtt atttcacgaa
    11881 atctgggcaa ttattcgctt gaaacctata cagcggttgc cattatttac tgggttttag
    11941 cgttaatttt agctgttgga acacatttca ttgaaaatga gttagacacg acacgaggtt
    12001 aaggagggat tatggatttt tcttacattt tagaaacatt tgtcaaaatt ctttctggga
    12061 ttccagtaac cttgggaatt atggttgttt ccattctttt gagtttcttt ccagctcttt
    12121 ttctagcttt aggtcgcatt tataaggtga aaggtgttac gggattttca gttatttatc
    12181 tcgcctttat tcgttcgaca ccagctattt tactgatttt atttttttat agtctttttc
    12241 caagtttgat taaccagcta ttgaaagcca caggttttaa tatttttgac attaatccta
    12301 tttattacgc ttacattatt tttgggctta tgactactgg aagcctatct gagattatcc
    12361 gctctgccat tttaacggtt gataaaggac agttagaagc tgcacaggcg attgggcttt
    12421 cgaccagtca agcttatatt agaatagttt ttccgcaagc tattcgtcag gcgctaccaa
    12481 atctttgcaa cttggtgatt aatctcgtca aggggacttc tcttgttttt gtgatgacgg
    12541 tgaaagatat cacggcaatt gctaagattg aagccgctta tggttaccat tattttgaat
    12601 cctattttgt tattttcatt atttatattg tgatttgtgg gcttattcaa tacggtttta
    12661 aatttttaga aaaacgtgct caaattgttt gaggtcaagt taggagtttt ctatgttatc
    12721 agttaaaaat atcgaaaaat catttggaga taaaaaagtt ttagacggga ttagtttgac
    12781 agtcaatcaa ggtgatgttg ttgtcatctt gggaccttcg ggttcaggaa aaacaacttt
    12841 cttgcggtct cttaattatc ttgaaaaagc tgatgctggg gagttgatac tagatggcaa
    12901 gacctacgat ttggcaaaaa tcagtcgcaa ggatgttctt gaaattcgca aaaaaacagc
    12961 ctttgttttc caaaattata atttatttgc taacaaaacg gctattgaaa atattttgga
    13021 aggactagtc attgctcgca agattccaaa agaagaagct atcccaattg ctgaaaatgc
    13081 gctgaaaaaa gttgggcttt tagagaaaaa agactactat cctagtcaat tgtctggtgg
    13141 gcaacagcaa cggattggaa ttgcgcgtgc tatcgctgtg aaacctgatg tcattttatt
    13201 tgacgagccg acatctgccc ttgacccaga attgattgga gatgttcttg atgtcatgaa
    13261 agaattagcc caagaagggg tcaccatggt agtcgtcact cacgaaatga gctttgcgcg
    13321 tgatgtggca acacatgtca tctttatgga aggcggacac attatcgaag aaggcgaccc
    13381 aaaagaattc ttcagcaaac caaaagaaga acgcaccaaa caattcttaa cccgcatcat
    13441 cccagaactc aatatagacc cagtgattta aaccagtcct tgactggttt ttctattttt
    13501 ttatgataag ggctaacatt ttccagtaaa agtcgctttt tttgtggaac aatgataaaa
    13561 tggagtgtaa actaaaaatt gtaagagaag agcatgacta agaaaattgg cgtcggtaag
    13621 gcgcatagta agattatttg gatgggtgaa cattccgttg tttatggcta tcctgccatt
    13681 gcgattccgc ttcaaggaat taaggttgaa tgtcatattt atccagctga agaaaagatt
    13741 cactttgatt tttatgacac gttatcaact gccgtttatg cggcgttaga gtacctaaat
    13801 cacacagatg tttccattac ctatgcgatt cgttctgaaa ttccacaaaa acgtggcatg
    13861 gggtcatcag cagcggtttc tatcgcagct atccgtgctg tttttgatta ttttgagcaa
    13921 agcattgata tgaatactct ggaaattttg gtgaataaag cagagattat tgcacattca
    13981 aatccaagtg ggcttgatgc caagacttgt ttgagtgata aagccattac ttttatccgt
    14041 aacatcggtt ttagtaccct tgatttagat ttggatgctt atttggttat tgcagatacg
    14101 ggaatttatg gtaatacgcg tgaagctgtt gagaaggttg ctcaagcaga agaggccaat
    14161 ttaccacatc tagcagccct tggcgactta accgaaattg ttcaaaaagc tattcaagac
    14221 aaagatattc aaaaaattgg tcacatgatg accaaagcac acgctcattt acaagctatt
    14281 ggtgtcagca ttgacgtttc cgaccaactg gttaagcttt ctttgggaaa tggtgccctt
    14341 ggagccaaga tgagtggtgg cggacttgga ggctgtatta ttgcccttgc aagtaccaaa
    14401 gctgacgcag aaaaaataag taacgcatta aaagaaggag gagcggttca aacgtggatc
    14461 gaaaaattgt aacggtaaaa tcatatgcca acattgctat tatcaaatac tgggggaaag
    14521 ctgacgctat caagatgatt ccagcaacta gcagtatttc tttgactctg gaaaatatgt
    14581 ttaccacaac aactgtttct tttttaccac aatcggttgg tcatgatgaa ttttacatca
    14641 atggtgtctt gcaagatgaa aaagaacacg caaaaatttc tgccattatc gaccaatacc
    14701 gtggtggacg ttccgaattt gtcaaagttg aaactagcaa taacatgcca accgctgcag
    14761 gtttatcatc aagttcaagt ggactttcag cgcttgtaaa ggcttgtaat gaacttttcg
    14821 aaactggctt aaatcaatca gagttggcac aaaaagccaa atttgcttca ggctcatcat
    14881 cacgttcatt ctttggaccg attgctgcgt gggataaaga cagcggagat atttatccag
    14941 tgcaaaccaa tctcaaatta gcaatgatta tgcttgtttt aagcgatagc aagaaaccaa
    15001 tttctagtcg tgaaggcatg aaacgctgtg ctgaaacgtc aacaactttt gcggattggg
    15061 ttaaacaatc tgagcaagat tataaggata tgcttgctta tttggaagcc aatgattttg
    15121 aaaaagttgg agaattgaca gaacgcaatg cgcttgccat gcacgatact aacacacacg
    15181 ctaatccacc attcaattat ttgacaaatg agacctatgc agctatggat tttgttaaat
    15241 cgctgcgcgc tcaaggtgaa aaatgctatt tcacaatgga tgcaggtcca aatgttaaag
    15301 ttctttgttt ggaagaagat ttagagcgct taacaaaacg ttttgaagaa aactatcgtg
    15361 tgattgcatc acgtactaag gtgttaccag atgaaaacga ttagtgtgca gacaggtgga
    15421 aagctctata ttgcaggcga atatgccata ctaacccctg ggcaaactgc tattttgaaa
    15481 aatattccca ttcctatgac agcgatagtc aaagaagcca aaaaaatttc ccttttttca
    15541 gacatgtttg actacgctac tgatatgaca gtggataaga attacacgct cattcagcaa
    15601 accattgtca ctctggctac ttaccttgac aaatctttgc atgatttacc agcatttaaa
    15661 ctcgatatta ctggaaagtt agagcgtgac ggtaagaaat ttggcattgg gtcaagtggt
    15721 tcagtgacgg tgttaacgct caaagccttg tccgcatttt atgagctaaa gttatcagcg
    15781 gataccattt tcaagcttgc ttcctatacg cttttaaaac tgggggacaa tggttctatg
    15841 ggcgacatag cttgtattgc ttacgatgat ttggtggctt tcacctcttt tgaccgtcaa
    15901 aaagtgtcaa cgtggattgc aacagaagac atcaaaactg tacttgctaa agactggggc
    15961 tatcgtatcg aaatcatcaa acctgcgtta ctatgtgact tcttggtagg ctggacaaaa
    16021 caaccgtcca tttcaaaaga tatgattaat ttagtcaaat cggccattac aagagcgttt
    16081 cttgaggata cagaaagaaa tgttcaattc tgtaagcaag cccttcaaac gggtaataaa
    16141 atggctgtta aggcaagcct gcaaaaagtt agtgatttgt tgctcggttt aagctcagct
    16201 atttacaacg acaagttaaa ggcgttgaaa tctgctgaaa aaggtttaga tgtcattgca
    16261 aaatcatctg gctcaggcgg aggtgactgt ggtattgcaa tatcattctc agaaagcgac
    16321 agccacgaac tcgcccaacg ttggcagaaa gctggtattg aaatactata tcaagaaaga
    16381 ttaagtgatg aaagataaat taagtttagt cagaccaatt tggattgagg taaccaagaa
    16441 tgattaatcg caaagatgaa cacattaagt acgctttaaa atatcaatct ccttataatt
    16501 cttttgacga tatagagttg attcatcatt ctcttcctga ttatgattta agtgagattg
    16561 atttgcacac ccattttgcg gggcgtgatt ttgagtttcc tttttatatc aatgccatga
    16621 cgggcggttc agaaaaaggc agagctgtta atcaaaaatt ggctcaaatt gcacaagcaa
    16681 cggggcttgt tatggttaca ggctcctaca gtgctgcgct gaaaaatcct catgatgatt
    16741 cttatcctag caaagaagaa tttccagagt tgctgctagc gaccaatatc ggaattgaca
    16801 aaccttatga attagggcta caaactattc acgaaatgca gcccattttt ctccaagttc
    16861 atgtcaacct aatgcaagag cttttaatgc cagaaggtga acgtgagttt cgccaatgga
    16921 aagaaaatct cgccgattat gccacaaaaa tgccagctcc tgtcattctt aaagaagtcg
    16981 gctttggtat ggatttaaaa acaattgaaa tggctcacaa gttaggtatt aaaactgttg
    17041 atatttcagg acgtggtggc acaagttttg cctatatcga aaatcaacgt gggcataatc
    17101 gttcttacct cgatgagtgg ggacaaagca cggtccaaac gctgttaaat gctcagccga
    17161 tgattgataa gattgaaatc ttggcgtctg gtggcgttcg tcatcctttg gatattataa
    17221 aatgcttggt tttaggagca aaagcggtag gagtatcgcg agcaatccta gaactcgtcg
    17281 aaaaatattc tgttgaagaa gtcatcacaa tcattaatgg ctggaaagac gacttgcgcc
    17341 tcatcatgtg tgctctgaat tgcaaaacaa ttgccgaact tagacaggta gattatctcc
    17401 tgtacggaaa attaaacgaa gcaaaccaaa aacgctgatt cttttgaatc aacgtttttt
    17461 atatattact aaatttatca caacatgtaa taaacaatgg caatgtaatg tagcactgaa
    17521 gctagtaaaa tgaagagatg ccaaatcatg tggtcgtaag gacgttttct agcgtagaag
    17581 attgctccga tagtatatga aagaccacca gcaagcatta gtagccagaa agcaacacca
    17641 gttttgctaa caatgcttgg aataatgaaa atcactagcc agcccataag caagtagaga
    17701 aagagtgaga atctttcatt aatcttcttg gcaaaaattt tatataaaat accaaaaata
    17761 gttgcgcccc attgcaagat aataataaca tatccgagcc agccacctac taaagagaga
    17821 gcgacaggag tgtaagaacc tgcaatagca atgtaaatca tactgtggtc gataatccgc
    17881 aaaatgaatt tctgtggtga atcatattgc atagaatgat aaattgtcga tgatagaaac
    17941 atcaagaaaa ggctaatatc aaagatagac atgccgacag ctgcttctat accataatgg
    18001 tgataactat aaatggcagt gataggaagc aggacaagca ttgccacagc tccaacagcg
    18061 tgagtgacac tatttgcgac ttcttcgccg aatgaaagac gtttacttaa tttcatagtc
    18121 atgctagcat tcatcttttt ctccttctaa ttcttgaact aattggtgag tttggtaata
    18181 cagctgcaat gtttgacaag ctgaaacgac aacaggaggt aagtcgtcta tcttttcacc
    18241 attcatgcaa gcaacaaaat catcataacg tttttgtgat tggttgtccg ctgttaaaat
    18301 cgccaatgtt tggctaattt cttgaatgga aaagacgttt tttaaacttg taatgacaat
    18361 taatcgtgcc acctgcttac gactgtattt tttcttaatc ggcttttcga gatgcccatg
    18421 tttaacataa ttgttaatca tagaagccgt taatcctttt tcgttttgat gattggcttc
    18481 gccgatttgg ttgacataca gcagtacctg atctaaatat aaatctatat ctggtaattc
    18541 agaccatttt ggataagaca ttgtcataaa gttttattta cctctttatc tagtatcgat
    18601 aactagatta tataatctct aaaaaatatt gtcaagaaaa aacttcattt tggagaaata
    18661 atgtcaaaaa aatcagaaaa cttaatattt ttcgttcatt tacagttata aaaaagcgtc
    18721 cgggaggttc cagacgcttt gtctatttca gattgtttag aattgttttg gcagtttcta
    18781 aattcatatg tggtgcttgc aagagttgtt gaaccacttt gccaacttcg ttttcagtgg
    18841 caccagcaag aagtgctaat gatttggctt gcaatttcat gtgtcctgcc tgaataccag
    18901 tagaagtcaa tgctttcacg gcagcgaaat tttgtgctag cccaacagaa acaatgattt
    18961 ttgcaagtgt ttgtgcatct ggatgcccta gtagttcgtg agcgatttta acggttgggt
    19021 taagtccgat agaaccaccg cgtgttgcga ttggcattgg gagcgttaat tgaccgcgaa
    19081 gtacttgttg ctctttatca aatgaccaag ttgctaaacc acggcattgt ccgtctttgc
    19141 aagcataggc gttagcgcct gcttcgatag ctcgccagtc atttccagtt gccaagacaa
    19201 cggcatctat accattaaaa atccctttat tatgtgtggt agcacgataa acatcaactt
    19261 gagcaagttt gcttgccagt tggaatttac ttgctaatgc ttgggcttct gttttgttgc
    19321 ggctgaggta gcgaaggtca acttgacatt cggtggtaac cagcgcctgc gttgcatagt
    19381 ttgaaagaat tgccattaga ctttttccgc cagaaagttc ttccaaacta ggcactaaag
    19441 cctccatcat ggtgttgacc atattggctc ccatagcttc ttgtgtatca accgtcaagt
    19501 aaacaatcag aaactcatct ttttcttcca cagtcaattc tctagcgccg ccaccacgtt
    19561 ttacgataga agggtgagct tcattggcta aggtcaatag ctgcgcagaa tgattcaaga
    19621 tagtttcttt tgcgatagct ttgtctacca catcataaag ggcaacttga ccaatcattt
    19681 ttcgagaatg aactttggtc ttaaaaccac ctgaacgttt gatgatttta gctgcaaaac
    19741 tagccgccgc caccactgaa ggttcttcag ttaccattgg aacgttgaaa gtagcaccat
    19801 caacctgaaa atcaggagca actgaaaacg gcaaagagaa agttcccaaa acattctctg
    19861 ttagctgatt ggctgtttca agcgatagca aggtattttc ttttaagtca ttaagcgttt
    19921 cagtgcttaa aagacgatta ttttccaaat gttcaagacg ttcagttatt gcttttttgg
    19981 agaatccact ccagttaact ttagtcgatt tcgtttgttt ttccataaat tctttcgtgt
    20041 ccacgaattt ctttgagggc aaatgttcca gttttgtaat ttgcaaaaga agcattaccg
    20101 tcagcatcta aaacaggttc ttcaaagaag attctttcgt aatcttcaac agaaagagca
    20161 atacgttgtt tgagttcttg aagtcggcta tttttaagtt tgtctttgaa accttcaacc
    20221 aatgttccag tgaaaatttc agcaactgcg ccacttccat agctgaagaa agcgatattg
    20281 tcaccgccta ccaagttttc actattttca agaagtgaaa ggagtccaag gaagagtgaa
    20341 ccagtgtata tatttccgac ttgtttacta taaaggatag aactttcaaa gttagcttta
    20401 agtttttctt gcaaatcagc tggcaatgtt ttatccataa ttttattaaa gcctttaagg
    20461 gctaattttg gaaatggtaa gtggaaacag aaagctgaaa aatcagaaag tgatgtatta
    20521 aagcgttttt gaaattctgc ccatgtcgtt ttcaacatat caaggtattg tttggttgaa
    20581 taaataccat tgacataagg cgttgttgaa taattaggac gccagaagtc cataatgtcg
    20641 cgtgtttgag caacgaaatt atcatttaag agtaaaattt gtgggtcttg tgagataagc
    20701 atggcaatgc taccagcacc ttgcgttggt tcccctgaag tgtgggctcc gtaacgagca
    20761 atgtcagaag caataacgag gacttttgat tctgggtgtt tttcaacgtg taagcgagcg
    20821 taatcaagcg ctgctgtcgc actgtaacaa gcttctttca tctcgatact acgtgcaaaa
    20881 ggttgaattc ccaaaaggtt gtgaatacaa gttgctgccg ctttactttg gtcaacagat
    20941 gattctgtcg caacgataac catatcaatg gcttctttgt catcattagt aagaatgctg
    21001 tcagcagcag aagcaccaag agttacaatg tcatcattga caggtgcaat actaagcgtt
    21061 cttaacagca aacctttgct gtacttttca gggtcaactt gacgactttc agctaaatca
    21121 tccatgttta gcatatattg tgatgtcgca aacccgattt tatcaatacc gattttcatg
    21181 aataaacctt tctgaatgat tgaactcacc tgatactaca atgtttacga gtacctgcct
    21241 agctaactca taatgagctc aaatgtctta tggcatattg agttcgtgat tattattaat
    21301 tgagtgacta aatgtccaaa gataattcta ccataaagtt gtgaaaatgc tctacaaaaa
    21361 aattatttat ttcattcgtc aaagtaatgg caaaatattt tgaatacaag aaaaatacta
    21421 gctttttttg tttatttcag ataaaatagg aaagaatgat ttttttacaa aatcaaaaaa
    21481 tccaaaggag tgaatggcat gacaaaagct gatgtgattt ttaaagaaaa tatcaaaaaa
    21541 attatggaag aaggtgtctt ttcagaaaat gctcgccctg tttaccaaag cggtggacaa
    21601 gctaattcaa aatacgttac gggagcgttt gctgaatatg atttgagtaa gggggaattt
    21661 ccgattacaa ccctccgccc tattccgatt aaaagtgcta ttcgtgaaat cttttggatt
    21721 tatcaagacc aaacgaatga tttatcagtt ttaaatgata aatacaatgt caaatattgg
    21781 aatgactggg aagttgacaa ctctggaacg attggcgaac gttatggtgc tgttgtcaaa
    21841 aaacacgaca ttatccgtaa aatattgaaa caattagagg aaaatccatg gaatcgtcgt
    21901 aatgtcatct cactttggga ttacgaagct tttgaaaata cagacggact tttgccatgt
    21961 gcttttcaaa caatgtatga tgtgcgtcgt gttgacggtg agatttacct tgatgcaact
    22021 ttgactcaac gttcaaatga tatgcttgtt tcacaccaca tcaatgctat gcaatatgtt
    22081 gcccttcaaa tgatgattgc taagcatttt ggttggaaag tgggaaaatt cttctacttt
    22141 gtcaataact tgcatatcta cgataatcaa ttcgagcaag ctcgagaatt gctttctcgc
    22201 gaatctacgg attgtaaacc acgtttggta ctcaacgtgc cagacggaac agatttcttt
    22261 gatattaaac cagaagattt tgaattagtt gattatgagc cagttaaacc acaaataaaa
    22321 tttgatttgg ctatttaatc cctcttttgt ggtcgtttcc gtatcacatt tctgtatttt
    22381 ttagggaaat ctgataaaat gaaatagacg aaatgagagg actgtatgac aaagaaaatc
    22441 gttgccattt gggcagaaga tgaaaatcgt ttaatcggag taaatgatgg cttgccatgg
    22501 cgtttaccaa aagaattaaa acactttaaa gaaacaacca tgggacaagc ccttttaatg
    22561 gggcgtgtca cctttgacgg aatgaatcgc cgtattcttc caggacgcga aacattgatt
    22621 ttaacaagag acaagtcctt tgaggcagat ggtgtaagaa tcgttcatga catggacgag
    22681 gtttttgatt ggtttaaaaa gcaggataag accctttata tcgttggtgg ggctagtatc
    22741 tataaagctt ttctaccgca ttgtgatgct attattaaaa caacggttca tggtgttttt
    22801 gaaggtgata cgtatttccc agacattgat ttgacaagct ttagaaaagt ctctgaaacc
    22861 ttcaacgaaa aagatgataa aaatgcctac gactttacca ttacagtctt agaaaaataa
    22921 aatagggaga taggaatgca aagaagtatt tttggtgtat tcacggcttt cttagcggtt
    22981 atttgtattt tatgtgccct cccagcactt agaaaaaaac gatatggatt ggcagttctt
    23041 ttgtttttaa atgcctttac aaatatagtc aataccattc atgccgtgta tggtacctta
    23101 ttttaattta gagagaatag aattagagag aataaaagat ggttggaaat cgaacaaatg
    23161 atgtaaaagt ttattgctca ttctgtggaa aaagccaaga tgaagtgaaa aaaatcattg
    23221 caggaaacaa tgtttttatc tgtaatgagt gcgtggcttt gtcacaagaa attatcaaag
    23281 aagaacttgc tgaagaagtt cttgcagatt tagcggaagt tccaaaacct aaagagttgt
    23341 tagcaactct tgacgaatat gtcgttggtc aagaccgtgc caaacgcgcg cttgccgtag
    23401 ctgtttataa ccattacaaa cgtgtttctt ttgcggaaag tcgcaacgaa gaagatgttg
    23461 atttgcaaaa atcaaacatt ttgatgattg gtcctacagg ttcaggaaaa acattcctag
    23521 ctcaaacttt ggctaaaaca ttgaatgtac cgtttgcgat tgctgatgcg acatcattga
    23581 cagaagcagg atacgttggt gaagatgttg aaaatatcct tttgaaatta attcaagcag
    23641 ctgattttaa tatcgaacgc gcagaacgcg gtatcattta cgtggacgaa attgataaaa
    23701 tcgctaaaaa aggcgaaaat gtctcaatta cacgtgatgt ttcaggtgaa ggtgttcaac
    23761 aagcacttct taaaatcatt gaaggaacag ttgctagcgt accacctcaa ggtggacgta
    23821 agcaccctaa ccaagaaatg attcaaattg atactaaaaa tatcctattc attgtcggcg
    23881 gtgcttttga tggtatcgag gatattgtca aacaacgttt aggtgaaaag gttatcggtt
    23941 ttggccaaaa taaccgtaaa attgatgaaa atgcttctta tatgcaagaa atcatttcag
    24001 aagatattca aaaatttggc ttgattccag agtttatcgg acgtttgcca gttgtagcgg
    24061 cacttgaaca gttgacggct gatgatttgg ttcgtatctt gacagaacca cgtaatgcct
    24121 tggttaaaca atatcaaaca ctattatcat atgacggtgt tgaactagaa tttgataaag
    24181 atgctttgca agctattgct aacaaagcca ttgaacgtaa gacaggagct cgtggtttac
    24241 gctcaattat tgaggaaact atgatggata tcatgtttga aattcctagc caagaagaag
    24301 tgaccaaggt tcgtgtcact aaagcggctg ttgaaggcaa agataaacca attttggaaa
    24361 ttgcgtaagg agctgatgat gactgagtat ttaaataccc acaacgcttc gcttctgttg
    24421 agcgcagcca ataaatccca ttatccgcaa gatgatttac cagaaattgc gcttgctggg
    24481 cgttcaaacg ttggaaagtc gagctttatt aatacccttt tagggcgtaa gaacctagct
    24541 cgtacatcta gtaagccagg aaaaacccaa ttgcttaact tctataatat tgatgataaa
    24601 ttgcgttttg tcgatgtgcc tggttacggc tatgccaaag tttctaaatc agaacgcgcc
    24661 aaatggggca agatgattga agaatatttg gtaagtcgtg ataatttgcg tgccgttgtc
    24721 agcttggttg atttgcgtca tgaaccaagc gctgatgacg ttcaaatgta cgacttccta
    24781 aaatattatg agattcccgt tattgtcgtt gccacaaaag ctgacaagat tcctcgtggc
    24841 aaatggaaca agcatgaatc agcaatcaaa aagaaattaa actttaataa atcagataaa
    24901 tttattatct tttcatccgt tgaccgcaca ggtttagatg aatcttggga tagtatttta
    24961 gatgaattat gataagaggc tgggttttga actgcacctc aaaagttaga cagaaaaaat
    25021 ctaacttttg aagtgttttt atatgaaatt aagttatgaa gataaagtaa aaatatatga
    25081 gatgataaaa tcaggatgag caaatttatt ttgagacaat ccctgctgaa aattgtgtag
    25141 aaattcttca cataggtgct tatgatgatg aacctatctc ttttcaaaaa atggatttat
    25201 ttgctaaaga aactaatgta aagcgttcaa aaaattatca tagagaaatt tacttgaata
    25261 atgaaaatcg tgttagcaaa gataagctca aaaccatttt gtactatcct attgaataat
    25321 gactggatgc tactttagca tcatttacct aaaatcctaa aataccccta gactagtatt
    25381 ggtactaatc taggggcgtt ttttaatatc aaatattaca agcttgcaag cgatagcgga
    25441 caacgacact tgaataatgg tagataatgc aagcgagatt tagtgttact atccagatag
    25501 ttttttcatg tgtaaaatga tataaaatag ctgtcgtgat tgcgccgatg acaaaactaa
    25561 taacaacaag ggagtaattg atagcttggc gcttcatagc acacgttttt tcatcggcat
    25621 taaaatactg atgccaagct gttatcattt tacggtaatt cccagacgtc atcagaatag
    25681 aataagcgtg tgattcaatc tgactacctg aaaatgtcaa ggttaatagc ccagctgcta
    25741 gtgccagtaa gacaacccaa agtaaacgaa tatctggcaa tagtggcaaa atcattgtga
    25801 caatcaacaa cggtagcaga gcataaactc tccaaaaggc tgttttggca ttggcacgta
    25861 tatgcaaacc aaacatgaaa ccaatcgaga agaaaagaac agaaaataag cgaatcagcg
    25921 tttgctgcaa tggactgtga ctaatatcgg cgattagaaa aagaatatta ccagtctgag
    25981 ttgcgaccaa ggtgtcgaat tgtatttgac aatagacatc taaagcgcct cccaaaaagc
    26041 caagtaaaat ggcctcaaag cgactgtttt gaggcatata ttctaattca ttcacatcat
    26101 ttccttcttt ctacaataag ctcaatactt ttattgtagc actttctcaa acagctaact
    26161 agctcatttt cagaaaaaat gacacttatt tcaaaatcaa ctggtcgcct gccagaaaac
    26221 ttttctgaaa gtcctcgaca ggatgaaaat attgtttgcc aaactcatca attaatccgt
    26281 ggaattcttg tgcatccgca aaggtaaatg gttgcggaag ttctgcaagc aatattgcta
    26341 agcttttata gtcagttaaa tcattaattc ctaattgtgt aaataatgta cgagcgtatt
    26401 tatcagcgat aaattgcggc tggtcaaaga tataagccat gagaacatca gcagtttctg
    26461 gtccaacacc gtgcaaagac aataagactt ttcgcagtga gctaccatat tgttgaacaa
    26521 tctttgcggg attttcctca tgcgccaaat accaactagc tacttcttga atagccttac
    26581 ttttattttt cataaaacca gcagggcgga caagttcttc taagttttct ttaggtatat
    26641 tcaccagcac ttgcaaatcg tagttgctag ctgctctgat aagttgtgaa gccctagtag
    26701 cgtttaattc agtcgtattt tgaatgagaa tagcctcaat gatgatttgt tgcttggaat
    26761 cagcaggcca ccaattcgtt gctcccatat gtgttagcat tttttgataa agattataaa
    26821 gtgtgagttg catatcatta tcctttgtaa actttttagt tattctattt tatcaaaata
    26881 ccatagaaaa agcccaactt ctgtgagttg agcttaatag gagtgtttaa aatacggatt
    26941 atttttcgct gatgactagt tctccgtcaa ccatgtcagc tttaaggtgt ctaacatctg
    27001 tgtgatcgag atagaaatca gtgattttat cgcggatttc ttgttcaatg acacggcgga
    27061 gtggtcgaac acccatggct tcatcataac cttcttcgat aaggtgttgt ttagcagcat
    27121 cactaaccac caaatcaatg cctttcttgg caatagtctt gctaacttcg tcaagcatta
    27181 agtcaacaat gtcgttcaaa tcttctttag tcaagtgaga gaattcaata atgccgttga
    27241 aacggttaag aaattcaggg cggaagtatg gggcgatacg atccataatt ttcttgtctt
    27301 tatcatcttg accagtcaaa gcttcattgc caaatccggc attagaggta gcaatgatga
    27361 cggtattttt aaagttaatc gtattacctt gaccgtctgt caaacgacca tcatccaaaa
    27421 cttggagaag aagtgtgatg acttgagggt cagctttttc aatttcatca agaagaataa
    27481 ttgagtatgg gttacgacga acacgttcag taagcgtgtt gctattgtcg tcgtagccaa
    27541 catagccagc agttgtaccg attaatttag aaacggctgt gcgatcagag tattcagaca
    27601 tatcaaggcg gataatagca tcttttgagc caaacatatc aagggctaat tgtttagcaa
    27661 gctctgtctt accaacgcca gtaggaccga caaagaggaa actaccaatt ggtcgattac
    27721 cttcgtcaaa gccagcacgg ttacgacgaa tggcacgtga gacggcttca acagcctcat
    27781 cttgtcctat gactttacct ttcaaacggc tagctaattc tttcaagcgt tcaatatcac
    27841 ttgctcccat atttgacacg ggaacaccag ttaatcgttc gacagattct gccacatcat
    27901 taacggtagc tgtaactttt tgcccttccg tatggttgtc aatttgtttt tgcaattctt
    27961 cgatacgaac cttggcattg agagctgctt cgtaatcttc tttagccaca gcattttctt
    28021 gtttttcttt ttggtctgca atttcctttt caagagattt gacatcagtt gcagggtgtt
    28081 gagcagccaa atgagcagca gtcatatcaa tcaagtcaat agctttatct ggtaaactac
    28141 gttgtgggat atattgaatt gaaaaatcaa cagcggcttt taacacatta tcggggagaa
    28201 taacgttgtg gtgtttttca tataaatcac gaattcccat taaaatgtta aagctatctt
    28261 gagcagaagg agcatttact ttaacttcgt tgaaacggcg agcgagcgca gcatttttca
    28321 aaatagtatt acgatactcg tcttgagttg ttgcaccgat aacggtcaat tcgccacgag
    28381 aaagcgcagg tttgagaatg tcagctaagc ctttagaacc agagtcgcca ccagttgacc
    28441 ctgcgcctaa aatttggtgg atttcatcaa agaagagaat gatattacca gcgtctttaa
    28501 cttctttgac aaggttttgg atattttctt caaaagcacc acgatattgt gtgccagctt
    28561 caagaccaga aatatcaata gaaataattt ctttattttt gatagctgct ggcacatcac
    28621 cattgacaat agcttgcgct aagccttcga caacggctgt tttaccaaca cctgcatccc
    28681 caacaaggac aggattgttt ttagtacgac gtgacaagat ttcagcagtt tcttggattt
    28741 ctttgttacg tccaataaca gggtcgagtt cgttagcgcg tgcgcgttcg gtcaagtttg
    28801 ttcctaattt tgccaagata ccatcttctt taggagcaga actaggcgcc ccttcttggt
    28861 attccgcgtt tccagggagc ttacctgttt ggcgatattg tgcaaattct tcaggagtaa
    28921 cttcgcgccc attaatcaaa tagcgtctgt tttctgaatt gtacccgccc atgttactca
    28981 taagttcgtt aaaaatatca tccatatttc caaaaggatt tcttccgtaa aaattattat
    29041 ttgccataaa tattacctct tttcaatcat attttctaaa gtgatactat tatacgattt
    29101 agtatctgga aggttaaatc tctttagtct ttacaaatcg tagtagagag gtcgcattta
    29161 aagagatttc ttaattgttc ctatcaatca ccttctgata ctataatata ctattggtca
    29221 gaaaaagtca aatatttata tgcaaaaaat atgatttttt tttaaaagga agcgttttat
    29281 acgaagctaa accgatacta taatctgttt ttggattttt cccatcttta aaggatattt
    29341 aaaaacatga aaagaataaa atatttcata aaaagtgttg acacaaggag aaatattgga
    29401 tataataatt aaggttttgt aatgaaactg acctaagaca gcaggggagc cgtgctcata
    29461 atattcctgc cgaggcacaa aacgtaatga tgaaataacg tatttgtact ttcgtgtcta
    29521 ggtttaggtg cgaatttttt tgtacctagc ccaaaaataa ttacggaggt aaaactaatg
    29581 agtgaagcaa ttattgctaa aaaagctgag caagttgaag ctgttgctga aaaaatgaaa
    29641 gctgctgcat ctatcgttgt tgtagattca cgtggtctta cagttgagca agatacagtt
    29701 cttcgtcgta atcttcgcga aagcggcgtt gagttcaaag tcatcaaaaa ctcaattttg
    29761 actcgtgcag ctgaaaaagc tggtcttggc gatatgaaag atcttttcgt tggaccatca
    29821 gcagtagcct tctctaacga ggatgttgtt gctcctgcta aaattatcaa tgattttgcg
    29881 aaagatgctg aagcacttga aatcaaaggt ggtgcaatcg aaggttctgt ttcttcaaaa
    29941 gaagaaatcc ttgcccttgc tacattgcca aaccgcgaag gacttctttc tatgctcctt
    30001 tctgtacttc aagcaccagt tcgcaatgtt gcacttgctg tcaaagcagt tgcagacaac
    30061 aaagaagaca acgcggctta atgcgtatgg tagcttaacg ctacaaacaa ttatctaatt
    30121 aaaacaatta atattttgga ggaatctata atggcattga acattgaaaa cattattgct
    30181 gaaattaaag aagcttcaat ccttgaattg aacgaccttg taaaagctat tgaagaagaa
    30241 tttggtgtaa ctgcagctgc tcctgttgct gtagctgctg gtggtgctgc tgacgctggt
    30301 gctgctaaag actcatttga cgttgaattg acttcagctg gtgacaagaa agttgctgtt
    30361 atcaaagctg tacgtgaagt tacaggtctt ggtcttaaag aagctaaagc tcttgttgat
    30421 ggtgcacctg ctaacgttaa agaaggcgtt gcaactgcgg aagctgaaga aatcaaagct
    30481 aaacttgaag aagctggagc ttcaattact cttaaataat agggtgacta ctcaagtagg
    30541 ctaatgaatc ttattaaatc gctattccta ggagtagcga tttttttgtg ttcaaaaagg
    30601 atcaaattgt ttagaataaa aaaacagact ctatagcaaa ctagattttg tatagttctt
    30661 tttatcgatt tctccgctat aagcgaacca tggaagtgtg atgctcatat aaacttcctt
    30721 agcatgctcg ttgaattggt gaaagaaaaa atgtagtgtt ggtgttttat caagatatgc
    30781 aatatttcac gttcttgatg ctaaaagttc attgattcag ccaatatatc ctgaaaatta
    30841 tccgtttcgg taaaatactt tctttcagta aggtaacgat tgataatttg ttcaaaatag
    30901 tgatttagca attcattttt attaacaaaa tatcggtaaa atgttcgtct tgaaacgtct
    30961 gacaaatcaa gaacatcctt aattttgatg tcctcatagc tttcattttc ttgtttttat
    31021 agctatatat taatctcatt ctatcactct aatctaaaat atagataaaa taatgcccac
    31081 ataaaaatgt ttttacaaaa tgataagata agtataaaat tttaatccaa ttaagcttcg
    31141 ttttatctag ttttggtaag tttcttctgt aatgcgaaaa aattttagat ccctgcccaa
    31201 taatagacag tctttctaaa attatgatga gatatgacag gttgaaggag ctgtgacgta
    31261 tgcaaaataa ttctttttat tacatgtcag tcatctattt gattattttc tttgtggcaa
    31321 ttatttacaa tattgcccat ttaaatatgg tatttgtgta tttatggtcg gcgctttttt
    31381 taggaaattt agctttctta atatatagtt tcgttaaaaa tcataagaaa aataaatagc
    31441 aataagctga taccaatgcg attatagcaa gaaagccctc tttttttgaa agggggcttt
    31501 tatgatatgt tagctaatac ttgcgataag gctatcagca gttgttgtcg gcaagatacg
    31561 gatacggtct aatgataata agccgtcgct agcactggca ataccttcgt tggtcgttac
    31621 gccgagttta taattaaggt ttgctgcaat ttgaagtgtt gtgtcagaat aacgcccagc
    31681 tggataggcg atagcgatag tatcttgatt aagattggta tcgagatagt ttttagaatc
    31741 ctccatttca gaagtctgag ttgcgttatc actagctgat aagtcgggat gtgtcacggt
    31801 gtggtcttgg aaagacatgc cgtttgcttt catttctaac atttcatcaa gtgataaatt
    31861 tccgctattt ccaacagtgc ttgtaatgac attgtttgtt gcttttgcac cgtatttttg
    31921 taagataggg taagcgttgt cataaaaatc ccaaagacta tcatcaaacg ttaaccaaac
    31981 aattttacta ttgtcgtttg gaagcacatt ttcggttaaa actttgtagg cttcttcagg
    32041 tgttaaaaag tagtaacctt cttcagaaag acgttgaata tggctttcaa atgttgtcgg
    32101 atcgacgatg agattagcat ttgaagcttc ttccgcagcc ataacgtgga tagcgtgata
    32161 cataagaatg ggtacagaga catttgaatc ctgttttacc cagttaacct cgttttcatt
    32221 ggtattagca gaagagctgt cgcttgtcac cgttgatgca gaagaagttg tggtagtatt
    32281 tgtatggcta gcacttgatg atgacacttg ttcggtttta gttgttgaaa aaatgaagtt
    32341 gttctccttt aaagctataa aaagaaaaac acttgcgaca atacaggcta ttaatagaat
    32401 aatatttata atagctaatg gcttgttgct atgtttttga tgttgacgac gtttttccat
    32461 aatatttaac gatctcctcg caaaagtcta ctcctattgt actatttttt taagacaaag
    32521 ggaactgttt actgtaaatt atggaaagat tttcaaagga cgttattttt ctgtaaattc
    32581 tgaataattt tatggtataa tgtaggaaat gtttttattt gagagtggga cagagatcag
    32641 tagtttcttt gaaacttgat ttttcaataa gttttaattt cttattgttg cctaaaacag
    32701 ttcactgaac tgttttattc ccacttccgc acagtttgag tagggttgta aaagctgatt
    32761 gatcagcgaa ttagaaccca ctcaaccact gcgtcttatt aatgataaca aacataaaca
    32821 aatgaaattg ggtactttag ttcaatttct gttcgaaatt tgcttattaa ggagaaaaag
    32881 atgtcgataa aaattgcttt actcggtttt ggtactgttg ccagtggtgt tcccttcctt
    32941 ttgaaagaaa atccatcaaa aattactgaa gcagcccatg acacgattga aatcactaag
    33001 gttcttgtca aagatgatga cgaaagaaat cgtttattag ctgctggaaa tgattataat
    33061 ttcgttacaa atattgatga cattttgagt gatgatagca ttgacattgt tattgaatta
    33121 atgggacgta ttgagcctgc tcgtacattt attacaaaag cacttgaagc aggaaagaat
    33181 gttgtttctg ccaataaaga cttgattgcc actcatggta aagaattaat tgaacttgct
    33241 aaagacaagg gtgttgcttt ctattatgaa gcagctgtcg ctggtggtat cccaattctt
    33301 cgtacacttg ctaattcgct tacttctgat aaagttacac gtattttggg tgttcttaat
    33361 ggtacatcta actttatgat gactaaaatg gttgacgaag gttggactta cgaagatgcg
    33421 cttaaaacag ctcaagatct tggttatgct gaaagtgacc caacaaatga cgtcgaaggt
    33481 atcgatgcag cctataaagc tgttatttta agccaatttg gttttggaat gacgattgat
    33541 tttgatgatg ttgcacataa gggaatcaca acaatcacac cagatgatgt tgctgtcgct
    33601 caagaacttg gctatgtcat caaattggtc ggagatgtgc gtgaagttga atcaggtatt
    33661 tcagcagaag tttcaccgac tttcttgcca aaagcacatc cacttgctag tgtcaacgat
    33721 gttatgaatg ctgtttttgt ggagtcaatc ggtatcgggg aatcaatgta ttatggacct
    33781 ggtgctggtc aaaaaccaac agcaacgtct gtaactgctg atattatccg tatttgtcgt
    33841 cgtattaaag acggtaatgt tgggaaacca tttaatgaat ttgttcgtga aacaaaattg
    33901 gcaaatcccg ctgatgtgaa gagtcactat tactttgcga ttaatacccc cgataaaaaa
    33961 ggtcaattgc ttcgtttagc tgaaattttc aattctgaag atatttcatt tgaacaagtg
    34021 cttcaacaaa aagccaatgg tacacgtgcg cgtgtggtta tcatcacaca ctcaatgagt
    34081 aaaacacagt tggctgatgt aacagctaaa ttggaagcgg tagaagattt ccaagtggtt
    34141 aatacactta aagtattagg cgaataataa taactgatta agtgaaagga aaagctcaag
    34201 actacttttg agtatgataa tgatatgaaa attacagtac cagcaacctc tgctaatgtt
    34261 ggaccaggct ttgattcggt cggcgtagcg gtttctaagt acttaacgat tgagatttta
    34321 gagctttctg aaagatggga ggttttacat gatttggggg atgttcctag tgacgaaacg
    34381 aatcttttga ttacgacagc tttacaagtg aaagctgacc tacaaccaca tcgtattaaa
    34441 atggtttcag atatcccatt ggcacgagga ttagggtcgt cttcatcagt tattgtagct
    34501 ggaattgagt tagctaatca gctggctcat ttacagcttt cagctgatga aaaattggtg
    34561 attgcgacaa aaattgaagg gcatccagac aatgttgcgc cagctatttt tggtaatctt
    34621 gttatttcat cttatgttaa tgaaaaggtc aatagtgccg ttgttgcctt tcctgaagcc
    34681 tcttttgtgg cgttcattcc taattatgaa ttaaagacta gcgatagccg caatgtattg
    34741 ccaaatgagt tttcttataa ggaagccgtt gctgcctcat caattgccaa tgtagctatt
    34801 gcagcgcttc taacaggtga tttggaaaaa gctggaaaag cgattgaagc tgaccttttc
    34861 catgaacgtt tccgccaaaa attagttaaa gaatttgcac cgattaaaga agtagctcac
    34921 gaggttggtg cctacgcaac ttacttatct ggtgcaggtc caacgattat ggtcttggct
    34981 ccaaaagcaa aagaagcaga gcttgttgag tgtcttgcag cgcttgcttt ggatggtgaa
    35041 gttgtcgcac tccacgttga tactaaagga gtttttgttg aaaaagacta atttggggat
    35101 tttgtttggc ttaataacct atattttgtg gggcttttta tccctttatt ggaaattact
    35161 ttcaggtgtt aattcatata acaccttttc ttatcgcatt atttttactg ttttaacaat
    35221 gttggtttac atggttttat ccaaaaataa ggagcgatac cgtggtgaaa ttcgccaact
    35281 tatcagtcat aagcaagaac ttgctatggc tgttttggca agttttttga ttgcattgaa
    35341 ttggttaact tatatctttg cagttagtca ccagcaggca acacaagcta gttttggcta
    35401 ttatattatg ccccttgtgt caatattatt agcattagtt ttcctacatg aacgattgac
    35461 tccatggatg actgctgcga ttatcattgc aggcattggt gtgggaattt tagcaattaa
    35521 tacagggcaa gcgcctcttg tttcgatact gttagcagtc acttttgctt tgtatggact
    35581 ggttaagaaa aatgtcaagt tatccagtga cgttgccatg ttgatagaaa gtagtgttgt
    35641 cgcccctttt gtgcttatct atttgctatt cttttcaaaa gaaagtttat tagattatag
    35701 cttgctagaa aacgtgttac ttttagcatc tggcattgtg acggcgattc ctttgttgct
    35761 gtttgcagaa gcggtaaaac gtgcgccgtt gaatatcatt gggtttatcc aatacatcaa
    35821 ccccacaatt caactggcaa tagccgtgtt cgtttttcac gaaaaggtag gcaatggaga
    35881 agttagtggt tttattttca tctggatagc gattgctatt tttatcttag gacagctgat
    35941 gtcgttgcgg aagaaaagca ggtaaagaca aggagtttgg atgcataaaa agactgtggt
    36001 tgatttcaaa gaattgggac accaattaat ttttgaaaat ccagtaagaa tattagcaac
    36061 aaagttaatt ggtgatgtag atgctattct taagaaggta gttcacaagg atattgtgtt
    36121 gttggttatg tcagttatga ggcaggaaaa gtatttgaaa acaatttttc tgtaaagact
    36181 tttcctcttg ataacgagat gaatatcaca atgccacaag tttgggaatc taagacggat
    36241 aaagatgaat atgagaaagc tatctcagaa attagacaac aaattcgtca gggaaatatt
    36301 tatcaagtta attatactgt acaacttcat aatagaatta attcgaatct ttttgagctt
    36361 tacaatcgga tagtgattga acaaggcgcc aaatataatt agtatattga acatgatgat
    36421 tttgccatct tatcaatgag tccagaatta ttttttgaaa aaatggttca aaattgacaa
    36481 tacgtccaat gaaagctacc attgctcgtg ggattaatga tgcgcaagat tttagaaata
    36541 aacattggtt agctaatgat agtaagaatc gctctgaaaa tatgatgatt gtcaatcttc
    36601 taagaaatga tacgggacgt attttagggt gattttattg gaatgtgttt gcctcacgat
    36661 gacagagcaa tttttaacat tgctattaga acaattcagg taaaggatga tcaagcaata
    36721 tacggtgttg gtgggggatt acttgggata gtgaatggga aagtgagtac agagaaacac
    36781 tgcttttttg tataaatcac agcccacatt cgatatttta acagctgcta agatgacaca
    36841 aaaaaggtaa ttttccttaa agagcataca aagcgtttaa aaaagttcgg ctcgattttt
    36901 gggatggcct ttttctgaaa cagaattttt agataaaatt tcaaaattgc ttaagacatt
    36961 agatttgtct gattatcgtc taagggtatt acttcataaa tctggtgaag tgtcgatgtt
    37021 ggaagatttg ccctcaacgt ttttacaggc taaattggtt caaagagaag aagcgtgtga
    37081 tttccccttt acctatttta aaacaagtta tcgccctcat attcctaatt ctgataagga
    37141 acaagttttc atttctagtg atggctatcc gcaagaaact tcaataggga atattatttt
    37201 agaaatcaat gggacttatt atactctgat agttgaagtt ggaatattag atggtatgca
    37261 taggaagtat tttatttaac aaggagaagt aactgcacgc tatttagcaa agacagattt
    37321 ggagaatgct aaccatattt ttctgtgtgg taatagcgtt cgtgggcttt aataagatag
    37381 atattatata acctcattct attttttcaa gttattgaag tcaaaatcat tatatattgg
    37441 aactatggtt acttaaataa agctggataa aatatcctct ctagcgtaac aaatgatctt
    37501 ctggtaccaa gtcatctcga ttatagtctg gattttcgtt atggaacata tcctcacttc
    37561 tagcttgtta ttatctctgt tgtactgctc catacaaaaa gcccttagaa actgttgttt
    37621 ccaaggggaa ggggctttgt cttcagtatg aaactttatt taaagaaagt ctgattatca
    37681 agttttttag tgatttcttg tgctataata gaagtattat tgtaaagtca agacagaaag
    37741 ggtaaaacat agaccaaaaa ctcattgtga aaagattttg ttcggaaatg acggttttac
    37801 ttttctttat tttatgagta tttttggtcg tattgggaaa ttcactgatg aattatcaag
    37861 aagctttaga ttggattcat agcaagttaa aatttggaat taagcctggt ttggaacgga
    37921 tggcttggat attggaagaa cttgggaatc ctcaggagaa gctatcagct gtccatattg
    37981 tcggaacgaa tggtaagggg tcagtgacta gctatttaca gcatattttt tcactagctg
    38041 gttatgaggt cgggacattt acatctcctt acattgttaa ctttcgtgaa cgtattagtt
    38101 taaacgatca aatgatttca gagactgatt ttcttgactt ggttgagcgt gttcgtccag
    38161 tagtggaacg tttgccgctt gaaacgactt tagaacctgc gacagaattt gaagttatca
    38221 cggtcttgat gtttgaatat tttgggcata tgcaccctgt tgatattgct tttatcgagg
    38281 caggtatggg tggcctttat gattcgacaa atgtttttaa agctttagcg gttatttgtc
    38341 cttcaatcgg tttagaccac cagaatgttt tagggcagac ttatgcagaa attgctgagc
    38401 aaaaagcagg tgtcctgaaa gaacatgttc cattcatttt tgccactgaa cgtgatgatg
    38461 ttcatcgtgt tttcctcaaa aaagcgcaag cttgcggcag ccaaacgtat gaatttaaaa
    38521 aggatttttc ggttaatgaa actgaaaatg gctttgatta tcaagggcaa gaaaatatcg
    38581 aggatattcg tttagcaatg ccaggtaaac atcagattag caatgctagc cttgctatta
    38641 cggctgcgtt gctattaagt aaaacgtatc caaaagtcac caaagaaatt atcaaatctg
    38701 gcttggcaca gacacattgg gttgggcgaa cagagcttat gttcccaaat gtgatgattg
    38761 acggcgcaca caataatgaa agcgttcaag ctctcgttaa tgtcatgcag gcgtacaagg
    38821 ataaaaattt gcacatttta tttgcagcta ttgatacaaa gccgattgac tcgatgttag
    38881 cattgcttag tcaactagcg gaagttgatg taacgacgtt tgagtatcac aattcgcttg
    38941 ctttggaaaa ttacccagaa cagtatcata aagttccaga ttggaaggac tgggttaagc
    39001 acatcgatag tgacagtaaa gatgattttt accttatcac ggggtcgctc tatttcatat
    39061 cacaagtacg tcctgtgctt ttgtcaagac agcaaaatta agctataata gaaaaaataa
    39121 aaaagattgg aagagataat ggcaaatcaa gaaaaactcg aactagcagt ttaccaactt
    39181 ttagaagcct tgggagaaaa tcctgagcgt gaagggttat tggatacccc aaaacgtgtt
    39241 gctaaaatgt accaagagat gttttcaggc ttaaatgaag acccaaaaga tcaatttaca
    39301 gctgttttta cagaaaatca tgatgaagta gttttagtta aagatatccc gttttattca
    39361 atgtgtgaac atcatttggt tcccttttat gggaaagctc atgttgctta tttgccaagt
    39421 gatggtcgtg tgactggttt gagtaagtta gcgcgtgccg ttgaagtggc tagtaaacgt
    39481 ccacaattac aagaacgttt gactgaccaa gttgctactg cacttgaaga agctttgcat
    39541 cctaagggcg tttttgtcat gcttgaagca gagcatatgt gtatgacaat gcgtggcatc
    39601 aagaaacctg gtagcaaaac cgtaacaacc gttgcaaaag ggattttcaa agaaaatcgt
    39661 gaagaacgaa atgaaattct atcattgatt ttaggaaaat aagaccttac tgacacgtta
    39721 gcatataagg ggagacatta tgaaaattgg aaaatatgag attgacggaa cggcttgtat
    39781 catggggata cttaatgtga ccccagattc tttttctgac ggcggttctt acacttctat
    39841 tgaaaatgcc cttgctcagg ctgaaaaaat gattgcagga ggggctaaga ttattgatgt
    39901 tggtggtgaa tcaactcgtc caggctatac tttcgttgaa gccgaagaag aaattaatcg
    39961 tgttgttcct gttatcagtg cgctcaaaga acgttttgat gttttggtta gtattgatac
    40021 atataagact gaaacagcac gggctgcctt ggaagcaggt gctgatattt taaacgacgt
    40081 ttgggctggt ctttatgacg gaaaaatgct ggcgctggca gctgagaaaa atgttcctat
    40141 cattttgatg cataatcaag aggaagaaaa atacgataat atcactaaag aagtttgtga
    40201 ttttttaaca gaacgtgccc aagctgcttt ggacgcaggc gttacgcttg aaaatatttg
    40261 gattgaccca gggtttggtt ttgctaaaaa cgaggcacaa aatatcgaat tgctaaaagg
    40321 attagatgcg gtttgtaagc tcggttatcc agttcttttt ggaatgtcac gtaaacgtac
    40381 ggttgattat ttgcttggtg ggggaacgtt agctgccgaa cgtgatatgg gaacagctgc
    40441 tttatcagct tgggctgtcg caaaaggttg ccaaattgtt cgtgtacata acgttgacgt
    40501 taatcgtgac attgttaaag tgattagtca actgagttga aaggggtagg agagaaatta
    40561 tctttgccac tgggtaggga tttttctttt ctgattgatt actaatatgg ataaaataca
    40621 tttaaaaggt tgccgttttt atggctacca tggggcgttc gctgaagaac aaacgcttgg
    40681 tcagattttt gtcgttgatt gcaccttgtc tgttgattta caaaaagcat cacagtctga
    40741 tgtgctagaa gatactgttc attatggact ggtttttgaa acgataaaaa gacaagttga
    40801 agaagaacgc tacgctttaa ttgaacgttt ggcaggagca atttgtcaag atatttttga
    40861 acaatttcct ccagttcaag ccattaacat taagattttt aaagaaaatc cgccaatcaa
    40921 tgggcattat gatgtggttg gtattgagtt agaacgggag cgcgcatgac aaaggtttat
    40981 ttgagcttag gaagcaatat cggcgataaa aaagcttatt tactggctgc gcttgaacgc
    41041 ttagaacaat tagcacagac ttctgtgacg tcggtctctt cattttatga gacagcagca
    41101 tggggaaaga cagaccagga tgattttttg aacatttgtt gtgagctcga gacagatttg
    41161 acgccgcaag aattattgc
//
